Best TWAS P=5.4e-13 · Best GWAS P=9.53e-14 conditioned to 0.0406
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PCP4L1 | 0.06 | 0.06 | lasso | 3 | 0.05 | 3.2e-07 | 4.8 | 5.2 | 2.6e-07 | 0.52 | 0.79 | 0.12 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | PPOX | 0.14 | 0.14 | lasso | 4 | 0.13 | 6.0e-10 | 7.3 | 7.2 | 5.4e-13 | 0.93 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | B4GALT3 | 0.31 | 0.28 | enet | 16 | 0.30 | 2.0e-22 | 7.3 | 6.2 | 5.7e-10 | 0.90 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | ADAMTS4 | 0.35 | 0.22 | lasso | 7 | 0.26 | 1.5e-19 | 7.3 | 7.2 | 7.5e-13 | 0.92 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Nerve Tibial | B4GALT3 | 0.14 | 0.04 | lasso | 3 | 0.04 | 1.5e-03 | 7.3 | 5.3 | 1.4e-07 | 0.82 | 0.00 | 0.97 | FALSE |
| 6 | METSIM | Adipose | FCER1G | 0.15 | 0.11 | enet | 15 | 0.12 | 6.3e-17 | 7.4 | 6.5 | 7.9e-11 | 0.93 | 0.00 | 1.00 | FALSE |
| 7 | NTR | Blood | FCER1G | 0.17 | 0.14 | lasso | 6 | 0.16 | 3.4e-49 | 7.4 | 6.8 | 1.3e-11 | 0.96 | 0.00 | 1.00 | FALSE |
| 8 | YFS | Blood | FCER1G | 0.46 | 0.42 | lasso | 8 | 0.45 | 4.2e-166 | 7.4 | 7.1 | 1.1e-12 | 0.97 | 0.00 | 1.00 | FALSE |