[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr2:233,227,833-234,904,144

Best TWAS P=1.75e-37 · Best GWAS P=3.88e-38 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATG16L1	0.06	0.03	bslmm	587	0.03	3.3e-04	-4.9	8.5	2.6e-17	-0.61	0.06	0.90	FALSE
2	GTEx	Adipose Subcutaneous	ATG16L1	0.14	0.11	lasso	4	0.10	6.4e-09	-12.1	-12.2	4.3e-34	0.96	0.02	0.98	FALSE
3	GTEx	Brain Caudate basal ganglia	ATG16L1	0.21	0.09	lasso	2	0.10	6.8e-04	-9.2	-8.8	8.9e-19	0.75	0.10	0.57	FALSE
4	GTEx	Brain Cerebellum	ATG16L1	0.23	0.27	lasso	4	0.30	2.0e-09	-12.8	-12.8	1.8e-37	0.98	0.02	0.98	TRUE
5	GTEx	Esophagus Mucosa	ATG16L1	0.11	0.02	enet	10	0.00	2.3e-01	-12.9	12.2	2.6e-34	-0.88	0.02	0.91	FALSE
6	GTEx	Esophagus Muscularis	ATG16L1	0.11	0.03	lasso	6	0.02	2.7e-02	-10.5	-11.9	1.3e-32	0.95	0.02	0.97	FALSE
7	GTEx	Nerve Tibial	ATG16L1	0.24	0.18	enet	21	0.19	3.5e-13	-12.1	-10.6	3.8e-26	0.90	0.03	0.97	FALSE
8	GTEx	Pituitary	ATG16L1	0.36	0.16	lasso	8	0.19	1.3e-05	-7.9	-7.0	2.1e-12	0.71	0.06	0.87	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	ATG16L1	0.12	0.10	enet	11	0.11	1.7e-06	-12.8	12.5	7.6e-36	-0.98	0.02	0.98	FALSE
10	GTEx	Skin Sun Exposed Lower leg	ATG16L1	0.21	0.08	enet	18	0.10	5.6e-09	-12.8	10.8	2.7e-27	-0.90	0.02	0.98	FALSE
11	GTEx	Testis	ATG16L1	0.34	0.19	enet	29	0.23	1.4e-10	-12.8	11.2	2.5e-29	-0.86	0.02	0.98	FALSE
12	METSIM	Adipose	INPP5D	0.05	0.01	lasso	4	0.03	6.2e-06	1.6	-8.1	6.7e-16	0.56	0.02	0.97	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	ATG16L1	0.28	0.26	lasso	9	0.28	3.3e-36	-5.7	-8.4	4.9e-17	0.78	1.00	0.00	FALSE
14	YFS	Blood	ATG16L1	0.21	0.28	lasso	7	0.30	2.2e-99	-5.7	7.5	7.5e-14	-0.72	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SCARNA5	0.03	0.01	blup	55	0.02	2.4e-03	-7.4	6.6	3.3e-11	-0.62	0.07	0.17	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATG16L1	0.22	0.06	enet	36	0.10	6.2e-12	-12.1	-10.0	1.5e-23	0.69	0.03	0.97	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ATG16L1	0.11	0.05	blup	81	0.09	1.9e-04	-12.1	-11.4	6.8e-30	0.91	0.02	0.85	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	ATG16L1	0.07	0.04	lasso	4	0.03	3.6e-03	-7.8	7.7	1.2e-14	-0.72	0.03	0.18	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	SCARNA5	0.04	0.00	blup	55	0.02	8.2e-03	-10.5	-10.0	2.1e-23	0.74	0.02	0.50	FALSE