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chr5:176,040,488-177,426,530

Best TWAS P=6.97e-12 · Best GWAS P=1.24e-10 conditioned to 0.297

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RGS14	0.29	0.16	lasso	7	0.20	2.2e-23	5.1	-6.1	1.2e-09	-0.80	0.53	0.47	FALSE
2	GTEx	Adipose Subcutaneous	RGS14	0.31	0.10	lasso	3	0.10	2.8e-08	5.3	-5.4	6.6e-08	-0.64	0.68	0.32	FALSE
3	GTEx	Adrenal Gland	RGS14	0.28	0.24	lasso	4	0.24	3.7e-09	5.3	-5.5	3.7e-08	-0.64	0.64	0.36	FALSE
4	GTEx	Artery Aorta	RGS14	0.35	0.31	lasso	6	0.29	1.5e-16	5.1	-5.3	9.0e-08	-0.73	0.78	0.22	FALSE
5	GTEx	Artery Aorta	LMAN2	0.13	0.10	lasso	6	0.06	1.9e-04	6.4	6.3	2.6e-10	0.98	0.01	0.98	FALSE
6	GTEx	Artery Tibial	RGS14	0.49	0.12	enet	10	0.14	6.2e-11	5.1	-6.0	2.0e-09	-0.74	0.45	0.55	FALSE
7	GTEx	Breast Mammary Tissue	RGS14	0.13	0.14	lasso	1	0.11	2.0e-06	5.1	-5.1	2.7e-07	-0.71	0.55	0.30	FALSE
8	GTEx	Cells Transformed fibroblasts	RGS14	0.52	0.39	lasso	6	0.47	4.9e-39	5.1	-5.7	1.3e-08	-0.70	0.89	0.11	FALSE
9	GTEx	Esophagus Mucosa	RGS14	0.31	0.23	enet	8	0.24	5.2e-16	5.3	-5.5	2.8e-08	-0.63	0.70	0.30	FALSE
10	GTEx	Esophagus Muscularis	RGS14	0.13	0.12	enet	3	0.15	3.7e-09	5.1	-6.0	1.9e-09	-0.73	0.04	0.96	FALSE
11	GTEx	Heart Atrial Appendage	RGS14	0.18	0.18	lasso	2	0.20	2.5e-09	5.1	-5.4	7.2e-08	-0.70	0.53	0.46	FALSE
12	GTEx	Lung	RGS14	0.12	0.11	lasso	1	0.08	5.5e-07	5.1	-5.1	2.7e-07	-0.71	0.58	0.41	FALSE
13	GTEx	Nerve Tibial	RGS14	0.22	0.10	lasso	6	0.08	1.8e-06	5.3	-5.5	3.6e-08	-0.67	0.47	0.49	FALSE
14	GTEx	Pancreas	RGS14	0.25	0.12	lasso	13	0.12	1.5e-05	6.4	-5.8	4.8e-09	-0.93	0.01	0.99	FALSE
15	GTEx	Pituitary	RGS14	0.48	0.34	lasso	6	0.35	1.4e-09	5.1	-5.3	1.4e-07	-0.70	0.24	0.74	FALSE
16	GTEx	Skin Sun Exposed Lower leg	RGS14	0.15	0.16	lasso	3	0.15	9.1e-13	5.1	-5.3	1.2e-07	-0.71	0.84	0.16	FALSE
17	GTEx	Stomach	RGS14	0.11	0.17	enet	6	0.17	1.1e-08	5.3	-5.4	6.8e-08	-0.69	0.40	0.57	FALSE
18	GTEx	Testis	RGS14	0.63	0.47	enet	9	0.47	4.8e-23	5.1	-5.9	2.9e-09	-0.73	0.32	0.68	FALSE
19	GTEx	Thyroid	RGS14	0.15	0.14	enet	9	0.13	2.2e-10	5.3	-5.7	9.9e-09	-0.68	0.25	0.75	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	RGS14	0.32	0.35	enet	12	0.38	1.1e-51	6.0	-6.1	1.2e-09	-0.74	0.03	0.97	FALSE
21	YFS	Blood	MXD3	0.04	0.03	lasso	4	0.04	5.8e-13	6.3	-5.3	1.4e-07	-0.80	0.01	0.99	FALSE
22	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RGS14	0.09	0.08	enet	7	0.10	1.2e-08	5.1	-5.8	5.9e-09	-0.79	0.16	0.84	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	RGS14	0.08	0.10	lasso	2	0.12	1.5e-23	6.3	-6.1	9.7e-10	-0.74	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	RAB24	0.08	0.04	enet	7	0.06	3.4e-04	6.2	-5.3	8.8e-08	-0.81	0.01	0.79	FALSE
25	The Cancer Genome Atlas	Glioblastoma Multiforme	RGS14	0.22	0.24	blup	39	0.27	6.9e-09	5.9	-6.9	7.0e-12	-0.86	0.03	0.97	TRUE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RGS14	0.10	0.07	lasso	2	0.09	3.9e-10	5.9	-5.9	4.2e-09	-0.73	0.06	0.94	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	RGS14	0.03	0.02	blup	39	0.03	8.1e-05	6.0	-6.4	1.3e-10	-0.91	0.02	0.98	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RGS14	0.14	0.12	lasso	3	0.13	2.1e-14	5.3	-5.5	4.8e-08	-0.63	0.82	0.18	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RGS14	0.13	0.13	lasso	2	0.14	1.1e-09	5.1	-5.4	5.4e-08	-0.68	0.68	0.32	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RGS14	0.07	0.11	lasso	3	0.10	8.2e-05	5.5	-5.8	5.4e-09	-0.75	0.04	0.84	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	RGS14	0.30	0.18	blup	39	0.25	1.6e-25	5.3	-5.7	1.3e-08	-0.63	0.56	0.44	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	RGS14	0.03	0.03	lasso	2	0.04	1.3e-03	5.1	-5.3	1.5e-07	-0.71	0.04	0.53	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	RGS14	0.26	0.18	lasso	5	0.19	4.5e-18	6.3	-6.3	2.1e-10	-0.73	0.02	0.98	FALSE