TWAS hub - CCDC102A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1640	0.0380	1.7e-07	0.092	0.065	0.110	0.093	0.102	3.0e-11	2.5e-08	2.9e-13	2.2e-11	2.3e-12
2	GTEx	Cells Transformed fibroblasts	0.1690	0.0450	1.1e-04	0.064	NA	0.051	NA	0.069	1.4e-05	NA	1.0e-04	NA	7.5e-06
3	GTEx	Heart Left Ventricle	0.1879	0.0594	1.6e-03	0.048	NA	0.131	NA	0.080	1.5e-03	NA	1.9e-07	NA	5.0e-05
4	GTEx	Muscle Skeletal	0.0963	0.0343	3.4e-03	0.077	NA	0.064	NA	0.062	5.1e-08	NA	7.0e-07	NA	1.0e-06
5	GTEx	Skin Sun Exposed Lower leg	0.1680	0.0500	2.8e-04	0.076	NA	0.038	NA	0.073	7.6e-07	NA	3.9e-04	NA	1.1e-06
6	GTEx	Uterus	0.4540	0.1280	3.0e-03	-0.015	NA	0.033	NA	-0.012	9.0e-01	NA	7.2e-02	NA	6.7e-01
7	METSIM	Adipose	0.1190	0.0332	8.8e-06	0.060	0.044	0.041	0.052	0.056	2.3e-09	2.8e-07	6.8e-07	2.8e-08	7.8e-09
8	YFS	Blood	0.0816	0.0179	4.1e-11	0.038	0.050	0.058	0.057	0.058	1.4e-12	7.2e-16	3.3e-18	4.3e-18	2.1e-18
9	TCGA	Breast Invasive Carcinoma	0.0193	0.0093	2.7e-04	0.010	0.015	0.015	NA	0.016	2.9e-03	3.8e-04	3.6e-04	NA	2.1e-04
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0790	0.0440	5.4e-03	0.014	0.048	0.050	NA	0.031	4.9e-02	9.2e-04	8.0e-04	NA	6.7e-03
11	TCGA	Brain Lower Grade Glioma	0.0546	0.0228	6.8e-06	0.054	0.049	0.038	NA	0.049	8.1e-07	3.0e-06	3.2e-05	NA	2.5e-06
12	TCGA	Prostate Adenocarcinoma	0.0469	0.0198	1.5e-05	0.058	0.054	0.048	NA	0.048	9.7e-07	2.2e-06	8.2e-06	NA	8.3e-06
13	TCGA	Thyroid Carcinoma	0.1220	0.0440	5.1e-10	0.038	0.101	0.101	NA	0.100	1.3e-04	5.0e-10	4.8e-10	NA	6.3e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Crohns Disease (2012)	4.4	7.2	11.0	-3.3	-3.0	-2.6	-3.3	-2.1	-1.2	-2.9	-1.3	-3.2	-2.1	-3.3	-3.1	-2.1
Medication: Levothyroxine sodium	4.4	7.4	14.3	-3.5	-2.4	-1.5	-3.8	-3.6	-0.8	-2.8	-3.1	-2.5	-1.9	-3.0	-2.6	-2.3
Tinnitus: Yes, now most or all of the time	4.3	5.0	11.8	-2.4	-2.0	-3.4	-1.9	-1.6	0.9	-2.6	-1.0	-2.5	-1.4	-2.5	-2.4	-2.9
Hypothyroidism/myxoedema (self-reported)	4.0	7.8	13.6	-3.5	-2.6	-1.2	-3.7	-3.6	-1.5	-2.8	-3.0	-2.5	-1.9	-3.2	-2.5	-3.0
Hypothyroidism (self reported)	3.7	8.5	15.5	-3.9	-2.7	-2.0	-3.7	-3.9	-1.2	-2.8	-2.6	-2.4	-2.4	-3.5	-2.4	-3.2
Pulse wave peak to peak time	3.4	4.0	7.9	1.9	2.3	1.6	2.1	1.7	0.2	2.8	1.5	2.7	1.6	2.2	2.3	1.7
Pulse wave Arterial Stiffness index	3.3	3.8	7.6	-1.9	-2.2	-1.6	-2.0	-1.8	-0.1	-2.8	-1.5	-2.7	-1.5	-2.1	-2.2	-1.7
Commuting to job workplace: Car/motor vehicle	3.0	3.4	8.1	1.4	1.5	1.9	1.6	2.1	1.3	1.3	2.8	1.6	0.8	1.9	2.2	2.5
Reason for reducing amount of alcohol drunk: Health precaution	2.8	3.3	10.5	0.5	0.9	0.9	0.9	2.9	2.2	2.1	3.2	1.1	0.1	1.1	1.5	2.6
Crohns Disease (2017)	2.7	6.0	12.2	-3.5	-2.6	-2.5	-2.5	-1.7	-1.1	-2.3	-0.6	-2.8	-3.0	-2.9	-2.5	-2.2
Medication: Ramipril	2.6	3.3	5.0	2.0	1.8	1.8	1.7	1.8	1.4	2.0	1.8	2.2	1.7	1.8	2.1	1.6
Medication for hormone replacement therapy	2.5	2.8	4.5	1.5	1.7	-0.4	1.8	2.0	2.1	1.3	2.1	1.2	1.8	1.8	2.1	1.1
Glaucoma (self-reported)	2.5	2.9	4.4	-1.0	-2.0	-0.6	-2.0	-1.5	-2.1	-1.2	-1.6	-1.7	-2.0	-1.9	-1.7	-2.1
Medication for cholesterol	2.5	3.8	7.7	-1.8	-1.7	-1.6	-2.2	-2.5	-1.2	-2.6	-2.8	-1.9	-0.6	-2.1	-2.0	-1.2
Ever taken oral contraceptive pill	2.5	2.8	6.0	-1.1	-2.1	-1.6	-1.6	-1.2	-0.7	-1.1	-1.2	-1.7	-1.6	-1.9	-2.4	-2.5
Mother’s age at death	2.5	3.2	5.3	1.5	2.2	0.8	2.3	1.5	0.2	2.0	1.5	1.9	2.1	2.0	2.1	1.7
Medication: Bendroflumethiazide	2.5	3.8	8.4	2.0	1.7	2.9	2.0	2.0	0.9	2.3	2.0	1.9	0.6	2.1	1.4	2.2
Alzheimer’s Disease (in father)	2.4	2.6	5.9	1.0	2.1	0.6	1.8	2.1	0.2	1.6	1.4	2.1	0.9	2.0	2.4	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	6.8	1.0	1.8	1.2	1.5	1.3	0.3	2.1	1.6	2.6	1.8	1.6	2.3	1.5
Asthma	2.2	4.3	10.8	3.3	2.1	2.0	2.1	2.1	-0.2	2.5	1.5	2.3	1.2	2.3	2.3	1.4
Relative age of first facial hair	2.1	4.3	9.5	2.1	1.8	2.1	2.2	3.1	2.8	1.9	1.7	1.7	1.0	2.1	1.9	1.6
Time employed in main current job	2.1	2.4	4.9	-0.6	-1.2	-1.9	-1.8	-1.8	-1.3	-1.2	-1.9	-1.3	-1.5	-1.4	-2.2	-1.2
Mouth/teeth dental problems: Dentures	2.1	3.6	7.5	2.7	1.9	1.4	2.2	2.3	1.2	1.6	1.6	1.6	2.0	2.1	1.3	2.0
Loud music exposure frequency	2.1	2.2	4.7	-1.9	-1.3	-1.1	-1.3	-1.1	-2.2	-1.3	-1.1	-1.1	-1.8	-1.6	-1.6	-1.7
Medication: Paracetamol	2.1	3.4	5.9	1.7	2.2	0.4	2.0	1.9	2.4	1.7	1.7	2.1	1.2	1.8	1.9	2.0
Eye problems/disorders: Cataract	2.1	2.4	5.1	-0.9	-1.6	-0.6	-1.5	-1.7	-0.3	-1.8	-1.8	-2.1	-0.6	-1.3	-2.1	-2.3
Asthma (self-reported)	2.1	4.2	10.0	3.2	2.0	1.9	2.0	2.2	-0.3	2.5	1.6	2.2	1.0	2.2	2.2	1.6
Pulse rate	2.0	3.4	5.9	-0.8	-2.3	-1.7	-2.4	-1.5	-1.5	-1.8	-2.1	-2.4	-1.2	-2.0	-2.4	-0.9
Blood Platelet Count	1.9	21.9	42.6	6.5	5.0	2.6	5.5	4.6	3.0	4.0	3.9	4.1	4.8	5.8	4.8	4.6
Medication: Atenolol	1.9	2.4	5.0	-1.3	-1.2	-0.9	-1.6	-1.2	0.5	-1.9	-1.5	-1.4	-2.2	-1.5	-2.2	-1.7
Alcohol intake versus 10 years previously	1.9	2.8	4.8	-2.1	-1.4	-2.1	-1.9	-1.7	0.5	-1.6	-1.6	-1.2	-1.4	-2.2	-2.1	-1.3
Illnesses of siblings: Diabetes	1.9	2.3	4.7	-0.6	-1.4	-1.5	-1.4	-1.6	-0.0	-2.2	-1.7	-1.8	-0.1	-1.4	-2.1	-1.9
Eye problems/disorders: Glaucoma	1.9	2.3	5.0	-0.5	-1.8	-0.4	-1.5	-1.2	-2.2	-1.2	-1.2	-1.7	-2.1	-1.5	-1.2	-1.8
Fractured/broken bones in last 5 years	1.8	2.3	5.6	1.0	1.2	0.6	1.7	1.5	-0.0	2.4	2.2	2.1	1.0	1.4	1.3	1.6
Depression (Nagel 2018)	1.7	2.6	4.5	-2.0	-2.0	-1.2	-1.6	-1.1	-1.7	-1.4	-0.9	-1.6	-2.1	-2.0	-1.5	-1.0
Blood Red Count	1.7	16.8	32.3	5.7	4.7	2.7	5.2	4.5	1.9	3.4	3.0	3.5	3.9	5.2	4.7	3.0
Major Depression (MDD)	1.6	1.9	4.4	-1.4	-2.1	-0.8	-2.0	-1.2	-0.5	-1.2	-1.0	-1.0	-1.3	-1.9	-1.7	-1.0
Lupus	1.6	2.5	5.7	-1.4	-1.6	-1.0	-1.7	-2.4	-0.1	-1.5	-2.2	-1.3	-1.1	-1.6	-2.1	-0.9
Medication: Paracetamol	1.6	2.4	3.9	1.4	1.9	0.4	1.6	1.8	2.0	1.3	1.5	1.8	1.3	1.4	1.8	1.6
Ever depressed for a whole week	1.6	2.0	6.8	1.1	1.3	0.0	1.5	1.8	2.6	1.2	1.9	0.8	0.3	1.2	1.0	1.6
Hayfever, allergic rhinitis or eczema	1.5	3.2	8.0	1.5	1.8	0.3	2.3	2.0	0.9	2.8	1.8	2.4	0.2	2.0	1.8	1.0
Peak expiratory flow (PEF)	1.5	3.4	9.6	-3.1	-1.6	-2.5	-1.9	-2.6	-1.6	-0.8	-1.7	-0.8	-1.1	-1.9	-1.2	-1.8
Number of children fathered	1.5	1.7	3.4	1.2	1.8	0.5	1.6	0.9	-0.0	1.3	0.2	1.5	1.3	1.8	1.4	1.5
Age at last live birth	1.5	2.2	4.1	1.6	1.1	1.5	1.8	1.9	0.1	1.3	2.0	0.8	0.5	1.9	1.9	1.1
Maternal smoking around birth	1.4	2.0	4.8	-2.2	-1.4	-1.1	-1.8	-0.8	-0.8	-1.3	-0.5	-1.7	-1.5	-1.7	-1.2	-1.5
Qualifications: CSEs or equivalent	1.4	1.9	4.2	-0.9	-1.3	-1.7	-1.3	-1.3	2.1	0.0	-1.3	-0.3	-1.8	-1.5	-1.9	-0.9
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	3.6	1.9	1.0	0.1	1.3	0.3	0.5	1.6	0.9	1.7	0.8	1.5	1.5	1.7
Medication for pain relief, constipation, heartburn	1.4	2.4	5.4	-1.2	-1.7	-0.3	-1.8	-2.3	-2.0	-1.5	-2.1	-1.3	0.2	-1.4	-0.8	-1.6
Number of full sisters	1.4	1.7	3.4	1.1	1.5	0.9	1.6	1.4	0.6	1.7	0.8	1.8	0.6	1.4	1.2	1.5
Unable to work because of sickness or disability	1.4	1.9	5.0	-1.5	-0.7	-1.0	-1.3	-1.4	-1.6	-1.5	-2.2	-1.0	-1.3	-1.2	-1.6	-0.5
Blood White Count	1.3	9.5	14.1	3.8	3.1	2.7	3.6	2.3	2.5	2.4	2.9	2.9	3.2	3.7	3.6	3.0
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.1	8.0	-1.7	-1.2	-2.8	-1.0	-1.6	-0.1	-1.1	-0.7	-1.4	-0.5	-1.6	-1.7	-1.3
Allergy	1.3	3.1	6.2	-2.1	-1.9	-0.7	-2.1	-2.0	-0.3	-2.5	-1.5	-2.3	-0.5	-1.9	-1.8	-1.2
Hair/balding pattern: Pattern 3	1.3	2.0	5.8	-0.1	-1.6	-0.5	-1.2	-1.4	0.1	-1.3	-1.8	-1.6	-1.2	-1.0	-2.0	-2.4
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	4.5	-1.4	-2.1	-1.2	-2.1	-1.9	-0.9	-1.4	-0.6	-1.5	0.0	-1.8	-1.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	5.4	-2.0	-2.3	-1.9	-1.9	-1.6	-1.9	-1.0	-0.8	-1.1	-0.7	-2.0	-1.2	-1.9
Miserableness	1.3	2.2	3.2	-1.1	-1.3	-1.7	-1.6	-1.3	-1.2	-1.8	-1.6	-1.8	-0.8	-1.6	-1.7	-1.5
Medication: Blood pressure	1.3	2.5	8.7	1.1	1.3	3.0	1.6	2.2	0.6	1.6	1.9	1.3	-0.3	1.6	0.9	1.4
Average weekly beer plus cider intake	1.3	1.8	4.1	1.0	1.8	-0.4	1.3	0.9	1.4	1.2	0.3	1.8	2.0	1.5	1.7	1.1
Ever had prostate specific antigen (PSA) test	1.3	1.4	3.6	0.1	0.9	0.6	1.2	1.8	1.1	1.0	1.9	0.7	0.3	1.2	1.4	1.8
Blood Eosinophil Count	1.2	9.1	16.9	4.1	3.1	2.0	3.2	2.6	3.8	1.7	3.7	1.5	3.4	3.2	3.5	1.8
Average weekly spirits intake	1.2	1.5	4.1	-0.1	-1.5	-0.7	-1.5	-0.0	0.3	-1.2	-1.1	-1.7	-2.0	-1.2	-1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	4.2	1.5	1.2	-0.6	0.9	1.3	0.8	2.0	0.9	2.1	0.8	0.9	1.7	0.5
Chest pain or discomfort	1.2	1.7	4.1	1.7	1.8	0.5	1.5	0.9	1.8	0.7	0.7	1.0	1.1	1.3	0.8	2.0
Average weekly champagne plus white wine intake	1.2	1.7	3.0	-1.3	-1.5	-0.6	-1.5	-0.7	-0.8	-1.7	-1.6	-1.4	-1.0	-1.3	-1.1	-1.6
Number of operations (self-reported)	1.2	1.8	3.1	1.4	1.6	1.4	1.6	0.7	1.4	0.6	1.3	0.7	1.7	1.8	1.4	1.2
Respiratory disease	1.1	2.4	6.5	2.6	1.3	2.5	1.7	2.1	-0.3	1.4	1.2	1.0	-0.1	1.6	1.4	0.8
Alcohol usually taken with meals	1.1	1.7	5.1	-1.0	-1.7	0.3	-0.9	-0.8	-2.2	-1.5	-1.1	-1.5	-0.6	-0.9	-0.7	-2.2
Chronic bronchitis/emphysema (mother)	1.1	1.3	3.5	-1.9	-1.0	0.4	-1.8	-0.3	-1.8	-0.5	-0.6	-0.3	-1.4	-1.5	-0.7	0.4
Exposure to tobacco smoke outside home	1.1	1.4	3.7	0.6	0.9	1.9	1.2	1.9	-0.0	1.0	1.7	0.6	0.3	1.1	1.2	1.4
Leg pain on walking	1.1	1.3	6.2	-1.6	-0.5	-2.5	-0.8	-0.4	1.9	-0.7	0.1	-0.7	-1.1	-1.1	-0.7	-0.2
Average weekly red wine intake	1.1	1.6	5.8	-1.2	-0.9	-2.4	-0.7	-0.6	1.1	-1.3	-0.0	-1.3	-1.6	-1.0	-1.0	-1.8
Loneliness, isolation	1.1	1.6	4.1	-1.2	-0.8	-1.8	-1.2	-1.0	0.6	-2.0	-1.1	-1.6	-0.3	-1.5	-1.2	-0.8
Mineral and other dietary supplements	1.1	1.5	3.6	-0.9	-0.6	-1.4	-0.7	-0.3	-1.5	-0.8	-1.9	-1.1	-0.3	-1.2	-1.6	-1.8
Smoking status: Current	1.1	1.7	4.9	-2.2	-1.4	-0.7	-1.3	-0.4	-1.2	-1.4	-1.0	-1.3	-1.7	-1.4	-1.1	-0.7
Intelligence (Savage-Jansen 2018)	1.0	2.9	7.0	2.3	2.6	0.1	2.5	1.1	1.0	1.3	0.5	1.7	2.1	2.2	1.7	0.6
Schizophrenia vs Biploar Disorder	1.0	1.3	4.7	1.1	0.6	2.2	1.0	0.9	1.6	1.0	0.5	1.1	0.1	1.0	1.0	1.2
Fasting Glucose	1.0	1.2	2.4	-1.0	-1.4	-1.2	-1.6	-1.5	0.5	-0.4	-1.4	0.2	-0.8	-1.1	-1.4	-0.3
Chronotype (morning person)	1.0	2.3	7.7	-1.6	-1.5	-1.0	-0.8	-0.2	-2.8	-0.4	-0.8	-1.2	-2.8	-1.1	-1.5	-1.5
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.6	0.6	-0.6	-0.5	-0.1	1.0	1.9	0.7	2.4	0.3	0.2	-0.1	0.7	1.6
Townsend deprivation index at recruitment	1.0	1.5	3.0	-0.6	-0.7	-0.8	-1.0	-0.5	-1.6	-1.7	-1.7	-1.7	-0.9	-0.9	-1.6	-0.9
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	5.1	0.7	0.9	-0.2	1.2	0.9	0.8	1.0	0.1	1.4	2.3	1.3	1.0	0.1
Medication: Omeprazole	1.0	1.2	6.4	0.1	0.6	-2.5	0.2	0.9	2.3	-1.2	0.5	-1.1	-0.5	-0.3	-0.1	0.1
Myopia	1.0	1.4	4.8	-1.6	-0.6	-1.9	-0.1	-0.6	-1.0	0.0	-1.3	-0.5	-1.5	-0.5	-1.2	-2.2
Irritable Bowel Disease (IBD)	0.9	2.1	4.8	-1.6	-1.7	-2.2	-1.5	-1.0	-0.1	-1.3	-0.5	-1.6	-1.4	-1.8	-1.7	-1.1
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.6	-1.1	-1.0	-0.8	-0.8	-1.0	-0.6	-0.8	-0.8	-1.3	-0.4	-1.1	-1.6	-1.0
Allergy or Eczema	0.9	2.4	5.4	1.3	1.4	0.1	2.0	2.1	0.9	2.3	1.7	1.8	-0.6	1.6	1.5	1.1
Frequency of depressed mood in last 2 weeks	0.9	1.3	3.1	-1.6	-1.0	-1.8	-0.7	-0.5	-0.8	-1.2	-0.9	-1.1	-1.1	-1.1	-1.4	-0.9
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	2.8	-0.9	-0.5	-0.3	-1.1	-0.7	-1.1	-1.7	-1.0	-1.5	-0.7	-1.2	-1.6	-0.6
Severe depression (siblings)	0.9	1.0	2.7	-1.1	-0.8	-1.6	-0.9	-0.8	0.8	-0.6	0.6	-1.2	-1.4	-1.1	-1.2	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	4.1	-1.2	-1.1	-2.0	-1.0	-0.3	0.3	-1.3	0.1	-1.6	-1.2	-1.4	-1.7	-1.1
High blood pressure (siblings)	0.9	1.3	3.5	-0.8	-1.1	-0.9	-1.2	-1.4	-0.2	-1.3	-1.3	-1.0	0.4	-0.9	-1.9	-1.1
Comparative height size at age 10	0.9	4.9	9.2	1.4	3.0	1.8	2.3	1.6	1.0	2.8	1.6	2.9	2.1	2.5	2.5	2.4
Family relationship satisfaction	0.9	1.1	2.3	-1.3	-1.5	-0.9	-1.3	-0.2	-0.7	-1.0	-0.0	-1.3	-1.1	-1.4	-0.8	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.0	0.5	1.2	0.1	1.1	1.7	-0.1	1.0	1.1	1.0	-0.7	1.1	1.1	1.0
Handedness (chirality/laterality): Left-handed	0.9	1.1	4.5	1.4	1.0	-1.1	0.8	1.1	2.1	0.4	0.9	0.3	0.6	0.9	1.0	0.6
Verbal and Numeric Reasoning (VNR)	0.8	2.0	4.9	2.2	2.0	-0.5	1.9	0.3	1.0	1.1	0.3	1.5	1.8	1.9	1.4	0.2
Prostate Cancer	0.8	1.2	3.4	0.6	0.9	-0.0	1.0	1.2	-1.9	1.1	1.4	1.0	0.7	0.9	1.4	0.8
Relative age voice broke	0.8	1.3	2.6	1.0	0.9	1.6	1.1	1.4	1.6	1.2	0.9	1.0	-0.2	1.3	1.2	0.1
Impedance of arm (right)	0.8	3.8	6.6	2.6	1.7	0.9	1.8	1.8	1.4	2.4	2.0	2.0	2.0	1.7	2.2	2.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	3.9	-1.0	0.5	-2.0	0.2	-1.0	-1.8	0.1	-1.0	0.4	-1.2	0.1	-0.5	-0.3
Medication: Blood pressure	0.8	1.5	6.7	1.5	1.2	0.2	1.3	0.9	2.6	0.7	1.0	0.7	1.4	1.1	0.5	1.0
Hypertension (Self-reported)	0.8	2.2	5.6	1.3	2.0	0.8	1.9	1.6	2.4	1.2	1.4	1.1	1.3	1.6	0.9	1.0
Back pain experienced in last month	0.8	1.2	3.8	-0.7	-0.1	-1.4	-0.8	-1.8	0.7	-1.4	-2.0	-0.9	0.6	-0.7	-1.0	-0.5
Supplements: Fish oil (including cod liver oil)	0.8	1.0	4.4	0.1	0.2	1.7	-0.0	-0.1	0.8	0.5	1.6	0.7	0.1	0.7	0.9	2.1
Alcohol drinker status: Never	0.8	0.9	2.7	0.9	1.1	-0.2	1.1	0.5	1.6	0.7	0.5	0.9	0.9	0.8	1.3	1.1
Reaction Time	0.7	1.3	4.0	-0.5	-1.0	-0.1	-1.4	-1.3	-0.4	-2.0	-1.7	-1.7	-0.2	-0.7	-1.2	-0.3
HDL Cholesterol	0.7	1.1	5.3	0.7	0.7	0.3	0.8	1.5	2.3	0.9	0.6	0.8	-0.7	0.7	0.8	1.2
LDL Cholesterol	0.7	1.2	2.2	-1.3	-1.3	-0.7	-1.5	-0.1	-0.6	-1.1	-0.3	-1.4	-1.0	-1.5	-1.1	-0.9
Lung FEV1/FVC ratio	0.7	3.3	14.8	-3.5	-0.2	-3.0	-1.0	-1.4	-3.8	-0.9	-0.4	-0.1	-0.7	-1.1	-1.0	-0.8
Lung FVC	0.7	3.6	5.9	-2.4	-2.3	-1.7	-2.1	-1.9	-0.0	-1.9	-1.4	-2.1	-1.7	-2.3	-1.4	-2.1
Current tobacco smoking	0.7	1.2	3.1	-1.8	-1.2	-0.7	-1.1	-0.2	-1.1	-1.1	-0.9	-1.1	-1.6	-1.2	-1.0	-0.7
High blood pressure	0.7	1.9	4.9	1.1	1.9	0.6	1.7	1.3	2.2	1.2	1.3	1.0	1.2	1.5	0.7	1.0
Number of incorrect matches in round	0.7	1.2	4.1	-2.0	-1.4	-1.0	-1.5	-1.3	0.5	-0.6	-0.7	-0.4	-0.4	-1.4	-0.8	-0.0
Illnesses of siblings	0.7	1.0	3.5	0.6	0.5	1.2	1.1	1.5	-0.0	1.0	1.1	0.7	-0.3	0.7	1.9	0.7
Father’s age at death	0.7	0.9	8.9	-0.2	-0.5	0.4	-0.1	0.1	-3.0	-0.3	-1.1	-0.3	-0.6	-0.1	-0.3	-0.6
Medication: Cholesterol lowering	0.7	1.0	4.1	0.1	-1.3	-0.8	-0.7	-0.5	1.0	-1.0	-0.5	-1.4	-0.6	-0.6	-2.0	-1.0
Depression (self-reported)	0.7	0.9	2.9	-1.7	-0.5	-1.7	-0.9	-0.5	-0.3	-1.0	-1.0	-0.2	1.1	-1.1	-0.3	-0.0
Illnesses of father: Heart disease	0.7	1.0	1.9	-1.2	-1.2	-1.3	-0.7	-0.2	0.1	-0.7	0.9	-1.0	-0.5	-1.3	-1.1	-1.4
Mood swings	0.7	1.3	7.3	-1.1	-0.3	-2.7	-0.5	-0.1	1.8	-1.1	-0.1	-0.8	-0.4	-1.0	-0.7	-1.0
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.3	-0.4	-1.1	-0.5	-1.2	-0.4	-0.8	-1.3	0.4	-1.8	-0.2	-1.2	-0.9	-0.1
Risk taking	0.7	1.0	6.0	-1.4	-0.5	-2.5	-0.5	0.2	-0.4	-1.2	-0.2	-1.0	-0.9	-0.9	-0.7	-0.4
Vascular/heart problems diagnosed by doctor	0.7	1.8	6.6	-1.3	-1.7	-0.6	-1.4	-1.2	-2.6	-1.0	-1.3	-0.7	-1.3	-1.3	-0.3	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	4.2	0.2	0.5	-2.0	0.0	1.1	1.2	-0.7	1.1	-0.7	-0.9	-0.4	-0.0	0.3
Basal cell carcinoma (self-reported)	0.7	0.8	2.2	0.4	1.4	0.2	0.9	-0.2	-0.9	0.6	-0.1	1.0	1.3	1.5	0.6	0.7
Pack years of smoking	0.7	1.0	2.5	-0.5	-0.9	-0.6	-0.3	0.0	-1.6	-1.0	-0.4	-1.6	-1.2	-0.8	-1.2	-1.5
Age at First Birth	0.6	0.8	3.6	0.9	0.7	0.0	0.1	0.7	1.9	0.4	0.4	0.9	-0.4	0.6	0.9	1.6
Primary Biliary Cirrhosis	0.6	0.9	2.7	1.0	1.1	-0.5	0.8	1.6	0.7	1.1	1.1	0.6	0.5	0.9	0.7	0.8
Rheumatoid Arthritis	0.6	0.8	3.3	-1.1	-1.3	-1.4	-0.5	-0.0	-1.0	-0.2	0.6	-0.6	-1.8	-0.8	-0.4	-0.2
Medication: Metformin	0.6	0.8	2.7	0.4	-0.2	-1.0	-0.5	-0.8	0.8	-1.6	-0.5	-1.3	1.2	-0.4	-1.0	-0.3
Diabetes (father)	0.6	0.7	2.5	-1.6	-0.9	-0.4	-1.0	-1.4	0.2	-0.5	-0.8	-0.3	-1.0	-0.6	-0.4	-0.7
Pack years adult smoking proportion	0.6	0.9	2.1	-0.5	-0.8	-0.5	-0.2	-0.0	-1.4	-0.9	-0.6	-1.3	-1.1	-0.7	-1.2	-1.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	3.8	0.2	0.2	-0.3	0.3	1.1	2.0	0.6	1.2	0.1	-0.1	0.4	0.3	1.2
Impedance of arm (left)	0.6	2.6	4.5	2.1	1.4	0.8	1.4	1.4	0.9	1.9	1.7	1.6	1.9	1.4	1.8	1.8
Pulse wave reflection index	0.6	0.7	2.4	-1.6	-0.9	-0.8	-0.3	0.1	-0.3	-0.9	-0.0	-0.9	-1.4	-1.0	-0.6	-0.7
Medication: Allopurinol	0.6	0.7	2.0	0.3	-1.0	-0.1	-1.0	-1.3	-0.3	-1.4	-0.9	-0.9	0.5	-0.7	-0.9	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.5	0.1	-0.9	-0.9	-1.0	-0.7	-0.4	-0.7	-0.8	-0.7	-1.2	-0.9	-0.8	-0.9
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.3	1.0	0.6	1.1	0.2	-0.2	0.5	0.5	1.4	0.4	0.5	0.5	0.7	1.8
Ever had bowel cancer screening	0.6	0.7	3.9	-0.4	-0.1	0.2	0.4	0.8	-0.7	1.4	0.6	0.8	-2.0	0.3	0.3	-0.2
Medication: Aspirin	0.6	0.8	2.6	-0.3	-0.5	-0.2	-1.0	-0.3	1.6	-1.0	0.0	-1.2	-1.0	-1.1	-1.4	-0.4
Body Mass Index (BMI) (2010)	0.5	0.6	1.7	-1.2	-0.6	-0.4	-0.8	-0.4	-0.6	-0.1	-0.9	-0.5	0.0	-0.9	-1.1	-1.3
Coronary Artery Disease (CAD)	0.5	0.5	1.5	-1.2	-0.8	-0.1	-0.8	-0.9	-1.2	-0.5	0.1	-0.3	-0.6	-0.9	-0.6	0.5
Ever had hysterectomy (womb removed)	0.5	0.6	1.4	-0.4	0.4	1.1	0.6	0.4	0.4	0.6	1.0	0.9	-0.9	0.6	0.9	1.2
Vitamin and mineral supplements	0.5	0.7	4.1	-0.0	0.8	1.0	0.6	0.4	-2.0	-0.1	-0.3	0.0	1.4	0.5	0.3	0.3
Supplements: Zinc	0.5	0.5	1.6	0.9	0.4	1.3	0.8	0.6	0.1	0.9	0.1	0.5	0.2	1.0	0.8	0.2
Medication: Co-codamol	0.5	0.5	1.2	1.0	0.6	1.0	0.6	1.1	-0.5	0.6	0.3	0.5	0.4	0.9	-0.0	1.0
Multivitamins +/- minerals	0.5	0.6	4.4	0.3	-0.2	-0.7	-0.4	-0.7	2.1	-0.2	-0.4	-0.1	-1.2	-0.1	-0.4	-0.6
Sitting height	0.5	3.6	6.0	0.6	2.4	0.9	2.3	2.2	1.5	2.1	2.0	2.0	1.6	1.9	2.3	1.7
Had menopause	0.5	0.6	3.0	-0.4	0.9	-0.0	0.4	1.5	-0.2	0.5	1.7	0.6	0.3	0.2	0.7	0.8
Heart attack	0.5	0.6	2.2	-0.4	-0.8	0.1	-0.6	-0.6	-0.0	-0.8	-0.6	-0.9	-0.9	-0.7	-1.5	-1.0
Worrier / anxious feelings	0.5	1.0	2.1	-0.5	-1.2	-0.9	-1.4	-1.1	0.3	-1.2	-1.1	-0.8	1.0	-1.0	-1.2	-0.4
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	6.9	-2.6	-1.0	-2.0	-1.2	-1.9	-0.1	-0.9	-1.0	-0.6	-0.8	-1.5	-0.5	-1.4
Happiness	0.5	0.6	2.6	-0.4	-0.9	-1.6	-0.4	0.7	-0.8	-0.1	0.9	-0.4	-0.7	-1.0	-0.4	-0.7
Lung cancer (father)	0.5	0.5	1.6	1.3	0.7	0.6	0.7	0.9	0.8	0.6	0.6	0.5	-0.6	0.6	0.5	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	5.4	-2.3	-1.1	-1.6	-1.2	-1.7	-0.6	-0.9	-0.9	-0.7	-0.7	-1.4	-0.6	-1.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	5.8	0.6	0.3	-2.4	-0.1	-0.1	0.8	-0.1	-0.3	-0.3	0.3	-0.1	-0.3	-0.6
Age at first live birth	0.5	0.8	2.9	0.9	0.5	1.7	0.9	0.9	0.1	0.9	0.8	0.6	0.7	1.1	1.1	0.5
Health satisfaction	0.5	0.7	2.0	-0.2	-0.6	-1.1	-0.8	0.1	0.8	-0.7	-0.1	-1.0	-1.4	-0.7	-1.1	-1.0
Shortness of breath walking on level ground	0.5	0.6	1.6	-0.4	-0.7	-1.2	-1.0	-0.0	0.3	-1.3	0.5	-1.2	-0.4	-0.9	-0.8	0.4
Emphysema/chronic bronchitis	0.5	0.6	1.8	0.4	1.1	1.3	0.6	-0.2	-1.0	-0.2	-0.5	-0.2	1.1	0.5	-0.3	1.3
Migraine (self-reported)	0.5	0.7	1.8	-1.0	-0.6	-1.1	-0.8	0.2	-0.2	-0.3	-0.6	-0.3	-1.1	-0.7	-1.3	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.7	0.5	0.5	-0.1	0.6	0.8	1.2	1.3	0.4	0.9	-1.0	0.7	0.3	0.5
Medication: Aspirin	0.5	0.6	2.8	0.2	-0.2	-0.2	-0.6	0.1	1.7	-0.5	0.1	-0.9	-1.1	-0.7	-1.4	-0.2
Long-standing illness, disability or infirmity	0.5	0.8	2.8	-0.2	-0.4	-0.4	-0.5	-0.8	0.7	-1.2	-0.9	-1.4	-0.1	-0.9	-1.7	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.9	-0.5	-0.5	0.0	-0.3	-0.6	-1.4	-1.3	-0.3	-1.1	0.1	-0.0	-0.3	-1.0
Qualifications: nursing, teaching	0.5	0.8	3.4	-0.9	-0.4	-0.4	-0.5	-0.8	-0.8	-1.0	-1.5	-0.8	0.6	-0.5	-0.6	-1.8
Osteoarthritis (self-reported)	0.5	0.6	1.4	-0.4	-0.7	1.1	-0.6	-0.7	-1.1	-1.1	-0.9	-0.8	-0.1	-0.3	-1.2	-0.1
Medication: Gliclazide	0.5	0.6	1.8	0.2	-0.8	0.1	-0.6	-0.4	-1.0	-0.9	-0.4	-1.1	-0.3	-0.5	-1.0	-1.3
Financial situation satisfaction	0.5	0.6	3.9	-0.8	0.2	-2.0	-0.5	-0.7	0.7	-0.6	-0.6	0.0	-0.3	-0.2	-0.9	-0.4
Medication: Atorvastatin	0.5	0.6	1.9	1.4	0.8	0.0	0.8	0.5	1.0	1.1	0.3	1.1	-0.2	0.6	0.2	-0.1
Alcohol drinker status: Previous	0.5	0.6	2.7	-1.6	-0.3	-0.6	-0.6	-1.1	-0.4	-0.4	-0.9	-0.1	-0.0	-0.8	-0.8	-0.4
Depressed Affect (Nagel 2018)	0.4	0.8	3.6	-1.1	-0.6	-1.9	-0.8	-0.2	0.7	-1.0	0.2	-0.9	-0.6	-1.2	-0.7	-0.3
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	-0.5	-0.1	-0.5	-0.1	-1.1	-0.7	-0.6	-1.1	-0.2	0.1	0.1	-0.8	-1.3
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.9	-0.5	-0.7	-0.8	-0.5	-0.8	0.3	-1.4	-0.6	-1.2	0.4	-0.4	-0.7	-1.2
Number of treatments/medications taken	0.4	0.8	3.0	1.2	0.6	0.7	0.5	1.1	1.7	0.7	1.1	0.6	-0.3	0.4	-0.1	0.8
Sensitivity / hurt feelings	0.4	0.7	1.3	-0.4	-0.9	-0.7	-0.7	-0.5	-0.8	-1.1	-0.8	-1.0	-0.5	-0.8	-1.2	-0.9
Hand grip strength (right)	0.4	1.1	2.9	-0.7	1.4	1.7	0.8	0.6	-0.3	0.8	0.2	1.0	1.5	0.7	1.3	1.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.2	-0.7	0.4	-0.1	0.6	0.7	-0.4	0.9	1.1	0.9	-0.3	0.3	0.8	-0.4
Chronic bronchitis/emphysema (father)	0.4	0.5	1.2	1.0	1.0	-0.3	1.1	0.4	0.5	0.7	0.2	1.1	0.3	0.7	0.2	0.3
High blood pressure (mother)	0.4	0.6	1.5	-1.2	-0.7	-0.1	-0.2	-1.2	-0.2	-1.0	-0.6	-0.7	-1.0	-0.5	-0.7	-0.8
Waist circumference	0.4	1.4	4.6	-0.6	0.1	-0.8	-0.6	-1.4	1.4	-2.1	-1.2	-1.4	-1.4	-0.4	-1.5	-0.8
Forced vital capacity (FVC)	0.4	1.4	4.8	-2.2	-0.9	-0.9	-1.1	-1.7	0.7	-1.0	-0.9	-0.8	-0.6	-1.4	-0.2	-1.2
Number of live births	0.4	0.5	1.4	0.8	0.7	-0.0	1.2	0.4	-0.9	0.4	1.0	0.5	-0.1	0.8	1.0	-0.2
Qualifications: A levels/AS levels or equivalent	0.4	0.8	3.4	0.2	-0.6	-0.5	-0.3	-0.7	1.2	-1.2	-0.2	-1.1	1.8	-0.4	0.1	-1.2
Hair/balding pattern: Pattern 4	0.4	1.1	4.0	-0.5	0.3	-2.0	-0.9	-1.8	-0.6	-1.0	-1.5	-0.5	0.4	-0.2	-1.1	0.0
Blood clot in the leg (DVT)	0.4	0.5	1.4	-0.6	-0.9	0.3	-1.2	-0.3	0.9	-0.3	0.5	-0.2	0.1	-1.1	-0.0	1.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	4.9	-1.2	-0.1	0.2	-0.2	-0.4	-2.2	0.6	-0.6	0.7	-0.6	-0.4	0.8	-0.2
Mean time to correctly identify matches	0.4	0.8	1.7	-0.7	-0.9	0.1	-1.1	-0.9	-1.2	-1.3	-1.1	-1.1	-0.8	-0.4	-0.8	-0.2
Supplements: Vitamin C	0.4	0.5	1.3	-0.3	-1.1	-0.6	-0.9	0.1	1.1	-0.3	0.6	-0.4	-0.8	-0.6	0.4	0.6
Commuting to job workplace: Walk	0.4	0.4	1.8	-0.4	0.2	-0.9	0.1	-0.7	-1.1	-0.1	-1.3	-0.1	0.5	-0.1	-0.3	-0.6
Illnesses of father: None of the above (group 1)	0.4	0.6	1.8	-0.8	-0.3	0.8	-0.9	-0.6	-1.4	-0.3	-1.1	-0.1	-1.0	-0.6	0.1	0.4
Wears glasses or contact lenses	0.4	0.5	2.1	0.3	1.1	-0.6	1.0	-0.5	1.5	-0.4	-0.5	0.1	-0.3	1.1	-0.2	0.0
Hearing aid user	0.4	0.5	2.0	-0.1	1.4	-0.3	1.1	0.5	0.5	0.5	0.3	0.9	0.7	0.6	0.2	0.6
High cholesterol (Self-reported)	0.4	0.7	2.1	-0.4	-1.5	-0.2	-0.8	-0.6	-0.4	-0.0	-0.2	-0.7	-0.8	-0.9	-1.4	-1.4
Medication: Lisinopril	0.4	0.5	1.0	1.0	1.0	-0.1	1.0	0.2	1.0	-0.3	0.1	0.1	1.0	0.7	0.3	0.9
Illnesses of father: High blood pressure	0.4	0.5	4.3	0.5	-0.0	-0.7	0.2	-0.2	2.1	-0.4	-0.1	-0.7	-0.2	0.3	-0.6	-0.3
Irritability	0.4	0.7	5.7	-0.5	-0.6	-2.4	-0.5	-0.0	0.7	-0.8	0.4	-0.7	-0.3	-0.7	-0.1	0.0
Commuting to job workplace: Cycle	0.4	0.5	2.0	-1.1	-0.3	0.8	0.0	-0.6	-1.4	-0.0	-0.7	0.2	0.1	-0.5	-0.0	-0.8
Pain experienced in last month	0.4	0.6	4.9	-0.5	-0.6	0.4	-0.2	-0.4	-2.2	0.4	0.1	0.3	-0.9	-0.2	0.1	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.3	-0.8	-0.8	0.6	-1.1	-0.2	0.8	-0.3	0.4	-0.2	0.0	-1.1	-0.1	0.9
Heart disease (siblings)	0.4	0.5	2.8	-0.5	0.5	-1.7	-0.1	-0.5	0.7	0.5	-0.7	0.6	0.2	-0.3	-1.2	0.0
Bipolar Disorder (2018)	0.3	0.5	4.2	-0.2	0.2	0.7	0.2	0.5	-2.0	0.4	0.3	0.3	-1.1	0.5	0.4	0.3
Breast Cancer	0.3	0.8	2.3	0.7	-0.5	-0.7	-0.9	-1.0	-0.7	-0.7	-1.5	-0.8	0.2	-0.5	-1.3	-1.2
Bipolar Disorder (2011)	0.3	0.3	2.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.4	-1.6	-0.4	-0.5	-0.6
HbA1C	0.3	0.4	1.4	0.4	-0.6	1.2	-0.9	-0.5	-0.3	0.1	-0.1	0.0	0.8	-0.5	-0.0	0.9
BMI	0.3	1.7	5.9	-0.5	-0.1	-0.3	-0.9	-1.8	0.7	-2.4	-2.0	-1.5	-1.3	-0.3	-1.8	-0.9
Hand grip strength (left)	0.3	0.7	3.1	-0.2	1.3	1.8	0.5	-0.0	-0.2	0.2	-1.2	0.5	1.0	0.8	0.7	0.5
Angina	0.3	0.4	1.6	0.1	-0.6	-0.9	-0.6	0.5	0.0	-0.1	-0.4	-0.5	-1.1	-0.6	-1.3	-0.0
Diabetes (mother)	0.3	0.4	2.2	0.9	0.7	0.3	0.6	0.5	-0.5	0.5	0.6	0.1	1.5	0.4	0.5	0.1
Fed-up feelings	0.3	0.6	3.0	0.3	0.5	-0.8	0.6	1.2	0.4	0.6	1.7	0.4	-0.2	0.0	0.7	1.0
Taking other prescription medications	0.3	0.5	1.9	0.5	-0.2	0.3	-0.7	0.3	1.4	-0.5	0.6	-0.6	-0.9	-0.5	-0.8	0.7
Stomach or abdominal pain in last month	0.3	0.4	1.4	1.2	0.8	0.0	0.9	1.0	-0.0	0.7	-0.4	0.4	0.0	0.9	0.1	0.2
Supplements: Glucosamine	0.3	0.4	1.0	1.0	0.5	0.1	0.6	-0.2	1.0	0.7	0.4	0.9	-0.7	0.7	0.6	-0.1
Body mass index (BMI)	0.3	1.3	3.9	-0.6	0.1	-0.9	-0.5	-1.1	1.2	-2.0	-1.4	-1.2	-1.4	-0.2	-1.6	-0.9
Nervous feelings	0.3	0.6	2.6	-0.3	-1.0	-1.6	-0.9	-0.3	0.1	-0.2	-0.7	-0.5	1.0	-0.7	-0.8	-0.7
Hearing difficulty/problems with background noise	0.3	0.5	3.7	0.2	0.1	-0.2	0.4	-0.0	-1.9	-0.6	-0.1	-0.9	-0.5	0.3	-0.9	-0.7
Hair/balding pattern: Pattern 2	0.3	0.4	0.9	0.0	0.6	0.9	0.9	0.9	-0.8	0.1	0.1	0.1	0.8	0.4	0.9	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.8	-1.3	-0.3	0.5	-0.6	-1.0	-1.1	-1.3	-1.3	-0.4	-0.4	-0.7	0.1	-0.4
Qualifications: None of the above	0.3	0.7	2.4	0.3	0.7	-1.2	0.4	0.7	1.1	0.4	0.8	0.5	-0.9	0.6	-0.4	1.6
Financial difficulties in last 2 years	0.3	0.5	1.2	1.1	0.7	0.7	0.6	0.7	-0.5	0.8	-0.6	0.9	-0.4	0.8	0.0	0.6
Mouth/teeth dental problems	0.3	0.4	2.1	-0.7	-0.2	1.2	-0.1	0.3	-0.1	0.5	0.1	0.5	-1.5	-0.2	0.4	-0.2
Pain all over the body in last month	0.3	0.3	0.9	0.3	0.6	-0.6	0.0	-0.6	1.0	-0.8	-0.6	-0.6	0.3	0.1	-0.6	0.1
Medication: Simvastatin	0.3	0.4	1.7	0.1	-0.8	-0.4	-0.7	-0.9	-0.0	-0.2	-0.4	-0.6	-0.4	-0.3	-1.3	-0.6
Neuroticism score	0.3	0.6	4.5	-0.7	-0.6	-2.1	-0.7	0.0	0.8	-0.3	-0.2	-0.5	-0.4	-0.9	-0.7	-0.3
Falls in the last year	0.3	0.5	1.2	-0.4	-1.1	-0.5	-0.7	-0.3	0.0	-0.6	0.1	-1.0	-1.0	-1.0	-0.8	-0.2
Noisy workplace	0.3	0.4	1.2	-0.2	0.9	-0.8	0.7	1.1	0.3	0.3	0.2	0.6	0.1	0.5	0.8	0.5
Prospective memory result	0.3	0.4	1.6	-0.2	-0.4	0.2	-0.0	-0.1	-1.3	-1.0	-0.9	-0.9	0.5	-0.3	-0.6	0.7
Illnesses of mother	0.3	0.3	1.3	0.2	-1.1	-0.3	-1.1	0.5	-0.3	-0.4	-0.6	-0.4	-0.4	-0.6	-0.5	0.0
Exposure to tobacco smoke at home	0.3	0.3	2.9	0.1	0.4	-0.0	0.1	-0.6	1.7	0.1	-0.4	0.3	0.7	0.2	0.3	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.4	0.6	0.9	-1.0	0.4	1.0	0.3	0.4	0.6	0.4	1.2	0.5	0.5	0.9
Birth weight of first child	0.3	0.5	1.3	0.6	0.3	0.2	0.7	-0.1	0.3	1.0	0.4	1.0	0.3	0.8	1.1	0.8
Headache pain in last month	0.3	0.5	3.3	0.1	-0.1	-1.8	-0.7	-0.4	1.0	0.2	0.2	0.4	0.3	-0.6	-0.4	0.3
Gout (self-reported)	0.3	0.5	1.9	1.4	-0.3	1.1	0.0	0.3	-0.7	-0.8	0.4	-0.5	1.0	0.3	-0.0	-0.4
Medication: Amlodipine	0.3	0.5	1.8	0.1	-0.3	0.4	-0.1	1.2	0.4	-0.8	1.2	-1.3	0.3	-0.3	0.1	-0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.6	0.7	0.7	0.5	0.7	0.7	-0.8	0.7	0.0	0.6	-0.7	0.4	0.4	0.4
Wheeze or whistling in the chest in last year	0.3	0.5	2.1	1.4	0.2	1.2	0.1	0.4	-1.0	0.2	-0.0	0.1	0.6	0.2	-0.0	1.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	4.2	0.3	-0.0	-0.4	0.1	-0.0	-2.1	0.2	-0.0	-0.0	0.2	-0.0	-0.2	-0.2
Neck or shoulder pain in last month	0.3	0.5	1.4	-1.1	-0.1	-1.1	-0.3	-0.5	1.2	-0.6	-0.8	-0.1	0.1	-0.4	-0.4	0.7
Angina (self-reported)	0.3	0.3	1.3	0.1	-0.5	-1.1	-0.5	0.6	0.1	0.0	-0.1	-0.4	-0.8	-0.6	-1.1	0.1
Medication: Seretide 50 evohaler	0.3	0.4	2.0	0.4	0.3	0.7	0.4	1.1	-1.4	0.2	0.0	0.2	0.6	0.2	0.2	0.5
Suffer from ‘nerves’	0.3	0.5	1.2	-0.8	-1.1	-1.1	-1.1	0.2	0.9	0.4	0.1	-0.0	0.0	-1.1	-0.2	0.1
Overall health rating	0.3	0.6	2.4	-0.2	0.0	-0.8	-0.7	-0.6	1.6	-0.9	-0.8	-0.7	0.1	-0.6	-1.3	-0.1
Had major operations	0.3	0.3	1.5	0.5	0.4	-0.2	0.2	-1.2	0.7	-0.3	-0.5	-0.1	0.9	0.3	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.4	0.1	1.6	0.4	1.3	-0.1	1.3	0.4	-0.0	0.8	0.5	0.9	0.9	0.3
Osteoporosis (self-reported)	0.3	0.4	1.6	-0.6	-0.4	0.9	-0.4	-0.9	-1.2	-0.5	-0.6	-0.2	-0.1	-0.5	-0.5	-0.1
Leg fat percentage (left)	0.3	1.0	2.6	-0.4	0.0	-1.4	-0.6	-1.2	1.3	-1.6	-1.1	-0.8	-1.1	-0.2	-1.3	-0.1
Age started oral contraceptive pill	0.3	0.4	1.3	-1.0	-0.3	-1.1	0.0	0.1	-1.1	0.6	0.5	0.2	0.4	-0.5	0.0	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.5	0.1	-0.5	0.5	-0.3	-0.2	0.4	-0.6	-0.3	-0.8	-0.6	-0.3	-1.2	-0.7
Bipolar Disorder or Schizophrenia	0.2	0.4	2.5	-0.4	0.4	0.2	0.6	0.5	-0.7	0.6	0.1	0.3	-1.6	0.6	0.5	-0.3
Worry (Nagel 2018)	0.2	0.3	1.2	-0.4	-0.2	-0.5	-0.2	0.5	1.1	0.9	1.0	0.4	0.5	-0.3	0.4	0.5
Ovarian Cancer	0.2	0.3	1.3	0.4	0.1	0.7	0.1	-0.4	-1.1	0.9	0.5	0.7	-0.4	0.6	0.2	0.3
Mean Putamen Volume	0.2	0.2	1.6	-0.6	0.3	-0.3	0.3	0.1	0.0	-0.1	-0.4	0.6	1.3	0.1	0.2	0.1
Neuroticism (2016)	0.2	0.2	0.9	-0.3	-0.5	0.5	-0.7	-0.9	-0.2	-0.4	0.2	-0.5	0.2	-0.5	-0.3	0.3
Schizophrenia (2014)	0.2	0.4	2.9	-0.3	0.5	0.5	0.4	0.5	0.5	0.5	0.1	0.2	-1.7	0.5	0.6	-0.4
Ulcerative Colitis	0.2	0.3	0.9	-0.2	-0.5	-0.9	-0.5	-0.2	-0.9	0.1	-0.8	0.2	0.2	-0.5	-0.7	-0.1
Heel T-Score	0.2	1.8	5.0	1.0	2.1	-0.3	2.2	1.1	-1.5	1.1	0.4	1.2	0.4	1.7	1.7	-0.6
Waist Hip Ratio (WHR)	0.2	0.7	2.4	-0.8	-0.3	-0.5	-0.7	-1.0	1.0	-1.1	-0.9	-0.8	-1.5	-0.8	-0.6	-0.2
Hearing difficulty/problems: Yes	0.2	0.3	1.5	0.6	0.8	-1.2	0.7	0.2	0.3	0.2	-0.4	0.3	-0.0	0.5	-0.8	-0.4
Systolic blood pressure, automated reading	0.2	0.7	2.4	1.5	1.3	0.7	1.1	0.0	0.4	-0.0	0.8	0.1	0.6	1.3	0.6	0.1
Leg fat-free mass (left)	0.2	0.9	3.5	0.5	1.9	1.0	1.3	0.9	1.1	0.3	0.1	0.6	0.5	1.5	0.4	0.9
Trunk fat percentage	0.2	0.6	3.6	0.4	1.2	-0.8	0.4	-0.4	1.9	-0.8	-0.4	-0.2	-0.4	0.6	-0.6	0.4
Average weekly fortified wine intake	0.2	0.3	1.4	0.4	0.5	-0.6	0.3	0.6	1.2	-0.2	0.8	-0.3	-0.1	0.3	0.3	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-0.7	0.7	0.8	0.4	-0.5	-0.2	0.3	-0.6	1.0	0.5	0.1	1.1	0.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	0.1	0.2	0.9	0.1	0.3	-0.4	0.5	0.6	0.8	0.2	0.3	0.7	0.1
Leg predicted mass (left)	0.2	0.9	3.4	0.5	1.8	0.9	1.3	0.7	1.1	0.2	0.1	0.6	0.5	1.4	0.4	0.8
Had other major operations	0.2	0.2	0.7	0.3	0.7	0.1	0.6	0.8	0.3	-0.4	0.2	-0.5	0.1	0.3	0.2	-0.3
Diabetes (self-reported)	0.2	0.2	1.2	0.7	0.3	-0.6	0.1	-0.4	0.7	-0.5	-0.1	-0.3	1.1	0.2	-0.2	0.1
Fluid intelligence score	0.2	0.5	1.8	0.6	0.8	-0.6	0.5	-0.9	-0.2	-0.4	-1.3	0.1	0.7	0.6	-0.2	-0.9
Arm fat percentage (right)	0.2	0.9	4.8	0.6	0.8	-0.8	0.0	-0.6	2.2	-1.4	-0.9	-0.6	-0.7	0.4	-0.9	0.2
Medication: Lansoprazole	0.2	0.2	1.0	-0.2	-0.0	-0.3	-0.4	-0.4	-0.2	0.6	0.1	0.4	0.5	-0.1	-0.4	-1.0
Arm fat mass (right)	0.2	0.9	2.8	-0.1	0.8	-1.1	-0.1	-0.8	1.7	-1.6	-1.1	-0.9	-0.9	0.2	-1.2	-0.4
Standing height	0.2	2.4	4.8	0.5	2.2	1.3	1.8	1.5	0.8	1.7	1.3	1.5	1.9	1.6	1.8	1.6
Length of working week for main job	0.2	0.3	1.5	0.1	0.1	1.2	0.5	0.5	-0.2	-0.2	-0.2	0.1	0.9	0.5	0.3	0.4
Breastfed as a baby	0.2	0.3	1.6	-0.4	-0.3	-0.4	-0.1	0.0	-0.1	0.6	0.5	0.2	-1.3	-0.4	-0.6	-0.6
Birth weight	0.2	0.3	2.1	-0.2	0.1	0.6	0.4	-0.7	1.4	0.5	0.2	0.4	-0.4	0.4	0.7	0.2
Forced vital capacity (FVC), Best measure	0.2	0.7	2.2	-1.5	-0.8	-0.5	-0.8	-1.4	0.4	-0.7	-0.8	-0.5	-0.0	-1.0	-0.1	-0.9
Body fat percentage	0.2	0.8	3.3	0.1	0.7	-1.1	-0.1	-0.8	1.8	-1.4	-0.7	-0.7	-0.7	0.2	-1.1	0.1
Leg fat percentage (right)	0.2	0.8	3.1	0.1	0.4	-1.2	-0.3	-1.1	1.8	-1.5	-0.8	-0.5	-0.5	0.1	-1.0	0.3
Comparative body size at age 10	0.2	0.5	1.4	0.8	-0.1	-0.6	-0.3	-1.0	-0.1	-1.1	-1.2	-0.4	0.6	0.1	-0.8	-0.7
Number of full brothers	0.2	0.3	1.1	0.4	0.0	-0.9	0.5	0.4	-0.1	0.2	0.1	-0.3	-1.1	0.6	-0.2	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	1.4	0.3	-0.1	-0.2	-0.2	0.2	0.7	-0.2	-0.7	-0.1	1.2	0.3	-0.2	0.3
Eye problems/disorders: None of the above	0.2	0.2	0.6	-0.6	0.3	-0.5	-0.2	-0.2	-0.5	-0.2	-0.7	0.2	0.5	-0.1	-0.2	0.8
Medication: Ibuprofen	0.2	0.3	1.9	-0.6	-0.1	-1.4	0.1	-0.1	-0.3	-0.4	-0.4	-0.4	-0.3	-0.2	-0.0	-0.9
Heart disease (mother)	0.2	0.3	0.8	0.1	0.8	0.2	0.5	0.2	0.9	0.1	0.4	0.0	0.8	0.5	-0.3	0.8
Whole body fat mass	0.2	0.7	3.5	-0.1	1.0	-0.8	0.1	-0.5	1.9	-1.2	-0.6	-0.5	-0.7	0.4	-0.8	0.2
Leg fat mass (right)	0.2	0.6	3.3	-0.2	0.9	-0.9	0.1	-0.5	1.8	-1.2	-0.6	-0.4	-0.6	0.4	-0.8	0.4
Pulse rate, automated reading	0.2	0.5	2.0	1.3	0.1	0.5	0.2	-0.2	-0.7	-0.2	-0.7	-0.6	1.4	0.4	-0.6	1.0
Arm fat percentage (left)	0.2	0.8	3.2	0.3	0.7	-0.9	-0.1	-0.8	1.8	-1.4	-0.9	-0.7	-0.8	0.3	-1.0	0.1
Diabetes diagnosed by doctor	0.2	0.3	0.9	0.1	-0.1	-0.8	-0.4	-0.4	0.8	-0.9	-0.1	-0.7	0.6	-0.2	-0.5	-0.6
Friendships satisfaction	0.2	0.3	1.0	-0.4	-0.8	-0.1	-0.3	0.8	-0.4	0.6	1.0	0.4	-0.0	-0.3	-0.0	0.0
Breast cancer (self-reported)	0.2	0.3	1.2	1.0	0.0	-0.6	0.1	-0.9	0.1	-0.1	-0.2	0.3	1.1	-0.0	0.0	-0.2
Arm fat mass (left)	0.2	0.8	2.9	-0.0	1.0	-0.9	0.1	-0.7	1.7	-1.3	-0.9	-0.6	-0.9	0.4	-0.9	-0.1
Commuting to job workplace: Public transport	0.2	0.3	1.4	0.0	0.0	0.5	-0.1	-0.4	-1.0	0.4	-1.2	0.2	0.4	0.2	0.4	-0.2
Ever smoked	0.2	0.3	1.6	-0.8	0.3	-0.1	0.2	1.3	0.0	-0.2	0.6	-0.1	-0.8	-0.1	-0.1	0.2
Diastolic blood pressure, automated reading	0.2	0.6	1.6	0.8	1.2	-0.1	0.4	-0.5	0.6	-0.8	-1.2	-0.3	1.0	0.9	-0.3	-0.3
Supplements: Calcium	0.2	0.3	1.0	-0.0	-0.0	1.0	0.4	0.9	-0.5	0.0	0.6	0.0	0.2	0.4	-0.0	-0.9
Impedance of whole body	0.2	1.0	2.3	1.0	0.5	-0.4	0.6	0.6	0.6	1.3	1.4	1.0	1.5	0.4	1.4	1.2
Leg fat mass (left)	0.2	0.7	2.5	-0.5	0.7	-1.1	-0.1	-0.6	1.6	-1.4	-0.8	-0.6	-1.0	0.2	-1.0	0.2
Neuroticism (Nagel 2018)	0.1	0.3	1.2	-0.5	-0.1	-1.1	-0.1	0.7	0.7	-0.3	1.0	-0.7	0.5	-0.5	0.0	0.1
Schizophrenia (2018)	0.1	0.3	1.4	-0.3	0.5	-0.5	0.3	0.3	0.7	0.4	-0.1	0.1	-1.2	0.4	0.2	-0.6
Alzheimer’s Disease (including proxy)	0.1	0.2	0.8	-0.0	0.5	0.0	0.3	-0.0	-0.5	-0.3	-0.6	0.4	0.2	0.7	0.2	-0.9
Ulcerative Colitis (UC)	0.1	0.3	1.6	0.6	0.1	-1.3	0.2	0.1	0.7	0.4	0.0	0.4	0.6	-0.1	-0.1	0.1
Triglycerides	0.1	0.1	0.6	0.2	-0.2	-0.6	-0.0	0.6	0.1	0.4	0.0	-0.3	0.8	0.3	-0.4	-0.2
Height	0.1	1.1	2.5	0.1	1.2	1.6	1.1	0.8	0.1	1.0	1.4	0.8	1.1	1.0	1.5	1.1
Systolic Blood Pressure	0.1	0.5	2.1	1.5	0.7	1.0	0.9	0.1	0.6	-0.5	-0.0	-0.3	0.7	1.1	0.3	-0.5
Smoking Status	0.1	0.3	1.2	-1.0	-0.2	0.0	-0.3	0.5	-0.8	-0.8	-0.1	-0.6	-1.1	-0.5	-0.4	0.1
Cardiovascular Disease	0.1	0.3	2.1	0.4	0.0	-0.4	0.2	0.1	1.5	-0.2	0.2	-0.2	0.8	0.1	-0.7	-0.1
Neuroticism	0.1	0.2	1.2	-0.1	0.1	-1.0	0.2	0.1	1.1	0.0	-0.1	0.1	-0.3	-0.0	-0.1	-0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.4	-0.3	-0.1	-0.7	0.1	0.6	0.0	-0.3	0.3	-0.4	-0.2	-0.2	-0.6	-0.6
Impedance of leg (right)	0.1	0.6	2.0	0.6	0.1	-1.2	0.1	-0.2	0.6	0.6	0.9	0.6	1.4	-0.1	0.9	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.6	0.2	0.0	0.5	0.3	0.5	0.1	0.3	0.2	0.1	-0.2	0.2	0.0	0.8
Age when periods started (menarche)	0.1	0.4	1.0	0.3	0.7	0.2	0.7	0.5	0.6	0.8	0.2	1.0	-0.6	0.6	0.6	0.5
Serious illness, injury or assault to yourself	0.1	0.1	0.4	0.1	0.2	-0.7	-0.2	0.0	0.5	-0.4	-0.2	-0.6	0.4	-0.3	-0.4	-0.4
Impedance of leg (left)	0.1	0.5	3.2	-0.3	-0.8	-1.8	-0.7	-0.6	0.1	0.2	0.4	-0.0	0.2	-0.9	0.2	0.3
Trunk fat mass	0.1	0.6	3.2	0.1	1.3	-0.6	0.4	-0.5	1.8	-0.8	-0.5	-0.2	-0.5	0.7	-0.6	0.4
Past tobacco smoking	0.1	0.1	0.5	0.5	-0.2	0.3	0.0	-0.7	0.4	0.4	-0.3	0.2	0.3	0.2	0.3	-0.1
Weight	0.1	0.5	2.3	-0.3	1.1	-0.2	0.3	-0.3	1.5	-1.1	-0.6	-0.4	-0.5	0.5	-0.6	-0.1
Hip circumference	0.1	0.4	1.5	-0.3	0.3	-0.2	-0.2	-0.8	0.9	-1.2	-0.8	-0.7	-0.4	0.0	-0.9	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	-0.1	0.1	-0.2	0.6	0.6	0.1	0.4	0.5	0.1	-0.2	0.5	0.4	0.2
Tense / ‘highly strung’	0.1	0.2	0.9	-0.1	-0.3	-0.5	-0.3	-0.2	-0.1	0.1	0.0	-0.6	0.9	-0.4	-0.5	0.0
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.5	-0.3	-0.4	0.6	-0.1	-0.5	-0.1	-0.2	-0.5	-0.1	0.7	-0.0	0.4	-0.7
Worry too long after embarrassment	0.1	0.1	0.5	-0.4	-0.0	0.7	-0.1	-0.6	-0.2	-0.2	0.1	-0.3	0.6	0.2	0.2	-0.2
Qualifications: College or University degree	0.1	0.2	1.7	-0.1	-0.2	-0.2	0.2	-0.1	-0.1	-0.6	-0.2	-0.4	0.9	-0.2	0.3	-1.3
Alcohol intake frequency.	0.1	0.3	0.8	-0.1	0.9	-0.8	0.9	-0.2	0.2	0.1	-0.6	0.5	0.6	0.4	-0.3	-0.3
Knee pain experienced in last month	0.1	0.2	0.6	0.7	0.4	0.2	0.6	0.7	0.8	0.1	0.4	-0.2	0.2	0.6	0.1	0.5
Smoking status: Previous	0.1	0.2	0.7	0.7	0.7	0.4	0.4	0.8	-0.2	-0.1	0.5	0.1	0.2	0.4	0.1	0.5
Whole body fat-free mass	0.1	0.4	1.8	-0.1	1.3	0.9	0.9	0.3	0.5	-0.0	0.0	0.3	0.3	1.0	0.3	0.6
Leg fat-free mass (right)	0.1	0.5	1.7	0.1	1.3	0.9	0.9	0.7	0.8	0.2	-0.1	0.4	-0.1	1.1	0.1	0.4
Whole body water mass	0.1	0.4	1.9	-0.1	1.4	0.9	0.9	0.3	0.5	0.0	0.0	0.3	0.3	1.0	0.3	0.6
Leg predicted mass (right)	0.1	0.5	1.8	0.1	1.4	0.9	0.9	0.7	0.7	0.2	-0.1	0.4	-0.1	1.1	0.1	0.4
Number of self-reported non-cancer illnesses	0.1	0.3	1.5	0.2	0.0	-0.3	-0.6	-0.1	1.2	-0.4	0.2	-0.5	-0.5	-0.5	-0.6	-0.1
Guilty feelings	0.1	0.2	0.7	-0.5	-0.4	-0.8	-0.3	-0.1	-0.0	0.6	-0.3	0.4	0.6	-0.3	-0.4	0.1
Basal metabolic rate	0.1	0.4	1.9	-0.1	1.4	0.5	0.8	0.2	0.9	-0.2	-0.2	0.1	0.1	0.9	0.1	0.4
Cholesterol lowering medication	0.1	0.1	0.7	0.0	-0.1	0.0	-0.3	-0.2	0.1	0.8	0.4	0.4	-0.2	-0.2	-0.1	-0.2
Hair Pigment	0.0	0.9	4.0	0.6	1.0	0.5	0.7	1.4	2.0	0.4	1.1	0.5	0.2	0.9	0.8	0.7
Tanning	0.0	0.4	3.2	1.8	0.1	-0.7	0.4	0.4	-0.4	-0.0	0.1	-0.7	-0.1	0.6	-0.3	0.6
Trunk fat-free mass	0.0	0.3	1.2	-0.4	1.1	0.7	0.6	-0.0	0.5	-0.3	-0.1	0.0	0.3	0.7	0.2	0.4
Trunk predicted mass	0.0	0.3	1.2	-0.4	1.1	0.8	0.6	0.1	0.5	-0.2	-0.0	0.1	0.3	0.7	0.3	0.4
Arm fat-free mass (right)	0.0	0.1	0.6	-0.8	0.6	-0.0	0.2	-0.3	0.3	-0.6	-0.1	-0.3	-0.4	0.2	-0.2	-0.0
Arm predicted mass (right)	0.0	0.2	1.0	-1.0	0.5	-0.1	0.1	-0.4	0.1	-0.8	-0.4	-0.4	-0.5	0.1	-0.4	-0.3
Arm fat-free mass (left)	0.0	0.2	1.1	-0.3	1.1	0.2	0.7	0.1	0.7	-0.2	-0.1	0.1	-0.1	0.7	0.1	0.1
Arm predicted mass (left)	0.0	0.2	0.6	-0.7	0.8	0.1	0.3	-0.1	0.4	-0.5	-0.1	-0.2	-0.4	0.4	-0.1	-0.1

Hub : Genes

CCDC102A

Models

Trait associations