[Hub]/) : Traits : Allergy or Eczema : ← →

chr1:153,225,886-156,572,984

Best TWAS P=1.86e-12 · Best GWAS P=2.46e-15 conditioned to 2.69e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CRTC2 0.04 0.00 lasso 3 0.01 6.7e-02 2.38 -5.8 5.3e-09 -0.45 0.05 0.60 FALSE
2 GTEx Brain Cerebellar Hemisphere DCST2 0.45 0.10 lasso 6 0.16 6.6e-05 3.13 -5.2 2.0e-07 0.09 0.01 0.96 FALSE
3 GTEx Colon Sigmoid IL6R 0.22 0.08 lasso 4 0.05 9.2e-03 6.99 -6.2 7.5e-10 -0.93 0.03 0.71 FALSE
4 GTEx Colon Transverse SLC39A1 0.11 -0.01 lasso 6 -0.01 7.9e-01 -0.44 5.3 1.2e-07 0.59 0.06 0.28 FALSE
5 GTEx Colon Transverse IL6R 0.18 0.06 lasso 3 0.06 9.2e-04 6.76 -6.5 9.8e-11 -0.92 0.10 0.78 FALSE
6 GTEx Esophagus Muscularis IL6R 0.10 0.00 enet 15 0.00 5.3e-01 7.14 -6.9 4.3e-12 -0.67 0.01 0.87 FALSE
7 GTEx Muscle Skeletal RIT1 0.06 0.03 enet 8 0.03 3.6e-04 5.05 -5.3 1.1e-07 -0.03 0.02 0.97 FALSE
8 GTEx Skin Sun Exposed Lower leg ADAM15 0.14 0.09 lasso 4 0.08 6.1e-07 -5.69 5.2 2.7e-07 -0.03 0.00 1.00 FALSE
9 GTEx Whole Blood SLC39A1 0.13 0.01 enet 19 0.05 1.6e-05 1.14 5.3 1.5e-07 0.28 0.25 0.08 FALSE
10 GTEx Whole Blood C1orf43 0.10 0.00 enet 37 0.00 2.8e-01 1.14 5.4 6.6e-08 0.24 0.05 0.11 TRUE
11 METSIM Adipose RIT1 0.04 0.06 lasso 4 0.05 1.9e-08 5.00 -5.3 1.1e-07 -0.03 0.03 0.97 FALSE
12 YFS Blood IL6R 0.04 0.04 lasso 3 0.04 5.1e-12 6.99 -7.0 1.9e-12 -0.95 0.01 0.99 TRUE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZBTB7B 0.05 0.06 lasso 2 0.05 1.8e-06 -5.69 5.7 1.3e-08 -0.04 0.00 1.00 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma MSTO2P 0.04 0.00 enet 9 0.02 4.2e-03 3.93 -5.5 3.8e-08 0.00 0.00 0.02 TRUE
15 The Cancer Genome Atlas Skin Cutaneous Melanoma IL6R 0.12 0.04 blup 57 0.11 6.0e-04 7.92 5.3 1.3e-07 0.86 0.01 0.87 FALSE