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chr9:108,998-1,162,143

Best TWAS P=1.1e-37 · Best GWAS P=7.01e-39 conditioned to 0.00315

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CBWD1	0.39	0.39	bslmm	450	0.40	1.3e-52	-11.3	-10.9	1.3e-27	0.82	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FOXD4	0.13	0.04	lasso	6	0.05	9.9e-07	-3.9	-7.3	2.5e-13	0.55	0.78	0.22	FALSE
3	GTEx	Adipose Subcutaneous	CBWD1	0.37	0.22	enet	17	0.23	5.2e-19	-7.5	-10.8	4.6e-27	0.87	0.01	0.99	FALSE
4	GTEx	Adipose Visceral Omentum	CBWD1	0.26	0.06	enet	30	0.14	1.7e-07	-11.1	-9.3	1.9e-20	0.80	0.08	0.92	FALSE
5	GTEx	Adrenal Gland	CBWD1	0.45	0.10	enet	28	0.11	9.5e-05	-13.0	-10.7	1.4e-26	0.81	0.00	0.99	FALSE
6	GTEx	Artery Aorta	CBWD1	0.26	0.09	enet	20	0.16	3.1e-09	-11.1	-9.2	3.1e-20	0.76	0.16	0.84	FALSE
7	GTEx	Artery Coronary	CBWD1	0.35	0.12	enet	12	0.17	2.7e-06	3.9	-10.2	1.4e-24	0.76	0.02	0.96	FALSE
8	GTEx	Artery Tibial	CBWD1	0.33	0.21	enet	10	0.22	3.0e-17	-13.0	-12.0	4.3e-33	0.92	0.00	1.00	FALSE
9	GTEx	Brain Caudate basal ganglia	CBWD1	0.23	0.11	lasso	3	0.02	7.5e-02	-10.9	-10.7	1.6e-26	0.83	0.05	0.82	FALSE
10	GTEx	Brain Cortex	DOCK8	0.22	0.05	lasso	5	0.04	3.2e-02	-8.5	-8.1	5.5e-16	0.68	0.07	0.61	FALSE
11	GTEx	Brain Cortex	CBWD1	0.37	0.20	lasso	3	0.25	1.4e-07	-7.5	-8.6	1.2e-17	0.73	0.29	0.62	FALSE
12	GTEx	Brain Frontal Cortex BA9	CBWD1	0.24	0.17	enet	16	0.17	3.0e-05	-7.5	-7.9	3.8e-15	0.65	0.03	0.87	FALSE
13	GTEx	Brain Hippocampus	CBWD1	0.23	0.04	enet	21	0.01	1.5e-01	-13.0	-8.9	7.6e-19	0.72	0.02	0.89	FALSE
14	GTEx	Brain Nucleus accumbens basal ganglia	CBWD1	0.34	0.18	lasso	4	0.19	7.5e-06	-7.5	-8.2	2.4e-16	0.70	0.19	0.80	FALSE
15	GTEx	Brain Putamen basal ganglia	CBWD1	0.32	0.06	enet	18	0.13	4.6e-04	-7.5	-9.2	3.1e-20	0.77	0.02	0.90	FALSE
16	GTEx	Breast Mammary Tissue	CBWD1	0.23	0.06	lasso	4	0.09	2.1e-05	-7.7	-10.0	1.2e-23	0.79	0.23	0.73	FALSE
17	GTEx	Cells EBV-transformed lymphocytes	CBWD1	0.29	0.17	lasso	5	0.17	3.5e-06	-7.5	-10.5	8.7e-26	0.84	0.01	0.98	FALSE
18	GTEx	Cells Transformed fibroblasts	CBWD1	0.61	0.29	enet	18	0.45	4.1e-37	-7.5	-11.2	5.6e-29	0.88	0.00	1.00	FALSE
19	GTEx	Colon Sigmoid	CBWD1	0.23	0.06	enet	11	0.09	5.9e-04	-7.7	-9.2	5.8e-20	0.78	0.01	0.98	FALSE
20	GTEx	Colon Transverse	CBWD1	0.44	0.32	enet	22	0.28	1.3e-13	-11.1	-11.1	7.7e-29	0.88	0.06	0.94	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	CBWD1	0.15	0.11	enet	9	0.09	4.4e-04	-11.1	-11.9	1.6e-32	0.88	0.01	0.98	FALSE
22	GTEx	Esophagus Mucosa	DOCK8	0.08	0.04	lasso	6	0.04	1.2e-03	-8.2	-9.1	6.5e-20	0.78	0.15	0.69	FALSE
23	GTEx	Esophagus Mucosa	CBWD1	0.43	0.41	enet	23	0.49	6.4e-37	-11.0	-11.0	5.5e-28	0.87	0.24	0.76	FALSE
24	GTEx	Esophagus Muscularis	CBWD1	0.20	0.08	enet	39	0.08	1.9e-05	-11.1	-6.6	5.3e-11	0.67	0.01	0.99	FALSE
25	GTEx	Heart Atrial Appendage	CBWD1	0.48	0.20	lasso	9	0.26	4.5e-12	-11.0	-11.6	3.7e-31	0.91	0.02	0.98	FALSE
26	GTEx	Heart Left Ventricle	CBWD1	0.33	0.10	enet	44	0.17	1.4e-09	-13.0	-11.9	1.1e-32	0.75	0.00	1.00	FALSE
27	GTEx	Liver	CBWD1	0.30	0.00	lasso	4	0.04	3.4e-02	-11.0	-10.6	2.0e-26	0.84	0.03	0.78	FALSE
28	GTEx	Lung	CBWD1	0.24	0.15	lasso	5	0.18	1.0e-13	-13.0	-12.5	5.2e-36	0.96	0.00	1.00	FALSE
29	GTEx	Muscle Skeletal	CBWD1	0.31	0.17	enet	8	0.23	1.7e-22	-12.2	-12.6	2.0e-36	0.94	0.00	1.00	FALSE
30	GTEx	Nerve Tibial	CBWD1	0.35	0.24	lasso	7	0.23	1.7e-16	-7.5	-10.0	1.1e-23	0.81	0.72	0.28	FALSE
31	GTEx	Pancreas	DOCK8	0.39	0.24	lasso	7	0.26	1.5e-11	11.7	11.8	2.7e-32	-0.66	0.02	0.98	TRUE
32	GTEx	Pancreas	CBWD1	0.20	0.03	enet	20	0.06	2.0e-03	-10.9	-10.7	8.2e-27	0.87	0.01	0.97	FALSE
33	GTEx	Pituitary	CBWD1	0.47	0.16	enet	8	0.18	2.8e-05	-8.3	-8.6	6.6e-18	0.74	0.17	0.79	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	CBWD1	0.49	0.23	enet	16	0.41	6.2e-24	-13.0	-10.5	7.0e-26	0.87	0.00	1.00	FALSE
35	GTEx	Skin Sun Exposed Lower leg	CBWD1	0.43	0.21	enet	21	0.37	1.3e-31	-13.0	-11.1	1.5e-28	0.88	0.00	1.00	FALSE
36	GTEx	Small Intestine Terminal Ileum	CBWD1	0.30	0.19	lasso	2	0.22	1.2e-05	-11.0	-12.4	2.5e-35	0.93	0.01	0.95	FALSE
37	GTEx	Spleen	CBWD1	0.24	-0.01	lasso	6	0.00	3.1e-01	-11.0	-11.2	5.5e-29	0.86	0.02	0.88	FALSE
38	GTEx	Testis	CBWD1	0.46	0.28	enet	23	0.36	1.5e-16	-11.1	-12.3	9.1e-35	0.90	0.03	0.97	FALSE
39	GTEx	Thyroid	CBWD1	0.38	0.24	lasso	4	0.32	1.8e-25	-7.5	-11.5	1.8e-30	0.91	0.00	1.00	FALSE
40	GTEx	Vagina	CBWD1	0.52	0.21	enet	28	0.32	3.6e-08	-13.0	-9.3	1.3e-20	0.80	0.01	0.99	FALSE
41	METSIM	Adipose	CBWD1	0.08	0.07	lasso	3	0.07	2.2e-10	-11.3	-11.3	8.0e-30	0.85	0.19	0.81	FALSE
42	ROSMAP	Brain Pre-frontal Cortex	DOCK8	0.08	0.02	enet	16	0.06	1.2e-07	-11.0	-7.4	1.8e-13	0.62	0.19	0.80	FALSE
43	ROSMAP	Brain Pre-frontal Cortex	FOXD4	0.24	0.05	blup	371	0.13	7.9e-17	-3.9	-7.6	2.2e-14	0.46	0.27	0.73	FALSE
44	ROSMAP	Brain Pre-frontal Cortex	CBWD1	0.31	0.27	lasso	7	0.26	9.2e-34	-11.3	-11.9	1.5e-32	0.90	0.38	0.62	FALSE
45	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CBWD1	0.09	0.09	lasso	3	0.09	1.1e-07	-11.3	-11.5	1.4e-30	0.86	0.02	0.98	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	CBWD1	0.11	0.10	lasso	2	0.10	1.9e-19	-11.3	-11.7	7.1e-32	0.88	0.92	0.08	FALSE
47	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CBWD1	0.25	0.19	enet	7	0.20	3.1e-10	-11.3	-12.2	1.9e-34	0.87	0.02	0.98	FALSE
48	The Cancer Genome Atlas	Colon Adenocarcinoma	CBWD1	0.28	0.19	enet	9	0.27	4.3e-16	-10.9	-10.8	3.1e-27	0.84	0.10	0.90	FALSE
49	The Cancer Genome Atlas	Glioblastoma Multiforme	CBWD1	0.14	0.06	blup	30	0.08	2.4e-03	-10.9	-12.6	3.3e-36	0.92	0.01	0.73	FALSE
50	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CBWD1	0.11	0.11	lasso	3	0.13	2.1e-14	-11.3	-12.5	1.0e-35	0.91	0.02	0.98	FALSE
51	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C9orf66	0.05	0.04	lasso	4	0.04	1.0e-05	-12.0	9.8	8.8e-23	-0.83	0.06	0.92	FALSE
52	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CBWD1	0.06	0.02	enet	17	0.05	2.2e-06	-13.0	-7.8	7.4e-15	0.72	0.00	1.00	FALSE
53	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CBWD1	0.26	0.04	blup	30	0.09	1.2e-05	-6.7	-6.4	1.2e-10	0.50	0.07	0.10	FALSE
54	The Cancer Genome Atlas	Brain Lower Grade Glioma	CBWD1	0.15	0.11	lasso	3	0.11	1.4e-12	-11.3	-11.7	1.0e-31	0.90	0.32	0.68	FALSE
55	The Cancer Genome Atlas	Brain Lower Grade Glioma	DOCK8	0.12	0.10	enet	13	0.12	3.9e-13	-12.0	-9.0	3.1e-19	0.78	0.58	0.42	FALSE
56	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CBWD1	0.50	0.20	lasso	2	0.18	6.6e-09	-11.3	-11.6	2.9e-31	0.88	0.21	0.79	FALSE
57	The Cancer Genome Atlas	Lung Adenocarcinoma	CBWD1	0.16	0.19	lasso	3	0.19	7.2e-22	-11.3	-11.9	2.0e-32	0.89	0.07	0.93	FALSE
58	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CBWD1	0.07	0.08	enet	4	0.09	1.8e-10	-11.3	-11.8	2.4e-32	0.91	0.01	0.99	FALSE
59	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C9orf66	0.09	0.02	enet	7	0.02	1.3e-02	-8.3	-5.5	5.1e-08	0.50	0.06	0.15	FALSE
60	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CBWD1	0.11	0.09	enet	5	0.10	5.6e-07	-10.9	-12.3	1.4e-34	0.93	0.00	1.00	FALSE
61	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CBWD1	0.10	0.10	blup	30	0.11	1.9e-05	-11.0	-12.6	2.6e-36	0.92	0.01	0.97	FALSE
62	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CBWD1	0.08	0.07	enet	8	0.06	2.4e-03	-11.1	-11.7	1.5e-31	0.85	0.02	0.75	FALSE
63	The Cancer Genome Atlas	Prostate Adenocarcinoma	CBWD1	0.10	0.08	enet	7	0.11	2.2e-11	-11.3	-12.5	6.5e-36	0.90	0.00	1.00	FALSE
64	The Cancer Genome Atlas	Rectum Adenocarcinoma	CBWD1	0.40	0.14	blup	30	0.26	9.9e-07	-11.3	-12.3	1.5e-34	0.88	0.01	0.94	FALSE
65	The Cancer Genome Atlas	Soft Tissue Sarcoma	CBWD1	0.06	0.02	blup	30	0.03	8.8e-03	-11.1	-10.4	2.3e-25	0.83	0.01	0.81	FALSE
66	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CBWD1	0.18	0.05	enet	3	0.03	6.1e-02	-11.3	-12.0	2.8e-33	0.91	0.00	0.62	FALSE
67	The Cancer Genome Atlas	Stomach Adenocarcinoma	CBWD1	0.26	0.17	blup	30	0.22	1.5e-15	-10.9	-9.5	2.4e-21	0.80	0.52	0.48	FALSE
68	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CBWD1	0.12	0.03	blup	30	0.06	3.4e-03	-11.1	-12.8	1.1e-37	0.89	0.01	0.87	TRUE
69	The Cancer Genome Atlas	Thyroid Carcinoma	CBWD1	0.20	0.16	blup	30	0.21	4.1e-20	-13.0	-12.1	1.0e-33	0.92	0.00	1.00	FALSE
70	The Cancer Genome Atlas	Thyroid Carcinoma	DOCK8	0.10	0.05	lasso	3	0.05	2.6e-05	-10.9	-9.2	3.9e-20	0.75	0.17	0.76	FALSE
71	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CBWD1	0.15	0.13	lasso	2	0.10	8.8e-04	-7.0	-7.0	2.7e-12	0.57	0.03	0.12	FALSE