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chr10:98,284,805-99,903,704

Best TWAS P=5.75e-11 · Best GWAS P=4.68e-10 conditioned to 0.0655

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ARHGAP19	0.07	0.05	lasso	5	0.04	3.2e-06	-5.5	5.3	1.3e-07	-0.90	0.22	0.74	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FRAT2	0.05	0.04	lasso	2	0.04	2.3e-05	-5.1	5.9	3.0e-09	-0.89	0.03	0.97	FALSE
3	GTEx	Artery Tibial	ARHGAP19	0.09	0.06	lasso	4	0.05	9.3e-05	-5.5	5.2	1.5e-07	-0.90	0.05	0.94	FALSE
4	GTEx	Cells Transformed fibroblasts	FRAT1	0.08	0.04	lasso	3	0.05	2.3e-04	-6.1	6.2	6.4e-10	-0.98	0.01	0.97	FALSE
5	GTEx	Esophagus Mucosa	FRAT2	0.09	0.07	lasso	5	0.09	1.4e-06	4.2	5.4	7.9e-08	-0.54	0.85	0.12	FALSE
6	GTEx	Lung	ARHGAP19	0.14	0.05	lasso	5	0.03	3.6e-03	-6.1	5.4	8.2e-08	-0.94	0.02	0.98	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ARHGAP19	0.14	0.06	lasso	4	0.05	8.9e-04	-6.1	6.0	1.5e-09	-0.97	0.02	0.98	FALSE
8	GTEx	Skin Sun Exposed Lower leg	ARHGAP19	0.16	0.11	lasso	7	0.12	3.4e-10	-5.5	5.3	1.2e-07	-0.90	0.03	0.97	FALSE
9	GTEx	Testis	FRAT2	0.19	0.10	lasso	3	0.13	1.7e-06	-4.9	5.6	1.8e-08	-0.88	0.08	0.91	FALSE
10	GTEx	Whole Blood	FRAT2	0.06	0.01	enet	7	0.01	8.8e-02	-5.2	5.8	9.2e-09	-0.68	0.16	0.60	FALSE
11	METSIM	Adipose	FRAT1	0.06	0.03	lasso	10	0.03	2.2e-05	4.4	5.3	1.5e-07	-0.48	0.82	0.18	FALSE
12	NTR	Blood	FRAT1	0.05	0.03	lasso	3	0.05	3.2e-16	4.2	5.5	3.7e-08	-0.56	1.00	0.00	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	EXOSC1	0.04	0.01	enet	12	0.01	6.7e-03	-6.2	5.2	1.6e-07	-0.86	0.01	0.98	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	FRAT2	0.06	0.07	lasso	4	0.07	3.0e-09	-5.4	6.0	2.5e-09	-0.86	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RRP12	0.13	-0.01	blup	58	0.03	1.7e-02	4.4	5.8	6.1e-09	-0.67	0.04	0.36	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARHGAP19	0.04	0.03	lasso	3	0.02	6.5e-03	-5.1	5.4	6.8e-08	-0.72	0.07	0.66	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	FRAT2	0.02	0.00	blup	39	0.01	3.2e-02	-5.1	6.5	5.8e-11	-0.77	0.01	0.49	TRUE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RRP12	0.09	0.05	blup	57	0.05	1.6e-03	4.2	5.4	6.8e-08	-0.46	0.22	0.10	FALSE
19	The Cancer Genome Atlas	Rectum Adenocarcinoma	RRP12	0.32	0.07	blup	56	0.11	1.9e-03	4.4	5.9	3.5e-09	-0.71	0.02	0.28	FALSE