TWAS hub - PLXNA1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1120	0.0350	1.8e-06	0.133	NA	0.118	NA	0.136	5.6e-11	NA	7.1e-10	NA	3.5e-11
2	GTEx	Adipose Visceral Omentum	0.1210	0.0450	5.1e-04	0.125	NA	0.081	NA	0.093	5.3e-07	NA	5.2e-05	NA	1.5e-05
3	GTEx	Lung	0.0955	0.0306	2.7e-05	0.063	NA	0.043	NA	0.057	1.4e-05	NA	3.2e-04	NA	3.6e-05
4	GTEx	Nerve Tibial	0.1045	0.0394	3.0e-04	0.057	NA	0.057	NA	0.062	6.9e-05	NA	7.1e-05	NA	3.4e-05
5	GTEx	Skin Not Sun Exposed Suprapubic	0.1650	0.0730	7.9e-03	-0.003	NA	0.006	NA	-0.001	4.8e-01	NA	1.5e-01	NA	3.5e-01
6	METSIM	Adipose	0.1291	0.0301	8.6e-12	0.143	0.116	0.136	0.137	0.139	9.6e-21	6.1e-17	9.0e-20	7.0e-20	3.7e-20
7	YFS	Blood	0.0240	0.0102	1.1e-03	0.000	0.006	0.003	0.007	0.000	4.4e-01	2.6e-03	3.0e-02	1.9e-03	5.2e-01
8	TCGA	Colon Adenocarcinoma	0.0530	0.0300	7.1e-03	0.073	0.031	0.032	NA	0.060	4.8e-05	6.2e-03	5.7e-03	NA	2.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Prospective memory result	6.7	8.3	19.0	2.3	2.4	2.8	2.0	3.3	2.6	2.6	4.4
Hair/balding pattern: Pattern 4	6.5	15.7	28.3	4.5	4.7	4.2	5.3	3.3	4.4	1.2	2.4
Ever used hormone-replacement therapy (HRT)	5.0	6.3	10.1	2.8	2.5	3.2	2.5	0.9	3.2	1.8	2.5
Number of incorrect matches in round	4.9	8.1	16.0	3.5	3.4	3.2	4.0	1.6	3.3	0.2	1.4
Medication: Atenolol	4.1	5.2	7.1	2.5	2.2	2.7	2.4	0.6	2.6	2.2	2.3
Angina (self-reported)	3.8	5.0	9.2	2.2	2.0	2.1	2.6	1.7	2.0	3.0	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.7	7.8	12.6	-3.5	-3.5	-3.4	-3.2	-0.6	-3.2	-0.8	-2.2
Bilateral oophorectomy (both ovaries removed)	3.6	4.1	7.9	2.3	2.8	2.4	2.1	0.3	2.4	1.4	1.5
Medication for cholesterol	3.5	5.3	9.7	-2.1	-2.2	-2.5	-1.9	-2.0	-2.0	-2.3	-3.1
Coronary Artery Disease (CAD)	3.4	4.0	6.4	1.6	2.0	2.5	1.5	2.3	2.0	1.8	2.1
Blood Platelet Count	3.4	39.4	66.7	-7.5	-7.1	-8.2	-7.3	-4.0	-6.7	-2.9	-4.4
Lung FVC	3.4	17.4	28.4	-5.1	-4.9	-5.3	-4.7	-0.7	-4.7	-1.8	-3.5
Forced vital capacity (FVC), Best measure	3.4	12.3	19.9	-4.2	-4.5	-4.4	-4.0	-0.1	-3.7	-1.6	-3.0
LDL Cholesterol	3.3	5.2	7.1	2.4	2.7	2.6	1.9	1.1	2.4	2.6	2.2
Forced vital capacity (FVC)	3.2	12.5	18.3	-4.2	-4.1	-4.3	-4.3	-0.5	-3.8	-1.8	-3.3
Angina	2.9	3.8	7.7	2.0	1.7	1.8	2.2	1.3	1.7	2.8	1.6
Depression (Nagel 2018)	2.7	4.1	6.5	2.4	1.8	2.4	2.5	0.8	2.5	1.4	1.8
Had menopause	2.7	3.4	4.6	2.0	2.0	1.9	1.9	0.1	2.1	1.9	1.9
Medication: Ventolin 100micrograms inhaler	2.7	3.5	5.0	2.2	2.0	1.7	2.1	1.9	2.2	1.8	0.7
Qualifications: None of the above	2.6	5.6	8.1	2.2	2.4	2.2	1.8	2.6	2.4	2.4	2.8
Breastfed as a baby	2.6	3.3	6.1	-1.7	-1.3	-1.9	-2.5	-1.4	-2.1	-0.2	-2.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	7.9	13.5	-3.2	-3.7	-3.7	-3.0	0.0	-3.1	-1.3	-2.3
Fluid intelligence score	2.4	4.9	10.2	-1.9	-2.1	-2.5	-1.4	-0.8	-1.8	-3.0	-3.2
Birth weight of first child	2.3	4.1	7.3	-2.3	-1.8	-2.3	-1.9	-2.7	-2.0	-0.8	-2.0
Verbal and Numeric Reasoning (VNR)	2.2	5.3	13.3	-2.0	-2.2	-2.7	-1.8	-1.2	-2.1	-2.0	-3.6
Hand grip strength (left)	2.2	5.9	9.8	-2.3	-2.7	-2.6	-2.7	0.1	-2.3	-3.1	-2.6
Forced expiratory volume in 1-second (FEV1)	2.2	7.3	11.8	-3.1	-3.4	-3.3	-3.0	-0.3	-2.9	-1.4	-2.8
Risk taking	2.2	3.2	6.7	1.7	1.9	2.3	1.2	-0.3	2.0	1.4	2.6
Intelligence (Savage-Jansen 2018)	2.1	6.6	11.6	-2.1	-2.6	-3.1	-1.8	-1.5	-2.3	-3.2	-3.4
Bipolar Disorder (2011)	2.1	2.0	5.2	-0.7	-1.0	-1.3	-0.5	-1.9	-1.3	-2.3	-1.5
Mother’s age at death	2.1	2.7	4.7	-1.6	-2.0	-1.9	-1.1	0.6	-2.2	-1.4	-1.8
Trunk fat percentage	2.0	7.9	14.6	3.0	3.8	3.1	3.3	-0.6	3.0	2.2	2.1
Father’s age at death	2.0	2.7	5.1	-1.0	-1.7	-2.0	-0.7	-0.3	-1.9	-2.2	-2.3
Health satisfaction	2.0	2.6	4.7	1.6	1.7	1.7	2.2	0.2	1.6	1.5	1.6
Ever had bowel cancer screening	2.0	2.4	4.9	-1.5	-1.0	-1.6	-1.1	-1.1	-1.8	-2.2	-1.6
Breast cancer (self-reported)	2.0	2.4	4.1	-1.3	-2.0	-1.5	-1.1	-1.5	-1.5	-1.4	-1.8
Commuting to job workplace: Cycle	2.0	2.4	4.0	-2.0	-1.5	-2.0	-1.9	-1.0	-1.7	-0.2	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.3	4.4	1.7	2.1	1.7	1.8	-0.3	1.7	0.2	1.3
Medication: Blood pressure	1.9	3.6	7.4	1.6	1.8	2.1	1.8	0.9	1.7	2.0	2.7
Reaction Time	1.8	3.5	5.7	2.1	1.6	2.4	2.3	0.6	2.2	1.9	1.2
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	4.3	1.9	2.1	2.0	1.5	-0.2	2.0	0.4	0.5
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	4.2	1.4	1.5	1.4	1.2	0.8	1.2	1.4	2.1
Qualifications: A levels/AS levels or equivalent	1.8	4.0	10.4	-1.3	-1.8	-2.1	-1.8	-0.2	-1.9	-3.2	-2.3
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	6.0	-1.2	-1.7	-1.6	-0.7	-1.8	-1.9	-2.4	-1.7
Age at first live birth	1.8	3.2	13.6	-0.7	-1.4	-1.2	-0.7	-1.3	-1.2	-3.7	-2.1
Osteoarthritis (self-reported)	1.8	2.4	6.2	-1.5	-0.8	-1.6	-1.7	-2.5	-1.9	-0.5	-0.5
Medication: Bendroflumethiazide	1.8	2.7	7.8	0.9	1.7	1.3	1.3	0.6	1.5	2.0	2.8
Gout (self-reported)	1.7	2.3	3.9	-2.0	-1.8	-1.9	-2.0	0.2	-1.9	0.7	0.1
Body fat percentage	1.7	6.7	12.1	2.7	3.5	2.9	2.9	-0.7	2.8	2.2	2.1
Lung cancer (father)	1.6	1.9	3.7	1.4	1.2	1.3	1.3	0.5	1.7	1.9	1.3
Ulcerative Colitis	1.5	2.2	3.3	1.4	1.4	1.8	1.7	1.1	1.5	1.1	1.7
Hand grip strength (right)	1.5	4.0	6.7	-1.8	-1.8	-2.6	-1.7	-0.5	-2.0	-2.5	-2.2
Financial difficulties in last 2 years	1.5	2.0	4.2	1.0	2.1	1.5	0.5	0.2	1.5	2.1	1.2
Pulse wave Arterial Stiffness index	1.5	1.8	3.5	1.4	1.3	1.0	1.9	-1.9	1.2	0.4	0.8
Birth weight	1.5	3.2	6.2	-1.7	-2.0	-2.3	-1.6	-0.3	-1.9	-1.0	-2.5
Worry too long after embarrassment	1.5	2.5	5.3	-1.8	-2.3	-1.6	-1.3	-1.6	-2.0	0.3	-0.6
Mean time to correctly identify matches	1.5	2.9	6.2	1.8	1.5	2.0	2.0	-0.1	1.7	2.5	1.1
Headache pain in last month	1.4	2.5	5.1	1.5	1.4	1.6	1.2	0.4	1.7	2.2	1.8
Overall health rating	1.4	3.0	5.5	1.7	1.9	2.3	2.3	0.3	1.6	1.2	1.7
Mineral and other dietary supplements	1.4	1.9	3.6	1.2	0.6	1.9	1.4	1.6	1.6	1.5	0.6
Medication: Lisinopril	1.4	1.8	3.7	1.1	1.9	1.5	1.1	0.9	1.9	0.3	1.4
Neuroticism (2016)	1.3	1.9	3.8	-1.5	-1.7	-1.9	-1.6	0.3	-1.7	0.5	0.8
Leg fat percentage (right)	1.3	4.7	7.2	2.1	2.7	2.4	2.3	-1.1	2.2	2.1	2.1
Pulse wave peak to peak time	1.3	1.5	3.5	-1.3	-1.3	-0.9	-1.7	1.9	-1.0	-0.4	-0.8
Handedness (chirality/laterality): Left-handed	1.3	1.6	3.2	1.4	0.4	1.8	1.0	0.8	1.5	1.4	1.2
Qualifications: nursing, teaching	1.3	2.1	3.1	-1.1	-1.4	-1.6	-0.9	-1.8	-1.8	-1.1	-1.6
Ever had prostate specific antigen (PSA) test	1.3	1.4	3.9	-0.8	-0.4	-1.4	-1.3	-2.0	-1.1	-0.9	-1.2
HDL Cholesterol	1.2	2.0	9.1	0.7	0.9	0.8	-0.3	1.5	0.8	1.4	3.0
Supplements: Glucosamine	1.2	1.5	2.8	-1.0	-0.9	-1.4	-1.5	-1.7	-1.1	-1.3	0.5
Trunk fat mass	1.2	5.0	10.1	2.4	3.2	2.5	2.7	-0.7	2.5	1.3	1.2
Asthma	1.2	2.3	3.5	1.8	1.5	1.5	1.6	0.8	1.9	1.2	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	3.5	1.4	1.3	1.6	0.8	-0.7	1.4	1.4	1.9
Pulse wave reflection index	1.2	1.4	2.5	-0.9	-1.3	-1.5	-1.2	-1.6	-1.1	-1.0	-0.8
Medication: Allopurinol	1.2	1.6	3.3	-1.5	-1.2	-1.6	-1.8	0.7	-1.5	0.2	-0.1
Number of full sisters	1.2	1.4	2.8	1.4	1.1	1.7	1.2	0.3	1.7	0.8	-0.7
Asthma (self-reported)	1.2	2.4	3.5	1.8	1.5	1.6	1.6	0.6	1.9	1.3	1.7
Leg fat percentage (left)	1.2	4.3	6.7	2.1	2.6	2.3	2.3	-1.1	2.1	1.8	1.9
Average weekly beer plus cider intake	1.2	1.8	3.3	-1.3	-1.3	-1.0	-1.4	-1.5	-1.3	0.9	-1.8
Vascular/heart problems diagnosed by doctor	1.2	3.4	7.5	-1.5	-1.7	-1.6	-1.3	-0.7	-1.7	-2.6	-2.7
Basal cell carcinoma (self-reported)	1.2	1.4	4.3	-0.4	-0.3	-1.0	1.0	-1.5	-0.7	-1.5	-2.1
Ulcerative Colitis (UC)	1.1	2.0	4.4	1.4	1.7	1.6	2.1	0.4	1.4	0.6	1.2
Body Mass Index (BMI) (2010)	1.1	1.5	2.6	1.3	1.1	1.1	1.3	1.6	0.9	1.6	0.7
Cardiovascular Disease	1.1	3.6	4.9	2.0	1.8	2.2	1.8	0.3	2.1	2.2	2.1
Ever had hysterectomy (womb removed)	1.1	1.2	2.4	1.2	1.2	0.7	1.6	-0.3	1.2	1.0	1.1
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	2.9	1.0	0.7	1.3	1.6	0.7	0.6	0.7	1.7
Hearing difficulty/problems with background noise	1.1	1.8	2.8	-1.4	-1.6	-1.6	-0.7	-0.8	-1.7	-1.4	-1.1
Ever depressed for a whole week	1.1	1.4	3.4	1.3	0.9	1.2	1.3	-0.2	1.3	1.8	0.8
Multivitamins +/- minerals	1.0	1.3	2.6	-0.9	-0.7	-1.6	-1.0	-0.9	-1.2	-1.3	-1.4
Past tobacco smoking	1.0	1.8	4.2	1.7	0.8	1.3	1.9	0.2	1.2	-2.0	-0.4
Diabetes (self-reported)	1.0	1.5	3.0	-1.5	-1.7	-1.4	-1.3	-0.7	-1.6	0.2	-0.6
Depression (self-reported)	1.0	1.2	2.5	1.3	1.4	1.6	0.8	0.1	1.4	0.7	0.5
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.3	1.5	1.2	1.5	0.5	0.4	1.4	0.3	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.9	1.3	0.8	1.4	0.4	1.1	0.9	0.8	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.7	1.0	0.4	1.6	1.1	-0.4	1.1	1.3	1.3
Mood swings	1.0	1.8	3.5	1.7	1.3	1.6	1.9	0.3	1.6	0.6	1.0
Loneliness, isolation	1.0	1.4	2.1	-1.4	-1.3	-1.4	-0.8	-1.1	-1.2	-1.2	-0.5
Osteoporosis (self-reported)	1.0	1.2	6.1	0.5	0.8	0.9	-0.4	-0.7	0.8	2.5	0.8
Average weekly champagne plus white wine intake	1.0	1.4	3.3	1.0	0.8	1.8	0.7	0.2	1.6	1.4	0.9
Eye problems/disorders: Glaucoma	1.0	1.2	4.2	-0.6	-0.6	-0.8	-0.3	0.2	-0.8	-2.0	-1.8
Illnesses of father: High blood pressure	1.0	1.2	2.4	1.3	0.7	1.2	1.4	1.5	0.9	-0.2	1.0
Medication: Amlodipine	0.9	1.2	2.8	1.3	0.7	1.4	1.7	0.0	1.3	0.6	0.8
Whole body fat mass	0.9	3.6	8.0	2.0	2.8	2.1	2.2	-0.8	2.1	1.2	1.0
Hypertension (Self-reported)	0.9	2.5	7.1	1.0	1.2	1.3	0.9	0.2	1.3	2.5	2.7
Ever smoked	0.9	1.6	4.2	-1.3	-0.6	-1.3	-1.7	-0.2	-1.4	2.0	0.3
Cholesterol lowering medication	0.9	1.3	3.4	1.1	1.1	0.9	1.4	0.9	0.7	0.7	1.9
Alcohol drinker status: Previous	0.9	1.0	6.9	-0.3	-0.1	-0.2	-0.7	-0.4	-0.3	2.6	0.4
Type 2 Diabetes (T2D) (2012)	0.8	1.0	3.5	-0.1	-0.3	-0.6	0.2	-0.2	-0.4	-1.9	-1.9
Smoking Status	0.8	2.0	9.7	-0.6	-0.1	-0.5	-1.6	-1.3	0.0	3.1	1.2
Hair Pigment	0.8	21.8	42.5	5.7	5.7	5.0	6.5	-0.2	5.1	2.5	3.0
Systolic blood pressure, automated reading	0.8	2.3	4.8	1.7	1.8	1.0	2.2	0.1	1.1	1.6	1.6
Pack years adult smoking proportion	0.8	1.2	3.5	-1.5	-1.1	-0.6	-1.9	-0.1	-1.2	0.5	-0.9
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	2.0	1.2	0.5	1.1	0.9	-0.1	1.1	1.4	0.9
Number of live births	0.8	1.2	6.7	-0.3	0.1	0.1	-0.5	0.0	0.2	2.6	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.4	0.8	1.2	0.7	0.6	0.9	1.0	0.8	1.5
Medication: Lansoprazole	0.8	0.9	1.8	1.0	0.7	1.3	1.3	0.5	1.2	-0.6	0.2
Tense / ‘highly strung’	0.8	1.3	3.2	0.9	0.2	1.3	0.5	1.8	1.0	1.4	1.1
Glaucoma (self-reported)	0.8	1.0	4.6	0.1	-0.2	-0.2	0.5	-0.6	-0.3	-1.7	-2.1
Migraine (self-reported)	0.8	1.0	3.7	1.0	0.9	0.4	1.9	-1.1	0.6	0.6	-0.3
Arm fat percentage (left)	0.8	3.2	6.4	1.8	2.5	1.9	2.0	-1.1	1.7	1.6	1.0
Medication: Aspirin	0.8	1.1	3.5	0.6	0.7	1.2	0.8	1.1	0.9	1.9	0.7
Medication: Gliclazide	0.8	0.9	4.1	-0.7	-0.8	-0.1	-0.7	-0.9	-0.3	2.0	-0.6
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.3	1.2	1.2	0.4	1.5	-1.0	0.4	0.8	-0.3
Age started oral contraceptive pill	0.8	0.9	1.5	-1.1	-0.5	-1.2	-0.2	-0.7	-1.2	-1.1	-1.2
Impedance of whole body	0.8	4.1	9.5	1.9	1.9	1.9	1.9	1.2	1.8	2.0	3.1
Schizophrenia (2014)	0.7	1.6	3.6	1.3	1.6	1.2	1.9	-1.4	0.7	0.3	0.9
Respiratory disease	0.7	1.6	3.5	1.9	1.5	1.1	1.5	1.2	1.4	0.2	0.6
Medication: Metformin	0.7	0.9	3.5	-0.9	-1.1	-0.7	-0.3	-1.9	-0.8	0.2	-1.0
Diabetes (mother)	0.7	0.9	3.7	-0.9	-0.9	-0.1	-0.0	-1.2	-0.3	0.0	-1.9
Serious illness, injury or assault to yourself	0.7	0.8	3.0	0.4	0.7	0.7	1.0	-1.7	0.3	-1.1	-0.5
Allergy	0.7	1.7	3.2	-1.3	-1.2	-1.8	-1.1	-0.2	-1.7	-1.3	-1.1
Impedance of arm (right)	0.7	3.1	5.2	1.7	1.7	1.6	1.8	1.0	1.6	2.1	2.3
Arm fat percentage (right)	0.7	2.8	5.8	1.7	2.4	1.9	1.9	-1.1	1.7	1.5	0.8
Happiness	0.7	0.9	1.5	-1.0	-1.0	-1.1	-1.0	-1.2	-1.0	0.1	-0.3
Impedance of arm (left)	0.7	3.4	6.5	1.8	1.8	1.6	1.9	1.0	1.6	2.1	2.5
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.0	-0.6	-1.7	-0.7	-0.3	-0.1	-0.7	-1.6	-0.1
Qualifications: College or University degree	0.7	2.3	8.1	-0.8	-1.3	-1.3	-0.2	-1.0	-1.2	-2.0	-2.9
Neck or shoulder pain in last month	0.7	0.9	2.0	1.2	0.8	1.4	0.5	-1.3	0.9	0.8	0.4
Medication: Ibuprofen	0.7	0.8	2.1	0.5	1.1	0.4	0.4	1.5	0.8	-0.3	1.2
Medication: Omeprazole	0.7	0.9	2.6	-0.9	-1.1	-0.7	-0.3	-0.2	-0.9	-1.6	-0.9
Illnesses of father: Heart disease	0.7	1.0	2.8	0.8	0.7	1.0	1.0	-1.2	0.8	1.7	0.3
Smoking status: Previous	0.7	1.1	2.8	-1.3	-0.7	-0.7	-1.4	-0.3	-0.7	1.7	0.9
Number of self-reported non-cancer illnesses	0.7	1.2	4.4	0.5	0.7	0.6	-0.1	-0.1	0.4	2.1	1.9
Number of operations (self-reported)	0.7	1.0	3.0	0.8	0.3	1.0	0.8	-0.1	1.1	1.7	1.3
Irritability	0.7	1.1	3.0	-0.7	-1.5	-0.9	-0.8	-1.7	-0.8	-0.0	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	3.3	-0.5	-1.0	-0.6	0.0	0.3	-0.8	-1.8	-1.2
Blood Eosinophil Count	0.6	5.0	10.5	-2.5	-1.7	-3.2	-3.2	-1.7	-2.5	-0.5	0.2
Chronotype (morning person)	0.6	1.3	7.3	-0.5	-0.8	-0.3	-0.4	0.9	-0.5	-1.0	-2.7
Average weekly spirits intake	0.6	0.8	3.4	0.2	0.2	-0.0	-0.2	0.9	0.4	1.8	1.3
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.6	0.9	0.4	1.1	0.6	1.3	1.2	0.5	0.9
Impedance of leg (right)	0.6	3.1	10.6	1.5	1.1	1.6	1.4	1.1	1.4	1.8	3.2
Nervous feelings	0.6	1.0	4.5	-0.5	-1.2	-0.3	-0.4	0.8	-0.9	-0.4	-2.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	1.2	-1.1	-0.9	-0.9	-1.1	-0.8	-1.1	-0.8	-0.4
Length of working week for main job	0.6	0.6	1.8	0.4	-0.4	0.7	0.5	0.7	0.4	1.3	1.2
Blood clot in the leg (DVT)	0.6	0.7	1.6	-0.7	-0.9	-0.5	-1.3	1.0	-1.0	-0.4	-0.7
Exposure to tobacco smoke outside home	0.6	0.9	1.9	-1.0	-1.4	-0.6	-1.1	0.5	-0.8	0.5	-1.1
Wheeze or whistling in the chest in last year	0.6	1.0	3.6	-0.3	0.2	-0.4	-1.2	-1.9	-0.4	1.5	0.8
Heart disease (mother)	0.6	0.7	3.8	0.5	0.3	0.3	0.8	-0.9	0.4	2.0	0.0
Had major operations	0.6	0.8	3.2	0.5	0.4	0.9	-0.3	-0.6	0.7	1.8	0.9
Leg pain on walking	0.6	0.7	2.5	0.3	0.1	0.1	0.2	1.3	-0.1	1.6	1.2
Medication: Aspirin	0.6	0.8	2.7	0.5	0.4	1.0	0.9	1.1	0.6	1.6	0.4
Long-standing illness, disability or infirmity	0.6	1.0	1.7	1.0	0.9	1.3	1.2	-0.1	0.8	0.9	1.2
Diabetes diagnosed by doctor	0.6	1.0	1.8	-1.3	-1.3	-0.8	-1.0	-1.0	-1.1	0.7	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.2	0.8	0.6	0.9	1.1	0.8	1.1	0.4	0.4
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	5.0	0.1	0.1	0.8	0.2	0.0	0.4	1.1	2.2
Wears glasses or contact lenses	0.6	0.7	4.0	-0.3	-0.4	-0.0	-0.5	-2.0	0.1	0.9	-0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.4	-0.7	0.0	-1.2	-0.5	-1.1	-1.0	-1.2	-1.1
Alcohol drinker status: Never	0.6	0.7	1.8	0.8	1.4	1.1	0.7	0.1	0.8	0.2	0.9
Pain experienced in last month	0.6	0.9	1.9	-1.3	-0.7	-1.4	-0.9	0.4	-1.0	-1.1	-0.6
Pack years of smoking	0.6	0.9	2.4	-1.3	-0.9	-0.4	-1.5	0.0	-1.1	0.5	-0.9
Bipolar Disorder or Schizophrenia	0.5	1.2	2.2	1.4	1.3	0.8	1.5	-1.5	0.7	0.2	-0.3
Schizophrenia (2018)	0.5	1.1	3.3	1.0	1.4	0.6	0.8	-1.8	0.5	1.0	0.3
Irritable Bowel Disease (IBD)	0.5	1.1	2.0	1.1	1.1	1.4	1.3	0.8	1.2	0.2	0.9
Mean Putamen Volume	0.5	0.6	1.1	-0.9	-0.9	-0.6	-0.6	-0.8	-0.8	-0.3	-1.0
Fasting Glucose	0.5	0.6	1.3	0.5	0.8	0.7	0.9	0.8	0.7	1.1	-0.0
Primary Biliary Cirrhosis	0.5	0.7	1.5	-0.8	-0.5	-1.1	-0.8	-0.6	-0.7	-0.6	-1.2
Medication for hormone replacement therapy	0.5	0.6	1.9	0.6	0.6	0.7	0.5	-0.8	0.9	1.4	0.1
Age when periods started (menarche)	0.5	1.1	2.1	-1.4	-1.4	-1.1	-1.3	0.2	-1.1	-0.7	-0.3
High blood pressure	0.5	1.3	5.6	0.4	0.6	0.7	0.2	0.3	0.7	1.8	2.4
Impedance of leg (left)	0.5	2.5	8.7	1.3	1.0	1.5	1.4	0.8	1.2	1.4	3.0
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.6	0.6	0.3	0.9	0.8	0.0	0.8	1.9	0.5
Mouth/teeth dental problems	0.5	0.8	2.5	0.1	0.9	-0.8	0.1	-0.7	-0.5	-1.3	-1.6
Medication: Ramipril	0.5	0.7	1.7	0.1	-0.8	0.4	0.8	-1.3	-0.0	1.1	-0.9
Hip circumference	0.5	2.3	6.2	1.6	2.5	1.7	1.6	-0.1	1.5	1.3	0.5
Alcohol intake versus 10 years previously	0.5	0.7	2.8	-0.0	0.2	-0.6	0.0	0.4	-0.5	-1.7	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	2.2	0.3	-0.1	1.1	0.3	1.1	0.7	1.3	1.5
Illnesses of mother	0.5	0.6	1.6	-0.7	-0.3	-0.5	-1.3	1.2	-0.3	-0.9	0.2
Exposure to tobacco smoke at home	0.5	0.6	1.1	-0.9	-1.0	-0.0	-0.9	1.1	-0.5	-0.6	-0.7
Medication: Paracetamol	0.5	0.9	2.2	-0.8	-1.3	-0.6	-0.6	-0.1	-1.3	-0.0	-1.5
Emphysema/chronic bronchitis	0.5	0.5	0.7	0.7	0.8	0.6	0.8	0.8	0.4	0.8	0.8
Medication: Blood pressure	0.5	0.9	3.8	0.5	0.3	0.6	0.6	-1.3	0.5	1.9	0.7
Leg fat mass (right)	0.5	2.0	4.0	1.4	2.0	1.6	1.5	-1.2	1.5	0.8	0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.5	-0.2	-1.0	-0.6	0.0	-0.9	-0.8	0.2	-1.2
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.4	0.8	0.6	1.1	0.6	-0.5	0.6	1.2	0.5
Medication: Paracetamol	0.5	0.8	1.7	-0.9	-1.2	-0.6	-0.8	-0.5	-1.2	-0.4	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.5	-0.7	-0.8	-0.4	-1.2	1.2	-0.9	-0.2	-0.7
Bipolar Disorder (2018)	0.4	0.6	1.8	1.1	0.4	0.5	1.4	-0.1	0.4	-0.9	-0.8
Alzheimer’s Disease (in father)	0.4	0.4	1.1	-0.8	-0.5	-1.0	-1.0	0.5	-0.5	-0.1	0.2
Breast Cancer	0.4	0.9	1.8	-1.4	-1.2	-1.4	-0.7	-0.5	-0.9	-0.8	-0.6
Age at First Birth	0.4	0.6	1.7	0.7	0.5	-0.3	0.5	0.6	0.8	-0.8	1.3
Systolic Blood Pressure	0.4	2.0	3.3	1.7	1.5	1.2	1.8	0.5	1.1	1.6	1.4
Hypothyroidism (self reported)	0.4	1.0	2.4	0.5	0.0	1.6	0.3	1.3	1.1	-0.8	1.1
Medication: Co-codamol	0.4	0.4	0.9	0.8	0.3	0.7	0.9	-0.3	0.9	0.8	0.1
Average weekly fortified wine intake	0.4	0.5	3.0	0.2	0.7	-0.2	0.2	0.4	0.3	0.5	1.7
Relative age voice broke	0.4	0.6	3.5	0.5	0.7	0.7	0.1	0.1	0.6	1.9	0.4
Waist circumference	0.4	1.5	4.0	1.1	2.0	1.6	1.2	-0.8	1.3	0.3	0.3
Hair/balding pattern: Pattern 2	0.4	0.5	1.9	-0.7	-1.4	-0.6	-1.0	-0.6	-0.5	0.1	-0.1
Heart attack	0.4	0.6	1.2	0.8	0.9	1.1	0.8	0.2	0.8	0.7	0.1
Illnesses of siblings	0.4	0.5	2.2	-0.0	0.0	-0.2	0.1	0.2	0.2	-1.5	-1.3
Trunk fat-free mass	0.4	2.5	7.8	-1.4	-1.2	-1.1	-1.2	-0.7	-1.0	-2.2	-2.8
Time employed in main current job	0.4	0.5	1.0	-0.9	-0.7	-1.0	-0.4	-0.1	-1.0	-0.6	-0.6
Worrier / anxious feelings	0.4	0.7	2.7	0.1	-0.8	-0.4	0.7	1.6	-0.8	0.8	0.7
Hair/balding pattern: Pattern 3	0.4	0.6	2.1	-0.1	0.0	-0.8	-0.3	-1.4	-0.8	0.5	-1.0
Mouth/teeth dental problems: Dentures	0.4	0.7	2.4	-0.1	-0.2	0.5	-0.3	1.4	0.5	1.6	0.6
Medication: Cholesterol lowering	0.4	0.6	2.5	0.1	-0.1	0.7	0.6	-0.7	0.6	1.6	0.7
Arm fat mass (right)	0.4	1.7	3.9	1.3	2.0	1.5	1.5	-0.9	1.4	0.7	0.2
Trunk predicted mass	0.4	2.6	7.8	-1.4	-1.3	-1.1	-1.2	-0.7	-1.1	-2.2	-2.8
Peak expiratory flow (PEF)	0.4	1.0	2.2	-0.8	-1.5	-0.9	-1.1	0.6	-0.6	-0.7	-1.3
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.5	0.5	0.6	0.7	0.5	0.3	0.7	0.2	1.2
High blood pressure (siblings)	0.4	0.6	2.2	-0.2	-0.5	-0.0	-0.4	0.4	-0.5	1.2	1.5
Comparative body size at age 10	0.4	1.2	5.7	-0.6	-0.7	-0.9	-0.9	-0.1	-0.5	-1.0	-2.4
Supplements: Vitamin C	0.4	0.5	1.0	0.6	0.8	0.6	0.3	-0.9	1.0	-0.6	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.6	-1.1	-1.3	-0.9	-0.7	1.0	-0.7	-0.9	-0.3
Arm fat mass (left)	0.4	1.8	4.3	1.4	2.1	1.4	1.6	-0.9	1.4	0.7	0.2
Hearing aid user	0.4	0.4	2.0	0.3	0.3	0.5	0.3	-0.8	-0.1	-0.6	1.4
High cholesterol (Self-reported)	0.4	0.8	1.6	0.9	0.4	1.0	1.0	-0.8	0.9	0.3	1.3
Medication: Atorvastatin	0.4	0.4	2.8	0.1	0.5	0.3	0.3	-0.0	0.0	1.7	0.6
Diastolic blood pressure, automated reading	0.4	1.2	3.3	0.9	0.9	0.3	1.3	-0.2	0.6	1.6	1.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.1	0.8	0.9	1.1	0.8	0.2	0.7	0.7	-0.1
Leg fat mass (left)	0.4	1.7	3.5	1.3	1.9	1.5	1.4	-1.2	1.4	0.6	0.7
Schizophrenia vs Biploar Disorder	0.3	0.4	1.0	0.2	0.4	0.7	0.3	-0.3	0.5	1.0	0.9
Alzheimer’s Disease (in mother)	0.3	0.3	1.4	0.3	0.2	0.1	-0.3	-0.3	-0.1	0.9	1.2
Alzheimer’s Disease (including proxy)	0.3	0.4	1.3	-0.1	-0.1	-0.5	-0.8	0.3	-0.2	0.8	1.1
Prostate Cancer	0.3	0.4	0.9	-0.2	-0.8	-0.5	-0.2	1.0	-0.5	-0.8	-0.8
Crohns Disease (2012)	0.3	0.4	1.3	-0.5	-0.5	-0.1	-1.0	0.8	-0.3	-1.2	-0.0
HbA1C	0.3	0.4	0.7	-0.4	-0.3	-0.8	-0.8	-0.5	-0.3	-0.4	-0.9
Rheumatoid Arthritis	0.3	0.4	1.1	-0.6	-1.1	-0.6	-0.4	0.0	-0.5	-0.9	-0.6
Triglycerides	0.3	0.5	1.9	0.7	0.9	0.2	0.8	0.4	0.5	-0.2	-1.4
Blood Red Count	0.3	2.5	4.7	2.2	1.4	0.9	1.5	1.6	1.4	1.1	2.1
Blood White Count	0.3	2.0	5.5	-2.1	-1.3	-0.8	-2.3	-1.1	-1.4	-0.2	0.7
Lung FEV1/FVC ratio	0.3	1.5	3.8	1.7	0.6	0.4	1.9	1.3	0.9	-0.1	1.5
Number of treatments/medications taken	0.3	0.5	2.4	0.5	0.3	0.8	0.4	-0.4	0.5	1.6	0.3
Sensitivity / hurt feelings	0.3	0.4	1.1	-0.6	-0.5	-0.8	-0.5	-0.4	-1.1	-0.3	-0.8
Relative age of first facial hair	0.3	0.6	2.4	-0.8	-0.1	-0.3	-1.1	-0.2	-0.4	1.6	0.5
Diabetes (father)	0.3	0.3	1.4	0.2	0.6	0.1	0.1	-0.5	-0.3	-0.7	-1.2
Townsend deprivation index at recruitment	0.3	0.4	1.4	0.0	0.1	1.2	0.2	0.2	0.8	1.0	-0.0
Current tobacco smoking	0.3	0.5	2.8	-0.2	-0.2	-0.4	-1.0	-0.4	-0.0	1.7	-0.1
Maternal smoking around birth	0.3	0.4	1.5	-0.9	-0.5	-0.5	-1.2	0.3	-0.7	-0.3	0.2
Qualifications: CSEs or equivalent	0.3	0.4	0.8	-0.5	-0.1	0.0	-0.8	0.9	-0.1	-0.9	0.8
Stomach or abdominal pain in last month	0.3	0.4	1.0	-1.0	-0.7	-0.2	-0.9	0.1	-0.4	-0.1	-1.0
Medication: Levothyroxine sodium	0.3	0.5	1.3	-0.6	-0.8	-0.3	-0.8	0.9	-0.6	-1.1	0.3
Body mass index (BMI)	0.3	1.4	3.2	1.2	1.8	1.3	1.2	-1.0	1.2	0.7	0.2
Alcohol usually taken with meals	0.3	0.5	2.8	0.1	1.2	-0.2	-0.0	-0.1	-0.1	-1.7	0.1
Had other major operations	0.3	0.4	0.8	0.9	0.4	0.7	0.9	0.3	0.7	0.2	0.6
Pain all over the body in last month	0.3	0.4	1.4	0.4	0.5	0.2	0.0	1.0	0.4	0.1	1.2
Medication: Simvastatin	0.3	0.4	1.0	0.5	0.0	0.6	0.7	0.4	0.8	0.4	1.0
Loud music exposure frequency	0.3	0.3	1.3	-0.4	-0.9	-0.0	-0.3	0.1	-0.1	0.1	-1.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.6	-0.5	-0.3	-0.8	-0.8	0.9	-0.7	-1.2	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.1	-0.3	-0.2	0.0	-0.8	-1.0	-0.0	0.3	0.9
Number of children fathered	0.3	0.4	0.6	-0.6	-0.7	-0.8	-0.7	-0.6	-0.5	-0.0	0.5
Family relationship satisfaction	0.3	0.4	1.1	-0.4	-0.2	-0.4	-0.7	-1.0	0.0	1.0	-0.4
Illnesses of siblings: Diabetes	0.3	0.4	1.0	-0.8	-0.6	-0.2	-0.9	-0.5	-0.1	-1.0	-0.2
Whole body fat-free mass	0.3	1.7	6.6	-0.9	-0.6	-0.7	-0.7	-0.9	-0.5	-1.9	-2.6
Eye problems/disorders: Cataract	0.3	0.3	0.9	-0.5	-0.4	-0.5	-0.5	0.2	-0.7	-1.0	-0.3
Back pain experienced in last month	0.3	0.5	1.4	0.5	0.5	0.8	0.4	0.7	0.6	0.4	1.2
Illnesses of father: None of the above (group 1)	0.3	0.4	0.9	0.6	0.6	0.6	0.5	0.3	0.7	1.0	0.3
Smoking status: Current	0.3	0.5	2.9	-0.3	-0.2	-0.5	-1.0	-0.3	-0.2	1.7	-0.1
Whole body water mass	0.3	1.7	6.3	-1.0	-0.6	-0.7	-0.7	-0.7	-0.6	-2.0	-2.5
Commuting to job workplace: Public transport	0.3	0.4	1.4	0.0	0.1	0.2	0.3	-0.9	0.1	-1.2	-0.8
Unable to work because of sickness or disability	0.3	0.4	1.4	-0.9	-0.5	0.2	-1.2	-0.3	-0.4	-0.1	-0.6
Arm predicted mass (left)	0.3	1.5	4.6	-1.0	-0.6	-0.6	-0.9	-0.5	-0.5	-2.0	-2.1
Depressed Affect (Nagel 2018)	0.2	0.5	1.4	0.9	0.1	0.4	1.2	0.7	0.6	0.3	0.7
Worry (Nagel 2018)	0.2	0.5	2.1	0.6	-0.3	0.4	0.9	1.5	0.0	0.3	0.6
Major Depression (MDD)	0.2	0.2	0.8	0.9	0.0	0.1	0.6	-0.5	0.4	-0.2	-0.2
BMI	0.2	1.3	4.6	1.3	2.1	1.1	1.1	-0.7	1.3	0.1	0.1
Allergy or Eczema	0.2	0.4	1.6	-0.7	-0.5	-0.3	-0.7	-1.2	-0.5	-0.1	-0.2
Tanning	0.2	2.1	4.9	-1.3	-1.4	-1.7	-2.2	1.3	-1.6	0.5	-0.7
Hearing difficulty/problems: Yes	0.2	0.3	1.3	0.6	0.6	0.2	1.1	-0.2	-0.1	-0.6	0.1
Supplements: Zinc	0.2	0.2	0.4	0.6	0.3	0.5	0.1	0.1	0.6	-0.1	0.6
Fed-up feelings	0.2	0.5	2.3	0.3	0.1	0.4	0.3	1.5	0.4	0.5	0.7
Taking other prescription medications	0.2	0.3	0.8	0.4	0.2	0.5	0.1	-0.7	0.2	0.9	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.3	0.8	0.3	0.4	0.9	0.3	-0.6	0.8	0.4	0.6
High blood pressure (mother)	0.2	0.3	0.9	0.3	0.0	0.3	0.9	-0.9	0.3	0.7	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.3	-0.6	-0.5	-1.0	-1.2	0.0	-0.7	-0.6	0.1
Neuroticism score	0.2	0.5	1.7	-0.5	-1.3	-0.8	-0.5	0.1	-0.9	0.2	-0.2
Weight	0.2	1.1	2.5	0.9	1.6	1.3	1.2	-0.8	1.2	-0.2	-0.4
Falls in the last year	0.2	0.3	0.7	-0.3	-0.9	-0.1	-0.3	0.3	-0.6	0.8	0.7
Pulse rate	0.2	0.3	1.1	0.0	0.0	0.0	0.8	-0.3	0.1	-1.1	-0.9
Noisy workplace	0.2	0.2	0.8	-0.4	-0.7	-0.3	0.2	-0.1	-0.9	-0.3	-0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.9	-0.4	-0.6	0.4	-0.3	0.9	-0.1	-0.9	0.8
Arm fat-free mass (right)	0.2	1.1	4.0	-0.7	-0.3	-0.5	-0.6	-0.7	-0.3	-2.0	-1.8
Number of full brothers	0.2	0.3	0.9	-0.3	0.4	-0.3	-0.4	-0.9	-0.2	-0.4	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.7	0.1	0.5	0.2	0.3	0.6	-0.0	0.5	0.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	0.1	-0.1	0.8	0.3	-0.5	0.5	-0.2	0.6
Medication for pain relief, constipation, heartburn	0.2	0.4	1.3	-0.4	-0.2	-0.7	-0.8	-0.8	-0.2	-1.2	-0.4
Arm predicted mass (right)	0.2	1.1	4.5	-0.5	-0.2	-0.4	-0.4	-0.6	-0.3	-2.1	-1.9
Comparative height size at age 10	0.2	1.1	2.0	1.0	1.4	0.9	0.8	1.0	1.4	-1.2	0.1
Chest pain or discomfort	0.2	0.3	1.9	0.1	-0.3	0.2	-0.1	-1.4	-0.1	0.3	0.6
Age at last live birth	0.2	0.3	1.7	0.0	-0.3	-0.3	0.1	-0.2	-0.2	-1.3	-0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.5	0.2	0.2	-0.4	0.4	1.2	0.0	-0.4	-0.1
Knee pain experienced in last month	0.2	0.4	1.6	0.2	0.1	0.4	0.2	-1.3	-0.1	1.0	0.0
Leg fat-free mass (right)	0.2	0.9	4.7	-0.3	0.2	-0.2	-0.1	-0.7	0.0	-1.4	-2.2
Commuting to job workplace: Walk	0.2	0.2	0.6	0.4	0.4	-0.3	0.6	0.2	0.2	-0.8	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.4	-0.2	-0.1	-0.2	0.7	-0.8	0.1	-0.3
Leg predicted mass (right)	0.2	1.0	5.0	-0.3	0.1	-0.2	-0.1	-0.7	0.0	-1.5	-2.2
Ever taken oral contraceptive pill	0.2	0.2	0.9	-0.2	-0.1	0.3	-0.6	0.1	0.2	0.9	0.6
Basal metabolic rate	0.2	1.0	4.5	-0.4	-0.1	-0.2	-0.2	-0.8	-0.1	-1.5	-2.1
Arm fat-free mass (left)	0.2	1.2	4.0	-0.9	-0.5	-0.6	-0.7	-0.3	-0.5	-2.0	-1.9
Myopia	0.2	0.3	0.9	1.0	0.2	0.5	0.5	0.2	0.5	-0.6	-0.2
Heart disease (siblings)	0.2	0.3	0.6	0.7	0.6	0.7	0.4	0.4	0.3	0.8	0.2
Neuroticism (Nagel 2018)	0.1	0.3	0.8	0.5	-0.4	-0.3	0.9	0.8	-0.4	0.5	0.3
Crohns Disease (2017)	0.1	0.2	0.8	0.2	0.1	0.6	-0.2	0.9	0.5	-0.5	0.2
Ovarian Cancer	0.1	0.2	0.6	0.5	0.6	0.1	0.8	0.1	0.5	-0.0	0.2
Lupus	0.1	0.2	0.4	-0.1	0.6	-0.1	-0.3	0.4	0.3	-0.5	-0.5
Heel T-Score	0.1	0.8	2.0	-0.9	-0.3	-1.4	-1.4	-0.7	-0.5	0.6	0.9
Waist Hip Ratio (WHR)	0.1	0.5	2.4	-0.5	-0.4	-0.3	-0.9	-0.1	-0.4	-1.5	-0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	-0.3	-0.5	-0.2	0.1	-0.8	-0.4	0.4	-0.2
Vitamin and mineral supplements	0.1	0.2	0.6	-0.1	-0.5	0.2	0.3	0.8	-0.2	0.6	0.0
Severe depression (siblings)	0.1	0.1	0.2	-0.0	-0.3	0.3	-0.4	0.2	0.2	-0.2	0.3
Leg fat-free mass (left)	0.1	0.7	3.5	-0.3	0.2	-0.2	-0.1	-0.8	0.1	-1.2	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.0	-0.2	0.4	0.2	-0.5	0.2	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.7	-0.2	-0.5	-0.9	-0.5	-0.0	-0.7	-0.5	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.3	0.6	0.3	0.4	0.0	0.3	-0.1	-0.1
Chronic bronchitis/emphysema (father)	0.1	0.1	0.3	-0.2	-0.4	0.5	0.0	-0.4	0.4	-0.2	-0.1
Leg predicted mass (left)	0.1	0.7	3.2	-0.2	0.3	-0.1	-0.0	-0.8	0.1	-1.2	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.1	-0.7	-0.2	-0.0	0.1	-0.1	-0.1	-0.4
Standing height	0.1	0.8	3.6	-0.4	-0.3	-0.1	-0.0	0.7	0.0	-1.9	-1.3
Shortness of breath walking on level ground	0.1	0.1	0.4	0.4	0.4	0.3	0.4	0.3	-0.1	0.0	0.6
Eye problems/disorders: None of the above	0.1	0.2	0.4	0.4	0.0	0.5	0.4	-0.2	0.4	0.6	-0.3
Medication: Seretide 50 evohaler	0.1	0.1	0.2	0.3	0.2	0.4	0.4	-0.4	0.5	0.4	-0.4
Pulse rate, automated reading	0.1	0.2	0.8	-0.4	-0.3	0.1	0.0	0.8	0.1	-0.9	-0.3
Alcohol intake frequency.	0.1	0.2	0.8	-0.0	0.5	0.2	-0.0	-0.2	0.1	-0.9	-0.7
Suffer from ‘nerves’	0.1	0.2	0.8	-0.2	-0.1	-0.1	-0.7	0.9	-0.4	-0.0	-0.2
Average weekly red wine intake	0.1	0.2	0.7	-0.3	-0.3	-0.6	-0.0	-0.3	-0.4	0.8	-0.2
Friendships satisfaction	0.1	0.1	0.4	0.6	0.5	0.1	0.3	-0.4	0.2	0.4	0.2
Miserableness	0.1	0.1	0.4	0.2	-0.1	-0.2	0.2	0.6	-0.0	0.3	0.5
Guilty feelings	0.1	0.1	0.5	-0.2	-0.4	0.2	0.4	0.1	-0.5	0.0	-0.7
Financial situation satisfaction	0.1	0.2	0.6	-0.6	-0.4	0.3	-0.8	-0.1	-0.1	0.3	-0.3
Fractured/broken bones in last 5 years	0.1	0.2	0.7	-0.3	-0.5	-0.1	-0.3	0.8	0.0	-0.2	0.4
Supplements: Calcium	0.1	0.2	0.5	0.4	0.4	-0.0	0.2	0.3	0.4	-0.7	0.4
Height	0.0	0.5	1.9	-0.6	-0.5	-0.2	-0.6	0.1	-0.6	-1.4	-0.9
Neuroticism	0.0	0.1	0.2	0.3	-0.2	-0.0	0.2	0.4	0.0	0.3	0.4
Sitting height	0.0	0.2	1.0	-0.2	0.0	-0.1	-0.1	0.6	0.3	-1.0	-0.2

Hub : Genes

PLXNA1

Models

Trait associations