[Hub]/) : Traits : Blood Platelet Count : ← →

chr2:46,434,252-49,519,654

Best TWAS P=5.99e-19 · Best GWAS P=2.54e-12 conditioned to 0.117

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial MSH6 0.09 0.04 lasso 2 0.03 4.1e-03 5.5 5.3 1.1e-07 0.01 0.00 0.99 FALSE
2 GTEx Lung MSH6 0.16 0.02 lasso 4 0.04 2.4e-04 5.5 5.5 3.4e-08 0.03 0.00 1.00 TRUE
3 GTEx Nerve Tibial MSH6 0.13 0.03 lasso 5 0.05 1.0e-04 2.8 5.4 5.4e-08 -0.01 0.01 0.99 FALSE
4 GTEx Testis MSH6 0.26 0.19 lasso 2 0.19 1.0e-08 5.5 5.3 8.7e-08 0.01 0.00 1.00 FALSE
5 GTEx Thyroid MSH6 0.15 0.17 enet 12 0.16 3.5e-12 5.5 5.2 1.9e-07 0.00 0.00 1.00 FALSE
6 GTEx Thyroid MCFD2 0.16 0.05 enet 11 0.13 3.6e-10 -2.8 6.8 7.7e-12 0.38 0.59 0.40 FALSE
7 GTEx Thyroid AC016722.4 0.15 0.03 enet 19 0.09 3.7e-07 -6.2 8.9 6.0e-19 0.63 0.01 0.99 TRUE
8 METSIM Adipose STON1 0.06 0.00 blup 513 0.03 8.3e-06 2.8 -5.6 1.9e-08 -0.01 0.09 0.14 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma MCFD2 0.04 0.02 blup 75 0.03 3.0e-06 -5.3 6.8 9.1e-12 0.29 0.34 0.61 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MCFD2 0.02 0.01 blup 75 0.02 3.2e-03 2.3 5.9 4.3e-09 0.56 0.05 0.47 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MCFD2 0.08 0.01 lasso 5 0.05 1.7e-06 6.4 8.2 2.9e-16 0.63 0.01 0.99 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma MCFD2 0.14 0.07 enet 17 0.07 8.5e-04 -6.2 5.4 5.3e-08 0.03 0.06 0.27 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma MCFD2 0.13 0.09 blup 75 0.11 7.6e-12 -2.8 5.4 5.7e-08 0.22 0.93 0.06 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma MCFD2 0.08 0.04 enet 9 0.05 9.1e-06 -2.8 6.5 6.7e-11 0.38 0.42 0.49 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma MSH6 0.11 0.06 enet 6 0.12 5.3e-12 5.5 5.2 1.5e-07 0.00 0.00 1.00 FALSE