Best TWAS P=1.05e-32 · Best GWAS P=5.29e-73 conditioned to 4.22e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Uterus | NELFCD | 0.58 | 0.07 | lasso | 10 | 0.06 | 2.4e-02 | -3.5 | 5.7 | 1.4e-08 | -0.18 | 0.06 | 0.06 | FALSE |
| 2 | YFS | Blood | ZNF831 | 0.19 | 0.14 | bslmm | 535 | 0.19 | 7.8e-61 | 13.3 | -11.8 | 2.8e-32 | 0.61 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | EDN3 | 0.15 | 0.00 | blup | 70 | 0.00 | 2.1e-01 | -1.8 | -6.9 | 3.9e-12 | 0.30 | 0.01 | 0.06 | FALSE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNF831 | 0.22 | 0.03 | enet | 6 | 0.15 | 9.0e-05 | 2.5 | -11.9 | 1.0e-32 | 0.67 | 0.01 | 0.67 | TRUE |