TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood White Count
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chr19:6,763,718-8,657,166
Best TWAS P=2.79e-24 · Best GWAS P=2.87e-31 conditioned to 1.78e-10
7M
7.5M
8M
8.5M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
CLEC4GP1
0.23
0.20
lasso
5
0.25
1.2e-28
-8.5
-10.2
2.8e-24
0.76
0.57
0.43
TRUE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
KANK3
0.05
0.02
enet
8
0.02
6.1e-03
4.8
-5.8
7.4e-09
-0.04
0.00
0.84
TRUE
1
CommonMind
Brain Pre-frontal Cortex
CLEC4GP1
0.70
0.58
bslmm
425
0.69
4.9e-116
-9.9
-9.0
1.9e-19
0.62
1.00
0.00
FALSE
2
YFS
Blood
ARHGEF18
0.03
0.00
bslmm
392
0.00
1.6e-02
-9.1
5.2
1.9e-07
-0.39
0.03
0.26
FALSE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
CLEC4M
0.10
0.03
enet
23
0.03
3.4e-04
-2.5
-5.2
2.2e-07
0.40
0.05
0.30
FALSE