TWAS hub - FLJ13197

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1280	0.0290	4.7e-08	0.099	0.068	0.101	0.105	0.099	4.2e-12	1.1e-08	3.0e-12	8.8e-13	5.0e-12
2	TCGA	Breast Invasive Carcinoma	0.0385	0.0146	2.9e-07	0.022	0.032	0.028	NA	0.027	2.0e-05	3.2e-07	1.6e-06	NA	2.1e-06
3	TCGA	Cervical Squamous Cell Carcinoma	0.1410	0.0960	9.3e-03	-0.002	0.036	0.020	NA	0.003	4.4e-01	6.7e-03	3.5e-02	NA	2.1e-01
4	TCGA	Colon Adenocarcinoma	0.1250	0.0520	3.1e-04	0.002	0.048	0.027	NA	0.026	2.2e-01	9.1e-04	1.1e-02	NA	1.2e-02
5	TCGA	Esophageal Carcinoma	0.1600	0.0820	9.1e-03	0.036	0.015	-0.007	NA	0.017	2.6e-02	1.0e-01	6.2e-01	NA	8.9e-02
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0613	0.0245	6.2e-06	0.053	0.041	0.038	NA	0.045	1.2e-06	2.0e-05	3.5e-05	NA	8.6e-06
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.1127	0.0346	1.3e-11	0.071	0.099	0.083	NA	0.087	2.1e-08	3.4e-11	1.3e-09	NA	5.4e-10
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0810	0.0360	9.4e-04	0.048	0.031	0.000	NA	0.023	1.0e-03	6.4e-03	3.2e-01	NA	1.7e-02
9	TCGA	Brain Lower Grade Glioma	0.0634	0.0251	1.1e-06	0.042	0.062	0.062	NA	0.050	1.3e-05	1.5e-07	1.3e-07	NA	2.0e-06
10	TCGA	Liver Hepatocellular Carcinoma	0.1080	0.0490	5.5e-04	0.085	0.084	0.075	NA	0.086	8.4e-05	9.2e-05	2.1e-04	NA	7.3e-05
11	TCGA	Lung Adenocarcinoma	0.1102	0.0364	1.5e-08	0.065	0.082	0.072	NA	0.078	4.0e-08	7.0e-10	9.0e-09	NA	2.3e-09
12	TCGA	Lung Squamous Cell Carcinoma	0.0766	0.0301	1.7e-06	0.045	0.060	0.061	NA	0.061	7.7e-06	2.0e-07	1.7e-07	NA	1.7e-07
13	TCGA	Ovarian Serous Cystadenocarcinoma	0.0570	0.0310	4.8e-03	0.004	0.014	-0.003	NA	-0.003	1.6e-01	3.4e-02	6.4e-01	NA	6.0e-01
14	TCGA	Pancreatic Adenocarcinoma	0.1320	0.0540	2.0e-04	0.069	0.082	0.032	NA	0.074	7.8e-04	2.7e-04	1.7e-02	NA	4.9e-04
15	TCGA	Prostate Adenocarcinoma	0.1980	0.0663	2.9e-13	0.100	0.136	0.127	NA	0.126	1.4e-10	4.2e-14	3.8e-13	NA	4.1e-13
16	TCGA	Soft Tissue Sarcoma	0.0790	0.0470	4.4e-03	0.015	0.032	0.041	NA	0.008	4.1e-02	4.9e-03	1.7e-03	NA	9.7e-02
17	TCGA	Testicular Germ Cell Tumors	0.2170	0.0900	2.6e-03	0.049	0.098	0.067	NA	0.082	7.9e-03	2.4e-04	2.3e-03	NA	7.6e-04
18	TCGA	Thyroid Carcinoma	0.1570	0.0470	1.7e-11	0.084	0.133	0.124	NA	0.128	1.4e-08	7.1e-13	4.6e-12	NA	2.1e-12
19	TCGA	Uterine Corpus Endometrial Carcinoma	0.2040	0.0850	1.5e-03	0.012	0.094	0.042	NA	0.036	1.5e-01	1.4e-03	2.6e-02	NA	3.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Blood Eosinophil Count	57.9	446.0	712.9	18.0	25.3	6.4	18.7	18.5	26.7	22.1	22.6	23.3	26.2	20.9	21.1	24.1	20.5	23.4	20.5	9.7	20.9	21.3
Medication: Amlodipine	12.5	17.5	23.6	2.8	4.6	3.4	4.5	3.5	3.9	4.3	4.4	4.5	4.0	4.9	4.6	4.3	4.8	4.4	4.4	2.6	4.6	4.0
Number of treatments/medications taken	7.6	13.8	20.3	2.0	4.1	1.4	3.7	3.8	4.1	3.7	4.1	4.1	4.3	4.0	4.0	4.1	4.2	4.5	3.7	0.7	3.4	3.9
Medication: Blood pressure	7.2	12.6	22.0	1.0	3.4	1.6	3.8	2.2	4.3	3.7	4.7	4.0	4.2	3.9	3.7	3.7	3.7	4.3	4.3	-0.5	2.5	4.1
Medication for cholesterol, blood pressure or diabetes	6.6	11.0	19.4	-1.5	-3.3	-1.9	-3.6	-2.1	-3.7	-3.3	-4.4	-3.6	-3.6	-3.8	-3.5	-3.3	-3.9	-4.1	-3.7	-0.0	-2.8	-3.6
Medication: Atenolol	6.2	7.7	11.4	1.1	2.6	2.4	3.0	2.5	2.6	3.0	3.0	2.6	3.0	3.4	3.3	2.4	3.4	3.3	2.5	2.0	3.0	2.8
Hypertension (Self-reported)	5.9	16.4	25.5	3.1	4.5	1.8	3.8	3.2	4.5	3.6	5.0	4.7	4.9	4.3	4.1	4.4	4.6	4.8	4.1	0.8	3.6	4.4
Vascular/heart problems diagnosed by doctor	5.9	16.1	24.6	-3.4	-4.6	-2.1	-3.9	-3.1	-4.0	-3.5	-5.0	-4.7	-4.6	-4.5	-4.1	-4.2	-4.7	-4.6	-3.9	-0.8	-3.9	-4.2
Blood Red Count	5.6	53.6	80.5	5.1	8.3	4.4	7.2	7.4	8.3	8.1	6.7	8.1	8.2	7.0	7.3	9.0	6.8	7.3	8.7	4.6	7.1	7.5
Number of self-reported non-cancer illnesses	5.6	9.7	14.7	2.4	3.8	1.5	3.2	2.5	3.1	3.0	3.7	3.5	3.4	3.3	3.0	3.6	3.6	3.5	3.4	-0.0	3.2	3.0
High blood pressure	5.3	14.9	22.2	3.1	4.3	2.0	3.7	3.1	4.0	3.6	4.7	4.5	4.5	4.2	4.0	4.1	4.4	4.6	3.8	1.1	3.7	4.1
Illnesses of siblings: Diabetes	5.2	6.4	10.4	2.3	2.9	1.3	1.7	3.0	2.8	2.7	2.3	3.2	2.7	2.0	2.1	2.9	2.6	2.8	2.9	1.8	2.9	2.2
Alcohol drinker status: Previous	5.2	6.0	11.0	2.0	2.5	1.4	1.4	3.3	2.8	2.6	2.1	2.5	2.9	1.4	2.3	3.3	2.4	2.0	2.6	2.7	1.9	3.0
Illnesses of siblings	5.0	7.0	12.3	-3.1	-3.4	0.2	-1.9	-2.4	-3.5	-2.0	-3.0	-3.4	-3.5	-2.5	-2.2	-3.2	-2.5	-3.2	-2.1	-0.5	-2.5	-2.2
Hypothyroidism (self reported)	4.6	10.5	23.4	3.2	3.9	1.7	1.9	4.8	3.1	3.3	2.0	4.0	3.3	1.9	2.5	4.7	2.2	2.4	3.9	3.2	2.9	4.0
Medication: Aspirin	4.4	5.7	10.6	0.8	2.3	1.0	2.6	1.6	2.9	2.4	3.3	2.6	2.3	3.0	2.5	2.2	2.8	3.0	2.4	0.1	1.7	3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.3	5.0	11.0	1.4	2.7	-0.2	2.0	1.6	3.1	2.0	2.5	2.5	3.3	2.4	2.2	2.6	1.8	2.8	2.3	-0.1	1.9	2.0
Ever had stillbirth, spontaneous miscarriage or termination	4.0	4.3	8.5	-2.2	-2.6	-0.7	-1.1	-2.8	-1.7	-1.3	-2.1	-2.9	-2.0	-2.0	-2.1	-2.5	-2.1	-2.3	-1.0	-1.7	-2.4	-1.9
Long-standing illness, disability or infirmity	3.9	6.0	11.8	1.4	2.9	0.8	2.5	2.4	2.8	2.1	2.7	2.3	3.4	2.8	2.4	2.7	2.8	2.5	2.8	0.4	2.4	2.4
Hypothyroidism/myxoedema (self-reported)	3.7	7.2	18.3	2.6	3.3	1.5	1.6	4.3	2.3	2.4	1.7	3.4	2.6	1.6	2.1	4.0	2.0	1.9	2.9	2.9	2.4	3.3
Cardiovascular Disease	3.6	12.0	22.2	3.2	4.1	1.3	3.5	1.9	3.8	3.1	4.7	3.8	3.9	4.0	3.4	3.6	4.0	4.2	2.9	0.2	3.2	3.8
Ever had bowel cancer screening	3.5	4.0	6.7	1.4	2.1	1.5	2.6	1.2	1.9	2.4	2.2	2.2	1.9	2.3	2.2	2.2	2.2	2.5	1.7	0.8	2.0	1.9
Blood Platelet Count	3.4	39.6	57.9	-4.3	-6.8	-6.5	-5.7	-7.5	-4.9	-6.5	-5.4	-7.3	-4.5	-5.9	-6.1	-7.6	-6.8	-5.7	-7.1	-6.0	-6.5	-7.0
Overall health rating	3.3	7.2	16.6	1.2	3.1	0.1	1.9	3.3	3.7	2.5	2.5	2.7	4.1	2.5	2.4	3.1	2.2	2.3	3.1	1.3	2.1	3.6
Breast cancer (self-reported)	3.3	3.9	7.0	1.1	2.4	1.0	2.3	1.6	2.1	2.1	1.9	2.0	1.9	2.6	2.4	2.0	1.6	1.9	1.9	0.8	2.1	2.6
Standing height	3.2	31.3	54.8	4.5	6.4	5.3	7.2	4.6	3.6	6.3	4.6	5.6	3.5	7.4	6.8	5.7	5.9	5.8	3.8	4.9	7.4	4.4
Medication for cholesterol	3.2	4.8	8.1	-1.9	-2.6	-0.5	-2.2	-2.2	-2.2	-2.1	-2.4	-2.8	-2.1	-2.3	-2.2	-2.8	-2.2	-2.7	-1.7	-0.5	-1.6	-2.9
Blood White Count	3.1	23.2	84.3	-3.4	-4.4	-4.9	-1.0	-8.8	-2.8	-4.8	-1.4	-5.6	-2.6	-2.3	-4.4	-6.1	-3.7	-2.8	-4.2	-9.2	-5.3	-4.7
Mouth/teeth dental problems: Loose teeth	3.1	3.7	8.4	2.9	2.2	2.2	1.3	2.2	0.3	1.5	1.9	2.4	-0.1	1.7	2.0	2.2	2.6	1.7	1.2	1.3	2.0	2.2
Leg fat-free mass (right)	3.1	16.4	25.2	1.5	4.2	2.7	4.6	4.6	4.2	4.0	3.7	4.5	4.0	4.7	4.3	4.9	3.5	3.8	4.7	3.2	3.3	5.0
Leg predicted mass (right)	3.1	16.4	25.3	1.4	4.2	2.7	4.5	4.7	4.2	4.0	3.7	4.5	3.9	4.6	4.3	4.9	3.5	3.7	4.7	3.2	3.3	5.0
Medication: Blood pressure	3.1	5.8	8.6	2.3	2.7	1.1	2.2	2.9	2.2	2.2	2.0	2.8	2.9	2.6	2.6	2.9	2.5	2.6	1.8	2.1	2.4	2.4
Emphysema/chronic bronchitis	3.0	3.3	7.2	-0.9	-1.9	-1.0	-2.5	0.4	-2.3	-2.3	-2.6	-1.4	-1.9	-2.2	-2.3	-1.5	-1.8	-2.7	-1.2	0.5	-2.0	-1.0
Alzheimer’s Disease (in father)	2.9	3.1	6.0	2.4	2.3	0.5	1.3	2.1	1.6	1.8	1.1	2.2	2.0	1.6	1.6	2.1	1.5	1.6	1.3	1.8	2.1	1.7
Schizophrenia (2014)	2.9	6.3	12.3	-2.9	-3.0	-2.1	-2.2	-2.0	-2.2	-2.5	-2.3	-2.6	-2.5	-2.3	-2.9	-2.5	-2.9	-3.0	-1.5	-2.5	-3.5	-1.3
Basal metabolic rate	2.9	16.0	23.6	1.7	4.3	2.7	4.6	4.5	4.0	4.1	3.3	4.6	3.8	4.7	4.2	4.9	3.2	3.6	4.4	3.5	3.6	4.8
Weight	2.8	13.5	25.4	1.4	3.8	2.3	3.7	5.0	3.7	3.9	2.5	4.2	3.5	3.9	3.6	4.7	2.6	3.0	3.9	4.5	3.0	4.6
Hip circumference	2.8	11.9	25.1	1.0	3.5	2.4	3.2	5.0	3.4	3.6	2.3	3.9	3.1	3.4	3.4	4.5	2.4	2.7	3.9	4.3	2.8	4.4
Arm fat-free mass (right)	2.8	14.2	21.3	1.6	4.2	2.5	4.3	4.3	3.7	3.8	3.2	4.4	3.6	4.4	4.0	4.6	3.1	3.5	4.3	2.8	3.4	4.5
Whole body water mass	2.8	16.0	23.4	1.7	4.4	2.8	4.7	4.3	3.9	4.2	3.4	4.5	3.7	4.8	4.2	4.8	3.3	3.7	4.5	3.1	3.7	4.7
Pulse rate	2.7	4.5	9.2	-0.3	-1.7	-2.1	-1.8	-2.5	-2.4	-2.6	-1.9	-1.9	-2.3	-1.7	-2.3	-2.4	-2.0	-1.8	-3.0	-1.8	-1.6	-2.8
Arm predicted mass (right)	2.7	13.8	21.2	1.6	4.1	2.5	4.2	4.2	3.6	3.7	3.2	4.3	3.4	4.3	3.9	4.6	3.1	3.5	4.3	2.8	3.3	4.4
Medication: Aspirin	2.7	3.5	7.8	0.4	1.6	0.7	2.2	1.0	2.1	1.8	2.8	2.0	1.7	2.5	2.0	1.5	2.4	2.5	1.7	-0.4	1.1	2.4
Cholesterol lowering medication	2.7	4.0	8.1	2.3	2.6	0.1	1.5	2.0	2.4	1.8	2.0	2.9	2.2	1.7	1.5	2.8	1.6	2.3	1.6	0.8	1.7	2.2
Height	2.6	50.1	97.8	5.6	8.3	6.9	8.9	6.3	3.7	7.9	5.9	7.4	3.8	9.4	8.5	6.9	7.9	7.4	4.3	5.7	9.9	5.6
Leg fat-free mass (left)	2.6	13.6	21.3	1.1	3.8	2.4	4.3	4.1	3.9	3.7	3.3	4.0	3.7	4.3	3.9	4.4	3.0	3.4	4.3	2.9	2.9	4.6
Whole body fat-free mass	2.6	15.1	22.4	1.6	4.2	2.6	4.6	4.2	3.9	4.0	3.3	4.4	3.7	4.7	4.1	4.6	3.2	3.6	4.4	3.0	3.5	4.6
Supplements: Fish oil (including cod liver oil)	2.6	3.4	6.1	0.3	1.9	0.8	2.0	2.0	2.1	2.4	1.7	2.5	2.5	1.6	1.8	2.3	1.3	2.1	1.9	0.6	1.5	2.1
Arm fat-free mass (left)	2.6	13.4	19.4	1.7	4.0	2.8	4.3	4.1	3.3	3.7	3.0	4.3	3.2	4.4	3.8	4.4	3.1	3.3	4.1	3.1	3.4	4.3
Leg predicted mass (left)	2.5	13.3	20.7	1.0	3.8	2.3	4.3	4.0	3.9	3.7	3.3	4.0	3.7	4.4	3.9	4.4	2.9	3.4	4.3	2.8	2.8	4.5
Trunk fat mass	2.5	10.7	23.3	1.2	3.2	1.9	3.1	4.8	3.2	3.3	2.1	3.7	3.2	3.2	3.1	4.3	2.2	2.5	3.3	4.6	2.5	4.1
High blood pressure (siblings)	2.5	3.6	8.1	1.3	2.1	-0.6	1.3	1.6	2.5	1.2	2.8	2.2	2.1	2.0	2.0	2.0	2.3	2.6	1.3	-0.7	1.2	2.2
Suffer from ‘nerves’	2.5	3.9	11.7	3.4	2.9	-1.2	0.8	1.6	2.8	1.7	1.9	2.4	2.7	1.1	0.9	2.5	1.3	1.8	1.6	-0.0	1.9	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.5	3.0	4.9	-1.0	-1.9	-0.8	-1.9	-1.6	-1.7	-1.7	-2.1	-2.1	-1.1	-2.0	-2.2	-2.0	-1.8	-2.1	-1.5	-0.6	-1.3	-2.0
Arm predicted mass (left)	2.5	12.8	19.4	1.8	3.9	2.9	4.0	4.2	3.2	3.5	2.8	4.3	3.0	4.2	3.6	4.4	3.0	3.1	4.0	3.4	3.4	4.2
Medication: Levothyroxine sodium	2.4	4.1	11.5	2.1	2.6	1.3	1.3	3.4	1.4	1.4	1.2	2.5	1.9	1.5	1.7	2.8	1.8	1.5	2.1	2.2	2.2	2.0
Trunk fat-free mass	2.4	13.6	21.9	2.0	4.3	2.6	4.5	3.8	3.4	3.9	3.0	4.3	3.3	4.7	3.9	4.2	3.1	3.5	3.9	2.8	3.8	4.1
Trunk predicted mass	2.4	14.0	22.2	2.1	4.3	2.6	4.5	3.8	3.5	3.9	3.1	4.4	3.3	4.7	3.9	4.3	3.2	3.5	4.0	2.7	3.8	4.2
Respiratory disease	2.3	5.2	12.6	1.1	2.4	1.8	2.8	1.5	1.5	2.2	2.8	2.1	2.2	2.8	2.6	1.8	3.6	3.2	1.5	-0.1	3.0	1.2
Comparative height size at age 10	2.3	12.7	23.2	3.2	4.3	2.4	3.9	2.9	3.2	4.0	3.2	3.5	3.4	4.2	4.1	3.7	3.7	3.9	2.7	2.8	4.8	2.6
Medication: Omeprazole (e.g. Zanprol)	2.3	2.8	5.6	0.5	1.9	-0.4	1.4	1.7	2.4	1.8	1.6	1.7	2.3	1.9	1.6	1.8	1.2	1.4	2.1	-0.0	1.2	2.3
Worry (Nagel 2018)	2.2	4.7	17.3	4.2	3.0	-0.5	0.3	2.3	2.4	1.1	2.5	2.6	2.4	0.8	0.7	2.8	2.4	1.8	2.3	-0.3	1.8	2.0
Systolic Blood Pressure	2.2	11.1	21.5	0.3	3.1	2.6	4.6	1.9	2.8	3.4	4.3	3.1	3.0	4.5	4.0	2.8	4.4	4.0	4.0	-0.6	2.8	3.3
Financial difficulties in last 2 years	2.2	3.0	5.2	-1.5	-2.2	0.6	-1.3	-1.8	-2.0	-1.7	-1.7	-2.3	-2.1	-1.8	-1.7	-2.2	-1.4	-2.2	-0.9	-0.2	-1.7	-1.8
Diabetes (self-reported)	2.2	3.4	10.8	1.2	1.7	2.1	0.6	3.1	0.9	2.0	0.8	1.8	1.0	1.0	1.6	2.3	1.7	0.6	2.4	3.3	2.0	2.2
Mean Putamen Volume	2.1	2.4	5.6	-1.6	-1.7	-0.6	-1.9	-0.1	-1.6	-0.9	-2.2	-1.5	-2.4	-1.8	-1.4	-1.3	-1.8	-2.0	-1.6	0.8	-1.4	-0.7
Age at last live birth	2.1	3.0	7.9	-0.5	-1.4	-1.8	-1.1	-2.7	-1.3	-2.0	-0.9	-2.2	-1.0	-1.2	-1.2	-2.3	-1.4	-1.3	-1.9	-2.8	-1.4	-2.1
Mineral and other dietary supplements	2.1	2.9	5.9	0.1	-1.7	-1.1	-2.1	-2.0	-1.5	-2.4	-1.2	-2.2	-1.6	-1.7	-1.6	-2.1	-1.1	-1.8	-1.5	-1.2	-1.7	-1.9
Ever taken oral contraceptive pill	2.1	2.3	4.8	-0.4	-1.4	-1.4	-1.7	-1.1	-1.4	-1.1	-2.2	-1.1	-1.7	-1.8	-1.8	-1.5	-2.2	-2.0	-1.7	0.2	-1.5	-0.9
Sitting height	2.0	14.1	30.0	2.4	4.2	3.7	5.5	3.0	2.1	4.2	2.9	3.7	1.9	5.3	5.0	3.8	3.7	3.9	2.4	3.1	4.7	3.1
Number of full brothers	2.0	2.5	6.0	0.4	1.5	1.4	1.2	2.0	1.3	0.8	2.1	2.2	1.1	1.1	1.5	2.4	1.8	1.4	2.2	0.4	0.6	2.4
Whole body fat mass	2.0	8.2	19.3	0.7	2.7	1.5	2.6	4.4	3.0	2.9	1.7	3.3	2.9	2.7	2.6	3.9	1.7	2.0	3.1	4.1	1.9	3.8
Financial situation satisfaction	2.0	2.5	4.5	-1.9	-2.0	-0.2	-1.3	-1.8	-1.5	-1.5	-1.0	-2.0	-1.9	-1.5	-1.3	-1.9	-1.3	-2.1	-0.5	-1.3	-2.1	-0.7
Commuting to job workplace: Cycle	2.0	2.4	8.9	-1.4	-1.9	0.6	-1.5	-0.7	-2.6	-1.2	-1.7	-1.6	-3.0	-1.2	-1.0	-1.6	-0.9	-2.1	-1.5	0.8	-1.1	-0.8
Neuroticism (Nagel 2018)	1.9	4.5	10.0	2.7	2.7	-1.3	0.7	2.7	3.0	1.2	2.4	2.5	3.2	1.1	1.0	2.9	1.8	1.8	2.2	-0.5	1.0	2.6
Taking other prescription medications	1.8	2.8	4.8	0.9	2.1	0.0	1.3	2.2	1.9	1.2	1.9	1.9	2.0	1.7	1.5	2.1	1.9	1.8	1.5	0.1	1.3	2.2
Number of full sisters	1.8	2.2	5.6	-0.3	-1.3	-0.3	-2.2	0.4	-2.2	-2.4	-1.9	-0.3	-2.2	-1.8	-1.6	-0.8	-1.4	-1.6	-1.3	0.5	-1.5	-0.6
Diabetes diagnosed by doctor	1.8	3.0	9.6	1.0	1.5	2.0	0.5	2.9	1.0	1.7	0.7	1.7	1.1	0.9	1.3	2.3	1.4	0.6	2.4	3.1	1.6	2.1
Depressed Affect (Nagel 2018)	1.7	3.6	9.6	0.7	1.8	-1.1	1.2	2.2	3.1	1.1	2.3	2.0	3.1	1.3	1.1	2.5	1.3	1.6	2.3	-0.9	-0.1	2.9
Medication: Cholesterol lowering	1.7	2.7	6.0	0.2	1.3	0.9	1.9	1.0	1.9	1.5	2.4	1.6	1.9	1.8	1.7	1.5	2.0	2.2	2.0	-0.5	0.8	2.0
Arm fat mass (left)	1.7	7.0	17.7	0.5	2.4	1.3	2.3	4.2	2.9	2.5	1.3	3.1	2.9	2.3	2.1	3.6	1.3	1.6	3.0	4.0	1.6	3.6
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	5.4	1.8	1.9	1.0	0.9	2.2	1.6	0.9	1.5	2.0	1.8	1.3	0.9	1.9	1.6	1.0	2.3	0.9	1.3	2.3
Glaucoma (self-reported)	1.6	1.9	4.0	1.1	1.5	1.2	0.2	2.0	1.4	1.4	1.0	1.5	1.4	0.4	0.7	1.9	1.2	0.8	1.9	1.8	1.3	1.8
Pain type(s) experienced in last month: Hip pain	1.6	2.1	4.2	0.3	1.3	0.4	1.0	1.6	1.8	1.4	2.1	1.5	1.7	1.2	1.7	1.6	1.7	1.6	1.4	0.2	0.9	2.0
Medication: Bendroflumethiazide	1.6	2.5	6.0	1.7	1.9	-0.6	1.5	0.9	2.2	1.0	1.8	2.0	2.4	1.7	1.4	1.9	1.1	1.9	1.2	0.0	0.8	1.8
Systolic blood pressure, automated reading	1.5	4.3	8.0	0.2	1.9	1.3	2.7	1.6	1.9	1.9	2.5	2.2	2.2	2.7	2.3	1.9	2.7	2.8	2.5	-0.3	1.8	1.8
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	8.6	-0.3	0.7	1.1	-0.3	2.9	0.6	0.7	-0.0	1.3	1.0	-0.1	-0.2	1.7	0.1	-0.6	2.3	2.0	0.3	2.0
Trunk fat percentage	1.5	5.8	17.0	0.7	2.1	1.3	2.0	4.1	2.3	2.4	1.2	2.7	2.3	2.1	2.2	3.4	1.4	1.6	2.3	4.1	1.6	3.0
Hayfever, allergic rhinitis or eczema	1.5	3.2	12.7	-3.2	-0.5	-0.4	2.1	-2.7	-0.4	-0.3	1.4	-0.6	0.3	1.6	1.0	-1.7	1.2	2.5	-1.8	-3.6	0.6	-2.4
Waist circumference	1.5	5.5	13.1	1.0	2.3	1.5	1.8	3.6	2.3	2.1	1.8	2.8	2.2	2.1	2.0	3.2	1.8	1.6	2.8	2.9	1.5	3.3
Father’s age at death	1.5	2.0	4.6	0.0	-1.0	-0.3	-1.9	-0.6	-1.8	-1.2	-2.1	-1.0	-1.9	-2.1	-1.8	-1.1	-1.6	-2.1	-0.7	-0.1	-0.9	-1.3
Medication: Lansoprazole	1.5	1.7	2.9	0.7	1.5	0.5	1.6	0.8	1.0	1.2	1.7	1.7	0.9	1.6	1.6	1.6	1.4	1.4	0.8	0.3	1.1	1.6
Shortness of breath walking on level ground	1.5	1.8	5.0	0.3	0.9	1.9	0.7	2.2	0.6	1.7	1.0	1.2	0.8	0.8	1.2	1.5	1.6	0.9	1.8	1.7	0.8	1.9
Knee pain experienced in last month	1.5	2.3	6.0	0.7	1.3	1.0	0.6	2.5	1.7	1.8	1.0	1.8	1.6	0.3	1.0	2.4	1.0	1.3	2.1	1.4	0.8	1.9
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	7.5	2.7	1.9	1.7	1.5	1.6	0.4	1.5	1.2	1.7	0.2	1.4	1.3	1.7	1.8	1.1	0.9	1.7	1.8	1.5
Asthma (self-reported)	1.5	2.9	8.6	0.3	1.7	0.1	2.4	0.6	1.5	1.5	2.3	1.5	1.8	2.4	2.1	1.0	2.4	2.9	0.4	-1.0	1.9	0.7
Reaction Time	1.4	2.6	4.8	-2.1	-2.0	-1.0	-1.6	-1.7	-0.8	-1.0	-1.8	-2.2	-0.7	-2.0	-1.8	-1.7	-2.2	-1.7	-1.1	-0.5	-1.8	-1.5
Prostate Cancer	1.4	2.0	4.0	-1.4	-1.5	-0.4	-1.2	-1.2	-1.9	-1.7	-1.7	-1.8	-1.6	-0.7	-1.0	-2.0	-1.2	-1.4	-1.8	-0.3	-0.5	-1.6
Type 2 Diabetes (T2D) (2018)	1.4	2.5	9.3	1.0	1.4	2.0	0.6	2.6	0.7	1.6	0.7	1.5	0.9	0.9	1.3	2.1	1.4	0.4	1.8	3.1	1.5	2.0
Lung FVC	1.4	7.3	15.8	-1.3	-2.7	-0.4	-3.5	-0.7	-3.5	-2.4	-4.0	-1.8	-3.5	-3.8	-3.3	-1.9	-3.3	-3.5	-2.0	0.9	-2.2	-2.1
Average weekly fortified wine intake	1.4	1.6	3.0	1.6	1.7	0.5	1.5	0.7	1.1	1.3	1.3	1.4	0.7	1.7	1.4	1.5	1.3	1.5	0.7	0.6	1.6	0.9
Asthma	1.4	2.9	8.9	0.4	1.7	0.0	2.2	0.6	1.6	1.5	2.3	1.6	2.0	2.3	2.0	1.0	2.4	3.0	0.3	-0.9	1.9	0.6
Birth weight of first child	1.4	2.5	4.7	-2.1	-1.8	-1.4	-1.0	-1.9	-1.3	-1.4	-1.1	-2.2	-1.3	-0.9	-1.1	-2.1	-1.6	-1.4	-1.9	-1.6	-1.4	-1.8
Peak expiratory flow (PEF)	1.4	3.2	6.9	1.2	2.0	0.9	2.6	0.8	1.8	1.6	2.1	1.8	1.8	2.6	2.2	1.6	1.8	1.9	1.7	0.3	1.6	2.0
Ever highly irritable/argumentative for 2 days	1.4	1.7	3.6	0.8	1.1	1.9	1.1	1.4	1.0	1.5	1.4	1.1	0.9	0.8	1.1	1.6	1.6	0.9	1.7	1.5	0.9	1.7
Chronic bronchitis/emphysema (mother)	1.4	1.6	4.0	0.6	-1.1	-1.1	-1.7	-0.9	-1.3	-1.5	-1.3	-1.0	-1.5	-1.4	-1.5	-1.1	-1.0	-1.2	-2.0	0.0	-0.9	-1.6
Medication for pain relief, constipation, heartburn	1.4	2.4	7.2	-0.8	-1.5	0.8	-1.4	-0.5	-2.7	-1.6	-2.1	-1.2	-2.5	-1.5	-1.4	-1.3	-1.5	-2.2	-1.5	1.3	-0.8	-1.1
Pulse rate, automated reading	1.4	4.6	8.2	-0.2	-1.7	-2.8	-2.3	-2.5	-1.9	-2.4	-1.3	-2.0	-1.9	-2.4	-2.2	-2.0	-1.9	-1.6	-2.5	-2.9	-2.1	-2.6
Depression (Nagel 2018)	1.3	2.0	5.4	1.6	1.8	-0.3	-0.1	2.3	2.0	0.9	0.7	1.6	1.8	0.6	0.5	1.9	0.8	0.5	1.7	1.4	1.3	1.9
Intelligence (Savage-Jansen 2018)	1.3	4.1	10.2	-0.9	-2.1	-0.6	-1.3	-2.5	-2.5	-1.9	-2.3	-1.9	-3.0	-1.1	-1.6	-2.8	-1.7	-1.5	-3.0	0.1	-0.8	-3.2
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.4	1.4	1.4	-0.7	1.3	0.4	1.6	0.2	1.8	0.9	1.9	1.7	1.3	1.1	1.2	1.3	0.9	-1.3	0.3	1.2
Hair/balding pattern: Pattern 2	1.3	1.7	4.7	1.1	-1.0	-0.7	-1.5	-1.0	-1.8	-2.0	-0.8	-0.9	-2.1	-1.2	-1.0	-1.2	-0.4	-0.9	-2.2	-0.1	-0.8	-1.6
Qualifications: None of the above	1.3	2.9	8.4	0.1	1.5	-0.4	0.3	2.5	2.8	1.3	1.4	2.1	2.9	0.6	0.6	2.5	0.8	1.6	2.5	0.4	0.6	2.1
Worrier / anxious feelings	1.3	2.5	7.4	2.7	2.0	-0.8	0.3	1.1	2.0	0.5	2.4	1.9	2.0	0.5	0.6	1.9	2.0	1.7	1.5	-1.2	0.8	1.2
Arm fat mass (right)	1.3	5.3	13.7	0.2	2.0	1.0	1.9	3.7	2.6	2.2	1.1	2.6	2.6	2.0	1.8	3.2	0.9	1.3	2.6	3.7	1.2	3.2
Migraine (self-reported)	1.3	1.6	4.9	1.6	1.8	0.6	0.7	1.7	0.9	0.5	1.2	1.9	0.5	1.0	0.9	1.9	0.9	0.5	1.5	0.4	0.8	2.2
Average weekly champagne plus white wine intake	1.3	1.8	4.9	-0.5	-1.6	-0.4	-0.8	-2.2	-1.6	-1.2	-0.8	-1.6	-2.0	-1.0	-0.7	-1.7	-0.7	-0.9	-2.0	-1.0	-1.2	-1.8
Pain experienced in last month	1.3	2.2	7.9	-0.2	-1.0	-0.1	0.1	-2.1	-2.3	-0.9	-1.3	-1.5	-2.5	0.4	-0.4	-2.3	-0.6	-0.7	-2.8	-0.1	0.4	-2.2
Leg fat mass (left)	1.3	5.1	14.5	0.4	2.1	0.8	1.7	3.8	2.5	1.9	1.2	2.7	2.4	1.9	1.8	3.3	1.1	1.4	2.6	3.2	1.1	3.2
Bipolar Disorder or Schizophrenia	1.2	2.9	6.2	-1.7	-2.1	-1.4	-1.4	-1.2	-1.9	-1.9	-1.6	-1.5	-1.8	-1.6	-2.0	-1.7	-1.8	-2.0	-1.1	-1.9	-2.5	-1.0
Bipolar Disorder (2011)	1.2	1.2	3.1	-0.6	-1.3	-0.0	-0.5	-1.1	-1.3	-0.8	-1.4	-0.8	-1.1	-1.4	-1.3	-0.7	-1.5	-0.8	-1.1	0.3	-1.2	-1.7
Allergy or Eczema	1.2	3.3	11.8	-2.4	0.1	-0.6	2.0	-2.7	-0.4	-0.1	1.1	-0.3	0.7	1.5	0.8	-1.6	1.1	2.6	-2.3	-3.4	1.6	-3.1
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.8	5.0	1.0	1.6	2.1	1.7	1.9	0.6	1.6	1.7	1.7	0.3	1.8	2.2	1.8	2.2	1.2	1.1	1.9	1.6	2.2
Medication: Ramipril	1.2	1.6	3.3	-0.8	0.9	-0.4	1.7	0.8	1.8	1.8	1.4	1.2	1.6	1.6	1.6	1.1	0.8	1.6	0.8	0.1	0.5	1.6
Medication: Simvastatin	1.2	1.8	4.5	0.5	1.2	0.4	1.5	0.6	1.8	1.3	1.9	1.4	1.9	1.4	1.2	1.1	1.6	2.1	1.4	-0.2	1.0	1.2
Had major operations	1.2	1.4	3.5	-0.9	0.7	0.6	1.4	0.7	1.7	1.8	1.2	0.9	1.5	1.5	1.0	1.0	0.6	1.0	1.3	0.4	0.6	1.9
Supplements: Vitamin C	1.2	1.4	3.2	0.6	1.0	1.0	1.7	0.6	0.8	0.7	1.8	1.2	1.0	1.4	1.2	1.1	1.7	1.7	1.3	-0.9	0.9	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	4.7	-1.8	-1.6	-1.2	-1.0	-1.3	-1.7	-2.1	-2.0	-1.5	-1.5	-0.8	-1.6	-2.0	-2.2	-1.9	-1.6	-0.5	-1.4	-1.1
Alcohol drinker status: Never	1.2	1.5	3.3	0.7	1.3	0.5	0.9	1.8	1.7	1.2	0.6	1.6	1.2	0.8	0.7	1.7	0.5	0.9	1.8	1.4	0.8	1.4
Number of operations (self-reported)	1.2	1.8	2.9	1.3	1.3	1.3	1.7	1.1	1.2	1.7	1.0	1.3	1.3	1.6	1.2	1.3	1.2	1.2	1.2	1.6	1.5	1.4
Schizophrenia (2018)	1.1	2.2	6.2	-1.8	-1.7	-1.6	-0.9	-1.2	-1.0	-1.5	-1.2	-1.3	-1.3	-1.2	-1.6	-1.3	-1.8	-1.7	-0.6	-2.0	-2.5	-0.3
Ovarian Cancer	1.1	1.5	3.2	1.1	1.8	0.7	1.4	0.9	0.9	0.9	1.1	1.6	0.9	1.5	1.3	1.4	1.2	1.3	0.3	0.8	1.6	1.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	4.2	0.1	0.9	1.7	1.2	1.3	0.9	1.3	1.4	1.0	1.5	0.8	0.7	1.3	1.4	0.4	2.1	0.6	0.6	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	4.6	1.2	1.5	-0.1	-0.0	1.3	1.9	0.8	1.1	1.2	2.1	0.2	0.4	1.7	0.8	0.7	1.7	0.5	0.7	1.8
Number of incorrect matches in round	1.1	1.8	3.8	1.6	1.6	0.9	0.8	1.8	0.9	1.5	0.7	1.7	0.7	1.3	0.9	1.5	1.2	0.9	1.0	2.0	1.8	1.2
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	4.1	2.0	1.4	-0.2	-0.4	1.7	1.8	0.5	1.6	1.4	1.7	-0.1	0.5	1.7	1.5	1.4	1.3	0.1	0.7	1.2
Qualifications: A levels/AS levels or equivalent	1.1	2.4	9.1	-0.7	-1.5	0.9	-1.0	-1.1	-3.0	-1.2	-1.9	-1.4	-3.0	-1.1	-0.8	-1.8	-0.9	-1.3	-2.0	0.2	-0.1	-2.0
Body fat percentage	1.1	4.5	13.8	0.4	1.8	0.8	1.5	3.7	2.2	1.9	0.9	2.4	2.2	1.6	1.7	3.0	0.9	1.2	2.1	3.7	1.1	2.8
Age at first live birth	1.1	2.0	6.2	-1.2	-1.0	-2.3	-0.4	-2.5	-0.4	-0.9	-0.5	-1.9	-0.4	-0.5	-0.4	-1.9	-1.3	-0.7	-1.9	-2.5	-1.1	-1.5
Medication: Omeprazole	1.1	1.3	3.3	0.1	1.2	-0.7	0.7	1.6	1.6	1.2	0.8	1.1	1.6	1.3	1.0	1.3	0.6	0.8	1.6	-0.1	0.6	1.8
Leg fat mass (right)	1.1	4.1	11.3	0.3	1.9	0.6	1.5	3.4	2.4	1.7	1.1	2.4	2.2	1.7	1.5	2.9	0.8	1.2	2.4	2.9	0.9	3.0
Alcohol intake frequency.	1.1	2.6	8.3	-0.3	1.0	-0.2	0.1	2.7	2.7	0.7	1.3	1.4	2.4	0.3	0.6	2.2	0.8	0.5	2.9	0.6	-0.5	2.8
High cholesterol (Self-reported)	1.1	2.0	4.0	1.8	1.6	1.1	1.1	0.9	1.4	1.2	1.9	1.6	1.4	1.1	1.1	1.6	2.0	2.0	1.2	0.4	1.4	1.1
Medication: Lisinopril	1.1	1.4	4.9	0.7	1.0	0.4	0.5	1.2	1.3	0.9	1.5	1.3	1.4	0.7	0.9	1.3	1.4	1.1	2.2	-0.6	0.3	1.6
Medication: Atorvastatin	1.1	1.4	3.0	0.7	1.1	0.7	0.8	1.3	1.2	0.8	1.7	1.6	1.1	0.7	0.9	1.6	1.5	1.4	1.3	-0.0	0.4	1.7
Major Depression (MDD)	1.0	1.2	3.1	0.6	1.0	0.1	0.7	1.3	1.6	1.8	0.8	1.0	1.3	0.8	1.1	1.4	0.6	0.8	1.3	0.9	0.8	1.4
Body Mass Index (BMI) (2010)	1.0	1.4	5.7	-0.4	-0.9	-1.3	-2.3	0.8	-0.4	-0.8	-1.4	-0.3	-0.6	-2.4	-1.7	-0.1	-1.5	-1.5	-0.6	0.4	-1.2	-0.2
HbA1C	1.0	1.1	3.9	-1.1	-0.8	-2.0	-1.6	-0.3	-0.2	-0.9	-1.1	-0.9	-0.6	-1.4	-0.7	-0.6	-1.7	-0.9	-1.0	-0.9	-1.3	-0.1
Past tobacco smoking	1.0	1.8	5.2	0.4	1.5	1.3	1.0	1.9	1.3	0.9	1.1	1.4	1.6	1.3	0.8	1.4	1.3	0.6	2.3	1.4	1.5	1.2
Nervous feelings	1.0	1.8	10.8	3.3	1.9	-0.4	-0.2	1.2	0.9	0.7	1.6	1.8	1.1	0.1	0.1	1.5	1.8	1.2	0.5	-0.7	1.3	0.7
Allergy	1.0	2.2	7.8	2.1	-0.3	0.6	-2.1	1.2	-0.6	-0.1	-1.8	-0.4	-1.3	-1.8	-1.3	0.5	-1.7	-2.7	0.7	2.8	-0.8	1.3
Fluid intelligence score	1.0	2.1	5.0	-1.3	-1.7	-0.8	-0.7	-1.9	-1.4	-1.1	-1.7	-1.8	-1.6	-1.1	-1.1	-2.0	-1.5	-1.0	-1.8	-0.5	-1.0	-2.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	3.1	-0.1	-1.0	-0.6	-1.3	-0.6	-1.4	-1.7	-1.2	-1.1	-1.0	-0.9	-0.7	-1.3	-0.7	-0.9	-1.7	0.2	-0.5	-1.8
Arm fat percentage (left)	1.0	3.9	12.0	-0.2	1.4	0.6	1.4	3.5	2.5	1.8	0.8	2.1	2.4	1.3	1.3	2.8	0.5	1.0	2.3	3.3	0.5	2.9
Mood swings	1.0	1.9	4.7	1.2	1.3	-1.5	0.7	0.8	2.2	-0.5	2.0	1.3	2.2	0.8	0.4	1.5	1.0	1.0	1.5	-1.8	-0.7	1.6
Osteoporosis (self-reported)	1.0	1.3	4.9	1.4	1.1	1.8	0.1	1.4	-0.3	0.7	0.7	1.2	0.2	0.4	0.9	0.7	1.7	1.1	0.0	1.6	2.2	0.3
Heel T-Score	0.9	7.5	14.6	1.9	2.8	3.8	2.7	3.6	0.2	2.4	2.4	2.9	0.3	3.1	3.2	2.7	3.8	1.7	2.5	2.4	2.8	3.4
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.6	0.9	1.5	1.7	1.6	1.6	0.3	1.4	1.3	1.3	0.2	1.9	2.1	1.4	2.0	1.1	0.4	2.0	1.6	1.6
Neuroticism score	0.9	1.9	4.4	2.1	1.7	-1.3	0.4	1.1	1.8	0.2	2.0	1.6	1.8	0.6	0.3	1.7	1.3	1.2	1.3	-1.5	0.1	1.5
Alcohol intake versus 10 years previously	0.9	1.3	4.2	0.6	1.3	1.0	0.5	1.8	0.9	0.5	1.1	1.3	1.3	0.5	0.6	1.7	1.1	0.3	2.0	0.2	0.6	1.8
Medication: Seretide 50 evohaler	0.9	1.1	5.2	2.3	1.5	0.4	0.4	1.2	-0.0	0.4	0.0	1.4	0.7	0.7	0.4	1.0	1.0	0.8	-0.4	1.6	1.8	0.2
Mean time to correctly identify matches	0.9	1.7	3.8	-1.8	-1.6	-0.9	-1.6	-0.5	-0.6	-0.6	-1.8	-1.7	-0.7	-1.7	-1.4	-1.0	-2.0	-1.7	-0.9	0.5	-1.3	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.9	2.0	5.0	0.2	1.4	1.5	2.1	0.5	0.7	1.8	1.4	1.1	0.5	2.2	2.2	1.0	1.5	1.4	1.0	0.3	1.8	1.5
Heart disease (siblings)	0.9	1.1	3.0	1.7	1.2	0.3	0.3	1.4	0.9	0.6	0.7	1.3	1.5	0.2	0.5	1.3	1.1	0.9	0.3	1.6	1.2	0.3
HDL Cholesterol	0.8	1.4	3.0	-1.2	0.6	1.3	1.6	0.7	0.9	0.8	1.5	0.6	1.4	1.7	1.4	0.4	1.5	1.2	1.7	-0.5	0.7	1.0
Rheumatoid Arthritis	0.8	1.1	4.1	0.1	1.0	-1.0	-0.3	1.7	1.8	0.7	0.5	0.8	1.7	0.2	0.1	1.1	-0.0	-0.4	2.0	-0.1	0.0	1.6
Supplements: Zinc	0.8	0.9	2.6	-0.3	0.7	0.9	1.2	0.6	0.9	0.8	1.3	0.9	0.9	0.9	0.7	0.8	0.8	1.0	1.6	-0.3	0.4	1.4
Fed-up feelings	0.8	1.4	4.0	0.3	0.9	-0.7	0.9	0.3	1.9	0.2	1.6	1.0	2.0	0.6	0.2	1.3	0.5	0.9	1.8	-1.6	-0.8	1.8
Hair/balding pattern: Pattern 3	0.8	1.1	4.8	0.1	0.7	-0.4	0.6	0.7	2.0	1.1	1.1	1.1	2.2	0.3	0.4	1.4	0.3	1.1	1.7	-0.5	-0.1	0.9
Happiness	0.8	0.9	2.4	-0.0	-1.0	-0.6	-1.1	-0.8	-1.1	-1.6	-0.3	-0.8	-1.1	-1.0	-1.0	-0.9	-0.6	-1.2	-0.6	-1.4	-1.5	-0.0
Hair/balding pattern: Pattern 4	0.8	1.9	10.3	-0.3	1.1	0.7	1.0	2.1	0.9	2.4	-0.8	0.7	0.9	0.9	1.1	1.5	-0.3	0.2	0.4	3.2	1.6	1.5
Qualifications: College or University degree	0.8	2.6	8.3	1.0	-0.7	1.7	0.3	-1.7	-2.9	-0.5	-1.7	-1.3	-2.6	-0.0	-0.1	-1.9	0.2	-0.2	-2.6	1.3	1.4	-2.6
Eye problems/disorders: None of the above	0.8	0.9	5.8	0.9	-0.5	1.7	0.4	-1.0	-1.7	-0.2	-0.4	-0.4	-2.4	0.2	0.4	-0.5	0.5	-0.1	-1.0	0.7	0.3	-1.0
Handedness (chirality/laterality): Left-handed	0.8	1.0	4.0	-1.2	-1.2	-0.1	-0.6	-1.0	-0.3	-0.6	-0.1	-0.4	-0.8	-1.5	-1.4	-0.5	-0.9	-0.6	0.7	-1.7	-2.0	-0.4
Friendships satisfaction	0.8	1.0	2.4	0.6	-1.0	-0.4	-1.3	-0.6	-1.5	-1.5	-0.9	-0.6	-1.4	-1.0	-1.1	-1.3	-0.5	-0.8	-1.0	-0.4	-0.7	-1.2
Eye problems/disorders: Cataract	0.8	0.9	1.6	-1.2	-1.0	-1.3	-0.7	-1.0	-0.2	-1.0	-0.7	-1.2	0.4	-0.8	-1.1	-1.1	-1.1	-0.5	-1.0	-1.2	-0.9	-1.0
Ever smoked	0.8	1.5	5.4	0.1	-1.3	-0.8	-1.0	-1.5	-1.5	-0.8	-1.1	-1.0	-1.8	-1.4	-0.7	-1.0	-1.1	-0.5	-2.3	-0.9	-1.3	-1.1
Bipolar Disorder (2018)	0.7	1.0	3.0	-0.4	-1.2	-0.1	-1.1	-0.4	-1.7	-1.4	-1.0	-0.8	-1.2	-1.0	-1.2	-1.1	-0.6	-1.0	-0.9	-0.5	-0.9	-1.3
Sensitivity / hurt feelings	0.7	1.1	5.4	2.3	1.1	-2.3	-0.4	0.0	1.6	-0.4	0.8	0.8	1.7	-0.2	-0.2	1.0	0.2	0.9	-0.2	-0.7	-0.1	-0.3
Relative age voice broke	0.7	1.1	3.8	1.4	-0.3	0.9	-0.4	-1.4	-1.9	-1.1	-0.3	-1.0	-1.5	-0.1	-0.3	-1.3	0.7	-0.5	-1.6	-0.3	0.6	-1.3
Alcohol usually taken with meals	0.7	1.1	6.1	-0.7	-0.1	2.5	0.1	1.5	-1.4	1.0	-0.5	0.1	-1.2	0.2	0.5	-0.0	0.7	-0.6	0.5	1.9	1.1	1.0
Arm fat percentage (right)	0.7	2.7	9.0	-0.2	1.1	0.5	1.0	2.9	2.1	1.5	0.6	1.7	2.0	1.1	1.0	2.4	0.3	0.6	2.0	3.0	0.3	2.5
Time employed in main current job	0.7	0.8	3.6	-0.4	-0.8	-1.9	-0.9	-0.4	-0.4	-1.0	-0.8	-1.0	-0.1	-0.6	-0.4	-1.1	-0.7	-0.2	-1.3	-0.9	-0.6	-1.3
Number of live births	0.7	1.0	2.1	-0.6	-1.1	0.3	-1.1	-0.6	-0.9	-0.8	-1.5	-0.9	-1.4	-1.4	-1.4	-0.9	-1.2	-1.3	0.0	0.5	-0.8	-1.0
Noisy workplace	0.7	0.8	2.8	1.7	1.2	0.1	0.3	0.9	0.8	0.4	1.2	1.2	0.8	0.8	0.4	1.2	0.9	0.8	0.8	-0.0	0.7	1.3
Length of working week for main job	0.7	0.8	2.1	-0.2	-0.9	-1.4	-1.3	-0.5	0.3	-1.1	-0.4	-0.9	0.3	-1.2	-1.1	-0.9	-0.8	-0.6	-0.1	-1.0	-1.3	-0.8
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.7	-0.8	-1.2	-0.3	-0.3	-1.6	-1.3	-0.6	-1.0	-1.5	-1.5	-0.5	-0.4	-1.4	-1.0	-0.8	-1.5	-0.9	-0.8	-1.2
Birth weight	0.7	1.4	11.8	-0.9	-0.0	-1.5	1.4	-1.5	1.2	0.1	1.1	-0.1	1.6	0.6	-0.2	-0.3	-0.4	0.5	0.8	-3.4	-1.2	0.1
Osteoarthritis (self-reported)	0.7	0.9	2.9	-1.3	-1.0	-1.7	-1.1	0.2	0.0	-0.8	-0.9	-0.3	-0.0	-1.2	-1.3	-0.4	-1.3	-0.7	-0.4	-0.6	-1.6	-0.4
Illnesses of father: High blood pressure	0.7	0.9	2.9	0.5	0.7	1.2	0.6	0.7	0.8	0.8	1.3	0.7	1.1	0.6	0.5	0.6	1.4	0.9	1.7	-0.6	0.5	1.5
Irritability	0.7	1.2	3.8	-0.2	-0.6	-2.0	-0.3	-1.3	-0.6	-1.3	-0.8	-1.0	-1.0	-0.3	-1.2	-1.2	-1.0	-0.8	-1.4	-1.8	-1.1	-1.0
Verbal and Numeric Reasoning (VNR)	0.6	1.3	3.8	0.1	-0.9	-0.9	-1.1	-1.4	-1.2	-0.9	-1.3	-1.0	-1.8	-1.1	-0.9	-1.4	-1.1	-0.7	-1.8	0.1	-0.3	-1.9
BMI	0.6	3.5	15.1	-0.6	0.8	-0.2	-0.1	3.9	2.2	1.5	-0.2	1.8	1.9	-0.1	0.2	2.6	-0.6	-0.3	2.6	3.2	-0.6	3.3
Neuroticism	0.6	1.4	4.0	2.0	1.4	-1.2	-0.1	1.5	1.5	0.2	1.2	1.5	1.6	0.0	-0.1	1.6	0.9	0.5	1.4	-0.6	-0.0	1.6
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.6	1.9	1.4	-0.7	-0.1	0.7	1.5	0.2	0.5	0.7	1.4	0.3	0.1	1.0	0.3	0.4	0.6	0.7	0.9	0.8
Angina	0.6	0.8	3.2	0.7	0.9	-0.3	0.5	0.4	1.5	0.4	1.2	1.0	1.8	0.4	0.4	1.2	0.5	0.7	0.9	0.0	-0.0	1.2
Current tobacco smoking	0.6	0.9	3.2	-0.5	-1.1	-0.3	-1.6	-0.1	-0.8	-1.3	-0.8	-0.3	-1.1	-1.8	-1.3	-0.2	-1.0	-0.9	-0.8	-0.0	-1.4	-0.3
Maternal smoking around birth	0.6	0.8	2.6	0.4	-0.8	-0.4	-0.5	-1.5	-0.7	-1.2	0.1	-1.0	-0.9	-0.6	-0.7	-1.2	-0.1	-0.4	-0.8	-1.6	-0.9	-1.3
Multivitamins +/- minerals	0.6	0.8	3.6	0.7	0.9	1.0	0.5	1.4	0.4	1.3	0.2	1.0	0.2	0.4	0.6	0.9	0.4	0.4	0.5	1.9	1.1	0.9
Exposure to tobacco smoke outside home	0.6	0.8	2.4	1.5	0.8	-0.0	0.4	0.7	1.4	1.2	1.0	0.9	1.1	0.4	0.7	1.1	0.8	1.0	0.5	1.1	0.4	0.7
Worry too long after embarrassment	0.6	1.1	2.6	1.5	1.2	0.6	0.4	1.4	0.7	0.9	1.2	1.3	0.8	0.8	0.8	0.9	1.6	0.7	1.1	0.7	1.0	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.1	0.4	0.8	0.1	0.6	1.4	1.2	1.3	0.3	0.5	1.2	0.7	0.7	0.7	0.5	0.6	0.5	1.4	0.7	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.5	0.7	-0.6	-0.4	-1.3	-0.4	-1.0	-0.9	-0.9	-0.4	-0.5	-1.0	-1.3	-1.0	-0.4	-0.6	-0.6	-0.3	-0.0	-1.6
Pulse wave peak to peak time	0.6	0.7	3.8	-0.1	0.0	1.7	0.5	0.7	0.2	1.3	-0.0	0.4	-0.4	0.0	0.7	0.7	0.3	-0.1	0.8	2.0	0.1	1.2
Family relationship satisfaction	0.6	0.7	2.4	1.6	0.9	-0.1	-0.4	1.1	0.5	-0.3	1.2	1.4	0.6	0.1	0.3	0.9	1.1	0.6	1.0	-0.4	0.2	0.9
Illnesses of father: Heart disease	0.6	0.9	5.0	0.3	-0.7	-1.0	-0.3	-1.2	-1.2	-1.0	0.0	-0.9	-1.0	-0.1	-0.3	-1.2	-0.1	-0.2	-2.2	-1.2	-0.6	-0.8
Medication: Gliclazide	0.6	0.7	3.6	-0.5	0.5	1.5	0.4	1.5	-0.4	0.9	-0.5	0.2	-0.5	0.3	0.6	0.9	0.2	-0.5	1.0	1.9	0.9	0.7
Illnesses of father: None of the above (group 1)	0.6	0.8	3.9	-2.0	-0.9	-1.2	0.2	-1.0	0.1	-0.4	-0.8	-0.7	-0.6	-0.3	-0.1	-0.3	-1.5	-0.4	-0.4	-0.9	-1.3	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	2.4	0.8	0.7	0.9	-0.1	1.1	0.9	1.1	0.6	0.8	0.9	-0.2	0.1	1.1	0.5	0.3	0.9	1.5	0.8	1.0
Leg fat percentage (left)	0.6	2.0	9.4	-0.0	1.0	0.0	0.4	3.1	1.4	0.7	0.1	1.7	1.5	0.6	0.6	2.2	0.1	0.4	1.6	2.6	0.2	2.1
Risk taking	0.6	0.9	1.9	-0.4	-1.1	-0.8	-0.9	-1.0	-0.6	-0.3	-1.3	-1.4	-0.8	-1.2	-1.1	-0.9	-1.3	-1.0	-1.0	-0.1	-1.3	-0.7
Diastolic blood pressure, automated reading	0.6	1.9	4.1	0.1	1.0	0.4	2.0	0.3	1.7	1.0	2.0	1.2	2.0	1.7	1.4	1.1	1.4	1.9	1.9	-0.9	0.5	0.9
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.9	-0.9	0.5	-0.4	1.2	0.2	1.4	0.5	1.2	0.6	1.3	1.0	1.0	0.5	0.7	1.3	0.6	-1.0	0.1	0.7
Alzheimer’s Disease (in mother)	0.5	0.6	1.4	0.2	1.0	-0.1	0.6	0.4	1.2	0.9	1.0	0.5	1.1	0.8	0.9	0.6	0.6	0.8	0.6	-0.3	0.9	0.9
Crohns Disease (2017)	0.5	1.2	5.0	-0.2	0.3	-2.2	-0.7	1.3	1.1	-0.2	-0.9	0.7	2.2	-0.8	-1.0	0.7	-1.6	-0.7	1.2	-0.6	-0.9	0.8
Irritable Bowel Disease (IBD)	0.5	1.3	4.0	-0.3	0.1	-1.6	-0.5	1.2	0.9	-0.6	-0.7	0.6	2.0	-1.1	-1.1	1.1	-1.5	-0.7	1.8	-1.3	-1.5	0.6
Coronary Artery Disease (CAD)	0.5	0.6	2.5	-1.6	-0.3	0.2	0.7	-0.2	1.1	0.7	1.0	-0.1	0.7	0.5	0.7	-0.2	0.6	0.8	1.0	-1.2	-0.1	-0.2
Fasting Glucose	0.5	0.6	2.4	-0.8	-0.6	-1.3	-0.4	-0.7	-0.3	-0.8	-1.1	-0.7	0.0	-0.5	-0.9	-0.5	-1.5	-0.9	-0.9	-0.6	-1.1	-0.4
Neuroticism (2016)	0.5	0.7	2.6	0.9	1.0	-1.6	-0.2	1.2	1.1	-0.3	0.5	1.1	0.8	0.1	-0.3	1.0	0.1	0.0	0.8	-0.6	-0.3	1.2
Ulcerative Colitis	0.5	0.8	4.0	-0.2	0.5	1.0	0.5	1.5	0.4	0.6	0.2	1.1	0.9	-0.0	-0.1	1.5	0.0	-0.2	2.0	-0.1	-0.3	1.4
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.3	-0.4	-0.7	0.3	-0.9	0.6	-1.5	-0.7	-0.8	-0.4	-1.0	-1.0	-1.1	-0.4	-0.3	-1.1	0.1	-0.4	-0.6	-0.3
Vitamin and mineral supplements	0.5	0.7	1.6	-0.3	-0.8	-1.0	-0.9	-0.9	-0.6	-1.0	-1.1	-1.3	-0.5	-0.5	-0.7	-1.0	-0.9	-1.1	-0.9	-0.3	-0.7	-1.0
Diabetes (father)	0.5	0.6	2.5	1.2	0.3	1.4	-0.6	1.1	-0.7	0.2	0.5	0.2	-0.6	-0.1	0.1	0.2	1.6	0.1	0.1	1.2	1.1	0.2
Impedance of leg (right)	0.5	2.6	8.8	0.6	-1.1	-0.4	-1.0	-2.3	-2.5	-1.1	-1.2	-1.6	-2.4	-1.0	-1.0	-2.0	-0.6	-0.8	-3.0	-1.1	0.0	-2.8
Serious illness, injury or assault to yourself	0.5	0.6	1.7	-0.3	0.7	0.1	0.5	1.0	1.0	1.0	0.0	0.7	1.2	0.7	0.5	0.8	-0.2	0.0	1.1	1.3	0.4	1.1
Body mass index (BMI)	0.5	2.3	8.9	-0.7	0.8	-0.1	0.5	3.0	2.0	0.9	0.4	1.7	1.9	0.6	0.6	2.2	-0.1	0.4	2.2	2.3	-0.3	2.5
Had other major operations	0.5	0.6	2.5	0.3	0.6	1.3	0.6	0.4	0.8	1.2	0.7	0.6	0.9	0.1	0.2	0.9	0.5	0.5	1.6	0.2	0.5	0.9
Heart attack	0.5	0.7	1.7	-0.8	0.4	-0.2	1.2	-0.0	1.2	0.4	1.2	0.5	1.2	1.0	0.9	0.4	0.8	1.3	0.6	-1.1	0.2	0.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	3.8	-0.5	-0.0	0.6	0.4	-0.7	-1.1	-0.9	0.0	0.2	-0.7	0.5	0.2	-0.7	0.7	0.9	-0.9	-0.7	1.0	-1.9
Depression (self-reported)	0.5	0.6	2.7	-0.7	-0.4	-1.0	0.5	-1.6	0.1	-0.4	-0.3	-0.8	-0.0	0.2	-0.4	-0.9	-1.0	-0.2	-0.9	-1.2	-0.6	-0.7
Tense / ‘highly strung’	0.5	0.9	5.0	2.2	1.0	-0.6	-0.6	0.5	0.9	0.2	1.5	0.6	0.2	-0.3	-0.1	0.9	1.4	0.8	0.7	-1.1	0.2	0.9
Comparative body size at age 10	0.5	1.5	4.7	-1.6	-0.4	-1.7	-0.2	0.3	1.6	0.1	0.1	0.0	1.8	-0.8	-0.9	0.6	-1.4	-0.7	1.6	-1.8	-2.2	1.6
Neck or shoulder pain in last month	0.5	0.7	2.4	0.1	0.6	0.8	0.1	1.1	1.1	0.5	0.9	0.7	1.5	0.2	0.3	0.9	0.8	0.2	1.6	0.5	0.4	1.2
Angina (self-reported)	0.5	0.6	3.1	0.3	0.6	-0.5	0.4	0.2	1.4	0.2	1.0	0.8	1.8	0.3	0.2	0.9	0.3	0.7	0.8	-0.3	-0.3	1.0
Leg pain on walking	0.5	0.7	2.2	-0.2	0.2	-1.3	-0.3	1.2	1.5	0.4	0.8	0.4	1.4	0.0	0.3	0.8	0.2	0.2	1.1	-0.4	-0.6	1.1
Smoking status: Previous	0.5	0.8	2.7	-0.7	-0.9	-1.5	-0.2	-1.6	-0.2	-0.1	-0.3	-1.1	-0.4	-0.3	0.0	-1.1	-0.8	0.1	-1.4	-1.6	-0.9	-0.7
Commuting to job workplace: Walk	0.5	0.5	2.4	-0.7	-1.0	0.5	-0.0	-1.6	-0.8	-1.1	0.2	-0.5	-0.6	-0.3	-0.6	-0.6	-0.3	-0.3	-0.4	-0.8	-1.0	-0.9
Back pain experienced in last month	0.5	0.7	3.0	-0.8	0.3	-0.4	-0.3	1.7	1.3	0.9	0.1	0.4	1.2	-0.4	0.1	1.0	-0.1	-0.3	1.4	0.7	-0.4	1.3
Smoking status: Current	0.5	0.9	3.4	-0.1	-0.9	0.1	-1.6	0.2	-1.0	-1.1	-0.8	-0.1	-1.2	-1.9	-1.3	0.0	-0.7	-0.8	-0.8	0.5	-1.1	-0.2
Wears glasses or contact lenses	0.5	0.6	3.2	-1.0	0.1	0.2	0.4	1.1	-0.2	1.1	-0.8	0.2	0.1	0.5	0.8	-0.2	-0.2	0.4	-0.8	1.8	1.1	-0.1
Age started oral contraceptive pill	0.5	0.6	2.2	1.2	1.1	0.3	-0.2	1.5	0.4	0.3	0.6	1.0	0.6	-0.0	0.3	1.1	0.9	0.4	1.2	0.2	0.8	0.7
Supplements: Calcium	0.5	0.5	1.8	-0.4	0.9	0.5	1.0	-0.2	0.7	1.3	0.6	0.3	0.9	1.1	0.9	0.3	0.3	0.4	0.5	0.1	1.2	0.6
Ulcerative Colitis (UC)	0.4	0.7	3.4	-0.4	-0.2	-0.4	-0.1	0.6	0.4	-0.7	0.0	0.4	1.0	-0.7	-0.8	0.8	-0.6	-0.4	1.8	-1.8	-1.4	0.3
Age at First Birth	0.4	0.6	2.2	0.4	-0.1	-0.1	-0.3	-0.8	-1.1	-0.6	-0.6	-0.7	-1.0	0.2	-0.3	-1.2	-0.4	-0.5	-1.5	0.3	1.0	-1.5
Triglycerides	0.4	0.6	1.5	0.7	-0.5	-0.3	-1.0	-1.1	-0.9	-0.7	-0.4	-0.3	-1.0	-1.2	-1.2	-0.6	-0.3	-0.3	-0.9	-0.6	-0.4	-1.1
Smoking Status	0.4	0.9	2.2	-1.2	-1.2	-1.1	-1.0	-1.0	-0.4	-0.6	-0.6	-0.7	-0.9	-1.3	-0.6	-0.4	-1.3	-0.4	-1.4	-0.7	-1.5	-0.2
Hand grip strength (left)	0.4	1.2	6.9	-0.6	-0.6	0.1	1.4	-2.6	-0.5	-0.5	0.5	-1.0	-0.1	0.7	-0.1	-1.4	0.2	0.6	-0.4	-2.3	-0.2	-1.7
Hearing difficulty/problems: Yes	0.4	0.6	4.0	0.3	0.6	-0.5	-0.2	0.6	1.6	0.7	0.5	0.4	2.0	0.1	0.5	0.6	0.0	0.7	0.6	0.9	0.6	0.4
Medication for hormone replacement therapy	0.4	0.4	2.8	-1.7	-0.6	-0.4	-0.3	-0.1	-0.1	-0.0	0.2	-0.3	-0.5	-0.2	-0.1	-0.2	-0.4	-0.3	0.2	-1.3	-1.0	1.1
Medication: Co-codamol	0.4	0.4	1.4	-0.5	-0.2	-1.2	-0.7	0.5	0.6	-0.2	-0.1	0.1	1.1	-1.1	-0.8	0.4	-0.4	0.0	0.3	-0.9	-1.0	0.6
Hand grip strength (right)	0.4	1.2	6.0	-0.1	-0.0	-0.8	1.7	-2.2	0.3	-0.3	1.1	-0.3	0.7	1.3	0.6	-0.8	0.4	1.4	-0.7	-2.4	-0.0	-1.1
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.9	-0.9	-0.7	-1.4	-0.3	-0.8	0.1	-0.2	0.1	-0.8	0.3	-0.1	-0.2	-0.9	-0.5	-0.3	-0.5	-1.7	-1.0	-0.0
Pain all over the body in last month	0.4	0.4	1.6	-1.3	0.4	-0.9	-0.1	0.4	1.0	0.3	0.2	0.2	1.0	0.1	-0.1	0.4	-0.5	-0.1	0.9	-1.0	-0.2	1.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	3.1	1.2	1.4	1.3	1.5	1.2	0.3	1.1	0.5	1.5	0.2	1.5	1.4	1.2	0.9	0.8	0.5	1.8	1.5	1.3
Prospective memory result	0.4	0.5	1.5	-0.6	-0.8	-1.1	-1.1	-0.3	0.1	-0.6	-0.6	-0.5	-0.1	-1.2	-1.1	-0.3	-0.8	-0.3	-0.3	-0.8	-1.2	-0.4
Breastfed as a baby	0.4	0.5	1.4	1.2	-0.0	0.7	-1.0	0.8	-1.2	-0.4	-0.4	-0.1	-0.8	-0.6	0.2	0.0	0.4	-0.6	-0.5	1.1	0.5	-0.0
Medication: Paracetamol	0.4	0.7	3.2	0.4	-0.1	-1.4	-0.2	-1.1	0.8	-0.4	0.7	-0.6	1.2	-0.3	-0.1	-0.4	0.3	0.8	-0.6	-1.8	-0.3	-1.1
Headache pain in last month	0.4	0.7	2.5	0.6	0.7	0.1	0.6	1.2	1.2	0.9	0.3	0.9	1.6	0.4	0.3	1.1	0.2	0.3	1.3	0.7	0.1	0.9
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.0	0.5	0.7	-0.8	0.4	0.4	1.1	0.5	0.1	0.4	1.7	0.5	0.0	0.3	0.0	0.5	1.1	-0.4	0.5	0.0
Average weekly red wine intake	0.4	0.6	4.3	-0.0	-0.1	2.1	1.4	-1.2	-0.6	0.5	0.2	0.1	-0.3	0.7	0.2	-0.5	0.7	0.6	0.4	-0.2	0.9	-0.9
Loneliness, isolation	0.4	0.6	1.7	0.9	0.5	-0.8	-0.1	0.2	1.3	-0.1	1.3	0.6	1.2	-0.2	-0.1	1.0	0.5	0.8	0.7	-1.1	-0.6	0.8
Hearing aid user	0.4	0.5	2.4	-1.4	-0.2	-1.5	0.3	-0.5	0.8	0.1	0.3	-0.6	0.5	0.6	0.5	-0.4	-0.4	0.5	-0.8	-1.3	-0.2	-0.2
Commuting to job workplace: Public transport	0.4	0.5	2.0	0.5	-0.1	0.9	0.1	-0.9	-1.0	-0.5	-0.1	-0.5	-1.4	0.2	0.3	-0.5	0.0	-0.4	-1.2	0.7	0.4	-0.7
Medication: Paracetamol	0.4	0.5	1.7	-0.4	-0.6	-1.2	-0.4	-0.8	0.5	-0.3	0.0	-1.1	1.0	-0.6	-0.4	-0.8	-0.1	0.1	-0.6	-1.2	-0.4	-1.3
Fractured/broken bones in last 5 years	0.4	0.6	1.7	-0.7	-0.8	-1.3	-1.1	-0.7	0.2	-0.8	-0.4	-0.8	0.2	-0.9	-0.5	-0.7	-0.9	-0.4	-0.8	-0.6	-0.8	-1.0
Ever depressed for a whole week	0.4	0.5	2.4	-0.1	-0.8	-0.4	-0.1	-1.2	0.0	0.1	-0.6	-1.2	0.2	-0.8	-0.4	-0.5	-0.7	-0.2	-0.9	0.2	-0.5	-1.6
Alzheimer’s Disease (including proxy)	0.3	0.5	1.6	0.4	0.9	-0.7	0.2	0.3	1.3	0.7	0.7	0.3	1.2	0.6	0.7	0.5	0.3	0.4	0.3	0.0	0.7	0.9
Breast Cancer	0.3	0.7	4.0	0.8	0.0	-1.4	-1.1	-0.6	-0.0	-1.0	0.6	-0.4	0.6	-0.8	-0.8	-0.3	0.6	0.2	-0.6	-2.0	-0.1	-1.3
LDL Cholesterol	0.3	0.5	1.8	-0.7	-0.6	-1.3	-0.2	-0.8	0.0	-0.9	-0.0	-0.6	0.2	-0.5	-0.6	-0.5	-0.8	-0.2	-0.6	-1.3	-1.2	-0.3
Type 2 Diabetes (T2D) (2012)	0.3	0.4	2.2	1.5	0.5	0.5	-0.3	0.1	-0.1	0.3	0.6	0.4	-0.6	-0.0	0.4	0.6	0.9	0.6	-0.3	0.7	0.6	0.6
Hair Pigment	0.3	9.1	19.6	2.4	3.2	1.9	2.5	3.2	3.7	3.1	2.8	3.4	3.5	2.1	2.7	4.4	2.5	3.3	3.3	2.4	2.3	3.2
Severe depression (siblings)	0.3	0.3	2.4	0.3	-0.4	1.5	-0.3	-0.6	-0.5	0.4	0.7	-0.4	-0.4	-0.7	0.3	-0.2	0.9	0.5	0.2	-0.2	0.2	-0.3
Townsend deprivation index at recruitment	0.3	0.4	1.2	-0.5	-0.7	0.9	-0.1	-0.3	-0.6	-0.4	-0.8	-0.9	-0.5	-0.7	-0.2	-0.4	-0.2	-0.3	-0.5	1.0	-0.3	-1.1
Stomach or abdominal pain in last month	0.3	0.4	2.0	0.3	0.2	0.6	-0.3	1.4	-0.1	0.1	0.7	0.7	0.1	-0.5	0.2	1.0	0.8	0.2	1.0	-0.3	-0.3	1.0
Supplements: Glucosamine	0.3	0.4	1.2	0.3	0.4	0.9	0.9	0.5	-0.4	1.0	-0.0	0.5	-0.6	0.7	0.7	0.2	0.6	0.7	-0.2	0.8	1.1	0.2
High blood pressure (mother)	0.3	0.4	2.3	-0.3	-0.7	-0.4	-0.8	-0.1	-0.7	-1.5	0.2	-0.2	-0.1	-0.2	-0.4	-0.7	0.5	-0.0	-0.1	-1.4	-0.6	-0.6
Impedance of leg (left)	0.3	1.5	6.4	1.2	-0.5	0.1	-0.7	-1.3	-2.2	-0.7	-0.8	-0.9	-2.0	-0.7	-0.4	-1.1	0.2	-0.3	-2.5	-0.4	0.6	-2.2
Forced vital capacity (FVC)	0.3	1.3	2.5	1.3	1.4	1.4	1.6	1.0	0.0	0.9	0.6	1.5	-0.0	1.4	1.3	1.0	1.1	1.1	0.4	1.1	1.6	0.8
Falls in the last year	0.3	0.4	1.3	-0.3	0.3	0.4	0.4	0.4	1.0	1.1	1.1	-0.0	0.7	0.7	0.7	0.4	1.0	0.6	0.7	0.1	0.5	0.8
Pulse wave Arterial Stiffness index	0.3	0.4	1.9	0.4	0.7	-1.0	0.3	-0.1	0.3	-0.5	0.6	0.4	0.9	0.8	0.1	0.0	0.4	0.7	-0.2	-1.4	0.7	-0.5
Loud music exposure frequency	0.3	0.3	3.6	-0.9	-0.3	1.9	0.5	0.2	-0.3	0.1	0.1	-0.0	-0.4	0.1	0.1	0.2	0.5	0.3	0.9	0.6	0.1	-0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.1	-0.4	-0.2	-1.2	-0.5	-0.4	-0.4	-0.4	-0.2	-0.5	0.2	0.0	0.1	-0.9	0.0	0.4	-1.5	-0.7	0.4	-1.1
Leg fat percentage (right)	0.3	1.1	4.8	-0.3	0.6	-0.4	0.2	2.2	1.2	0.3	-0.1	1.2	1.2	0.3	0.1	1.6	-0.4	0.0	1.1	1.9	-0.3	1.6
Wheeze or whistling in the chest in last year	0.3	0.5	1.6	-0.3	0.6	-0.4	0.0	1.3	0.7	0.2	0.9	0.8	1.0	0.3	0.5	0.7	0.8	0.7	0.5	-0.2	0.1	1.1
Heart disease (mother)	0.3	0.4	1.2	-1.1	-0.7	-0.4	-0.6	-0.2	-0.6	-0.7	-0.2	-0.7	-0.6	-0.8	-0.4	-0.4	-0.3	-0.6	-0.1	-1.0	-1.1	0.1
Chest pain or discomfort	0.3	0.4	2.3	-0.2	0.5	-0.4	-0.3	1.5	0.4	-0.3	0.1	0.6	1.1	0.0	-0.1	0.7	0.1	-0.3	1.1	-0.3	-0.2	1.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.8	-0.8	-0.4	-0.3	0.6	-1.3	-0.0	0.5	-0.1	-0.8	-0.2	0.2	0.4	-0.5	-0.3	0.4	-0.6	-0.9	-0.1	-0.6
Qualifications: nursing, teaching	0.3	0.4	1.8	-0.5	-0.7	1.4	0.2	-0.2	-1.2	-0.3	-0.4	-0.4	-1.3	-0.2	0.2	-0.3	-0.1	-0.1	-0.6	0.9	-0.1	-0.6
Miserableness	0.3	0.5	1.5	-0.0	0.2	-0.8	0.2	0.6	0.8	-0.3	0.9	0.5	0.9	0.2	0.2	0.5	0.4	0.4	0.8	-1.2	-0.9	1.2
Unable to work because of sickness or disability	0.3	0.4	2.0	-1.4	-0.0	0.7	0.5	0.7	0.5	1.1	0.2	0.3	0.1	0.4	0.3	0.4	-0.1	0.0	0.7	0.4	-0.0	1.4
Myopia	0.3	0.5	1.4	0.4	0.4	-0.5	0.9	-1.1	0.8	0.2	1.2	-0.0	0.9	1.2	0.8	-0.4	0.7	0.5	0.2	-1.0	0.3	0.1
Basal cell carcinoma (self-reported)	0.3	0.4	1.7	-0.3	-0.4	-0.9	0.6	-1.3	0.8	0.2	0.3	-0.7	0.6	0.3	0.1	-0.7	-0.4	0.2	0.2	-1.1	-0.6	-0.7
Schizophrenia vs Biploar Disorder	0.2	0.3	2.3	-1.1	-0.3	-0.2	-0.2	0.7	0.1	-0.2	0.3	0.1	0.1	-0.0	0.1	0.3	-0.0	-0.3	0.5	-0.5	-1.0	1.5
Crohns Disease (2012)	0.2	0.4	2.0	-0.3	0.4	-0.4	-0.0	0.8	0.4	0.3	-0.7	0.4	1.4	-0.1	-0.8	0.3	-0.9	-0.6	0.9	0.4	0.2	0.5
Primary Biliary Cirrhosis	0.2	0.3	2.0	-0.1	-0.1	0.1	0.2	0.4	-0.3	-0.0	-1.4	-0.3	0.1	0.1	-0.4	0.1	-1.1	-0.7	-0.2	1.3	0.2	-0.4
Ever had hysterectomy (womb removed)	0.2	0.2	1.2	0.3	0.5	-0.9	-0.0	0.8	0.7	0.1	-0.2	-0.0	1.1	0.3	0.2	0.3	-0.1	-0.2	0.4	0.4	0.3	0.5
Medication: Metformin	0.2	0.3	2.0	0.3	0.0	0.9	-0.6	0.9	-0.3	0.3	-0.0	0.2	-0.5	-0.4	-0.3	0.4	0.4	-0.4	0.7	1.4	0.2	0.7
Diabetes (mother)	0.2	0.3	3.0	-0.5	-0.2	0.2	0.4	-0.5	-0.2	-0.2	0.7	-0.1	0.1	0.5	0.2	-0.2	0.6	0.3	0.7	-1.7	-0.2	-0.1
Pack years adult smoking proportion	0.2	0.3	1.0	-0.4	-0.6	-0.6	-0.4	-0.8	0.1	-0.8	0.4	-0.7	-0.3	-0.3	-0.2	-0.5	0.0	-0.2	-0.1	-1.0	-1.0	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	-0.8	0.1	-0.4	0.9	0.2	0.7	0.5	-0.2	-0.2	0.9	0.8	0.2	0.0	-0.4	-0.2	0.8	0.1	-0.1	0.3
Qualifications: CSEs or equivalent	0.2	0.3	1.0	0.4	-0.2	-0.2	-0.1	-0.3	-0.6	-0.8	-0.3	0.1	-1.0	-0.4	-0.8	-0.1	-0.5	-0.8	-0.3	-0.1	-0.6	-0.3
Hearing difficulty/problems with background noise	0.2	0.3	1.5	0.5	0.3	-0.9	-0.6	0.7	0.8	0.3	-0.2	0.2	1.2	-0.7	-0.3	0.5	-0.4	-0.2	0.5	0.6	-0.1	0.0
Mouth/teeth dental problems	0.2	0.3	1.2	-0.7	-0.2	-0.9	-0.5	0.2	0.5	-0.6	0.3	0.2	1.1	0.0	-0.3	-0.6	0.0	0.3	0.1	-1.0	-0.2	-0.3
Impedance of arm (right)	0.2	0.8	4.3	0.7	-0.4	0.3	0.2	-1.4	-1.2	-0.1	-0.4	-1.1	-1.2	0.2	0.2	-1.0	0.2	-0.1	-2.1	0.3	0.6	-1.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.7	0.8	0.2	0.8	0.6	-0.3	-0.4	0.0	0.1	0.1	-0.1	0.4	0.3	-0.2	0.7	0.4	0.2	-0.4	0.4	-0.9
Illnesses of mother	0.2	0.2	0.8	0.7	0.4	-0.2	-0.3	0.2	0.4	0.4	-0.5	0.2	-0.2	-0.3	-0.3	0.3	-0.6	-0.6	0.2	0.9	0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.6	0.4	0.8	1.1	1.3	0.7	-0.1	0.9	0.2	1.0	-0.2	1.1	1.1	0.9	0.4	0.5	0.2	1.2	1.0	1.1
Exposure to tobacco smoke at home	0.2	0.2	2.2	1.5	0.3	0.6	-0.3	-0.2	-0.3	0.0	0.2	0.2	-0.5	-0.1	-0.0	0.2	0.4	-0.2	-0.3	0.6	0.4	-0.0
Pulse wave reflection index	0.2	0.2	1.2	0.3	0.1	-1.1	-0.5	-0.2	0.4	-0.3	0.3	0.1	0.8	-0.3	-0.4	-0.0	0.0	0.1	0.1	-1.1	-0.2	-0.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.1	0.2	-0.2	0.0	0.4	-1.0	-0.2	0.3	-0.7	-0.5	-0.0	-0.2	-0.4	-0.2	-0.9	-0.3	-0.4	0.3	-0.1	-0.7
Forced vital capacity (FVC), Best measure	0.2	0.6	1.9	0.4	0.8	1.0	1.4	0.4	-0.2	0.8	0.3	1.1	-0.4	1.0	1.0	0.7	0.5	0.9	-0.2	0.7	0.9	0.6
Number of children fathered	0.2	0.2	1.0	-0.9	-0.2	0.5	-0.3	1.0	-0.1	0.5	-0.8	0.2	0.1	-0.6	-0.1	0.2	-0.2	-0.1	0.5	1.0	0.2	-0.0
Health satisfaction	0.2	0.3	1.2	0.1	0.2	0.9	0.1	0.7	-0.3	0.2	0.5	0.4	0.1	0.3	0.1	0.3	0.8	-0.4	1.1	0.1	0.1	0.9
Medication: Ibuprofen	0.2	0.2	0.7	0.8	0.2	0.9	0.6	-0.1	-0.5	0.0	0.1	0.3	-0.2	0.6	0.3	-0.2	0.8	0.3	0.4	-0.2	0.6	-0.8
Medication: Allopurinol	0.2	0.2	1.6	-0.5	0.0	0.9	0.1	0.6	-0.1	0.3	0.2	0.5	0.2	0.1	-0.3	0.3	0.4	-0.1	1.3	-0.2	0.1	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.0	-0.8	-0.4	0.2	0.2	-1.0	-0.1	-0.5	0.3	-0.6	-0.4	0.3	0.4	-0.9	0.2	-0.0	0.3	-1.0	-0.1	-0.4
Mother’s age at death	0.2	0.3	1.6	0.1	0.3	-0.1	0.1	0.9	0.3	0.1	-0.7	0.8	0.5	-0.0	0.1	0.7	-0.6	0.0	0.2	1.3	0.1	0.0
Average weekly beer plus cider intake	0.2	0.3	1.5	-0.7	-0.5	0.0	-0.2	-0.2	-0.5	-0.8	0.2	0.0	-0.6	-0.5	-0.5	0.1	-0.2	-0.3	0.2	-1.2	-1.2	0.5
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.9	-0.8	-0.6	-0.1	0.2	-1.0	-0.2	0.4	-0.6	-0.6	-0.2	0.0	-0.3	-0.9	-0.6	-0.2	-0.5	-0.2	-0.1	-0.7
Impedance of whole body	0.2	1.1	4.6	1.2	-0.4	0.6	-0.1	-1.2	-1.8	-0.2	-0.5	-0.8	-1.6	-0.2	0.1	-0.9	0.5	-0.0	-2.1	0.2	0.8	-1.9
Lupus	0.1	0.1	0.7	0.3	-0.3	0.0	-0.1	-0.4	-0.7	-0.7	-0.1	-0.4	-0.3	0.2	-0.1	-0.3	0.1	-0.1	-0.6	-0.1	0.1	-0.8
Waist Hip Ratio (WHR)	0.1	0.5	2.3	1.5	0.0	0.0	-0.7	-0.7	-0.5	-0.7	1.0	0.0	0.0	-0.4	-0.3	-0.4	1.2	0.0	-0.7	-1.1	-0.1	-0.3
Lung FEV1/FVC ratio	0.1	0.5	5.2	0.3	0.3	-0.0	0.3	0.6	0.5	0.9	-0.8	-0.0	0.7	0.6	0.3	0.3	-0.8	-0.7	-0.2	2.3	0.6	0.6
Chronotype (morning person)	0.1	0.2	1.2	1.1	-0.0	-0.1	-0.5	-0.3	-0.1	-0.5	-0.2	-0.2	-0.2	-0.4	-0.5	-0.3	-0.1	-0.5	0.3	-0.1	-0.1	-0.8
Tanning	0.1	1.4	3.4	-1.4	-1.4	-0.2	-0.6	-1.4	-1.2	-1.6	-0.5	-1.4	-0.8	-0.8	-1.1	-1.5	-0.5	-1.4	-0.0	-1.8	-1.6	-1.0
Average weekly spirits intake	0.1	0.1	0.5	-0.7	-0.0	-0.7	0.3	-0.1	0.2	0.0	-0.1	0.3	0.2	0.3	0.1	-0.0	-0.5	0.1	0.1	-0.7	-0.5	0.2
Chronic bronchitis/emphysema (father)	0.1	0.2	1.1	1.0	0.4	0.5	-0.4	0.3	-0.3	-0.3	0.4	0.2	-0.3	-0.2	0.0	0.4	0.6	0.1	-0.1	0.4	0.3	0.1
Had menopause	0.1	0.2	1.0	-0.2	0.3	0.1	0.1	1.0	-0.3	-0.1	0.3	0.5	-0.1	0.3	0.2	0.4	0.5	-0.1	0.6	-0.7	0.1	0.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.4	-0.3	-0.4	-0.1	0.3	-0.7	0.3	0.3	-0.3	-0.4	0.5	-0.5	-0.1	0.0	-0.5	0.2	-0.1	0.2	-0.5	-0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	1.0	-0.4	-0.6	-0.3	-0.5	-0.5	-0.0	-0.2	-0.1	-0.8	-0.5	-0.8	-0.2	0.1	-0.3	-0.4	-0.1	-0.4	-1.0	-0.0
Lung cancer (father)	0.1	0.2	0.9	-1.0	-0.4	-0.1	-0.1	1.0	-0.2	-0.2	-0.1	0.4	-0.2	-0.3	-0.1	0.3	-0.2	0.6	-0.4	0.1	-0.2	-0.3
Impedance of arm (left)	0.1	0.4	2.0	0.7	0.0	0.6	0.6	-0.4	-0.6	0.6	0.0	-0.4	-0.4	0.4	0.7	-0.2	0.6	0.5	-1.4	0.7	0.9	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	0.6	0.5	-0.5	0.5	-0.2	0.6	0.5	0.5	0.2	0.2	0.4	0.3	0.5	0.1	0.7	-0.7	0.2	0.1	0.3
Blood clot in the leg (DVT)	0.1	0.1	0.6	0.8	0.3	-0.1	0.0	-0.0	0.4	0.1	-0.3	0.1	0.3	-0.2	-0.4	0.3	-0.3	-0.3	0.7	0.3	-0.1	-0.2
Gout (self-reported)	0.1	0.1	0.6	-0.5	-0.2	0.6	-0.3	0.2	-0.8	-0.3	-0.5	-0.0	-0.4	0.0	-0.3	-0.3	0.2	-0.4	0.1	0.2	0.3	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.8	0.8	0.3	0.0	0.1	0.4	0.1	-0.2	0.9	0.5	-0.1	0.2	0.3	0.5	0.5	0.3	-0.3	0.2	-0.1	0.6
Guilty feelings	0.1	0.2	0.8	0.3	-0.1	-0.5	-0.9	0.6	-0.3	-0.8	-0.2	-0.1	0.4	-0.7	-0.6	-0.0	-0.2	-0.5	0.1	-0.3	-0.5	-0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.6	-0.4	0.2	-0.3	0.8	0.0	0.2	0.4	-0.2	0.3	0.1	0.3	0.4	0.6	-0.3	0.4	-0.2	0.1	-0.1	0.7
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	1.0	1.0	0.2	-0.1	-0.1	-0.1	0.2	-0.1	-0.3	0.1	0.1	-0.2	-0.5	0.2	-0.2	-0.3	0.6	0.3	-0.1	-0.3
Pack years of smoking	0.1	0.1	0.5	-0.1	-0.4	-0.5	-0.3	-0.5	0.2	-0.6	0.3	-0.5	-0.1	-0.2	-0.1	-0.2	0.1	0.0	-0.1	-0.5	-0.7	-0.5
Relative age of first facial hair	0.0	0.1	0.5	-0.1	-0.1	-0.7	-0.0	-0.2	0.3	-0.5	-0.0	-0.3	0.3	0.1	-0.0	-0.3	-0.3	-0.1	-0.5	0.0	-0.4	0.1
Age when periods started (menarche)	0.0	0.1	0.3	-0.1	0.1	-0.5	-0.2	0.2	-0.1	-0.5	0.4	0.1	-0.1	0.3	0.0	-0.0	0.1	-0.0	-0.5	-0.5	-0.1	0.5

Hub : Genes

FLJ13197

Models

Trait associations