TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2012)
:
←
→
chr19:9,829,303-11,275,258
Best TWAS P=2.49e-09 · Best GWAS P=1.66e-08 conditioned to 4.11e-05
9.8M
10M
10.2M
10.4M
10.6M
10.8M
11M
11.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Testis
PDE4A
0.20
0.02
enet
39
0.04
0.00642
5.1
6.0
2.5e-09
-0.11
0.03
0.41
TRUE
2
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
S1PR5
0.05
0.04
lasso
4
0.04
0.00052
3.7
-5.2
1.8e-07
0.32
0.03
0.38
TRUE