[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr17:37,137,299-39,048,774

Best TWAS P=7.38e-09 · Best GWAS P=2.43e-09 conditioned to 0.045

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Heart Atrial Appendage	PNMT	0.14	-0.01	lasso	8	0.00	5.3e-01	5.4	-5.8	7.4e-09	-0.85	0.06	0.70	TRUE
1	GTEx	Brain Nucleus accumbens basal ganglia	RAPGEFL1	0.16	0.06	lasso	4	0.07	7.7e-03	5.4	5.6	2.5e-08	0.87	0.04	0.72	FALSE
5	NTR	Blood	IKZF3	0.04	0.03	blup	319	0.02	1.5e-08	5.5	5.5	4.3e-08	0.89	0.02	0.98	FALSE
7	YFS	Blood	ORMDL3	0.31	0.36	lasso	9	0.45	2.2e-165	-5.6	-5.3	1.2e-07	-0.88	0.05	0.95	FALSE
10	The Cancer Genome Atlas	Rectum Adenocarcinoma	GSDMB	0.14	0.09	blup	39	0.17	7.0e-05	5.0	-5.3	1.2e-07	-0.93	0.02	0.90	FALSE
4	GTEx	Whole Blood	GSDMB	0.15	0.10	lasso	4	0.10	4.5e-09	-5.3	-5.3	1.4e-07	-0.94	0.09	0.91	FALSE
2	GTEx	Heart Atrial Appendage	ERBB2	0.13	0.04	enet	18	0.02	4.8e-02	-3.7	-5.2	1.7e-07	-0.66	0.10	0.66	FALSE
6	YFS	Blood	GSDMB	0.36	0.41	lasso	12	0.49	4.0e-186	-5.6	-5.2	2.0e-07	-0.91	0.05	0.95	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	GSDMB	0.10	0.15	blup	40	0.14	1.2e-08	6.0	-5.2	2.2e-07	-0.95	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	GSDMB	0.14	0.16	lasso	4	0.14	2.4e-06	5.9	-5.2	2.4e-07	-0.99	0.01	0.99	FALSE