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chr3:166,503,411-170,078,232

Best TWAS P=4.55e-23 · Best GWAS P=8.47e-28 conditioned to 1.47e-18

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Skin Not Sun Exposed Suprapubic	PDCD10	0.08	0.04	lasso	7	0.05	1.3e-03	9.9	9.9	4.5e-23	-0.01	0.04	0.94	TRUE
8	The Cancer Genome Atlas	Thyroid Carcinoma	MECOM	0.10	0.07	lasso	2	0.05	6.2e-06	8.3	9.7	4.0e-22	0.26	0.24	0.73	TRUE
1	CommonMind	Brain Pre-frontal Cortex	WDR49	0.09	0.02	bslmm	402	0.04	9.3e-06	7.5	-9.3	1.7e-20	0.03	0.07	0.93	FALSE
5	GTEx	Thyroid	SERPINI1	0.08	0.04	lasso	5	0.05	1.9e-04	8.4	-8.8	9.0e-19	-0.01	0.07	0.92	FALSE
7	The Cancer Genome Atlas	Prostate Adenocarcinoma	SERPINI1	0.03	0.01	blup	79	0.00	1.2e-01	-3.4	-8.5	1.7e-17	0.00	0.02	0.42	FALSE
6	METSIM	Adipose	SERPINI1	0.04	0.02	enet	25	0.02	1.8e-04	7.5	-8.0	1.8e-15	-0.01	0.06	0.90	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	PDCD10	0.08	0.04	enet	2	0.04	1.4e-04	7.4	7.5	4.5e-14	0.03	0.09	0.17	FALSE
2	GTEx	Esophagus Gastroesophageal Junction	SERPINI1	0.23	0.01	enet	39	0.03	3.0e-02	8.3	-7.3	4.0e-13	-0.01	0.05	0.78	FALSE
4	GTEx	Thyroid	MECOM	0.13	0.10	lasso	4	0.08	6.1e-07	4.9	5.6	1.9e-08	0.10	0.86	0.01	FALSE