[Hub]/) : Traits : Allergy or Eczema :

chr5:130,904,163-132,839,137

Best TWAS P=1.93e-10 · Best GWAS P=9.19e-14 conditioned to 2.07e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous KIF3A 0.08 0.07 lasso 3 0.07 1.2e-06 5.8 -6.0 2.0e-09 -0.30 0.95 0.01 FALSE
2 GTEx Artery Aorta KIF3A 0.13 0.07 enet 7 0.07 6.3e-05 5.6 -6.2 7.3e-10 -0.36 0.92 0.02 FALSE
3 GTEx Artery Tibial KIF3A 0.11 0.08 lasso 5 0.09 3.2e-07 5.6 -6.4 1.9e-10 -0.33 0.98 0.00 TRUE
4 GTEx Cells EBV-transformed lymphocytes SLC22A5 0.37 0.05 lasso 13 0.10 2.8e-04 -4.9 5.1 3.0e-07 0.29 0.49 0.03 FALSE
5 GTEx Cells Transformed fibroblasts KIF3A 0.15 0.16 enet 7 0.15 2.6e-11 5.6 -6.0 2.0e-09 -0.35 1.00 0.00 FALSE
6 GTEx Cells Transformed fibroblasts SEPT8 0.15 0.12 lasso 4 0.11 6.9e-09 5.6 -5.9 3.8e-09 -0.29 0.99 0.00 FALSE
7 GTEx Esophagus Muscularis KIF3A 0.31 0.17 lasso 5 0.20 2.2e-12 5.5 -5.9 3.8e-09 -0.34 1.00 0.00 FALSE
8 GTEx Nerve Tibial KIF3A 0.23 0.17 lasso 5 0.15 5.3e-11 5.8 -6.0 2.4e-09 -0.38 1.00 0.00 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic SEPT8 0.15 0.17 lasso 2 0.17 1.4e-09 5.8 6.1 8.1e-10 0.37 0.98 0.00 FALSE
10 GTEx Skin Sun Exposed Lower leg KIF3A 0.11 0.04 lasso 4 0.04 6.2e-04 5.8 -6.2 5.3e-10 -0.32 0.63 0.03 FALSE
11 GTEx Skin Sun Exposed Lower leg SEPT8 0.46 0.35 lasso 6 0.33 3.2e-28 5.6 5.8 4.8e-09 0.25 1.00 0.00 FALSE
12 GTEx Thyroid PDLIM4 0.05 0.02 enet 5 0.01 3.1e-02 -3.5 5.3 1.3e-07 0.47 0.16 0.65 FALSE
13 METSIM Adipose KIF3A 0.08 0.08 lasso 15 0.07 4.0e-11 4.8 -5.4 5.3e-08 -0.31 1.00 0.00 FALSE
14 NTR Blood IRF1 0.03 0.02 blup 424 0.01 5.7e-05 4.6 -5.6 1.9e-08 -0.12 1.00 0.00 TRUE