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chr2:46,434,252-49,519,654

Best TWAS P=5.99e-19 · Best GWAS P=2.54e-12 conditioned to 0.117

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Thyroid	AC016722.4	0.15	0.03	enet	19	0.09	3.7e-07	-6.2	8.9	6.0e-19	0.63	0.01	0.99	TRUE
8	METSIM	Adipose	STON1	0.06	0.00	blup	513	0.03	8.3e-06	2.8	-5.6	1.9e-08	-0.01	0.09	0.14	TRUE
2	GTEx	Lung	MSH6	0.16	0.02	lasso	4	0.04	2.4e-04	5.5	5.5	3.4e-08	0.03	0.00	1.00	TRUE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MCFD2	0.08	0.01	lasso	5	0.05	1.7e-06	6.4	8.2	2.9e-16	0.63	0.01	0.99	FALSE
6	GTEx	Thyroid	MCFD2	0.16	0.05	enet	11	0.13	3.6e-10	-2.8	6.8	7.7e-12	0.38	0.59	0.40	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	MCFD2	0.04	0.02	blup	75	0.03	3.0e-06	-5.3	6.8	9.1e-12	0.29	0.34	0.61	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	MCFD2	0.08	0.04	enet	9	0.05	9.1e-06	-2.8	6.5	6.7e-11	0.38	0.42	0.49	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MCFD2	0.02	0.01	blup	75	0.02	3.2e-03	2.3	5.9	4.3e-09	0.56	0.05	0.47	FALSE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	MCFD2	0.14	0.07	enet	17	0.07	8.5e-04	-6.2	5.4	5.3e-08	0.03	0.06	0.27	FALSE
3	GTEx	Nerve Tibial	MSH6	0.13	0.03	lasso	5	0.05	1.0e-04	2.8	5.4	5.4e-08	-0.01	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	MCFD2	0.13	0.09	blup	75	0.11	7.6e-12	-2.8	5.4	5.7e-08	0.22	0.93	0.06	FALSE
4	GTEx	Testis	MSH6	0.26	0.19	lasso	2	0.19	1.0e-08	5.5	5.3	8.7e-08	0.01	0.00	1.00	FALSE
1	GTEx	Artery Tibial	MSH6	0.09	0.04	lasso	2	0.03	4.1e-03	5.5	5.3	1.1e-07	0.01	0.00	0.99	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	MSH6	0.11	0.06	enet	6	0.12	5.3e-12	5.5	5.2	1.5e-07	0.00	0.00	1.00	FALSE
5	GTEx	Thyroid	MSH6	0.15	0.17	enet	12	0.16	3.5e-12	5.5	5.2	1.9e-07	0.00	0.00	1.00	FALSE