Best TWAS P=2.79e-24 · Best GWAS P=2.87e-31 conditioned to 1.78e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CLEC4GP1 | 0.70 | 0.58 | bslmm | 425 | 0.69 | 4.9e-116 | -9.9 | -9.0 | 1.9e-19 | 0.62 | 1.00 | 0.00 | FALSE |
| 2 | YFS | Blood | ARHGEF18 | 0.03 | 0.00 | bslmm | 392 | 0.00 | 1.6e-02 | -9.1 | 5.2 | 1.9e-07 | -0.39 | 0.03 | 0.26 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CLEC4GP1 | 0.23 | 0.20 | lasso | 5 | 0.25 | 1.2e-28 | -8.5 | -10.2 | 2.8e-24 | 0.76 | 0.57 | 0.43 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | CLEC4M | 0.10 | 0.03 | enet | 23 | 0.03 | 3.4e-04 | -2.5 | -5.2 | 2.2e-07 | 0.40 | 0.05 | 0.30 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | KANK3 | 0.05 | 0.02 | enet | 8 | 0.02 | 6.1e-03 | 4.8 | -5.8 | 7.4e-09 | -0.04 | 0.00 | 0.84 | TRUE |