Best TWAS P=8.82e-10 · Best GWAS P=1.76e-08 conditioned to 0.327
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | CTC-435M10.6 | 0.26 | 0.19 | enet | 19 | 0.22 | 5.8e-11 | 4.8 | 5.2 | 1.7e-07 | 0.00 | 0.34 | 0.65 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | B9D2 | 0.08 | 0.05 | blup | 37 | 0.08 | 3.4e-05 | 4.0 | 6.1 | 8.8e-10 | -0.41 | 0.16 | 0.35 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | BCKDHA | 0.03 | 0.03 | enet | 4 | 0.03 | 1.8e-04 | -4.8 | -5.9 | 4.3e-09 | 0.26 | 0.02 | 0.79 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | AXL | 0.05 | 0.02 | blup | 54 | 0.02 | 4.5e-03 | -5.3 | -5.8 | 8.2e-09 | 0.88 | 0.02 | 0.91 | TRUE |