TWAS hub - PARP10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.0740	0.0360	9.4e-03	0.028	NA	0.000	NA	0.013	1.3e-02	NA	3.4e-01	NA	6.7e-02
2	GTEx	Artery Tibial	0.0792	0.0321	6.6e-04	0.011	NA	0.017	NA	0.017	4.0e-02	NA	1.6e-02	NA	1.6e-02
3	GTEx	Colon Transverse	0.0990	0.0360	4.9e-04	0.036	NA	0.049	NA	0.059	8.1e-03	NA	2.3e-03	NA	9.0e-04
4	GTEx	Esophagus Mucosa	0.0760	0.0330	2.2e-03	0.027	NA	0.040	NA	0.029	6.1e-03	NA	1.0e-03	NA	5.0e-03
5	GTEx	Nerve Tibial	0.0821	0.0318	2.4e-04	0.056	NA	0.065	NA	0.052	8.5e-05	NA	2.2e-05	NA	1.4e-04
6	GTEx	Ovary	0.2190	0.0890	9.4e-03	0.046	NA	0.042	NA	0.075	2.8e-02	NA	3.5e-02	NA	6.8e-03
7	GTEx	Skin Sun Exposed Lower leg	0.0580	0.0240	1.0e-03	0.043	NA	0.029	NA	0.044	1.8e-04	NA	1.8e-03	NA	1.4e-04
8	GTEx	Thyroid	0.0790	0.0300	2.0e-04	0.091	NA	0.086	NA	0.085	1.9e-07	NA	4.0e-07	NA	4.4e-07
9	METSIM	Adipose	0.0798	0.0218	4.8e-14	0.133	0.105	0.117	0.119	0.128	2.4e-19	1.9e-15	4.3e-17	2.7e-17	1.4e-18
10	ROSMAP	Brain Pre-frontal Cortex	0.1032	0.0355	1.4e-06	0.081	0.048	0.074	0.069	0.077	1.4e-10	8.0e-07	8.5e-10	3.0e-09	3.7e-10
11	YFS	Blood	0.1068	0.0327	1.1e-16	0.072	0.065	0.074	0.079	0.074	1.9e-22	2.0e-20	3.8e-23	1.1e-24	5.3e-23

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Blood Platelet Count	34.2	396.9	470.9	-20.0	-20.1	-19.8	-17.7	-20.9	-20.4	-21.7	-19.5	-19.9	-20.8	-18.0
LDL Cholesterol	23.0	36.3	44.6	-6.6	-5.1	-6.0	-4.3	-6.4	-6.7	-6.3	-6.3	-6.4	-6.1	-5.7
Medication: Cholesterol lowering	13.2	20.5	25.2	-4.8	-3.9	-4.4	-2.9	-4.3	-5.0	-4.9	-5.0	-5.0	-4.7	-4.4
Comparative height size at age 10	13.0	71.3	91.6	8.8	6.0	8.6	7.6	9.6	7.7	9.0	8.9	8.8	8.3	9.2
Standing height	12.9	127.9	162.6	11.7	9.9	11.8	10.6	12.8	10.8	11.8	11.5	11.6	11.0	10.7
Average weekly fortified wine intake	11.5	13.5	15.9	3.7	3.6	3.8	4.0	3.8	3.9	4.0	3.5	3.5	3.5	3.0
Height	11.3	216.9	285.6	15.1	12.4	15.5	14.3	16.9	15.3	15.4	14.6	14.6	14.4	13.0
Sitting height	10.5	74.5	102.0	8.7	6.9	9.2	9.4	10.1	8.0	8.8	8.3	8.2	8.2	8.8
Schizophrenia vs Biploar Disorder	9.8	12.9	17.5	3.9	0.0	3.8	2.7	3.8	4.2	3.8	4.1	4.2	3.2	3.7
Medication: Atorvastatin	9.7	11.9	15.4	-3.5	-1.9	-3.4	-2.8	-3.9	-3.4	-3.7	-3.7	-3.9	-3.4	-3.9
Medication: Simvastatin	9.6	14.0	18.8	-4.3	-2.7	-3.8	-2.5	-3.8	-4.1	-4.0	-4.2	-4.1	-3.5	-3.7
High cholesterol (Self-reported)	9.2	16.3	21.6	-4.2	-2.1	-3.9	-3.1	-4.4	-4.5	-4.3	-4.3	-4.3	-4.1	-4.6
Arm fat-free mass (right)	8.2	42.1	54.1	6.2	5.1	6.7	7.3	7.4	7.2	7.0	6.0	6.1	6.0	5.9
Arm predicted mass (right)	8.0	40.7	54.5	5.9	5.0	6.6	7.4	7.3	7.3	6.9	5.7	5.9	5.9	5.6
Trunk fat-free mass	7.8	44.8	57.0	6.4	5.7	7.0	7.5	7.5	7.2	7.1	6.3	6.4	6.1	6.1
Trunk predicted mass	7.5	42.9	54.7	6.3	5.5	6.8	7.4	7.4	7.0	7.0	6.2	6.3	5.9	6.0
Forced expiratory volume in 1-second (FEV1), predicted	7.5	15.6	21.8	4.3	2.8	3.9	2.8	4.6	3.1	4.3	4.2	4.2	3.9	4.7
Average weekly red wine intake	7.3	10.8	16.3	3.2	3.2	3.4	4.0	3.7	3.3	3.4	3.1	3.1	3.0	2.6
Arm fat-free mass (left)	7.1	36.1	49.2	5.7	4.6	6.2	6.7	7.0	6.6	6.4	5.6	5.7	5.4	5.7
Arm predicted mass (left)	6.7	34.2	46.4	5.6	4.5	6.0	6.5	6.8	6.6	6.3	5.5	5.6	5.2	5.4
Whole body fat-free mass	6.0	34.2	46.0	5.5	4.5	6.1	6.8	6.8	6.3	6.2	5.5	5.6	5.2	5.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.7	6.8	9.2	-2.8	-1.0	-2.7	-2.8	-2.7	-3.0	-2.8	-2.7	-2.7	-2.3	-2.6
Whole body water mass	5.7	32.8	44.2	5.4	4.4	6.0	6.6	6.7	6.2	6.1	5.3	5.5	5.1	5.4
Cholesterol lowering medication	5.3	7.8	10.6	-2.9	-1.6	-2.8	-2.4	-3.2	-3.0	-2.8	-3.0	-3.0	-3.0	-2.7
Breastfed as a baby	5.0	6.2	10.6	-3.1	-1.3	-2.4	-0.9	-2.8	-1.9	-2.7	-3.3	-3.2	-2.2	-2.4
Supplements: Vitamin C	5.0	5.9	10.4	2.4	2.0	2.5	2.7	2.6	1.9	2.4	2.4	2.4	3.2	2.0
Basal metabolic rate	4.8	26.8	38.7	4.8	3.8	5.4	6.0	6.2	5.7	5.5	4.8	4.8	4.5	4.9
Hair/balding pattern: Pattern 2	4.7	6.0	8.4	2.7	1.6	2.3	1.9	2.6	2.5	2.7	2.8	2.9	2.7	2.0
Medication: Ventolin 100micrograms inhaler	4.6	5.9	11.4	2.6	1.4	2.9	3.4	2.4	1.7	2.7	2.5	2.5	2.1	1.8
Tinnitus: Yes, but not now, but have in the past	4.2	4.5	8.3	2.1	1.4	2.2	2.9	2.2	2.4	2.4	2.0	2.0	2.2	1.1
Maternal smoking around birth	3.8	5.5	9.4	2.6	2.3	2.5	1.4	2.4	3.1	2.4	2.3	2.3	2.8	1.0
Falls in the last year	3.8	5.2	9.9	-2.7	-0.9	-2.5	-2.1	-2.2	-1.5	-2.3	-2.4	-2.2	-2.3	-3.2
Mother’s age at death	3.8	4.8	7.0	2.1	2.0	2.6	2.6	2.6	2.7	2.0	1.9	1.9	1.9	1.4
Forced vital capacity (FVC), Best measure	3.7	13.7	18.5	3.8	2.7	3.7	4.1	3.5	4.3	3.7	3.8	3.8	3.9	3.0
Bipolar Disorder (2018)	3.6	5.7	8.9	-2.6	-2.0	-2.7	-1.9	-2.5	-2.9	-2.1	-2.5	-2.3	-1.5	-3.0
Waist Hip Ratio (WHR)	3.6	16.1	23.8	3.4	4.9	4.2	2.8	4.7	3.8	4.3	3.9	4.2	4.2	3.1
Stomach or abdominal pain in last month	3.6	4.4	6.8	2.1	2.2	1.9	1.4	1.8	2.2	2.6	2.0	2.1	2.6	2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	3.6	5.4	8.0	-2.4	-1.0	-2.5	-2.4	-2.4	-2.8	-2.4	-2.2	-2.1	-2.2	-2.7
Bipolar Disorder or Schizophrenia	3.4	8.3	13.9	-2.9	-2.0	-3.2	-3.1	-3.2	-3.7	-2.6	-2.7	-2.6	-2.3	-2.9
Age when periods started (menarche)	3.4	8.1	12.2	3.2	2.6	3.5	2.5	2.8	2.5	2.7	2.8	2.6	3.2	2.6
Blood Red Count	3.3	32.2	37.9	5.3	5.9	5.8	6.2	5.9	6.1	5.8	5.3	5.4	6.0	4.5
Commuting to job workplace: Car/motor vehicle	3.3	3.7	7.7	-2.3	-1.4	-1.7	-1.1	-1.7	-1.8	-2.2	-2.1	-2.1	-2.8	-1.4
Illness, injury, bereavement, stress in last 2 years	3.3	4.1	7.8	1.9	1.1	1.8	2.8	2.1	1.7	2.1	1.7	1.6	2.6	2.3
Medication for cholesterol	3.1	4.7	7.5	2.5	1.3	2.2	1.4	2.5	2.7	2.1	2.2	2.1	2.3	2.0
Ever taken oral contraceptive pill	3.0	3.3	5.8	1.5	0.6	2.0	2.4	2.3	1.8	1.7	1.5	1.6	1.7	2.2
Forced vital capacity (FVC)	2.9	11.3	16.0	3.4	2.6	3.2	3.5	3.3	4.0	3.5	3.4	3.4	3.8	2.5
Long-standing illness, disability or infirmity	2.9	4.4	6.3	-2.1	-1.4	-1.9	-2.5	-1.8	-2.1	-2.3	-2.3	-2.2	-1.6	-2.3
Friendships satisfaction	2.8	3.5	5.2	2.2	0.9	1.8	1.1	1.7	1.4	2.1	2.3	2.3	2.1	2.2
Ever depressed for a whole week	2.8	3.4	5.0	-2.1	-1.6	-1.6	-0.7	-1.8	-2.2	-1.9	-2.0	-2.0	-1.9	-2.0
Chronotype (morning person)	2.7	6.3	10.1	-2.3	-1.3	-2.4	-2.2	-3.0	-2.4	-2.8	-2.4	-2.6	-2.6	-3.2
Ever had hysterectomy (womb removed)	2.7	3.0	4.9	1.8	2.2	1.7	1.3	1.6	1.5	1.8	1.9	2.0	1.9	0.9
Leg predicted mass (left)	2.7	14.2	22.7	3.4	2.3	4.0	4.7	4.8	4.1	3.9	3.4	3.5	3.0	3.7
Mouth/teeth dental problems	2.7	4.1	5.8	2.2	0.5	2.3	2.4	2.3	1.4	2.4	2.3	2.4	1.7	1.5
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	6.9	-1.4	-0.6	-1.9	-2.6	-1.9	-1.8	-2.2	-1.6	-1.8	-2.4	-1.5
Leg fat-free mass (right)	2.7	14.7	23.0	3.5	2.2	4.1	4.8	4.7	4.1	4.0	3.5	3.6	3.1	3.7
Leg fat-free mass (left)	2.6	13.7	22.1	3.3	2.2	3.9	4.6	4.7	4.0	3.9	3.4	3.5	3.0	3.7
Qualifications: College or University degree	2.6	8.3	12.0	3.2	2.9	3.1	2.9	2.8	2.0	2.8	3.0	3.0	3.5	2.3
Leg predicted mass (right)	2.6	14.1	22.7	3.4	2.2	4.1	4.8	4.6	4.0	3.9	3.4	3.5	3.1	3.6
Relative age voice broke	2.5	3.8	6.8	2.2	1.7	2.0	1.0	2.0	2.5	1.9	2.0	1.9	2.6	0.7
Serious illness, injury or assault to yourself	2.4	3.0	4.1	-1.8	-1.7	-1.5	-1.5	-1.8	-1.3	-1.8	-1.7	-1.8	-2.0	-2.0
Weight	2.4	11.9	22.4	2.9	1.9	3.5	4.2	4.7	4.1	3.6	2.9	3.0	2.6	3.4
Relative age of first facial hair	2.3	4.7	10.1	2.1	2.7	2.1	1.4	2.0	3.2	2.4	1.9	1.9	2.5	-0.1
High blood pressure (mother)	2.3	3.2	7.1	-1.6	-2.5	-1.5	-1.2	-1.9	-1.8	-1.8	-1.6	-1.5	-2.7	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	5.2	1.6	1.0	2.1	2.3	1.9	1.4	1.8	1.4	1.4	1.6	1.2
Pulse wave peak to peak time	2.3	2.7	4.3	2.0	2.0	1.6	0.7	1.1	1.0	1.7	2.1	2.1	1.7	1.6
Leg pain on walking	2.3	2.9	4.2	-1.7	-1.3	-1.6	-1.4	-2.0	-1.6	-1.7	-1.8	-1.8	-1.5	-2.0
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	4.5	1.7	1.0	1.6	1.1	1.7	2.1	1.9	1.9	1.9	1.7	1.3
Severe depression (siblings)	2.1	2.4	5.7	-1.6	-0.6	-2.0	-2.4	-1.6	-1.6	-1.5	-1.3	-1.2	-1.5	-1.0
Depression (self-reported)	2.1	2.5	5.9	-1.5	-1.3	-1.4	-2.4	-1.6	-1.5	-1.7	-1.4	-1.4	-1.0	-1.7
Alcohol intake frequency.	2.1	4.8	7.2	-2.2	-0.6	-2.2	-2.2	-2.7	-2.2	-2.3	-2.3	-2.3	-2.2	-2.4
Guilty feelings	2.1	3.1	3.6	1.7	1.8	1.8	1.8	1.7	1.9	1.8	1.7	1.7	1.6	1.8
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	3.4	-1.5	-1.1	-1.7	-0.8	-1.8	-1.6	-1.5	-1.6	-1.6	-1.5	-1.2
Vitamin and mineral supplements	2.0	2.7	4.3	-1.7	-2.1	-1.5	-1.2	-1.7	-0.9	-1.9	-1.6	-1.7	-1.9	-1.3
Medication: Co-codamol	2.0	2.3	3.3	-1.7	-1.1	-1.5	-1.7	-1.3	-0.7	-1.6	-1.7	-1.7	-1.8	-1.4
Noisy workplace	2.0	2.4	4.1	-1.5	-1.3	-1.7	-2.0	-1.7	-1.6	-1.5	-1.3	-1.4	-1.8	-1.1
Chest pain or discomfort	2.0	2.8	4.2	2.0	1.6	2.1	1.0	1.7	1.1	1.7	2.1	1.9	1.2	1.8
Ever had prostate specific antigen (PSA) test	2.0	2.4	6.4	-1.8	-1.2	-1.4	-0.2	-1.1	-2.5	-1.5	-1.8	-1.8	-1.5	-0.8
Diabetes (self-reported)	1.9	3.0	6.3	1.1	2.5	1.4	1.2	2.2	1.7	1.6	0.7	0.9	2.3	2.2
Birth weight of first child	1.9	3.5	7.4	1.7	2.1	2.0	2.7	2.1	1.3	1.5	1.8	1.7	1.6	1.4
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	3.1	-1.5	-1.5	-1.6	-1.7	-1.6	-1.2	-1.4	-1.5	-1.5	-1.7	-1.2
Tanning	1.8	22.4	35.8	4.7	3.2	4.6	6.0	4.7	5.0	4.9	4.5	4.5	5.1	4.6
Arm fat percentage (right)	1.8	7.2	11.9	-3.2	-3.2	-2.7	-2.0	-1.2	-1.9	-2.9	-3.0	-3.0	-3.5	-1.7
Pulse rate	1.8	3.1	5.8	-2.2	-1.8	-1.2	-0.5	-1.0	-1.5	-1.8	-2.4	-2.4	-1.9	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	7.3	-1.0	-0.2	-1.7	-2.7	-1.7	-1.9	-1.5	-0.9	-1.0	-1.6	-1.2
Arm fat percentage (left)	1.8	7.2	12.4	-3.2	-3.2	-2.7	-2.0	-1.3	-1.9	-2.9	-3.0	-3.0	-3.5	-1.7
Hand grip strength (left)	1.7	4.4	8.3	2.2	1.3	2.4	2.9	2.4	2.0	1.9	2.0	1.8	2.0	1.8
Multivitamins +/- minerals	1.7	2.2	3.0	1.4	1.7	1.7	1.6	1.7	0.9	1.5	1.3	1.3	1.6	1.4
Medication for cholesterol, blood pressure or diabetes	1.7	2.8	4.4	1.6	1.2	1.7	0.6	1.7	2.1	1.8	1.8	1.8	1.3	1.9
Asthma (self-reported)	1.7	3.4	12.4	1.6	1.1	2.0	3.5	2.0	1.7	1.9	1.4	1.6	1.2	0.7
Osteoporosis (self-reported)	1.7	2.1	4.1	-1.4	-1.4	-1.6	-2.0	-1.2	-1.5	-1.4	-1.3	-1.3	-1.6	-0.5
Tinnitus: Yes, now most or all of the time	1.7	2.0	5.2	-1.4	-2.2	-1.0	-0.7	-1.0	-1.2	-1.6	-1.3	-1.3	-2.3	-0.4
Medication: Blood pressure	1.7	3.3	6.5	-1.9	-0.2	-2.1	-1.7	-2.2	-2.5	-1.8	-1.6	-1.5	-2.0	-1.5
Diabetes (mother)	1.6	2.0	3.8	1.6	-0.3	1.7	0.6	1.7	1.0	1.4	1.9	1.9	0.8	1.5
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	3.3	-1.5	-0.9	-1.1	-0.9	-1.2	-1.4	-1.7	-1.5	-1.6	-1.8	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.5	-1.0	-1.3	-1.7	-2.1	-1.3	-1.9	-1.3	-0.9	-0.8	-1.1	-1.0
Schizophrenia (2018)	1.5	3.2	6.2	-1.6	-0.8	-1.9	-2.4	-2.0	-2.5	-1.7	-1.4	-1.5	-1.8	-1.3
Number of treatments/medications taken	1.5	2.8	5.8	-1.6	-1.3	-1.7	-0.9	-1.7	-2.4	-1.8	-1.8	-1.8	-1.6	-1.4
Pain all over the body in last month	1.5	1.7	3.3	1.4	0.0	1.3	0.9	1.3	1.7	1.5	1.1	1.1	1.8	1.1
Age at first live birth	1.5	2.7	4.8	-1.7	-0.7	-1.6	-0.4	-1.4	-2.0	-1.9	-1.8	-1.9	-1.3	-2.2
Ever used hormone-replacement therapy (HRT)	1.4	1.8	5.8	-1.6	-2.4	-1.3	0.1	-1.2	-1.1	-0.9	-1.6	-1.5	-1.1	-0.3
Impedance of leg (left)	1.4	6.9	14.1	3.0	3.8	2.5	0.5	2.5	2.4	2.5	2.8	2.8	2.9	2.0
Asthma	1.4	2.8	11.0	1.4	0.8	1.8	3.3	1.9	1.7	1.8	1.2	1.4	1.1	0.6
Medication: Allopurinol	1.4	1.9	3.0	1.1	1.6	1.2	1.3	1.6	1.3	1.5	1.1	1.3	1.1	1.7
Ever had bowel cancer screening	1.4	1.7	2.8	-1.6	-1.3	-1.3	-0.4	-1.0	-1.6	-1.4	-1.7	-1.6	-1.1	-0.6
Number of self-reported non-cancer illnesses	1.4	2.4	3.5	-1.8	-0.1	-1.8	-0.9	-1.6	-1.8	-1.4	-1.6	-1.3	-1.9	-1.9
Illnesses of father: High blood pressure	1.4	1.7	4.0	-1.2	-2.0	-1.2	-1.6	-1.4	-1.6	-1.3	-1.1	-1.0	-0.9	-0.4
Ulcerative Colitis (UC)	1.3	2.5	4.8	-2.1	-0.9	-2.2	-0.9	-1.2	-1.8	-1.2	-2.1	-1.9	-0.9	-1.2
Diabetes (father)	1.3	1.6	4.0	1.0	1.4	1.2	0.6	1.4	1.1	1.3	1.1	1.2	2.0	1.1
Chronic bronchitis/emphysema (father)	1.3	1.5	2.5	-1.3	-0.4	-1.6	-1.2	-1.4	-1.2	-1.1	-1.3	-1.2	-1.2	-1.1
Alcohol intake versus 10 years previously	1.3	2.0	3.3	-1.2	-0.7	-1.6	-1.7	-1.6	-1.8	-1.3	-1.3	-1.3	-1.3	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.0	7.5	2.1	1.2	2.0	2.7	1.4	2.5	1.9	2.1	2.1	2.1	1.4
Shortness of breath walking on level ground	1.3	1.6	3.5	-1.6	0.0	-1.1	-0.6	-1.2	-1.2	-1.2	-1.5	-1.4	-1.1	-1.9
Medication: Omeprazole	1.3	1.5	2.1	-1.4	-1.1	-1.5	-1.3	-1.2	-1.0	-1.1	-1.4	-1.3	-1.4	-0.5
Illnesses of father: None of the above (group 1)	1.3	1.6	2.8	1.7	1.4	1.5	0.8	1.2	1.1	1.2	1.5	1.3	1.1	0.8
Impedance of leg (right)	1.2	5.7	13.2	2.7	3.6	2.1	0.2	2.4	2.1	2.2	2.5	2.4	2.7	1.9
Hand grip strength (right)	1.2	3.3	5.8	2.0	2.4	1.9	1.9	2.0	1.7	1.6	1.8	1.7	1.5	1.2
Hair/balding pattern: Pattern 3	1.2	1.7	4.9	-1.5	-1.0	-0.7	-0.5	-1.0	-1.3	-1.7	-1.5	-1.5	-2.2	-0.7
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.2	1.1	0.9	1.1	0.7	1.8	0.9	1.3	1.2	1.3	1.4	1.1
Worry too long after embarrassment	1.2	2.0	4.3	1.5	1.1	1.3	0.4	1.2	1.4	1.3	1.8	1.9	2.1	0.9
Suffer from ‘nerves’	1.2	1.9	5.3	-1.1	-1.5	-0.8	-1.3	-1.6	-1.2	-1.2	-1.0	-1.1	-1.3	-2.3
Illnesses of father: Heart disease	1.2	1.7	3.0	-1.7	-1.3	-1.7	-1.0	-1.0	-0.9	-1.3	-1.4	-1.2	-1.4	-0.9
Rheumatoid Arthritis	1.1	1.5	2.9	1.2	0.8	1.2	0.7	1.7	1.2	1.0	1.4	1.4	0.6	1.7
Respiratory disease	1.1	2.4	7.2	1.3	0.6	1.7	2.7	1.8	2.0	1.6	1.1	1.2	1.2	0.4
Had menopause	1.1	1.3	3.1	-1.1	-1.8	-1.1	-1.1	-0.8	-1.1	-1.1	-1.0	-1.0	-1.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	4.3	-1.7	-1.6	-1.5	-1.1	-1.9	-1.6	-2.1	-1.4	-1.4	-1.6	-0.9
Ulcerative Colitis	1.0	1.4	3.1	-1.6	-1.2	-1.0	0.3	-0.8	-1.1	-1.0	-1.8	-1.6	-1.1	-0.9
Lung FEV1/FVC ratio	1.0	4.9	7.7	-2.1	-2.6	-2.0	-1.3	-2.8	-2.4	-2.4	-2.0	-2.1	-2.3	-2.3
Number of live births	1.0	1.4	3.3	0.9	1.7	0.5	-0.4	0.8	1.8	1.3	1.1	1.3	1.1	1.1
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	5.2	2.0	1.0	1.8	2.3	1.5	2.2	1.9	1.9	1.9	2.2	1.3
Gout (self-reported)	1.0	1.4	3.8	1.1	1.0	1.0	0.5	1.4	0.8	1.2	1.2	1.2	0.9	1.9
Exposure to tobacco smoke outside home	1.0	1.3	3.7	0.9	0.0	1.3	1.9	0.9	1.6	1.2	0.9	0.9	0.9	0.8
Medication: Seretide 50 evohaler	1.0	1.2	2.4	-0.8	-1.5	-0.7	-0.8	-1.1	-1.6	-1.3	-0.8	-0.9	-1.4	-0.7
Mean time to correctly identify matches	1.0	1.9	3.5	-1.3	-1.3	-1.9	-1.8	-1.5	-1.3	-1.2	-1.1	-1.1	-1.6	-0.7
Crohns Disease (2012)	0.9	1.4	4.1	1.1	1.2	1.2	0.0	2.0	0.6	0.8	1.4	1.4	0.6	1.4
Trunk fat mass	0.9	3.7	12.2	1.3	0.5	1.8	2.1	3.5	2.5	1.7	1.4	1.4	0.9	2.3
Nervous feelings	0.9	1.7	5.4	-1.0	0.5	-0.9	-2.3	-1.1	-1.7	-1.3	-0.8	-0.8	-1.0	-1.8
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.4	-0.9	-1.2	-1.1	-1.4	-1.5	-1.2	-1.2	-0.8	-0.8	-1.3	-1.3
Qualifications: None of the above	0.9	2.0	5.1	-1.4	-1.4	-1.9	-2.3	-1.4	-0.2	-1.1	-1.2	-1.0	-1.8	-0.7
Loud music exposure frequency	0.9	1.0	1.6	0.8	0.3	0.8	1.0	1.1	1.2	1.1	1.1	1.3	1.2	0.7
Medication: Ibuprofen	0.9	1.1	2.7	1.2	-0.2	1.0	0.3	0.9	1.6	1.1	1.2	1.2	1.0	0.8
Commuting to job workplace: Walk	0.9	0.9	3.6	1.0	1.9	0.8	-0.7	0.7	0.1	0.7	1.1	1.1	0.9	0.4
Hearing aid user	0.9	1.0	1.9	-0.9	-0.9	-1.0	-0.7	-1.1	-1.4	-0.7	-1.0	-1.0	-0.9	-1.1
Commuting to job workplace: Public transport	0.9	1.0	1.9	1.3	1.2	0.8	0.2	0.6	1.4	1.1	1.2	1.1	1.3	0.4
Alzheimer’s Disease (including proxy)	0.8	1.2	3.2	-1.3	-1.0	-0.7	0.1	-0.8	-0.2	-1.1	-1.7	-1.8	-0.2	-1.5
Blood White Count	0.8	5.7	9.9	-2.7	-3.1	-2.5	-0.8	-1.7	-2.2	-2.4	-2.8	-2.6	-2.9	-1.1
Hearing difficulty/problems: Yes	0.8	1.2	3.5	0.9	1.9	0.6	0.8	1.0	0.8	1.1	1.0	1.1	1.3	1.0
Taking other prescription medications	0.8	1.2	2.9	-1.3	-1.3	-0.8	-0.4	-0.7	-1.7	-0.9	-1.3	-1.1	-1.0	-1.1
Eye problems/disorders: None of the above	0.8	0.9	1.9	1.2	0.3	0.9	0.8	0.3	0.7	1.1	1.4	1.4	1.0	0.8
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.7	-0.5	0.1	-0.9	-1.1	-0.9	-1.7	-1.2	-0.5	-0.7	-1.5	0.1
Unable to work because of sickness or disability	0.8	1.0	2.7	-0.9	-0.1	-0.9	-1.6	-1.1	-0.2	-1.0	-0.9	-1.0	-1.2	-1.1
Myopia	0.8	1.1	2.2	1.2	0.6	1.3	-0.5	0.9	1.5	1.0	1.1	1.0	1.3	0.8
Reaction Time	0.7	1.4	4.2	-1.0	-1.1	-1.5	-2.1	-1.2	-1.1	-0.9	-0.8	-0.8	-1.3	-0.5
Breast Cancer	0.7	1.6	4.5	0.8	0.5	1.1	2.1	1.9	1.1	1.2	0.9	1.0	1.1	1.5
Fasting Glucose	0.7	0.9	3.2	1.0	1.8	0.7	0.1	0.5	-0.0	1.0	0.8	0.8	1.3	0.9
Primary Biliary Cirrhosis	0.7	1.0	2.2	0.9	0.0	1.2	1.0	1.2	1.5	1.2	0.5	0.5	1.1	0.9
Lung FVC	0.7	3.5	8.4	-1.5	-2.5	-1.9	-1.1	-2.9	-0.2	-1.9	-1.5	-1.5	-1.4	-2.6
Body mass index (BMI)	0.7	3.1	6.1	-2.2	-2.5	-1.7	-0.4	-0.8	-0.5	-1.6	-2.2	-2.1	-2.3	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	9.9	0.7	3.1	0.8	0.8	1.0	1.4	0.7	0.3	0.4	0.9	1.1
Impedance of arm (right)	0.7	3.4	9.9	-1.4	-0.7	-1.8	-3.1	-1.2	-3.0	-2.2	-1.1	-1.2	-1.7	-0.8
Medication: Lansoprazole	0.7	0.8	1.3	-0.9	-0.2	-0.9	-1.0	-1.0	-0.9	-0.9	-1.0	-1.1	-0.8	-0.9
Pulse wave Arterial Stiffness index	0.7	0.8	2.1	-1.1	-1.5	-0.7	0.0	-0.2	-0.2	-0.9	-1.2	-1.2	-1.0	-0.8
Medication: Blood pressure	0.7	1.2	2.8	1.3	0.6	1.1	1.7	0.9	0.5	1.1	1.0	1.0	1.4	0.7
Pulse rate, automated reading	0.7	2.4	4.4	1.2	0.7	1.7	2.0	2.0	1.6	1.5	0.9	0.7	2.1	1.7
Overall health rating	0.7	1.6	6.0	-1.3	-0.2	-1.2	-2.5	-1.2	-1.0	-1.1	-1.2	-1.1	-1.1	-1.0
Diabetes diagnosed by doctor	0.7	1.2	4.7	0.4	2.2	0.6	0.7	1.2	0.9	1.0	-0.0	0.2	1.9	0.9
Wears glasses or contact lenses	0.7	0.8	5.0	0.1	0.1	0.6	2.2	1.3	0.6	0.5	-0.1	-0.1	1.0	-0.0
Type 2 Diabetes (T2D) (2018)	0.6	1.2	4.3	0.3	1.6	0.5	1.0	1.3	0.7	1.0	-0.0	0.2	2.1	1.2
Qualifications: CSEs or equivalent	0.6	0.8	1.6	0.9	0.8	0.8	0.5	0.3	0.8	1.2	1.0	1.2	1.3	-0.1
Allergy	0.6	1.4	3.1	-0.7	-1.1	-0.9	-1.7	-1.5	-1.4	-1.3	-0.8	-1.2	-1.3	-0.4
Impedance of arm (left)	0.6	2.9	9.2	-1.2	-0.7	-1.6	-3.0	-1.2	-2.8	-2.1	-1.0	-1.1	-1.6	-0.8
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.1	1.1	1.8	1.2	1.0	0.3	0.3	0.7	1.1	0.9	0.6	0.5
Glaucoma (self-reported)	0.6	0.7	1.8	-0.7	-0.4	-0.8	-1.4	-0.9	-0.8	-0.8	-0.8	-0.8	-1.1	-0.2
Number of children fathered	0.6	0.7	1.0	-1.0	-1.0	-0.7	-0.7	-0.6	-0.2	-0.7	-1.0	-0.9	-1.0	-0.9
Whole body fat mass	0.6	2.5	8.8	0.9	0.3	1.4	1.8	3.0	2.3	1.4	0.9	0.9	0.6	1.7
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.0	-0.9	0.1	-0.8	-0.3	-0.9	-0.4	-0.8	-1.1	-1.2	-1.4	-0.6
Knee pain experienced in last month	0.6	1.0	3.7	0.5	1.3	0.6	1.9	0.4	1.7	1.1	0.5	0.5	0.6	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.3	-0.7	1.0	-1.2	-1.5	-1.1	-1.0	-1.0	-0.7	-0.8	-0.3	-0.5
Osteoarthritis (self-reported)	0.6	0.7	2.1	-1.4	-0.9	-1.3	-0.1	-0.4	-0.6	-0.6	-1.0	-0.8	-0.6	-0.7
Medication: Paracetamol	0.6	0.9	1.7	-1.1	-1.0	-1.2	-1.3	-0.9	-0.6	-0.8	-1.1	-1.0	-0.7	-0.7
Alzheimer’s Disease (in mother)	0.5	0.5	1.3	-0.6	-0.3	-0.4	-0.1	-0.8	-0.3	-1.0	-1.0	-1.1	-0.3	-1.1
HbA1C	0.5	0.6	1.7	0.6	0.3	0.9	0.8	1.3	1.1	0.8	0.5	0.5	0.3	0.6
Systolic Blood Pressure	0.5	2.6	4.4	2.0	2.1	1.6	1.2	0.6	1.0	1.6	2.1	2.0	1.5	0.8
Medication for hormone replacement therapy	0.5	0.5	2.5	-0.6	-1.6	-0.1	0.7	-0.7	-0.9	-0.4	-0.5	-0.6	-0.8	0.0
Fed-up feelings	0.5	0.9	2.0	1.1	0.6	0.8	0.0	0.7	1.4	1.0	1.2	1.1	0.5	0.8
Illnesses of siblings	0.5	0.8	2.2	0.8	1.5	0.9	0.6	0.4	0.8	0.8	0.6	0.7	1.3	-0.7
Happiness	0.5	0.6	2.2	-0.3	-0.7	-0.4	-1.5	-0.8	-1.2	-0.8	-0.2	-0.2	-0.6	0.3
Mouth/teeth dental problems: Dentures	0.5	0.9	2.1	-1.4	-0.4	-1.2	-0.7	-0.8	0.0	-0.9	-1.5	-1.3	-0.2	-0.2
Tense / ‘highly strung’	0.5	0.8	2.3	0.6	1.5	1.2	1.2	0.8	1.2	0.6	0.7	0.6	-0.0	0.1
Birth weight	0.5	1.0	1.6	-1.2	-0.8	-0.9	0.6	-0.8	-0.6	-1.3	-1.2	-1.3	-1.1	-1.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.3	-0.9	-0.9	-0.6	0.1	-0.6	0.3	-0.7	-1.1	-1.1	-0.7	-0.8
Migraine (self-reported)	0.5	0.6	1.7	-0.8	-1.3	-0.7	-0.2	-0.8	-0.6	-0.6	-0.7	-0.5	-0.6	-1.3
Medication: Aspirin	0.5	0.7	1.6	-0.5	-0.5	-1.1	-0.4	-0.9	-1.3	-0.9	-0.7	-0.8	-1.1	-0.6
Illnesses of siblings: Diabetes	0.5	0.6	2.2	0.2	-1.0	0.7	1.2	1.1	0.1	0.3	0.1	-0.0	0.4	1.5
Medication: Aspirin	0.5	0.7	1.3	-0.7	-0.8	-1.2	0.0	-0.8	-1.0	-0.8	-0.9	-1.0	-0.8	-0.5
Eye problems/disorders: Glaucoma	0.5	0.6	1.4	-0.9	-0.2	-0.6	-1.0	-0.4	-0.6	-0.8	-0.8	-0.8	-1.2	-0.2
Average weekly beer plus cider intake	0.5	0.8	3.2	-0.9	-1.8	-0.2	-1.1	-0.6	0.8	-0.6	-0.8	-0.8	-0.7	-0.2
Risk taking	0.5	0.7	2.2	-0.7	-0.7	-0.3	0.3	-0.6	-0.3	-0.8	-0.8	-0.8	-1.5	-1.3
Leg fat mass (left)	0.5	1.9	6.1	0.7	0.3	1.1	1.7	2.5	2.3	1.3	0.7	0.7	0.5	1.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	4.0	-1.2	0.3	-1.0	-0.5	-0.7	-2.0	-1.6	-1.0	-1.1	-1.6	-0.1
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.4	0.8	1.4	0.8	0.3	1.4	-0.2	0.3	1.1	0.9	0.4	1.6
Ovarian Cancer	0.4	0.6	1.3	0.9	0.8	0.9	1.2	0.5	0.7	0.7	0.7	0.7	0.5	0.2
Prostate Cancer	0.4	0.6	2.6	0.4	0.3	1.0	1.6	0.6	-0.4	0.3	0.6	0.6	-0.1	1.0
Neuroticism (2016)	0.4	0.6	1.4	1.0	0.0	0.8	1.2	0.3	-0.7	0.5	1.1	1.0	0.3	0.9
Blood Eosinophil Count	0.4	2.9	8.6	-1.9	-2.9	-1.1	-0.3	-0.1	-2.2	-1.7	-1.7	-1.4	-2.4	-0.7
BMI	0.4	2.2	6.2	-1.9	-2.5	-1.1	0.6	-0.3	0.2	-1.1	-2.0	-1.9	-1.8	-0.8
Cardiovascular Disease	0.4	1.2	4.6	-0.9	0.4	-0.6	0.5	-1.4	-2.1	-1.2	-1.0	-1.0	-0.7	-1.1
Townsend deprivation index at recruitment	0.4	0.6	3.6	-0.2	-0.5	-0.8	-1.9	-0.9	-0.4	-0.3	-0.0	0.0	-0.7	-0.3
Current tobacco smoking	0.4	0.7	2.9	-0.5	0.9	-1.0	-1.7	-0.8	0.2	-0.5	-0.4	-0.3	-0.3	-1.2
Medication: Levothyroxine sodium	0.4	0.6	1.6	0.6	0.2	1.0	1.1	0.9	0.5	1.1	0.4	0.6	1.3	0.4
Number of incorrect matches in round	0.4	0.7	2.9	-0.3	-1.7	-0.8	-1.2	-0.4	-1.1	-0.5	-0.2	-0.2	-0.8	0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.0	0.9	0.6	0.7	0.9	0.4	0.9	0.9	0.9	1.0	0.6	0.2
Fluid intelligence score	0.4	0.8	2.9	0.8	0.9	0.7	0.8	1.1	-0.0	0.4	1.0	0.8	0.2	1.7
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.0	0.5	2.0	0.9	1.8	0.3	-0.1	0.3	0.4	0.4	0.8	-0.3
Exposure to tobacco smoke at home	0.4	0.4	1.7	-0.7	-1.3	-0.7	-0.7	-0.5	-0.3	-0.4	-0.5	-0.3	-1.0	-0.1
Number of full brothers	0.4	0.4	1.8	0.7	0.6	0.4	-0.1	0.6	1.3	0.9	0.6	0.7	0.4	-0.2
Emphysema/chronic bronchitis	0.4	0.5	1.7	0.5	1.3	0.7	0.3	1.1	0.7	0.5	0.6	0.7	0.5	-0.0
Medication for pain relief, constipation, heartburn	0.4	0.7	2.8	0.6	0.8	1.3	1.7	0.5	0.8	0.4	0.3	0.3	0.6	0.1
Heart disease (mother)	0.4	0.5	1.3	-0.4	-0.7	-0.7	0.5	-1.1	-0.7	-0.4	-0.5	-0.5	-0.1	-1.1
Leg fat mass (right)	0.4	1.7	5.7	0.5	0.3	1.0	1.6	2.4	2.2	1.2	0.6	0.6	0.5	1.2
Family relationship satisfaction	0.4	0.5	0.8	0.6	0.0	0.7	-0.4	0.7	0.7	0.9	0.8	0.9	0.9	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.2	-0.9	0.3	-0.8	-0.6	-0.5	-0.4	-0.6	-1.1	-1.1	-0.5	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.9	-0.6	-1.7	-0.5	0.2	-0.2	-0.0	-0.3	-0.8	-0.9	0.3	0.6
Loneliness, isolation	0.4	0.5	1.4	-0.8	-0.6	-0.5	-0.6	-0.8	-0.7	-0.7	-0.6	-0.6	-0.8	-1.2
Qualifications: nursing, teaching	0.4	0.6	2.5	-0.6	-0.0	0.1	1.6	-0.3	-1.1	-0.5	-0.9	-0.9	-0.5	-0.9
Medication: Gliclazide	0.4	0.5	0.9	-0.7	-0.6	-0.6	-0.6	-0.5	-1.0	-0.7	-1.0	-0.9	-0.4	-0.1
Miserableness	0.4	0.6	1.9	0.9	1.4	0.5	-0.0	0.5	0.6	0.6	1.1	1.1	0.7	0.4
Number of operations (self-reported)	0.4	0.6	1.8	0.7	1.1	0.7	0.4	0.5	1.3	0.7	0.7	0.8	0.5	-0.6
Basal cell carcinoma (self-reported)	0.4	0.5	0.9	-0.8	-0.7	-0.5	0.8	-0.6	-0.3	-0.5	-0.9	-0.9	-0.2	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.2	-0.9	-0.8	-0.9	-0.2	-1.1	-0.5	-0.6	-0.7	-0.6	-0.9	-0.8
Heart disease (siblings)	0.4	0.5	1.5	-0.5	-1.1	-0.5	-1.2	-0.4	-0.4	-0.6	-0.5	-0.5	-1.0	0.0
Neuroticism (Nagel 2018)	0.3	0.6	1.1	0.6	1.1	0.8	0.7	0.6	0.9	0.8	0.9	0.9	1.0	0.2
Alzheimer’s Disease (in father)	0.3	0.3	1.3	0.0	-0.5	0.3	1.2	0.3	0.7	0.2	-0.3	-0.3	0.8	-0.5
Irritable Bowel Disease (IBD)	0.3	0.8	2.3	-1.1	-0.5	-1.5	-1.0	0.0	-1.3	-0.5	-1.1	-0.8	-0.1	0.1
Body Mass Index (BMI) (2010)	0.3	0.4	3.3	0.1	0.7	0.4	1.8	0.2	0.2	0.4	0.1	0.2	0.5	-0.1
Heel T-Score	0.3	2.2	4.0	-1.6	1.1	-1.8	-1.7	-0.7	-1.7	-1.6	-1.5	-1.2	-2.0	-0.4
Average weekly spirits intake	0.3	0.3	0.9	0.4	-0.8	0.4	0.5	0.7	0.5	0.6	0.2	0.3	0.3	0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.4	-0.5	-0.5	-0.2	-0.5	-0.7	0.0	-0.6	-0.6	-0.6	-0.5	-1.2
Medication: Metformin	0.3	0.4	1.4	0.1	1.2	0.3	0.7	0.7	0.3	0.5	-0.0	0.1	1.0	0.2
Pack years adult smoking proportion	0.3	0.5	2.6	0.1	0.2	0.0	-0.9	0.9	1.6	0.4	0.2	0.2	0.2	1.0
Supplements: Glucosamine	0.3	0.4	1.4	0.5	0.3	0.4	1.2	0.8	0.4	0.7	0.5	0.5	0.7	0.3
Had other major operations	0.3	0.4	2.7	-0.4	-0.1	-0.1	0.4	-0.7	0.8	-0.1	-0.5	-0.3	-0.0	-1.6
Father’s age at death	0.3	0.4	1.3	0.2	-0.5	0.3	0.7	1.0	0.9	0.3	0.0	-0.0	0.4	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.9	-0.9	0.3	-0.7	0.0	-0.3	-0.9	-0.7	-0.9	-0.8	-0.3	-0.2
Lung cancer (father)	0.3	0.3	1.4	0.1	0.0	-0.8	-1.2	-0.9	-0.4	-0.4	-0.0	-0.1	-0.2	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.5	0.6	0.2	1.0	1.1	0.7	0.0	0.9	0.4	0.6	1.2	0.5
Leg fat percentage (right)	0.3	1.0	2.0	-1.3	-1.0	-1.1	-0.8	0.2	0.2	-0.9	-1.3	-1.3	-1.4	-0.5
Wheeze or whistling in the chest in last year	0.3	0.6	1.3	0.8	0.4	0.6	0.5	1.1	0.6	0.8	0.8	1.0	0.4	1.1
Back pain experienced in last month	0.3	0.5	1.7	-0.6	-0.4	-0.3	-0.2	-0.7	-0.3	-1.0	-0.7	-0.8	-1.3	-0.6
Smoking status: Current	0.3	0.5	1.7	-0.5	0.7	-1.0	-1.3	-0.7	0.0	-0.5	-0.4	-0.4	-0.2	-1.0
Medication: Bendroflumethiazide	0.3	0.4	2.2	-0.5	0.3	-0.8	0.4	-0.3	-1.5	-0.4	-0.7	-0.6	-0.4	-0.2
Pack years of smoking	0.3	0.4	1.8	0.0	0.3	-0.1	-0.7	0.9	1.3	0.3	0.0	0.1	0.0	1.0
Depressed Affect (Nagel 2018)	0.2	0.4	0.8	0.7	0.6	0.7	0.5	0.6	0.8	0.6	0.9	0.9	0.6	0.2
Crohns Disease (2017)	0.2	0.5	1.5	0.4	0.1	-0.2	-1.1	1.2	-0.6	0.4	0.4	0.6	0.6	1.2
Age at First Birth	0.2	0.4	1.1	0.5	-0.1	0.6	0.3	1.0	0.6	0.3	0.5	0.5	0.5	0.9
Mean Putamen Volume	0.2	0.2	1.1	0.2	0.5	-0.2	-0.7	-0.2	-1.1	-0.2	0.4	0.4	-0.1	0.4
Lupus	0.2	0.2	1.3	-0.3	-0.8	-0.0	-0.5	0.2	0.0	-0.5	-0.1	-0.2	-1.1	-0.1
Smoking Status	0.2	0.5	1.5	0.1	1.0	0.1	0.7	0.5	1.2	0.8	0.2	0.4	0.8	-0.5
Neuroticism	0.2	0.5	1.3	0.8	0.5	0.9	-0.3	0.6	0.0	0.6	1.1	1.1	0.3	0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	-0.5	-0.8	-0.3	-0.9	0.2	-0.2	-0.1	-0.6	-0.6	-0.1	0.4
Supplements: Zinc	0.2	0.2	0.8	-0.3	0.8	-0.3	0.4	0.1	0.2	-0.0	-0.2	-0.1	0.1	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	0.6	0.2	0.7	0.7	0.5	0.8	0.5	0.6	0.5	0.3	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	3.6	-0.4	1.9	-0.1	-0.3	0.5	0.3	-0.3	-0.6	-0.5	-0.3	0.9
High blood pressure	0.2	0.5	1.3	-0.6	0.2	-0.6	0.3	-0.9	-1.1	-0.7	-0.6	-0.5	-0.5	-0.9
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.0	0.1	1.0	0.1	0.3	0.7	0.5	0.6	0.3	0.5	1.0	-0.4
Waist circumference	0.2	0.8	3.5	-0.1	0.4	0.6	1.5	1.9	1.1	0.6	0.0	0.2	-0.0	0.7
Past tobacco smoking	0.2	0.3	0.9	-0.2	0.4	-0.2	-1.0	-0.5	-0.9	-0.7	-0.3	-0.4	-0.5	-0.6
Hearing difficulty/problems with background noise	0.2	0.3	0.9	-0.0	1.0	0.0	0.5	0.8	-0.6	0.2	0.1	0.3	0.6	0.8
Financial difficulties in last 2 years	0.2	0.2	1.2	-0.2	-1.1	-0.1	-0.3	-0.3	0.3	-0.0	0.0	0.2	-0.5	-0.9
Heart attack	0.2	0.2	0.6	0.1	-0.1	0.0	0.5	-0.7	-0.6	-0.4	-0.0	-0.1	-0.7	-0.8
Neuroticism score	0.2	0.4	1.0	0.7	0.8	0.6	-0.5	0.1	0.3	0.4	1.0	1.0	0.3	0.1
Hip circumference	0.2	0.7	2.0	-1.0	-1.2	-0.6	0.6	0.5	-0.0	-0.7	-1.0	-1.0	-1.4	-0.2
Prospective memory result	0.2	0.2	1.3	-0.2	-1.2	-0.4	-0.6	-0.5	-0.2	-0.4	-0.2	-0.3	-0.2	0.1
Illnesses of mother	0.2	0.2	0.9	0.2	0.8	0.2	0.4	0.3	0.6	0.6	0.2	0.2	1.0	0.1
Hair/balding pattern: Pattern 4	0.2	0.6	2.2	-0.0	-1.3	0.2	1.5	0.7	0.6	0.5	-0.4	-0.5	0.6	1.0
Medication: Paracetamol	0.2	0.3	0.8	-0.6	0.1	-0.6	-0.9	-0.2	-0.2	-0.3	-0.5	-0.4	-0.3	-0.7
High blood pressure (siblings)	0.2	0.3	1.1	-0.3	-1.1	-0.4	0.4	-0.2	-0.6	-0.3	-0.3	-0.4	-0.8	0.2
Body fat percentage	0.2	0.9	1.9	-1.1	-1.4	-0.8	-0.5	0.9	0.1	-0.8	-1.0	-1.0	-1.4	0.0
Neck or shoulder pain in last month	0.2	0.2	1.0	0.3	0.6	0.1	1.0	0.3	0.4	0.5	0.3	0.4	0.1	0.4
Smoking status: Previous	0.2	0.3	1.9	-0.0	-0.7	0.2	1.4	0.3	0.7	0.7	0.1	0.2	0.4	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.0	0.2	0.8	0.1	0.7	-0.0	0.2	0.4	0.4	0.5	1.0	0.2
Financial situation satisfaction	0.2	0.3	0.5	0.3	-0.4	0.6	0.2	0.5	-0.3	0.6	0.7	0.7	0.5	0.7
Alcohol drinker status: Never	0.2	0.3	0.4	-0.6	0.3	-0.5	-0.5	-0.6	-0.6	-0.5	-0.6	-0.5	-0.3	-0.5
Leg fat percentage (left)	0.2	0.6	1.4	-1.0	-0.9	-0.8	-0.5	0.5	0.5	-0.6	-1.0	-1.0	-1.2	-0.3
Irritability	0.2	0.3	0.9	-0.4	0.1	-0.2	0.3	-0.9	-0.5	-0.5	-0.2	-0.2	-0.9	-0.9
Commuting to job workplace: Cycle	0.2	0.3	0.7	0.5	0.5	0.2	-0.3	0.6	0.2	0.4	0.8	0.8	0.5	0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.9	0.5	-0.1	0.5	-0.4	1.0	1.4	0.8	0.6	0.5	0.6	0.8
Pain experienced in last month	0.2	0.3	0.6	-0.5	-0.2	-0.7	-0.8	-0.4	-0.7	-0.5	-0.5	-0.4	0.1	-0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.6	-0.0	-0.2	-0.1	0.3	-0.7	-0.8	-0.5	-0.1	-0.2	-0.7	-0.7
Alcohol drinker status: Previous	0.2	0.2	0.5	-0.3	-0.1	-0.6	-0.6	-0.7	0.4	-0.4	-0.6	-0.6	-0.5	-0.1
Depression (Nagel 2018)	0.1	0.2	0.8	-0.3	-0.9	-0.2	-0.2	-0.3	-0.4	-0.4	-0.4	-0.4	-0.5	-0.5
Worry (Nagel 2018)	0.1	0.3	1.4	-0.4	-0.0	-0.1	-1.2	-0.5	-0.3	-0.5	-0.2	-0.2	-0.2	-0.8
HDL Cholesterol	0.1	0.2	0.4	0.4	-0.6	0.0	-0.4	0.0	-0.4	0.1	0.6	0.5	0.1	0.2
Schizophrenia (2014)	0.1	0.3	0.9	0.2	1.0	-0.1	-0.8	-0.1	-0.8	0.4	0.4	0.6	0.2	-0.1
Triglycerides	0.1	0.2	0.6	0.3	0.1	0.4	0.3	0.4	0.8	0.6	0.4	0.4	0.4	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.1
Allergy or Eczema	0.1	0.2	0.6	-0.2	0.6	-0.0	0.4	0.7	0.7	0.6	0.0	0.4	0.7	-0.4
Hypothyroidism (self reported)	0.1	0.1	0.6	0.1	0.2	0.5	0.6	0.3	-0.3	0.4	-0.0	0.2	0.7	0.2
Sensitivity / hurt feelings	0.1	0.2	0.8	0.2	0.5	-0.3	-0.9	-0.2	0.0	0.2	0.5	0.6	0.4	0.0
Systolic blood pressure, automated reading	0.1	0.3	0.9	0.8	0.5	0.5	0.4	0.1	0.4	0.4	1.0	0.9	-0.2	0.2
Angina	0.1	0.1	0.3	0.1	-0.5	-0.1	-0.1	-0.5	-0.2	-0.1	-0.4	-0.5	-0.1	-0.3
Trunk fat percentage	0.1	0.5	2.5	-0.4	-0.9	-0.1	0.0	1.6	0.6	-0.2	-0.3	-0.4	-0.7	0.7
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	-0.3	0.2	0.0	-0.6	0.4	0.4	0.2	-0.3	-0.1	0.3	0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	-0.0	0.4	-0.0	0.2	0.6	0.3	0.5	-0.0	0.2	0.4	0.2
Medication: Atenolol	0.1	0.1	0.3	-0.5	0.1	-0.5	0.1	-0.5	0.1	-0.4	-0.5	-0.3	-0.3	-0.0
Alcohol usually taken with meals	0.1	0.1	0.3	-0.0	-0.5	-0.3	0.2	-0.5	-0.5	-0.1	-0.2	-0.3	0.0	-0.4
Medication: Ramipril	0.1	0.1	0.9	-0.0	-0.1	-0.2	-0.9	-0.0	-0.6	-0.3	-0.1	-0.2	-0.4	0.2
Worrier / anxious feelings	0.1	0.2	0.6	0.5	0.4	0.4	0.2	0.2	0.3	0.4	0.5	0.5	0.8	0.2
Arm fat mass (right)	0.1	0.5	2.0	-0.6	-0.9	-0.0	0.6	1.4	0.8	-0.1	-0.5	-0.5	-0.9	0.4
Length of working week for main job	0.1	0.1	0.3	-0.2	-0.5	-0.1	0.5	0.3	-0.0	0.3	-0.2	-0.1	-0.1	-0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	-0.6	-0.3	-0.4	0.1	-0.4	0.2	-0.2	-0.3	-0.2	-0.6	-0.5
Blood clot in the leg (DVT)	0.1	0.1	0.3	-0.4	-0.4	-0.4	0.3	-0.5	0.0	-0.1	-0.2	-0.1	-0.3	-0.4
Medication: Amlodipine	0.1	0.2	0.9	-0.0	-0.2	0.1	0.5	0.3	-0.6	-0.2	0.0	-0.0	0.2	1.0
Comparative body size at age 10	0.1	0.2	1.0	-0.6	-1.0	-0.3	0.4	0.0	-0.1	-0.2	-0.2	-0.1	-0.4	-0.7
Health satisfaction	0.1	0.1	0.8	-0.1	0.8	0.2	0.0	-0.1	-0.9	-0.3	-0.1	-0.2	-0.0	-0.1
Angina (self-reported)	0.1	0.1	0.3	0.6	-0.4	0.4	0.5	-0.1	0.2	0.3	0.1	-0.0	0.2	0.2
Number of full sisters	0.1	0.1	0.4	-0.2	0.6	-0.3	-0.5	-0.2	0.4	0.1	-0.0	0.1	-0.1	-0.2
Had major operations	0.1	0.1	0.4	0.2	-0.3	-0.3	-0.7	0.0	-0.3	-0.3	0.2	0.1	-0.7	0.0
Age at last live birth	0.1	0.2	0.7	-0.2	0.7	-0.3	0.2	-0.3	0.1	-0.3	-0.3	-0.2	0.4	-0.8
Hypertension (Self-reported)	0.1	0.3	1.2	-0.4	0.5	-0.5	0.6	-0.8	-1.1	-0.5	-0.4	-0.4	-0.3	-0.5
Mood swings	0.1	0.3	0.8	0.4	0.2	0.6	0.9	0.5	0.4	0.3	0.5	0.5	0.4	0.5
Eye problems/disorders: Cataract	0.1	0.2	0.7	-0.2	-0.2	0.1	-0.7	0.7	0.8	-0.2	-0.2	-0.2	-0.2	-0.2
Mineral and other dietary supplements	0.1	0.2	0.5	-0.0	-0.6	0.3	-0.7	-0.3	-0.0	-0.1	0.2	0.4	-0.7	-0.5
Breast cancer (self-reported)	0.1	0.1	0.5	0.1	0.6	0.2	-0.7	0.5	0.4	0.2	0.1	0.1	0.4	0.2
Arm fat mass (left)	0.1	0.6	2.0	-0.6	-1.1	0.0	0.7	1.4	0.9	-0.1	-0.5	-0.5	-0.9	0.5
Average weekly champagne plus white wine intake	0.1	0.1	0.4	0.0	-0.0	-0.2	0.5	0.0	-0.4	-0.0	-0.3	-0.3	0.7	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.8	0.3	0.9	-0.1	0.4	-0.1	-0.2	-0.1	0.0	-0.3	0.6	-0.1
Ever smoked	0.1	0.2	0.8	-0.1	-0.6	-0.0	0.9	0.3	0.9	0.4	0.2	0.3	0.1	0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.5	-0.1	-0.1	-0.1	0.1	0.2	0.2	-0.1	-0.0	0.0	0.3	0.7
Age started oral contraceptive pill	0.1	0.1	0.4	-0.1	0.7	-0.1	0.2	0.3	0.1	0.3	0.2	0.3	-0.1	-0.2
Diastolic blood pressure, automated reading	0.1	0.3	1.0	0.0	-0.9	0.3	1.0	0.2	0.2	-0.1	0.3	0.3	-0.6	-0.3
Supplements: Calcium	0.1	0.2	0.9	-0.2	0.7	-0.2	-0.1	0.2	0.1	0.1	-0.3	-0.2	1.0	-0.2
Impedance of whole body	0.1	0.7	2.6	0.8	1.5	0.3	-1.6	0.6	-0.5	0.0	0.8	0.7	0.6	0.4
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0
Hair Pigment	0.0	1.0	3.3	-0.7	-1.2	-0.8	-0.7	-0.9	-1.0	-1.1	-0.7	-0.9	-1.8	-0.8
Time employed in main current job	0.0	0.1	0.2	-0.2	-0.2	0.0	0.3	-0.1	-0.5	0.1	-0.0	0.1	0.4	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.2	-0.1	0.4	-0.3	-0.2	-0.0	0.2	-0.1	-0.0	0.1	-0.2	-0.2
Peak expiratory flow (PEF)	0.0	0.0	0.3	0.2	0.5	0.0	0.0	-0.1	-0.2	-0.1	-0.0	-0.1	0.3	-0.2
Pulse wave reflection index	0.0	0.0	0.2	-0.2	-0.4	-0.1	0.2	-0.0	0.1	-0.1	-0.1	-0.1	-0.1	-0.5
Headache pain in last month	0.0	0.1	0.2	0.3	-0.1	0.4	0.1	0.2	-0.3	0.3	0.3	0.2	-0.1	-0.2
Medication: Lisinopril	0.0	0.1	0.1	0.3	0.1	0.2	-0.1	-0.1	0.4	0.3	0.2	0.2	0.4	0.0

Hub : Genes

PARP10

Models

Trait associations