Best TWAS P=1.36e-08 · Best GWAS P=4.77e-11 conditioned to 1.89e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | SYNGR2 | 0.35 | 0.03 | enet | 14 | 0.12 | 2.6e-04 | -5.0 | 5.2 | 2.2e-07 | 0.03 | 0.09 | 0.06 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TMC6 | 0.11 | 0.02 | lasso | 2 | 0.05 | 1.6e-06 | -5.2 | -5.7 | 1.4e-08 | 0.02 | 0.06 | 0.54 | TRUE |