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chr5:154,607,639-157,178,219

Best TWAS P=1.74e-24 · Best GWAS P=2.5e-24 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HAVCR1 0.09 0.08 enet 14 0.10 8.8e-12 4.6 -5.5 4.0e-08 -0.46 1.00 0.00 FALSE
2 GTEx Artery Aorta SGCD 0.26 0.09 enet 29 0.18 2.2e-10 3.8 5.7 1.5e-08 0.13 1.00 0.00 TRUE
3 METSIM Adipose TIMD4 0.03 0.01 enet 6 0.02 1.6e-03 7.4 5.2 1.8e-07 0.32 0.12 0.04 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma TIMD4 0.12 0.13 lasso 5 0.12 3.1e-24 10.2 10.2 1.7e-24 1.00 0.00 1.00 TRUE
5 The Cancer Genome Atlas Colon Adenocarcinoma TIMD4 0.10 0.03 blup 41 0.04 3.7e-03 4.6 6.0 1.6e-09 0.69 0.02 0.46 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme TIMD4 0.26 0.18 lasso 5 0.16 1.4e-05 10.2 10.0 1.9e-23 1.00 0.00 0.99 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TIMD4 0.03 0.02 blup 41 0.02 2.3e-03 10.2 8.3 7.0e-17 0.83 0.00 0.89 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma TIMD4 0.09 0.04 enet 10 0.06 1.1e-07 10.2 8.0 1.5e-15 0.82 0.00 1.00 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma TIMD4 0.09 0.05 blup 41 0.05 1.7e-06 10.2 9.7 3.1e-22 0.85 0.00 1.00 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TIMD4 0.28 0.26 lasso 5 0.26 7.4e-18 10.2 10.1 4.5e-24 0.98 0.00 1.00 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma TIMD4 0.03 0.02 blup 41 0.03 8.6e-04 8.2 8.3 7.0e-17 0.86 0.01 0.77 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma TIMD4 0.08 0.06 lasso 4 0.04 2.1e-03 6.8 7.5 5.2e-14 0.64 0.03 0.80 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma TIMD4 0.06 0.01 blup 41 0.04 1.4e-03 8.2 8.0 1.3e-15 0.86 0.01 0.87 FALSE