[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr17:17,017,584-18,914,778

Best TWAS P=7.99e-12 · Best GWAS P=3.83e-12 conditioned to 0.0745

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DRG2	0.09	0.07	bslmm	315	0.09	4.2e-11	5.1	5.8	6.3e-09	-0.52	0.99	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TOM1L2	0.19	0.24	bslmm	425	0.24	2.4e-29	5.4	-5.4	8.1e-08	0.63	0.98	0.02	FALSE
3	GTEx	Adipose Subcutaneous	TOM1L2	0.04	0.04	lasso	3	0.04	5.3e-04	5.2	-5.4	6.5e-08	0.63	0.67	0.20	FALSE
4	GTEx	Adipose Visceral Omentum	TOM1L2	0.15	0.13	lasso	4	0.11	3.6e-06	5.4	-5.6	2.3e-08	0.64	0.93	0.06	FALSE
5	GTEx	Adipose Visceral Omentum	TOP3A	0.08	0.00	enet	15	0.00	6.5e-01	1.2	-5.2	2.4e-07	0.37	0.06	0.23	FALSE
6	GTEx	Artery Aorta	AC122129.1	0.06	0.01	lasso	5	0.00	3.6e-01	5.4	-6.7	2.8e-11	0.84	0.06	0.79	FALSE
7	GTEx	Artery Tibial	TOM1L2	0.06	0.02	enet	15	0.04	3.8e-04	5.9	-6.3	3.4e-10	0.71	0.12	0.86	FALSE
8	GTEx	Brain Cerebellum	TOM1L2	0.10	0.06	lasso	5	0.02	6.6e-02	5.6	-6.0	1.4e-09	0.68	0.15	0.37	FALSE
9	GTEx	Brain Putamen basal ganglia	LRRC48	0.14	0.01	lasso	18	0.02	1.3e-01	5.4	5.5	2.8e-08	-0.58	0.12	0.12	FALSE
10	GTEx	Cells Transformed fibroblasts	SREBF1	0.09	0.01	lasso	11	0.01	3.2e-02	5.7	5.9	4.7e-09	-0.63	0.20	0.09	FALSE
11	GTEx	Colon Transverse	DRG2	0.10	0.07	lasso	7	0.08	1.4e-04	4.8	-5.1	3.1e-07	0.57	0.88	0.09	FALSE
12	GTEx	Esophagus Muscularis	TOM1L2	0.06	0.07	enet	12	0.05	4.3e-04	5.7	-5.7	1.6e-08	0.64	0.69	0.24	FALSE
13	GTEx	Muscle Skeletal	TOM1L2	0.08	0.11	lasso	6	0.10	5.3e-10	5.2	-5.5	4.2e-08	0.65	0.98	0.02	FALSE
14	GTEx	Muscle Skeletal	AC122129.1	0.13	0.14	lasso	4	0.13	7.3e-13	5.2	-5.4	5.5e-08	0.63	0.95	0.05	FALSE
15	GTEx	Nerve Tibial	TOM1L2	0.11	0.04	enet	43	0.10	1.5e-07	5.7	-6.1	1.2e-09	0.54	0.52	0.47	FALSE
16	GTEx	Ovary	TOM1L2	0.28	0.01	lasso	7	0.04	3.1e-02	5.6	-6.3	3.9e-10	0.60	0.17	0.19	FALSE
17	GTEx	Pituitary	TOM1L2	0.43	0.20	enet	18	0.11	1.3e-03	-6.9	-6.8	8.0e-12	0.90	0.05	0.94	TRUE
18	GTEx	Thyroid	LRRC48	0.04	0.01	enet	16	0.01	2.7e-02	5.0	5.1	2.7e-07	-0.47	0.38	0.09	FALSE
19	GTEx	Whole Blood	SREBF1	0.04	0.06	lasso	5	0.05	2.4e-05	5.3	-5.2	2.0e-07	0.61	0.95	0.04	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	GID4	0.07	0.04	lasso	5	0.03	4.1e-05	5.1	5.1	3.1e-07	-0.51	0.97	0.02	FALSE
21	YFS	Blood	SREBF1	0.07	0.11	lasso	7	0.11	2.2e-33	5.2	-5.2	2.0e-07	0.65	0.99	0.01	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	TOM1L2	0.01	0.01	blup	83	0.01	1.8e-03	5.7	-5.7	1.3e-08	0.64	0.12	0.61	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LLGL1	0.08	0.02	blup	53	0.05	6.0e-06	2.9	5.1	2.8e-07	-0.27	0.00	0.13	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ATPAF2	0.13	0.00	blup	44	0.04	8.4e-03	5.4	5.5	3.8e-08	-0.48	0.02	0.77	FALSE
25	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LRRC48	0.07	0.05	enet	12	0.04	7.0e-03	5.6	5.8	6.5e-09	-0.62	0.03	0.71	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	SREBF1	0.04	0.03	blup	32	0.02	7.8e-03	5.0	5.7	1.1e-08	-0.64	0.01	0.84	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf39	0.05	0.05	blup	49	0.05	5.8e-06	5.4	5.5	4.6e-08	-0.57	0.02	0.97	FALSE