Best TWAS P=2.65e-09 · Best GWAS P=1.86e-09 conditioned to 0.139
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | NARF | 0.17 | 0.11 | enet | 19 | 0.13 | 1.0e-10 | -5.4 | 6.0 | 2.7e-09 | -0.81 | 0.10 | 0.90 | TRUE |
| 2 | GTEx | Artery Aorta | NARF | 0.25 | 0.23 | lasso | 10 | 0.22 | 1.4e-12 | -6.0 | 5.6 | 2.1e-08 | -0.98 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Brain Cerebellum | NARF | 0.20 | 0.07 | enet | 19 | 0.03 | 4.2e-02 | -4.3 | 5.6 | 1.9e-08 | -0.76 | 0.02 | 0.81 | FALSE |
| 4 | GTEx | Nerve Tibial | WDR45B | 0.14 | 0.03 | enet | 41 | 0.06 | 4.4e-05 | -4.6 | 5.2 | 2.4e-07 | -0.16 | 0.27 | 0.23 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FN3K | 0.02 | 0.01 | blup | 32 | 0.03 | 3.9e-06 | 3.6 | -5.2 | 2.5e-07 | 0.04 | 0.07 | 0.86 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | FN3K | 0.03 | 0.01 | blup | 32 | 0.02 | 4.0e-03 | 4.6 | -5.7 | 1.0e-08 | 0.06 | 0.01 | 0.72 | TRUE |