[Hub]/) : Traits : Blood Eosinophil Count :

chr14:54,715,845-56,575,157

Best TWAS P=1.31e-22 · Best GWAS P=3.61e-23 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATG14 0.03 0.02 blup 438 0.02 7.6e-04 9.9 9.5 1.7e-21 0.92 0.03 0.97 FALSE
2 CommonMind Brain Pre-frontal Cortex FBXO34 0.05 0.10 lasso 4 0.09 2.5e-11 9.8 -9.8 1.5e-22 -0.97 0.02 0.98 FALSE
3 CommonMind Brain Pre-frontal Cortex LGALS3 0.03 0.03 blup 421 0.02 1.2e-03 9.1 -8.0 1.1e-15 -0.87 0.06 0.92 FALSE
4 CommonMind Brain Pre-frontal Cortex MAPK1IP1L 0.05 0.00 blup 446 0.01 2.2e-02 3.2 5.9 3.2e-09 0.62 0.06 0.57 FALSE
5 CommonMind Brain Pre-frontal Cortex WDHD1 0.06 0.09 enet 24 0.09 5.7e-11 8.3 -8.1 4.5e-16 -0.75 0.87 0.13 FALSE
6 GTEx Adipose Subcutaneous ATG14 0.08 0.01 enet 30 0.06 2.1e-05 9.7 -8.0 9.3e-16 -0.80 0.04 0.96 FALSE
7 GTEx Adrenal Gland LGALS3 0.19 0.17 lasso 2 0.12 3.0e-05 9.0 -9.1 7.5e-20 -0.93 0.22 0.72 FALSE
8 GTEx Adrenal Gland WDHD1 0.18 0.12 lasso 2 0.09 3.9e-04 6.5 -6.4 1.1e-10 -0.69 0.20 0.14 FALSE
9 GTEx Artery Aorta LGALS3 0.12 0.03 enet 7 0.03 7.0e-03 9.6 -9.3 1.0e-20 -0.92 0.04 0.94 FALSE
10 GTEx Artery Tibial ATG14 0.05 0.06 enet 16 0.04 5.3e-04 9.7 -9.6 8.3e-22 -0.88 0.04 0.92 FALSE
11 GTEx Cells Transformed fibroblasts ATG14 0.10 0.01 lasso 8 0.02 7.3e-03 9.3 -9.4 7.2e-21 -0.92 0.06 0.94 FALSE
12 GTEx Cells Transformed fibroblasts MAPK1IP1L 0.05 0.05 lasso 1 0.02 8.7e-03 9.8 9.8 1.8e-22 0.98 0.04 0.91 FALSE
13 GTEx Esophagus Mucosa ATG14 0.13 0.13 lasso 9 0.17 1.2e-11 9.6 -9.3 1.7e-20 -0.95 0.04 0.96 FALSE
14 GTEx Esophagus Mucosa WDHD1 0.10 0.01 enet 16 0.03 3.4e-03 9.1 8.2 1.7e-16 0.78 0.06 0.74 FALSE
15 GTEx Muscle Skeletal ATG14 0.08 0.03 enet 27 0.03 6.5e-04 9.8 -7.1 1.5e-12 -0.75 0.03 0.96 FALSE
16 GTEx Nerve Tibial ATG14 0.06 0.02 lasso 6 0.00 4.7e-01 4.2 -5.6 1.7e-08 -0.66 0.06 0.64 FALSE
17 GTEx Nerve Tibial MAPK1IP1L 0.08 0.00 lasso 4 0.02 2.1e-02 9.0 8.5 2.6e-17 0.81 0.06 0.70 FALSE
18 GTEx Pituitary LGALS3 0.40 0.34 enet 20 0.43 3.5e-12 7.1 -8.3 7.1e-17 -0.89 0.24 0.76 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic ATG14 0.13 0.08 lasso 7 0.07 1.8e-04 9.7 -9.8 1.6e-22 -0.97 0.05 0.92 FALSE
20 GTEx Skin Sun Exposed Lower leg ATG14 0.10 0.10 lasso 3 0.15 1.0e-12 9.7 -8.6 5.2e-18 -0.89 0.03 0.97 FALSE
21 GTEx Skin Sun Exposed Lower leg FBXO34 0.05 0.00 enet 5 0.00 6.3e-01 9.7 -9.4 4.1e-21 -0.95 0.06 0.55 FALSE
22 GTEx Testis ATG14 0.12 0.16 lasso 4 0.15 3.4e-07 9.8 -9.7 4.9e-22 -0.97 0.03 0.97 FALSE
23 GTEx Thyroid FBXO34 0.12 0.09 lasso 6 0.10 4.3e-08 9.0 -8.2 2.6e-16 -0.89 0.75 0.25 FALSE
24 METSIM Adipose ATG14 0.05 0.06 lasso 3 0.07 4.5e-10 4.9 6.2 5.2e-10 0.66 0.75 0.25 FALSE
25 METSIM Adipose MAPK1IP1L 0.03 0.00 bslmm 436 0.01 4.2e-02 6.7 7.4 1.8e-13 0.68 0.32 0.34 FALSE
26 YFS Blood FBXO34 0.04 0.05 lasso 10 0.05 2.2e-15 6.7 8.3 9.0e-17 0.91 0.08 0.92 FALSE
27 YFS Blood LGALS3 0.02 0.04 enet 9 0.04 6.9e-13 9.0 -9.1 7.7e-20 -0.93 0.08 0.92 FALSE
28 The Cancer Genome Atlas Esophageal Carcinoma KIAA0831 0.10 0.05 blup 66 0.04 1.9e-02 9.7 -9.2 3.1e-20 -0.94 0.01 0.83 FALSE
29 The Cancer Genome Atlas Glioblastoma Multiforme KIAA0831 0.25 0.01 blup 62 0.12 2.3e-04 3.8 -7.4 1.3e-13 -0.64 0.02 0.44 FALSE
30 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA0831 0.03 0.03 blup 63 0.02 1.2e-03 9.5 -8.9 8.2e-19 -0.91 0.02 0.91 FALSE
31 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KIAA0831 0.02 0.04 lasso 1 0.04 2.2e-05 9.8 -9.8 1.3e-22 -0.96 0.01 0.95 TRUE
32 The Cancer Genome Atlas Brain Lower Grade Glioma FBXO34 0.02 0.02 blup 95 0.02 2.4e-03 9.8 9.4 3.8e-21 0.94 0.02 0.92 FALSE
33 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIAA0831 0.03 0.02 enet 19 0.02 6.7e-04 9.7 -8.1 7.6e-16 -0.75 0.01 0.82 FALSE
34 The Cancer Genome Atlas Prostate Adenocarcinoma KIAA0831 0.03 0.04 lasso 1 0.03 2.1e-04 7.1 -7.1 1.6e-12 -0.82 0.06 0.78 FALSE