[Hub]/) : Traits : Hair Pigment : ← →

chr3:140,074,782-142,640,214

Best TWAS P=5.46e-119 · Best GWAS P=6.2e-112 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SPSB4 0.03 0.01 bslmm 414 0.01 7.3e-03 -1.38 -6.6 3.5e-11 -0.27 0.16 0.09 FALSE
2 GTEx Adipose Subcutaneous ZBTB38 0.08 0.04 lasso 4 0.03 8.1e-04 22.34 23.2 5.5e-119 0.98 0.01 0.99 TRUE
3 GTEx Artery Tibial GK5 0.16 0.03 lasso 7 0.04 5.5e-04 5.43 6.7 1.9e-11 0.10 0.13 0.66 FALSE
4 GTEx Cells Transformed fibroblasts ATP1B3 0.12 0.12 lasso 3 0.08 1.9e-06 6.59 7.2 4.0e-13 0.07 0.98 0.00 TRUE
5 GTEx Muscle Skeletal ATP1B3 0.11 0.02 enet 24 0.03 1.1e-03 -0.69 -6.4 1.4e-10 -0.23 0.15 0.04 FALSE
6 GTEx Testis ZBTB38 0.14 0.06 lasso 8 0.05 2.8e-03 13.23 16.4 2.7e-60 0.59 0.22 0.63 FALSE
7 GTEx Thyroid ZBTB38 0.11 0.03 enet 32 0.04 2.9e-04 17.90 15.6 8.9e-55 0.61 0.07 0.92 FALSE
8 NTR Blood ZBTB38 0.03 0.01 lasso 3 0.01 2.2e-05 22.48 19.7 3.5e-86 0.87 0.01 0.99 FALSE
9 YFS Blood ATP1B3 0.05 0.02 enet 22 0.03 8.3e-10 8.42 6.4 1.5e-10 0.07 1.00 0.00 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma TFDP2 0.13 0.02 blup 97 0.05 1.2e-03 8.90 7.7 1.6e-14 0.10 0.02 0.78 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma ATP1B3 0.05 0.03 lasso 5 0.04 4.5e-05 5.30 6.7 1.9e-11 -0.01 0.13 0.44 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma ZBTB38 0.04 0.03 lasso 3 0.04 3.0e-03 15.02 16.9 2.2e-64 0.59 0.05 0.36 FALSE