Hub : Genes

GK5

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1560	0.0540	2.0e-04	0.060	NA	0.060	NA	0.055	3.1e-04	NA	3.1e-04	NA	5.5e-04
2	GTEx	Artery Tibial	0.1563	0.0544	8.4e-05	0.031	NA	0.031	NA	0.038	1.8e-03	NA	1.6e-03	NA	5.4e-04
3	GTEx	Breast Mammary Tissue	0.2030	0.0800	2.7e-03	0.015	NA	0.028	NA	0.017	5.6e-02	NA	1.4e-02	NA	4.5e-02
4	GTEx	Breast Mammary Tissue (Female)	0.0139	0.0492	4.1e-01	0.046	NA	-0.003	NA	0.027	1.7e-02	NA	4.0e-01	NA	5.3e-02
5	GTEx	Cells Transformed fibroblasts	0.1780	0.0520	1.1e-06	0.095	NA	0.090	NA	0.095	1.4e-07	NA	2.7e-07	NA	1.4e-07
6	GTEx	Nerve Tibial	0.2028	0.0626	1.8e-04	0.012	NA	0.012	NA	0.067	4.2e-02	NA	4.7e-02	NA	1.6e-05
7	GTEx	Thyroid	0.0480	0.0250	6.3e-03	0.059	NA	0.009	NA	0.036	2.5e-05	NA	6.6e-02	NA	9.4e-04
8	METSIM	Adipose	0.0234	0.0136	1.9e-02	-0.001	0.002	-0.001	0.002	-0.001	4.6e-01	1.5e-01	5.1e-01	1.4e-01	6.3e-01
9	YFS	Blood	0.1220	0.0295	3.0e-13	0.046	0.051	0.058	0.071	0.051	9.0e-15	2.9e-16	2.8e-18	2.7e-22	2.3e-16
10	TCGA	Breast Invasive Carcinoma	0.0216	0.0122	4.8e-03	-0.001	0.006	0.002	NA	-0.001	5.4e-01	1.5e-02	1.1e-01	NA	5.0e-01
11	TCGA	Cervical Squamous Cell Carcinoma	0.0990	0.0510	4.1e-03	0.019	0.025	0.014	NA	0.003	3.7e-02	2.1e-02	6.5e-02	NA	2.2e-01
12	TCGA	Prostate Adenocarcinoma	0.0786	0.0393	9.8e-05	0.009	0.048	0.054	NA	0.037	3.8e-02	8.1e-06	2.3e-06	NA	9.0e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	1.2	1.9	5.8	2.4	-1.3	0.5	-1.0	1.2	1.2	1.8	0.0	-1.2	2.0	1.4	0.5
Bipolar Disorder or Schizophrenia	0.3	0.7	2.0	1.4	-0.6	-0.8	-0.7	1.1	0.1	0.9	-0.4	-1.4	0.3	-0.1	0.8
Depressed Affect (Nagel 2018)	0.2	0.5	1.3	-0.6	-1.0	1.0	-1.1	-0.3	-1.1	0.0	0.4	-0.2	-0.1	0.5	0.5
Depression (Nagel 2018)	0.1	0.2	0.5	0.5	0.1	0.6	0.7	0.4	-0.3	0.3	0.4	0.0	-0.3	-0.3	0.1
Intelligence (Savage-Jansen 2018)	1.0	3.0	12.4	0.5	-0.3	-0.3	3.1	-0.7	0.3	-0.9	1.6	-3.5	1.9	0.5	-2.5
Neuroticism (Nagel 2018)	0.2	0.4	2.6	0.1	-1.6	0.2	-0.8	-0.6	-0.8	0.2	0.7	-0.3	0.1	0.3	-0.6
Schizophrenia (2018)	0.4	0.9	5.3	-0.2	0.2	-2.3	-0.2	0.5	-0.9	-0.3	-0.5	-0.8	-1.2	-1.3	0.7
Schizophrenia vs Biploar Disorder	0.9	1.3	4.8	-1.9	0.8	-0.7	0.4	-0.8	-0.3	-0.5	-0.2	-0.1	-2.2	-2.1	-0.1
Worry (Nagel 2018)	0.2	0.5	1.9	1.1	-0.2	-0.5	1.1	0.7	-0.7	1.4	-0.0	-0.2	-0.2	-0.4	0.5
Alzheimer’s Disease (in mother)	0.8	1.0	5.6	0.3	-1.3	-0.6	-2.4	-1.2	-0.4	-0.5	-0.5	0.2	0.6	1.1	0.2
Alzheimer’s Disease (in father)	2.4	2.6	6.6	2.2	1.3	-0.7	0.9	1.5	-0.3	2.1	-2.3	-0.7	-2.0	-2.6	0.2
Alzheimer’s Disease (including proxy)	0.7	1.1	4.1	1.4	-0.6	-0.6	-2.0	-0.1	-0.6	1.0	-1.9	-0.3	-0.2	-0.0	1.0
Crohns Disease (2017)	0.4	0.9	4.3	0.4	-0.0	-2.1	-0.3	-0.2	-0.9	-0.4	-0.4	0.9	-1.4	-1.2	-1.0
Irritable Bowel Disease (IBD)	0.9	2.2	11.1	1.4	2.4	-0.7	0.5	1.8	0.9	1.3	0.6	3.3	-0.6	-0.4	-0.1
Ulcerative Colitis (UC)	2.5	4.8	14.8	1.7	3.9	1.2	1.2	2.9	2.2	2.1	1.6	3.8	0.7	0.8	0.8
Major Depression (MDD)	2.0	2.4	11.1	-1.1	0.4	3.3	0.6	-1.0	1.4	-1.6	1.8	0.5	1.3	1.4	-1.9
Reaction Time	0.6	1.1	4.5	-0.0	0.2	-0.1	-1.4	1.4	0.1	0.8	-2.1	1.0	-1.4	-0.7	0.8
Verbal and Numeric Reasoning (VNR)	0.7	1.6	5.7	0.6	-1.0	0.3	1.6	-0.7	0.4	-0.6	1.5	-2.4	1.3	0.2	-2.2
Breast Cancer	0.5	1.1	3.6	-1.9	1.2	0.7	1.9	-0.9	-0.4	-1.3	-0.3	-0.5	-0.7	-0.3	1.0
Ovarian Cancer	0.3	0.3	0.8	0.9	-0.6	0.8	0.1	0.6	-0.0	0.4	0.6	0.9	0.5	0.6	0.3
Prostate Cancer	1.1	1.5	4.6	-1.2	-0.6	-0.9	-1.2	-0.6	-1.8	-1.0	-2.1	1.1	-0.6	0.5	1.8
Age at First Birth	1.1	1.6	5.7	1.2	1.2	0.0	1.6	2.0	-0.7	1.4	-1.3	-0.2	0.3	0.3	2.4
Bipolar Disorder (2011)	0.8	0.8	3.4	1.5	-1.8	-0.5	-1.3	0.1	0.0	1.0	0.2	-1.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.5	0.7	3.9	0.5	-0.0	2.0	0.1	0.3	1.0	0.5	0.5	-0.2	-0.7	-1.1	-0.9
Coronary Artery Disease (CAD)	0.3	0.4	1.5	-0.0	0.1	1.2	-1.1	-0.6	0.0	0.2	-1.1	0.4	-0.1	0.5	0.6
Crohns Disease (2012)	0.7	1.1	2.7	-1.0	-0.9	-1.5	-0.6	-1.2	-1.4	-1.6	-0.8	0.0	-1.1	-0.6	-0.3
Mean Putamen Volume	2.2	2.5	7.8	-1.0	-2.7	-1.0	-2.8	-0.4	-2.1	-0.1	-1.1	0.2	-2.2	-1.5	0.5
Fasting Glucose	0.4	0.4	1.5	-0.1	0.7	0.6	0.2	1.2	0.6	0.2	0.4	-0.6	-0.9	-1.0	-0.2
HbA1C	0.7	0.8	3.6	-1.9	-0.3	-1.0	-0.0	-1.0	-0.1	-0.6	-0.4	1.5	-0.5	0.3	0.6
HDL Cholesterol	0.6	1.0	3.3	0.3	1.3	1.1	1.8	0.8	0.6	0.8	0.7	-1.1	-0.2	-1.2	-0.9
LDL Cholesterol	0.6	0.9	3.0	0.7	1.5	-1.1	0.3	1.7	-0.0	1.3	-0.8	0.7	-0.4	-0.2	0.7
Lupus	0.7	1.1	4.0	0.0	1.0	0.1	0.9	-1.1	0.6	-1.0	1.2	-2.0	1.6	0.8	-0.5
Neuroticism (2016)	1.0	1.4	7.7	-0.1	-2.8	-0.4	-1.0	-1.5	-1.2	-0.5	0.2	-0.5	0.2	-0.2	-2.0
Primary Biliary Cirrhosis	1.4	2.0	7.0	-0.5	-2.3	-0.1	-2.6	-1.3	-1.3	-0.7	-0.7	0.1	-1.4	-1.4	-1.7
Rheumatoid Arthritis	1.1	1.5	4.7	1.9	1.3	0.5	2.2	1.0	1.5	1.0	0.8	-0.0	-0.6	-1.2	-1.3
Schizophrenia (2014)	0.1	0.3	0.9	0.4	-0.4	-1.0	-0.8	0.1	-0.5	-0.1	-0.2	-0.2	-0.6	-0.6	0.7
Triglycerides	1.2	2.0	6.2	0.2	0.5	-0.3	-1.9	1.3	0.1	1.8	-2.4	1.5	0.0	1.0	2.5
Type 2 Diabetes (T2D) (2012)	1.1	1.2	3.7	0.3	1.9	-0.1	-0.3	1.4	1.5	0.9	0.3	0.2	-1.3	-1.9	-0.6
Ulcerative Colitis	2.9	4.2	15.0	1.3	2.5	3.9	1.1	1.7	2.2	0.9	1.5	3.8	0.5	0.9	0.3
Blood Eosinophil Count	0.5	4.0	10.4	1.3	2.0	-0.3	-1.5	2.7	0.8	2.4	-2.5	3.2	-1.8	-0.9	2.4
Blood Platelet Count	0.1	1.4	4.1	-1.4	2.0	-1.0	1.7	1.0	0.8	-0.2	0.7	-1.2	-0.2	-1.3	-1.0
Blood Red Count	2.2	20.9	89.7	-3.3	-0.7	1.7	0.4	-5.4	2.1	-6.8	9.5	3.6	1.7	1.7	-7.0
Blood White Count	0.7	5.2	19.3	3.9	1.5	0.2	1.2	4.3	0.5	4.4	-0.7	0.6	0.6	-0.4	2.1
Heel T-Score	0.4	3.1	15.2	-1.0	-1.3	-1.0	-1.4	0.2	-2.3	0.7	-3.9	2.4	-0.6	0.4	2.1
BMI	0.8	4.8	14.5	-3.8	-1.0	-1.9	-3.4	-1.2	-1.6	-0.8	-3.4	-1.0	-1.8	-0.8	2.4
Height	0.3	5.9	14.7	2.1	2.5	-0.8	3.8	2.5	-0.3	0.0	3.6	-2.7	3.7	2.0	-0.1
Waist Hip Ratio (WHR)	0.6	2.8	12.2	0.0	0.0	-1.9	0.5	-0.2	-3.5	0.1	-1.4	-0.0	-2.8	-2.8	-0.1
Systolic Blood Pressure	0.6	3.0	13.6	-1.0	-0.7	-1.4	-1.9	-0.7	-0.7	0.2	-2.1	1.2	-3.7	-2.6	1.4
Smoking Status	0.8	1.9	6.0	-0.3	-1.3	0.9	-0.3	-1.7	0.4	-2.1	1.9	1.5	0.6	0.9	-2.4
Allergy or Eczema	0.5	1.4	3.2	1.2	-0.1	-0.6	0.0	1.5	-1.5	1.4	-1.6	0.8	-1.5	-1.8	-0.6
Cardiovascular Disease	0.1	0.4	2.2	-1.5	-0.1	-0.2	-0.6	-0.4	-1.1	-1.1	0.1	0.1	-0.2	-0.0	-0.1
Hypothyroidism (self reported)	1.5	3.5	14.1	-1.8	-3.8	-2.2	-3.1	-1.7	-1.6	-1.1	-1.1	0.3	-1.0	-0.4	-0.6
Respiratory disease	0.3	0.7	2.1	-0.6	-0.5	-1.4	0.0	0.2	-1.5	-0.5	-1.3	0.9	0.2	0.5	-0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.7	1.2	-0.3	1.0	0.1	1.0	1.1	1.3	0.9	0.6	0.8	0.8	-0.1
Lung FEV1/FVC ratio	0.7	3.4	15.4	0.7	0.8	0.9	3.9	0.4	1.2	-0.4	3.3	-0.2	0.1	-1.1	-3.0
Lung FVC	0.3	1.4	4.5	-0.2	-1.1	-0.8	-1.5	-1.0	-0.0	0.2	-0.7	1.4	-2.1	-1.9	-0.8
Neuroticism	0.5	1.2	3.5	-0.5	-1.8	0.9	-1.9	-0.8	-0.4	-0.1	1.0	1.2	1.0	1.5	-0.7
Chronotype (morning person)	0.8	2.0	5.6	-1.2	-0.9	1.4	-2.0	-0.8	1.7	-1.2	0.6	1.3	-1.1	-1.1	-2.4
Hair Pigment	0.2	6.0	45.0	-0.7	6.7	1.6	2.1	1.9	2.6	0.1	1.2	1.3	1.5	1.8	0.1
Tanning	0.1	1.7	6.1	-0.6	-1.6	-1.4	-2.5	0.0	-1.4	1.0	-1.9	-0.4	0.1	0.4	1.5
Hand grip strength (left)	0.3	0.8	2.5	1.0	1.6	-0.1	1.6	0.2	0.0	0.2	0.3	1.1	0.2	-0.0	-1.3
Number of treatments/medications taken	0.5	0.9	3.5	-0.6	-0.5	-0.3	-0.6	0.3	-1.3	0.2	-1.3	0.2	-1.9	-1.3	1.0
Average weekly spirits intake	0.9	1.2	4.1	0.5	1.4	1.4	1.2	1.4	0.9	0.5	0.8	-2.0	0.1	-0.9	0.2
Sensitivity / hurt feelings	0.6	1.0	5.7	0.1	-0.1	0.6	-0.1	-0.1	1.0	-0.1	1.9	-0.7	0.8	0.3	-2.4
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.3	-1.0	-0.1	-0.7	1.1	0.2	-0.7	-0.5	-0.5	0.7	-1.5	-1.3	0.1
Hearing difficulty/problems: Yes	0.6	1.0	2.2	-0.8	-1.4	1.4	-1.5	-0.5	-0.2	-0.3	-0.3	1.4	0.8	1.4	0.2
Relative age of first facial hair	0.3	0.7	2.5	1.6	-0.1	0.7	0.0	1.1	0.6	1.5	-0.2	0.8	0.5	0.5	-0.1
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.3	0.6	1.4	0.1	1.6	2.1	0.7	1.7	-0.7	0.6	-1.1	-1.2	1.0
Ever used hormone-replacement therapy (HRT)	1.5	1.9	4.9	0.6	0.5	-1.3	-1.8	1.2	-0.6	0.9	-2.2	-0.1	-2.2	-2.2	0.5
Ever had hysterectomy (womb removed)	0.7	0.7	2.3	0.9	-0.8	-1.1	-0.7	0.8	-0.9	0.6	-0.8	0.9	-0.7	-0.0	1.5
Systolic blood pressure, automated reading	1.6	4.5	18.8	-0.4	-1.7	-1.0	-2.9	-0.1	-0.1	0.7	-2.3	1.9	-4.3	-3.5	0.9
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	4.9	-0.5	-1.7	-0.5	-2.2	1.0	-2.1	1.7	-1.8	0.7	-1.7	-1.6	0.3
Angina	1.3	1.7	8.5	-1.4	-1.6	-0.9	-1.7	-0.9	-2.9	-1.2	0.1	0.7	0.5	0.7	-0.2
Medication for hormone replacement therapy	1.5	1.7	5.4	1.2	0.6	0.2	-1.9	1.9	-1.0	1.4	-1.5	-0.3	-0.4	0.0	2.3
Vitamin and mineral supplements	1.6	2.2	7.7	-0.1	2.8	0.5	0.3	2.7	0.4	1.8	-1.0	0.2	0.3	0.2	2.6
Supplements: Zinc	1.7	1.9	8.2	-1.5	-1.0	-0.9	0.6	-2.3	-1.6	-2.9	-0.1	-0.6	0.6	1.0	-0.1
Medication: Co-codamol	0.9	1.0	3.4	-0.6	0.9	0.5	-1.3	1.8	0.0	0.9	-1.7	-1.0	-0.4	-0.9	0.1
Medication: Metformin	1.2	1.7	4.3	1.7	1.1	1.0	0.9	1.3	1.0	1.1	1.4	-0.0	2.1	2.0	0.3
Diabetes (father)	1.5	1.9	6.8	0.3	-1.8	-1.8	-1.2	-0.3	-2.6	-0.1	-2.3	-0.2	-1.3	-1.0	0.5
Diabetes (mother)	2.1	2.6	5.3	1.4	1.4	0.4	0.0	2.0	1.9	2.3	-0.1	2.1	1.6	1.9	2.0
Severe depression (siblings)	2.4	2.6	4.8	-1.7	-2.1	-0.3	-1.5	-1.8	-1.0	-2.2	-0.5	1.3	1.6	1.9	-2.1
Pack years adult smoking proportion	1.6	2.4	6.1	0.4	0.7	2.1	-1.2	1.5	0.8	1.4	-1.7	2.4	-1.4	-0.5	2.5
Impedance of leg (right)	1.3	6.2	13.7	3.4	2.3	3.2	2.5	2.6	3.3	1.8	3.7	1.4	0.5	-0.7	-2.0
Leg fat-free mass (left)	0.6	3.0	8.6	-2.5	-0.5	-2.4	-0.4	-1.5	-2.9	-2.3	-0.8	-2.3	0.7	0.7	0.9
Trunk fat percentage	0.3	1.2	7.3	-2.7	1.0	-0.8	-1.0	0.3	-0.2	-0.7	-0.5	-0.4	-1.2	-1.3	0.3
Hand grip strength (right)	0.2	0.5	2.0	1.4	1.2	-0.8	0.9	0.3	-0.5	0.3	0.0	0.1	0.2	-0.0	-0.8
Townsend deprivation index at recruitment	1.3	1.8	6.3	-2.0	-0.4	-0.1	1.3	-1.7	-0.9	-2.5	1.4	0.0	0.4	0.3	-2.1
Current tobacco smoking	0.3	0.5	1.7	-0.3	-1.3	0.7	-0.6	-1.1	0.3	-1.0	0.3	0.7	-0.4	-0.0	-0.5
Average weekly fortified wine intake	2.2	2.6	7.0	1.3	1.8	2.3	0.8	1.6	2.6	1.8	1.4	2.4	-0.2	-0.1	-0.0
Maternal smoking around birth	1.5	2.2	10.0	-2.4	-2.2	0.1	-3.2	-1.1	-0.1	-0.7	-0.5	0.2	-0.8	-1.0	-1.6
Fed-up feelings	0.2	0.4	1.6	-0.6	-0.9	0.6	-0.7	-0.4	-0.6	-0.2	0.0	-1.3	0.3	0.0	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.7	-0.7	0.2	-0.2	0.8	-0.4	-1.3	-0.7	0.0	-1.1	-0.0	-0.1	-0.3
Relative age voice broke	0.6	0.9	2.0	0.5	-0.5	0.9	-1.1	0.7	0.0	1.0	-0.7	1.3	1.0	1.4	1.1
Taking other prescription medications	0.7	1.1	4.4	-0.9	-0.1	-0.6	-0.7	0.7	-1.3	0.5	-2.1	1.0	-0.8	-0.3	1.7
Age when periods started (menarche)	0.3	0.8	2.8	0.6	0.3	0.8	0.3	1.0	-0.5	0.8	-0.6	-0.8	0.9	1.1	1.7
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.8	1.3	1.2	-0.7	0.1	1.7	0.8	1.4	-0.9	-0.6	-1.1	-1.0	1.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	5.8	0.8	2.4	0.3	1.9	1.3	0.0	1.0	0.0	-0.1	1.1	0.8	0.9
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.7	-1.0	0.8	-0.0	0.9	0.2	-0.2	-0.1	0.4	-0.8	1.6	1.1	0.7
Qualifications: CSEs or equivalent	0.3	0.4	1.9	0.1	-0.0	-0.1	-1.0	0.4	-0.1	0.7	1.4	-0.1	0.7	0.6	0.2
Serious illness, injury or assault to yourself	0.4	0.4	1.9	-0.8	0.1	-0.3	0.7	-0.2	0.0	-0.4	0.0	0.6	1.3	1.4	-0.2
High blood pressure	0.7	2.0	10.5	-3.2	-0.7	-0.6	-1.8	-0.9	-0.6	-1.0	-0.7	1.2	-2.0	-1.1	0.5
Hayfever, allergic rhinitis or eczema	0.5	1.2	3.1	1.2	0.2	-1.4	-0.4	1.8	-1.6	1.2	-1.2	0.2	-0.5	-1.1	-0.2
Multivitamins +/- minerals	1.4	1.8	6.8	-0.6	-2.0	-0.0	-0.1	-2.2	0.3	-1.7	1.7	-0.4	0.2	-0.1	-2.6
Stomach or abdominal pain in last month	0.4	0.5	3.7	0.1	-0.3	-0.9	0.5	-0.9	-1.9	-0.4	-0.2	0.7	-0.3	0.2	0.0
Supplements: Glucosamine	0.8	1.1	2.7	-0.4	-0.7	-1.6	-0.9	-1.0	-0.7	-0.8	-0.5	0.3	-1.7	-1.5	-1.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.7	0.8	-0.2	-0.1	-0.2	0.3	-0.4	0.7	-0.3	0.7	-0.3	-0.5	0.4
Medication: Atenolol	0.2	0.3	1.1	-1.0	0.2	-0.2	0.0	-0.7	-0.0	-0.7	0.5	-0.2	-0.5	-0.2	0.6
Medication: Levothyroxine sodium	0.9	1.6	9.1	-0.5	-3.0	-1.7	-1.4	-1.2	-1.8	-0.3	-0.6	-0.1	0.2	0.2	-0.0
Sitting height	0.5	3.7	15.7	2.0	1.8	0.5	2.5	0.8	0.9	-0.8	4.0	-1.2	2.8	1.5	-1.1
Chronic bronchitis/emphysema (father)	1.1	1.2	4.6	-0.2	0.9	0.0	-0.4	1.5	0.5	1.4	-1.6	0.4	0.9	1.2	2.1
High blood pressure (mother)	0.6	0.9	3.3	-0.2	0.7	0.1	0.4	0.3	1.1	-0.1	1.8	0.6	1.6	1.5	0.5
Body mass index (BMI)	1.0	4.3	13.0	-3.6	-0.9	-2.6	-2.0	-1.0	-2.1	-1.1	-3.1	-0.8	-2.0	-1.2	2.2
Impedance of leg (left)	1.4	6.6	16.5	3.0	2.5	3.4	2.1	2.3	3.7	1.4	4.1	2.1	1.0	0.1	-2.2
Leg predicted mass (left)	0.6	3.0	8.4	-2.5	-0.5	-2.4	-0.5	-1.6	-2.9	-2.3	-0.9	-2.1	0.7	0.7	0.9
Trunk fat mass	0.3	1.1	6.1	-2.5	0.8	-1.2	-0.8	0.2	-0.7	-0.9	-0.6	-1.0	-0.7	-1.0	0.6
Waist circumference	0.9	3.3	7.5	-2.7	-0.1	-2.4	-1.2	-0.5	-2.5	-0.7	-2.7	-1.1	-1.8	-1.4	2.2
Number of incorrect matches in round	1.0	1.6	4.3	0.0	-2.1	-1.8	-1.6	-0.6	-1.6	0.4	-1.9	0.4	-1.5	-1.0	0.3
Past tobacco smoking	1.9	3.6	13.4	0.8	0.7	-1.6	-0.3	2.1	0.0	2.6	-3.1	-1.2	-1.4	-1.2	3.7
Alcohol usually taken with meals	0.9	1.5	7.8	0.7	1.9	0.5	2.8	1.2	1.4	0.2	0.2	-1.1	0.3	-0.4	-0.5
Nervous feelings	0.3	0.6	2.8	1.1	0.0	-0.7	-0.8	1.2	0.0	1.7	-0.2	0.4	-0.1	-0.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.4	-0.4	-0.1	-0.3	0.5	-0.2	-0.8	-0.2	-1.6	-0.2	-0.3	0.1	1.5
Hearing difficulty/problems with background noise	2.4	3.9	12.1	-3.5	-2.6	0.7	-3.4	-1.9	0.2	-1.9	-0.5	2.2	0.7	1.9	-0.0
Hair/balding pattern: Pattern 2	1.0	1.3	5.5	0.4	-0.2	-1.3	0.8	-0.7	-0.6	-0.7	0.4	-2.4	-1.4	-1.7	-1.0
Had menopause	2.1	2.6	7.6	0.7	-0.6	0.4	-2.8	1.6	1.6	2.1	-1.6	2.3	-1.6	-1.0	1.2
Had other major operations	1.5	1.8	5.2	0.5	1.7	1.3	1.1	1.1	2.3	0.6	1.1	1.6	1.9	1.1	-0.6
Forced vital capacity (FVC)	0.2	0.8	3.6	0.4	0.0	-0.2	1.3	-0.9	0.2	-0.8	1.9	-0.0	0.8	0.3	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	7.3	0.5	2.7	-0.3	1.8	1.9	-0.2	1.2	-1.2	0.2	0.2	0.4	2.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.2	-0.3	-0.0	0.5	1.0	0.3	0.4	-0.2	-0.3	-0.9	0.2	-0.4	-1.1
Qualifications: None of the above	0.5	1.0	3.2	-1.8	0.5	0.3	-1.5	-0.0	0.0	0.1	-1.0	0.9	-1.2	-0.2	1.8
Financial difficulties in last 2 years	2.0	2.7	7.9	-2.1	-1.1	1.7	1.6	-2.2	-1.2	-2.8	1.2	-1.4	1.0	0.9	-1.1
Mouth/teeth dental problems	0.7	1.1	4.9	1.1	-1.0	-0.6	-1.3	-0.0	0.5	0.6	-1.5	0.2	-0.4	-1.0	-2.2
Heart attack	1.0	1.3	5.6	-0.9	-0.6	-0.8	-0.0	-0.4	-2.1	0.3	-0.5	1.4	-0.1	0.9	2.4
Allergy	0.5	1.1	4.5	-0.8	-0.6	1.5	0.5	-2.1	1.2	-1.3	1.1	-0.5	0.1	0.4	0.3
Pain all over the body in last month	0.3	0.3	1.2	-1.1	-0.0	-0.4	0.1	0.9	0.4	0.0	-0.4	0.6	-0.4	-0.4	0.2
Diabetes (self-reported)	0.8	1.3	3.3	1.1	-0.3	0.7	-0.5	1.5	0.8	1.8	1.0	1.5	1.2	1.4	-0.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.0	-0.5	0.5	-0.8	-0.1	1.0	-0.2	0.2	-0.7	-0.9	0.2	-0.1	0.5
Medication: Ramipril	0.7	0.9	4.2	-0.4	0.9	-0.6	-0.4	0.7	-1.1	0.2	-2.0	0.8	-0.5	0.1	1.4
Medication: Simvastatin	1.8	2.6	10.6	-0.4	3.3	1.3	2.6	2.5	0.6	1.3	-0.5	0.2	-0.1	-0.1	1.8
Fluid intelligence score	0.3	0.7	2.1	1.3	-0.6	0.6	1.4	0.1	1.1	0.2	0.3	-1.4	0.5	-0.0	-0.8
Illnesses of siblings	0.4	0.5	1.5	-0.2	1.2	-0.5	1.1	0.7	0.7	0.7	-0.6	-0.3	-0.7	-0.8	-0.1
Neuroticism score	0.3	0.6	1.7	-0.4	-1.3	0.2	-1.0	-0.6	-1.3	-0.3	0.4	0.3	0.7	1.0	-0.6
Weight	0.3	1.6	5.2	-2.3	0.5	-2.0	-0.3	-0.1	-1.6	-1.1	-1.0	-1.5	-0.1	-0.1	1.6
Impedance of arm (right)	0.9	4.0	16.6	1.8	1.1	2.3	1.8	0.6	2.1	-0.5	4.1	0.4	1.1	-0.2	-3.4
Arm fat percentage (right)	0.6	2.3	11.7	-3.4	-0.3	-1.6	-1.5	-0.7	-1.0	-1.5	-1.5	-0.5	-1.6	-1.4	0.5
Trunk fat-free mass	0.3	1.6	4.9	-1.0	-0.2	-2.2	0.2	-0.9	-1.9	-1.3	-0.5	-1.2	1.2	1.3	1.3
Hip circumference	0.4	1.8	7.6	-2.8	0.7	-2.0	-0.9	-0.4	-0.8	-1.2	-1.8	-0.9	-0.4	-0.1	1.6
Time employed in main current job	0.5	0.6	2.1	-0.5	1.5	1.2	1.0	0.9	1.1	0.1	-0.1	0.1	-0.1	-0.3	0.3
Alcohol intake versus 10 years previously	0.8	1.2	4.3	-0.2	0.3	-2.1	0.2	0.9	-0.5	0.9	-1.2	-0.8	-1.4	-1.2	1.5
Father’s age at death	1.3	1.8	4.7	1.9	1.3	-1.4	1.6	1.7	2.2	1.4	-0.1	1.1	0.6	0.7	0.5
Worrier / anxious feelings	0.2	0.3	1.8	0.7	-0.7	-0.3	0.7	-0.2	-1.3	0.4	-0.2	0.3	0.2	0.3	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	4.5	-0.6	0.2	-1.2	1.0	0.3	-2.1	-0.4	-1.5	0.4	-2.1	-1.8	0.8
Falls in the last year	0.6	0.8	3.7	0.1	0.2	0.9	0.7	0.6	-0.2	0.4	1.1	-0.8	1.9	1.4	0.3
Hair/balding pattern: Pattern 3	0.4	0.6	2.2	-1.1	0.1	-0.1	-0.3	-0.7	-1.0	-0.0	-0.9	1.3	-0.4	0.3	1.5
Number of live births	2.7	3.8	11.8	-2.6	-2.3	1.3	-1.1	-3.4	1.0	-2.8	1.5	1.2	0.7	1.1	-2.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	7.9	1.0	0.5	-0.2	2.3	-0.3	0.4	-0.5	2.8	0.1	0.8	-0.1	-2.5
Pulse rate	0.8	1.3	4.7	1.6	1.4	-1.0	1.0	1.6	-0.3	1.2	-0.7	0.0	-0.5	-0.3	2.2
Happiness	0.2	0.2	0.9	0.6	0.3	-1.0	0.6	0.1	-0.3	-0.6	-0.0	0.3	-0.4	-0.2	0.2
Noisy workplace	0.7	0.8	2.1	-1.4	0.7	1.4	-0.3	0.6	0.1	0.6	-0.0	0.8	0.9	1.2	1.2
Qualifications: A levels/AS levels or equivalent	0.8	1.8	10.6	1.1	1.9	-0.5	3.2	0.7	-0.6	-0.3	1.1	-1.0	1.4	-0.0	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.2	-0.8	0.6	0.4	0.2	0.2	0.9	0.6	-0.1	-0.1	1.5	1.3	1.3
Mouth/teeth dental problems: Dentures	0.2	0.4	1.7	-0.7	-0.4	0.5	-0.3	-0.2	1.1	-0.1	0.2	0.7	-0.3	0.7	1.3
Asthma	0.4	0.8	2.5	-1.6	-1.0	-0.5	-0.5	-0.1	-1.2	-0.8	-0.6	1.5	0.3	0.6	-0.4
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	5.2	-0.0	-1.4	0.6	0.3	-2.3	-1.3	-2.2	0.4	-1.2	0.3	0.3	-2.2
Medication: Cholesterol lowering	1.5	2.4	8.5	1.2	2.9	0.6	1.2	2.4	0.2	2.2	-0.9	0.5	0.5	0.6	2.1
Depression (self-reported)	1.0	1.2	2.8	0.4	0.7	-1.2	1.6	-0.1	-1.2	-0.5	-0.2	-1.2	-1.4	-1.7	-1.4
Medication: Lansoprazole	1.7	1.9	7.0	0.3	1.8	-0.3	0.7	2.6	0.0	2.2	-0.7	-0.4	-0.0	-0.3	2.6
Prospective memory result	0.4	0.5	3.1	-0.8	-0.5	-0.3	-1.8	-0.4	0.4	-0.2	0.2	-0.1	0.7	0.7	0.3
Lung cancer (father)	1.6	1.9	8.0	-0.9	-2.5	0.3	-2.8	-1.5	1.1	-0.5	-0.5	-0.5	-1.3	-1.0	-0.9
Illnesses of mother	0.9	1.1	5.0	-0.2	0.3	0.1	1.0	-0.1	-0.8	-0.1	-0.6	-1.4	-1.5	-2.2	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	8.1	1.6	0.9	0.4	2.9	0.6	1.0	0.5	2.5	-0.1	1.0	-0.2	-2.5
Pulse wave Arterial Stiffness index	0.3	0.4	1.6	-1.3	-0.0	0.3	-0.8	-0.3	-0.5	-0.2	-0.8	0.1	-0.4	0.2	0.9
Impedance of arm (left)	0.9	4.1	16.2	1.9	2.1	2.2	2.1	1.3	2.0	0.0	4.0	0.1	1.3	-0.0	-2.9
Arm fat mass (right)	0.7	2.7	11.6	-3.4	-0.4	-2.3	-1.4	-0.9	-1.6	-1.6	-1.7	-1.2	-1.1	-0.9	1.2
Trunk predicted mass	0.2	1.4	4.1	-1.0	-0.2	-2.0	0.3	-0.8	-1.7	-1.3	-0.3	-1.1	1.4	1.4	1.3
Standing height	0.5	5.4	19.0	1.9	2.3	0.5	3.1	1.2	0.4	-0.8	4.4	-1.4	3.9	2.3	-1.4
Length of working week for main job	0.7	0.8	3.7	-1.4	-0.1	-0.8	0.3	-0.8	-0.3	-1.4	0.1	-1.9	0.1	0.0	-0.3
Exposure to tobacco smoke at home	1.2	1.3	5.8	0.3	0.8	2.4	1.2	0.3	1.1	-0.3	1.5	-0.2	1.2	0.3	-1.6
Breastfed as a baby	0.7	0.8	2.9	-0.4	0.4	1.7	0.1	1.4	-0.8	0.8	-1.6	0.1	0.9	0.3	0.2
Tense / ‘highly strung’	0.3	0.5	2.4	-0.4	-0.7	-1.6	-0.5	-0.2	-1.0	0.3	-0.5	-1.0	-0.3	-0.4	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	5.7	1.5	1.8	1.1	2.4	1.0	1.4	0.1	0.8	-0.3	0.0	-0.7	-1.0
Hair/balding pattern: Pattern 4	0.3	0.8	2.1	0.8	1.0	-0.9	1.1	0.7	-0.3	1.5	-1.2	-0.3	-0.4	-0.3	1.1
Birth weight of first child	0.3	0.5	1.7	0.9	-0.3	1.1	0.2	0.3	1.3	0.2	1.0	0.3	0.8	0.6	-0.6
Peak expiratory flow (PEF)	0.9	2.2	11.0	0.6	0.9	0.1	2.5	-0.0	0.5	-0.3	3.3	0.3	0.3	-0.6	-2.6
Pulse wave reflection index	2.0	2.4	6.7	-1.8	-2.6	-0.6	-2.4	-1.8	-2.2	-1.3	-1.0	0.0	0.4	1.2	0.6
Ever highly irritable/argumentative for 2 days	0.8	0.9	3.2	1.2	-0.5	0.2	-0.8	1.6	0.1	1.8	-0.9	0.6	-0.1	-0.0	1.3
Loud music exposure frequency	0.6	0.7	1.7	-0.4	-1.3	-1.2	-0.6	-1.2	-0.6	-0.8	-0.4	-1.1	-0.6	-0.5	-0.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	5.9	1.3	0.5	1.1	1.4	0.4	0.6	-0.0	1.7	-0.7	-0.0	-1.3	-2.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	6.2	-0.2	1.8	0.3	1.4	0.0	-0.5	-0.7	2.5	-0.6	0.5	-0.1	0.2
Blood clot in the leg (DVT)	1.2	1.6	5.5	1.3	2.3	-0.2	1.0	2.3	0.1	2.1	-0.1	0.4	0.6	0.4	0.7
Medication: Paracetamol	1.0	1.7	5.2	-0.7	-1.7	-0.8	-2.2	-1.3	-1.1	-0.7	-2.3	-0.9	0.0	0.6	1.3
Headache pain in last month	0.4	0.7	2.5	-0.6	-0.6	-0.4	0.5	-1.6	-0.4	-1.6	-0.3	-0.3	-0.4	0.6	0.9
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	5.3	-0.8	-1.6	-0.6	0.2	-1.6	-0.1	-1.9	1.2	-0.7	-1.0	-1.5	-2.3
Glaucoma (self-reported)	1.7	2.0	6.9	-1.2	-1.8	-2.6	-2.1	-0.8	-1.3	-0.1	-2.1	0.7	-0.5	0.1	1.1
Gout (self-reported)	0.6	0.8	3.9	-0.3	-1.4	-0.6	-2.0	-0.5	-0.1	0.7	-1.5	-0.5	-0.7	-0.5	-0.0
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	8.5	-1.3	-2.9	-2.4	-1.9	-1.2	-1.6	-0.5	-1.1	0.5	-0.9	-0.4	0.3
Medication: Amlodipine	0.6	0.8	2.4	-0.9	-0.5	0.7	0.1	0.5	-1.5	0.8	-1.6	-1.1	-0.0	-0.2	1.1
Medication: Ventolin 100micrograms inhaler	1.8	2.3	7.6	-2.8	-1.0	-1.3	-2.2	-1.4	-2.1	-1.2	-1.6	0.7	-0.6	0.6	0.9
Birth weight	0.9	2.0	7.2	0.3	0.2	-1.2	2.0	-0.9	0.2	-0.5	1.7	-2.5	0.7	-0.5	-2.7
Chronic bronchitis/emphysema (mother)	1.2	1.3	5.6	-0.6	-0.0	-0.2	-1.3	0.7	-0.1	0.7	-2.4	1.4	-1.4	-0.8	1.7
High blood pressure (siblings)	0.2	0.3	1.1	0.4	-0.5	0.1	-0.6	0.1	0.1	0.1	0.5	0.9	-0.4	0.3	1.1
Forced vital capacity (FVC), Best measure	0.3	0.9	3.8	1.1	0.4	0.1	1.9	0.1	0.6	0.4	1.6	0.2	0.7	-0.1	-1.6
Body fat percentage	0.3	1.2	6.4	-2.5	0.7	-0.7	-1.0	0.4	-0.2	-0.5	-1.0	-0.2	-1.5	-1.4	0.8
Leg fat percentage (right)	0.5	1.7	4.7	-1.8	0.3	-0.3	-1.0	0.9	-0.3	0.5	-1.8	0.1	-2.2	-1.8	1.8
Arm fat-free mass (right)	0.2	1.1	2.9	-1.1	0.1	-1.7	-0.3	-0.3	-1.6	-0.7	-0.8	-1.0	0.8	0.8	1.6
Exposure to tobacco smoke outside home	1.0	1.3	2.9	-1.7	1.7	1.4	1.1	1.1	1.2	-0.0	0.5	-1.1	1.4	-0.0	-1.0
Comparative body size at age 10	0.5	1.3	4.6	-1.1	-0.5	0.7	-0.5	-0.9	-0.1	-1.6	1.1	1.6	0.8	0.5	-2.1
Number of full brothers	0.6	0.8	2.3	-1.1	-1.0	0.2	-0.6	-0.8	-0.4	-1.2	0.5	0.2	1.4	1.5	0.5
Worry too long after embarrassment	0.8	1.3	3.8	-0.2	-1.6	0.2	-1.9	-0.8	-0.4	-0.3	0.6	0.5	1.5	1.5	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.5	4.8	0.5	2.1	1.7	2.2	1.5	2.0	0.3	1.9	-0.3	2.1	0.9	-1.7
Wheeze or whistling in the chest in last year	1.8	3.1	7.3	-2.3	-2.6	-0.6	-2.7	-2.7	-1.6	-1.8	-1.3	0.9	0.1	1.5	0.6
Number of children fathered	0.7	0.8	2.6	-0.7	-0.9	0.7	-1.6	-0.5	0.3	-0.1	-0.6	0.4	1.2	1.4	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.8	-1.0	-1.4	-0.8	-1.7	-1.1	-1.2	-0.5	-1.1	1.2	0.5	1.2	0.1
Age at first live birth	1.7	2.9	8.2	2.9	1.8	1.5	2.7	1.6	0.8	1.3	0.9	-1.1	2.0	1.4	1.4
Pulse wave peak to peak time	0.4	0.4	2.2	1.5	0.1	-0.3	0.8	0.5	0.5	0.2	0.9	-0.3	0.5	-0.1	-0.8
Health satisfaction	0.8	1.0	4.9	0.9	0.8	2.2	0.9	0.7	0.0	-0.0	0.5	1.8	-0.6	-0.5	-0.3
Shortness of breath walking on level ground	1.5	1.8	5.7	0.6	0.5	0.6	-1.3	2.3	0.1	2.2	-1.4	0.8	0.1	0.3	2.4
Qualifications: College or University degree	1.1	3.5	23.6	1.8	1.8	-0.6	4.9	-0.8	-0.3	-1.1	1.9	-1.2	0.3	-0.7	-1.9
Eye problems/disorders: None of the above	0.6	0.7	2.3	0.7	0.6	1.4	1.1	0.1	0.0	-0.1	0.9	-1.5	0.8	0.3	-0.1
Mouth/teeth dental problems: Loose teeth	0.7	0.8	5.2	-0.2	0.9	0.4	0.5	1.4	0.5	0.3	0.4	2.3	-0.6	-0.5	0.3
Emphysema/chronic bronchitis	0.4	0.4	1.3	-0.6	-0.8	-0.5	-0.6	-0.5	-1.1	-0.3	-0.8	-0.1	0.2	1.0	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	2.7	-0.3	1.6	0.2	0.7	1.2	1.5	0.8	0.4	0.1	-0.6	-1.1	0.2
Neck or shoulder pain in last month	0.3	0.4	1.4	-0.8	0.5	0.5	-0.5	0.5	0.0	0.3	-0.2	1.2	-0.2	0.4	1.2
Medication: Blood pressure	0.6	1.0	2.8	-0.9	-0.9	-0.7	-1.6	-0.6	-1.4	0.3	-1.3	-0.1	-0.3	0.5	1.7
Angina (self-reported)	1.0	1.4	7.0	-1.5	-1.3	-0.8	-1.3	-0.8	-2.6	-1.2	0.3	0.7	0.2	0.4	-0.2
Migraine (self-reported)	0.4	0.5	1.5	-0.9	-0.5	0.6	-0.4	-1.2	0.2	-1.2	0.8	0.0	0.4	0.4	-0.5
Medication: Ibuprofen	0.9	1.1	4.7	0.2	-0.9	0.3	0.5	-1.9	-0.5	-1.7	0.4	-0.8	0.2	0.1	-2.2
Medication: Allopurinol	0.7	1.0	3.2	-0.8	-1.8	-0.9	-1.7	-0.9	-0.7	0.0	-1.2	-1.0	-0.0	-0.1	-0.6
Medication: Omeprazole	0.4	0.5	1.3	0.8	0.1	-0.0	-0.5	1.0	-0.1	1.0	0.3	1.2	-0.8	-0.7	0.3
Medication: Seretide 50 evohaler	4.5	5.2	12.8	-3.2	-2.8	-1.3	-2.0	-3.6	-3.1	-3.2	-1.5	1.2	-0.3	1.5	-0.2
Mean time to correctly identify matches	1.2	2.2	8.1	0.4	0.3	0.7	-1.4	2.1	0.4	1.7	-2.8	1.4	-1.8	-1.1	1.4
Heart disease (mother)	0.7	0.8	4.2	-0.5	0.0	0.0	-1.0	0.4	-0.2	0.8	-1.0	1.3	-0.7	0.1	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	4.0	-2.0	-1.5	-0.4	-1.5	-1.4	-0.0	-1.8	1.2	1.1	-0.4	-0.3	-1.7
Whole body fat mass	0.4	1.6	7.9	-2.8	0.3	-1.5	-1.0	-0.3	-1.2	-1.2	-1.1	-1.0	-1.0	-0.9	1.0
Leg fat mass (right)	0.4	1.5	5.5	-2.4	0.1	-1.2	-0.9	-0.0	-1.0	-0.6	-1.7	-1.0	-1.2	-1.1	1.5
Arm predicted mass (right)	0.2	1.1	3.0	-1.3	0.1	-1.7	-0.2	-0.4	-1.7	-0.9	-0.9	-1.0	0.7	0.8	1.5
Pulse rate, automated reading	1.9	6.0	17.2	3.8	4.2	-0.2	3.6	3.0	1.5	2.5	0.0	1.1	-0.6	-0.4	2.8
Alcohol intake frequency.	1.1	2.5	7.0	0.1	2.6	-1.7	1.1	2.2	1.5	1.7	-0.4	0.8	-1.8	-1.5	1.7
Comparative height size at age 10	0.5	2.5	8.4	0.6	2.2	0.2	1.5	0.8	0.3	-0.8	2.8	0.0	2.9	2.3	-0.1
Number of full sisters	0.7	0.8	2.9	0.2	-1.7	0.1	-1.3	-0.7	-1.2	-0.6	-0.2	-1.2	-0.7	-0.5	-0.8
Suffer from ‘nerves’	0.5	0.8	2.5	0.1	-1.1	-1.4	0.3	0.5	-1.1	0.7	-1.4	-0.4	0.2	0.3	1.6
Overall health rating	1.2	2.6	11.0	-1.7	0.4	0.0	0.2	0.4	-1.9	0.2	-1.7	1.3	-3.3	-2.6	1.2
Chest pain or discomfort	1.3	1.8	7.6	-1.5	-0.5	-0.9	-1.1	-0.7	-1.1	-0.3	-1.1	2.8	-1.2	0.0	2.4
Had major operations	0.3	0.3	2.0	-0.0	0.8	-0.5	1.0	-0.0	-1.4	-0.3	-0.2	0.1	0.1	0.1	0.0
Age at last live birth	1.0	1.5	3.8	0.8	0.1	1.7	1.5	-0.8	0.8	-1.0	1.7	-0.2	1.9	1.8	-0.1
Family relationship satisfaction	1.0	1.2	3.3	-0.7	-1.8	-0.0	-0.7	-1.8	-1.1	-1.6	-0.8	0.5	-0.2	0.4	-1.5
Leg pain on walking	1.5	1.9	4.3	-0.7	1.6	0.9	-0.7	1.9	-0.1	1.4	-1.1	1.6	-2.1	-2.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	5.1	-0.7	-1.7	-0.1	-1.3	-1.3	-0.5	-0.4	0.3	-2.3	0.8	0.6	-0.2
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.5	-0.4	-1.1	0.8	-1.1	-1.1	0.4	0.3	1.4	-1.6	-0.2	-0.8	-1.1
Illness, injury, bereavement, stress in last 2 years	1.9	2.4	6.5	1.7	1.0	0.3	-0.7	2.2	0.7	1.9	-1.1	0.4	-2.5	-2.5	1.0
Medication: Aspirin	0.6	0.8	3.5	0.0	-0.9	-0.8	0.5	-0.6	-1.9	-0.2	-0.1	-0.2	1.1	1.4	1.0
Supplements: Vitamin C	0.3	0.4	2.8	0.5	0.0	-1.7	0.4	-0.3	-0.3	-0.5	-0.0	0.4	0.5	0.7	-0.4
Knee pain experienced in last month	0.2	0.3	1.3	-1.1	0.0	-0.6	-0.4	-0.1	-0.7	0.3	0.2	-0.5	-0.2	-0.3	0.7
Hypertension (Self-reported)	0.7	1.9	8.9	-3.0	-1.1	-0.6	-2.1	-1.2	-0.8	-1.1	-0.8	0.9	-1.7	-0.8	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.0	0.6	0.0	-1.4	-0.6	0.9	-1.2	0.6	-0.8	0.3	-1.3	-1.0	0.4
Illnesses of father: Heart disease	0.4	0.6	2.2	0.1	0.7	0.8	0.3	0.8	0.4	0.8	0.9	0.5	1.5	0.9	-0.5
Illnesses of siblings: Diabetes	1.2	1.5	7.5	0.5	-2.1	0.4	-2.7	-0.1	-0.3	0.5	-0.5	1.4	1.2	1.1	-0.6
Smoking status: Previous	1.2	1.8	9.4	0.1	0.0	0.7	0.6	-1.1	-0.4	-1.6	2.4	0.8	0.9	0.6	-3.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.5	-0.3	0.6	-0.4	0.7	-0.7	-1.2	-1.6	1.1	-1.9	1.5	0.7	-1.5
Whole body fat-free mass	0.4	2.1	6.1	-1.7	-0.3	-2.5	-0.1	-1.1	-2.4	-1.7	-0.7	-1.6	1.0	1.1	1.2
Leg fat-free mass (right)	0.5	2.9	7.4	-2.4	-0.6	-2.5	-0.6	-1.7	-2.7	-2.4	-0.7	-1.8	1.0	1.1	0.8
Arm fat percentage (left)	0.5	2.0	10.1	-3.2	0.2	-1.6	-1.3	-0.3	-1.0	-1.1	-1.5	-0.7	-1.4	-1.2	0.9
Average weekly red wine intake	0.8	1.1	7.2	0.7	1.0	1.4	2.7	0.7	0.4	0.1	0.2	-0.7	0.6	-0.3	-0.9
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.3	-1.0	-0.4	0.2	-0.3	-0.8	0.6	-0.4	-0.3	1.2	-0.6	-0.1	-0.1
Mood swings	0.1	0.2	0.7	0.3	-0.6	0.8	-0.2	-0.0	-0.9	0.1	0.6	0.2	0.2	0.7	0.3
Loneliness, isolation	0.4	0.6	1.7	-0.5	1.3	1.1	0.4	1.0	0.2	0.7	-0.4	0.9	0.2	0.5	1.1
Long-standing illness, disability or infirmity	1.2	1.8	7.2	-0.2	2.7	0.0	1.4	2.2	-0.5	1.1	-0.8	1.4	-0.2	-0.0	1.8
Ever had bowel cancer screening	1.1	1.3	5.1	1.7	0.9	1.1	2.3	0.5	0.9	0.8	1.2	-1.1	0.9	0.1	-0.4
Diabetes diagnosed by doctor	0.9	1.5	5.3	1.6	-0.0	0.9	-0.4	2.1	1.2	2.3	0.8	1.0	1.0	0.8	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	3.0	-0.1	0.8	0.1	0.8	-0.6	0.6	-1.0	0.2	-0.0	-0.7	-0.8	-1.7
Friendships satisfaction	0.7	0.9	3.7	-0.4	0.7	-0.1	1.7	-0.5	-0.5	-1.6	0.7	0.3	-0.0	-0.3	-1.9
Qualifications: nursing, teaching	1.9	3.0	9.5	1.9	2.9	0.2	1.9	3.1	1.6	2.0	0.2	1.5	0.9	-0.1	-0.7
Commuting to job workplace: Walk	2.1	2.2	5.3	0.4	2.0	0.8	2.0	1.2	1.5	0.0	1.5	2.3	1.5	1.9	0.7
Eye problems/disorders: Cataract	1.1	1.3	5.0	0.1	-0.6	-0.6	-1.0	-0.7	1.2	-0.9	1.5	1.5	1.0	0.8	-2.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	4.1	-2.0	1.2	1.2	-0.1	0.6	0.4	-0.1	0.2	-0.0	0.6	0.7	0.7
Medication for cholesterol	0.6	1.0	2.4	-0.0	-1.3	-0.7	-0.1	-1.5	-0.4	-0.3	0.1	1.2	1.4	1.3	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.0	0.6	0.7	0.8	0.3	1.4	0.5	1.2	-1.4	0.7	-1.4	-0.8	1.4
Back pain experienced in last month	0.5	0.8	4.3	-0.6	2.1	0.9	1.2	1.2	0.3	0.8	-0.3	0.2	0.5	0.0	-0.1
Mineral and other dietary supplements	0.8	1.1	3.0	0.6	1.7	1.4	1.1	1.7	0.8	1.0	0.4	-0.2	1.0	0.7	0.6
Breast cancer (self-reported)	0.9	1.1	3.3	0.7	-1.1	0.1	-0.7	-1.1	0.8	-0.6	1.8	-0.4	1.3	0.6	-1.8
Asthma (self-reported)	0.5	1.0	4.0	-2.0	-0.9	-0.8	-0.7	-0.0	-1.3	-0.8	-0.8	1.6	0.1	0.4	-0.3
Osteoporosis (self-reported)	0.4	0.5	1.4	0.3	0.4	0.5	-0.1	1.2	0.5	0.7	-0.3	0.2	-1.2	-1.0	0.7
Osteoarthritis (self-reported)	1.0	1.4	6.1	-1.0	-0.7	-2.5	0.1	-0.7	-1.3	-0.4	-0.6	-1.7	-1.4	-1.2	0.2
Medication: Aspirin	0.6	0.8	2.3	0.2	-0.4	-0.5	0.8	-0.0	-1.5	0.4	0.1	-0.3	1.4	1.5	1.4
Medication: Gliclazide	0.4	0.4	1.5	-0.4	0.3	0.3	-0.4	-0.9	-0.8	-0.9	0.4	-0.3	0.8	1.2	0.2
Illnesses of father: None of the above (group 1)	0.9	1.1	2.7	-0.8	-1.1	0.4	-0.8	-1.7	0.1	-1.5	0.3	-0.9	-1.3	-1.4	-1.0
Smoking status: Current	0.6	0.9	3.2	-0.7	-1.8	0.7	-1.0	-1.7	0.3	-1.3	0.4	0.6	-0.1	0.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.5	0.3	-0.3	-0.4	1.2	0.3	0.2	0.6	-0.3	0.4	-0.5	-0.7	-0.4
Whole body water mass	0.4	2.1	5.8	-1.7	-0.3	-2.4	-0.1	-1.0	-2.3	-1.6	-0.8	-1.6	1.0	1.1	1.3
Leg predicted mass (right)	0.5	2.8	6.7	-2.4	-0.5	-2.4	-0.6	-1.6	-2.6	-2.3	-0.7	-1.9	1.1	1.1	0.7
Arm fat mass (left)	0.7	2.7	11.8	-3.4	0.1	-2.4	-1.2	-0.7	-1.7	-1.5	-1.7	-1.1	-1.3	-1.0	1.3
Number of self-reported non-cancer illnesses	0.8	1.4	3.4	-0.3	0.6	0.1	-0.8	1.8	0.4	1.5	-1.0	1.8	-1.8	-1.4	0.1
Average weekly champagne plus white wine intake	0.3	0.5	1.3	0.1	-0.4	0.7	-0.4	-0.6	0.2	-1.1	0.0	1.1	0.7	1.1	-0.2
Miserableness	0.6	1.0	3.5	-0.8	-0.6	0.4	0.5	-1.0	-1.9	-1.5	1.6	0.4	-0.1	0.2	-0.7
Guilty feelings	0.7	1.1	2.6	-0.0	-0.7	-0.1	0.5	-1.4	-0.6	-1.2	1.1	-0.7	1.6	1.3	-1.5
Wears glasses or contact lenses	2.7	3.1	10.5	0.4	2.5	1.6	0.7	2.0	2.9	1.5	-1.1	3.2	-0.8	0.0	0.7
Ever taken oral contraceptive pill	0.7	0.8	2.7	-0.9	1.4	0.5	1.4	0.1	0.2	-0.5	-1.6	-1.0	0.2	0.4	0.8
Hearing aid user	0.5	0.6	4.1	-0.4	-0.5	0.7	-0.2	-0.7	-0.1	-0.5	0.4	0.8	-0.4	-0.1	-2.0
Mother’s age at death	0.2	0.3	1.9	0.7	-0.2	0.2	0.2	-0.5	0.4	0.0	0.4	-1.4	0.4	0.2	-0.5
Financial situation satisfaction	0.4	0.5	2.2	-1.1	-0.2	0.5	0.3	-0.6	-1.0	-1.5	-0.8	0.1	-0.6	-0.1	0.4
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.0	-2.0	-1.0	0.8	-0.5	-1.9	1.4	-2.0	1.8	1.2	1.1	1.6	-1.5
Commuting to job workplace: Public transport	1.1	1.3	2.5	0.8	1.6	-1.0	1.6	1.3	0.0	0.6	-0.5	-0.6	-1.4	-1.4	1.3
Eye problems/disorders: Glaucoma	1.1	1.3	3.0	-0.9	-1.6	-1.7	-1.6	-0.5	-0.8	0.1	-1.6	1.2	-0.4	0.4	1.1
Medication: Blood pressure	0.6	1.1	4.8	-2.2	0.5	-0.2	-0.1	-0.1	0.3	-0.8	-0.4	0.3	-2.0	-1.5	0.5
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.5	1.2	1.2	0.2	1.2	1.2	0.1	1.0	1.9	0.6	1.1	0.9	-0.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.2	-0.4	-1.8	-0.5	-1.2	-1.7	-0.6	-0.8	0.2	0.7	-0.2	0.1	-0.6
High cholesterol (Self-reported)	0.6	1.0	5.8	0.1	2.4	0.1	1.6	1.7	0.2	0.4	0.5	0.8	-0.0	0.0	0.2
Medication: Bendroflumethiazide	1.2	1.8	7.5	-2.7	-0.6	-1.1	-0.2	-1.3	-1.4	-1.7	-1.5	-1.0	-1.2	-0.6	1.0
Medication: Paracetamol	1.1	1.7	4.4	-1.1	-1.6	-1.5	-1.5	-1.9	-1.1	-1.2	-2.1	-0.5	-0.4	0.5	1.3
Medication: Lisinopril	0.3	0.4	1.6	0.1	0.1	-0.1	0.1	0.2	0.2	0.9	0.2	-0.4	-1.1	-1.3	-0.6
Medication: Atorvastatin	0.8	0.9	2.3	1.3	-0.9	-1.2	-0.7	0.5	-1.5	0.4	-0.4	1.3	-1.1	-0.5	0.9
Illnesses of father: High blood pressure	0.5	0.7	2.0	-1.4	0.4	-0.6	0.7	-0.6	-0.1	-0.9	1.0	0.3	0.9	1.4	0.2
Alcohol drinker status: Never	1.5	1.8	8.5	-2.2	1.1	-2.9	0.2	-0.3	0.6	-0.1	-0.8	1.1	-1.8	-0.8	1.1
Ever smoked	1.8	3.2	8.0	-1.0	-0.4	1.5	0.7	-2.1	-0.1	-2.7	2.5	1.2	1.7	1.7	-2.8
Basal metabolic rate	0.4	2.3	6.4	-2.1	-0.1	-2.5	-0.1	-1.1	-2.4	-1.8	-0.8	-1.7	0.7	0.8	1.3
Leg fat percentage (left)	0.4	1.5	4.2	-2.0	0.5	-0.3	-1.3	0.7	-0.2	0.3	-1.7	0.6	-1.7	-1.2	1.8
Arm fat-free mass (left)	0.3	1.7	5.2	-1.6	-0.3	-2.3	-0.5	-0.6	-2.0	-1.0	-1.4	-1.0	0.3	0.5	1.8
Number of operations (self-reported)	0.2	0.2	0.8	-0.8	0.7	-0.2	0.3	0.1	-0.4	-0.2	0.1	0.9	0.6	0.5	-0.1
Average weekly beer plus cider intake	1.4	2.1	6.0	-1.5	-1.8	-1.0	-2.4	-2.2	-1.9	-1.6	-0.6	-0.3	-1.1	-0.2	-0.0
Irritability	0.4	0.6	1.8	0.8	-1.2	0.9	-0.0	0.2	-1.3	0.8	-0.2	-0.2	1.0	0.9	0.5
Risk taking	0.4	0.6	2.1	0.9	0.9	1.5	1.1	0.4	0.5	-0.2	0.7	0.3	0.4	0.6	0.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.1	1.4	0.5	-0.5	0.8	0.5	0.4	0.5	-0.6	1.5	0.1	-0.0	-1.4
Fractured/broken bones in last 5 years	1.4	1.8	5.1	2.0	0.1	-0.4	0.4	1.8	-1.0	2.2	-0.2	-1.2	-0.9	-0.8	2.2
Age started oral contraceptive pill	1.4	1.7	7.8	-0.3	0.4	-0.3	1.2	0.5	0.2	1.0	-1.4	-0.3	-2.6	-2.8	1.0
Diastolic blood pressure, automated reading	1.0	3.0	14.6	-0.1	-2.2	-1.8	-3.8	-1.4	-0.2	-0.4	-1.1	1.5	-1.0	0.5	2.4
Ever depressed for a whole week	0.8	1.0	3.2	-1.7	0.6	1.5	1.4	-0.7	0.1	-1.8	-0.4	0.0	0.5	0.7	-0.6
Unable to work because of sickness or disability	1.4	1.9	5.3	0.1	2.3	1.5	2.1	2.0	0.7	1.0	-0.8	-0.1	1.1	0.8	1.5
Commuting to job workplace: Cycle	3.2	3.9	10.3	-1.7	-3.2	-3.0	-0.8	-3.0	-2.4	-2.5	-1.1	-0.9	-0.1	0.8	-0.1
Myopia	0.2	0.3	0.9	0.9	-0.9	0.5	-0.1	0.4	-1.0	0.3	-0.5	-0.1	0.6	0.4	-0.0
Vascular/heart problems diagnosed by doctor	0.8	2.1	11.8	3.4	0.4	0.1	1.8	0.8	1.0	1.1	0.5	-1.8	1.4	0.3	-1.0
Cholesterol lowering medication	0.5	0.8	2.3	-0.4	1.1	1.1	0.9	1.5	1.1	0.1	0.2	0.7	-1.1	-0.8	0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	4.1	0.1	0.5	-0.1	-0.6	0.6	0.2	0.2	0.0	2.0	-0.6	-0.2	0.5
Pain experienced in last month	0.4	0.7	2.8	1.7	0.1	-0.2	-0.3	0.7	0.5	1.3	-0.2	-1.2	-0.4	-0.8	-0.1
Supplements: Calcium	0.8	0.9	2.0	0.5	0.8	0.6	1.1	0.2	1.4	-0.0	1.2	-0.8	1.4	0.5	-1.3
Basal cell carcinoma (self-reported)	1.6	1.9	9.2	0.0	-0.7	-1.0	1.5	-0.8	0.4	-1.0	1.8	-3.0	0.3	-1.0	-1.8
Heart attack/myocardial infarction (self-reported)	0.9	1.1	5.7	-0.7	-0.4	-0.5	0.1	-0.1	-2.0	0.4	-0.4	1.4	-0.1	0.8	2.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	5.9	1.1	2.3	-0.3	0.7	2.4	0.0	2.1	-0.2	0.7	0.5	0.3	0.6
Heart disease (siblings)	0.9	1.1	3.5	-0.4	-1.0	0.7	-0.4	-1.2	0.0	-1.1	0.8	-1.8	1.2	0.4	-1.9
Alcohol drinker status: Previous	1.4	1.6	4.3	0.9	2.1	1.5	1.7	1.3	1.9	0.8	0.4	-0.1	-0.4	-1.0	-1.1
Pack years of smoking	2.2	3.3	8.5	0.7	0.7	2.2	-1.5	2.0	1.2	2.1	-2.0	2.7	-1.3	-0.4	2.9
Impedance of whole body	1.1	5.4	18.2	2.6	2.3	2.7	2.0	1.9	2.9	0.7	4.3	1.1	1.1	-0.1	-2.9
Leg fat mass (left)	0.4	1.5	6.2	-2.5	0.2	-1.2	-1.1	-0.1	-1.0	-0.7	-1.6	-0.7	-1.0	-0.7	1.6
Arm predicted mass (left)	0.3	1.6	5.2	-1.8	-0.2	-2.3	-0.3	-0.6	-1.9	-1.2	-1.1	-0.9	0.2	0.4	1.6