Hub : Genes

MTFR1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0710 0.0250 7.9e-05 0.044 0.028 0.033 0.029 0.038 4.1e-06 2.0e-04 6.7e-05 1.6e-04 1.6e-05
2 GTEx Adipose Visceral Omentum 0.2390 0.0920 1.9e-03 0.095 NA 0.016 NA 0.057 1.3e-05 NA 5.0e-02 NA 6.7e-04
3 GTEx Artery Tibial 0.2509 0.0651 1.2e-06 0.157 NA 0.124 NA 0.140 2.5e-12 NA 5.8e-10 NA 4.3e-11
4 GTEx Colon Transverse 0.1280 0.0520 3.4e-03 0.011 NA 0.028 NA 0.038 9.0e-02 NA 1.6e-02 NA 6.5e-03
5 GTEx Esophagus Mucosa 0.1530 0.0500 7.0e-05 0.087 NA 0.071 NA 0.046 2.1e-06 NA 1.8e-05 NA 4.7e-04
6 GTEx Muscle Skeletal 0.1359 0.0340 3.7e-10 0.178 NA 0.120 NA 0.151 3.7e-17 NA 7.5e-12 NA 1.3e-14
7 GTEx Nerve Tibial 0.2037 0.0632 1.4e-04 0.005 NA 0.041 NA 0.039 1.4e-01 NA 6.3e-04 NA 8.9e-04
8 GTEx Skin Sun Exposed Lower leg 0.1090 0.0350 3.2e-04 0.059 NA 0.102 NA 0.118 1.3e-05 NA 8.2e-09 NA 5.1e-10
9 GTEx Testis 0.1950 0.0800 8.1e-03 0.036 NA 0.116 NA 0.116 1.0e-02 NA 7.9e-06 NA 7.9e-06
10 METSIM Adipose 0.1511 0.0425 3.3e-11 0.126 0.076 0.111 0.122 0.123 2.6e-18 2.0e-11 3.0e-16 9.7e-18 5.7e-18
11 NTR Blood 0.0260 0.0098 4.8e-04 0.025 0.010 0.019 0.020 0.019 1.1e-08 2.2e-04 7.6e-07 4.2e-07 5.6e-07
12 YFS Blood 0.1245 0.0266 0.0e+00 0.099 0.096 0.099 0.104 0.098 9.4e-31 8.5e-30 1.6e-30 4.1e-32 2.1e-30
13 TCGA Bladder Urothelial Carcinoma 0.0830 0.0490 5.0e-03 0.019 0.034 0.032 NA 0.027 9.6e-03 6.9e-04 8.8e-04 NA 2.0e-03
14 TCGA Breast Invasive Carcinoma 0.0319 0.0196 2.4e-03 0.008 0.006 0.009 NA 0.006 7.4e-03 1.5e-02 3.9e-03 NA 1.4e-02
15 TCGA Cervical Squamous Cell Carcinoma 0.0470 0.0290 7.9e-03 0.011 0.033 0.027 NA 0.013 8.8e-02 9.5e-03 1.7e-02 NA 7.3e-02
16 TCGA Kidney Renal Clear Cell Carcinoma 0.0974 0.0394 3.9e-06 0.060 0.057 0.054 NA 0.058 2.5e-07 5.3e-07 1.1e-06 NA 3.9e-07
17 TCGA Kidney Renal Papillary Cell Carcinoma 0.0530 0.0280 1.5e-03 0.023 0.021 0.001 NA 0.015 1.6e-02 2.2e-02 2.9e-01 NA 4.3e-02
18 TCGA Brain Lower Grade Glioma 0.0417 0.0319 8.7e-03 0.003 0.006 0.006 NA 0.006 1.5e-01 6.0e-02 5.7e-02 NA 6.2e-02
19 TCGA Ovarian Serous Cystadenocarcinoma 0.0560 0.0300 3.7e-04 0.033 0.047 0.030 NA 0.040 2.5e-03 3.8e-04 3.7e-03 NA 9.8e-04
20 TCGA Testicular Germ Cell Tumors 0.2010 0.1380 6.5e-03 0.029 0.041 0.010 NA 0.039 3.2e-02 1.4e-02 1.4e-01 NA 1.6e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bipolar Disorder (2018) 0.9 1.4 3.3 1.4 -1.3 -1.8 -1.8 -0.3 -1.3 -0.4 0.7 0.6 -1.2 -0.9 -1.6 1.8 -0.1 -0.9 -1.2 -1.2 -0.1 -1.0 -1.6
Bipolar Disorder or Schizophrenia 0.7 1.8 3.4 1.4 -1.7 -1.9 -1.4 -0.5 -1.6 -1.0 -0.0 0.4 -1.6 -1.1 -1.5 1.1 -0.4 -1.7 -1.0 -1.7 -1.2 -1.8 -1.6
Depressed Affect (Nagel 2018) 1.0 2.1 6.8 -0.8 0.9 1.1 1.3 2.0 1.1 1.0 1.0 -0.5 1.0 0.7 1.2 -0.1 2.2 2.5 1.0 2.2 0.8 2.6 1.6
Depression (Nagel 2018) 0.7 1.1 5.0 -0.2 0.6 1.0 1.6 1.1 0.9 0.3 0.5 -1.2 1.0 1.0 1.3 0.1 2.2 0.9 1.2 0.9 -1.2 1.1 0.6
Intelligence (Savage-Jansen 2018) 2.9 8.9 24.4 2.6 -2.4 -2.5 -1.6 -4.9 -2.8 -1.5 -0.7 1.6 -2.8 -1.8 -2.7 1.0 -3.2 -4.7 -3.2 -4.6 -1.9 -4.6 -3.3
Neuroticism (Nagel 2018) 1.0 2.4 6.0 -1.6 0.9 1.1 1.9 2.2 1.3 0.1 0.6 -0.8 1.2 1.1 1.5 -0.7 2.2 2.3 1.6 2.2 0.5 2.4 1.9
Schizophrenia (2018) 0.4 0.8 2.2 0.7 -1.1 -1.0 -0.4 -0.4 -0.9 -1.0 -0.6 0.1 -1.0 -0.7 -0.7 0.1 -0.5 -1.4 -0.3 -1.3 -1.5 -1.4 -0.8
Schizophrenia vs Biploar Disorder 0.6 0.9 2.7 -1.5 0.4 0.8 1.5 0.5 0.6 0.6 -0.5 -0.1 0.6 0.3 0.8 -1.6 0.5 1.1 0.9 1.2 -0.2 1.2 1.3
Worry (Nagel 2018) 1.5 3.2 6.0 -1.3 1.5 1.3 2.5 2.4 1.9 0.1 0.7 -1.5 1.9 2.0 2.1 -0.4 1.8 2.0 2.1 2.1 1.5 2.1 2.0
Alzheimer’s Disease (in mother) 0.6 0.7 1.6 1.2 -0.6 -1.2 0.2 -1.2 -0.8 0.6 -0.3 0.9 -0.8 -0.6 -0.7 -0.1 -1.1 -1.0 -1.3 -0.9 0.1 -1.1 -0.5
Alzheimer’s Disease (in father) 0.3 0.3 1.6 -1.1 -0.0 0.1 0.7 0.2 0.4 -1.3 -1.0 -0.3 0.4 0.4 0.1 -1.0 -0.3 0.1 0.9 0.2 -0.4 -0.0 0.2
Alzheimer’s Disease (including proxy) 0.1 0.2 0.9 0.2 -0.0 -0.6 1.0 -0.4 0.0 -0.0 -0.5 -0.0 0.1 0.2 -0.1 -0.6 -0.2 -0.5 0.0 -0.4 -0.5 -0.5 0.1
Crohns Disease (2017) 0.6 1.3 5.0 2.2 1.1 0.5 0.3 0.1 0.8 0.9 1.3 -1.7 0.7 1.2 0.7 1.3 0.6 -1.7 0.1 -1.5 -0.4 -1.8 -0.4
Irritable Bowel Disease (IBD) 1.5 3.6 8.6 2.0 2.7 1.9 1.9 1.4 2.4 2.2 2.0 -2.9 2.4 2.9 2.5 0.6 1.8 -0.3 1.6 -0.1 0.6 -0.3 1.3
Ulcerative Colitis (UC) 1.5 2.9 6.3 0.7 2.3 1.6 1.7 1.7 2.2 1.8 1.2 -2.3 2.3 2.5 2.3 -0.6 1.6 0.7 2.0 0.8 0.5 0.6 1.9
Major Depression (MDD) 3.5 4.3 9.3 1.5 -1.7 -2.7 -2.1 -1.7 -2.2 -0.9 -1.0 1.5 -2.2 -1.6 -1.8 0.6 -2.5 -3.0 -2.4 -3.0 -1.1 -3.0 -2.3
Reaction Time 0.5 1.0 2.7 1.6 -0.5 -0.4 -0.8 -1.4 -0.8 -0.4 0.4 0.0 -0.8 -0.6 -0.9 1.0 -0.9 -1.6 -1.0 -1.6 -0.5 -1.5 -1.3
Verbal and Numeric Reasoning (VNR) 2.0 4.8 18.0 1.9 -1.7 -1.5 -1.0 -4.2 -1.9 -1.7 -0.1 0.5 -1.9 -1.0 -2.0 1.9 -1.9 -3.2 -1.9 -3.1 -1.8 -3.2 -2.8
Breast Cancer 0.2 0.6 2.4 -1.0 0.6 -0.5 -0.1 1.5 0.7 0.4 -0.7 -0.1 0.8 0.8 0.3 -0.5 -0.2 0.8 0.8 1.1 1.1 0.7 0.8
Ovarian Cancer 0.4 0.5 2.7 0.4 -0.3 -0.1 0.3 -0.7 0.1 0.2 1.2 -0.9 0.1 0.3 0.4 1.6 1.5 0.1 0.8 0.2 -0.2 0.1 -0.5
Prostate Cancer 1.1 1.5 4.9 1.4 -1.0 -0.7 -0.4 -0.6 -1.1 -0.9 -0.7 0.4 -1.0 -0.7 -1.0 0.3 -1.0 -2.1 -1.3 -2.1 -1.5 -2.2 -1.4
Age at First Birth 0.6 0.9 3.2 -1.8 -0.5 -0.2 -0.4 -1.5 -0.5 -1.7 -1.5 1.0 -0.6 -0.9 -0.9 -1.0 -1.0 -0.3 -0.5 -0.5 -1.3 -0.5 -0.3
Bipolar Disorder (2011) 1.2 1.2 5.7 1.8 -1.0 -1.0 -0.8 0.6 -0.9 -0.8 1.2 0.4 -0.9 -0.7 -1.2 2.4 -0.2 -0.6 -1.1 -0.9 0.4 -0.7 -1.6
Body Mass Index (BMI) (2010) 0.2 0.3 1.6 -0.5 0.5 0.3 0.2 0.7 0.3 0.5 0.2 0.2 0.3 -0.0 -0.1 -0.1 0.4 1.3 0.2 1.1 0.7 1.1 0.4
Coronary Artery Disease (CAD) 0.3 0.4 1.0 0.8 -0.3 -0.2 0.7 0.7 0.1 -0.1 0.6 -0.9 0.0 0.4 0.1 1.0 0.4 -0.6 0.3 -0.6 -0.9 -0.6 -0.8
Crohns Disease (2012) 1.2 2.0 5.3 1.4 1.6 1.7 0.7 2.2 1.8 -0.2 1.4 -2.3 1.7 2.0 1.9 1.1 1.4 0.0 1.4 0.2 0.2 -0.0 0.3
Mean Putamen Volume 0.7 0.8 4.8 -1.7 -0.6 0.1 -0.2 -0.0 -0.2 -1.4 -2.2 1.1 -0.2 -0.5 -0.2 -1.9 -0.4 0.1 -0.1 0.5 0.1 -0.1 0.4
Fasting Glucose 0.6 0.7 1.9 -0.9 0.5 0.9 0.4 1.0 0.7 0.4 -0.0 0.0 0.8 0.5 0.4 -0.8 0.5 1.4 0.8 1.3 0.9 1.4 1.2
HbA1C 0.5 0.5 4.5 -0.9 0.1 -0.3 -0.5 -0.0 -0.0 0.1 -1.1 1.0 0.1 -0.2 0.2 -2.1 -1.0 0.4 -0.4 0.2 0.3 0.4 0.8
HDL Cholesterol 0.3 0.5 3.7 0.0 -0.8 0.2 -0.3 -0.4 -0.5 -1.2 1.2 -0.0 -0.4 -0.4 -0.1 1.9 0.7 0.5 0.1 0.4 0.3 0.5 -0.6
LDL Cholesterol 0.4 0.7 2.6 -0.3 -0.0 -0.6 -0.2 -0.5 -0.5 0.1 -1.6 1.2 -0.6 -0.7 -0.9 -1.6 -1.5 -0.6 -1.0 -0.7 -0.2 -0.7 0.1
Lupus 0.9 1.4 4.2 -0.5 1.3 0.9 1.1 1.7 1.0 1.2 1.7 -0.6 1.0 0.7 0.4 0.8 0.8 1.7 0.7 1.4 2.0 1.7 1.0
Neuroticism (2016) 0.6 0.9 2.1 0.9 -0.4 -1.1 -0.8 -0.4 -1.1 1.2 -0.0 1.4 -1.1 -0.9 -0.6 -0.1 -1.3 -1.0 -1.4 -1.0 1.1 -0.8 -0.2
Primary Biliary Cirrhosis 0.3 0.4 1.5 -0.6 -0.0 0.2 -0.3 0.3 0.2 0.7 -0.0 0.1 0.4 -0.0 0.5 -0.9 0.8 1.2 0.5 1.0 -0.3 1.2 0.8
Rheumatoid Arthritis 1.6 2.2 6.5 2.4 -0.8 -1.3 -1.7 -2.1 -1.3 0.3 1.0 0.8 -1.3 -1.1 -1.2 2.6 -1.2 -1.3 -1.9 -1.6 0.1 -1.2 -2.1
Schizophrenia (2014) 1.0 2.1 3.9 0.5 -2.0 -1.8 -1.5 -0.6 -1.8 -1.6 -1.4 1.2 -1.8 -1.7 -1.6 -0.2 -0.9 -1.6 -1.2 -1.5 -1.6 -1.7 -1.4
Triglycerides 0.7 1.1 3.5 -0.4 1.5 0.8 0.7 0.9 1.1 1.9 -0.1 -0.4 1.1 0.9 1.1 -1.4 0.3 1.0 0.5 1.0 1.2 1.1 1.7
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.8 -1.0 -0.6 -0.4 -0.8 -0.1 -0.4 -1.7 -1.5 0.7 -0.4 -0.6 -0.2 -0.8 -0.6 -0.5 -0.9 -0.5 -1.1 -0.6 -1.0
Ulcerative Colitis 2.0 2.9 5.5 -0.0 2.0 2.1 2.3 1.8 2.2 0.8 0.8 -1.9 2.3 2.3 2.3 -0.8 1.3 1.1 2.1 1.2 1.2 1.2 1.9
Blood Eosinophil Count 0.8 6.3 13.0 3.5 -2.7 -3.6 -2.3 -1.4 -2.6 -1.0 0.9 0.6 -2.6 -1.7 -1.6 2.3 -0.9 -3.2 -2.1 -3.5 -3.2 -3.0 -3.6
Blood Platelet Count 1.8 21.2 40.7 6.0 -3.7 -4.1 -5.1 -5.1 -4.9 -0.8 1.0 2.0 -4.9 -3.7 -3.8 4.9 -3.5 -5.9 -5.3 -6.4 -3.0 -5.7 -6.4
Blood Red Count 0.4 4.3 25.6 5.1 -0.7 -1.3 -1.9 -1.6 -1.5 2.4 3.0 -0.1 -1.4 -0.5 -0.4 3.9 -0.3 -1.9 -1.8 -2.0 0.8 -1.5 -1.7
Blood White Count 0.1 0.7 3.2 0.1 -0.3 -0.8 -1.8 -0.5 -0.8 1.2 -0.2 1.0 -0.8 -1.0 -0.3 -0.9 -0.9 -0.5 -1.1 -0.9 -1.1 -0.5 -0.2
Heel T-Score 0.2 1.3 2.4 0.7 -1.4 -0.4 -1.6 -1.1 -1.3 -0.6 -0.2 0.8 -1.3 -1.4 -1.3 1.1 -0.8 -1.3 -1.2 -1.2 -0.3 -1.4 -1.5
BMI 1.0 5.7 12.0 -1.3 -2.5 -3.1 -2.6 -1.9 -2.5 -1.1 -3.4 3.3 -2.5 -3.0 -2.4 -3.4 -1.9 -0.6 -2.2 -1.0 -3.5 -0.9 -1.0
Height 0.1 2.2 8.5 1.1 0.8 2.7 2.9 0.5 0.8 0.2 2.5 -1.4 0.9 1.2 1.0 1.9 1.0 0.4 1.0 0.4 2.4 0.7 0.8
Waist Hip Ratio (WHR) 1.2 5.4 10.5 3.2 -2.6 -2.3 -1.7 -2.5 -2.9 -1.0 0.6 1.4 -2.8 -2.2 -2.0 2.3 -1.3 -2.7 -2.7 -2.8 -1.5 -2.8 -2.9
Systolic Blood Pressure 0.2 1.0 3.7 -1.1 -1.2 -1.3 -1.9 -0.2 -0.9 -0.4 -1.4 1.2 -0.9 -1.2 -0.7 -1.4 -0.3 0.0 -0.6 -0.2 -1.6 -0.1 -0.2
Smoking Status 4.7 11.3 23.2 3.4 -3.1 -3.8 -2.7 -3.5 -3.5 -1.7 -0.9 2.0 -3.6 -2.8 -3.6 1.5 -3.5 -4.8 -3.7 -4.8 -1.9 -4.8 -4.1
Allergy or Eczema 1.2 3.2 8.1 0.2 1.9 1.5 2.6 2.8 2.1 -0.1 1.3 -2.0 2.1 2.3 1.9 0.4 1.9 1.2 2.2 1.5 1.5 1.3 1.7
Cardiovascular Disease 0.9 3.1 6.4 -0.1 -2.0 -2.4 -1.4 -1.9 -1.8 -1.5 -1.8 1.4 -1.8 -1.7 -2.2 -0.5 -1.1 -1.7 -1.5 -1.9 -2.5 -1.8 -2.2
Hypothyroidism (self reported) 0.8 1.7 8.5 2.9 0.2 -0.4 0.4 -0.3 0.0 1.6 2.2 -1.5 0.0 0.8 0.4 2.9 1.7 -0.9 0.0 -1.0 -1.0 -0.6 -1.1
Respiratory disease 0.4 0.9 2.4 1.5 0.7 0.5 0.2 1.5 0.8 0.6 1.5 -1.0 0.8 1.0 0.9 1.5 1.1 0.5 0.7 0.5 1.1 0.6 0.4
Type 2 Diabetes (T2D) (2018) 0.5 0.9 2.0 0.1 -1.3 -1.2 -0.9 -1.4 -1.1 -0.7 -0.6 0.4 -1.0 -0.8 -0.9 -0.5 -0.5 -1.4 -0.6 -1.4 -1.3 -1.3 -0.6
Lung FEV1/FVC ratio 0.1 0.3 1.1 0.8 -0.4 0.7 -0.0 -0.3 -0.4 0.3 1.1 -0.2 -0.5 -0.6 -0.3 1.1 1.1 -0.2 -0.2 -0.5 -0.5 -0.1 -0.3
Lung FVC 0.2 1.2 3.0 -1.7 1.2 0.4 1.5 0.8 1.0 0.7 0.1 -0.1 1.0 0.7 1.1 -1.3 0.1 1.5 0.7 1.3 1.2 1.5 1.4
Neuroticism 0.7 1.6 5.3 -1.3 0.5 0.8 0.9 1.7 0.8 0.2 0.6 -0.4 0.8 0.6 1.3 -0.1 2.0 2.3 1.2 2.1 0.3 2.3 1.5
Chronotype (morning person) 0.5 1.1 2.7 -0.4 1.2 0.5 1.4 1.0 1.1 1.1 0.8 -0.4 1.1 0.9 0.8 0.1 0.1 1.6 0.7 1.5 1.0 1.6 0.9
Hair Pigment 0.0 0.6 1.6 -0.7 -1.2 -0.2 -1.1 0.5 -1.0 -0.5 -0.8 1.0 -1.0 -1.3 -0.3 -0.3 0.1 0.3 -0.6 0.1 -1.1 0.3 -0.4
Tanning 0.1 1.4 4.2 -0.4 1.1 0.9 0.6 2.0 1.5 0.1 0.7 -1.0 1.5 1.4 1.0 0.1 1.7 1.5 1.7 1.4 -0.2 1.4 0.9
Hand grip strength (left) 0.3 0.9 3.7 -1.9 0.2 0.3 0.8 0.9 0.8 -1.8 -0.7 -0.1 0.8 0.4 0.1 -1.2 0.1 0.9 1.1 1.3 0.7 0.6 1.0
Number of treatments/medications taken 0.5 1.0 3.5 1.6 -0.5 -0.9 0.5 0.1 -0.8 0.8 -0.3 0.3 -0.8 -0.5 -0.6 -0.4 -0.6 -1.8 -1.1 -1.9 -1.4 -1.4 -0.6
Average weekly spirits intake 0.4 0.6 2.2 0.5 -0.7 -0.1 1.1 -0.4 -0.4 -1.5 0.0 -0.4 -0.4 -0.1 -0.2 1.0 0.0 -1.0 -0.0 -0.9 -1.1 -0.9 -1.2
Sensitivity / hurt feelings 0.4 0.7 2.5 -1.0 -0.4 -0.4 -0.2 1.6 -0.4 -0.3 -0.2 1.1 -0.4 -0.7 -0.3 -0.6 0.2 1.5 -0.1 1.3 0.7 1.6 0.9
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.7 -1.1 0.2 0.6 1.3 0.2 0.5 -1.2 -0.7 -0.0 0.4 0.3 0.5 -0.7 0.8 0.8 0.5 0.8 -0.9 0.9 0.3
Hearing difficulty/problems: Yes 0.3 0.4 1.0 -0.7 0.8 0.6 0.7 0.7 0.7 0.6 0.0 -0.1 0.6 0.5 0.7 -0.5 -0.1 0.9 0.4 0.9 0.7 1.0 1.0
Relative age of first facial hair 0.3 0.7 2.2 -0.5 0.7 0.6 0.8 1.0 0.6 1.2 0.5 0.1 0.6 0.2 0.8 -0.2 -0.0 1.5 0.3 1.3 1.3 1.3 0.8
Other serious medical condition/disability diagnosed by doctor 2.0 2.6 10.7 3.3 -0.3 -1.1 -0.4 -0.6 -1.3 1.4 1.1 0.6 -1.3 -0.9 -1.2 1.6 -1.4 -2.4 -2.4 -2.6 -0.0 -2.2 -1.7
Ever used hormone-replacement therapy (HRT) 0.5 0.6 2.2 1.5 0.1 -0.1 1.5 -0.7 -0.0 0.8 1.2 -0.6 -0.1 0.2 0.0 1.5 -0.3 -1.0 -0.3 -0.9 0.7 -0.8 -0.5
Ever had hysterectomy (womb removed) 0.5 0.6 2.2 1.0 -0.2 -0.5 -0.2 -1.5 -0.5 -0.9 -0.3 0.3 -0.4 -0.2 -0.8 0.5 -1.2 -1.0 -0.8 -0.8 0.4 -1.1 -0.9
Systolic blood pressure, automated reading 0.2 0.7 1.6 -0.7 -1.2 -1.0 -1.2 -0.2 -1.0 0.0 -1.0 1.2 -1.0 -1.1 -0.5 -0.9 -0.1 -0.4 -0.9 -0.5 -1.0 -0.5 -0.2
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 3.0 0.3 -1.2 -0.9 -0.3 -0.0 -0.9 -0.6 -0.0 -0.2 -0.9 -0.6 -0.8 0.1 0.2 -1.7 -0.3 -1.7 -1.7 -1.7 -0.8
Angina 1.2 1.5 3.6 1.2 -1.3 -0.8 0.2 -1.5 -1.4 -0.5 -0.3 0.6 -1.4 -1.2 -1.4 0.8 -1.2 -1.9 -1.4 -1.9 -0.9 -1.6 -1.5
Medication for hormone replacement therapy 0.6 0.7 1.4 0.7 0.7 0.7 0.4 0.8 1.0 0.1 0.9 -1.2 1.0 1.1 0.6 1.1 0.9 0.7 1.0 0.8 0.6 0.6 0.4
Vitamin and mineral supplements 1.5 2.0 5.6 -0.7 0.9 1.3 0.9 2.2 1.2 0.7 0.8 -0.5 1.3 1.1 1.4 -0.6 1.5 2.4 1.4 2.3 0.8 2.2 1.9
Supplements: Zinc 0.8 0.9 2.8 -1.0 -0.4 -0.6 -0.2 -1.5 -0.5 -0.8 -1.7 0.8 -0.5 -0.7 -0.8 -1.7 -1.1 -0.8 -0.6 -0.9 -1.1 -0.8 -0.4
Medication: Co-codamol 0.3 0.4 2.1 0.6 -0.5 -0.6 -0.8 1.4 -0.6 -0.2 0.2 0.7 -0.6 -0.7 -0.7 -0.4 0.3 0.3 -0.5 -0.1 -0.4 0.3 0.4
Medication: Metformin 0.5 0.7 3.5 -1.8 -0.3 -0.1 -0.4 0.1 0.1 -0.8 -1.0 -0.2 0.1 -0.1 -0.0 -1.9 0.9 0.2 0.9 0.1 -1.7 0.3 0.7
Diabetes (father) 0.7 0.9 4.5 -0.3 -1.0 -0.6 -2.1 -0.4 -1.0 -0.6 -1.0 1.1 -1.0 -1.3 -1.1 -0.7 -0.8 -0.5 -0.9 -0.6 -1.2 -0.5 -0.7
Diabetes (mother) 0.4 0.5 2.5 -1.1 -0.0 0.6 -0.1 0.3 0.3 0.5 0.2 -0.1 0.3 -0.1 0.5 -0.2 1.6 1.2 0.7 1.1 0.2 1.2 1.0
Severe depression (siblings) 3.0 3.3 6.4 1.0 -1.7 -2.0 -0.8 -2.0 -2.2 -0.8 -0.3 1.6 -2.2 -2.0 -2.3 0.8 -1.9 -2.2 -2.5 -2.5 -1.2 -2.2 -2.1
Pack years adult smoking proportion 1.5 2.3 4.3 -0.5 -1.7 -1.8 -1.1 -2.1 -1.6 -1.8 -1.5 1.5 -1.6 -1.8 -1.7 -0.5 -2.0 -1.1 -1.4 -1.1 -1.5 -1.3 -1.6
Impedance of leg (right) 0.5 2.5 14.3 3.5 0.3 0.8 -0.2 -0.5 -0.4 0.4 2.7 -0.9 -0.4 0.3 0.1 3.8 -0.3 -1.8 -1.2 -1.6 1.6 -1.7 -1.4
Leg fat-free mass (left) 0.2 1.1 7.0 -2.2 -0.3 -0.0 -0.0 0.5 0.1 -0.6 -1.8 0.7 0.2 -0.4 -0.1 -2.6 0.2 1.2 0.7 1.1 -1.1 1.2 0.8
Trunk fat percentage 2.1 8.3 17.1 1.3 -3.3 -3.1 -3.0 -2.5 -3.7 -0.7 -2.0 2.9 -3.6 -3.5 -2.9 -0.8 -2.0 -2.9 -3.3 -3.4 -4.1 -2.9 -2.8
Hand grip strength (right) 0.3 0.9 3.6 -1.7 0.2 0.4 0.4 0.8 0.7 -1.9 -1.5 0.3 0.7 0.3 0.1 -1.9 -0.3 0.5 0.7 1.0 0.6 0.2 1.1
Townsend deprivation index at recruitment 1.8 2.5 4.5 0.4 -1.7 -2.1 -1.5 -1.9 -1.8 -1.4 -1.6 1.5 -1.8 -1.5 -1.5 -0.5 -1.7 -1.9 -1.5 -1.8 -1.1 -1.9 -1.7
Current tobacco smoking 2.4 4.0 7.2 0.8 -2.2 -2.7 -1.0 -2.6 -2.2 -2.3 -1.4 1.6 -2.2 -2.0 -2.3 0.3 -2.0 -2.2 -1.9 -2.0 -1.6 -2.4 -2.5
Average weekly fortified wine intake 0.8 0.9 2.7 -1.3 0.2 0.6 0.4 1.3 0.7 -0.4 0.1 -0.7 0.7 0.6 1.1 0.0 1.4 1.5 1.5 1.6 -0.0 1.4 0.8
Maternal smoking around birth 0.8 1.1 5.1 0.2 1.1 0.7 0.1 1.2 1.1 2.3 0.9 -0.9 1.1 1.1 1.2 0.1 0.6 1.1 0.9 1.1 1.2 1.1 1.1
Fed-up feelings 1.6 3.0 10.6 -2.6 0.8 1.0 1.1 2.1 1.1 0.3 -0.5 0.3 1.0 0.3 1.2 -1.7 1.6 3.3 1.4 2.9 0.5 3.2 2.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.5 0.4 0.1 0.5 1.0 0.3 0.3 -0.4 0.4 -1.0 0.2 0.5 0.4 0.9 1.1 -0.3 0.5 -0.2 -1.2 -0.0 -0.4
Relative age voice broke 0.4 0.6 2.2 0.1 1.1 0.7 0.8 0.4 0.7 1.5 0.7 -0.3 0.7 0.5 0.6 0.9 0.2 0.9 0.1 0.8 1.4 1.0 0.4
Taking other prescription medications 1.3 2.1 8.6 2.9 -0.8 -1.2 0.0 -0.7 -1.2 0.3 0.8 0.0 -1.2 -0.5 -1.0 1.6 -0.3 -2.3 -1.5 -2.5 -1.1 -2.1 -1.7
Age when periods started (menarche) 1.1 2.7 7.8 -2.6 1.1 1.1 0.4 2.0 1.2 1.3 -1.3 0.2 1.1 0.5 1.7 -2.8 0.7 2.4 1.1 2.4 0.2 2.5 2.2
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.8 0.6 -0.1 -0.1 0.4 -0.6 -0.2 -0.1 -0.3 0.5 -0.2 0.2 -0.2 -0.1 -0.9 -0.5 -0.6 -0.2 0.9 -0.5 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.0 -0.9 -0.2 -0.2 -0.1 0.0 0.0 -0.3 -0.7 0.5 0.0 -0.2 -0.3 -1.0 0.3 0.4 0.1 0.3 0.2 0.3 0.5
Tinnitus: Yes, but not now, but have in the past 3.4 3.6 8.9 -1.9 1.6 1.6 0.8 1.8 1.9 -0.2 -0.3 -0.4 1.9 1.6 1.8 -2.0 1.6 2.8 2.0 3.0 1.7 2.7 2.9
Qualifications: CSEs or equivalent 1.2 1.5 3.9 -0.7 -1.5 -1.6 -2.0 -0.6 -1.6 -0.8 -1.2 2.0 -1.5 -1.9 -1.3 -0.3 -0.8 0.7 -1.1 0.3 -1.1 0.6 -1.1
Serious illness, injury or assault to yourself 1.1 1.3 6.5 2.3 0.2 0.4 0.1 0.9 0.4 1.1 1.7 -1.7 0.3 0.8 0.5 2.5 1.8 -0.5 0.5 -0.6 -0.6 -0.3 -0.8
High blood pressure 0.9 2.5 9.8 -2.1 -2.0 -2.1 -0.6 -1.1 -1.5 -1.1 -2.3 1.4 -1.5 -1.7 -1.7 -1.8 -0.4 -0.7 -0.6 -1.0 -3.1 -0.6 -1.0
Hayfever, allergic rhinitis or eczema 2.4 5.2 9.1 1.2 2.5 2.2 2.6 2.9 2.7 0.8 2.4 -2.8 2.7 3.0 2.7 1.3 2.3 1.4 2.5 1.8 2.4 1.5 2.1
Multivitamins +/- minerals 1.8 2.3 6.3 0.4 -1.0 -1.3 -0.5 -2.3 -1.1 -1.8 -0.9 0.3 -1.1 -0.9 -1.5 0.9 -1.4 -2.5 -1.1 -2.4 -0.9 -2.4 -2.3
Stomach or abdominal pain in last month 0.6 0.8 2.8 1.7 -0.8 -1.2 -0.0 0.1 -1.1 0.2 0.2 0.5 -1.1 -0.9 -0.8 0.8 -0.2 -1.0 -1.2 -1.1 -0.8 -0.9 -1.1
Supplements: Glucosamine 0.8 1.1 3.8 1.3 1.2 0.9 1.5 -0.2 1.1 -0.4 1.1 -2.0 1.1 1.6 0.6 1.3 -0.3 -0.9 0.9 -0.5 0.6 -0.8 -0.2
Diverticular disease/diverticulitis (self-reported) 1.7 2.0 4.9 2.2 -1.6 -1.1 -2.0 -1.0 -1.5 0.4 0.7 0.2 -1.6 -1.0 -0.9 2.0 -0.2 -1.7 -1.2 -1.9 -1.3 -1.6 -1.8
Medication: Atenolol 0.2 0.2 1.0 0.8 -0.2 -0.3 0.0 -1.0 -0.3 0.2 0.4 -0.2 -0.3 -0.1 -0.4 0.8 0.0 -0.6 -0.2 -0.6 0.2 -0.6 -0.5
Medication: Levothyroxine sodium 1.7 3.0 9.4 3.1 1.5 1.2 2.1 0.3 1.2 1.8 2.7 -2.6 1.3 1.9 1.3 2.9 2.4 -0.5 0.8 -0.5 0.1 -0.2 -0.2
Sitting height 0.2 1.4 3.6 -1.4 0.5 1.9 1.2 0.9 1.1 -0.6 0.8 -0.9 1.1 0.9 0.8 0.3 1.6 1.5 1.7 1.6 0.7 1.6 0.9
Chronic bronchitis/emphysema (father) 1.3 1.5 4.0 0.3 -1.9 -2.0 -1.7 -1.1 -1.7 -0.0 0.2 1.4 -1.7 -1.7 -1.1 1.0 -0.3 -0.4 -1.4 -0.6 -0.7 -0.3 -1.2
High blood pressure (mother) 0.4 0.6 2.9 0.7 -0.5 -0.8 0.8 -0.2 -0.6 1.7 1.4 -0.4 -0.5 -0.2 0.0 1.6 0.5 -0.3 -0.2 -0.6 -0.2 -0.2 -0.5
Body mass index (BMI) 1.2 5.1 13.8 -1.5 -2.4 -2.9 -1.8 -1.2 -2.4 -0.8 -3.3 3.0 -2.4 -2.9 -2.1 -3.5 -1.6 -0.7 -1.8 -1.2 -3.7 -0.8 -0.9
Impedance of leg (left) 0.6 2.9 13.8 3.3 -0.5 -0.0 -0.8 -1.3 -1.1 -0.4 2.1 -0.3 -1.1 -0.4 -0.8 3.7 -0.7 -2.3 -1.7 -2.2 0.8 -2.2 -2.0
Leg predicted mass (left) 0.2 1.1 6.7 -2.1 -0.2 0.0 0.0 0.5 0.2 -0.5 -1.7 0.7 0.2 -0.4 -0.0 -2.6 0.3 1.2 0.8 1.0 -1.1 1.2 0.8
Trunk fat mass 1.6 6.7 15.6 0.5 -3.1 -2.8 -2.6 -2.1 -3.3 -1.0 -2.3 2.8 -3.2 -3.3 -2.7 -1.4 -1.8 -2.2 -2.8 -2.7 -3.9 -2.2 -2.3
Waist circumference 1.3 4.8 12.7 -0.4 -2.9 -2.6 -2.1 -1.6 -2.8 -1.1 -2.3 2.6 -2.8 -3.0 -2.2 -1.9 -1.2 -1.2 -2.1 -1.7 -3.6 -1.3 -1.7
Number of incorrect matches in round 2.2 3.6 8.9 -1.5 2.0 1.8 1.5 1.5 2.1 1.3 0.2 -0.9 2.1 1.6 1.8 -1.5 1.9 2.9 1.9 2.7 0.9 3.0 2.6
Past tobacco smoking 3.0 5.4 15.6 -3.1 1.8 2.2 1.2 1.6 2.3 0.2 0.4 -1.0 2.3 1.7 2.4 -0.9 2.5 3.8 2.7 4.0 1.5 3.5 2.6
Alcohol usually taken with meals 1.7 2.8 6.3 -0.6 1.7 2.5 1.7 1.9 2.0 1.2 0.9 -1.5 2.0 2.1 2.1 -0.0 1.3 1.4 1.8 1.7 1.8 1.4 1.8
Nervous feelings 0.2 0.4 1.5 -1.2 -0.8 -0.6 0.0 0.7 -0.6 -1.0 -0.2 1.0 -0.7 -0.8 -0.6 0.1 -0.5 0.3 -0.6 0.2 0.8 0.3 -0.1
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 3.7 -1.8 -0.6 -0.4 0.6 -0.5 -0.2 -1.2 -0.7 0.2 -0.2 -0.4 -0.3 -0.7 1.0 0.6 0.4 0.4 -1.9 0.6 -0.0
Hearing difficulty/problems with background noise 0.2 0.3 0.8 -0.2 0.9 0.7 0.8 0.0 0.7 0.6 -0.1 -0.3 0.7 0.8 0.8 -0.6 -0.4 0.5 0.3 0.5 0.1 0.5 0.7
Hair/balding pattern: Pattern 2 0.1 0.1 0.3 0.1 -0.1 -0.2 0.5 -0.4 -0.0 -0.1 0.0 -0.3 -0.0 0.2 -0.1 0.2 0.2 -0.6 0.1 -0.6 -0.3 -0.4 -0.3
Had menopause 0.9 1.1 3.7 1.9 -0.5 -0.6 0.4 -0.5 -0.9 0.8 0.8 0.0 -0.9 -0.4 -0.9 1.5 -0.5 -1.8 -1.1 -1.6 0.4 -1.6 -0.8
Had other major operations 1.0 1.3 5.4 2.3 0.0 0.5 0.7 -2.1 -0.3 1.8 1.1 -0.2 -0.3 0.3 0.1 1.4 -1.1 -1.3 -1.0 -1.2 1.3 -1.2 -0.4
Forced vital capacity (FVC) 1.4 5.3 10.3 -2.7 2.3 2.5 2.6 1.9 2.5 0.2 -0.1 -1.1 2.6 2.2 2.6 -1.5 0.9 2.9 2.6 3.2 2.6 2.9 2.7
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 3.2 -0.7 -0.7 -0.7 -0.9 -0.1 -0.5 -0.8 -1.6 1.1 -0.6 -0.8 -0.8 -1.8 -0.3 -0.5 -0.6 -0.5 -0.6 -0.7 -0.0
Ever unenthusiastic/disinterested for a whole week 1.2 1.5 3.5 0.3 -1.7 -1.5 -1.2 0.3 -1.8 -0.4 -0.8 1.8 -1.8 -1.8 -1.9 0.1 -0.9 -0.5 -1.8 -0.5 -0.2 -0.5 -0.9
Qualifications: None of the above 0.5 1.0 3.8 -0.3 0.6 0.9 0.8 0.5 0.5 1.0 0.9 0.2 0.4 0.1 0.4 -0.2 1.1 1.9 0.4 1.8 1.4 1.9 1.6
Financial difficulties in last 2 years 1.0 1.3 4.4 1.8 -0.3 -1.1 -0.3 -0.6 -1.1 0.4 0.2 1.2 -1.1 -1.2 -1.0 1.3 -1.5 -1.0 -2.1 -0.9 1.2 -1.0 -1.2
Mouth/teeth dental problems 1.2 1.9 4.4 -1.5 1.4 1.7 0.6 0.7 1.6 -0.2 -0.1 -0.4 1.6 1.3 1.1 -1.0 -0.1 2.0 1.5 2.1 1.9 1.9 1.5
Heart attack 0.6 0.7 4.2 -0.3 -1.0 -0.2 0.7 -0.8 -0.6 -0.9 0.1 -0.7 -0.6 -0.2 -0.6 0.3 0.1 -1.3 0.3 -1.4 -2.0 -1.0 -0.9
Allergy 1.1 2.6 7.3 -2.3 -1.6 -1.0 -1.4 -1.7 -1.6 -0.9 -2.7 2.2 -1.6 -2.0 -1.6 -2.2 -1.8 -0.4 -1.2 -0.5 -1.8 -0.5 -0.8
Pain all over the body in last month 0.2 0.2 1.3 -0.3 0.1 -0.3 -0.3 1.1 -0.0 0.4 -0.6 0.7 -0.0 -0.1 0.3 -0.7 0.2 0.4 -0.4 0.5 0.4 0.3 0.7
Diabetes (self-reported) 0.4 0.7 2.5 -1.4 -0.0 0.1 0.3 0.8 0.4 0.2 -0.1 -0.4 0.4 0.2 0.5 -1.5 1.6 0.9 1.1 0.8 -0.8 1.1 1.2
Hayfever/allergic rhinitis (self-reported) 0.7 1.0 4.8 2.2 0.2 0.9 1.3 0.6 0.3 -0.8 1.6 -1.2 0.2 0.7 0.4 2.0 -0.1 -0.8 0.2 -0.6 0.5 -0.6 -0.9
Medication: Ramipril 0.5 0.7 2.6 -0.2 -0.8 -0.8 -0.9 -0.8 -0.5 -0.6 -1.1 0.1 -0.5 -0.4 -0.7 -0.7 -0.7 -1.1 -0.3 -1.1 -1.6 -1.1 -0.9
Medication: Simvastatin 0.9 1.3 3.5 -0.2 -1.3 -1.3 -0.5 -0.6 -1.0 -1.9 -1.3 0.9 -1.1 -1.0 -1.6 -0.7 -1.0 -1.2 -0.8 -1.3 -1.4 -1.3 -1.1
Fluid intelligence score 2.3 4.7 18.7 2.6 -1.5 -1.3 -1.0 -4.3 -1.7 -1.0 0.2 -0.1 -1.6 -0.6 -1.5 2.2 -1.8 -3.6 -1.7 -3.3 -1.3 -3.4 -2.7
Illnesses of siblings 3.6 5.0 8.3 -1.0 2.6 2.8 1.7 2.3 2.8 1.1 0.8 -2.1 2.9 2.6 2.8 -0.7 2.0 2.3 2.6 2.5 1.7 2.3 2.5
Neuroticism score 0.5 1.0 3.8 -1.9 -1.1 -0.9 -0.1 0.6 -0.7 -1.6 -1.1 1.2 -0.7 -1.0 -0.5 -1.1 0.4 1.1 -0.1 0.8 -1.1 1.1 0.3
Weight 0.4 2.2 7.2 -1.4 -1.8 -1.4 -1.1 -0.6 -1.5 -0.8 -2.2 1.9 -1.5 -2.0 -1.3 -2.5 -0.6 -0.1 -0.8 -0.5 -2.7 -0.1 -0.5
Impedance of arm (right) 0.8 3.9 22.3 3.9 -0.5 0.9 -1.0 -1.3 -0.7 0.1 2.8 -1.6 -0.7 0.3 -0.2 4.7 0.2 -2.7 -0.8 -2.5 -0.2 -2.4 -2.4
Arm fat percentage (right) 1.8 7.3 20.4 0.5 -3.2 -3.1 -2.9 -2.3 -3.3 -1.0 -2.5 2.7 -3.2 -3.2 -2.7 -1.6 -1.8 -2.3 -2.7 -2.8 -4.5 -2.4 -2.5
Trunk fat-free mass 0.4 2.0 6.7 -2.3 0.5 0.8 0.8 1.4 1.0 -0.1 -1.0 0.3 1.0 0.4 0.7 -2.6 0.9 2.3 1.5 2.2 0.4 2.2 1.9
Hip circumference 0.3 1.4 7.3 -1.1 -1.3 -0.9 -1.2 -0.2 -1.1 -0.3 -1.8 1.4 -1.1 -1.6 -0.9 -2.1 -0.1 0.2 -0.5 -0.3 -2.7 0.2 -0.4
Time employed in main current job 0.2 0.3 2.0 0.1 0.3 0.1 -0.2 1.4 0.3 1.1 0.4 -0.2 0.3 0.3 0.3 0.1 0.1 0.5 0.3 0.6 0.5 0.5 0.6
Alcohol intake versus 10 years previously 0.8 1.2 6.9 -2.6 -1.0 -0.6 -1.1 -0.4 -0.5 -0.5 -1.3 1.2 -0.6 -1.4 -0.4 -1.4 0.1 1.3 -0.0 1.0 -1.2 1.2 -0.0
Father’s age at death 0.2 0.3 2.6 0.1 -0.5 -0.2 -0.4 -1.1 -0.4 -1.6 -0.6 -0.0 -0.3 -0.2 -0.3 -0.3 -0.0 -0.7 0.1 -0.4 -0.3 -0.8 -0.3
Worrier / anxious feelings 1.1 2.1 4.2 -1.4 0.8 1.3 2.0 1.6 1.4 -0.5 0.6 -1.3 1.4 1.5 1.9 0.2 2.0 1.6 2.0 1.7 1.0 1.8 1.4
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 5.5 -2.3 -0.6 -0.3 1.3 -0.2 -0.2 -1.4 -1.6 0.9 -0.2 -0.7 -0.5 -2.0 0.6 1.1 0.3 0.8 -1.7 1.0 0.7
Falls in the last year 0.4 0.6 2.9 -0.8 0.2 0.5 1.3 1.7 0.3 -0.2 -0.1 -0.1 0.3 0.1 0.7 -0.8 1.3 0.8 0.5 0.6 -0.5 0.8 0.8
Hair/balding pattern: Pattern 3 0.2 0.4 1.0 -0.3 0.3 0.5 1.0 -0.2 0.6 -0.4 0.7 -0.7 0.6 0.7 0.5 0.4 0.8 0.7 0.9 0.8 0.1 0.5 0.3
Number of live births 0.2 0.3 1.0 -0.1 0.3 0.3 1.0 0.3 0.4 -0.4 -0.2 -0.3 0.5 0.4 0.7 -0.3 0.7 0.7 0.6 0.7 0.2 0.6 0.4
Forced expiratory volume in 1-second (FEV1) 1.6 5.2 9.9 -2.4 2.2 2.8 2.6 1.8 2.5 0.4 0.2 -1.4 2.6 2.1 2.6 -1.1 1.5 2.9 2.7 3.1 2.2 2.9 2.6
Pulse rate 0.9 1.5 3.2 0.3 -1.0 -1.8 -1.6 -0.5 -1.2 -1.0 -1.7 1.1 -1.2 -0.9 -1.0 -1.2 -1.6 -1.5 -1.0 -1.2 -0.8 -1.6 -0.8
Happiness 0.8 1.0 2.9 -1.3 0.9 1.2 0.4 1.0 1.0 -0.8 0.5 -0.5 1.0 0.7 0.5 0.3 0.5 1.7 1.0 1.6 1.0 1.6 0.8
Noisy workplace 1.0 1.2 7.1 1.0 -0.6 -1.2 -2.7 -1.0 -1.2 -0.4 -0.0 1.0 -1.2 -1.1 -1.1 0.9 -1.2 -0.8 -1.4 -0.9 0.3 -0.9 -1.0
Qualifications: A levels/AS levels or equivalent 0.3 0.7 2.0 -0.4 0.5 0.6 1.4 -1.2 0.6 -1.0 -0.4 -1.0 0.6 1.0 0.5 -0.0 -0.7 -1.3 0.6 -0.9 -0.4 -1.4 -0.6
Serious illness, injury or assault of a close relative in last 2 years 2.5 2.8 6.7 2.6 -1.4 -1.2 -1.6 -2.0 -1.9 1.0 -0.1 1.5 -1.9 -1.7 -1.7 1.7 -1.4 -1.9 -2.5 -1.7 0.9 -1.8 -1.8
Mouth/teeth dental problems: Dentures 0.9 1.4 5.5 2.3 -0.6 -0.4 -0.3 -1.0 -0.7 0.6 1.0 -0.7 -0.7 -0.2 -0.5 1.4 0.4 -2.1 -0.8 -2.1 -1.5 -1.9 -1.1
Asthma 0.2 0.4 2.2 1.3 0.2 -0.2 0.1 0.3 0.3 0.3 1.1 -0.4 0.2 0.4 0.3 1.5 0.3 0.2 0.2 0.2 1.2 0.3 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.4 -0.3 0.5 -0.1 0.4 1.0 0.3 0.2 -0.5 0.8 0.3 0.1 0.1 -1.2 -0.6 1.0 -0.2 1.0 1.0 0.8 1.0
Medication: Cholesterol lowering 1.1 1.7 10.6 -0.4 -1.0 -1.0 0.2 -1.1 -0.9 -1.4 -0.9 -0.2 -0.9 -0.7 -1.2 -0.5 -0.2 -2.0 -0.4 -2.2 -3.3 -1.9 -1.3
Depression (self-reported) 0.3 0.3 2.0 -0.5 -0.3 0.3 0.4 -0.7 -0.2 -1.3 -0.3 -0.3 -0.2 -0.1 -0.2 0.3 0.0 -0.6 0.1 -0.6 -1.4 -0.4 -0.8
Medication: Lansoprazole 1.7 1.9 4.6 -0.3 -1.3 -1.3 -0.5 -1.4 -1.5 -0.6 -2.1 1.8 -1.5 -1.6 -1.3 -1.9 -1.3 -1.5 -1.6 -1.4 -1.0 -1.5 -0.5
Prospective memory result 1.0 1.2 6.0 0.8 1.3 0.8 0.2 2.4 0.9 1.9 1.6 -1.2 0.9 1.1 0.9 1.0 0.8 0.3 0.4 0.3 1.1 0.5 0.7
Lung cancer (father) 2.5 3.0 7.1 -0.9 -2.1 -1.9 -2.1 -1.8 -2.2 -1.8 -1.1 2.1 -2.2 -2.7 -2.4 0.2 -1.0 -0.6 -1.7 -0.9 -1.5 -0.7 -1.8
Illnesses of mother 0.7 0.9 1.7 -0.3 1.0 1.0 -0.4 1.1 1.2 -0.6 0.4 -0.8 1.1 1.0 1.0 -0.0 0.9 1.3 1.2 1.3 1.0 1.2 0.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.6 8.6 -2.8 1.5 2.1 1.7 1.3 1.9 0.2 -0.2 -0.6 1.9 1.3 2.0 -1.4 1.1 2.9 2.1 2.9 1.5 2.8 2.2
Pulse wave Arterial Stiffness index 0.4 0.5 1.5 0.8 -0.7 -1.2 -0.5 -0.6 -0.8 0.4 0.5 0.5 -0.9 -0.9 -0.8 1.1 -0.1 -0.4 -0.8 -0.6 -0.0 -0.2 -0.8
Impedance of arm (left) 0.7 3.3 17.1 3.2 -0.5 0.8 -1.1 -1.4 -0.7 0.1 2.2 -1.3 -0.7 0.2 -0.2 4.1 -0.1 -2.7 -1.0 -2.6 -0.1 -2.4 -2.2
Arm fat mass (right) 1.2 4.9 13.7 -0.1 -2.6 -2.7 -2.2 -1.5 -2.7 -0.6 -2.5 2.6 -2.6 -2.8 -2.2 -2.2 -1.4 -1.4 -2.1 -1.9 -3.7 -1.5 -1.6
Trunk predicted mass 0.4 2.1 6.4 -2.3 0.5 0.8 0.9 1.3 1.0 -0.1 -1.0 0.2 1.1 0.4 0.8 -2.5 0.9 2.3 1.5 2.3 0.4 2.2 1.9
Standing height 0.2 2.2 7.7 0.1 1.1 2.8 1.6 1.0 1.5 -0.2 1.8 -1.7 1.5 1.5 1.4 1.6 1.6 1.1 1.8 1.3 1.9 1.3 0.7
Length of working week for main job 0.3 0.3 3.0 0.5 0.2 0.3 -0.5 0.6 0.2 -0.2 1.1 -0.5 0.2 0.1 0.0 1.7 0.4 0.5 0.2 0.5 0.3 0.5 -0.4
Exposure to tobacco smoke at home 0.6 0.7 1.7 -1.2 -1.1 -0.9 -0.8 -0.8 -0.8 -0.7 -1.3 1.2 -0.9 -1.0 -0.8 -0.7 -0.5 -0.0 -0.8 -0.0 -0.9 -0.0 -0.5
Breastfed as a baby 1.9 2.4 5.3 2.0 -1.4 -1.3 -0.6 -2.0 -1.5 -1.5 0.5 0.4 -1.5 -0.9 -1.6 2.0 -0.7 -2.3 -1.3 -2.1 -0.4 -2.3 -2.1
Tense / ‘highly strung’ 0.7 1.1 5.6 -2.4 -0.5 -0.4 0.2 0.8 0.2 -1.3 -1.3 0.6 0.1 -0.2 0.1 -1.8 0.5 1.6 0.7 1.5 -0.4 1.5 0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 3.0 1.5 -0.7 -1.2 -0.1 -0.1 -0.9 -0.3 0.2 0.1 -1.0 -0.4 -0.7 0.5 -0.4 -1.7 -0.9 -1.7 -0.8 -1.5 -0.9
Hair/balding pattern: Pattern 4 0.3 0.7 2.0 1.0 -0.3 -1.2 -0.7 0.8 -0.9 1.2 0.1 0.8 -0.9 -1.0 -0.7 0.3 -0.6 -0.8 -1.4 -1.0 -0.2 -0.7 -0.4
Birth weight of first child 1.4 2.6 6.3 1.1 -2.5 -1.9 -2.0 -1.3 -2.1 -1.3 0.4 1.2 -2.1 -1.9 -2.0 1.6 -0.8 -1.1 -1.5 -1.2 -0.8 -1.3 -2.1
Peak expiratory flow (PEF) 1.7 4.0 7.6 -1.6 2.2 2.0 1.9 2.0 2.4 1.4 0.2 -1.3 2.4 1.9 2.0 -1.4 1.4 2.8 2.3 2.7 1.3 2.6 2.2
Pulse wave reflection index 0.2 0.3 1.2 -0.1 0.2 -0.4 1.1 -0.6 0.2 0.8 0.4 -0.1 0.2 0.1 0.0 0.7 0.2 0.6 0.1 0.5 0.9 0.7 0.1
Ever highly irritable/argumentative for 2 days 0.9 1.1 2.8 1.2 -1.7 -1.3 -1.0 0.8 -1.5 0.4 0.1 1.1 -1.6 -1.4 -1.1 0.8 -0.1 -0.7 -1.5 -0.9 -0.7 -0.6 -0.8
Loud music exposure frequency 0.6 0.7 1.7 0.1 -1.3 -0.9 -1.3 -0.6 -1.0 -1.1 0.1 0.4 -1.0 -0.9 -1.2 1.1 0.4 -0.4 -0.5 -0.5 -0.7 -0.4 -0.9
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.7 -0.2 0.5 0.4 0.8 -1.0 0.7 -1.2 -0.6 -0.8 0.8 0.9 0.4 -0.5 0.0 -0.4 0.9 -0.3 -1.3 -0.4 -0.3
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 2.0 -0.2 -1.0 -1.4 -0.5 0.7 -1.1 0.0 -0.2 1.2 -1.2 -1.4 -1.0 0.7 -0.0 0.0 -1.2 -0.2 0.1 -0.1 -0.9
Blood clot in the leg (DVT) 0.3 0.4 1.5 -0.7 -0.9 -0.8 -0.8 0.2 -0.5 -0.0 0.1 0.4 -0.6 -0.8 -0.8 0.1 0.6 0.4 -0.3 0.1 -1.2 0.4 -0.4
Medication: Paracetamol 0.6 1.0 3.8 -0.8 0.1 -0.2 -0.1 1.3 -0.4 0.6 -1.0 1.9 -0.4 -1.0 -0.4 -1.9 -1.0 1.0 -1.1 0.9 1.1 0.9 1.1
Headache pain in last month 0.4 0.6 2.4 -0.7 -1.0 -1.0 0.1 -0.1 -0.9 -0.1 -0.3 1.5 -1.0 -1.4 -0.8 -0.3 -0.5 0.8 -1.0 0.4 -0.4 0.7 -0.2
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 4.7 0.3 0.6 1.2 -0.9 1.1 0.8 1.0 1.1 -0.3 0.8 0.7 1.2 0.9 1.0 1.8 0.7 1.9 2.2 1.7 1.0
Glaucoma (self-reported) 0.3 0.3 1.6 0.8 0.2 0.4 1.0 -0.6 0.1 1.1 0.8 -0.3 0.1 0.3 0.1 0.8 -0.0 -0.2 -0.2 -0.2 1.3 -0.2 0.4
Gout (self-reported) 3.4 4.7 10.1 -1.1 -2.2 -2.2 -1.9 -1.2 -2.2 -2.4 -3.2 2.6 -2.2 -2.3 -2.1 -2.5 -2.2 -1.9 -2.1 -1.8 -2.5 -2.2 -1.2
Hypothyroidism/myxoedema (self-reported) 1.1 2.1 11.0 3.1 0.2 -0.1 0.7 -0.3 -0.1 1.9 2.5 -1.5 -0.1 0.6 0.2 3.3 1.8 -1.0 -0.2 -1.2 -0.9 -0.7 -1.3
Medication: Amlodipine 1.3 1.8 3.6 -0.1 -1.2 -1.5 1.0 -1.8 -1.4 -0.9 -1.3 1.1 -1.3 -1.2 -1.6 -1.3 -1.1 -1.8 -1.3 -1.8 -1.5 -1.9 -0.7
Medication: Ventolin 100micrograms inhaler 0.5 0.7 4.9 2.2 -0.4 -0.2 -0.1 0.2 -0.3 -0.0 1.2 -0.5 -0.4 0.1 -0.2 2.1 0.7 -0.7 -0.3 -0.7 0.1 -0.6 -0.8
Birth weight 0.7 1.6 3.6 1.9 -1.6 -1.4 -0.8 -0.9 -1.6 0.2 1.1 0.7 -1.6 -1.3 -1.3 1.8 -0.3 -1.2 -1.3 -1.3 0.1 -1.2 -1.5
Chronic bronchitis/emphysema (mother) 0.1 0.2 0.8 -0.5 0.2 0.0 0.0 0.0 0.2 -0.1 -0.6 0.4 0.2 0.1 0.4 -0.9 -0.4 0.5 -0.0 0.6 0.3 0.6 0.1
High blood pressure (siblings) 0.6 0.9 1.5 -0.4 -1.2 -1.0 -0.5 -1.0 -1.1 -1.2 -0.8 1.2 -1.1 -1.1 -1.2 -0.3 -1.1 -0.5 -0.9 -0.6 -0.9 -0.6 -0.8
Forced vital capacity (FVC), Best measure 1.2 4.4 10.3 -3.2 1.8 2.1 1.7 1.8 2.1 0.0 -0.5 -0.4 2.2 1.6 2.2 -1.9 0.6 3.1 2.2 3.2 2.0 3.0 2.5
Body fat percentage 2.1 8.3 18.3 1.1 -3.2 -3.2 -3.1 -2.5 -3.6 -0.8 -2.2 2.9 -3.6 -3.5 -2.9 -1.1 -2.1 -2.8 -3.2 -3.3 -4.3 -2.8 -2.8
Leg fat percentage (right) 1.6 5.8 11.2 1.1 -2.4 -2.7 -2.3 -2.1 -3.0 -0.4 -1.9 2.6 -2.9 -2.9 -2.4 -1.3 -2.2 -2.2 -2.9 -2.8 -3.3 -2.3 -2.2
Arm fat-free mass (right) 0.4 1.9 9.9 -2.8 0.1 0.1 0.8 0.8 0.5 -0.5 -1.8 1.0 0.5 -0.3 0.2 -3.1 0.1 1.9 0.8 1.8 0.0 1.8 1.5
Exposure to tobacco smoke outside home 0.3 0.4 0.9 -1.0 0.8 0.3 0.6 0.5 0.6 0.8 0.4 -0.5 0.6 0.3 0.6 0.2 0.9 0.9 0.4 0.6 -0.3 0.9 0.4
Comparative body size at age 10 1.4 3.9 9.8 -0.7 -1.6 -2.5 -0.5 -2.0 -1.7 -1.1 -3.1 2.0 -1.7 -1.7 -2.0 -2.7 -2.7 -1.8 -1.6 -2.0 -2.6 -1.9 -1.3
Number of full brothers 1.4 1.8 5.3 2.1 1.7 1.4 1.0 0.5 1.1 0.7 2.3 -1.1 1.1 1.1 1.0 2.2 0.5 0.9 0.4 0.9 2.2 1.0 0.4
Worry too long after embarrassment 0.1 0.1 0.8 -0.6 -0.2 0.0 0.9 0.0 -0.0 -0.8 -0.2 -0.1 0.0 0.2 0.1 0.1 0.5 0.2 0.4 0.3 -0.3 0.2 -0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 0.8 0.4 0.3 0.2 0.9 0.3 0.2 -0.5 0.4 -0.6 0.2 0.3 -0.2 0.7 0.5 -0.1 0.1 -0.2 -0.9 -0.0 -0.4
Wheeze or whistling in the chest in last year 0.7 1.3 4.4 1.1 0.8 0.6 1.8 1.8 0.6 0.5 2.1 -1.0 0.6 0.6 0.7 2.1 1.9 0.8 0.5 0.7 0.6 0.9 0.2
Number of children fathered 0.5 0.6 4.9 1.3 -0.3 -0.7 0.3 -0.6 -0.4 2.2 0.9 0.5 -0.4 -0.4 0.2 0.5 0.0 0.6 -0.6 0.3 0.4 0.7 0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 1.5 1.2 0.6 0.3 0.4 -0.5 0.5 1.2 1.1 -1.2 0.5 1.0 0.7 1.1 0.2 -1.0 0.3 -0.8 0.7 -0.9 -0.1
Age at first live birth 0.9 1.5 4.2 -0.7 -1.0 -0.1 -0.6 -1.0 -0.9 -2.1 -1.7 1.2 -0.9 -0.9 -1.1 -1.9 -1.7 -1.5 -1.1 -1.4 -0.7 -1.7 -0.6
Pulse wave peak to peak time 0.9 1.1 3.5 -0.7 1.2 1.9 1.1 0.9 1.4 -0.3 0.0 -1.0 1.4 1.4 1.3 -0.9 0.5 0.7 1.3 1.0 0.5 0.6 1.1
Health satisfaction 0.3 0.4 2.6 0.9 0.6 -0.1 0.8 1.1 0.2 1.6 0.8 -0.2 0.2 0.2 0.5 -0.2 0.3 0.4 -0.1 0.3 0.0 0.6 0.7
Shortness of breath walking on level ground 0.3 0.4 1.0 0.9 -0.3 -0.5 -0.1 -0.1 -0.5 -0.1 -0.4 0.5 -0.5 -0.4 -0.7 -0.4 -1.0 -0.8 -0.9 -0.9 -0.5 -1.0 -0.5
Qualifications: College or University degree 1.3 4.0 12.6 0.6 -1.5 -1.6 -0.8 -2.3 -1.7 -1.5 -1.3 1.0 -1.7 -1.1 -1.8 0.1 -3.0 -3.4 -1.8 -3.1 -1.0 -3.5 -2.4
Eye problems/disorders: None of the above 0.6 0.7 2.8 -1.7 -0.3 -0.3 -0.6 0.1 -0.2 -0.9 -1.4 1.0 -0.1 -0.5 -0.0 -1.1 -0.4 1.4 0.1 1.3 -0.6 1.2 -0.1
Mouth/teeth dental problems: Loose teeth 0.8 1.0 4.4 -0.6 -0.9 -1.2 -0.7 -0.9 -0.9 -0.1 -1.3 0.6 -0.9 -0.7 -0.8 -0.8 -0.6 -1.2 -0.8 -1.3 -2.1 -1.2 -0.8
Emphysema/chronic bronchitis 1.1 1.2 3.6 1.3 0.8 1.1 0.8 0.8 1.0 0.7 1.7 -1.6 1.0 1.3 1.5 1.3 1.9 0.4 1.0 0.4 0.5 0.5 0.4
Medication for pain relief, constipation, heartburn 0.5 0.9 3.0 -0.3 0.6 1.4 0.5 -0.3 1.1 -0.8 0.8 -1.7 1.1 1.3 1.2 1.3 1.1 0.3 1.5 0.5 0.2 0.2 -0.0
Neck or shoulder pain in last month 0.8 1.1 2.4 0.8 1.0 0.8 1.6 1.2 1.0 1.1 1.1 -0.9 1.0 1.1 1.2 0.1 1.4 1.1 0.9 1.1 0.3 1.2 1.0
Medication: Blood pressure 0.4 0.7 4.3 -0.5 0.0 -0.9 0.9 -0.6 -0.3 -0.4 -1.0 0.1 -0.3 -0.3 -0.6 -1.3 -0.7 -1.1 -0.3 -1.3 -2.1 -1.0 -0.4
Angina (self-reported) 1.4 1.9 4.2 1.3 -1.5 -1.0 0.1 -1.5 -1.6 -0.6 -0.2 0.7 -1.6 -1.3 -1.7 0.9 -1.3 -2.0 -1.4 -2.0 -1.0 -1.7 -1.7
Migraine (self-reported) 1.2 1.5 11.8 -2.0 -0.4 -0.6 -0.0 0.6 -0.3 -1.0 -2.4 1.4 -0.3 -0.7 -0.4 -3.4 -0.8 0.3 -0.2 0.3 -1.1 0.1 1.0
Medication: Ibuprofen 0.8 0.9 2.9 0.5 1.3 0.4 1.2 1.2 1.0 1.1 0.5 -0.1 1.0 0.9 0.8 -0.7 -0.1 0.9 0.2 1.0 1.7 0.9 1.4
Medication: Allopurinol 2.5 3.3 8.0 -1.6 -1.5 -1.7 -1.7 -1.2 -1.6 -1.6 -2.8 2.4 -1.7 -1.8 -1.5 -2.8 -2.2 -1.5 -1.9 -1.4 -1.8 -1.7 -0.6
Medication: Omeprazole 0.7 0.8 3.7 1.7 -0.2 -0.5 -0.0 1.1 -0.2 1.5 1.9 -0.6 -0.2 0.0 -0.1 1.9 1.3 0.3 -0.0 -0.0 -0.2 0.4 -0.3
Medication: Seretide 50 evohaler 1.2 1.3 3.4 0.6 1.3 1.8 1.2 0.8 1.3 -0.3 1.6 -1.4 1.3 1.4 1.1 1.3 1.1 0.6 1.0 0.8 1.6 0.6 0.6
Mean time to correctly identify matches 0.7 1.3 3.8 1.9 -0.8 -0.5 -0.8 -1.3 -1.1 0.5 1.1 0.2 -1.2 -0.9 -1.0 1.7 -0.5 -1.3 -1.2 -1.6 -0.4 -1.1 -1.5
Heart disease (mother) 1.6 2.0 5.3 -0.3 -2.0 -1.6 -1.9 -0.5 -1.8 -1.6 -1.0 1.4 -1.7 -1.9 -1.8 -0.1 -0.6 -0.6 -1.0 -1.0 -2.3 -0.7 -1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.3 0.5 0.1 -0.3 0.6 -0.4 0.1 0.3 0.4 -0.3 0.2 0.2 -0.1 0.2 -0.2 -0.2 0.2 -0.2 0.1 -0.3 0.0
Whole body fat mass 1.4 5.8 15.2 0.1 -2.9 -2.7 -2.4 -2.0 -3.0 -1.0 -2.4 2.7 -2.9 -3.1 -2.5 -1.8 -1.6 -1.8 -2.4 -2.4 -3.9 -1.9 -2.0
Leg fat mass (right) 1.2 4.6 11.0 -0.0 -2.3 -2.5 -2.0 -1.6 -2.6 -0.9 -2.4 2.6 -2.5 -2.7 -2.2 -2.2 -1.8 -1.5 -2.3 -2.0 -3.3 -1.6 -1.6
Arm predicted mass (right) 0.4 1.9 10.9 -2.9 -0.0 -0.1 0.5 0.9 0.3 -0.7 -2.1 1.1 0.4 -0.4 0.0 -3.3 0.0 1.8 0.8 1.7 -0.2 1.7 1.4
Pulse rate, automated reading 1.1 3.5 8.2 0.9 -1.6 -2.4 -2.1 -1.5 -2.0 -0.6 -1.7 1.2 -2.0 -1.6 -1.5 -0.7 -1.8 -2.9 -1.7 -2.7 -1.9 -2.8 -1.7
Alcohol intake frequency. 0.2 0.4 1.9 -1.2 -0.5 0.2 -0.4 -0.5 -0.2 -0.1 -0.1 0.6 -0.2 -0.7 -0.2 0.1 0.6 1.4 0.0 1.2 0.1 1.3 0.1
Comparative height size at age 10 0.1 0.3 1.7 0.3 0.0 0.7 0.7 0.4 0.3 -0.8 0.7 -0.5 0.3 0.4 0.1 0.8 0.4 0.2 0.6 0.4 1.3 0.2 -0.1
Number of full sisters 0.6 0.7 2.2 0.8 -0.3 -0.5 -1.5 -1.1 -0.9 0.7 -0.2 1.5 -0.9 -1.0 -0.7 0.0 -0.9 -0.1 -1.5 -0.3 0.5 -0.2 -0.4
Suffer from ‘nerves’ 0.7 1.2 4.9 -2.2 -0.2 -0.1 1.8 1.2 0.4 -2.2 -1.4 0.2 0.4 0.2 -0.1 -1.9 -0.1 0.6 0.8 0.7 -0.1 0.5 1.0
Overall health rating 0.5 1.0 4.1 0.8 -1.0 -2.0 0.0 0.2 -1.3 0.4 -0.1 1.1 -1.3 -1.2 -1.2 0.2 -0.8 -0.6 -1.6 -0.9 -1.0 -0.6 -1.0
Chest pain or discomfort 0.9 1.4 5.4 2.3 -0.9 -1.4 -0.6 -0.6 -1.3 0.9 0.0 1.1 -1.4 -1.1 -0.9 0.3 -1.0 -1.2 -1.9 -1.3 -0.5 -1.1 -1.1
Had major operations 0.7 0.8 3.3 0.1 0.2 0.7 1.8 0.7 0.6 0.3 0.8 -1.1 0.5 0.7 0.9 0.9 1.6 0.9 1.1 0.9 0.1 1.0 0.7
Age at last live birth 0.3 0.4 1.5 0.4 -0.8 -0.3 -0.8 0.3 -0.5 -1.2 -0.2 0.1 -0.4 -0.3 -0.5 0.4 0.3 -0.9 -0.3 -0.7 -0.6 -1.0 -0.7
Family relationship satisfaction 1.3 1.6 3.4 -0.2 1.0 1.6 0.4 1.0 1.2 0.6 1.8 -1.2 1.2 1.0 1.2 1.7 1.4 1.8 1.1 1.5 1.4 1.8 0.6
Leg pain on walking 0.2 0.2 1.3 0.5 0.1 -0.2 0.2 1.1 -0.0 0.5 0.4 0.2 0.0 -0.0 0.6 0.2 0.5 0.6 -0.1 0.5 0.9 0.5 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 1.3 -0.6 -0.0 -0.2 -0.7 0.3 0.3 -0.4 0.4 -0.7 0.3 0.2 0.6 0.6 1.1 0.4 0.7 0.1 -1.1 0.5 -0.4
Commuting to job workplace: Car/motor vehicle 0.3 0.3 1.7 1.3 0.1 -0.1 -0.5 0.1 -0.3 1.2 0.9 0.0 -0.3 -0.1 0.3 0.8 -0.0 -0.1 -0.6 -0.2 0.6 -0.0 -0.3
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 9.1 -1.6 0.3 0.1 -0.1 0.0 0.3 -0.2 -1.4 0.4 0.4 0.3 0.4 -3.0 -1.3 -0.1 0.4 -0.0 -0.5 -0.2 1.2
Medication: Aspirin 0.2 0.3 1.0 0.3 -0.0 0.1 0.5 -0.1 0.1 -0.8 0.2 -0.9 0.2 0.3 -0.4 0.3 0.4 -1.0 0.4 -1.0 -0.9 -0.7 -0.6
Supplements: Vitamin C 0.3 0.4 1.2 0.7 -0.3 -0.5 -0.5 -1.1 -0.7 1.0 0.4 0.6 -0.7 -0.6 -0.4 0.4 -0.5 -0.4 -1.0 -0.5 -0.1 -0.2 -0.4
Knee pain experienced in last month 0.3 0.5 1.7 -1.0 0.2 0.5 0.8 0.6 0.4 0.1 -0.1 0.2 0.4 -0.1 0.3 -0.4 0.8 1.3 0.5 1.3 0.4 1.2 0.8
Hypertension (Self-reported) 0.6 1.8 8.5 -1.7 -1.7 -1.7 -0.2 -1.0 -1.2 -1.0 -1.8 1.0 -1.2 -1.4 -1.5 -1.6 -0.0 -0.7 -0.4 -1.0 -2.9 -0.7 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 4.5 -1.8 -0.2 -0.4 1.5 0.4 0.1 -0.4 -1.4 0.3 0.1 -0.2 0.4 -2.1 0.2 0.3 0.5 0.2 -1.2 0.2 0.9
Illnesses of father: Heart disease 0.1 0.1 0.7 0.4 0.3 0.1 0.6 0.6 0.2 0.1 -0.1 -0.0 0.3 0.5 0.1 -0.8 -0.5 -0.2 0.0 -0.3 0.1 -0.1 0.2
Illnesses of siblings: Diabetes 1.0 1.2 2.8 -0.1 -1.0 -1.3 -0.4 -1.2 -1.1 -0.7 -1.4 0.9 -1.1 -1.0 -1.3 -0.8 -0.6 -1.6 -1.0 -1.7 -1.1 -1.6 -0.8
Smoking status: Previous 1.7 2.5 8.8 2.2 -1.2 -1.2 -1.0 -0.9 -1.4 0.0 -0.1 0.4 -1.5 -1.0 -1.8 1.0 -1.4 -2.7 -1.6 -3.0 -1.2 -2.4 -1.9
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.9 0.8 0.9 1.3 -0.2 0.3 0.9 0.1 2.2 -1.2 0.9 0.9 1.0 2.0 1.7 1.2 0.9 1.2 1.0 1.0 0.1
Whole body fat-free mass 0.3 1.7 7.3 -2.5 0.2 0.4 0.6 1.0 0.7 -0.3 -1.4 0.5 0.7 0.0 0.4 -2.7 0.7 2.0 1.3 1.9 -0.2 1.9 1.5
Leg fat-free mass (right) 0.2 1.2 6.7 -2.4 -0.4 -0.1 -0.0 0.4 0.2 -0.8 -1.9 0.6 0.2 -0.4 -0.2 -2.6 0.3 1.2 0.9 1.1 -1.3 1.2 0.8
Arm fat percentage (left) 1.9 7.5 20.1 0.1 -3.1 -3.1 -2.9 -2.4 -3.2 -1.1 -2.9 2.7 -3.2 -3.2 -2.6 -1.9 -2.1 -2.4 -2.7 -2.9 -4.5 -2.5 -2.4
Average weekly red wine intake 0.2 0.3 1.5 0.9 -0.3 -0.1 0.0 0.2 0.1 0.8 0.8 -0.7 0.1 0.5 0.5 1.2 0.9 -0.4 0.4 -0.2 0.0 -0.4 -0.3
Handedness (chirality/laterality): Left-handed 0.8 1.0 2.1 0.2 1.2 1.1 1.1 1.3 1.2 1.4 0.2 -1.1 1.2 1.4 1.1 -0.5 0.8 0.4 1.0 0.5 0.9 0.5 1.3
Mood swings 0.6 1.1 3.9 -1.3 0.0 0.5 1.1 1.5 0.4 -0.4 0.7 -0.1 0.3 -0.1 0.3 0.3 1.9 2.0 0.7 1.6 -0.1 1.9 0.8
Loneliness, isolation 0.2 0.2 0.7 -0.3 -0.1 0.2 0.8 0.5 -0.1 -0.8 0.4 0.4 -0.2 -0.4 -0.1 0.6 0.4 0.7 -0.2 0.7 0.8 0.7 0.2
Long-standing illness, disability or infirmity 1.2 1.8 4.2 2.0 -0.9 -1.8 -0.2 -0.0 -1.3 -0.0 0.0 0.8 -1.4 -1.1 -1.4 0.8 -0.9 -2.0 -1.8 -2.0 -0.7 -2.0 -1.5
Ever had bowel cancer screening 1.8 2.1 4.1 2.0 -1.1 -1.9 -1.4 -1.3 -1.6 1.1 0.2 0.8 -1.7 -1.3 -1.2 1.2 -0.8 -1.9 -1.8 -1.9 -0.6 -1.8 -1.8
Diabetes diagnosed by doctor 0.2 0.3 1.3 -0.7 -0.9 -0.6 -0.3 -0.6 -0.6 -0.1 -0.3 0.2 -0.5 -0.6 -0.5 -0.9 0.8 -0.4 0.0 -0.5 -1.2 -0.2 0.1
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.5 0.3 -0.4 0.2 0.7 -0.4 -0.1 -0.2 -0.2 -0.5 -0.2 0.0 0.3 0.6 0.1 -0.6 0.1 -0.4 -0.6 -0.5 -0.7
Friendships satisfaction 0.4 0.5 2.9 -0.3 -0.0 0.4 1.0 0.7 0.2 -0.7 0.8 -0.4 0.2 0.1 0.1 1.7 0.1 0.9 0.4 0.9 0.9 0.8 -0.2
Qualifications: nursing, teaching 0.6 0.9 3.5 0.6 -0.3 -0.3 0.1 -1.9 -0.2 -0.7 -0.3 -0.6 -0.2 0.2 0.1 0.0 -0.3 -1.8 -0.1 -1.7 -1.3 -1.8 -1.1
Commuting to job workplace: Walk 2.5 2.7 10.7 -0.7 -1.6 -1.5 -0.5 -3.3 -1.7 -0.6 -1.4 1.5 -1.7 -1.8 -2.1 -0.6 -1.5 -1.8 -1.6 -2.0 -1.8 -1.7 -1.5
Eye problems/disorders: Cataract 0.3 0.4 1.6 0.2 -0.2 0.3 0.9 -0.4 -0.1 -0.7 -0.5 -0.3 -0.2 -0.0 -0.4 -0.4 -0.1 -1.1 0.0 -1.0 -1.3 -1.0 -0.4
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 1.1 0.1 -0.1 -0.4 0.7 0.4 -0.2 0.2 -0.7 0.2 -0.2 -0.3 -0.1 -0.9 0.2 -0.5 -0.3 -0.5 -1.0 -0.5 0.3
Medication for cholesterol 0.2 0.3 0.9 0.2 0.3 -0.2 0.1 -0.3 -0.2 0.4 -0.6 0.4 -0.3 -0.2 0.2 -0.5 -0.9 -0.9 -0.9 -0.9 -0.2 -0.9 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.6 1.2 -0.5 -1.1 -0.3 -0.0 -0.9 -0.2 -0.1 0.8 -1.0 -1.0 -1.0 0.5 -0.6 -0.9 -1.3 -0.9 0.1 -0.9 -1.1
Back pain experienced in last month 3.1 4.5 10.9 0.2 1.9 1.7 1.3 3.2 1.8 2.4 2.3 -1.5 1.7 1.5 2.2 1.0 3.3 2.7 1.9 2.6 1.3 2.9 2.3
Mineral and other dietary supplements 0.3 0.4 1.5 -0.1 -0.6 0.1 -0.3 0.3 -0.7 0.6 0.1 1.2 -0.7 -1.0 -0.1 0.0 0.1 1.0 -0.8 0.8 0.7 0.9 0.2
Breast cancer (self-reported) 2.0 2.4 4.5 0.5 2.0 1.9 2.1 1.5 1.8 1.8 1.8 -1.8 1.8 1.8 1.9 0.4 1.2 1.0 1.6 1.0 1.3 1.2 1.4
Asthma (self-reported) 0.3 0.6 2.9 1.4 0.4 0.1 0.1 0.6 0.5 0.4 1.4 -0.8 0.4 0.7 0.6 1.7 0.8 0.3 0.4 0.3 1.2 0.4 -0.0
Osteoporosis (self-reported) 0.2 0.2 1.8 -0.6 0.3 -0.1 -0.4 1.3 0.5 -0.6 -0.2 -0.4 0.5 0.4 0.3 -0.6 0.3 0.3 0.7 0.3 -0.3 0.1 0.2
Osteoarthritis (self-reported) 0.3 0.4 2.8 0.5 0.5 0.1 1.7 -0.2 0.2 -0.4 -0.5 -0.3 0.2 0.3 -0.0 -0.6 -0.5 -1.0 -0.1 -0.7 -0.0 -1.1 0.1
Medication: Aspirin 0.3 0.3 1.1 0.3 0.1 0.2 0.8 -0.3 0.1 -0.9 0.3 -0.9 0.1 0.3 -0.4 0.2 0.3 -1.0 0.4 -1.0 -0.8 -0.8 -0.5
Medication: Gliclazide 0.1 0.1 0.5 0.3 0.0 -0.0 -0.3 -0.1 -0.0 0.0 0.3 -0.2 -0.0 0.0 -0.4 -0.3 0.1 -0.5 -0.0 -0.7 -0.7 -0.4 -0.2
Illnesses of father: None of the above (group 1) 1.6 2.0 3.9 0.9 2.0 1.6 1.7 1.2 1.6 1.7 1.4 -1.7 1.6 1.6 2.0 0.6 1.4 0.6 1.1 0.9 1.3 0.6 1.4
Smoking status: Current 2.6 4.1 7.7 0.9 -2.2 -2.8 -1.0 -2.8 -2.3 -2.2 -1.3 1.6 -2.3 -2.0 -2.3 0.4 -2.0 -2.2 -2.1 -2.1 -1.5 -2.4 -2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 2.9 -0.4 1.2 1.0 1.3 0.2 0.9 1.7 0.8 -0.7 1.0 0.9 1.0 -0.3 0.7 1.3 0.9 1.0 0.5 1.5 1.2
Whole body water mass 0.3 1.7 7.6 -2.4 0.1 0.4 0.5 1.0 0.6 -0.3 -1.4 0.5 0.7 -0.0 0.4 -2.8 0.6 2.0 1.2 1.9 -0.2 1.9 1.5
Leg predicted mass (right) 0.2 1.3 6.9 -2.4 -0.3 -0.0 -0.0 0.4 0.2 -0.8 -1.9 0.6 0.2 -0.3 -0.1 -2.6 0.3 1.3 0.9 1.1 -1.3 1.2 0.8
Arm fat mass (left) 1.2 4.8 13.3 -0.6 -2.6 -2.6 -2.1 -1.5 -2.6 -0.8 -2.8 2.7 -2.5 -2.8 -2.1 -2.5 -1.5 -1.2 -2.0 -1.7 -3.7 -1.3 -1.4
Number of self-reported non-cancer illnesses 0.7 1.2 4.1 1.4 -1.4 -1.4 -0.1 -0.3 -1.3 0.7 0.9 0.2 -1.4 -1.0 -1.0 1.2 1.0 -0.7 -0.9 -1.1 -2.0 -0.6 -1.4
Average weekly champagne plus white wine intake 1.1 1.5 3.2 1.7 -1.2 -1.7 -1.3 -0.5 -1.2 -0.1 -0.2 0.4 -1.2 -0.6 -1.1 1.2 -1.2 -1.7 -1.0 -1.4 -0.3 -1.8 -1.6
Miserableness 0.1 0.2 1.3 -0.2 -0.2 0.0 0.7 -0.1 -0.4 -1.1 -0.9 0.5 -0.4 -0.4 -0.4 -0.6 -0.1 -0.2 -0.4 -0.1 -0.3 -0.3 -0.0
Guilty feelings 1.4 2.1 11.5 -3.4 -0.2 0.3 0.7 1.1 0.4 -1.4 -2.2 1.1 0.3 -0.5 0.2 -2.7 0.4 1.9 0.6 1.8 -0.9 1.7 1.4
Wears glasses or contact lenses 1.3 1.5 7.9 2.8 0.1 -0.4 0.3 -0.9 -0.7 1.0 1.2 -0.1 -0.7 0.1 -0.2 1.6 -1.1 -2.0 -1.3 -1.7 1.1 -1.8 -0.8
Ever taken oral contraceptive pill 0.3 0.4 1.2 0.8 0.1 -0.3 -1.0 0.9 -0.3 1.1 0.5 0.7 -0.3 -0.5 -0.3 0.3 -0.5 0.3 -1.0 0.1 1.0 0.2 0.1
Hearing aid user 0.3 0.3 1.0 0.5 0.5 0.5 0.4 0.4 0.3 0.6 -0.3 -0.6 0.4 0.6 0.6 -0.7 0.7 -0.8 0.2 -0.5 -1.0 -0.6 0.5
Mother’s age at death 0.1 0.1 0.8 -0.7 0.4 0.5 0.9 -0.0 0.2 0.3 -0.1 -0.1 0.2 0.1 0.1 -0.7 -0.1 0.2 0.2 0.0 -0.2 0.2 0.3
Financial situation satisfaction 0.9 1.1 3.3 0.4 0.8 1.1 1.2 0.8 0.7 0.7 1.7 -0.6 0.7 0.5 0.4 1.8 0.8 1.4 0.4 1.2 1.5 1.5 0.3
Tinnitus: Yes, now most or all of the time 4.9 5.8 12.4 0.6 -2.7 -2.9 -2.4 -3.5 -2.6 -1.6 -2.1 1.9 -2.7 -2.4 -2.5 -1.0 -2.0 -2.6 -2.0 -2.8 -3.0 -2.5 -2.4
Commuting to job workplace: Public transport 0.1 0.2 0.7 0.3 0.3 0.4 0.5 0.2 0.5 -0.2 0.4 -0.5 0.5 0.5 0.3 0.8 0.1 0.3 0.5 0.2 0.3 0.4 0.0
Eye problems/disorders: Glaucoma 0.1 0.1 0.3 -0.1 -0.2 -0.2 0.3 -0.1 -0.2 0.5 -0.0 0.4 -0.2 -0.4 -0.2 -0.5 -0.1 0.3 -0.3 0.1 0.4 0.2 0.6
Medication: Blood pressure 0.2 0.3 1.2 -0.7 -1.1 -0.3 -0.2 -1.1 -0.5 -0.8 -0.0 -0.1 -0.4 -0.4 -0.7 0.2 0.6 -0.1 0.5 -0.2 -0.8 -0.1 -0.5
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.1 1.0 0.2 -0.2 1.2 0.4 -0.1 1.5 1.3 -0.4 -0.0 0.0 -0.2 0.6 0.8 -0.5 -0.4 -0.7 -0.0 -0.4 0.3
Supplements: Fish oil (including cod liver oil) 0.2 0.3 1.5 -1.2 -0.2 -0.7 -0.7 0.9 0.1 -0.9 -0.6 -0.1 0.1 -0.1 -0.4 -0.3 -0.2 0.0 0.4 0.1 -0.6 -0.0 -0.2
High cholesterol (Self-reported) 0.3 0.6 3.1 -0.8 -0.5 -0.5 0.1 -0.2 -0.4 -1.5 -0.7 0.3 -0.4 -0.6 -0.9 -0.4 -0.5 -0.4 -0.3 -0.8 -1.8 -0.5 -1.0
Medication: Bendroflumethiazide 0.2 0.3 1.1 -1.0 0.0 0.1 0.5 0.7 0.4 -0.4 -0.6 -0.1 0.5 0.4 0.1 -0.9 0.1 0.6 0.8 0.7 0.1 0.6 0.7
Medication: Paracetamol 0.3 0.5 2.0 -0.2 -0.1 -0.1 0.3 1.3 -0.4 0.7 -0.1 1.4 -0.5 -0.8 -0.1 -1.0 -0.4 0.9 -0.9 0.6 0.7 0.8 0.8
Medication: Lisinopril 2.2 2.8 7.2 -2.3 -1.7 -1.7 -0.6 -2.7 -1.6 -1.0 -2.1 1.6 -1.6 -1.9 -1.7 -1.6 -1.8 -1.0 -1.1 -1.3 -2.4 -1.1 -1.1
Medication: Atorvastatin 0.6 0.7 5.6 -0.8 -0.3 -0.1 1.2 -1.5 -0.4 0.2 -0.1 -0.4 -0.3 -0.3 -0.1 -0.5 0.5 -0.8 0.1 -1.2 -2.4 -0.6 -0.5
Illnesses of father: High blood pressure 1.9 2.3 3.9 0.6 -1.5 -2.0 -1.1 -1.5 -1.8 -1.3 -0.7 1.4 -1.8 -1.7 -1.8 0.7 -1.7 -1.7 -1.8 -1.9 -0.2 -1.7 -1.8
Alcohol drinker status: Never 0.2 0.2 1.2 -0.5 0.0 0.2 -0.7 -0.5 -0.1 0.0 -0.3 0.7 -0.1 -0.3 0.0 0.1 -0.6 0.4 -0.5 0.6 1.1 0.3 0.1
Ever smoked 1.6 2.8 7.8 1.8 -1.4 -1.7 -0.1 -1.1 -1.6 -1.0 -0.9 0.7 -1.6 -1.2 -1.6 -0.2 -2.0 -2.8 -1.7 -2.8 -1.4 -2.7 -1.7
Basal metabolic rate 0.2 1.3 7.2 -2.2 -0.3 -0.0 0.2 0.7 0.2 -0.5 -1.6 0.8 0.2 -0.4 0.0 -2.7 0.4 1.5 0.8 1.3 -0.9 1.4 1.0
Leg fat percentage (left) 2.4 8.6 15.6 0.9 -3.1 -3.4 -2.9 -2.7 -3.6 -1.1 -2.5 3.2 -3.5 -3.5 -3.1 -1.5 -2.7 -2.6 -3.4 -3.2 -4.0 -2.8 -2.7
Arm fat-free mass (left) 0.3 1.6 7.1 -2.1 0.1 0.2 0.7 1.1 0.4 -0.1 -1.2 0.8 0.5 -0.2 0.3 -2.7 0.6 2.1 1.0 1.9 -0.1 2.0 1.6
Number of operations (self-reported) 0.6 0.9 1.9 1.4 -1.2 -0.8 0.3 -1.2 -1.2 0.5 0.6 0.4 -1.3 -0.9 -0.8 1.3 -0.5 -1.1 -1.1 -1.3 -0.3 -1.0 -1.1
Average weekly beer plus cider intake 3.2 4.6 7.7 -0.4 -2.5 -2.6 -2.6 -2.6 -2.5 -2.1 -1.7 2.2 -2.6 -2.8 -2.7 -0.2 -1.8 -1.9 -2.1 -1.9 -1.5 -2.0 -2.1
Irritability 0.9 1.5 5.6 -1.9 -1.8 -1.6 -0.8 0.1 -1.3 -2.0 -1.3 1.2 -1.3 -1.4 -1.0 -1.2 -0.1 -0.0 -0.3 -0.3 -2.4 -0.1 -0.5
Risk taking 0.4 0.6 2.1 0.4 -0.8 -1.2 0.0 -1.4 -0.9 -0.1 0.3 0.6 -0.9 -1.1 -0.9 1.0 0.1 -0.5 -0.9 -0.6 -0.4 -0.5 -0.9
Ever had prostate specific antigen (PSA) test 1.9 2.2 3.6 1.2 -1.6 -1.7 -0.9 -1.0 -1.7 -0.9 -1.3 1.4 -1.7 -1.3 -1.8 -0.6 -1.4 -1.8 -1.6 -1.7 -1.6 -1.9 -1.3
Fractured/broken bones in last 5 years 1.0 1.3 2.9 1.1 -1.0 -1.3 -1.4 -0.9 -1.4 0.7 -0.3 1.3 -1.4 -1.1 -0.9 0.1 -1.4 -1.3 -1.7 -1.2 0.4 -1.1 -0.9
Age started oral contraceptive pill 0.5 0.6 2.0 1.3 0.5 0.5 0.6 -0.8 0.1 1.3 0.8 -0.7 0.1 0.5 0.3 0.3 -0.1 -1.4 -0.3 -1.2 0.2 -1.1 0.2
Diastolic blood pressure, automated reading 0.2 0.7 2.6 -0.7 0.2 0.3 -1.1 1.6 0.3 0.9 -0.0 -0.0 0.2 -0.1 0.8 -0.5 1.6 1.2 0.3 0.9 -0.9 1.2 0.8
Ever depressed for a whole week 0.5 0.6 1.5 0.0 -1.0 -0.9 -1.1 0.5 -1.0 -1.0 -1.2 0.9 -1.0 -0.8 -0.9 -0.1 -0.8 -0.4 -0.7 -0.2 -0.2 -0.4 -0.5
Unable to work because of sickness or disability 0.1 0.1 1.0 0.0 -0.2 -0.4 0.0 0.3 -0.2 0.3 -0.1 -0.1 -0.2 -0.2 -0.3 0.2 0.6 -0.0 -0.1 -0.1 -1.0 0.1 -0.3
Commuting to job workplace: Cycle 0.3 0.4 2.8 0.6 0.0 -0.3 -0.3 -1.1 -0.1 1.7 0.1 0.4 -0.2 -0.0 0.0 -0.5 -0.9 -0.2 -0.4 -0.4 0.8 -0.1 0.3
Myopia 0.8 1.1 9.9 0.1 1.2 1.7 0.7 0.8 0.9 -0.1 0.5 -0.2 0.9 0.8 0.7 0.9 -0.9 0.7 0.1 1.0 3.2 0.5 0.5
Vascular/heart problems diagnosed by doctor 0.9 2.3 8.8 1.4 2.0 2.1 0.4 1.4 1.6 0.7 1.8 -1.3 1.6 1.6 1.8 1.4 0.6 1.1 0.8 1.4 3.0 1.0 1.2
Cholesterol lowering medication 0.1 0.2 1.1 -0.6 -0.3 -0.1 0.2 0.6 0.1 -1.0 -0.4 0.1 0.1 -0.1 -0.3 -0.4 0.2 0.5 0.3 0.4 -0.5 0.4 -0.1
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.6 1.5 -0.3 -1.1 -0.1 0.5 -0.5 1.6 1.3 -0.2 -0.6 -0.4 -0.4 1.2 1.0 -0.3 -0.5 -0.5 -0.7 -0.0 -0.4
Pain experienced in last month 0.6 1.1 4.4 1.3 0.3 0.2 -1.5 -1.2 -0.0 -0.7 -0.3 -0.5 0.0 0.6 -0.3 0.3 -1.4 -2.1 -0.5 -1.6 0.3 -2.1 -0.9
Supplements: Calcium 0.2 0.2 1.1 -0.7 0.1 -0.6 0.2 0.1 0.1 -0.4 -1.1 0.1 0.2 0.1 -0.3 -0.9 -0.5 -0.5 0.2 -0.3 -0.6 -0.6 -0.4
Basal cell carcinoma (self-reported) 0.3 0.4 2.3 -1.5 -0.4 -0.0 -0.2 0.5 -0.1 -0.9 -0.7 0.7 -0.1 -0.3 -0.1 -0.6 -0.0 0.8 0.1 0.9 0.5 0.7 0.6
Heart attack/myocardial infarction (self-reported) 0.5 0.7 3.3 -0.2 -1.0 -0.2 0.7 -0.8 -0.6 -0.8 0.1 -0.7 -0.6 -0.2 -0.5 0.2 0.0 -1.3 0.2 -1.4 -1.8 -1.0 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.2 -0.9 -1.0 -0.9 -0.9 0.2 -0.7 -0.3 -0.3 0.6 -0.7 -1.0 -1.0 -0.1 0.4 0.2 -0.4 -0.0 -1.1 0.2 -0.4
Heart disease (siblings) 0.2 0.2 1.6 1.3 -0.1 -0.3 -0.3 0.3 -0.2 0.8 0.2 -0.0 -0.3 -0.1 -0.1 -0.2 -0.1 -0.4 -0.4 -0.6 -0.5 -0.5 -0.1
Alcohol drinker status: Previous 0.6 0.7 4.4 1.7 0.1 0.0 -0.1 -0.8 -0.1 0.6 1.4 -0.6 -0.1 0.1 -0.4 2.1 -0.2 -0.6 -0.4 -0.8 -0.1 -0.5 -0.9
Pack years of smoking 1.5 2.2 4.2 -1.1 -1.6 -1.7 -0.7 -1.9 -1.5 -1.7 -1.8 1.5 -1.4 -1.7 -1.7 -1.0 -2.0 -1.0 -1.1 -1.0 -1.7 -1.2 -1.4
Impedance of whole body 0.8 3.8 21.4 3.7 -0.4 0.6 -0.8 -1.4 -0.9 -0.1 2.6 -1.1 -0.9 0.0 -0.5 4.6 -0.3 -2.8 -1.3 -2.6 0.5 -2.5 -2.4
Leg fat mass (left) 1.4 5.6 13.1 -0.3 -2.6 -2.8 -2.3 -1.8 -2.8 -1.2 -2.7 2.9 -2.8 -3.0 -2.5 -2.3 -2.0 -1.6 -2.4 -2.1 -3.6 -1.7 -1.8
Arm predicted mass (left) 0.3 1.4 6.7 -2.0 -0.1 0.0 0.5 0.9 0.3 -0.1 -1.3 0.9 0.3 -0.4 0.2 -2.6 0.5 2.0 0.8 1.8 -0.2 1.9 1.3