[Hub]/) : Traits : Blood White Count :

chr3:42,051,836-43,826,355

Best TWAS P=1.11e-25 · Best GWAS P=9.86e-28 conditioned to 0.000138

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia POMGNT2 0.21 0.16 lasso 5 0.16 2.3e-05 -4.8 -5.2 1.8e-07 0.51 0.32 0.17 FALSE
2 GTEx Brain Nucleus accumbens basal ganglia POMGNT2 0.36 0.28 lasso 3 0.28 4.7e-08 -5.1 -5.3 1.4e-07 0.43 0.72 0.02 FALSE
3 GTEx Esophagus Muscularis HIGD1A 0.18 0.00 enet 41 0.04 9.8e-04 -7.9 -6.7 1.8e-11 0.66 0.05 0.92 FALSE
4 GTEx Lung ZNF662 0.10 0.00 lasso 5 0.00 2.6e-01 -10.9 10.4 1.6e-25 -0.90 0.01 0.90 FALSE
5 GTEx Pituitary CCDC13 0.34 0.10 lasso 4 0.18 2.6e-05 -3.9 -6.5 5.9e-11 0.37 0.07 0.30 FALSE
6 METSIM Adipose ACKR2 0.05 0.02 enet 7 0.04 6.7e-07 -9.2 7.1 1.3e-12 -0.64 0.09 0.76 FALSE
7 ROSMAP Brain Pre-frontal Cortex ACKR2 0.21 0.13 lasso 6 0.15 2.6e-18 -9.4 -8.6 1.1e-17 0.67 0.95 0.05 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf39 0.03 0.02 blup 50 0.03 9.7e-05 -4.8 5.2 2.6e-07 -0.43 0.01 0.98 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC13 0.03 0.03 blup 59 0.03 3.8e-04 3.6 5.5 2.8e-08 -0.42 0.37 0.03 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma CYP8B1 0.04 0.03 blup 45 0.04 1.3e-04 -9.4 10.5 1.1e-25 -0.85 0.02 0.93 TRUE
11 The Cancer Genome Atlas Thyroid Carcinoma CYP8B1 0.04 0.01 blup 46 0.03 2.3e-04 -9.4 9.0 1.8e-19 -0.72 0.07 0.40 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma HHATL 0.09 0.01 enet 11 0.02 3.1e-03 6.6 -5.4 7.9e-08 0.31 0.01 0.91 FALSE