TWAS hub - THAP9-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0820	0.0350	3.8e-03	0.054	NA	0.029	NA	0.044	3.3e-05	NA	1.8e-03	NA	1.7e-04
2	GTEx	Adipose Visceral Omentum	0.1340	0.0440	1.7e-04	0.124	NA	0.082	NA	0.094	5.6e-07	NA	5.0e-05	NA	1.4e-05
3	GTEx	Adrenal Gland	0.1979	0.0760	2.1e-03	0.070	NA	0.033	NA	0.037	1.6e-03	NA	2.3e-02	NA	1.8e-02
4	GTEx	Artery Aorta	0.1910	0.0560	1.2e-05	0.139	NA	0.169	NA	0.168	4.3e-08	NA	1.3e-09	NA	1.5e-09
5	GTEx	Artery Tibial	0.2507	0.0494	1.4e-14	0.247	NA	0.231	NA	0.244	2.3e-19	NA	4.7e-18	NA	4.2e-19
6	GTEx	Brain Caudate basal ganglia	0.3230	0.1200	1.8e-03	0.006	NA	0.001	NA	0.034	2.1e-01	NA	3.0e-01	NA	3.7e-02
7	GTEx	Brain Cerebellar Hemisphere	0.1770	0.0690	5.2e-03	0.129	NA	0.041	NA	0.082	3.5e-04	NA	3.3e-02	NA	4.0e-03
8	GTEx	Brain Cerebellum	0.4080	0.1190	1.6e-04	0.108	NA	0.108	NA	0.070	4.4e-04	NA	4.3e-04	NA	4.2e-03
9	GTEx	Brain Cortex	0.2350	0.0950	4.2e-03	0.038	NA	-0.004	NA	0.058	3.3e-02	NA	4.3e-01	NA	1.1e-02
10	GTEx	Brain Frontal Cortex BA9	0.1848	0.0746	4.5e-03	0.134	NA	0.091	NA	0.133	2.1e-04	NA	2.1e-03	NA	2.3e-04
11	GTEx	Brain Hippocampus	0.3085	0.1058	1.9e-03	0.150	NA	0.091	NA	0.102	2.3e-04	NA	3.9e-03	NA	2.3e-03
12	GTEx	Breast Mammary Tissue	0.1600	0.0590	6.3e-04	0.125	NA	0.093	NA	0.111	6.1e-07	NA	1.7e-05	NA	2.7e-06
13	GTEx	Breast Mammary Tissue (Male)	0.0387	0.0726	3.4e-01	-0.004	NA	0.001	NA	0.069	4.0e-01	NA	3.1e-01	NA	1.1e-02
14	GTEx	Breast Mammary Tissue (Female)	0.0725	0.0521	1.1e-01	0.075	NA	0.007	NA	0.020	3.0e-03	NA	1.9e-01	NA	8.3e-02
15	GTEx	Cells EBV-transformed lymphocytes	0.1390	0.0660	7.6e-03	0.102	NA	0.117	NA	0.125	3.3e-04	NA	1.2e-04	NA	7.0e-05
16	GTEx	Cells Transformed fibroblasts	0.3250	0.0510	0.0e+00	0.374	NA	0.353	NA	0.363	1.9e-29	NA	1.9e-27	NA	2.1e-28
17	GTEx	Colon Transverse	0.1360	0.0550	3.6e-03	0.020	NA	0.036	NA	0.048	3.8e-02	NA	7.8e-03	NA	2.6e-03
18	GTEx	Heart Left Ventricle	0.1055	0.0471	8.5e-03	-0.003	NA	0.015	NA	-0.003	5.0e-01	NA	5.3e-02	NA	4.9e-01
19	GTEx	Lung	0.0677	0.0312	4.6e-03	0.047	NA	0.024	NA	0.026	1.7e-04	NA	5.3e-03	NA	3.9e-03
20	GTEx	Muscle Skeletal	0.1074	0.0274	1.7e-08	0.124	NA	0.108	NA	0.117	3.3e-12	NA	9.7e-11	NA	1.4e-11
21	GTEx	Nerve Tibial	0.0845	0.0351	3.2e-03	0.005	NA	0.011	NA	0.010	1.3e-01	NA	5.3e-02	NA	6.4e-02
22	GTEx	Pancreas	0.1700	0.0660	3.9e-03	0.001	NA	0.012	NA	0.001	2.8e-01	NA	1.0e-01	NA	2.9e-01
23	GTEx	Testis	0.2060	0.0560	7.0e-06	0.121	NA	0.165	NA	0.140	5.1e-06	NA	8.8e-08	NA	8.9e-07
24	GTEx	Thyroid	0.0560	0.0280	9.8e-03	0.007	NA	0.004	NA	0.001	8.3e-02	NA	1.5e-01	NA	2.4e-01
25	ROSMAP	Brain Pre-frontal Cortex	0.2413	0.0373	0.0e+00	0.288	0.299	0.313	0.333	0.321	3.2e-37	7.5e-39	6.1e-41	3.8e-44	3.5e-42

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	23	24	25
Seen a psychiatrist for nerves, anxiety, tension or depression	6.7	8.7	13.2	3.2	3.4	3.4	3.6	3.0	-0.4	2.1	2.4	3.6	3.2	3.2	2.6	2.8	2.4	3.1	3.3	3.6	1.5	3.4	3.2	3.0	3.4	2.3	3.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	6.5	7.6	15.1	3.5	3.4	3.4	2.4	3.3	1.1	2.7	1.1	3.2	3.4	3.4	-0.2	1.2	-0.7	3.9	3.4	2.8	0.5	3.6	3.4	1.9	3.1	3.5	2.8
Tense / ‘highly strung’	6.1	10.1	23.1	3.9	3.7	3.7	3.2	3.8	1.1	2.7	1.7	3.9	3.8	3.8	-0.4	1.4	-1.1	4.3	3.8	4.8	1.0	3.8	3.9	2.6	3.0	3.9	3.3
Cardiovascular Disease	4.9	16.3	27.5	5.0	4.7	4.7	4.6	5.0	0.2	3.6	2.4	4.9	5.0	5.0	0.3	3.1	-0.4	5.2	5.0	4.0	2.0	4.9	5.0	3.5	4.1	4.8	4.2
High blood pressure	4.6	12.8	21.0	4.4	4.2	4.1	4.2	4.3	0.6	2.9	2.4	4.6	4.3	4.3	1.1	2.3	0.7	4.3	4.4	3.6	0.9	4.3	4.4	3.5	4.0	3.8	4.2
Hypertension (Self-reported)	4.6	12.9	21.4	4.3	4.2	4.1	4.3	4.3	0.8	3.0	2.5	4.6	4.3	4.3	1.5	2.2	1.0	4.2	4.4	3.6	1.0	4.3	4.3	3.7	4.0	3.7	4.3
Vascular/heart problems diagnosed by doctor	4.5	12.4	19.9	-4.3	-4.1	-4.0	-4.0	-4.3	-0.8	-2.9	-2.2	-4.4	-4.4	-4.2	-0.5	-2.1	0.0	-4.5	-4.3	-3.5	-1.0	-4.3	-4.3	-3.4	-3.7	-4.2	-3.9
Average weekly spirits intake	4.2	5.2	8.8	-2.6	-2.7	-2.4	-2.3	-2.5	0.6	-1.5	-1.3	-2.6	-2.7	-3.0	-0.6	-2.5	-0.1	-2.6	-2.8	-3.0	0.9	-2.9	-2.7	-2.3	-2.4	-2.6	-2.7
Neuroticism score	4.2	8.7	15.1	3.5	3.4	3.6	3.3	3.6	2.3	3.7	1.9	3.4	3.5	3.2	-0.1	-0.1	-0.6	3.9	3.4	3.9	0.2	3.5	3.5	2.5	2.8	3.8	2.7
Handedness (chirality/laterality): Left-handed	4.2	5.1	9.7	2.6	2.7	2.5	3.0	2.6	1.1	2.5	-0.1	2.8	2.6	2.6	0.9	0.7	0.4	2.6	2.6	2.2	1.9	2.8	2.6	1.9	3.1	2.3	2.3
Worry (Nagel 2018)	4.1	8.7	14.7	3.7	3.5	3.6	3.1	3.8	1.2	2.7	1.8	3.5	3.7	3.1	0.3	1.3	-0.3	3.8	3.7	3.1	0.9	3.6	3.7	3.0	2.6	3.7	3.2
HDL Cholesterol	4.0	6.6	9.2	3.0	3.0	2.9	2.8	3.0	1.2	3.0	3.0	2.8	3.0	3.0	1.2	1.0	0.9	2.8	3.0	2.9	1.4	3.0	3.0	2.7	2.7	2.7	2.5
Blood Eosinophil Count	3.8	29.2	51.6	-6.1	-6.6	-6.0	-5.8	-6.0	-1.0	-5.5	-0.4	-6.4	-6.1	-5.1	-6.1	-3.2	-5.4	-5.2	-6.2	-6.2	-2.9	-6.1	-6.1	-7.2	-6.2	-3.6	-6.5
Blood White Count	3.7	27.1	44.2	-6.0	-6.4	-6.0	-5.5	-5.7	-1.1	-4.9	0.1	-6.1	-6.0	-5.4	-5.7	-3.1	-4.9	-5.0	-6.1	-5.2	-3.0	-6.0	-6.0	-6.7	-6.0	-3.7	-6.5
Suffer from ‘nerves’	3.5	5.5	8.7	2.8	2.8	2.8	2.8	2.9	2.5	2.8	1.3	2.8	2.7	2.5	1.0	-0.6	0.6	2.8	2.7	2.3	0.6	2.8	2.8	2.0	2.4	2.6	2.4
Ovarian Cancer	3.4	4.5	9.3	-2.3	-2.1	-2.1	-2.8	-2.6	-2.6	-3.0	-3.0	-2.2	-2.4	-1.9	0.5	1.2	0.8	-2.7	-2.2	-1.7	0.8	-2.2	-2.4	-0.8	-2.4	-2.8	-1.1
Systolic Blood Pressure	3.4	17.1	30.7	4.9	5.0	4.7	3.8	4.6	0.5	3.0	1.9	5.1	4.8	4.8	3.2	3.2	2.7	4.4	5.0	3.3	3.7	4.9	4.9	4.9	4.9	3.8	5.5
Medication: Amlodipine	3.4	4.7	6.8	2.5	2.5	2.5	2.6	2.5	2.2	2.2	2.5	2.4	2.4	2.6	1.4	-0.5	1.2	2.4	2.4	2.1	-0.5	2.5	2.5	2.5	2.3	1.9	2.2
Supplements: Glucosamine	3.2	4.2	8.4	2.1	2.3	2.1	1.4	2.2	1.1	1.6	2.1	2.3	2.1	1.9	2.9	0.6	2.7	1.5	2.1	2.6	1.5	2.1	2.1	2.6	2.7	0.9	2.6
Supplements: Fish oil (including cod liver oil)	3.2	4.2	10.6	2.0	2.2	2.1	1.8	2.0	-0.7	1.4	1.8	2.2	2.0	2.2	2.1	2.3	1.9	1.7	2.1	2.4	3.2	2.2	2.0	2.2	2.4	1.4	2.4
Worrier / anxious feelings	3.0	5.8	10.1	2.9	2.8	2.9	3.2	3.0	1.3	2.8	1.5	2.7	2.9	2.7	-0.1	0.6	-0.5	3.1	2.9	2.6	0.1	2.9	2.9	2.0	1.9	3.2	2.3
Frequency of tenseness / restlessness in last 2 weeks	2.9	4.5	8.0	2.6	2.5	2.5	2.3	2.7	1.4	2.8	1.2	2.4	2.6	2.4	-0.0	0.3	-0.4	2.8	2.5	2.4	0.4	2.5	2.6	1.5	2.4	2.6	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.3	8.7	2.3	2.3	2.2	2.8	2.4	0.4	2.0	1.8	2.5	2.3	2.2	-0.6	1.1	-0.8	2.8	2.3	3.0	1.7	2.5	2.3	1.0	2.2	2.5	1.6
Mineral and other dietary supplements	2.8	3.8	7.0	-2.1	-2.1	-2.3	-1.6	-2.1	0.5	-1.4	-1.6	-2.3	-2.1	-2.3	-1.2	-2.0	-0.9	-2.0	-2.2	-2.4	-2.6	-2.2	-2.1	-1.6	-2.6	-1.5	-2.4
Medication: Lisinopril	2.8	3.6	6.5	2.3	2.0	2.0	1.1	1.9	-1.0	1.4	2.4	2.3	2.2	2.1	-0.7	2.5	-1.1	2.4	2.3	1.9	-1.3	2.1	2.2	1.1	2.0	2.5	1.9
Loneliness, isolation	2.7	3.7	8.8	2.3	2.1	2.4	2.2	2.2	1.4	1.8	1.1	2.2	2.2	2.3	-0.8	-0.0	-1.0	3.0	2.2	2.2	-1.5	2.4	2.3	1.3	1.2	2.5	1.4
Fractured/broken bones in last 5 years	2.7	3.4	5.9	-2.3	-2.2	-1.9	-2.4	-2.2	0.5	-1.4	-1.2	-2.0	-2.3	-2.3	-0.6	-2.1	-0.4	-2.3	-2.4	-0.7	-0.1	-2.1	-2.3	-2.1	-2.0	-1.8	-2.2
Ulcerative Colitis	2.6	3.7	8.6	2.1	2.2	2.1	2.0	2.3	2.2	2.7	1.9	2.1	2.2	2.2	1.5	-0.6	1.1	1.9	2.1	1.0	0.7	2.2	2.1	1.7	2.9	1.7	1.9
Lung FEV1/FVC ratio	2.6	13.4	23.9	-4.5	-4.4	-4.7	-3.5	-4.5	-0.8	-3.6	-2.2	-4.2	-4.6	-4.5	-0.2	-2.2	0.4	-4.9	-4.6	-4.1	-0.5	-4.6	-4.6	-3.1	-3.3	-4.2	-3.7
Number of live births	2.6	3.6	6.3	2.3	2.3	2.2	2.0	2.2	-0.7	1.8	0.4	2.0	2.2	2.1	0.9	2.3	0.6	2.3	2.3	1.7	0.7	2.3	2.3	2.0	1.9	2.5	2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.6	5.5	10.6	-2.8	-2.7	-3.2	-3.0	-2.9	-1.7	-3.0	-0.5	-2.2	-2.8	-3.1	0.3	-0.1	0.6	-3.2	-2.8	-1.3	-0.8	-2.9	-2.9	-1.9	-2.0	-3.2	-1.8
Irritable Bowel Disease (IBD)	2.5	6.0	14.1	2.7	2.8	2.6	2.3	2.9	1.3	3.2	2.2	2.8	2.8	2.8	1.9	0.6	1.5	2.3	2.7	2.4	2.0	2.7	2.8	2.4	3.8	2.2	2.5
Peak expiratory flow (PEF)	2.4	5.5	10.1	-2.9	-2.7	-2.9	-3.2	-2.9	-1.2	-2.2	-1.5	-2.5	-2.9	-2.6	0.3	-0.7	0.8	-3.1	-2.9	-2.4	0.3	-2.8	-2.9	-1.9	-2.6	-2.9	-2.3
Schizophrenia (2018)	2.3	4.8	7.7	2.6	2.5	2.6	1.8	2.5	1.1	2.1	2.6	2.3	2.7	2.4	0.9	0.7	0.6	2.6	2.7	2.6	0.4	2.6	2.7	1.7	2.8	2.5	2.7
Chronic bronchitis/emphysema (father)	2.3	2.7	7.6	2.0	2.0	1.9	1.5	2.1	0.7	1.8	-0.1	1.8	1.9	2.0	-0.1	0.7	-0.5	2.2	2.0	1.4	1.5	2.0	2.0	1.4	1.7	2.7	1.4
Medication: Gliclazide	2.3	2.6	6.1	-1.7	-1.7	-1.8	-1.9	-1.7	-1.4	-1.9	-2.5	-1.9	-1.7	-1.6	-0.7	0.1	-0.4	-1.5	-1.7	-2.4	-1.5	-1.6	-1.7	-1.5	-1.4	-1.7	-1.6
Hearing aid user	2.3	2.6	4.8	-1.8	-1.9	-2.1	-1.9	-1.9	-0.3	-1.6	-2.2	-1.9	-1.8	-1.8	-0.7	-1.0	-0.4	-1.9	-1.8	-1.7	-0.2	-1.9	-1.8	-1.2	-2.1	-1.6	-1.6
High blood pressure (mother)	2.2	3.1	6.4	1.8	1.9	1.7	2.5	1.7	0.9	1.4	2.2	2.1	1.7	1.9	2.2	0.6	2.1	1.3	1.8	1.8	1.6	1.7	1.8	2.1	1.6	0.9	2.2
Loud music exposure frequency	2.2	2.4	5.5	1.8	1.7	2.1	2.3	1.8	2.0	2.2	0.8	1.5	1.8	1.7	-0.4	-0.9	-0.5	2.0	1.7	1.1	-0.3	1.8	1.8	1.0	1.4	1.8	0.7
Medication: Allopurinol	2.2	3.0	6.2	-2.1	-2.0	-2.0	-1.8	-2.2	-1.2	-2.0	-1.6	-2.2	-2.0	-1.7	-0.5	-0.2	-0.2	-2.1	-2.0	-2.5	-0.2	-2.0	-2.0	-1.2	-1.9	-2.0	-1.4
Guilty feelings	2.2	3.3	6.9	2.0	2.0	2.0	1.7	2.2	1.5	2.1	0.6	1.9	2.0	2.1	1.1	-0.1	0.9	2.0	2.0	2.6	2.3	2.1	2.0	2.1	1.4	1.7	1.7
Ulcerative Colitis (UC)	2.0	3.7	9.3	2.1	2.2	2.2	1.7	2.1	0.9	2.4	1.8	2.2	2.2	2.4	1.8	0.7	1.5	1.8	2.0	1.9	1.7	2.1	2.1	1.8	3.1	1.5	1.9
Major Depression (MDD)	2.0	2.4	4.5	1.8	1.6	1.7	1.7	1.9	0.2	1.2	1.9	1.4	1.8	1.9	-0.8	0.9	-1.1	2.1	1.9	2.0	1.3	1.8	1.9	0.6	1.7	1.9	1.3
Breast Cancer	2.0	4.9	11.9	2.7	2.2	2.8	2.9	2.5	0.3	1.9	0.6	2.1	2.7	2.7	-1.2	1.3	-1.7	3.2	2.7	1.5	-2.1	2.5	2.6	1.0	2.1	3.5	1.8
Schizophrenia (2014)	2.0	4.4	7.6	2.5	2.4	2.5	1.8	2.4	1.2	2.4	2.4	2.1	2.5	2.4	0.8	0.4	0.5	2.6	2.5	2.8	0.9	2.5	2.5	1.6	2.5	2.3	2.2
Worry too long after embarrassment	2.0	3.3	6.9	2.1	2.0	2.1	1.3	2.2	1.9	2.6	1.3	2.1	2.0	2.0	0.1	-0.6	-0.2	2.4	2.0	1.8	-0.5	2.1	2.1	1.7	2.0	2.4	1.7
Bipolar Disorder or Schizophrenia	1.9	4.5	8.8	2.4	2.4	2.5	1.7	2.2	-0.1	1.6	2.7	2.4	2.5	2.4	0.0	1.8	-0.3	2.7	2.5	3.0	0.9	2.5	2.5	1.2	2.6	2.8	2.3
Fasting Glucose	1.9	2.2	3.8	1.0	1.7	1.8	1.6	1.6	0.4	1.0	2.0	1.9	1.7	1.7	1.7	0.9	1.7	1.4	1.7	1.6	-0.7	1.7	1.7	1.7	1.6	1.1	1.9
Chronotype (morning person)	1.9	4.4	9.6	-2.4	-2.4	-2.5	-3.1	-2.3	0.3	-1.0	-0.0	-2.1	-2.4	-2.3	-1.7	-2.2	-1.4	-2.1	-2.4	-1.8	-2.3	-2.4	-2.4	-2.4	-2.4	-1.7	-2.6
Father’s age at death	1.9	2.6	10.2	1.5	1.6	1.5	1.3	1.4	-0.3	0.8	1.3	1.6	1.5	1.5	2.1	1.5	1.9	1.2	1.6	1.2	3.2	1.5	1.5	1.9	2.4	0.6	2.1
Smoking status: Current	1.9	3.1	6.5	2.1	1.9	1.9	2.3	2.3	1.2	2.1	1.4	1.6	2.1	2.0	-0.7	0.2	-1.1	2.4	2.1	2.5	0.6	1.9	2.1	1.0	1.1	2.4	1.0
Crohns Disease (2017)	1.8	3.8	7.9	2.2	2.3	2.0	1.9	2.4	1.5	2.3	1.5	2.3	2.3	2.1	1.0	0.0	0.6	1.9	2.3	2.1	1.1	2.2	2.4	2.0	2.8	2.1	2.2
Bipolar Disorder (2011)	1.8	1.7	3.7	1.4	1.4	1.5	1.3	1.3	0.7	1.1	1.5	1.7	1.4	1.6	1.1	0.4	0.9	1.4	1.4	1.5	0.9	1.5	1.4	1.2	1.9	1.3	1.4
Systolic blood pressure, automated reading	1.8	5.3	11.4	2.6	2.6	2.4	2.2	2.4	-0.0	1.3	1.3	3.0	2.5	2.5	2.5	2.0	2.2	2.0	2.7	1.6	2.4	2.5	2.6	3.2	2.6	1.3	3.4
Supplements: Vitamin C	1.8	2.1	6.1	1.4	1.4	1.5	2.0	1.5	1.3	1.9	2.5	1.8	1.4	1.5	1.2	-0.4	1.1	1.2	1.4	2.0	0.1	1.4	1.4	1.7	1.4	0.9	1.5
Supplements: Calcium	1.8	2.0	5.6	1.6	1.5	1.6	0.7	1.6	0.6	0.8	2.4	1.6	1.6	1.9	0.3	0.5	0.1	1.5	1.6	2.0	-1.2	1.5	1.6	0.9	1.9	1.4	1.8
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	9.2	-1.2	-1.4	-1.5	-1.8	-1.4	-1.2	-1.6	-2.7	-1.2	-1.2	-1.2	-3.0	0.0	-3.0	-0.6	-1.2	-0.4	-0.5	-1.1	-1.2	-1.8	-1.3	0.3	-1.6
Verbal and Numeric Reasoning (VNR)	1.7	4.1	7.0	-2.2	-2.1	-2.5	-2.3	-2.2	0.6	-1.5	-2.6	-2.2	-2.3	-1.8	0.7	-2.1	1.1	-2.7	-2.3	-2.4	1.4	-2.3	-2.3	-1.1	-2.3	-2.6	-1.7
Neuroticism	1.7	4.1	8.7	2.5	2.3	2.4	2.2	2.4	1.0	2.2	0.9	2.2	2.5	2.0	-0.8	0.5	-1.3	2.9	2.4	2.7	0.2	2.4	2.5	1.5	1.5	3.0	1.8
Current tobacco smoking	1.7	2.8	6.4	2.0	1.7	1.8	2.2	2.2	1.5	2.2	1.1	1.4	2.0	1.8	-1.2	-0.3	-1.6	2.3	1.9	2.1	0.3	1.8	2.0	0.7	0.9	2.5	0.6
Waist circumference	1.7	6.1	10.4	-2.9	-3.0	-3.0	-2.4	-2.9	-0.3	-2.3	-1.4	-2.9	-2.9	-2.7	-1.3	-1.9	-0.8	-2.7	-3.0	-3.1	-0.9	-3.0	-2.9	-2.3	-3.2	-2.3	-3.0
Nervous feelings	1.7	3.1	5.8	2.1	1.9	2.0	2.0	2.3	1.0	1.8	1.0	2.1	2.1	2.0	-0.1	0.4	-0.4	2.2	2.1	2.3	-1.0	2.0	2.1	1.3	1.8	2.4	1.7
Neck or shoulder pain in last month	1.7	2.4	5.4	1.6	1.7	1.8	2.2	1.6	2.3	2.1	1.0	1.4	1.6	1.9	0.0	-1.3	-0.0	2.0	1.5	1.3	1.5	2.0	1.6	1.3	0.9	1.9	0.7
Ever had bowel cancer screening	1.7	2.0	5.2	1.7	1.6	1.4	2.3	1.8	0.4	1.2	1.0	1.7	1.7	1.4	0.0	0.7	-0.4	1.6	1.7	1.0	-0.5	1.6	1.6	1.2	2.1	1.5	1.6
Neuroticism (Nagel 2018)	1.6	3.7	6.8	2.3	2.3	2.4	2.2	2.4	1.2	1.9	0.6	2.3	2.3	2.1	0.4	0.3	0.0	2.6	2.3	2.2	0.4	2.5	2.4	2.0	1.5	2.4	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	8.9	-2.7	-2.6	-2.8	-2.8	-2.8	0.2	-1.5	-1.5	-2.5	-2.7	-2.8	0.2	-2.0	0.6	-3.0	-2.7	-2.2	-0.5	-2.8	-2.7	-1.8	-2.5	-2.5	-2.4
Blood clot in the leg (DVT)	1.6	2.1	9.7	-1.1	-1.2	-1.4	-1.7	-1.2	-1.0	-1.5	-2.6	-1.1	-1.0	-1.0	-3.1	-0.1	-3.1	-0.5	-1.1	-0.4	-0.5	-1.0	-1.1	-1.7	-1.3	0.5	-1.4
Eye problems/disorders: Cataract	1.6	1.8	3.7	-1.6	-1.6	-1.6	-1.0	-1.5	-1.3	-1.9	-1.1	-1.4	-1.5	-1.6	-0.8	0.2	-0.6	-1.4	-1.5	-1.0	-1.7	-1.5	-1.5	-1.7	-1.2	-1.4	-1.1
Mean Putamen Volume	1.5	1.7	3.5	1.5	1.4	1.2	1.1	1.5	0.1	0.6	0.7	1.6	1.5	1.4	0.7	1.1	0.5	1.4	1.6	1.4	1.3	1.4	1.5	0.6	1.9	1.8	1.8
Lupus	1.5	2.3	4.7	1.8	1.8	1.8	1.6	2.0	0.7	2.1	0.6	1.3	2.0	1.5	0.0	0.6	-0.4	1.9	1.9	1.5	-0.5	1.8	1.9	1.5	1.2	2.2	1.5
Smoking Status	1.5	3.6	6.5	2.2	2.0	1.9	2.4	2.4	2.5	2.6	2.0	1.9	2.2	2.1	-0.8	-1.2	-1.0	2.5	2.0	2.0	0.6	2.1	2.2	1.0	1.2	2.3	1.1
Mood swings	1.5	2.7	5.0	2.0	2.0	2.2	2.0	2.0	1.7	2.2	-0.1	1.7	1.9	1.6	0.4	-0.5	0.2	2.2	1.9	1.6	1.0	2.1	2.0	1.7	1.4	1.9	1.2
Wears glasses or contact lenses	1.5	1.7	7.9	-1.2	-1.1	-1.4	-0.7	-1.4	-2.8	-2.1	-1.5	-0.6	-1.2	-1.4	0.9	2.1	1.2	-1.5	-1.1	-0.4	0.5	-1.2	-1.3	-0.3	-0.5	-1.7	-0.2
High cholesterol (Self-reported)	1.5	2.6	6.5	2.1	1.9	1.7	1.6	1.9	0.4	1.3	-0.6	2.0	2.1	2.0	-0.8	0.9	-1.1	2.4	2.1	1.2	0.1	2.0	2.1	1.1	1.3	2.5	1.7
Hearing difficulty/problems: Yes	1.4	2.2	4.6	-1.5	-1.6	-1.7	-1.4	-1.7	-0.8	-2.0	-2.1	-1.7	-1.5	-1.8	-1.4	-0.4	-1.4	-1.5	-1.5	-1.8	-0.7	-1.6	-1.5	-1.8	-1.6	-1.1	-1.3
Supplements: Zinc	1.4	1.6	3.4	1.4	1.4	1.5	1.4	1.4	1.1	1.1	1.0	1.4	1.4	1.7	0.8	-0.1	0.8	1.4	1.4	1.1	0.7	1.5	1.4	0.9	1.9	1.4	1.4
Trunk fat percentage	1.4	5.6	14.1	-2.6	-2.7	-2.7	-2.3	-2.8	-1.3	-2.6	-2.1	-2.5	-2.7	-2.3	-2.0	-0.7	-1.7	-2.2	-2.7	-3.3	-0.6	-2.5	-2.6	-2.1	-3.7	-1.7	-2.8
Trunk fat mass	1.4	6.1	14.3	-2.8	-2.9	-2.9	-2.2	-2.9	-0.7	-2.5	-2.3	-2.7	-2.8	-2.5	-1.9	-1.4	-1.5	-2.4	-2.9	-3.3	-0.9	-2.8	-2.8	-2.2	-3.8	-1.9	-3.0
Gout (self-reported)	1.4	1.9	6.4	-1.6	-1.4	-1.3	-0.8	-1.6	0.0	-1.4	-1.2	-1.4	-1.6	-1.4	1.0	-1.0	1.2	-1.9	-1.6	-2.5	0.6	-1.5	-1.6	-0.2	-1.3	-2.4	-0.6
Medication: Blood pressure	1.4	2.5	5.4	1.9	1.8	1.5	1.2	1.9	0.3	1.1	1.0	2.3	1.9	1.7	0.4	0.9	0.1	1.8	1.9	1.6	-0.8	1.8	1.9	1.6	1.9	2.3	2.1
Chest pain or discomfort	1.4	2.0	3.4	1.7	1.6	1.7	1.5	1.6	-0.5	0.9	1.2	1.5	1.7	1.5	0.0	1.8	-0.4	1.7	1.8	1.7	0.6	1.6	1.7	1.3	1.4	1.8	1.6
Illnesses of father: High blood pressure	1.4	1.8	4.2	1.6	1.6	1.2	1.5	1.6	0.7	1.0	1.1	1.6	1.6	1.1	1.4	0.5	1.1	1.0	1.6	1.0	-0.7	1.4	1.6	1.7	2.0	1.1	1.8
Heart disease (siblings)	1.4	1.7	3.8	-1.5	-1.4	-1.7	-1.5	-1.4	-0.6	-1.5	-1.1	-1.0	-1.5	-1.4	0.8	-0.3	1.0	-1.9	-1.5	-0.8	1.5	-1.5	-1.5	-0.5	-1.7	-1.7	-0.8
Alzheimer’s Disease (in mother)	1.3	1.5	4.1	-1.3	-1.3	-1.2	-0.8	-1.3	-1.2	-2.0	-1.1	-1.6	-1.3	-1.0	-1.8	0.1	-1.7	-0.7	-1.3	-1.5	-0.3	-1.1	-1.2	-1.9	-0.7	-0.2	-1.3
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	4.2	-1.3	-1.3	-1.4	-0.9	-1.3	-1.3	-2.1	-1.9	-1.6	-1.3	-1.2	-1.5	0.4	-1.4	-1.1	-1.3	-1.3	-0.9	-1.2	-1.2	-1.2	-1.4	-0.7	-1.3
Hip circumference	1.3	5.4	10.1	-2.7	-2.8	-2.8	-2.4	-2.6	-0.2	-2.0	-1.6	-2.7	-2.7	-2.5	-1.2	-1.8	-0.8	-2.4	-2.8	-3.1	-0.6	-2.8	-2.7	-2.4	-3.2	-2.3	-2.9
High blood pressure (siblings)	1.3	1.8	5.2	1.3	1.6	1.3	1.6	1.4	0.6	1.4	0.6	1.9	1.3	1.4	2.2	0.5	2.1	1.0	1.3	1.0	0.6	1.4	1.4	2.3	0.7	0.9	1.5
Medication: Bendroflumethiazide	1.3	1.9	3.5	1.7	1.6	1.6	1.6	1.7	1.4	1.7	0.2	1.9	1.7	1.5	0.8	-0.3	0.7	1.6	1.6	1.4	0.7	1.6	1.6	1.8	0.8	1.1	1.4
Irritability	1.3	2.1	5.5	1.6	1.6	1.6	1.9	1.6	1.3	1.7	-0.4	1.8	1.7	1.3	1.0	-0.3	0.8	1.7	1.6	2.4	0.6	1.6	1.7	1.1	2.0	1.2	1.5
Prostate Cancer	1.2	1.7	5.8	1.3	1.4	1.3	0.8	1.2	0.9	1.0	0.4	1.4	1.3	0.9	2.4	0.2	2.3	0.7	1.3	1.1	0.9	1.1	1.3	1.5	2.0	0.3	1.8
Blood Red Count	1.2	11.2	65.0	-2.1	-2.9	-2.1	-2.5	-2.1	-0.4	-1.4	-2.2	-2.4	-2.1	-2.3	-8.0	-2.1	-8.1	-0.4	-2.3	-2.2	-4.2	-2.2	-2.1	-5.6	-2.7	1.1	-4.2
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	6.2	-1.6	-1.8	-1.8	-1.8	-1.7	-1.4	-1.6	-0.7	-2.1	-1.6	-2.0	-1.3	0.1	-1.0	-1.6	-1.6	-1.5	-2.1	-1.7	-1.6	-1.4	-2.5	-0.7	-2.4
Multivitamins +/- minerals	1.2	1.5	8.1	1.2	1.2	1.2	0.9	1.1	-2.0	0.2	-0.9	1.1	1.1	1.4	0.7	2.8	0.4	1.2	1.3	0.5	1.4	1.3	1.2	1.0	1.5	0.9	1.3
Arm fat percentage (right)	1.2	4.7	11.2	-2.5	-2.6	-2.5	-2.1	-2.5	-0.7	-2.3	-1.7	-2.3	-2.5	-2.2	-1.6	-1.2	-1.3	-2.0	-2.5	-3.2	-0.1	-2.4	-2.5	-2.0	-3.3	-1.8	-2.5
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.7	1.4	1.3	1.7	1.4	1.4	0.2	1.3	1.0	0.9	1.4	1.4	-1.1	0.6	-1.3	1.9	1.4	0.4	-0.1	1.5	1.4	1.0	0.6	1.9	0.8
Body fat percentage	1.2	4.9	12.1	-2.4	-2.5	-2.5	-2.2	-2.6	-1.5	-2.6	-2.0	-2.3	-2.5	-2.2	-1.6	-0.4	-1.3	-2.1	-2.5	-3.2	-0.4	-2.4	-2.5	-1.8	-3.5	-1.8	-2.5
Medication for pain relief, constipation, heartburn	1.2	2.1	5.3	-1.6	-1.5	-1.7	-2.3	-1.6	-0.2	-1.0	-1.3	-1.5	-1.6	-1.5	1.2	-0.8	1.5	-2.0	-1.6	-1.2	1.0	-1.7	-1.7	-1.0	-0.7	-2.3	-1.3
Whole body fat mass	1.2	5.1	12.1	-2.5	-2.7	-2.6	-2.0	-2.6	-0.8	-2.3	-2.0	-2.5	-2.6	-2.3	-1.8	-1.1	-1.4	-2.1	-2.6	-3.1	-0.9	-2.5	-2.5	-2.1	-3.5	-1.9	-2.8
Arm fat percentage (left)	1.2	4.6	10.8	-2.5	-2.6	-2.5	-2.0	-2.5	-0.9	-2.3	-1.6	-2.3	-2.5	-2.2	-1.3	-1.0	-1.0	-2.1	-2.5	-3.2	-0.2	-2.4	-2.5	-1.9	-3.3	-2.0	-2.5
Alzheimer’s Disease (in father)	1.1	1.2	5.0	0.8	1.0	1.0	1.3	0.9	0.1	0.8	0.7	0.6	0.8	1.0	2.2	0.6	2.2	0.4	0.8	0.2	2.2	0.9	0.8	1.3	1.1	-0.4	1.3
Blood Platelet Count	1.1	12.2	55.7	2.8	3.4	2.5	1.9	2.7	0.9	2.2	1.4	3.4	2.8	2.7	7.5	1.8	7.3	1.2	2.9	3.4	4.6	2.8	2.8	5.4	4.1	0.5	4.2
Relative age of first facial hair	1.1	2.2	3.8	1.6	1.7	1.7	1.4	1.8	-0.7	1.2	1.0	1.8	1.6	1.8	0.8	1.9	0.6	1.7	1.7	1.1	1.2	1.7	1.7	1.4	1.9	1.2	1.9
Diabetes (father)	1.1	1.3	4.1	-1.1	-1.2	-0.7	-0.7	-1.0	0.6	-0.3	0.3	-1.1	-1.2	-0.7	-2.0	-1.6	-2.0	-0.5	-1.2	-1.2	-2.0	-0.9	-1.1	-1.3	-0.9	-0.1	-1.5
Past tobacco smoking	1.1	2.0	3.4	-1.8	-1.8	-1.6	-1.1	-1.8	-0.6	-1.6	-1.2	-1.8	-1.8	-1.6	-0.6	-0.7	-0.5	-1.6	-1.8	-1.0	-1.2	-1.8	-1.8	-1.2	-1.7	-1.1	-1.7
Financial difficulties in last 2 years	1.1	1.4	2.9	-1.2	-1.4	-1.1	-1.1	-1.2	-0.1	-1.4	-0.2	-1.7	-1.1	-0.8	-1.3	-0.8	-1.2	-1.0	-1.2	-1.5	-1.6	-1.4	-1.2	-1.7	-1.2	-1.1	-1.4
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	6.5	-2.3	-2.2	-2.4	-2.5	-2.4	-0.2	-1.4	-1.4	-2.0	-2.3	-2.3	0.1	-1.3	0.6	-2.5	-2.3	-1.9	-0.8	-2.4	-2.3	-1.5	-2.5	-2.3	-2.1
Arm fat mass (right)	1.1	4.7	10.1	-2.4	-2.6	-2.5	-1.9	-2.4	-0.0	-2.0	-1.7	-2.4	-2.5	-2.2	-1.5	-1.9	-1.2	-2.1	-2.5	-3.1	-0.5	-2.5	-2.5	-2.1	-3.2	-1.9	-2.7
Heart disease (mother)	1.1	1.4	3.7	-1.4	-1.3	-1.3	-0.5	-1.4	-0.8	-1.5	-1.8	-1.2	-1.4	-1.4	-0.0	-0.1	0.2	-1.4	-1.4	-1.0	-0.1	-1.3	-1.4	-0.6	-1.9	-1.5	-1.1
Medication: Aspirin	1.1	1.4	3.9	1.3	1.2	0.9	1.2	1.1	-1.1	-0.0	0.5	1.1	1.3	1.2	-0.6	2.0	-0.8	1.4	1.4	1.3	-1.3	1.3	1.3	0.9	1.1	2.0	1.3
Osteoporosis (self-reported)	1.1	1.4	3.8	1.0	1.2	1.0	0.6	1.0	0.2	0.9	1.1	1.4	1.0	1.3	1.8	0.7	1.7	0.7	1.1	2.0	0.5	1.0	1.0	1.5	1.7	1.2	1.5
Medication: Aspirin	1.1	1.5	4.4	1.4	1.3	1.0	1.3	1.2	-1.1	0.0	0.1	1.2	1.4	1.3	-0.0	2.1	-0.3	1.4	1.5	1.3	-0.5	1.3	1.4	1.3	1.1	1.7	1.7
Arm fat mass (left)	1.1	4.5	10.0	-2.4	-2.5	-2.5	-1.8	-2.3	-0.1	-1.9	-1.7	-2.3	-2.4	-2.1	-1.4	-1.8	-1.1	-2.0	-2.5	-3.1	-0.7	-2.4	-2.4	-1.9	-3.2	-1.9	-2.6
Average weekly champagne plus white wine intake	1.1	1.5	2.8	1.2	1.3	1.1	1.2	1.2	-0.2	0.9	1.6	1.4	1.2	1.0	1.7	1.2	1.6	1.0	1.3	1.3	1.0	1.1	1.3	1.6	1.2	1.0	1.7
Alcohol drinker status: Previous	1.1	1.3	2.3	-1.3	-1.3	-1.2	-1.2	-1.2	-1.2	-1.0	-1.0	-1.3	-1.2	-1.5	-0.8	0.2	-0.6	-1.0	-1.3	-0.6	-0.9	-1.2	-1.2	-1.5	-1.4	-0.8	-1.5
Schizophrenia vs Biploar Disorder	1.0	1.4	3.6	1.3	1.2	1.3	1.0	1.4	1.9	1.9	1.3	1.1	1.3	1.0	0.2	-1.1	0.1	1.5	1.2	0.9	-0.5	1.4	1.3	0.8	0.9	1.3	0.8
Severe depression (siblings)	1.0	1.1	3.5	1.1	1.1	1.1	0.2	1.1	0.1	1.0	1.9	1.2	1.1	1.0	0.7	0.8	0.4	0.9	1.1	1.0	1.6	1.1	1.1	1.1	0.9	1.1	1.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	2.6	1.2	1.3	1.2	1.2	1.1	-0.5	0.7	0.2	1.3	1.2	1.1	0.6	1.3	0.4	1.4	1.2	1.6	0.9	1.4	1.2	1.1	1.3	1.1	1.1
Happiness	1.0	1.2	3.0	1.2	1.1	1.2	1.7	1.2	0.6	1.3	0.9	1.1	1.1	1.1	-0.7	0.0	-0.7	1.6	1.1	1.5	0.9	1.2	1.2	0.2	0.9	1.5	0.7
Length of working week for main job	1.0	1.1	3.5	-1.1	-1.2	-1.1	-1.0	-1.1	-0.1	-0.9	-1.9	-1.2	-1.2	-0.8	-1.1	-0.8	-0.9	-0.9	-1.2	-0.9	-1.0	-1.0	-1.1	-0.8	-1.4	-0.7	-1.4
Leg fat mass (right)	1.0	3.9	8.4	-2.2	-2.3	-2.3	-1.8	-2.3	-0.7	-2.1	-1.7	-2.1	-2.2	-2.1	-1.6	-1.0	-1.3	-1.9	-2.2	-2.6	-0.9	-2.2	-2.2	-1.8	-2.9	-1.7	-2.3
Family relationship satisfaction	1.0	1.2	4.6	1.1	1.1	1.1	1.0	1.2	1.5	1.6	-0.1	0.9	1.1	1.1	0.5	-0.8	0.4	1.2	1.0	1.0	2.1	1.1	1.1	0.7	1.2	1.2	0.8
Leg pain on walking	1.0	1.2	3.0	1.1	1.2	1.0	0.8	1.0	0.4	0.4	0.7	1.4	1.1	0.8	1.4	0.5	1.4	0.9	1.2	1.7	1.0	1.1	1.1	1.3	1.4	0.8	1.5
Commuting to job workplace: Walk	1.0	1.1	3.0	-1.1	-1.2	-1.7	-1.5	-0.9	-0.4	-0.8	-1.4	-1.0	-1.2	-1.1	0.3	-0.3	0.7	-1.5	-1.1	-0.7	-0.1	-1.3	-1.2	-0.8	-1.2	-1.4	-0.9
HbA1C	0.9	1.0	2.3	-0.5	-1.1	-1.1	-1.5	-1.3	0.3	-0.5	0.7	-1.2	-1.2	-1.2	-0.4	-1.1	-0.2	-1.2	-1.4	-1.2	-0.2	-1.2	-1.4	-1.0	-0.8	-1.0	-1.2
Neuroticism (2016)	0.9	1.3	4.7	1.1	1.0	0.9	1.0	1.2	1.8	1.9	0.2	0.8	1.1	1.1	-1.0	-1.3	-1.1	1.6	1.0	0.7	0.5	1.2	1.2	0.5	1.0	2.2	0.4
Average weekly fortified wine intake	0.9	1.0	2.0	-1.1	-1.2	-1.3	-1.0	-1.1	-0.5	-1.2	-1.3	-1.2	-1.1	-0.9	-0.8	-0.3	-0.6	-0.9	-1.1	-0.8	-0.1	-1.1	-1.1	-1.4	-1.2	-0.5	-1.2
Medication: Simvastatin	0.9	1.3	3.2	1.4	1.4	1.2	1.5	1.4	0.7	1.2	-0.4	1.2	1.4	1.2	0.3	0.1	0.1	1.4	1.4	0.4	-0.1	1.3	1.4	1.3	1.0	1.8	1.4
Leg fat percentage (right)	0.9	3.2	7.1	-1.9	-2.0	-2.0	-1.8	-2.2	-1.8	-2.4	-1.7	-1.7	-2.0	-1.9	-1.2	0.4	-1.0	-1.7	-1.9	-2.5	-0.6	-1.9	-1.9	-1.4	-2.7	-1.6	-1.7
Breast cancer (self-reported)	0.9	1.1	3.2	-1.2	-1.0	-1.2	-0.9	-1.1	-0.6	-0.6	-1.0	-0.8	-1.2	-1.4	1.1	-0.0	1.3	-1.4	-1.1	-1.0	-1.5	-1.1	-1.2	-0.3	-0.3	-1.8	-0.7
Risk taking	0.9	1.4	2.9	1.3	1.3	1.4	1.1	1.3	1.3	1.6	0.9	1.3	1.3	1.4	-0.9	-0.6	-1.2	1.7	1.3	1.2	0.3	1.4	1.3	0.8	0.4	1.3	0.7
Ever depressed for a whole week	0.9	1.1	2.0	1.1	1.2	1.2	1.1	1.1	0.4	1.3	1.2	1.0	1.1	1.1	0.8	0.4	0.7	1.3	1.1	1.1	0.5	1.2	1.1	1.1	1.4	1.2	0.9
Heart attack/myocardial infarction (self-reported)	0.9	1.1	6.0	-0.1	-0.2	-0.3	0.1	-0.0	1.5	-0.1	0.4	-0.3	-0.1	0.1	-2.2	-1.8	-2.3	0.6	-0.2	0.0	-2.4	0.1	-0.1	-1.2	0.0	1.7	-0.8
Leg fat mass (left)	0.9	3.6	8.4	-2.1	-2.2	-2.1	-1.6	-2.2	-0.9	-2.1	-1.7	-2.1	-2.1	-2.0	-1.4	-0.7	-1.1	-1.8	-2.1	-2.6	-0.9	-2.1	-2.1	-1.6	-2.9	-1.6	-2.2
Medication for hormone replacement therapy	0.8	0.9	6.6	0.3	-0.0	0.2	0.7	-0.2	-0.5	-0.6	-1.2	0.1	0.2	0.4	-2.4	0.4	-2.6	1.0	0.2	0.0	-1.4	0.3	0.2	-0.7	-0.6	1.1	-0.6
Vitamin and mineral supplements	0.8	1.1	5.1	-0.9	-1.0	-1.1	-0.5	-0.9	1.5	-0.2	0.6	-1.2	-0.9	-1.2	-1.0	-2.3	-0.8	-0.8	-1.0	-0.8	-1.6	-1.0	-0.9	-1.1	-1.2	-0.3	-1.3
Maternal smoking around birth	0.8	1.1	6.6	-1.1	-1.1	-1.1	-0.3	-1.1	1.6	-0.8	-0.5	-1.0	-1.0	-0.9	-0.5	-2.6	-0.2	-0.8	-1.2	-0.6	0.8	-0.9	-1.1	-0.9	-1.3	-0.6	-1.5
Heart attack	0.8	1.0	4.4	0.4	0.2	0.1	0.5	0.4	1.5	0.1	0.3	0.1	0.4	0.7	-2.0	-1.5	-2.0	1.1	0.3	0.5	-2.1	0.6	0.4	-0.8	0.5	2.0	-0.3
Weight	0.8	3.7	8.0	-2.2	-2.3	-2.3	-1.5	-2.0	0.6	-1.4	-1.6	-2.2	-2.2	-2.0	-1.1	-2.3	-0.7	-1.9	-2.3	-2.5	-1.1	-2.2	-2.2	-1.7	-2.8	-1.8	-2.4
Smoking status: Previous	0.8	1.3	2.2	1.4	1.4	1.3	0.9	1.4	0.5	1.1	0.6	1.5	1.5	1.4	0.2	0.5	0.1	1.4	1.4	0.2	0.3	1.5	1.4	0.9	1.5	1.0	1.4
Friendships satisfaction	0.8	1.0	2.4	-1.0	-1.1	-1.0	-0.9	-1.0	-0.1	-0.6	-1.1	-1.2	-1.0	-1.1	-0.9	-0.8	-0.8	-0.7	-1.1	-1.6	0.9	-1.0	-1.0	-1.5	-1.0	-0.6	-1.4
Medication: Blood pressure	0.8	1.4	3.2	1.5	1.4	1.4	1.8	1.4	0.8	0.7	0.0	1.6	1.4	1.5	0.8	0.2	0.6	1.3	1.5	0.8	0.6	1.4	1.5	1.5	1.1	0.8	1.5
Ever smoked	0.8	1.5	2.4	1.4	1.5	1.2	1.0	1.5	0.6	1.6	1.4	1.5	1.5	1.2	1.2	0.5	1.1	1.1	1.5	1.0	0.9	1.3	1.4	1.3	1.0	0.7	1.4
Diabetes (mother)	0.7	0.9	3.4	-0.9	-0.9	-0.7	-1.0	-0.8	-0.3	-0.9	-0.3	-1.1	-0.9	-0.9	-1.5	-0.5	-1.5	-0.6	-0.9	-0.8	-1.8	-0.7	-0.8	-1.0	-1.1	0.1	-1.3
Diabetes (self-reported)	0.7	1.0	2.3	-1.0	-0.9	-1.0	-0.9	-0.9	0.7	-0.9	-1.3	-1.0	-1.1	-1.2	1.1	-1.4	1.5	-1.2	-1.1	-1.5	-0.4	-1.0	-1.0	0.1	-0.9	-1.2	-0.5
Falls in the last year	0.7	1.0	3.2	-1.0	-1.1	-1.1	-1.6	-1.3	0.1	-1.1	-1.0	-0.9	-1.1	-1.1	-0.3	-0.9	-0.2	-1.0	-1.1	-0.1	1.8	-1.0	-1.1	-1.1	-0.8	-0.6	-1.0
Pulse rate	0.7	1.2	4.3	1.1	1.0	1.2	1.6	1.0	-1.1	-0.1	-0.2	0.6	1.1	1.0	-1.1	1.8	-1.3	1.5	1.1	0.6	0.9	1.2	1.1	0.5	0.7	2.1	0.9
Exposure to tobacco smoke at home	0.7	0.8	6.0	-0.6	-0.7	-0.5	-0.1	-0.2	1.8	0.7	-0.1	-0.9	-0.6	-0.7	-1.1	-2.5	-0.9	-0.5	-0.7	-0.5	0.5	-0.7	-0.6	-1.1	-1.0	0.1	-1.3
Medication: Paracetamol	0.7	1.1	4.4	1.1	1.1	1.1	2.1	1.2	1.4	1.5	1.3	1.1	1.1	1.0	-0.3	-0.7	-0.6	1.2	1.0	0.9	-0.3	1.1	1.1	0.8	0.6	1.3	0.7
Medication: Ibuprofen	0.7	0.9	3.2	0.8	0.7	1.1	0.9	0.9	-0.7	0.6	0.1	0.4	0.8	1.0	-1.8	1.0	-1.8	1.5	0.9	-0.0	-0.1	1.0	0.9	0.3	0.0	1.6	0.4
Number of full sisters	0.7	0.9	2.5	-1.0	-1.0	-0.8	-1.2	-0.9	0.2	-0.2	-0.6	-1.1	-1.1	-0.9	-0.4	-0.9	-0.3	-1.2	-1.1	-1.6	-0.6	-1.1	-1.1	-0.4	-1.4	-1.2	-1.2
Leg fat percentage (left)	0.7	2.4	6.0	-1.6	-1.7	-1.6	-1.4	-1.9	-1.9	-2.3	-1.5	-1.5	-1.7	-1.6	-0.8	0.8	-0.7	-1.5	-1.6	-2.4	-0.5	-1.6	-1.6	-0.9	-2.4	-1.4	-1.4
Average weekly beer plus cider intake	0.7	1.0	3.8	1.1	1.0	1.2	1.6	1.2	0.2	1.3	1.9	1.0	1.1	1.1	0.8	0.7	0.7	0.8	1.1	0.9	0.8	0.9	1.0	1.0	1.0	0.9	0.6
Unable to work because of sickness or disability	0.7	0.9	1.6	1.2	1.1	1.1	1.2	1.2	0.6	1.2	0.2	1.1	1.2	1.2	0.1	0.1	0.2	1.3	1.1	1.2	-0.2	1.2	1.2	0.7	1.1	1.2	0.7
Crohns Disease (2012)	0.6	0.9	2.8	1.1	1.3	0.9	0.2	1.1	-0.1	0.8	0.9	0.9	1.2	0.8	0.4	1.0	0.1	0.8	1.2	1.0	-0.2	1.1	1.2	1.2	1.7	1.0	1.4
BMI	0.6	3.6	8.8	-2.3	-2.3	-2.2	-1.6	-2.1	-1.2	-2.0	-1.0	-2.1	-2.3	-2.1	-0.8	-0.4	-0.5	-2.3	-2.2	-2.3	-1.3	-2.3	-2.3	-1.4	-3.0	-1.4	-2.2
Number of treatments/medications taken	0.6	1.0	2.4	1.2	1.0	1.0	1.4	1.2	0.0	0.4	-0.1	1.2	1.2	1.2	-0.8	0.6	-0.9	1.6	1.2	0.5	-0.4	1.2	1.2	0.7	0.8	1.5	1.0
Angina	0.6	0.7	2.7	-0.7	-0.8	-0.9	-0.6	-0.5	0.5	-0.8	-0.9	-0.6	-0.7	-0.9	-1.6	-1.2	-1.6	-0.3	-0.8	-0.5	-1.0	-0.7	-0.7	-0.6	-1.2	0.3	-0.9
Medication: Co-codamol	0.6	0.7	6.4	0.4	0.5	0.5	0.8	0.5	0.6	0.7	0.2	0.2	0.4	0.4	1.5	-0.2	1.5	0.1	0.4	1.5	2.5	0.4	0.4	0.7	1.1	0.0	0.5
Body mass index (BMI)	0.6	2.5	5.3	-1.9	-2.0	-1.9	-1.2	-1.7	-0.1	-1.6	-1.0	-1.7	-1.9	-1.7	-0.5	-1.2	-0.2	-1.8	-1.9	-2.3	-0.1	-1.9	-1.9	-1.3	-2.2	-1.7	-1.8
Alcohol intake versus 10 years previously	0.6	0.9	2.7	-1.1	-0.8	-0.8	-0.9	-1.1	-0.5	-1.1	-0.3	-0.9	-1.0	-0.8	1.5	-0.1	1.6	-1.4	-1.0	-0.7	1.2	-1.0	-1.0	-0.1	-0.8	-1.4	-0.4
Illnesses of mother	0.6	0.7	2.5	1.0	1.0	1.0	0.2	1.2	0.7	1.6	0.2	0.8	1.1	1.0	0.2	0.1	0.0	1.1	1.1	0.4	0.6	0.9	1.0	0.8	1.0	0.8	0.7
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	4.1	-1.2	-1.0	-0.8	-0.4	-1.2	0.2	-0.5	-0.2	-1.3	-1.2	-0.8	0.7	-0.9	0.9	-1.3	-1.2	-0.6	1.1	-1.1	-1.2	-0.7	-0.9	-2.0	-1.2
Forced vital capacity (FVC), Best measure	0.6	2.3	4.1	-1.8	-1.7	-1.8	-2.0	-1.8	0.8	-0.4	-0.8	-1.6	-1.7	-1.9	0.4	-2.0	0.7	-2.0	-1.8	-1.2	-0.8	-1.8	-1.8	-1.0	-1.8	-1.9	-1.7
Comparative body size at age 10	0.6	1.8	5.8	1.2	1.1	1.2	0.7	1.5	2.3	1.9	2.4	0.9	1.2	1.3	0.2	-1.6	0.1	1.4	1.1	0.9	-2.2	1.3	1.2	0.2	1.8	1.1	0.5
Number of children fathered	0.6	0.6	3.3	-0.0	0.2	-0.1	-0.9	-0.0	-1.0	-0.7	0.4	0.1	0.1	-0.0	1.8	1.2	1.8	-0.5	0.1	0.1	1.5	0.0	0.0	1.3	-0.1	-0.7	0.8
Pulse wave peak to peak time	0.6	0.7	5.8	-0.7	-0.6	-0.7	-0.6	-0.6	1.9	0.5	0.2	-0.8	-0.7	-0.7	0.1	-2.4	0.4	-0.7	-0.8	-0.5	0.4	-0.7	-0.7	-0.8	-0.1	-0.3	-0.9
Eye problems/disorders: None of the above	0.6	0.7	2.6	0.7	0.6	0.8	0.8	0.6	1.6	1.3	1.2	0.5	0.7	0.8	-0.7	-1.2	-0.7	0.9	0.6	1.1	0.8	0.7	0.7	0.2	0.2	1.4	0.0
Emphysema/chronic bronchitis	0.6	0.7	4.0	-0.6	-0.7	-0.6	-0.1	-0.6	-0.4	-0.7	0.0	-0.7	-0.6	-0.5	-2.0	-0.2	-1.9	-0.2	-0.7	-0.3	-0.1	-0.5	-0.6	-1.2	-1.1	0.6	-1.1
Illnesses of siblings: Diabetes	0.6	0.8	1.9	1.0	0.9	1.2	1.4	1.0	-0.7	0.5	-0.3	0.7	1.1	1.4	-0.3	1.3	-0.3	1.2	1.0	0.4	0.2	1.0	1.0	0.4	0.4	0.9	0.8
Medication for cholesterol	0.6	0.8	2.6	-1.0	-0.8	-1.0	-1.5	-0.7	0.4	0.1	1.6	-1.0	-1.0	-1.0	1.1	-0.9	1.3	-1.4	-1.0	-0.2	0.3	-0.9	-1.0	-0.5	-0.4	-0.9	-0.7
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.2	1.0	1.0	0.8	1.0	1.0	0.5	0.9	-0.4	0.7	1.1	0.9	-0.6	0.1	-0.7	1.1	1.0	0.8	-0.9	0.9	1.0	0.6	0.4	1.1	0.6
Medication: Atorvastatin	0.6	0.8	4.2	-0.4	-0.5	-0.5	-0.5	-0.7	-2.1	-1.9	-1.6	-0.0	-0.4	-0.1	-1.2	1.7	-1.1	-0.1	-0.3	0.4	0.4	-0.3	-0.4	-0.4	-0.8	0.4	-0.1
Pain experienced in last month	0.6	1.0	4.8	1.0	0.7	0.7	0.6	1.0	-0.4	0.8	1.6	1.0	0.9	0.6	-1.0	1.0	-1.3	1.1	1.0	0.7	-2.2	0.7	1.0	-0.4	1.2	1.5	0.7
Bipolar Disorder (2018)	0.5	0.9	3.5	0.7	0.6	0.7	0.6	0.5	-1.5	-0.1	1.0	0.9	0.7	0.9	-1.0	1.9	-1.2	1.1	0.7	1.5	0.9	0.8	0.7	-0.2	0.7	1.3	0.3
Intelligence (Savage-Jansen 2018)	0.5	1.4	7.2	-0.6	-0.3	-0.9	-0.8	-0.4	2.1	0.3	-1.1	-0.3	-0.6	-0.3	2.5	-2.4	2.7	-1.3	-0.7	-0.7	1.6	-0.7	-0.7	0.6	-0.7	-1.1	-0.0
Alzheimer’s Disease (including proxy)	0.5	0.8	1.8	-1.0	-0.9	-0.7	-0.3	-0.9	-1.2	-1.0	-1.0	-1.1	-1.0	-0.7	-0.7	0.5	-0.6	-0.6	-1.0	-1.3	1.1	-0.9	-1.0	-1.3	-0.3	-0.7	-0.6
Primary Biliary Cirrhosis	0.5	0.7	3.7	1.0	0.8	0.6	0.5	0.7	0.2	0.6	0.4	1.1	0.9	0.9	-0.0	0.5	-0.1	1.0	0.9	1.0	1.9	0.8	0.9	0.4	1.1	1.3	0.8
Rheumatoid Arthritis	0.5	0.7	3.1	-0.7	-0.7	-0.6	-1.0	-0.7	-1.0	-1.1	-1.8	-1.0	-0.8	-1.0	-0.5	0.5	-0.5	-0.6	-0.7	-1.0	0.2	-0.7	-0.7	-0.6	-1.2	-0.5	-0.7
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.5	0.7	0.7	0.6	1.2	0.8	0.7	0.6	1.0	0.9	0.6	1.0	0.7	-0.1	0.5	0.6	0.6	0.3	0.7	0.7	0.6	1.2	0.1	0.3	0.7
Medication: Atenolol	0.5	0.6	1.7	0.8	0.7	0.6	1.1	0.9	0.3	0.4	1.3	1.1	0.8	1.2	-0.6	0.1	-0.8	0.9	0.8	0.8	-1.0	0.8	0.8	0.6	0.1	1.0	0.7
Hair/balding pattern: Pattern 2	0.5	0.6	1.9	0.8	0.8	0.9	0.0	0.8	0.1	0.7	0.9	0.9	0.8	0.6	0.9	0.5	0.7	0.4	0.8	0.8	1.0	0.7	0.7	0.9	1.4	0.2	1.3
Fluid intelligence score	0.5	1.0	6.3	-0.4	-0.2	-0.6	-0.7	-0.3	0.9	-0.1	-1.1	-0.3	-0.5	-0.1	2.1	-1.0	2.4	-1.0	-0.5	0.1	2.5	-0.5	-0.5	1.1	-0.9	-1.2	0.1
Illnesses of siblings	0.5	0.7	2.4	-0.8	-0.8	-0.6	-1.4	-0.8	-0.2	-0.9	-0.2	-1.1	-0.8	-0.8	-0.8	-0.3	-0.8	-0.7	-0.8	-0.8	-1.5	-0.8	-0.8	-1.0	-0.4	-0.9	-0.7
Time employed in main current job	0.5	0.5	1.5	0.8	0.6	0.7	1.1	0.8	0.7	1.1	-1.2	0.5	0.8	0.8	-0.5	-0.3	-0.6	1.0	0.8	0.4	0.6	0.8	0.8	0.3	0.1	1.0	0.3
Lung cancer (father)	0.5	0.6	3.0	-0.4	-0.5	-0.4	-0.8	-0.6	0.3	-0.4	-1.0	-0.9	-0.3	-0.5	-1.7	-0.8	-1.7	0.1	-0.5	-0.2	0.6	-0.3	-0.4	-1.5	-0.4	0.4	-0.9
Pulse wave Arterial Stiffness index	0.5	0.6	5.1	0.5	0.4	0.5	0.4	0.4	-1.9	-0.6	-0.4	0.6	0.5	0.5	-0.4	2.2	-0.6	0.6	0.7	0.3	-0.7	0.5	0.5	0.5	-0.2	0.3	0.7
Shortness of breath walking on level ground	0.5	0.6	3.2	-0.1	-0.1	-0.1	-0.2	-0.0	1.8	0.5	1.3	-0.2	-0.1	-0.1	1.4	-1.8	1.7	-0.5	-0.2	0.5	0.1	-0.2	-0.1	0.6	-0.4	-0.6	0.0
Medication: Seretide 50 evohaler	0.5	0.6	6.0	-0.2	-0.4	-0.2	-0.3	-0.4	-0.5	-0.6	-0.2	-0.3	-0.3	-0.1	-2.3	0.1	-2.4	0.2	-0.2	-0.1	-0.1	-0.2	-0.2	-1.1	-0.8	0.2	-0.4
Mean time to correctly identify matches	0.5	0.9	2.0	1.1	1.0	0.9	1.4	0.9	0.2	0.5	1.3	1.2	1.2	0.8	0.9	0.7	0.7	0.8	1.2	1.2	0.1	0.9	1.1	0.9	1.4	0.4	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	3.3	-0.4	-0.4	-0.5	0.3	-0.4	-1.8	-1.3	-0.9	-0.5	-0.4	-0.1	-0.3	1.7	-0.2	-0.3	-0.3	0.2	1.4	-0.3	-0.4	-0.0	-1.4	-0.3	-0.2
Pulse rate, automated reading	0.5	1.5	3.8	1.2	1.1	1.5	1.7	1.3	-1.2	0.4	0.4	0.9	1.2	1.0	-1.3	1.9	-1.7	1.7	1.3	1.3	-0.6	1.3	1.2	0.3	0.7	1.6	0.9
Comparative height size at age 10	0.5	2.6	8.4	-1.2	-1.5	-1.5	-0.6	-1.3	1.2	0.0	-1.5	-1.8	-1.3	-1.3	-2.9	-2.4	-2.6	-0.5	-1.4	-1.3	-1.7	-1.4	-1.3	-2.1	-2.2	0.0	-2.4
Illnesses of father: Heart disease	0.5	0.8	5.9	-0.1	-0.2	0.0	-0.6	-0.1	0.5	-0.3	-1.0	0.2	-0.1	0.1	-2.4	-0.9	-2.4	0.6	-0.2	-0.3	-1.3	0.1	-0.0	-0.9	-0.4	1.1	-0.5
Average weekly red wine intake	0.5	0.7	3.1	-0.7	-0.7	-1.0	-0.8	-0.5	1.1	-0.1	-0.9	-0.7	-0.7	-0.5	-1.1	-1.8	-1.0	-0.5	-0.8	-0.5	-0.2	-0.7	-0.7	-1.4	-0.8	-0.7	-0.7
Illnesses of father: None of the above (group 1)	0.5	0.6	4.9	0.6	0.6	0.5	1.1	0.5	-0.6	0.5	0.1	0.6	0.7	0.6	1.1	1.1	1.1	0.5	0.7	0.5	2.2	0.5	0.6	0.6	0.4	0.1	0.6
Pain type(s) experienced in last month: Hip pain	0.5	0.6	4.2	0.5	0.5	0.4	0.6	0.7	1.6	0.8	2.0	0.6	0.6	0.7	-0.2	-1.3	-0.1	0.8	0.5	1.0	0.6	0.6	0.5	0.4	-0.1	0.8	0.1
LDL Cholesterol	0.4	0.7	3.8	-0.6	-0.7	-0.9	-0.3	-0.5	-1.2	-0.6	-1.7	-0.8	-0.6	-0.9	-0.8	0.6	-0.6	-0.7	-0.6	-0.6	-0.0	-0.8	-0.5	-0.4	-2.0	-0.1	-1.0
Triglycerides	0.4	0.6	1.8	0.8	0.7	0.8	0.9	0.7	-0.8	0.1	-1.3	0.6	0.8	0.9	-0.4	1.2	-0.5	1.1	0.8	0.3	0.6	0.8	0.8	0.3	0.5	1.3	0.6
Height	0.4	8.1	13.2	-3.0	-3.2	-3.2	-3.1	-3.3	0.1	-1.9	-3.4	-3.6	-3.0	-3.1	-2.5	-2.5	-2.0	-2.6	-3.1	-2.1	-3.2	-3.1	-3.0	-3.3	-3.2	-2.4	-3.6
Waist Hip Ratio (WHR)	0.4	1.7	3.4	-1.5	-1.6	-1.4	-1.8	-1.6	0.1	-0.9	-0.2	-1.6	-1.6	-1.6	-1.4	-1.3	-1.2	-1.4	-1.6	-1.1	-0.3	-1.5	-1.5	-1.1	-1.6	-0.5	-1.6
Sensitivity / hurt feelings	0.4	0.7	1.6	0.9	0.9	1.1	1.0	0.8	0.8	1.2	0.7	0.9	0.9	0.9	-0.5	-0.3	-0.7	1.3	0.9	0.9	0.0	1.1	0.9	0.4	0.8	1.0	0.6
Ever used hormone-replacement therapy (HRT)	0.4	0.6	3.0	0.7	0.5	0.5	0.5	0.6	-0.1	0.3	0.7	1.0	0.7	0.4	-0.9	0.5	-1.0	0.9	0.7	0.1	-1.7	0.7	0.7	0.1	0.3	1.5	0.7
Pack years adult smoking proportion	0.4	0.7	2.3	0.6	0.5	0.6	0.6	0.5	1.1	0.7	0.6	0.7	0.5	0.9	-1.1	-0.8	-1.3	0.9	0.5	1.3	-1.4	0.7	0.6	0.2	-0.1	1.5	0.1
Relative age voice broke	0.4	0.6	4.5	-0.1	-0.1	0.3	-0.6	-0.2	-2.1	-1.3	-0.4	-0.2	-0.1	0.2	-0.8	2.1	-1.0	0.3	0.0	0.4	0.6	0.1	-0.1	-0.6	0.5	0.1	0.1
Hearing difficulty/problems with background noise	0.4	0.6	1.6	0.9	0.8	0.6	0.8	0.9	1.3	0.9	0.5	0.7	0.9	0.7	-0.2	-0.8	-0.4	0.9	0.8	1.1	-0.5	0.8	0.9	0.2	0.9	1.2	0.5
Forced vital capacity (FVC)	0.4	1.4	3.3	-1.3	-1.2	-1.4	-1.8	-1.4	0.5	-0.5	-0.9	-1.1	-1.3	-1.3	0.3	-1.3	0.7	-1.5	-1.3	-0.9	-1.1	-1.3	-1.3	-0.7	-1.8	-1.4	-1.2
Qualifications: None of the above	0.4	0.8	2.6	0.7	0.6	0.6	0.6	0.7	1.5	1.3	0.2	0.7	0.8	0.7	-1.3	-1.1	-1.6	0.9	0.6	0.7	-1.4	0.7	0.7	-0.1	0.7	1.4	0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	4.4	-0.4	-0.4	-0.5	-0.2	-0.1	1.7	0.2	0.6	-0.4	-0.3	-0.6	-0.4	-2.1	-0.3	-0.2	-0.5	-0.1	-1.8	-0.4	-0.3	-1.0	0.5	-0.4	-0.5
Hair/balding pattern: Pattern 3	0.4	0.6	2.0	0.8	0.7	0.8	0.7	0.7	-0.3	0.1	0.4	1.0	0.9	1.0	-0.3	0.9	-0.5	0.9	0.9	0.5	-0.8	0.7	0.8	0.4	1.0	1.4	0.6
Noisy workplace	0.4	0.5	3.6	-0.5	-0.6	-0.4	0.0	-0.4	0.1	0.1	0.0	-0.6	-0.5	-0.6	-1.9	-0.7	-1.8	0.0	-0.5	-0.5	-0.5	-0.5	-0.5	-0.9	-1.0	0.0	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.7	0.6	0.6	0.5	0.7	0.8	0.4	1.1	-1.1	0.5	0.5	0.7	1.1	0.0	1.3	0.4	0.5	0.4	0.6	0.6	0.5	0.5	0.9	0.0	0.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.2	-1.0	-0.8	-0.7	-0.3	-0.7	-0.0	-0.5	-0.3	-0.8	-1.0	-0.7	0.8	-0.6	1.2	-1.1	-1.0	0.3	-0.1	-0.9	-1.0	-0.2	-1.3	-1.5	-0.9
Birth weight	0.4	0.9	2.3	1.0	1.1	1.1	1.4	1.0	0.6	0.9	-0.3	0.8	1.0	1.2	1.0	0.1	0.8	0.9	1.0	0.6	0.5	1.0	1.0	1.5	0.9	0.3	1.1
Angina (self-reported)	0.4	0.6	2.6	-0.5	-0.6	-0.7	-0.5	-0.4	0.4	-0.7	-0.7	-0.4	-0.6	-0.7	-1.6	-1.0	-1.6	-0.1	-0.6	-0.2	-1.0	-0.5	-0.5	-0.5	-1.1	0.5	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	3.3	-0.4	-0.2	0.1	-0.7	-0.6	-1.8	-0.8	0.4	-0.5	-0.5	-0.4	0.4	1.7	0.6	-0.3	-0.4	-0.5	0.5	-0.2	-0.4	0.1	-0.6	-0.7	-0.2
Knee pain experienced in last month	0.4	0.6	3.4	0.3	0.4	0.3	1.1	0.4	1.0	0.5	0.7	0.2	0.3	0.3	1.6	-0.6	1.6	-0.2	0.3	0.1	1.8	0.3	0.3	1.2	0.2	-0.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	7.1	-0.2	-0.2	-0.0	0.7	-0.1	2.4	1.1	0.2	-0.4	-0.2	-0.2	-0.5	-2.7	-0.4	-0.0	-0.3	-0.3	-1.8	-0.2	-0.2	-0.3	-0.2	-0.0	-1.0
Diabetes diagnosed by doctor	0.4	0.6	2.6	-0.6	-0.5	-0.7	-0.8	-0.5	0.4	-0.7	-1.6	-0.7	-0.6	-0.8	1.2	-0.9	1.4	-0.8	-0.6	-1.3	-0.2	-0.6	-0.6	0.4	-0.4	-0.7	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.9	0.1	-0.0	0.0	0.8	0.4	0.1	0.6	0.4	0.0	0.0	-0.0	-1.6	-0.3	-1.7	0.6	0.0	0.6	0.4	0.1	0.1	-0.7	-0.3	0.9	-0.6
Osteoarthritis (self-reported)	0.4	0.6	1.3	0.9	0.9	0.8	1.1	0.9	0.6	0.4	0.5	0.8	0.9	1.0	0.4	0.0	0.3	0.8	0.9	0.7	-0.4	1.0	0.9	1.0	0.6	0.5	0.8
Number of self-reported non-cancer illnesses	0.4	0.7	1.8	0.8	0.6	0.6	1.2	1.1	0.8	0.5	-0.3	1.2	0.8	0.9	-1.1	-0.5	-1.2	1.1	0.8	0.6	-1.1	0.8	0.8	0.2	0.1	1.4	0.5
Mother’s age at death	0.4	0.5	4.0	-0.1	-0.1	-0.5	-1.0	-0.4	-1.9	-1.1	-0.8	0.2	-0.1	-0.3	0.1	2.0	-0.0	-0.4	0.0	-0.5	0.1	-0.2	-0.1	0.0	0.2	0.2	0.7
Financial situation satisfaction	0.4	0.4	1.3	0.8	0.7	0.9	0.2	0.7	0.4	0.7	-0.0	0.5	0.8	0.8	-0.8	0.0	-0.9	1.1	0.7	0.1	0.3	0.9	0.8	0.1	0.3	1.2	0.2
Basal metabolic rate	0.4	2.3	11.2	-1.5	-1.6	-1.6	-0.8	-1.1	2.1	-0.2	-1.0	-1.6	-1.5	-1.3	-0.7	-3.4	-0.3	-1.3	-1.6	-1.6	-1.2	-1.6	-1.5	-1.2	-1.9	-1.3	-1.9
Commuting to job workplace: Cycle	0.4	0.5	1.4	-0.7	-0.8	-1.0	-1.2	-0.7	0.2	-0.3	-0.4	-1.1	-0.8	-0.6	-0.8	-0.7	-0.7	-0.7	-0.8	-0.4	0.5	-0.7	-0.7	-1.0	-0.8	0.2	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.8	-0.6	-0.7	-0.6	-0.8	-0.7	-1.1	-1.4	-0.8	-0.4	-0.6	-0.9	-0.4	0.7	-0.4	-0.6	-0.5	-0.1	0.9	-0.7	-0.6	-0.2	-0.7	-0.8	0.1
Basal cell carcinoma (self-reported)	0.4	0.5	2.6	0.7	0.7	0.5	0.3	0.6	-1.1	0.1	-1.4	0.4	0.7	0.4	0.2	1.6	-0.1	0.4	0.8	-0.1	1.0	0.6	0.7	0.9	-0.1	0.7	0.9
Reaction Time	0.3	0.7	1.6	1.0	0.9	0.9	1.2	0.9	0.5	0.8	1.2	0.9	1.0	0.6	0.4	0.3	0.3	0.7	1.0	1.0	0.1	0.7	1.0	0.4	1.3	0.5	1.0
Age at First Birth	0.3	0.5	2.3	-0.6	-0.4	-0.6	-1.4	-0.4	-0.1	-0.5	0.4	-0.4	-0.4	-0.4	1.5	-0.1	1.4	-1.2	-0.5	-0.3	0.3	-0.5	-0.6	0.4	-0.0	-1.4	-0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.2	-0.4	-0.4	-0.6	-1.1	-0.6	-0.6	-0.6	-0.0	-0.6	-0.5	-0.7	0.6	0.4	0.9	-0.8	-0.4	-0.6	0.5	-0.5	-0.5	0.3	-0.3	-0.7	-0.1
Hypothyroidism (self reported)	0.3	0.6	1.8	-0.7	-0.8	-0.6	-0.3	-0.8	0.1	-0.8	0.6	-0.7	-0.8	-0.8	-1.2	-0.6	-1.0	-0.4	-0.8	-0.4	-1.3	-0.7	-0.7	-1.1	-0.9	-0.2	-0.9
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.7	0.4	0.4	0.0	0.3	0.4	0.8	0.0	0.5	0.6	0.3	0.2	0.9	-0.5	1.0	0.2	0.4	0.2	-0.3	0.3	0.4	1.3	-0.1	0.3	0.7
Medication: Metformin	0.3	0.4	3.6	-0.1	0.0	-0.3	-0.7	0.1	0.4	-0.1	-1.9	-0.4	-0.1	-0.1	1.0	-0.5	1.1	-0.3	-0.1	-0.9	-0.3	-0.1	-0.1	0.8	-0.7	-0.1	0.0
Leg fat-free mass (left)	0.3	1.8	10.9	-1.2	-1.4	-1.4	-0.5	-0.9	2.2	-0.0	-0.6	-1.3	-1.2	-1.0	-0.7	-3.3	-0.4	-1.0	-1.4	-1.3	-1.1	-1.3	-1.3	-1.1	-1.7	-1.0	-1.6
Fed-up feelings	0.3	0.5	3.0	0.0	0.0	0.4	0.1	0.1	0.7	0.5	-0.6	-0.2	0.0	-0.1	-1.6	-1.0	-1.7	0.7	-0.1	0.8	-1.3	0.3	0.1	-0.6	-0.3	0.7	-0.7
Qualifications: CSEs or equivalent	0.3	0.5	2.0	-0.6	-0.7	-0.4	0.1	-0.6	0.7	-0.3	0.5	-0.5	-0.5	-0.5	-1.2	-1.2	-1.0	-0.3	-0.6	-0.3	-0.5	-0.6	-0.6	-1.4	-0.4	-0.3	-0.9
Serious illness, injury or assault to yourself	0.3	0.3	2.1	-0.3	-0.2	-0.2	-0.0	-0.2	-1.2	-1.0	-0.5	-0.1	-0.2	-0.7	0.1	1.1	0.2	-0.4	-0.2	-0.0	-1.4	-0.3	-0.3	-0.4	0.4	0.4	0.3
Leg predicted mass (left)	0.3	1.6	10.7	-1.1	-1.3	-1.3	-0.4	-0.7	2.3	0.1	-0.5	-1.2	-1.1	-0.9	-0.6	-3.3	-0.2	-0.9	-1.3	-1.2	-0.9	-1.2	-1.1	-0.9	-1.6	-1.0	-1.5
Had other major operations	0.3	0.4	1.1	0.6	0.7	0.8	0.8	0.5	0.3	0.2	0.7	1.0	0.6	0.4	0.4	0.2	0.3	0.7	0.6	0.7	0.3	0.7	0.6	0.2	0.9	0.4	0.8
Pain all over the body in last month	0.3	0.3	1.4	-0.1	-0.0	-0.0	-0.6	-0.1	-1.2	-0.6	-0.6	0.1	-0.1	-0.5	0.6	1.2	0.4	-0.4	-0.0	1.0	-0.5	-0.1	-0.1	-0.1	0.2	-0.7	0.3
Trunk fat-free mass	0.3	1.7	10.7	-1.1	-1.3	-1.3	-0.4	-0.7	2.4	0.1	-0.9	-1.3	-1.1	-1.1	-0.3	-3.3	0.1	-1.1	-1.3	-1.1	-1.4	-1.3	-1.2	-1.0	-1.3	-1.1	-1.6
Medication: Lansoprazole	0.3	0.3	1.8	-0.4	-0.3	-0.4	-0.5	-0.3	-0.2	-0.0	-1.3	-0.2	-0.4	-0.6	0.9	0.0	0.9	-0.6	-0.4	-0.4	1.4	-0.5	-0.4	0.1	0.1	-0.2	-0.2
Prospective memory result	0.3	0.4	1.9	-0.4	-0.3	-0.4	-0.9	-0.3	0.8	0.3	-0.7	-0.5	-0.4	-0.9	0.5	-1.1	0.5	-0.8	-0.5	-1.0	-1.4	-0.5	-0.4	-0.0	0.5	-0.6	-0.6
Trunk predicted mass	0.3	1.8	10.6	-1.2	-1.3	-1.4	-0.5	-0.8	2.3	0.0	-1.0	-1.4	-1.2	-1.1	-0.3	-3.2	0.0	-1.2	-1.4	-1.2	-1.4	-1.4	-1.2	-1.1	-1.3	-1.1	-1.6
Birth weight of first child	0.3	0.5	1.5	0.5	0.7	0.4	0.5	0.6	-0.2	0.9	1.1	0.8	0.5	0.5	1.1	0.8	0.9	0.0	0.6	1.0	0.1	0.5	0.5	1.2	-0.0	-0.2	0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.1	-0.3	-0.3	-0.4	-0.9	-0.4	-1.3	-1.4	0.7	-0.4	-0.2	-0.3	-0.5	1.1	-0.5	-0.3	-0.2	-0.0	-0.3	-0.3	-0.2	-0.6	0.1	0.6	-0.2
Exposure to tobacco smoke outside home	0.3	0.4	1.5	0.5	0.5	0.7	1.2	0.6	1.0	0.6	0.2	0.3	0.5	0.7	-0.8	-0.9	-0.8	1.0	0.4	0.1	-0.0	0.7	0.5	-0.5	0.9	0.9	-0.1
Qualifications: College or University degree	0.3	0.9	3.9	0.6	0.8	0.3	-0.2	0.7	1.5	0.5	-0.0	0.7	0.6	0.6	2.0	-1.0	1.9	0.1	0.6	1.3	0.9	0.6	0.6	1.3	0.7	-0.1	1.3
Medication: Omeprazole	0.3	0.3	1.4	-0.3	-0.4	-0.3	-0.5	-0.5	-1.2	-1.2	-1.0	-0.1	-0.4	-0.5	-0.8	0.9	-0.8	-0.2	-0.3	0.1	0.4	-0.3	-0.3	-0.1	-0.6	-0.3	0.2
Arm predicted mass (right)	0.3	1.3	6.7	-1.1	-1.2	-1.3	-0.3	-0.7	1.7	0.1	-0.8	-1.2	-1.0	-0.9	-0.5	-2.6	-0.1	-1.1	-1.2	-1.1	-1.6	-1.3	-1.1	-0.9	-1.2	-1.0	-1.4
Whole body fat-free mass	0.3	1.7	11.7	-1.1	-1.3	-1.3	-0.3	-0.7	2.5	0.2	-0.8	-1.3	-1.1	-1.0	-0.4	-3.4	0.0	-1.1	-1.3	-1.2	-1.2	-1.3	-1.2	-0.9	-1.5	-1.0	-1.6
Qualifications: nursing, teaching	0.3	0.4	1.7	-0.7	-0.6	-0.7	-0.2	-0.5	-0.2	-0.2	-1.3	-0.7	-0.7	-0.7	0.2	-0.2	0.4	-0.7	-0.7	-0.9	1.0	-0.6	-0.7	-0.1	-0.6	-0.9	-0.6
Whole body water mass	0.3	1.9	12.6	-1.2	-1.4	-1.4	-0.4	-0.8	2.5	0.2	-0.8	-1.4	-1.2	-1.0	-0.4	-3.5	-0.1	-1.1	-1.4	-1.3	-1.2	-1.4	-1.2	-1.0	-1.5	-1.1	-1.7
Miserableness	0.3	0.5	1.6	0.7	0.8	0.9	0.3	0.5	1.2	0.7	-0.2	0.5	0.7	0.7	0.5	-0.8	0.5	0.8	0.7	1.2	-0.4	0.8	0.8	0.6	0.4	1.0	0.5
Cholesterol lowering medication	0.3	0.5	1.6	0.9	0.7	0.7	1.2	0.7	-0.0	-0.2	-1.1	0.7	0.8	0.6	0.1	0.6	-0.0	0.8	0.9	0.7	-0.1	0.7	0.9	1.1	0.1	0.5	1.0
Pack years of smoking	0.3	0.4	1.6	0.5	0.4	0.4	0.4	0.3	0.8	0.5	0.4	0.6	0.4	0.6	-1.0	-0.6	-1.1	0.7	0.4	1.2	-1.0	0.6	0.5	0.2	-0.2	1.2	0.1
Body Mass Index (BMI) (2010)	0.2	0.3	1.8	0.3	0.4	0.3	0.2	0.3	0.8	0.7	0.2	0.3	0.3	0.2	1.2	-0.5	1.3	0.1	0.2	0.2	0.5	0.3	0.2	0.9	0.6	-0.3	0.3
Coronary Artery Disease (CAD)	0.2	0.2	1.2	-0.1	-0.3	-0.2	-0.8	-0.1	-0.6	-0.0	-0.6	-0.4	-0.2	-0.7	-0.3	0.5	-0.4	-0.2	-0.1	-0.4	0.0	-0.3	-0.2	0.2	-1.1	0.2	-0.4
Respiratory disease	0.2	0.5	1.3	-0.7	-0.8	-0.9	-1.2	-0.7	0.4	-0.5	0.6	-0.5	-0.7	-0.8	-0.9	-1.0	-0.7	-0.6	-0.8	-0.3	-0.8	-0.8	-0.7	-1.1	-0.4	0.3	-1.0
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.2	0.5	0.5	0.5	0.4	0.5	0.6	0.6	0.2	0.6	0.4	0.2	0.3	-0.3	0.3	0.5	0.4	0.4	-1.5	0.4	0.5	0.4	0.4	0.5	0.4
Ever had hysterectomy (womb removed)	0.2	0.3	1.4	-0.3	-0.5	-0.5	-0.7	-0.4	0.8	0.1	0.5	-0.4	-0.4	-0.4	-0.6	-1.2	-0.5	-0.5	-0.4	0.1	-0.3	-0.5	-0.4	-0.4	-0.7	-0.2	-0.4
Impedance of leg (right)	0.2	1.2	8.4	-0.3	-0.3	-0.2	-1.6	-1.0	-2.9	-1.3	-1.4	-0.4	-0.4	-0.5	-1.2	2.7	-1.4	-0.2	-0.2	-0.5	-0.5	-0.3	-0.3	-0.8	-0.7	0.2	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.3	0.5	0.5	0.7	0.4	0.4	0.4	0.5	-0.2	0.5	0.5	0.2	-0.7	-0.1	-0.8	0.7	0.5	0.4	-1.1	0.6	0.5	0.0	0.5	0.6	0.3
Stomach or abdominal pain in last month	0.2	0.2	1.6	-0.0	-0.1	0.1	-0.3	0.0	-0.1	-0.8	-0.0	-0.2	-0.0	0.0	-1.2	-0.1	-1.3	0.5	-0.1	-0.3	0.9	0.1	-0.0	-0.5	-0.8	0.6	-0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.1	-0.2	-0.3	-0.1	-0.4	-0.3	0.1	-0.6	-0.3	0.0	-0.3	-0.4	-1.0	-0.3	-1.0	0.0	-0.3	0.2	-0.7	-0.2	-0.3	-0.8	0.3	-0.3	-0.4
Medication: Levothyroxine sodium	0.2	0.4	2.0	0.3	0.3	0.5	1.1	0.3	1.4	0.7	1.3	0.5	0.3	0.3	0.2	-1.2	0.2	0.4	0.3	-0.0	-0.4	0.3	0.3	0.5	-0.2	-0.4	0.0
Impedance of leg (left)	0.2	0.9	8.9	0.2	0.2	0.4	-0.8	-0.5	-2.8	-0.8	-1.0	0.0	0.1	0.0	-0.7	3.0	-0.9	0.2	0.3	-0.2	-0.3	0.2	0.2	-0.1	-0.3	0.6	0.0
Number of incorrect matches in round	0.2	0.4	1.5	0.7	0.5	0.5	0.4	0.7	0.1	0.5	0.6	1.0	0.6	0.5	-0.2	0.4	-0.4	0.7	0.6	0.4	1.2	0.6	0.6	0.3	0.9	0.8	0.7
Alcohol usually taken with meals	0.2	0.4	2.1	0.5	0.5	0.5	0.6	0.5	-1.0	0.2	-0.4	0.2	0.6	0.5	-0.3	1.4	-0.3	0.7	0.7	0.8	0.4	0.6	0.6	-0.1	0.9	0.3	0.8
Had menopause	0.2	0.3	1.3	-0.2	-0.1	-0.4	0.8	-0.2	-1.0	-0.4	-0.6	0.0	-0.2	-0.2	1.1	0.9	1.1	-0.5	-0.1	-0.7	-0.2	-0.3	-0.2	0.3	0.4	-0.6	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.5	-0.4	-0.5	-0.5	-0.6	-0.5	-0.8	-0.6	-0.5	-0.9	-0.4	-0.8	-0.1	0.5	-0.1	-0.5	-0.4	-0.4	-0.9	-0.4	-0.4	-0.1	-1.2	-0.3	-1.2
Allergy	0.2	0.4	2.4	0.2	0.2	0.4	0.4	0.1	-1.2	0.1	-0.5	0.0	0.2	0.5	0.9	1.6	1.0	0.0	0.3	0.3	1.2	0.1	0.2	0.8	0.1	-0.7	0.4
Medication: Ramipril	0.2	0.2	1.7	-0.0	0.2	-0.0	-0.0	0.0	-0.3	-0.4	-0.8	0.2	0.0	0.1	1.2	0.4	1.3	-0.4	0.0	-0.5	-0.6	0.0	0.0	0.4	0.7	-0.2	0.5
Impedance of arm (right)	0.2	0.9	3.1	-0.7	-0.6	-0.6	-1.8	-1.2	-1.2	-1.0	-1.2	-0.9	-0.8	-0.5	-1.5	0.6	-1.6	-0.2	-0.7	-0.9	0.0	-0.5	-0.7	-1.0	-1.4	0.0	-1.0
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.8	-0.6	-0.5	-0.6	0.0	-0.6	0.0	-0.9	-0.8	-0.4	-0.6	-0.5	1.1	-0.3	1.3	-0.8	-0.6	-0.1	0.0	-0.6	-0.6	0.2	-0.8	-1.1	-0.0
Mouth/teeth dental problems: Dentures	0.2	0.4	2.0	0.5	0.5	0.6	0.4	0.7	-0.7	0.5	0.5	0.3	0.5	0.7	0.2	1.1	-0.1	0.5	0.5	0.6	1.4	0.5	0.5	0.8	0.7	0.6	0.4
Asthma	0.2	0.4	3.0	0.2	0.2	-0.2	-0.5	0.3	1.7	0.4	0.6	0.5	0.1	-0.1	0.8	-1.6	0.8	-0.2	0.1	0.5	-0.2	0.0	0.1	-0.1	0.8	0.5	0.3
Medication: Cholesterol lowering	0.2	0.4	2.6	0.4	0.3	0.1	0.1	0.4	0.6	0.2	-0.2	0.4	0.4	0.2	-0.9	-0.5	-0.9	0.6	0.3	0.1	-1.6	0.3	0.4	0.1	0.3	1.5	0.3
Depression (self-reported)	0.2	0.2	1.3	0.2	0.2	0.4	0.3	0.3	-0.8	-0.3	1.1	0.3	0.2	0.1	-0.1	0.9	-0.1	0.2	0.3	1.0	0.5	0.2	0.2	-0.2	0.6	-0.4	0.3
Impedance of arm (left)	0.2	0.8	2.9	-0.8	-0.7	-0.6	-1.7	-1.3	-1.6	-1.1	-0.8	-0.9	-0.8	-0.6	-0.9	1.1	-0.9	-0.4	-0.7	-1.0	0.0	-0.5	-0.7	-0.8	-1.3	-0.3	-0.9
Standing height	0.2	1.7	5.3	-1.0	-1.2	-1.2	-1.0	-1.2	1.3	0.0	-1.4	-1.5	-1.1	-1.0	-1.4	-2.2	-1.1	-0.7	-1.2	-0.9	-2.3	-1.1	-1.1	-1.2	-1.8	-0.4	-1.9
Breastfed as a baby	0.2	0.2	1.0	-0.3	-0.2	-0.4	-0.9	-0.3	-0.1	-0.2	-0.7	-0.3	-0.3	-0.3	0.6	-0.0	0.6	-0.5	-0.3	-0.9	0.6	-0.3	-0.3	-0.2	0.2	-1.0	0.1
Hair/balding pattern: Pattern 4	0.2	0.5	2.1	0.7	0.8	0.6	0.8	0.4	-0.8	0.2	1.5	0.6	0.7	0.3	0.7	1.3	0.7	0.5	0.7	0.8	0.4	0.8	0.7	1.0	0.5	0.3	0.5
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.9	-0.3	-0.3	-0.3	-0.2	-0.5	-0.8	-1.4	-0.6	-0.1	-0.3	-0.5	0.5	0.6	0.7	-0.3	-0.3	0.6	-0.9	-0.3	-0.4	-0.6	0.2	-0.7	0.0
Glaucoma (self-reported)	0.2	0.2	1.0	0.1	0.2	0.0	-0.4	0.1	-0.8	0.0	-0.6	0.5	0.1	-0.1	0.7	0.8	0.7	0.1	0.2	0.3	0.5	0.2	0.1	-0.0	1.0	-0.3	0.4
Arm fat-free mass (right)	0.2	1.2	7.6	-0.9	-1.1	-1.1	-0.2	-0.5	2.0	0.3	-0.7	-1.1	-0.9	-0.8	-0.2	-2.8	0.2	-1.0	-1.1	-1.0	-1.4	-1.1	-1.0	-0.7	-1.0	-1.0	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	0.2	0.0	0.0	0.1	0.2	-0.7	-0.0	0.4	-0.1	0.3	0.4	-0.8	0.8	-0.8	0.5	0.3	0.1	1.1	0.2	0.2	-0.5	-0.3	0.9	-0.3
Age at first live birth	0.2	0.3	1.7	-0.3	-0.1	-0.2	-1.2	-0.3	-0.1	-0.3	0.3	-0.4	-0.3	-0.2	1.2	0.1	1.3	-0.6	-0.2	-0.6	-0.1	-0.3	-0.3	0.5	0.2	-1.1	0.2
Health satisfaction	0.2	0.2	1.3	-0.3	-0.3	-0.3	-0.1	-0.3	-0.4	-0.5	-0.2	-0.2	-0.3	-0.4	-0.9	0.1	-0.8	0.1	-0.3	-0.3	-1.1	-0.2	-0.2	-0.6	-0.6	0.5	-0.6
Migraine (self-reported)	0.2	0.3	2.4	0.1	0.2	0.5	0.7	0.3	1.6	0.7	-0.2	0.2	0.2	0.1	0.7	-1.5	0.6	-0.0	0.1	0.1	-0.0	0.2	0.1	0.3	0.6	-0.5	0.2
Overall health rating	0.2	0.5	1.1	-0.7	-0.8	-0.7	-0.6	-0.7	-0.6	-1.0	-0.7	-0.9	-0.8	-0.7	-0.8	0.0	-0.7	-0.5	-0.8	-0.3	-0.2	-0.7	-0.7	-0.9	-0.9	-0.1	-1.0
Had major operations	0.2	0.3	5.1	-0.1	-0.1	-0.1	-0.0	-0.1	0.4	-0.0	0.1	0.1	-0.2	-0.1	-0.4	-0.6	-0.3	0.2	-0.2	0.4	2.3	0.0	-0.1	-0.3	-0.2	0.5	-0.0
Age at last live birth	0.2	0.3	1.6	-0.3	-0.2	-0.2	-1.3	-0.5	0.2	-0.5	0.8	-0.4	-0.3	-0.1	1.1	-0.3	1.3	-0.5	-0.3	-0.1	-0.2	-0.3	-0.3	0.6	-0.2	-0.8	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.2	-0.6	-0.4	-0.2	-0.9	-0.6	-1.1	-0.5	0.1	-0.6	-0.5	-0.2	0.5	0.8	0.6	-0.5	-0.5	-0.7	-0.5	-0.4	-0.5	-0.3	-0.2	-0.4	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.2	0.3	0.4	0.5	-0.5	0.3	-0.4	0.4	-0.1	1.1	0.4	0.3	0.1	0.6	0.0	0.4	0.4	0.8	0.9	0.4	0.3	0.4	-0.2	0.5	0.8
Leg fat-free mass (right)	0.2	1.2	10.9	-0.8	-0.9	-0.9	0.0	-0.4	2.6	0.5	-0.2	-0.9	-0.8	-0.5	-0.2	-3.3	0.2	-0.7	-1.0	-1.0	-0.8	-0.9	-0.8	-0.5	-1.3	-0.7	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.8	-0.6	-0.5	-0.4	-0.4	-0.9	0.1	-0.7	-0.7	-0.7	-0.7	-0.8	0.4	-0.4	0.4	-0.8	-0.6	-0.3	-0.9	-0.5	-0.6	-0.1	-0.4	-0.8	-0.3
Back pain experienced in last month	0.2	0.3	3.2	-0.1	-0.1	0.0	-0.0	-0.0	1.5	0.4	0.1	0.1	-0.1	-0.1	-0.3	-1.8	-0.1	0.2	-0.3	0.7	1.2	-0.0	-0.1	-0.3	-0.1	0.0	-0.4
Asthma (self-reported)	0.2	0.5	3.4	0.3	0.3	-0.1	-0.3	0.4	1.8	0.6	1.1	0.6	0.3	0.0	0.9	-1.6	1.0	-0.1	0.2	0.6	-0.0	0.1	0.3	0.2	1.0	0.6	0.4
Leg predicted mass (right)	0.2	1.2	11.0	-0.7	-0.9	-0.9	0.1	-0.3	2.6	0.6	-0.2	-0.9	-0.7	-0.5	-0.2	-3.3	0.1	-0.6	-0.9	-0.9	-0.9	-0.8	-0.8	-0.4	-1.2	-0.7	-1.2
Ever taken oral contraceptive pill	0.2	0.3	0.9	0.4	0.3	0.3	0.6	0.6	0.7	0.8	0.4	0.4	0.5	0.4	-0.9	-0.5	-0.9	0.7	0.4	-0.0	-0.6	0.4	0.5	-0.4	-0.1	0.7	-0.1
Commuting to job workplace: Public transport	0.2	0.2	0.8	-0.3	-0.5	-0.6	-0.6	-0.4	-0.8	-0.5	-0.9	-0.2	-0.3	-0.6	-0.8	0.5	-0.9	-0.1	-0.3	0.4	0.5	-0.3	-0.3	-0.5	-0.3	-0.2	-0.4
Eye problems/disorders: Glaucoma	0.2	0.3	1.7	-0.0	0.1	0.0	-0.5	-0.0	-1.3	-0.2	-1.1	0.3	0.0	-0.1	0.3	1.3	0.2	0.1	0.1	-0.0	0.4	0.2	0.0	-0.2	1.0	-0.2	0.2
Medication: Paracetamol	0.2	0.3	0.8	-0.6	-0.5	-0.5	0.6	-0.5	-0.0	-0.4	0.1	-0.4	-0.6	-0.6	-0.8	-0.4	-0.8	-0.3	-0.6	-0.2	-0.4	-0.5	-0.6	-0.6	-0.9	-0.4	-0.5
Alcohol drinker status: Never	0.2	0.2	1.5	-0.0	-0.0	-0.1	-0.5	0.1	1.0	0.4	0.2	0.1	-0.0	0.1	-0.6	-1.2	-0.5	0.3	-0.1	1.0	-0.3	0.0	-0.0	-0.4	-0.1	0.2	-0.4
Arm fat-free mass (left)	0.2	1.1	7.8	-0.8	-1.0	-1.0	-0.2	-0.5	2.1	0.2	-0.9	-1.0	-0.8	-0.7	-0.2	-2.8	0.0	-0.8	-1.0	-1.1	-1.2	-1.0	-0.9	-0.6	-1.2	-0.8	-1.2
Number of operations (self-reported)	0.2	0.3	1.5	0.5	0.4	0.4	1.2	0.5	1.0	0.2	0.6	0.7	0.5	0.2	-0.5	-0.7	-0.6	0.7	0.5	0.3	0.1	0.5	0.5	-0.1	-0.2	0.6	0.6
Age started oral contraceptive pill	0.2	0.3	1.3	-0.3	-0.1	-0.5	-0.1	-0.2	-0.6	-0.2	-0.8	-0.1	-0.2	-0.4	1.1	0.6	1.0	-0.7	-0.2	-0.6	0.4	-0.4	-0.3	0.4	0.3	-0.6	0.5
Myopia	0.2	0.3	1.3	-0.4	-0.3	-0.4	0.4	-0.2	-0.1	-0.6	-0.8	0.0	-0.4	-0.5	1.1	-0.0	1.1	-0.8	-0.3	0.9	0.9	-0.5	-0.4	0.4	-0.0	-1.0	0.4
Impedance of whole body	0.2	0.8	6.3	-0.3	-0.2	-0.1	-1.4	-0.9	-2.5	-1.0	-1.1	-0.4	-0.4	-0.2	-0.8	2.4	-0.9	-0.1	-0.2	-0.5	0.0	-0.1	-0.3	-0.4	-0.8	0.2	-0.4
Arm predicted mass (left)	0.2	1.1	7.9	-0.8	-1.0	-1.0	-0.2	-0.5	2.1	0.3	-0.8	-1.1	-0.8	-0.8	-0.2	-2.8	0.1	-0.9	-1.0	-1.1	-1.1	-1.0	-0.9	-0.6	-1.2	-0.8	-1.3
Depressed Affect (Nagel 2018)	0.1	0.2	0.8	0.1	0.0	0.2	0.3	-0.0	0.4	0.1	-0.9	-0.1	-0.0	-0.2	-0.5	-0.6	-0.6	0.4	-0.0	0.1	-0.8	0.2	0.1	0.2	-0.8	0.5	-0.5
Depression (Nagel 2018)	0.1	0.2	1.5	0.4	0.3	0.1	0.2	0.3	0.2	0.3	-0.5	0.2	0.4	0.1	-0.3	0.0	-0.4	0.4	0.4	-0.4	-1.2	0.4	0.4	0.3	-0.0	0.7	0.1
Heel T-Score	0.1	0.7	2.3	-0.7	-0.8	-1.1	-0.0	-0.6	0.3	-0.8	-1.3	-1.5	-0.7	-0.7	-0.7	-0.9	-0.6	-0.7	-0.8	-1.3	0.6	-0.7	-0.7	-1.2	-0.1	0.2	-1.0
Allergy or Eczema	0.1	0.2	3.1	-0.0	-0.1	-0.3	-0.3	-0.1	0.1	-0.5	0.8	-0.0	-0.1	-0.4	-0.4	-0.2	-0.5	-0.0	-0.1	-0.2	-1.8	-0.1	-0.1	-0.3	-0.0	0.2	-0.0
Type 2 Diabetes (T2D) (2018)	0.1	0.1	1.9	0.1	0.1	0.1	-0.5	0.1	0.0	-0.1	0.2	-0.1	0.0	-0.1	0.4	-0.1	0.5	0.1	0.0	-0.7	-1.4	0.1	0.1	0.5	0.1	0.5	-0.0
Lung FVC	0.1	0.5	3.2	0.1	0.3	-0.2	-0.8	0.1	-0.2	0.5	0.7	0.6	0.1	-0.3	1.8	0.5	1.8	-0.6	0.2	0.9	-0.5	0.0	0.1	1.1	0.2	-0.6	0.6
Hand grip strength (left)	0.1	0.3	1.4	0.4	0.5	0.5	0.5	0.5	-0.2	0.8	0.3	0.1	0.3	0.9	0.6	0.6	0.7	0.6	0.4	0.2	1.2	0.5	0.4	0.4	0.5	0.6	0.1
Hand grip strength (right)	0.1	0.2	0.9	-0.4	-0.4	-0.4	-0.5	-0.2	-0.5	0.3	0.3	-0.7	-0.4	-0.0	0.0	0.3	0.2	-0.3	-0.3	-0.5	0.9	-0.4	-0.4	-0.2	-0.3	0.0	-0.6
Townsend deprivation index at recruitment	0.1	0.1	0.8	0.4	0.3	0.3	0.9	0.3	0.1	0.5	-0.2	0.2	0.3	0.5	-0.1	0.1	-0.1	0.2	0.3	0.3	0.3	0.3	0.3	0.1	0.2	0.7	0.3
Taking other prescription medications	0.1	0.1	1.0	-0.0	-0.0	-0.1	-0.1	-0.1	-0.6	-0.7	-1.0	-0.0	0.0	-0.0	-0.3	0.6	-0.3	0.1	0.0	-0.3	0.0	-0.0	0.0	-0.2	-0.0	0.2	0.2
Age when periods started (menarche)	0.1	0.3	1.7	0.0	-0.1	0.0	0.2	-0.3	-1.3	-0.8	-0.7	-0.1	0.1	-0.0	-0.9	1.3	-1.1	0.1	0.1	-0.0	-0.4	-0.0	0.0	-0.4	0.1	0.2	-0.0
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.5	0.3	0.3	0.4	0.4	0.2	0.6	0.1	0.5	0.4	0.3	0.5	0.6	-0.3	0.6	0.2	0.3	0.7	-0.3	0.3	0.3	0.7	0.0	-0.3	0.3
Sitting height	0.1	1.0	5.6	0.6	0.6	0.5	0.7	0.7	2.4	1.9	-0.2	0.5	0.6	0.7	-0.4	-2.1	-0.2	0.9	0.5	1.0	-1.8	0.7	0.6	0.2	0.1	0.9	-0.3
Mouth/teeth dental problems	0.1	0.1	0.5	-0.3	-0.3	-0.4	-0.4	-0.2	0.4	0.1	0.2	-0.2	-0.2	-0.2	-0.5	-0.7	-0.5	-0.2	-0.2	-0.7	-0.5	-0.3	-0.2	-0.2	-0.7	-0.0	-0.3
Pulse wave reflection index	0.1	0.1	0.5	0.2	0.2	0.3	0.0	0.2	-0.2	-0.0	0.6	0.5	0.2	0.3	0.6	0.4	0.4	-0.0	0.3	0.6	-0.4	0.2	0.2	0.7	-0.2	-0.5	0.4
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.8	0.1	0.1	0.2	-0.2	0.1	0.9	0.7	0.5	0.1	0.1	0.2	0.2	-0.9	0.2	0.3	0.0	0.1	0.8	0.2	0.1	-0.1	0.6	0.2	-0.1
Headache pain in last month	0.1	0.2	1.2	0.0	0.1	0.2	-0.2	-0.2	0.1	-0.5	-1.1	-0.2	-0.0	0.3	-0.5	-0.2	-0.6	0.2	-0.1	0.3	1.1	0.2	0.0	0.1	-0.9	0.2	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.9	-0.0	-0.1	0.1	0.5	-0.1	0.5	0.0	1.4	0.1	-0.1	-0.0	-0.2	-0.5	-0.1	0.1	-0.1	0.2	-1.1	-0.0	-0.0	-0.0	-0.2	-0.1	-0.2
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.6	-0.3	-0.3	-0.6	-0.7	-0.3	0.1	-0.2	-0.6	-0.1	-0.3	-0.7	-0.0	-0.4	0.1	-0.3	-0.3	0.8	0.5	-0.3	-0.3	-0.4	0.5	0.2	-0.5
Number of full brothers	0.1	0.1	0.8	-0.1	0.0	-0.2	0.2	-0.2	0.1	-0.1	-0.3	0.0	-0.1	-0.0	0.9	-0.2	0.9	-0.4	-0.1	0.4	0.6	-0.0	-0.1	0.5	0.1	-0.1	0.1
Wheeze or whistling in the chest in last year	0.1	0.1	0.8	0.1	0.1	-0.2	0.4	0.2	0.2	0.3	-0.1	0.1	0.1	0.1	0.9	-0.0	0.8	-0.3	0.2	0.5	-0.1	0.0	0.1	0.4	0.4	-0.3	0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.2	1.6	-0.2	-0.2	-0.2	-0.6	-0.3	1.1	0.1	-0.3	0.0	-0.3	-0.3	0.0	-1.3	0.1	-0.0	-0.3	0.5	0.3	-0.1	-0.2	0.2	-0.3	0.2	-0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.4	-0.3	-0.2	-0.6	-0.5	-0.4	-0.2	-0.3	-0.6	0.1	-0.3	-0.4	-0.1	-0.1	-0.2	-0.3	-0.3	0.3	0.5	-0.2	-0.3	0.1	-0.7	-0.1	-0.0
Long-standing illness, disability or infirmity	0.1	0.2	0.9	0.1	0.0	0.0	-0.4	0.1	-0.2	-0.6	-0.8	-0.0	0.1	0.3	-0.7	0.1	-0.8	0.4	0.1	0.5	-0.7	0.2	0.2	-0.5	0.6	1.0	-0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.9	0.2	-0.0	-0.2	0.5	0.2	0.5	-0.0	0.6	0.1	0.2	-0.2	-0.9	-0.6	-0.9	0.3	0.1	0.0	0.3	-0.1	0.2	-0.3	-0.1	0.6	0.0
Diastolic blood pressure, automated reading	0.1	0.2	1.3	-0.2	-0.2	-0.1	0.1	-0.3	-1.0	-0.6	-0.6	-0.0	-0.2	-0.2	0.2	0.9	0.1	-0.3	-0.1	-1.1	0.3	-0.2	-0.2	0.4	-0.7	-0.7	0.2
Hair Pigment	0.0	0.8	4.8	0.6	0.5	0.7	1.2	0.7	-0.5	0.7	1.6	0.4	0.6	0.3	-1.2	0.8	-1.2	0.8	0.6	1.1	-2.2	0.6	0.6	0.0	0.5	0.6	0.4
Tanning	0.0	0.2	1.0	-0.2	-0.1	-0.2	-0.7	-0.4	0.7	-0.1	-0.5	-0.4	-0.2	-0.1	-0.1	-1.0	0.4	-0.1	-0.3	-0.5	-0.7	-0.2	-0.2	-0.2	-0.4	0.5	-0.7
Hayfever, allergic rhinitis or eczema	0.0	0.1	1.3	-0.1	-0.1	-0.1	-0.2	-0.0	0.3	-0.3	0.4	-0.0	-0.1	-0.4	-0.1	-0.4	-0.2	-0.0	-0.1	-0.4	-1.1	-0.1	-0.0	-0.2	-0.1	0.0	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.4	-0.0	0.0	0.1	-0.5	-0.1	0.6	0.3	-0.5	-0.1	-0.1	-0.1	-0.2	-0.7	-0.2	0.2	-0.1	0.2	-0.1	0.1	-0.0	-0.2	-0.4	0.1	-0.3
Alcohol intake frequency.	0.0	0.1	0.5	-0.1	0.0	0.2	-0.1	-0.1	-0.5	-0.4	-0.7	-0.0	-0.1	0.0	0.1	0.4	0.2	0.2	-0.1	0.5	-0.6	0.2	-0.0	0.2	-0.4	-0.1	-0.2

Hub : Genes

THAP9-AS1

Models

Trait associations