Best TWAS P=6.07e-09 · Best GWAS P=3.07e-10 conditioned to 0.0144
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | YFS | Blood | EIF2S2 | 0.07 | 0.07 | enet | 25 | 0.06 | 4.3e-20 | -6.2 | 5.8 | 6.1e-09 | -0.89 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | ITCH | 0.09 | 0.04 | enet | 28 | 0.09 | 2.5e-05 | 4.3 | -5.5 | 2.9e-08 | 0.74 | 0.21 | 0.76 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | RALY | 0.05 | 0.04 | blup | 53 | 0.05 | 1.6e-05 | -4.9 | 5.4 | 7.3e-08 | -0.94 | 0.04 | 0.96 | FALSE |
| 1 | GTEx | Brain Cortex | MAP1LC3A | 0.39 | 0.26 | enet | 16 | 0.33 | 6.6e-10 | -4.1 | 5.4 | 7.6e-08 | -0.67 | 0.86 | 0.12 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | ITCH | 0.09 | 0.02 | enet | 16 | 0.06 | 8.2e-03 | -5.5 | -5.2 | 1.7e-07 | 0.78 | 0.08 | 0.61 | FALSE |
| 4 | GTEx | Cells EBV-transformed lymphocytes | NCOA6 | 0.11 | 0.06 | enet | 15 | 0.06 | 3.9e-03 | 4.8 | -5.1 | 2.7e-07 | 0.44 | 0.12 | 0.53 | FALSE |