[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr17:37,137,299-39,048,774

Best TWAS P=7.38e-09 · Best GWAS P=2.43e-09 conditioned to 0.045

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Nucleus accumbens basal ganglia RAPGEFL1 0.16 0.06 lasso 4 0.07 7.7e-03 5.4 5.6 2.5e-08 0.87 0.04 0.72 FALSE
2 GTEx Heart Atrial Appendage ERBB2 0.13 0.04 enet 18 0.02 4.8e-02 -3.7 -5.2 1.7e-07 -0.66 0.10 0.66 FALSE
3 GTEx Heart Atrial Appendage PNMT 0.14 -0.01 lasso 8 0.00 5.3e-01 5.4 -5.8 7.4e-09 -0.85 0.06 0.70 TRUE
4 GTEx Whole Blood GSDMB 0.15 0.10 lasso 4 0.10 4.5e-09 -5.3 -5.3 1.4e-07 -0.94 0.09 0.91 FALSE
5 NTR Blood IKZF3 0.04 0.03 blup 319 0.02 1.5e-08 5.5 5.5 4.3e-08 0.89 0.02 0.98 FALSE
6 YFS Blood GSDMB 0.36 0.41 lasso 12 0.49 4.0e-186 -5.6 -5.2 2.0e-07 -0.91 0.05 0.95 FALSE
7 YFS Blood ORMDL3 0.31 0.36 lasso 9 0.45 2.2e-165 -5.6 -5.3 1.2e-07 -0.88 0.05 0.95 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma GSDMB 0.10 0.15 blup 40 0.14 1.2e-08 6.0 -5.2 2.2e-07 -0.95 0.01 0.99 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma GSDMB 0.14 0.16 lasso 4 0.14 2.4e-06 5.9 -5.2 2.4e-07 -0.99 0.01 0.99 FALSE
10 The Cancer Genome Atlas Rectum Adenocarcinoma GSDMB 0.14 0.09 blup 39 0.17 7.0e-05 5.0 -5.3 1.2e-07 -0.93 0.02 0.90 FALSE