[Hub]/) : Traits : Blood White Count :

chr4:69,713-1,797,852

Best TWAS P=1.75e-15 · Best GWAS P=2.4e-20 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere RNF212 0.35 0.17 lasso 6 0.18 1.7e-05 4.4 5.5 3.7e-08 0.16 0.48 0.04 FALSE
2 GTEx Brain Putamen basal ganglia RNF212 0.23 0.07 lasso 19 0.05 2.6e-02 4.3 5.2 1.5e-07 0.14 0.14 0.05 TRUE
3 GTEx Cells EBV-transformed lymphocytes PCGF3 0.44 0.24 lasso 7 0.24 2.4e-08 -4.3 5.2 1.7e-07 0.52 0.67 0.19 TRUE
4 GTEx Liver PCGF3 0.27 0.15 enet 10 0.17 1.5e-05 -4.3 6.0 2.1e-09 0.51 0.13 0.22 TRUE
5 GTEx Skin Sun Exposed Lower leg PCGF3 0.60 0.36 enet 30 0.42 4.4e-37 -4.3 5.2 2.4e-07 0.36 1.00 0.00 FALSE
6 GTEx Skin Sun Exposed Lower leg AC139887.4 0.48 0.26 enet 40 0.31 7.7e-26 -4.3 5.4 5.8e-08 0.35 1.00 0.00 FALSE
7 GTEx Skin Sun Exposed Lower leg RP11-440L14.1 0.54 0.32 enet 24 0.38 9.3e-33 -4.3 5.3 1.4e-07 0.39 1.00 0.00 FALSE
8 GTEx Vagina PCGF3 0.43 0.20 lasso 7 0.23 4.5e-06 -4.3 5.3 9.9e-08 0.42 0.16 0.22 FALSE
9 GTEx Vagina RP11-440L14.1 0.36 0.17 lasso 7 0.16 1.5e-04 3.7 5.2 2.4e-07 0.53 0.11 0.22 FALSE
10 GTEx Whole Blood PCGF3 0.26 0.12 enet 18 0.23 6.5e-21 9.2 -6.4 1.2e-10 -0.81 0.00 1.00 FALSE
11 GTEx Whole Blood AC139887.4 0.14 0.06 lasso 6 0.11 4.3e-10 9.2 -7.1 1.3e-12 -0.85 0.00 1.00 FALSE
12 GTEx Whole Blood RP11-440L14.1 0.17 0.05 lasso 6 0.14 2.6e-13 -5.0 -5.4 8.0e-08 -0.69 0.02 0.98 TRUE
13 ROSMAP Brain Pre-frontal Cortex RP11-440L14.1 0.04 0.00 bslmm 329 0.02 2.8e-03 -4.2 6.1 1.1e-09 0.48 0.10 0.38 FALSE
14 YFS Blood MYL5 0.17 0.01 blup 358 0.06 1.4e-17 -1.5 -6.9 5.8e-12 -0.40 0.01 0.99 TRUE
15 The Cancer Genome Atlas Glioblastoma Multiforme PCGF3 0.11 0.00 blup 69 0.05 1.6e-02 6.7 5.3 1.3e-07 0.64 0.02 0.27 TRUE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CPLX1 0.10 0.04 lasso 3 0.04 1.1e-05 9.1 -8.0 1.8e-15 -0.75 0.00 1.00 TRUE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PCGF3 0.11 0.07 blup 69 0.06 2.7e-04 -4.3 6.3 2.6e-10 0.54 0.20 0.50 FALSE
18 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PCGF3 0.18 0.04 blup 70 0.12 2.6e-05 -1.8 5.1 2.7e-07 0.39 0.34 0.19 TRUE
19 The Cancer Genome Atlas Thyroid Carcinoma FGFRL1 0.34 0.05 enet 32 0.17 1.2e-16 3.5 5.5 3.7e-08 0.22 0.00 0.99 FALSE