Best TWAS P=4.16e-11 · Best GWAS P=3.51e-21 conditioned to 4.05e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | FBXO18 | 0.13 | 0.01 | enet | 25 | 0.02 | 9.1e-03 | 1.9 | -5.4 | 6.0e-08 | -0.12 | 0.18 | 0.04 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | FAM208B | 0.23 | 0.02 | lasso | 12 | 0.06 | 1.2e-03 | -5.5 | -5.5 | 3.0e-08 | 0.00 | 0.11 | 0.35 | TRUE |
| 3 | GTEx | Nerve Tibial | FBXO18 | 0.10 | 0.00 | lasso | 5 | 0.00 | 5.5e-01 | -6.3 | -6.1 | 8.5e-10 | -0.24 | 0.17 | 0.05 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | FAM208B | 0.10 | 0.03 | lasso | 4 | 0.03 | 1.4e-03 | -4.3 | -6.6 | 4.2e-11 | -0.70 | 0.01 | 0.93 | TRUE |
| 5 | METSIM | Adipose | IL2RA | 0.07 | 0.02 | lasso | 3 | 0.02 | 1.0e-03 | 5.5 | 6.1 | 9.5e-10 | 0.43 | 0.44 | 0.20 | TRUE |
| 6 | YFS | Blood | PRKCQ | 0.04 | 0.03 | lasso | 3 | 0.02 | 9.7e-09 | 5.8 | -5.5 | 3.5e-08 | -0.01 | 1.00 | 0.00 | TRUE |