[Hub]/) : Traits : Blood Eosinophil Count :

chr10:5,027,660-7,317,647

Best TWAS P=4.16e-11 · Best GWAS P=3.51e-21 conditioned to 4.05e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial FBXO18 0.13 0.01 enet 25 0.02 9.1e-03 1.9 -5.4 6.0e-08 -0.12 0.18 0.04 TRUE
2 GTEx Heart Atrial Appendage FAM208B 0.23 0.02 lasso 12 0.06 1.2e-03 -5.5 -5.5 3.0e-08 0.00 0.11 0.35 TRUE
3 GTEx Nerve Tibial FBXO18 0.10 0.00 lasso 5 0.00 5.5e-01 -6.3 -6.1 8.5e-10 -0.24 0.17 0.05 FALSE
4 GTEx Skin Sun Exposed Lower leg FAM208B 0.10 0.03 lasso 4 0.03 1.4e-03 -4.3 -6.6 4.2e-11 -0.70 0.01 0.93 TRUE
5 METSIM Adipose IL2RA 0.07 0.02 lasso 3 0.02 1.0e-03 5.5 6.1 9.5e-10 0.43 0.44 0.20 TRUE
6 YFS Blood PRKCQ 0.04 0.03 lasso 3 0.02 9.7e-09 5.8 -5.5 3.5e-08 -0.01 1.00 0.00 TRUE