[Hub]/) : Traits : Blood White Count :

chr2:159,476,732-161,610,478

Best TWAS P=5.95e-38 · Best GWAS P=1.76e-30 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLA2R1 0.09 0.03 enet 24 0.03 1.0e-03 -4.3 10.0 9.2e-24 0.20 0.68 0.09 FALSE
2 GTEx Adipose Subcutaneous AC009506.1 0.07 0.05 lasso 3 0.03 1.8e-03 7.7 -7.4 1.6e-13 -0.42 0.60 0.02 TRUE
3 GTEx Artery Tibial PLA2R1 0.15 0.02 lasso 4 0.03 2.0e-03 5.8 5.5 4.2e-08 -0.07 0.78 0.02 FALSE
4 GTEx Artery Tibial AC009506.1 0.11 0.11 lasso 4 0.10 5.5e-08 6.2 -6.2 5.4e-10 -0.40 1.00 0.00 TRUE
5 GTEx Brain Hippocampus LY75 0.23 0.10 enet 13 0.06 1.8e-02 -5.7 6.0 1.5e-09 -0.11 0.10 0.05 TRUE
6 GTEx Cells Transformed fibroblasts PLA2R1 0.26 0.16 enet 24 0.17 1.4e-12 7.7 9.1 1.1e-19 -0.01 1.00 0.00 FALSE
7 GTEx Colon Sigmoid PLA2R1 0.19 0.15 lasso 2 0.14 1.2e-05 7.6 7.1 1.1e-12 0.08 0.58 0.02 FALSE
8 GTEx Colon Transverse PLA2R1 0.12 0.10 lasso 2 0.07 2.9e-04 -7.0 7.0 2.2e-12 0.06 0.34 0.03 FALSE
9 GTEx Esophagus Mucosa PLA2R1 0.25 0.18 lasso 5 0.27 2.0e-18 7.7 8.0 1.3e-15 0.05 1.00 0.00 FALSE
10 GTEx Esophagus Muscularis BAZ2B 0.12 0.00 enet 61 0.01 6.3e-02 -1.7 5.7 1.1e-08 0.06 0.12 0.06 TRUE
11 GTEx Esophagus Muscularis PLA2R1 0.07 0.07 enet 19 0.07 6.8e-05 7.6 9.1 1.1e-19 0.14 0.67 0.04 TRUE
12 GTEx Muscle Skeletal PLA2R1 0.04 0.03 enet 6 0.03 7.8e-04 7.6 8.6 5.4e-18 0.07 0.82 0.01 FALSE
13 GTEx Nerve Tibial PLA2R1 0.11 0.08 lasso 3 0.08 3.7e-06 5.8 7.0 2.5e-12 -0.02 0.95 0.01 FALSE
14 GTEx Nerve Tibial AC009506.1 0.06 0.04 lasso 4 0.04 1.2e-03 6.5 -6.2 4.4e-10 -0.59 0.05 0.86 FALSE
15 GTEx Thyroid MARCH7 0.06 0.01 lasso 15 0.01 7.8e-02 -3.0 -7.7 1.6e-14 -0.48 0.29 0.38 FALSE
16 GTEx Vagina PLA2R1 0.20 -0.01 enet 15 0.03 8.2e-02 -4.3 11.9 1.1e-32 0.21 0.06 0.40 TRUE
17 GTEx Whole Blood AC009506.1 0.13 0.02 enet 37 0.05 4.3e-05 -8.2 11.0 2.7e-28 0.36 0.57 0.24 FALSE
18 NTR Blood BAZ2B 0.05 0.05 lasso 6 0.05 5.1e-16 9.9 10.7 1.5e-26 0.56 0.79 0.21 TRUE
19 YFS Blood BAZ2B 0.23 0.26 enet 36 0.34 3.0e-118 10.9 12.9 5.9e-38 0.43 0.41 0.59 TRUE
20 YFS Blood CD302 0.09 0.03 lasso 7 0.07 6.7e-21 -4.4 -7.5 6.3e-14 -0.38 1.00 0.00 FALSE
21 The Cancer Genome Atlas Bladder Urothelial Carcinoma CD302 0.18 0.00 enet 11 0.02 1.2e-02 -7.3 -5.4 6.1e-08 0.25 0.02 0.10 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma PLA2R1 0.05 0.03 blup 127 0.04 5.3e-09 -4.3 6.7 1.7e-11 0.08 0.02 0.98 FALSE
23 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PLA2R1 0.06 0.01 blup 124 0.00 8.4e-02 7.6 6.6 4.8e-11 -0.10 0.01 0.95 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2R1 0.06 0.01 blup 121 0.01 1.5e-02 7.6 6.5 1.2e-10 0.05 0.01 0.94 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma PLA2R1 0.06 0.03 blup 128 0.02 5.0e-03 -4.3 7.2 6.4e-13 0.14 0.02 0.84 FALSE
26 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PLA2R1 0.05 0.04 lasso 5 0.03 1.0e-04 7.6 7.6 2.5e-14 0.05 0.01 0.99 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LY75 0.14 0.13 blup 114 0.11 3.5e-05 -3.7 5.2 2.1e-07 -0.14 0.62 0.03 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma PLA2R1 0.24 0.07 enet 15 0.13 1.4e-13 7.6 10.8 5.8e-27 0.12 0.01 0.99 TRUE
29 The Cancer Genome Atlas Thyroid Carcinoma PLA2R1 0.03 0.01 lasso 2 0.01 1.5e-02 -5.2 5.8 8.4e-09 -0.05 0.06 0.35 FALSE