[Hub]/) : Traits : Hair Pigment : ← →

chr2:134,513,621-136,403,272

Best TWAS P=1.41e-36 · Best GWAS P=1.04e-37 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC100129961	0.17	0.14	enet	9	0.14	2.6e-17	-7.1	-6.0	1.4e-09	0.55	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TMEM163	0.05	0.02	lasso	7	0.01	5.9e-03	4.1	-6.9	6.8e-12	0.63	0.32	0.06	FALSE
3	GTEx	Esophagus Muscularis	TMEM163	0.09	0.05	lasso	6	0.05	4.8e-04	10.4	-10.8	3.4e-27	0.87	0.07	0.91	FALSE
4	GTEx	Heart Atrial Appendage	TMEM163	0.31	0.10	lasso	6	0.03	1.8e-02	10.2	-10.4	1.9e-25	0.82	0.26	0.34	FALSE
5	GTEx	Pituitary	TMEM163	0.37	0.39	lasso	5	0.38	1.9e-10	-12.8	-12.6	1.4e-36	0.99	0.01	0.99	TRUE
6	GTEx	Prostate	AC016725.4	0.27	0.03	enet	23	0.13	4.6e-04	-6.9	-5.8	5.1e-09	0.59	0.12	0.69	FALSE
7	GTEx	Testis	TMEM163	0.29	0.18	lasso	6	0.24	4.5e-11	-8.5	11.0	2.3e-28	-0.88	0.01	0.99	FALSE
8	GTEx	Testis	AC016725.4	0.18	0.09	lasso	6	0.09	6.3e-05	-7.2	8.9	6.3e-19	-0.71	0.44	0.51	FALSE
9	GTEx	Whole Blood	TMEM163	0.11	0.06	lasso	7	0.06	5.0e-06	10.4	-9.8	1.2e-22	0.84	0.72	0.22	FALSE
10	NTR	Blood	CCNT2	0.01	0.00	blup	370	0.00	6.7e-02	2.9	7.3	2.3e-13	-0.68	0.14	0.47	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	TMEM163	0.19	0.16	lasso	14	0.23	6.2e-29	5.5	-8.1	6.4e-16	0.57	1.00	0.00	FALSE
12	YFS	Blood	CCNT2	0.01	0.01	blup	363	0.01	6.3e-05	2.5	7.2	8.7e-13	-0.61	0.53	0.25	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TMEM163	0.03	0.02	blup	195	0.01	2.9e-02	10.4	-11.3	1.4e-29	0.88	0.02	0.89	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM163	0.06	0.09	lasso	7	0.08	1.6e-16	10.4	-11.2	3.1e-29	0.87	0.33	0.67	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	TMEM163	0.08	0.02	blup	192	0.01	8.9e-02	10.4	-11.2	4.3e-29	0.84	0.02	0.80	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM163	0.06	0.04	lasso	8	0.05	8.4e-07	10.4	-10.1	3.9e-24	0.85	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ACMSD	0.04	0.01	blup	46	0.02	2.2e-03	2.8	6.1	1.1e-09	-0.57	0.11	0.33	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM163	0.17	0.21	lasso	5	0.20	1.6e-22	10.4	-10.4	3.1e-25	0.78	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM163	0.33	0.36	enet	18	0.37	4.7e-22	10.4	-10.8	5.3e-27	0.83	0.91	0.09	FALSE
20	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	TMEM163	0.09	0.06	enet	8	0.08	9.0e-05	6.4	-9.2	5.8e-20	0.62	0.16	0.57	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	TMEM163	0.06	0.01	blup	191	0.04	2.6e-05	8.1	-9.4	5.9e-21	0.69	0.29	0.65	FALSE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM163	0.04	0.00	blup	190	0.02	6.1e-03	10.3	-10.4	2.9e-25	0.85	0.06	0.92	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM163	0.07	0.07	enet	8	0.07	2.3e-07	-10.2	-10.0	9.9e-24	0.75	0.62	0.37	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM163	0.14	0.14	lasso	8	0.18	2.4e-17	10.4	-11.5	1.9e-30	0.83	0.07	0.93	FALSE