Best TWAS P=7.12e-11 · Best GWAS P=6.55e-09 conditioned to 0.888
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PLXNA1 | 0.11 | 0.13 | lasso | 5 | 0.14 | 3.5e-11 | -5.6 | 5.7 | 1.1e-08 | -0.70 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | PLXNA1 | 0.12 | 0.12 | lasso | 2 | 0.09 | 1.5e-05 | -5.7 | 5.7 | 1.1e-08 | -0.55 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Nerve Tibial | PLXNA1 | 0.10 | 0.06 | lasso | 4 | 0.06 | 3.4e-05 | -5.8 | 6.5 | 7.1e-11 | -0.88 | 0.01 | 0.99 | TRUE |
| 4 | METSIM | Adipose | PLXNA1 | 0.13 | 0.14 | lasso | 9 | 0.14 | 3.7e-20 | -5.1 | 5.1 | 3.0e-07 | -0.60 | 0.02 | 0.98 | FALSE |