[Hub]/) : Traits : Blood White Count :

chr17:6,544,116-8,871,015

Best TWAS P=6.43e-13 · Best GWAS P=6.43e-17 conditioned to 1.81e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTC1 0.26 0.07 enet 22 0.08 6.9e-07 -6.3 5.4 7.7e-08 -0.03 0.81 0.19 FALSE
2 GTEx Adipose Subcutaneous RP11-849F2.8 0.16 0.08 lasso 9 0.07 3.5e-06 -6.3 6.7 2.7e-11 -0.07 0.55 0.42 FALSE
3 GTEx Adipose Visceral Omentum RP11-849F2.8 0.16 0.00 lasso 9 0.01 1.4e-01 -4.8 6.8 9.4e-12 -0.06 0.04 0.76 FALSE
4 GTEx Artery Tibial RP11-849F2.8 0.09 0.04 lasso 5 0.05 1.2e-04 -4.8 5.9 4.1e-09 -0.06 0.84 0.10 FALSE
5 GTEx Brain Caudate basal ganglia RP11-199F11.2 0.41 0.05 lasso 6 0.13 1.3e-04 -2.2 5.8 7.4e-09 -0.39 0.05 0.28 FALSE
6 GTEx Colon Transverse LSMD1 0.28 0.12 lasso 5 0.19 3.3e-09 4.5 5.7 1.4e-08 0.12 0.98 0.00 FALSE
7 GTEx Colon Transverse RP11-849F2.8 0.18 0.12 enet 25 0.10 2.5e-05 -6.4 5.2 1.9e-07 -0.09 0.58 0.37 FALSE
8 GTEx Lung CTC1 0.16 0.09 lasso 7 0.12 9.9e-10 -5.6 5.5 3.2e-08 -0.04 0.98 0.02 FALSE
9 GTEx Lung RP11-849F2.8 0.12 0.08 lasso 5 0.09 1.2e-07 -4.1 5.3 1.4e-07 -0.06 0.94 0.06 FALSE
10 GTEx Nerve Tibial RP11-849F2.8 0.22 0.09 enet 30 0.13 3.3e-09 -4.1 7.1 1.7e-12 -0.03 0.88 0.10 FALSE
11 GTEx Stomach RP11-849F2.8 0.16 0.01 enet 19 0.04 7.9e-03 -7.3 6.4 1.2e-10 -0.04 0.04 0.72 FALSE
12 GTEx Testis CYB5D1 0.37 0.12 lasso 4 0.12 4.2e-06 5.6 5.1 3.0e-07 0.09 0.98 0.00 FALSE
13 GTEx Whole Blood CTC1 0.13 0.09 lasso 8 0.09 8.6e-09 -6.3 6.8 8.5e-12 -0.08 0.95 0.05 FALSE
14 GTEx Whole Blood RP11-849F2.8 0.10 0.06 lasso 8 0.05 1.6e-05 -5.5 5.9 2.9e-09 -0.06 0.94 0.05 FALSE
15 METSIM Adipose CTC1 0.13 0.07 enet 25 0.08 5.8e-12 -6.3 5.4 6.1e-08 -0.05 0.96 0.04 FALSE
16 METSIM Adipose RP11-849F2.8 0.13 0.11 lasso 3 0.11 3.2e-16 -5.5 5.7 1.4e-08 -0.05 0.99 0.01 FALSE
17 NTR Blood C17orf68 0.03 0.03 lasso 3 0.03 3.9e-11 -5.6 5.4 5.6e-08 -0.04 1.00 0.00 FALSE
18 ROSMAP Brain Pre-frontal Cortex VAMP2 0.20 0.17 bslmm 412 0.20 1.7e-25 -4.1 5.6 2.2e-08 -0.08 1.00 0.00 FALSE
19 YFS Blood ACAP1 0.33 0.21 enet 34 0.29 1.1e-96 -8.4 6.9 5.0e-12 -0.85 0.00 1.00 TRUE
20 YFS Blood CYB5D1 0.28 0.19 bslmm 488 0.24 5.9e-79 5.6 -6.6 4.0e-11 -0.10 1.00 0.00 TRUE
21 YFS Blood PFAS 0.27 0.06 enet 88 0.16 2.1e-50 -6.8 -5.3 1.4e-07 0.01 0.62 0.38 FALSE
22 The Cancer Genome Atlas Bladder Urothelial Carcinoma CYB5D1 0.04 0.03 blup 40 0.02 1.6e-02 4.6 -5.6 1.9e-08 -0.11 0.03 0.05 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma ACAP1 0.03 0.02 blup 60 0.01 1.5e-03 3.3 6.0 2.2e-09 -0.45 0.12 0.15 FALSE
24 The Cancer Genome Atlas Lung Adenocarcinoma CYB5D1 0.05 0.03 blup 40 0.03 1.9e-04 4.6 -5.8 8.8e-09 -0.10 0.06 0.03 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RANGRF 0.05 0.01 blup 46 0.02 4.0e-03 -3.4 -7.0 3.3e-12 0.03 0.01 0.88 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma PFAS 0.05 0.06 enet 6 0.03 1.5e-04 -7.3 -7.2 6.4e-13 0.07 0.01 0.99 TRUE
27 The Cancer Genome Atlas Thyroid Carcinoma C17orf44 0.04 0.01 enet 9 0.01 4.0e-02 -6.3 6.2 4.5e-10 -0.05 0.02 0.55 FALSE