[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr2:101,981,794-103,767,612

Best TWAS P=4.46e-10 · Best GWAS P=1.48e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IL18R1 0.31 0.38 bslmm 580 0.38 5.4e-49 -5.1 5.2 1.7e-07 0.61 0.86 0.14 FALSE
2 GTEx Brain Caudate basal ganglia IL18R1 0.17 0.23 lasso 6 0.20 1.6e-06 -5.1 5.1 2.9e-07 0.53 0.59 0.28 FALSE
3 GTEx Brain Cortex IL18R1 0.21 0.12 lasso 9 0.13 1.7e-04 -5.1 5.2 2.3e-07 0.59 0.31 0.37 FALSE
4 GTEx Brain Hippocampus IL18R1 0.25 0.06 lasso 11 0.07 1.0e-02 3.4 5.6 1.7e-08 0.82 0.05 0.81 FALSE
5 GTEx Brain Putamen basal ganglia IL18R1 0.30 0.22 enet 21 0.24 1.8e-06 -5.1 5.1 2.8e-07 0.49 0.38 0.36 FALSE
6 GTEx Heart Atrial Appendage IL1R1 0.13 0.04 enet 26 0.06 9.8e-04 4.4 5.9 3.1e-09 0.68 0.04 0.80 FALSE
7 GTEx Skin Sun Exposed Lower leg IL18R1 0.05 0.02 lasso 6 0.02 7.4e-03 5.9 6.1 1.1e-09 0.98 0.02 0.96 FALSE
8 GTEx Whole Blood IL18RAP 0.14 0.18 lasso 10 0.18 6.0e-16 5.5 -5.5 4.7e-08 -0.97 0.03 0.97 FALSE
9 NTR Blood IL1RL1 0.04 0.04 lasso 6 0.04 7.7e-13 6.3 -6.2 4.5e-10 -0.99 0.01 0.99 TRUE
10 ROSMAP Brain Pre-frontal Cortex IL18R1 0.42 0.52 lasso 5 0.52 6.2e-78 -5.1 5.2 2.4e-07 0.53 0.80 0.20 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma IL18RAP 0.03 0.03 lasso 3 0.01 7.7e-03 5.9 -5.4 5.7e-08 -0.95 0.01 0.94 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma IL1RL1 0.13 0.20 enet 8 0.20 4.5e-22 -5.2 5.2 2.0e-07 0.53 0.02 0.98 FALSE