Best TWAS P=1.82e-10 · Best GWAS P=3.46e-12 conditioned to 0.00527
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TSHR | 0.11 | 0.10 | lasso | 3 | 0.10 | 9.4e-12 | 6.5 | -6.4 | 1.8e-10 | -0.92 | 0.05 | 0.95 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | STON2 | 0.09 | 0.06 | blup | 92 | 0.07 | 2.8e-08 | 6.5 | 5.4 | 5.9e-08 | 0.79 | 0.03 | 0.97 | FALSE |