[Hub]/) : Traits : Blood White Count : ← →

chr2:159,476,732-161,610,478

Best TWAS P=5.95e-38 · Best GWAS P=1.76e-30 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	YFS	Blood	BAZ2B	0.23	0.26	enet	36	0.34	3.0e-118	10.9	12.9	5.9e-38	0.43	0.41	0.59	TRUE
16	GTEx	Vagina	PLA2R1	0.20	-0.01	enet	15	0.03	8.2e-02	-4.3	11.9	1.1e-32	0.21	0.06	0.40	TRUE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLA2R1	0.24	0.07	enet	15	0.13	1.4e-13	7.6	10.8	5.8e-27	0.12	0.01	0.99	TRUE
18	NTR	Blood	BAZ2B	0.05	0.05	lasso	6	0.05	5.1e-16	9.9	10.7	1.5e-26	0.56	0.79	0.21	TRUE
11	GTEx	Esophagus Muscularis	PLA2R1	0.07	0.07	enet	19	0.07	6.8e-05	7.6	9.1	1.1e-19	0.14	0.67	0.04	TRUE
2	GTEx	Adipose Subcutaneous	AC009506.1	0.07	0.05	lasso	3	0.03	1.8e-03	7.7	-7.4	1.6e-13	-0.42	0.60	0.02	TRUE
4	GTEx	Artery Tibial	AC009506.1	0.11	0.11	lasso	4	0.10	5.5e-08	6.2	-6.2	5.4e-10	-0.40	1.00	0.00	TRUE
5	GTEx	Brain Hippocampus	LY75	0.23	0.10	enet	13	0.06	1.8e-02	-5.7	6.0	1.5e-09	-0.11	0.10	0.05	TRUE
10	GTEx	Esophagus Muscularis	BAZ2B	0.12	0.00	enet	61	0.01	6.3e-02	-1.7	5.7	1.1e-08	0.06	0.12	0.06	TRUE
17	GTEx	Whole Blood	AC009506.1	0.13	0.02	enet	37	0.05	4.3e-05	-8.2	11.0	2.7e-28	0.36	0.57	0.24	FALSE
1	GTEx	Adipose Subcutaneous	PLA2R1	0.09	0.03	enet	24	0.03	1.0e-03	-4.3	10.0	9.2e-24	0.20	0.68	0.09	FALSE
6	GTEx	Cells Transformed fibroblasts	PLA2R1	0.26	0.16	enet	24	0.17	1.4e-12	7.7	9.1	1.1e-19	-0.01	1.00	0.00	FALSE
12	GTEx	Muscle Skeletal	PLA2R1	0.04	0.03	enet	6	0.03	7.8e-04	7.6	8.6	5.4e-18	0.07	0.82	0.01	FALSE
9	GTEx	Esophagus Mucosa	PLA2R1	0.25	0.18	lasso	5	0.27	2.0e-18	7.7	8.0	1.3e-15	0.05	1.00	0.00	FALSE
15	GTEx	Thyroid	MARCH7	0.06	0.01	lasso	15	0.01	7.8e-02	-3.0	-7.7	1.6e-14	-0.48	0.29	0.38	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PLA2R1	0.05	0.04	lasso	5	0.03	1.0e-04	7.6	7.6	2.5e-14	0.05	0.01	0.99	FALSE
20	YFS	Blood	CD302	0.09	0.03	lasso	7	0.07	6.7e-21	-4.4	-7.5	6.3e-14	-0.38	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	PLA2R1	0.06	0.03	blup	128	0.02	5.0e-03	-4.3	7.2	6.4e-13	0.14	0.02	0.84	FALSE
7	GTEx	Colon Sigmoid	PLA2R1	0.19	0.15	lasso	2	0.14	1.2e-05	7.6	7.1	1.1e-12	0.08	0.58	0.02	FALSE
8	GTEx	Colon Transverse	PLA2R1	0.12	0.10	lasso	2	0.07	2.9e-04	-7.0	7.0	2.2e-12	0.06	0.34	0.03	FALSE
13	GTEx	Nerve Tibial	PLA2R1	0.11	0.08	lasso	3	0.08	3.7e-06	5.8	7.0	2.5e-12	-0.02	0.95	0.01	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLA2R1	0.05	0.03	blup	127	0.04	5.3e-09	-4.3	6.7	1.7e-11	0.08	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PLA2R1	0.06	0.01	blup	124	0.00	8.4e-02	7.6	6.6	4.8e-11	-0.10	0.01	0.95	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLA2R1	0.06	0.01	blup	121	0.01	1.5e-02	7.6	6.5	1.2e-10	0.05	0.01	0.94	FALSE
14	GTEx	Nerve Tibial	AC009506.1	0.06	0.04	lasso	4	0.04	1.2e-03	6.5	-6.2	4.4e-10	-0.59	0.05	0.86	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	PLA2R1	0.03	0.01	lasso	2	0.01	1.5e-02	-5.2	5.8	8.4e-09	-0.05	0.06	0.35	FALSE
3	GTEx	Artery Tibial	PLA2R1	0.15	0.02	lasso	4	0.03	2.0e-03	5.8	5.5	4.2e-08	-0.07	0.78	0.02	FALSE
21	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CD302	0.18	0.00	enet	11	0.02	1.2e-02	-7.3	-5.4	6.1e-08	0.25	0.02	0.10	FALSE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LY75	0.14	0.13	blup	114	0.11	3.5e-05	-3.7	5.2	2.1e-07	-0.14	0.62	0.03	FALSE