Best TWAS P=9.08e-11 · Best GWAS P=1.03e-24 conditioned to 8.37e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADCY3 | 0.16 | 0.12 | lasso | 10 | 0.14 | 3.2e-17 | 5.7 | -6.5 | 9.1e-11 | 0.33 | 1.00 | 0.0 | TRUE |
| 2 | GTEx | Whole Blood | ADCY3 | 0.23 | 0.24 | enet | 24 | 0.27 | 5.5e-25 | 5.2 | 5.2 | 2.0e-07 | -0.30 | 1.00 | 0.0 | FALSE |
| 3 | GTEx | Whole Blood | RP11-443B20.1 | 0.21 | 0.17 | enet | 32 | 0.20 | 1.8e-18 | 4.3 | 5.7 | 1.2e-08 | -0.33 | 1.00 | 0.0 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | EFR3B | 0.03 | 0.05 | lasso | 1 | 0.04 | 1.9e-05 | -5.4 | -5.3 | 8.6e-08 | 0.46 | 0.53 | 0.1 | FALSE |