Best TWAS P=4.59e-13 · Best GWAS P=7.9e-15 conditioned to 0.00483
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | SDC1 | 0.38 | 0.42 | lasso | 3 | 0.42 | 3.3e-16 | -6.1 | 6.3 | 2.3e-10 | -0.81 | 0.92 | 0.08 | FALSE |
2 | YFS | Blood | HS1BP3 | 0.03 | 0.00 | blup | 536 | 0.01 | 3.7e-04 | 2.7 | -6.2 | 5.2e-10 | 0.39 | 0.59 | 0.05 | FALSE |
3 | YFS | Blood | PUM2 | 0.10 | 0.09 | enet | 22 | 0.09 | 2.2e-29 | -7.6 | 7.2 | 4.6e-13 | -0.93 | 0.01 | 0.99 | TRUE |