Best TWAS P=1.12e-07 · Best GWAS P=2.76e-14 conditioned to 2.11e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | MOBP | 0.12 | 0.04 | blup | 444 | 0.05 | 2.7e-07 | -3.4 | -5.3 | 1.1e-07 | -0.25 | 0.98 | 0.01 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | SCN11A | 0.11 | 0.07 | blup | 77 | 0.07 | 9.4e-08 | 3.6 | 5.3 | 1.1e-07 | 0.03 | 0.95 | 0.05 | TRUE |