TWAS
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Traits
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Traits
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Blood White Count
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chr3:38,643,279-40,267,321
Best TWAS P=1.12e-07 · Best GWAS P=2.76e-14 conditioned to 2.11e-10
38.6M
38.8M
39M
39.2M
39.4M
39.6M
39.8M
40M
40.2M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
MOBP
0.12
0.04
blup
444
0.05
2.7e-07
-3.4
-5.3
1.1e-07
-0.25
0.98
0.01
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
SCN11A
0.11
0.07
blup
77
0.07
9.4e-08
3.6
5.3
1.1e-07
0.03
0.95
0.05
TRUE