Best TWAS P=4.55e-23 · Best GWAS P=8.47e-28 conditioned to 1.47e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | WDR49 | 0.09 | 0.02 | bslmm | 402 | 0.04 | 9.3e-06 | 7.5 | -9.3 | 1.7e-20 | 0.03 | 0.07 | 0.93 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | SERPINI1 | 0.23 | 0.01 | enet | 39 | 0.03 | 3.0e-02 | 8.3 | -7.3 | 4.0e-13 | -0.01 | 0.05 | 0.78 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | PDCD10 | 0.08 | 0.04 | lasso | 7 | 0.05 | 1.3e-03 | 9.9 | 9.9 | 4.5e-23 | -0.01 | 0.04 | 0.94 | TRUE |
| 4 | GTEx | Thyroid | MECOM | 0.13 | 0.10 | lasso | 4 | 0.08 | 6.1e-07 | 4.9 | 5.6 | 1.9e-08 | 0.10 | 0.86 | 0.01 | FALSE |
| 5 | GTEx | Thyroid | SERPINI1 | 0.08 | 0.04 | lasso | 5 | 0.05 | 1.9e-04 | 8.4 | -8.8 | 9.0e-19 | -0.01 | 0.07 | 0.92 | FALSE |
| 6 | METSIM | Adipose | SERPINI1 | 0.04 | 0.02 | enet | 25 | 0.02 | 1.8e-04 | 7.5 | -8.0 | 1.8e-15 | -0.01 | 0.06 | 0.90 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SERPINI1 | 0.03 | 0.01 | blup | 79 | 0.00 | 1.2e-01 | -3.4 | -8.5 | 1.7e-17 | 0.00 | 0.02 | 0.42 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | MECOM | 0.10 | 0.07 | lasso | 2 | 0.05 | 6.2e-06 | 8.3 | 9.7 | 4.0e-22 | 0.26 | 0.24 | 0.73 | TRUE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | PDCD10 | 0.08 | 0.04 | enet | 2 | 0.04 | 1.4e-04 | 7.4 | 7.5 | 4.5e-14 | 0.03 | 0.09 | 0.17 | FALSE |