[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr13:39,533,590-43,594,717

Best TWAS P=4.29e-44 · Best GWAS P=4.34e-54 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	COG6	0.14	0.06	enet	35	0.07	2.6e-09	3.5	-5.2	2.6e-07	0.01	0.89	0.02	TRUE
2	GTEx	Adipose Subcutaneous	COG6	0.20	0.16	lasso	4	0.14	3.1e-11	-7.9	8.2	2.6e-16	-0.04	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	CYCSP34	0.08	0.03	lasso	7	0.02	1.0e-02	-8.6	8.4	6.5e-17	0.12	0.26	0.08	FALSE
4	GTEx	Adipose Visceral Omentum	COG6	0.13	0.12	enet	13	0.13	2.9e-07	-8.1	7.4	1.8e-13	-0.02	0.90	0.05	FALSE
5	GTEx	Artery Aorta	COG6	0.31	0.23	enet	15	0.28	9.4e-16	-8.1	7.0	2.1e-12	-0.02	1.00	0.00	TRUE
6	GTEx	Artery Tibial	COG6	0.15	0.11	lasso	4	0.12	8.1e-10	-8.2	8.6	1.0e-17	-0.04	0.93	0.07	FALSE
7	GTEx	Artery Tibial	CYCSP34	0.09	0.02	lasso	7	0.04	4.6e-04	-9.3	8.5	1.8e-17	0.05	0.76	0.01	FALSE
8	GTEx	Brain Caudate basal ganglia	CYCSP34	0.21	0.11	lasso	2	0.13	1.2e-04	-9.9	10.0	1.9e-23	0.26	0.31	0.10	FALSE
9	GTEx	Brain Cerebellar Hemisphere	TPTE2P5	0.39	0.27	lasso	4	0.19	1.6e-05	-9.5	9.3	1.1e-20	0.18	0.70	0.02	FALSE
10	GTEx	Brain Cerebellar Hemisphere	CYCSP34	0.37	0.29	lasso	6	0.25	4.8e-07	-9.5	9.4	6.4e-21	0.18	0.89	0.01	FALSE
11	GTEx	Brain Cerebellum	CYCSP34	0.39	0.27	lasso	9	0.29	3.1e-09	-9.5	10.7	1.3e-26	0.24	0.97	0.00	FALSE
12	GTEx	Brain Cortex	CYCSP34	0.35	0.06	enet	34	0.10	1.1e-03	-9.5	7.4	9.7e-14	0.12	0.15	0.04	FALSE
13	GTEx	Brain Frontal Cortex BA9	TPTE2P5	0.22	-0.01	lasso	3	-0.01	5.4e-01	-10.1	10.7	6.0e-27	0.22	0.04	0.31	FALSE
14	GTEx	Brain Hippocampus	COG6	0.29	0.18	lasso	2	0.11	1.5e-03	-8.1	7.8	7.3e-15	-0.03	0.14	0.55	FALSE
15	GTEx	Brain Hippocampus	CYCSP34	0.16	0.25	lasso	2	0.22	6.1e-06	-8.6	8.7	4.3e-18	0.16	0.40	0.04	FALSE
16	GTEx	Brain Nucleus accumbens basal ganglia	CYCSP34	0.20	0.03	lasso	6	0.11	5.6e-04	-9.9	5.3	9.8e-08	0.11	0.13	0.05	FALSE
17	GTEx	Brain Putamen basal ganglia	CYCSP34	0.40	0.04	enet	17	0.22	6.9e-06	-9.5	7.7	1.8e-14	0.17	0.14	0.05	FALSE
18	GTEx	Cells Transformed fibroblasts	COG6	0.44	0.41	lasso	3	0.40	1.2e-31	-7.9	8.0	1.7e-15	-0.04	1.00	0.00	FALSE
19	GTEx	Esophagus Mucosa	CYCSP34	0.10	0.02	enet	30	0.03	5.8e-03	-2.5	-5.5	4.2e-08	-0.47	0.17	0.54	FALSE
20	GTEx	Esophagus Muscularis	COG6	0.21	0.19	lasso	3	0.19	1.6e-11	-8.1	8.2	2.5e-16	-0.03	1.00	0.00	FALSE
21	GTEx	Heart Atrial Appendage	COG6	0.15	0.06	lasso	5	0.02	2.8e-02	-8.1	7.9	2.2e-15	-0.02	0.40	0.16	FALSE
22	GTEx	Heart Left Ventricle	COG6	0.22	0.16	lasso	6	0.15	3.4e-08	-8.0	9.3	1.2e-20	-0.02	0.16	0.84	TRUE
23	GTEx	Lung	COG6	0.10	0.04	enet	13	0.06	2.5e-05	-7.9	7.9	2.7e-15	-0.04	0.77	0.15	FALSE
24	GTEx	Muscle Skeletal	COG6	0.41	0.40	enet	25	0.45	8.6e-49	-7.9	8.6	7.5e-18	-0.04	1.00	0.00	FALSE
25	GTEx	Nerve Tibial	COG6	0.20	0.18	lasso	3	0.18	1.0e-12	-7.9	8.0	9.4e-16	-0.04	1.00	0.00	FALSE
26	GTEx	Nerve Tibial	CYCSP34	0.05	0.01	lasso	4	0.02	2.8e-02	-9.5	10.5	9.4e-26	0.18	0.29	0.05	FALSE
27	GTEx	Pituitary	TPTE2P5	0.28	0.10	lasso	13	0.10	1.8e-03	-9.6	9.6	6.0e-22	0.17	0.23	0.05	FALSE
28	GTEx	Small Intestine Terminal Ileum	CYCSP34	0.25	0.07	lasso	3	0.05	3.0e-02	-9.2	7.8	8.6e-15	0.00	0.09	0.06	FALSE
29	GTEx	Spleen	CYCSP34	0.32	0.07	lasso	4	0.06	1.2e-02	-11.1	11.2	6.2e-29	0.28	0.08	0.19	TRUE
30	GTEx	Testis	AKAP11	0.15	0.03	enet	13	0.09	6.4e-05	-0.4	-5.5	3.0e-08	0.03	0.14	0.57	TRUE
31	GTEx	Testis	COG6	0.43	0.37	enet	37	0.37	2.2e-17	6.1	8.2	2.8e-16	-0.06	1.00	0.00	FALSE
32	GTEx	Testis	CYCSP34	0.09	0.05	lasso	3	0.05	2.0e-03	-9.6	5.7	1.2e-08	-0.06	0.33	0.03	TRUE
33	GTEx	Thyroid	TPTE2P5	0.17	0.00	enet	36	0.01	3.4e-02	13.9	-6.7	1.6e-11	-0.41	0.11	0.14	FALSE
34	GTEx	Whole Blood	COG6	0.10	0.07	lasso	4	0.08	7.0e-08	-7.9	8.5	1.8e-17	-0.04	0.78	0.19	FALSE
35	METSIM	Adipose	COG6	0.07	0.06	enet	8	0.06	8.1e-10	-7.9	8.7	4.4e-18	-0.03	0.76	0.24	FALSE
36	METSIM	Adipose	ELF1	0.04	0.02	bslmm	386	0.02	1.1e-03	1.1	6.3	2.3e-10	0.32	0.16	0.03	FALSE
37	YFS	Blood	FOXO1	0.02	0.02	lasso	4	0.02	3.3e-08	-3.3	10.4	3.0e-25	0.38	0.65	0.22	TRUE
38	YFS	Blood	MRPS31	0.05	0.02	blup	387	0.03	6.5e-11	12.6	-12.6	1.7e-36	-0.75	0.23	0.77	FALSE
39	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SUGT1L1	0.10	0.00	blup	58	0.04	3.9e-04	-9.9	11.9	1.7e-32	0.58	0.01	0.55	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	SUGT1L1	0.09	0.06	lasso	7	0.09	8.4e-18	-1.8	9.4	7.7e-21	0.67	0.01	0.99	FALSE
41	The Cancer Genome Atlas	Glioblastoma Multiforme	COG6	0.24	0.20	lasso	5	0.16	1.2e-05	-8.1	7.8	6.4e-15	-0.03	0.36	0.40	FALSE
42	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SUGT1L1	0.06	0.01	blup	58	0.03	1.9e-04	14.0	13.9	4.3e-44	0.68	0.00	0.98	TRUE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	COG6	0.04	0.03	blup	99	0.03	1.9e-04	5.8	7.9	2.5e-15	-0.01	0.56	0.20	FALSE
44	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SUGT1L1	0.29	0.23	lasso	8	0.25	1.7e-28	-1.8	7.6	2.7e-14	0.65	0.98	0.02	FALSE
45	The Cancer Genome Atlas	Brain Lower Grade Glioma	COG6	0.13	0.15	lasso	14	0.19	1.1e-20	-8.0	8.5	2.8e-17	-0.04	1.00	0.00	FALSE
46	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUGT1L1	0.32	0.22	blup	59	0.27	1.3e-30	-1.8	8.8	1.6e-18	0.62	1.00	0.00	TRUE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	SUGT1L1	0.12	0.02	blup	58	0.05	1.4e-06	12.6	12.1	8.0e-34	0.65	0.00	0.99	FALSE
48	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SUGT1L1	0.09	0.03	blup	58	0.07	2.4e-05	-1.7	6.5	5.9e-11	0.59	0.02	0.85	FALSE
49	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SUGT1L1	0.34	0.15	enet	17	0.17	9.3e-08	-1.9	7.2	8.9e-13	0.57	0.26	0.66	FALSE
50	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SUGT1L1	0.22	0.07	lasso	11	0.13	9.4e-06	14.0	9.4	4.2e-21	0.73	0.01	0.96	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	SUGT1L1	0.21	0.11	lasso	9	0.16	5.7e-16	-1.8	8.6	5.7e-18	0.69	0.02	0.98	FALSE
52	The Cancer Genome Atlas	Stomach Adenocarcinoma	SUGT1L1	0.09	0.06	blup	59	0.06	5.4e-05	14.0	10.9	9.4e-28	0.72	0.00	1.00	FALSE
53	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SUGT1L1	0.17	0.02	blup	58	0.05	1.0e-02	3.1	6.2	4.9e-10	0.52	0.02	0.15	TRUE
54	The Cancer Genome Atlas	Thyroid Carcinoma	AKAP11	0.07	0.09	lasso	3	0.08	3.7e-08	-5.3	5.3	1.1e-07	-0.05	0.02	0.98	TRUE