[Hub]/) : Traits : Allergy or Eczema : ← →

chr4:122,377,715-124,935,698

Best TWAS P=4.12e-47 · Best GWAS P=3.57e-38 conditioned to 0.176

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1109 0.09 0.08 bslmm 390 0.08 8.9e-10 12.5 -8.9 5.4e-19 -0.68 0.08 0.92 FALSE
2 GTEx Artery Aorta KIAA1109 0.11 0.00 lasso 7 0.01 5.1e-02 12.8 -10.4 1.5e-25 -0.65 0.07 0.52 FALSE
3 GTEx Artery Tibial KIAA1109 0.16 0.07 lasso 6 0.05 5.1e-05 12.3 -11.9 1.3e-32 -0.79 0.05 0.92 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia KIAA1109 0.22 0.07 lasso 7 0.03 5.9e-02 12.3 -12.0 2.5e-33 -0.71 0.05 0.35 FALSE
5 GTEx Cells Transformed fibroblasts BBS12 0.10 0.02 lasso 6 0.02 7.2e-03 -5.4 -5.8 8.0e-09 -0.24 0.08 0.04 FALSE
6 GTEx Colon Transverse KIAA1109 0.25 -0.01 enet 16 0.00 4.1e-01 12.3 -12.7 4.7e-37 -0.92 0.02 0.77 TRUE
7 ROSMAP Brain Pre-frontal Cortex KIAA1109 0.08 0.08 lasso 7 0.07 2.5e-09 12.3 -12.0 3.0e-33 -0.79 0.08 0.92 FALSE
8 ROSMAP Brain Pre-frontal Cortex SPATA5 0.05 0.01 bslmm 485 0.01 1.2e-02 4.7 -9.0 1.9e-19 -0.12 0.16 0.06 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1109 0.03 0.03 lasso 1 0.02 1.2e-05 12.3 -12.3 5.6e-35 -0.77 0.17 0.73 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma KIAA1109 0.32 0.02 blup 45 0.02 7.4e-02 12.3 -14.4 4.1e-47 -0.51 0.01 0.45 TRUE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1109 0.05 0.05 enet 8 0.04 1.3e-05 12.3 -9.2 3.1e-20 -0.80 0.02 0.94 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1109 0.06 0.05 lasso 2 0.03 7.1e-05 12.3 -12.6 1.6e-36 -0.79 0.35 0.46 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma KIAA1109 0.05 0.04 enet 3 0.05 5.4e-06 12.3 -13.1 3.5e-39 -0.90 0.01 0.98 FALSE