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chr5:154,607,639-157,178,219

Best TWAS P=1.74e-24 · Best GWAS P=2.5e-24 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	TIMD4	0.12	0.13	lasso	5	0.12	3.1e-24	10.2	10.2	1.7e-24	1.00	0.00	1.00	TRUE
2	GTEx	Artery Aorta	SGCD	0.26	0.09	enet	29	0.18	2.2e-10	3.8	5.7	1.5e-08	0.13	1.00	0.00	TRUE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TIMD4	0.28	0.26	lasso	5	0.26	7.4e-18	10.2	10.1	4.5e-24	0.98	0.00	1.00	FALSE
6	The Cancer Genome Atlas	Glioblastoma Multiforme	TIMD4	0.26	0.18	lasso	5	0.16	1.4e-05	10.2	10.0	1.9e-23	1.00	0.00	0.99	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	TIMD4	0.09	0.05	blup	41	0.05	1.7e-06	10.2	9.7	3.1e-22	0.85	0.00	1.00	FALSE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TIMD4	0.03	0.02	blup	41	0.02	2.3e-03	10.2	8.3	7.0e-17	0.83	0.00	0.89	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	TIMD4	0.03	0.02	blup	41	0.03	8.6e-04	8.2	8.3	7.0e-17	0.86	0.01	0.77	FALSE
13	The Cancer Genome Atlas	Stomach Adenocarcinoma	TIMD4	0.06	0.01	blup	41	0.04	1.4e-03	8.2	8.0	1.3e-15	0.86	0.01	0.87	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	TIMD4	0.09	0.04	enet	10	0.06	1.1e-07	10.2	8.0	1.5e-15	0.82	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Soft Tissue Sarcoma	TIMD4	0.08	0.06	lasso	4	0.04	2.1e-03	6.8	7.5	5.2e-14	0.64	0.03	0.80	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	TIMD4	0.10	0.03	blup	41	0.04	3.7e-03	4.6	6.0	1.6e-09	0.69	0.02	0.46	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HAVCR1	0.09	0.08	enet	14	0.10	8.8e-12	4.6	-5.5	4.0e-08	-0.46	1.00	0.00	FALSE
3	METSIM	Adipose	TIMD4	0.03	0.01	enet	6	0.02	1.6e-03	7.4	5.2	1.8e-07	0.32	0.12	0.04	FALSE