[Hub]/) : Traits : Allergy or Eczema : ← →

chr5:108,927,715-111,770,880

Best TWAS P=3.17e-52 · Best GWAS P=2.88e-65 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TMEM232	0.08	0.05	lasso	4	0.05	1.6e-06	2.63	6.5	1.1e-10	0.10	0.92	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	WDR36	0.05	0.03	enet	13	0.01	1.0e-02	-3.07	-7.6	3.6e-14	0.44	0.15	0.39	FALSE
3	GTEx	Adipose Subcutaneous	WDR36	0.14	0.06	lasso	6	0.04	2.1e-04	-8.15	-5.4	6.3e-08	0.22	0.88	0.02	FALSE
4	GTEx	Adipose Visceral Omentum	WDR36	0.11	0.08	lasso	4	0.10	8.7e-06	-5.17	-7.0	2.3e-12	0.39	0.81	0.05	FALSE
5	GTEx	Artery Tibial	WDR36	0.11	0.05	lasso	5	0.07	3.2e-06	-5.17	-7.0	2.4e-12	0.42	0.87	0.02	FALSE
6	GTEx	Brain Cerebellar Hemisphere	WDR36	0.32	0.12	lasso	7	0.17	4.8e-05	-4.64	-7.0	2.0e-12	0.33	0.12	0.13	TRUE
7	GTEx	Brain Cerebellum	WDR36	0.26	0.22	lasso	4	0.27	1.5e-08	-4.64	-5.5	4.9e-08	0.30	0.40	0.11	FALSE
8	GTEx	Breast Mammary Tissue (Male)	WDR36	0.04	0.15	lasso	4	0.08	6.6e-03	5.32	-5.3	1.1e-07	0.35	0.04	0.10	FALSE
9	GTEx	Liver	WDR36	0.32	-0.01	enet	19	0.03	5.4e-02	-3.59	-9.4	4.8e-21	0.64	0.06	0.31	FALSE
10	GTEx	Muscle Skeletal	WDR36	0.08	0.05	lasso	4	0.03	3.0e-04	5.32	-6.2	4.4e-10	0.41	0.40	0.22	FALSE
11	GTEx	Nerve Tibial	WDR36	0.24	0.04	enet	30	0.07	9.5e-06	-5.17	-5.2	1.9e-07	0.31	0.71	0.03	FALSE
12	GTEx	Nerve Tibial	SLC25A46	0.15	0.01	enet	18	0.07	1.2e-05	9.45	-7.8	4.9e-15	0.00	0.52	0.02	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	WDR36	0.17	0.09	lasso	6	0.08	2.6e-05	-7.98	-7.8	4.7e-15	0.44	0.66	0.25	FALSE
14	GTEx	Skin Sun Exposed Lower leg	WDR36	0.13	0.03	lasso	9	0.09	8.9e-08	-7.98	-6.9	5.3e-12	0.41	0.78	0.19	FALSE
15	GTEx	Spleen	SLC25A46	0.25	0.00	enet	6	0.02	1.3e-01	9.44	-8.7	2.4e-18	0.01	0.07	0.06	TRUE
16	GTEx	Testis	WDR36	0.61	0.37	lasso	10	0.34	5.7e-16	-7.97	-10.0	1.9e-23	0.57	1.00	0.00	FALSE
17	METSIM	Adipose	CAMK4	0.05	0.01	bslmm	518	0.03	8.3e-05	9.52	10.4	3.7e-25	-0.61	0.03	0.90	FALSE
18	METSIM	Adipose	TMEM232	0.04	0.06	lasso	8	0.06	9.8e-09	8.74	8.6	5.7e-18	0.08	1.00	0.00	FALSE
19	METSIM	Adipose	TSLP	0.16	0.18	lasso	7	0.18	8.5e-26	-15.24	15.1	2.0e-51	-0.92	0.30	0.70	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	TSLP	0.13	0.08	enet	14	0.09	4.1e-11	-14.29	12.2	4.5e-34	-0.73	1.00	0.00	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	CAMK4	0.10	0.03	lasso	4	0.04	7.8e-06	9.31	-10.1	5.6e-24	0.59	0.91	0.07	TRUE
22	ROSMAP	Brain Pre-frontal Cortex	STARD4-AS1	0.07	0.02	enet	19	0.03	5.0e-05	-0.57	-6.3	3.3e-10	0.39	0.06	0.82	FALSE
23	YFS	Blood	SLC25A46	0.03	0.02	enet	12	0.02	9.5e-07	9.45	-13.3	2.9e-40	0.25	0.95	0.00	TRUE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CAMK4	0.04	0.04	blup	159	0.01	3.6e-02	7.40	-6.4	1.9e-10	0.14	0.26	0.04	TRUE
25	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TMEM232	0.08	0.06	blup	158	0.07	6.4e-07	8.78	8.2	2.6e-16	0.08	0.98	0.00	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	TSLP	0.03	0.03	lasso	2	0.03	5.5e-07	-15.25	13.4	1.0e-40	-0.84	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	TMEM232	0.13	0.07	blup	161	0.11	1.0e-06	8.85	5.9	2.8e-09	0.09	0.95	0.00	TRUE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	TSLP	0.08	0.01	blup	39	0.03	5.4e-03	-14.50	12.4	4.7e-35	-0.78	0.01	0.74	FALSE
29	The Cancer Genome Atlas	Esophageal Carcinoma	TMEM232	0.17	0.16	lasso	2	0.13	7.5e-05	7.33	7.2	8.3e-13	0.09	0.68	0.02	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM232	0.07	0.03	blup	162	0.08	6.6e-09	2.49	5.7	1.2e-08	0.10	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TSLP	0.03	0.00	enet	7	0.01	3.8e-02	-12.26	9.6	8.8e-22	-0.64	0.02	0.42	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM232	0.07	0.12	lasso	2	0.12	4.7e-13	7.33	7.2	6.0e-13	0.10	1.00	0.00	TRUE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TSLP	0.05	0.02	blup	39	0.02	7.9e-04	-14.50	12.4	1.8e-35	-0.77	0.04	0.82	FALSE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM232	0.15	0.12	lasso	2	0.16	2.2e-09	8.83	8.1	7.0e-16	0.09	1.00	0.00	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	TMEM232	0.09	0.03	blup	160	0.04	3.3e-05	10.19	9.6	9.8e-22	0.06	0.98	0.00	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	TSLP	0.06	0.07	blup	39	0.06	6.4e-07	-14.50	14.0	1.4e-44	-0.88	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	TSLP	0.02	0.02	blup	39	0.02	1.9e-03	-15.25	13.8	1.8e-43	-0.88	0.00	0.89	FALSE
38	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TSLP	0.04	0.03	enet	6	0.02	1.6e-03	-14.83	13.5	2.5e-41	-0.86	0.01	0.90	TRUE
39	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TMEM232	0.17	0.03	blup	162	0.06	1.9e-03	8.83	9.2	5.2e-20	0.09	0.12	0.19	FALSE
40	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TMEM232	0.07	0.03	blup	159	0.03	2.3e-02	4.14	7.2	5.7e-13	0.08	0.08	0.04	TRUE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM232	0.06	0.06	blup	161	0.08	3.7e-09	8.76	7.1	1.1e-12	0.11	1.00	0.00	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	TSLP	0.03	0.01	blup	39	0.02	2.7e-03	-9.86	10.9	1.1e-27	-0.69	0.04	0.53	FALSE
43	The Cancer Genome Atlas	Stomach Adenocarcinoma	WDR36	0.04	0.04	lasso	1	0.03	3.7e-03	-7.96	-8.0	1.7e-15	0.45	0.17	0.11	FALSE
44	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TSLP	0.12	0.11	lasso	3	0.08	6.9e-04	-15.28	15.2	3.2e-52	-0.92	0.00	0.97	TRUE
45	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM232	0.20	0.16	enet	17	0.24	2.3e-23	8.68	8.0	8.6e-16	0.10	1.00	0.00	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	TSLP	0.13	0.14	blup	39	0.15	1.4e-14	-14.50	11.6	6.3e-31	-0.75	0.01	0.99	TRUE
47	The Cancer Genome Atlas	Thyroid Carcinoma	WDR36	0.08	0.02	blup	73	0.05	1.5e-05	5.22	-7.3	2.6e-13	0.44	0.29	0.31	FALSE