TWAS hub - TLR10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.0817	0.0299	0.00061	0.011	0.033	0.019	0.028	0.014	0.01400	3.4e-05	0.00160	0.00014	0.00510
2	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0880	0.0460	0.00240	0.063	0.058	0.058	NA	0.060	0.00018	3.1e-04	0.00032	NA	0.00023

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Allergy or Eczema	60.9	160.2	201.6	10.9	14.2
Hayfever, allergic rhinitis or eczema	53.6	116.3	144.0	9.4	12.0
Allergy	38.5	88.5	116.6	-7.8	-10.8
Hayfever/allergic rhinitis (self-reported)	20.3	26.9	36.8	4.1	6.1
Asthma	13.8	27.3	34.0	4.5	5.8
Asthma (self-reported)	13.4	26.7	32.6	4.5	5.7
Respiratory disease	11.4	25.4	35.7	3.9	6.0
Blood Eosinophil Count	7.5	58.1	114.5	-10.7	-1.3
Hypothyroidism (self reported)	6.6	15.1	19.1	-3.3	-4.4
Breast Cancer	6.5	15.7	18.2	3.6	4.3
Medication: Ventolin 100micrograms inhaler	5.8	7.4	8.3	2.6	2.9
Hypothyroidism/myxoedema (self-reported)	4.8	9.3	11.8	-2.6	-3.4
Glaucoma (self-reported)	4.2	4.9	5.5	-2.4	-2.1
Illnesses of mother	4.1	5.0	10.0	0.1	-3.2
Alcohol drinker status: Previous	4.1	4.7	7.1	-2.7	-1.5
Multivitamins +/- minerals	4.0	5.0	6.0	-2.0	-2.5
Hip circumference	4.0	17.4	24.2	-4.9	-3.2
BMI	3.8	21.9	28.4	-3.9	-5.3
Hand grip strength (right)	3.6	9.8	9.9	3.2	3.1
Mouth/teeth dental problems: Mouth ulcers	3.6	5.8	6.1	-2.4	-2.5
Eye problems/disorders: Diabetes related eye disease	3.5	3.8	4.2	-1.9	-2.0
Guilty feelings	3.3	4.9	7.4	-2.7	-1.6
Eye problems/disorders: Glaucoma	3.1	3.7	4.2	-1.8	-2.0
Blood Platelet Count	2.9	33.3	44.9	6.7	4.7
Alcohol intake frequency.	2.9	6.8	10.7	-3.3	-1.7
Blood White Count	2.8	20.6	24.4	4.1	4.9
Hand grip strength (left)	2.8	7.4	7.5	2.7	2.7
Breast cancer (self-reported)	2.8	3.3	3.5	-1.8	-1.9
Average weekly red wine intake	2.7	4.0	5.2	2.3	1.7
Medication: Paracetamol	2.7	4.2	6.5	1.3	2.6
Waist circumference	2.6	9.6	12.6	-3.6	-2.6
Pulse rate	2.6	4.4	6.8	2.6	1.4
Medication: Paracetamol	2.6	4.3	7.5	1.1	2.7
Systolic blood pressure, automated reading	2.5	7.4	11.0	1.9	3.3
Coronary Artery Disease (CAD)	2.4	2.9	5.0	0.9	2.2
Ulcerative Colitis	2.4	3.5	4.0	-2.0	-1.7
Blood Red Count	2.4	23.1	41.1	-6.4	-2.3
Lung FEV1/FVC ratio	2.4	12.1	15.4	-3.0	-3.9
Rheumatoid Arthritis	2.3	3.2	3.3	-1.8	-1.8
Medication: Levothyroxine sodium	2.3	3.9	4.7	-1.8	-2.2
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	4.2	-2.0	-1.3
Depression (Nagel 2018)	2.2	3.4	6.3	-2.5	-0.6
Body Mass Index (BMI) (2010)	2.2	3.1	4.0	-1.5	-2.0
HDL Cholesterol	2.2	3.7	3.8	1.9	1.9
Relative age voice broke	2.2	3.3	3.7	1.9	1.7
Medication for pain relief, constipation, heartburn	2.2	3.7	6.7	-0.9	-2.6
Weight	2.1	10.1	12.7	-3.6	-2.7
Overall health rating	2.1	4.5	9.0	-3.0	-0.0
Trunk fat mass	2.0	8.6	11.8	-3.4	-2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	4.7	-0.7	-2.2
Pulse wave peak to peak time	2.0	2.4	3.5	-1.1	-1.9
Supplements: Vitamin C	2.0	2.3	2.6	1.4	1.6
Arm fat mass (left)	2.0	8.3	10.7	-3.3	-2.4
Systolic Blood Pressure	1.9	9.7	11.4	2.8	3.4
Chest pain or discomfort	1.9	2.7	3.5	1.4	1.9
Irritability	1.9	3.1	3.8	1.6	1.9
Ever depressed for a whole week	1.9	2.3	4.0	0.7	2.0
Medication for hormone replacement therapy	1.8	2.0	3.9	2.0	0.2
High blood pressure (mother)	1.8	2.5	4.3	-0.9	2.1
Medication: Lansoprazole	1.8	2.0	2.2	1.5	1.4
Arm fat mass (right)	1.8	7.3	9.0	-3.0	-2.4
Whole body fat mass	1.8	7.3	9.6	-3.1	-2.2
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.1	3.5	-0.9	-1.9
Arm fat percentage (left)	1.8	7.2	9.2	-3.0	-2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	2.7	1.7	1.2
Diastolic blood pressure, automated reading	1.8	5.6	8.4	1.7	2.9
Mean Putamen Volume	1.7	2.0	3.2	-0.9	-1.8
Number of treatments/medications taken	1.7	3.1	4.9	1.1	2.2
Blood clot in the leg (DVT)	1.7	2.3	3.1	-1.8	-1.2
Medication: Blood pressure	1.7	3.0	4.4	1.3	2.1
Fractured/broken bones in last 5 years	1.7	2.2	4.3	0.3	2.1
Impedance of leg (right)	1.6	7.9	8.6	2.9	2.7
Trunk fat percentage	1.6	6.2	9.3	-3.0	-1.8
Average weekly fortified wine intake	1.6	1.8	3.5	-1.9	-0.5
Breastfed as a baby	1.6	2.0	2.3	-1.5	-1.3
Medication for cholesterol, blood pressure or diabetes	1.6	2.7	4.1	-1.1	-2.0
Wheeze or whistling in the chest in last year	1.6	2.9	3.9	1.4	2.0
Number of children fathered	1.6	1.8	2.3	-1.5	-1.1
Leg fat-free mass (right)	1.6	8.5	11.0	-3.3	-2.4
Back pain experienced in last month	1.6	2.3	2.8	-1.4	-1.7
Leg predicted mass (right)	1.6	8.3	10.9	-3.3	-2.4
Number of self-reported non-cancer illnesses	1.6	2.8	5.5	0.4	2.3
Alcohol drinker status: Never	1.6	1.9	3.3	-1.8	-0.7
Hearing difficulty/problems with background noise	1.5	2.4	4.2	-2.1	-0.8
Arm fat percentage (right)	1.5	6.0	7.3	-2.7	-2.2
Pulse wave Arterial Stiffness index	1.5	1.8	2.9	0.8	1.7
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	3.1	-1.8	-0.9
Medication: Aspirin	1.5	2.0	2.8	1.1	1.7
Knee pain experienced in last month	1.5	2.3	2.8	-1.7	-1.3
Past tobacco smoking	1.4	2.5	4.0	-2.0	-1.0
Medication: Simvastatin	1.4	2.1	2.4	1.3	1.6
Pulse rate, automated reading	1.4	4.6	8.1	2.8	1.0
Commuting to job workplace: Walk	1.4	1.5	1.9	1.1	1.4
Leg fat mass (left)	1.4	5.3	6.2	-2.5	-2.1
Neuroticism (Nagel 2018)	1.3	3.1	5.8	-2.4	-0.7
Alzheimer’s Disease (in father)	1.3	1.4	2.3	-1.5	-0.7
Leg fat-free mass (left)	1.3	6.9	8.4	-2.9	-2.3
Body mass index (BMI)	1.3	5.5	6.1	-2.5	-2.2
Had other major operations	1.3	1.6	3.0	-1.7	-0.5
Prospective memory result	1.3	1.6	2.5	0.8	1.6
Body fat percentage	1.3	5.1	7.1	-2.7	-1.8
Leg pain on walking	1.3	1.7	2.4	-1.0	-1.6
Smoking status: Previous	1.3	2.0	2.4	1.3	1.5
Handedness (chirality/laterality): Left-handed	1.3	1.6	3.0	-0.5	-1.7
Average weekly champagne plus white wine intake	1.3	1.8	2.6	1.1	1.6
Hearing difficulty/problems: Yes	1.2	1.8	3.5	-1.9	-0.4
Impedance of leg (left)	1.2	6.0	7.3	2.2	2.7
Leg predicted mass (left)	1.2	6.3	7.7	-2.8	-2.2
Number of incorrect matches in round	1.2	1.9	3.5	-0.6	-1.9
Comparative body size at age 10	1.2	3.4	4.8	-1.4	-2.2
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.2	-0.8	-1.5
Migraine (self-reported)	1.2	1.5	2.5	-0.7	-1.6
Leg fat mass (right)	1.2	4.5	4.9	-2.2	-2.0
Basal metabolic rate	1.2	6.7	8.4	-2.9	-2.2
Bipolar Disorder (2011)	1.1	1.0	1.8	-0.6	-1.3
Type 2 Diabetes (T2D) (2012)	1.1	1.3	2.1	-1.5	-0.7
Ever had hysterectomy (womb removed)	1.1	1.2	1.6	-1.3	-0.9
Townsend deprivation index at recruitment	1.1	1.6	2.8	0.6	1.7
Heart attack	1.1	1.4	2.2	0.7	1.5
Father’s age at death	1.1	1.4	2.3	-0.8	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	2.0	-1.4	-1.2
Lung cancer (father)	1.1	1.2	2.2	-0.6	1.5
Medication: Omeprazole	1.1	1.4	1.5	-1.2	-1.1
Had major operations	1.1	1.3	2.1	0.7	1.4
Pain experienced in last month	1.1	1.8	2.1	1.3	1.4
Diabetes (father)	1.0	1.2	1.9	-1.4	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.3	-1.5	0.5
Mouth/teeth dental problems	1.0	1.5	3.0	-0.2	1.7
Tense / ‘highly strung’	1.0	1.6	2.9	-0.6	-1.7
Worry too long after embarrassment	1.0	1.7	2.7	-1.6	-0.8
Illnesses of father: Heart disease	1.0	1.3	2.0	1.4	0.8
Whole body fat-free mass	1.0	5.4	6.8	-2.6	-2.0
Whole body water mass	1.0	5.9	7.2	-2.7	-2.1
Ever smoked	1.0	1.8	3.1	1.8	0.7
Heart attack/myocardial infarction (self-reported)	1.0	1.3	1.9	0.8	1.4
Arm predicted mass (left)	1.0	5.2	6.1	-2.5	-2.1
Maternal smoking around birth	0.9	1.4	1.8	1.4	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	3.7	0.5	-1.9
Serious illness, injury or assault to yourself	0.9	1.1	1.7	-1.3	-0.7
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.0	0.4	1.4
Number of live births	0.9	1.3	2.1	-0.8	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	1.8	-0.6	1.3
Mouth/teeth dental problems: Dentures	0.9	1.5	2.9	1.7	-0.3
Medication: Aspirin	0.9	1.1	1.9	0.6	1.4
Worry (Nagel 2018)	0.8	1.8	3.3	-1.8	-0.4
Alzheimer’s Disease (in mother)	0.8	0.9	1.1	1.1	0.8
Neuroticism	0.8	2.0	3.1	-1.8	-0.9
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.8	1.3	0.1
Stomach or abdominal pain in last month	0.8	1.0	1.3	-0.8	-1.1
Financial difficulties in last 2 years	0.8	1.1	2.2	0.1	1.5
Fluid intelligence score	0.8	1.6	2.0	1.0	1.4
Trunk predicted mass	0.8	4.7	5.2	-2.3	-2.0
Loud music exposure frequency	0.8	0.8	1.1	-0.8	1.0
Arm fat-free mass (right)	0.8	4.2	5.2	-2.3	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	1.6	-1.3	0.6
Age at first live birth	0.8	1.3	1.4	1.2	1.1
Medication: Ibuprofen	0.8	0.9	1.8	0.3	1.3
Arm fat-free mass (left)	0.8	4.0	4.9	-2.2	-1.7
Prostate Cancer	0.7	1.0	1.2	0.8	1.1
Primary Biliary Cirrhosis	0.7	1.0	1.0	-1.0	-1.0
Heel T-Score	0.7	5.4	7.1	1.9	-2.7
Type 2 Diabetes (T2D) (2018)	0.7	1.4	2.7	0.1	-1.6
Alcohol usually taken with meals	0.7	1.2	2.0	-0.7	-1.4
Qualifications: None of the above	0.7	1.5	3.0	0.1	1.7
Trunk fat-free mass	0.7	4.3	4.9	-2.2	-1.9
Worrier / anxious feelings	0.7	1.4	2.1	-1.5	0.8
Depression (self-reported)	0.7	0.9	1.6	1.3	0.3
Shortness of breath walking on level ground	0.7	0.9	1.5	-1.2	-0.5
Heart disease (mother)	0.7	0.8	1.6	0.3	1.3
Arm predicted mass (right)	0.7	3.3	4.3	-2.1	-1.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.6	-1.2	0.2
Medication: Gliclazide	0.7	0.8	1.3	-0.6	-1.1
Wears glasses or contact lenses	0.7	0.8	1.3	-0.5	1.2
Leg fat percentage (left)	0.7	2.7	3.8	-1.9	-1.3
Risk taking	0.7	1.1	2.2	-0.1	-1.5
Age started oral contraceptive pill	0.7	0.9	1.4	-0.6	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	0.9	-1.0	-0.9
Depressed Affect (Nagel 2018)	0.6	1.3	2.6	-1.6	-0.2
Age at First Birth	0.6	0.9	1.8	0.3	1.3
Neuroticism (2016)	0.6	0.8	1.3	-0.6	-1.1
Severe depression (siblings)	0.6	0.7	0.9	0.7	0.9
Taking other prescription medications	0.6	1.0	1.2	0.8	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.4	-0.2	1.2
Angina (self-reported)	0.6	0.8	1.7	0.0	1.3
Medication: Seretide 50 evohaler	0.6	0.7	1.4	0.3	1.2
Age at last live birth	0.6	0.9	1.5	0.5	1.2
Mood swings	0.6	1.1	2.2	-0.2	1.5
Schizophrenia (2018)	0.5	1.0	1.8	0.3	-1.4
Ovarian Cancer	0.5	0.6	0.8	0.9	0.7
Smoking Status	0.5	1.2	1.5	1.2	0.9
Medication: Atenolol	0.5	0.6	0.9	-0.9	0.6
Hair/balding pattern: Pattern 2	0.5	0.6	0.7	0.8	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.0	0.4	-1.4
Medication: Cholesterol lowering	0.5	0.7	1.0	0.7	1.0
Birth weight of first child	0.5	0.8	1.5	1.2	0.4
Gout (self-reported)	0.5	0.7	0.9	0.7	1.0
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.1	1.0	-0.0
Suffer from ‘nerves’	0.5	0.7	0.9	-0.8	0.9
Family relationship satisfaction	0.5	0.6	1.0	-1.0	-0.4
Long-standing illness, disability or infirmity	0.5	0.7	1.0	-0.7	1.0
Diabetes diagnosed by doctor	0.5	0.9	1.7	-0.2	-1.3
Friendships satisfaction	0.5	0.7	0.8	0.9	0.7
Qualifications: nursing, teaching	0.5	0.8	0.9	0.8	-0.9
Illnesses of father: None of the above (group 1)	0.5	0.6	1.3	1.1	-0.1
Average weekly beer plus cider intake	0.5	0.8	1.6	1.2	-0.0
Myopia	0.5	0.8	1.1	0.7	1.0
Bipolar Disorder (2018)	0.4	0.6	1.0	-1.0	-0.4
Bipolar Disorder or Schizophrenia	0.4	1.0	1.7	-0.4	-1.3
Triglycerides	0.4	0.7	1.2	-1.1	-0.5
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.1	-1.1	0.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.7	-0.5	-0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.6	0.7	-0.8
Angina	0.4	0.5	1.0	-0.2	1.0
Medication: Co-codamol	0.4	0.5	0.5	-0.6	0.7
Medication: Metformin	0.4	0.5	1.0	0.2	-1.0
Pain all over the body in last month	0.4	0.4	0.7	-0.2	0.9
Diabetes (self-reported)	0.4	0.6	0.6	-0.8	-0.7
Time employed in main current job	0.4	0.4	0.8	-0.1	0.9
Length of working week for main job	0.4	0.5	1.0	-1.0	0.0
Birth weight	0.4	0.9	1.5	0.6	1.2
Leg fat percentage (right)	0.4	1.4	1.7	-1.3	-1.0
Exposure to tobacco smoke outside home	0.4	0.5	0.7	-0.6	-0.9
Number of full brothers	0.4	0.6	1.1	-1.1	-0.0
Qualifications: College or University degree	0.4	1.1	2.0	0.5	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	0.7	0.4	0.8
Eye problems/disorders: Cataract	0.4	0.4	0.7	0.3	0.9
Osteoporosis (self-reported)	0.4	0.5	1.0	-0.2	1.0
Mother’s age at death	0.4	0.5	0.7	-0.6	-0.9
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.9	0.9	0.4
Medication: Atorvastatin	0.4	0.5	0.8	-0.9	-0.4
Commuting to job workplace: Cycle	0.4	0.5	0.6	0.6	-0.8
Heart disease (siblings)	0.4	0.5	0.8	-0.9	-0.4
Impedance of whole body	0.4	2.2	3.1	1.1	1.8
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.4	0.7	1.2
Schizophrenia vs Biploar Disorder	0.3	0.4	0.7	0.3	-0.8
Irritable Bowel Disease (IBD)	0.3	0.6	0.9	-1.0	-0.6
Ulcerative Colitis (UC)	0.3	0.6	1.1	-1.0	-0.4
Major Depression (MDD)	0.3	0.4	0.6	-0.4	-0.8
Reaction Time	0.3	0.5	0.9	1.0	0.3
Fasting Glucose	0.3	0.4	0.4	0.7	0.6
HbA1C	0.3	0.3	0.7	-0.1	-0.8
Lung FVC	0.3	1.5	3.0	-0.1	-1.7
Vitamin and mineral supplements	0.3	0.4	0.7	0.8	0.1
Diabetes (mother)	0.3	0.4	0.7	0.2	0.8
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.6	-0.3	0.7
Supplements: Glucosamine	0.3	0.4	0.9	-0.2	-0.9
Chronic bronchitis/emphysema (father)	0.3	0.3	0.6	-0.8	-0.3
Alcohol intake versus 10 years previously	0.3	0.5	0.5	-0.7	-0.7
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	1.2	-0.9	-1.1
Happiness	0.3	0.4	0.7	-0.3	-0.8
Noisy workplace	0.3	0.4	0.5	-0.7	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.6	-0.6	-1.2
Standing height	0.3	3.4	5.9	-2.4	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	0.3	-0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.8	0.1	-0.9
Headache pain in last month	0.3	0.5	1.0	-0.1	-1.0
Eye problems/disorders: None of the above	0.3	0.4	0.7	0.8	-0.1
Medication: Allopurinol	0.3	0.4	0.6	0.5	0.7
Number of full sisters	0.3	0.4	0.7	-0.2	-0.8
Illnesses of siblings: Diabetes	0.3	0.4	0.7	-0.8	-0.3
Ever taken oral contraceptive pill	0.3	0.3	0.4	0.4	-0.7
Commuting to job workplace: Public transport	0.3	0.4	0.7	-0.1	0.8
Number of operations (self-reported)	0.3	0.4	0.8	-0.9	-0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.6	0.8	-0.1
Vascular/heart problems diagnosed by doctor	0.3	0.8	1.3	0.5	-1.1
Supplements: Calcium	0.3	0.4	0.7	0.2	0.8
Lupus	0.2	0.3	0.7	-0.0	0.8
Schizophrenia (2014)	0.2	0.5	0.7	0.8	-0.6
Height	0.2	3.3	6.6	-2.6	-0.2
Chronotype (morning person)	0.2	0.5	0.7	-0.8	-0.6
Hair Pigment	0.2	5.9	9.2	-3.0	-1.6
Tanning	0.2	2.2	2.6	1.4	1.6
Average weekly spirits intake	0.2	0.3	0.5	0.2	0.7
Supplements: Zinc	0.2	0.2	0.3	-0.6	-0.1
Fed-up feelings	0.2	0.3	0.7	-0.0	0.8
Age when periods started (menarche)	0.2	0.5	0.8	0.4	-0.9
Nervous feelings	0.2	0.3	0.5	-0.7	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.6	-0.8	0.3
Had menopause	0.2	0.2	0.3	-0.3	0.6
Neuroticism score	0.2	0.5	0.7	-0.8	0.5
Falls in the last year	0.2	0.2	0.4	-0.6	0.2
Exposure to tobacco smoke at home	0.2	0.2	0.3	-0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.5	0.0	0.7
Hair/balding pattern: Pattern 4	0.2	0.4	0.5	-0.6	-0.7
Peak expiratory flow (PEF)	0.2	0.5	1.0	-1.0	0.2
Neck or shoulder pain in last month	0.2	0.3	0.4	-0.6	-0.4
Comparative height size at age 10	0.2	1.0	1.8	-1.4	0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	0.6	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	0.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.0	0.0	1.0
Loneliness, isolation	0.2	0.2	0.3	-0.5	0.4
Ever had bowel cancer screening	0.2	0.2	0.4	-0.0	0.6
Medication for cholesterol	0.2	0.2	0.4	0.3	0.6
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.6	-0.2
Financial situation satisfaction	0.2	0.3	0.4	0.5	0.6
Medication: Blood pressure	0.2	0.5	0.8	-0.9	-0.4
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	0.5	0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.3	-0.5	0.5
Crohns Disease (2012)	0.1	0.1	0.3	-0.1	0.5
Waist Hip Ratio (WHR)	0.1	0.4	0.7	0.2	0.9
Sensitivity / hurt feelings	0.1	0.2	0.2	-0.4	0.4
Relative age of first facial hair	0.1	0.3	0.4	-0.6	-0.4
Pack years adult smoking proportion	0.1	0.1	0.1	-0.3	0.2
Current tobacco smoking	0.1	0.2	0.3	0.3	0.5
Qualifications: CSEs or equivalent	0.1	0.2	0.2	-0.5	-0.3
High blood pressure	0.1	0.1	0.2	-0.3	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.3	0.1	0.6
Sitting height	0.1	1.0	1.2	-0.9	-1.1
Medication: Ramipril	0.1	0.1	0.2	0.4	-0.0
Illnesses of siblings	0.1	0.2	0.3	0.6	0.1
Impedance of arm (right)	0.1	0.5	0.9	-0.2	1.0
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.6	0.8	0.1
Impedance of arm (left)	0.1	0.3	0.4	-0.4	0.7
Medication: Amlodipine	0.1	0.2	0.2	-0.4	0.4
Forced vital capacity (FVC), Best measure	0.1	0.2	0.4	0.7	-0.1
Health satisfaction	0.1	0.1	0.1	-0.4	-0.2
Emphysema/chronic bronchitis	0.1	0.1	0.3	0.5	-0.2
Mean time to correctly identify matches	0.1	0.2	0.4	-0.1	-0.6
Hypertension (Self-reported)	0.1	0.4	0.7	-0.4	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.5	0.7	-0.2
Miserableness	0.1	0.2	0.3	-0.5	0.3
Hearing aid user	0.1	0.1	0.3	0.1	0.5
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.2	0.3	0.5
High cholesterol (Self-reported)	0.1	0.2	0.3	0.4	-0.5
Illnesses of father: High blood pressure	0.1	0.1	0.2	-0.4	0.2
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.1	-0.4
Cholesterol lowering medication	0.1	0.1	0.2	-0.5	-0.2
Basal cell carcinoma (self-reported)	0.1	0.2	0.2	0.3	0.5
Pack years of smoking	0.1	0.2	0.4	-0.6	0.2
Crohns Disease (2017)	0.0	0.0	0.0	-0.2	-0.1
LDL Cholesterol	0.0	0.1	0.1	-0.1	0.3
Cardiovascular Disease	0.0	0.0	0.1	0.2	0.2
Forced vital capacity (FVC)	0.0	0.1	0.2	0.0	0.4
Hair/balding pattern: Pattern 3	0.0	0.1	0.1	-0.1	-0.3
Pulse wave reflection index	0.0	0.0	0.0	0.2	-0.1
High blood pressure (siblings)	0.0	0.1	0.1	-0.4	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	-0.3	-0.0
Mineral and other dietary supplements	0.0	0.0	0.1	-0.2	0.0
Smoking status: Current	0.0	0.0	0.0	0.1	0.1
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.1	0.1	0.2
Medication: Bendroflumethiazide	0.0	0.1	0.1	0.0	-0.3
Medication: Lisinopril	0.0	0.0	0.0	-0.2	0.1

Hub : Genes

TLR10

Models

Trait associations