TWAS hub - DRG2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0880	0.0340	5.5e-09	0.072	0.089	0.083	0.090	0.074	3.8e-09	5.3e-11	2.9e-10	4.2e-11	2.2e-09
2	GTEx	Adipose Subcutaneous	0.0770	0.0450	7.0e-03	0.028	NA	0.017	NA	0.015	2.4e-03	NA	1.4e-02	NA	1.9e-02
3	GTEx	Artery Tibial	0.1343	0.0540	5.6e-04	-0.002	NA	0.006	NA	-0.003	4.7e-01	NA	1.1e-01	NA	6.3e-01
4	GTEx	Brain Cerebellar Hemisphere	0.3620	0.1420	9.6e-03	0.079	NA	0.096	NA	0.077	4.6e-03	NA	1.9e-03	NA	5.1e-03
5	GTEx	Brain Cerebellum	0.3570	0.1000	2.3e-04	0.205	NA	0.062	NA	0.169	1.1e-06	NA	6.8e-03	NA	1.1e-05
6	GTEx	Brain Cortex	0.3380	0.1180	1.0e-03	0.055	NA	0.084	NA	0.124	1.3e-02	NA	2.5e-03	NA	2.7e-04
7	GTEx	Breast Mammary Tissue	0.3290	0.0820	3.9e-07	0.126	NA	0.167	NA	0.123	5.3e-07	NA	6.1e-09	NA	7.0e-07
8	GTEx	Breast Mammary Tissue (Female)	0.0458	0.0464	1.2e-01	-0.002	NA	-0.010	NA	-0.010	3.8e-01	NA	9.7e-01	NA	9.9e-01
9	GTEx	Colon Transverse	0.1040	0.0450	1.3e-05	0.070	NA	0.064	NA	0.079	3.2e-04	NA	5.4e-04	NA	1.4e-04
10	GTEx	Esophagus Mucosa	0.0630	0.0380	8.3e-03	0.002	NA	0.005	NA	0.005	2.2e-01	NA	1.3e-01	NA	1.5e-01
11	GTEx	Esophagus Muscularis	0.1270	0.0650	8.3e-03	0.013	NA	0.006	NA	0.008	5.2e-02	NA	1.3e-01	NA	9.9e-02
12	GTEx	Lung	0.1777	0.0561	2.6e-05	0.104	NA	0.091	NA	0.090	2.5e-08	NA	1.9e-07	NA	2.0e-07
13	GTEx	Nerve Tibial	0.1452	0.0541	2.2e-04	0.063	NA	0.080	NA	0.098	2.8e-05	NA	2.6e-06	NA	1.9e-07
14	GTEx	Skin Sun Exposed Lower leg	0.0640	0.0320	2.0e-04	0.073	NA	0.072	NA	0.076	1.2e-06	NA	1.3e-06	NA	6.5e-07
15	GTEx	Thyroid	0.1600	0.0500	2.6e-06	0.079	NA	0.122	NA	0.132	1.3e-06	NA	1.3e-09	NA	2.9e-10
16	ROSMAP	Brain Pre-frontal Cortex	0.2333	0.0551	4.4e-10	0.091	0.078	0.068	0.093	0.082	1.0e-11	2.9e-10	3.7e-09	6.0e-12	1.1e-10
17	TCGA	Lung Adenocarcinoma	0.0856	0.0406	4.1e-03	0.017	0.027	0.014	NA	0.020	3.8e-03	3.8e-04	8.6e-03	NA	2.0e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Waist Hip Ratio (WHR)	9.0	40.5	92.0	4.5	-5.4	-4.8	-1.9	-4.7	-4.6	-8.2	-9.6	-8.1	-9.5	-5.5	-7.0	-6.3	-8.9	-6.6	-3.3	0.7
Heart attack/myocardial infarction (self-reported)	6.3	8.2	16.6	2.7	-2.9	-3.7	-2.6	-1.5	-1.8	-3.4	-3.3	-3.6	-3.8	-2.4	-2.5	-2.5	-4.1	-3.1	-1.4	1.1
Heart attack	6.0	7.7	16.6	2.9	-2.9	-3.6	-2.3	-1.3	-1.5	-3.2	-3.3	-3.7	-3.7	-2.2	-2.3	-2.4	-4.1	-2.9	-1.2	1.1
Coronary Artery Disease (CAD)	5.4	6.4	24.6	3.1	-1.8	-1.9	-1.0	-0.5	-0.7	-3.1	-3.4	-4.2	-5.0	-1.2	-2.1	-1.6	-3.5	-1.9	-0.3	1.3
Bipolar Disorder (2011)	5.0	4.8	10.9	-0.3	-1.5	-1.7	-1.9	-2.1	-2.5	-3.3	-2.2	-0.9	-1.7	-2.4	-2.6	-2.4	-2.2	-2.5	-2.4	2.6
Fluid intelligence score	4.9	10.2	20.6	-1.3	2.9	3.6	3.5	2.7	2.8	4.0	3.7	2.4	4.5	3.2	3.4	3.1	4.0	3.7	2.4	0.6
Alcohol intake versus 10 years previously	4.8	7.2	11.5	0.5	-3.4	-2.2	-1.2	-2.9	-2.8	-2.7	-3.2	-1.4	-3.4	-3.1	-3.2	-3.2	-2.9	-3.1	-2.7	1.2
HbA1C	4.7	5.3	15.5	2.0	-2.8	-1.6	-0.6	-2.0	-1.9	-2.1	-2.9	-2.7	-3.9	-2.5	-2.1	-2.6	-3.4	-0.3	-1.4	0.6
Schizophrenia (2018)	4.5	9.4	25.6	4.6	-3.3	-3.3	-2.1	-0.9	-0.8	-3.6	-3.4	-5.1	-3.5	-1.9	-1.6	-2.1	-5.0	-2.3	-0.7	2.8
Verbal and Numeric Reasoning (VNR)	4.5	10.8	27.7	-2.8	3.3	3.7	3.3	2.0	2.2	3.6	4.0	3.7	5.3	2.8	3.1	2.9	4.5	3.3	1.7	0.8
Pulse rate, automated reading	4.5	14.4	30.4	2.0	-3.9	-3.5	-3.2	-2.8	-2.8	-5.5	-5.1	-4.6	-3.0	-3.5	-3.9	-3.7	-5.5	-4.5	-2.9	1.4
Supplements: Glucosamine	4.4	5.8	10.9	-0.8	2.4	2.6	1.9	2.6	2.3	2.1	3.3	1.5	2.8	2.7	2.4	3.0	2.8	2.8	2.2	0.6
Hip circumference	4.2	18.0	37.5	-1.2	3.8	2.8	2.1	3.8	4.1	6.1	5.6	3.0	4.2	4.6	5.3	4.9	5.0	4.9	3.6	-4.0
Major Depression (MDD)	4.0	4.8	8.1	0.3	1.6	2.7	1.0	2.8	2.4	2.3	2.3	0.6	2.8	2.7	2.6	2.5	2.2	2.8	2.5	0.0
Pulse rate	4.0	6.7	19.0	2.3	-2.4	-2.8	-1.8	-1.2	-0.9	-3.5	-3.8	-4.4	-2.8	-1.6	-1.9	-2.2	-4.2	-2.5	-1.0	0.0
Schizophrenia (2014)	3.9	8.7	25.6	4.6	-3.4	-3.5	-2.0	-0.4	-0.4	-3.5	-3.2	-5.1	-2.9	-1.5	-1.4	-1.8	-4.8	-2.1	-0.4	2.7
Alcohol intake frequency.	3.8	8.9	18.7	0.2	-3.8	-2.2	-1.3	-3.4	-3.0	-3.6	-3.5	-1.2	-4.3	-3.1	-3.5	-3.3	-3.0	-3.6	-3.0	-0.2
Alcohol drinker status: Never	3.8	4.5	10.0	-0.0	-3.2	-2.0	-1.5	-2.4	-2.2	-2.7	-1.9	-0.2	-2.2	-2.3	-2.3	-2.5	-1.8	-2.7	-2.5	-0.5
Lung cancer (father)	3.7	4.3	9.7	-0.3	-1.9	-2.3	-3.1	-2.2	-2.2	-2.3	-2.0	-0.4	-2.2	-2.2	-2.0	-1.9	-1.6	-2.2	-2.1	-2.3
Vitamin and mineral supplements	3.6	4.9	8.4	0.6	-2.9	-2.6	-2.4	-2.0	-2.2	-1.9	-2.5	-0.9	-1.9	-2.6	-2.4	-2.7	-2.5	-2.8	-1.9	0.6
Multivitamins +/- minerals	3.6	4.6	9.0	-0.4	3.0	2.7	2.9	2.2	2.2	1.7	2.1	0.8	1.8	2.5	2.1	2.5	2.4	2.6	1.9	-0.2
Bipolar Disorder or Schizophrenia	3.5	8.6	17.6	3.4	-3.6	-2.8	-1.8	-1.4	-1.3	-4.2	-3.4	-3.9	-2.7	-2.2	-1.9	-2.5	-4.2	-2.5	-1.4	4.1
Medication for hormone replacement therapy	3.5	3.9	7.9	0.1	2.7	1.9	0.9	2.2	2.5	1.3	2.4	0.2	1.3	2.6	2.3	2.8	1.6	2.1	2.3	-1.3
Triglycerides	3.2	5.2	12.2	1.1	-2.7	-1.2	-1.3	-2.0	-2.1	-3.0	-3.5	-2.0	-2.8	-2.3	-2.5	-2.6	-2.8	-2.4	-1.7	1.0
Impedance of leg (left)	3.2	15.4	33.2	4.0	-4.2	-5.0	-3.4	-2.2	-2.3	-4.6	-4.2	-5.0	-5.8	-3.2	-3.6	-3.4	-5.6	-3.8	-1.9	0.5
Angina (self-reported)	3.2	4.2	9.4	1.2	-1.6	-1.1	-0.9	-1.9	-1.9	-3.1	-2.3	-1.6	-3.0	-2.1	-2.5	-2.0	-2.3	-2.4	-1.5	1.9
Qualifications: NVQ or HND or HNC or equivalent	3.2	3.9	7.4	0.6	-2.3	-2.5	-2.6	-1.8	-2.0	-1.1	-2.1	-1.1	-2.7	-2.1	-2.0	-2.2	-2.5	-2.1	-1.7	-0.4
Intelligence (Savage-Jansen 2018)	3.1	9.6	24.9	-3.0	2.9	3.9	3.5	1.7	1.9	2.8	3.5	3.7	5.0	2.6	2.7	2.5	4.3	3.1	1.3	1.7
Angina	3.1	4.0	9.0	1.2	-1.6	-1.0	-0.6	-1.8	-1.9	-3.0	-2.4	-1.6	-2.8	-2.1	-2.4	-2.0	-2.2	-2.4	-1.4	2.0
Reaction Time	3.0	5.7	13.1	3.1	-2.4	-3.0	-2.5	-1.0	-1.6	-2.5	-2.5	-3.1	-2.3	-2.1	-2.0	-1.9	-3.6	-2.6	-1.2	1.3
Blood White Count	3.0	22.4	57.0	6.5	-4.2	-3.6	-2.1	-1.6	-1.9	-6.5	-6.4	-7.5	-7.0	-3.2	-3.5	-3.4	-7.0	-4.3	-1.4	2.1
Average weekly champagne plus white wine intake	3.0	4.1	9.5	0.2	3.1	1.8	1.8	2.1	2.3	2.1	2.6	0.3	1.8	2.2	2.2	2.5	2.0	2.1	1.9	-0.7
Prostate Cancer	2.9	4.0	8.0	1.6	-2.1	-2.5	-1.7	-1.2	-1.7	-2.3	-2.6	-2.4	-2.2	-1.8	-1.8	-2.1	-2.8	-1.9	-1.5	0.8
Lung FEV1/FVC ratio	2.9	14.8	47.9	3.8	-2.5	-0.8	0.4	-2.5	-2.7	-4.5	-5.8	-4.7	-6.9	-3.2	-4.3	-3.7	-5.2	-3.6	-1.6	2.8
Diabetes diagnosed by doctor	2.9	4.8	8.6	1.3	-2.9	-2.7	-1.6	-1.5	-1.5	-2.4	-2.9	-2.0	-2.2	-2.1	-1.8	-2.4	-2.6	-2.8	-1.6	1.6
Townsend deprivation index at recruitment	2.8	4.0	7.6	-0.6	2.4	2.0	1.1	1.7	1.7	2.4	2.5	1.8	1.1	2.3	2.0	2.4	2.7	2.3	1.7	-1.6
Bilateral oophorectomy (both ovaries removed)	2.8	3.2	13.0	-1.5	-1.0	-2.9	-3.6	-1.8	-1.9	-1.9	-0.5	0.6	-0.5	-1.8	-1.2	-1.4	-0.9	-2.1	-2.5	-0.5
Impedance of leg (right)	2.7	12.9	31.6	3.6	-3.7	-4.3	-2.8	-2.1	-2.1	-4.2	-4.0	-4.5	-5.6	-2.9	-3.5	-3.1	-5.1	-3.6	-1.7	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.1	6.7	0.0	1.7	2.0	1.5	1.7	1.8	1.3	2.6	1.2	1.6	1.9	2.1	2.3	2.1	2.2	1.5	0.2
Supplements: Calcium	2.6	2.8	8.0	0.1	1.7	0.3	0.6	1.7	2.0	2.1	2.2	0.2	1.4	2.0	2.0	2.0	1.2	1.7	1.5	-2.8
Schizophrenia vs Biploar Disorder	2.5	3.2	16.8	3.7	-0.1	-1.0	-0.1	1.6	1.8	-0.6	-1.1	-4.1	-1.8	1.0	0.6	0.9	-2.4	0.5	1.9	-1.1
Unable to work because of sickness or disability	2.5	3.2	7.7	0.5	-1.6	-2.8	-2.1	-1.6	-1.7	-2.1	-1.6	-1.1	-2.4	-1.8	-1.5	-1.8	-1.8	-2.3	-1.6	-0.9
Alzheimer’s Disease (in mother)	2.4	2.8	11.8	-2.6	0.5	2.8	1.0	-0.4	-0.3	0.6	1.3	3.4	2.4	0.2	-0.1	0.3	2.8	0.5	-0.4	1.7
Sensitivity / hurt feelings	2.4	4.2	10.0	2.2	-1.4	-3.2	-2.9	-0.5	-1.8	-1.8	-2.3	-2.6	-1.4	-1.7	-1.2	-1.9	-2.8	-2.2	-1.4	1.6
Diabetes (mother)	2.4	3.1	8.5	0.6	-1.5	-2.2	-1.8	-1.3	-1.2	-2.9	-2.1	-1.5	-2.9	-1.5	-1.2	-1.5	-1.8	-1.6	-1.2	1.5
Age when periods started (menarche)	2.4	5.8	11.5	-0.5	-1.2	-1.6	-0.7	-3.1	-3.3	-2.4	-2.9	-0.3	-3.0	-3.1	-3.4	-3.0	-1.9	-2.9	-2.5	-1.0
Diabetes (self-reported)	2.4	3.7	8.2	2.0	-2.9	-2.6	-1.3	-0.8	-1.0	-1.8	-2.4	-2.2	-1.5	-1.6	-1.3	-1.9	-2.5	-2.5	-1.2	1.7
Pulse wave reflection index	2.4	3.0	10.2	-2.4	1.9	2.3	1.3	0.4	0.2	2.1	2.1	3.2	1.3	0.8	0.6	1.2	2.8	1.7	0.3	-0.1
Ever had hysterectomy (womb removed)	2.3	2.6	7.8	-0.7	-1.0	-1.7	-2.8	-1.7	-2.0	-2.5	-0.8	0.3	-1.8	-1.8	-1.5	-1.4	-0.8	-1.6	-2.1	0.6
Myopia	2.3	3.4	7.5	2.0	-2.1	-1.5	-1.1	-0.9	-1.0	-2.1	-2.7	-2.7	-1.5	-1.5	-1.3	-1.9	-2.7	-1.8	-0.9	1.9
Ovarian Cancer	2.2	2.9	5.8	0.7	-1.7	-2.4	-2.1	-1.6	-1.2	-2.4	-1.4	-1.3	-1.6	-1.8	-1.3	-1.8	-2.1	-2.1	-1.7	0.2
Qualifications: None of the above	2.2	4.7	11.5	1.0	-2.1	-2.7	-2.6	-1.9	-2.1	-2.1	-1.7	-1.2	-3.4	-2.2	-2.2	-1.8	-2.3	-2.6	-1.4	-2.2
Time employed in main current job	2.2	2.6	7.4	2.2	-0.6	-2.4	-2.6	0.2	-0.1	-2.3	-1.2	-2.7	-1.9	-0.6	-0.4	-0.4	-2.6	-1.0	-0.1	-0.0
Depression (self-reported)	2.2	2.6	6.5	-0.3	2.0	0.8	0.8	1.7	1.4	1.9	2.5	1.1	2.4	1.5	1.7	1.8	1.7	1.9	1.3	0.6
Mean time to correctly identify matches	2.2	4.2	11.8	3.4	-2.0	-2.5	-2.2	-0.2	-0.6	-2.2	-1.9	-3.3	-1.4	-1.3	-1.4	-1.0	-3.4	-1.9	-0.4	1.3
Alcohol drinker status: Previous	2.2	2.5	4.9	-2.1	1.1	1.5	1.8	0.5	1.0	2.1	1.8	2.1	1.4	1.4	1.1	1.4	2.2	1.2	0.8	-2.0
Allergy or Eczema	2.1	5.6	15.1	3.2	-2.6	-2.8	-1.4	-0.6	-0.4	-3.4	-2.7	-3.9	-2.8	-1.3	-0.7	-1.4	-3.6	-2.0	-0.8	2.1
Body mass index (BMI)	2.1	8.8	16.2	-0.3	3.1	2.3	2.2	3.0	3.0	4.0	3.6	1.6	2.8	3.4	3.7	3.5	3.3	3.2	2.8	-2.5
Nervous feelings	2.1	4.0	8.5	1.4	-1.2	-2.6	-1.4	-1.1	-1.8	-2.9	-1.4	-1.6	-2.9	-1.7	-1.8	-1.8	-2.5	-2.2	-1.6	2.8
Medication: Bendroflumethiazide	2.1	3.2	13.4	3.7	0.9	-0.1	-0.2	2.8	2.2	1.0	0.4	-2.8	0.7	1.9	1.9	1.8	-1.0	1.1	2.4	-0.3
Type 2 Diabetes (T2D) (2012)	2.0	2.3	4.9	0.1	-1.9	-1.2	-0.4	-1.7	-1.5	-2.0	-1.8	-0.5	-1.4	-1.6	-1.8	-1.6	-2.2	-1.8	-1.7	0.3
Medication: Atenolol	2.0	2.5	9.4	2.8	-0.8	-1.7	-1.9	0.3	-0.0	-1.9	-1.6	-3.1	-1.9	-0.3	-0.7	-0.5	-2.5	-1.1	0.3	-0.4
Alzheimer’s Disease (including proxy)	1.9	2.7	11.8	-2.9	1.0	2.6	0.5	-0.4	-0.5	0.4	1.6	3.4	2.1	0.1	-0.1	0.4	2.6	0.5	-0.5	1.8
Arm fat percentage (left)	1.9	7.5	13.8	-0.3	2.2	1.3	1.8	2.6	3.0	3.7	3.6	1.5	2.6	3.2	3.5	3.2	3.1	2.9	2.5	-3.0
Mineral and other dietary supplements	1.9	2.5	6.2	0.8	-2.1	-1.1	-0.9	-1.4	-1.7	-0.5	-2.5	-0.8	-1.9	-1.9	-1.7	-2.3	-1.7	-2.0	-1.2	-0.2
Osteoporosis (self-reported)	1.9	2.4	12.5	-3.5	0.8	0.6	-0.2	-1.3	-0.7	0.6	1.9	3.2	1.4	-0.2	0.1	0.3	2.3	0.0	-1.5	-0.8
Number of self-reported non-cancer illnesses	1.9	3.4	15.3	3.8	0.1	-2.6	-2.0	1.6	0.9	-1.8	-0.4	-3.9	-1.1	0.4	0.8	0.7	-2.5	-0.5	0.8	0.2
Pain experienced in last month	1.9	3.1	11.4	-3.1	0.3	1.4	1.4	-0.4	0.4	2.4	1.7	3.4	2.6	0.5	0.5	0.6	3.0	1.1	0.0	-1.2
Body Mass Index (BMI) (2010)	1.8	2.5	5.4	-2.3	2.3	1.5	0.1	0.5	0.5	1.5	2.2	2.2	2.3	1.1	1.2	1.4	2.2	1.3	0.1	-0.6
Type 2 Diabetes (T2D) (2018)	1.8	3.5	7.2	2.3	-2.5	-2.5	-0.8	-0.5	-0.6	-1.8	-2.6	-2.7	-2.4	-1.1	-1.1	-1.7	-2.7	-1.8	-0.5	1.1
Eye problems/disorders: Diabetes related eye disease	1.8	1.9	4.1	-0.6	-1.6	-0.9	-0.4	-1.8	-1.4	-1.4	-2.0	-0.2	-1.2	-1.6	-1.7	-1.8	-1.1	-2.0	-1.6	0.4
Maternal smoking around birth	1.8	2.6	9.4	-2.1	1.1	1.4	0.9	0.2	0.3	1.8	2.4	3.1	2.2	0.9	0.7	1.1	2.5	0.8	0.2	-1.6
Mouth/teeth dental problems: Dentures	1.8	3.0	6.1	1.2	-1.2	-2.2	-2.4	-1.3	-1.6	-1.8	-1.7	-2.0	-2.2	-1.5	-1.6	-1.3	-2.5	-1.8	-1.2	-0.9
Qualifications: College or University degree	1.8	5.7	19.3	-0.8	2.0	1.6	2.3	2.5	2.5	2.7	2.6	1.2	4.4	2.6	2.7	2.3	2.3	2.8	1.8	0.8
Illnesses of siblings: Diabetes	1.8	2.3	8.4	2.6	-0.9	-2.3	-0.7	0.2	0.2	-2.3	-1.1	-2.9	-1.5	-0.5	-0.2	-0.5	-2.4	-1.0	0.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	11.1	-0.2	-2.5	-1.2	-0.3	-2.3	-1.7	-1.0	-3.0	-1.1	-3.3	-2.2	-2.4	-2.4	-1.9	-1.6	-1.4	-0.9
Ever depressed for a whole week	1.8	2.2	4.3	-1.4	-1.7	-1.3	-1.6	-2.0	-2.0	-1.2	-1.3	0.8	-0.6	-1.8	-1.8	-2.1	-0.6	-1.6	-1.8	0.3
Arm fat percentage (right)	1.7	6.7	12.2	-0.4	2.1	1.1	1.5	2.4	2.9	3.4	3.5	1.5	2.5	3.0	3.4	3.0	2.9	2.7	2.3	-3.0
Prospective memory result	1.7	2.1	6.9	-0.8	-1.4	-1.6	-2.6	-1.6	-1.6	-1.6	-0.5	0.5	-1.3	-1.6	-1.4	-1.1	-0.8	-1.9	-1.7	-0.5
Length of working week for main job	1.7	1.8	7.3	2.1	-0.7	-1.6	-0.7	0.7	0.8	0.2	-1.2	-2.6	-1.5	0.3	0.3	-0.2	-1.8	-0.1	0.9	-2.7
Overall health rating	1.7	3.6	19.1	4.0	-1.0	-1.8	0.2	1.0	0.8	-1.2	-1.6	-4.4	-2.0	0.2	-0.2	-0.2	-2.9	-1.0	0.9	1.2
Ever had bowel cancer screening	1.7	2.0	7.4	-2.2	0.9	1.4	-0.2	0.1	0.1	1.0	1.8	2.6	2.7	0.4	0.7	0.7	2.1	0.7	-0.3	1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	3.6	-0.4	1.6	1.5	1.5	1.1	1.3	1.9	1.3	0.3	1.1	1.4	1.2	1.6	1.2	1.6	1.4	-1.7
Blood Red Count	1.6	15.5	35.6	2.1	-2.8	-6.0	-5.9	-2.4	-2.6	-3.0	-4.4	-4.6	-5.0	-3.1	-2.4	-3.1	-5.2	-3.1	-2.1	-5.2
BMI	1.6	9.1	16.7	-0.5	3.4	3.2	2.5	2.9	2.8	3.5	4.1	2.1	3.1	3.4	3.7	3.5	3.6	3.2	2.5	-0.6
Fed-up feelings	1.6	3.0	7.6	0.4	-0.3	-2.0	-1.9	-1.3	-2.1	-2.8	-1.4	-1.1	-1.6	-1.6	-1.3	-1.5	-1.8	-2.1	-2.0	2.2
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	4.2	-1.8	-1.0	-0.3	-0.2	-2.0	-1.6	-1.6	-0.4	1.2	-1.3	-1.4	-1.7	-1.1	0.1	-1.3	-1.8	0.2
Medication: Ramipril	1.6	2.1	10.2	3.2	0.9	-0.9	-0.1	1.3	0.9	-0.8	-1.1	-3.2	-1.2	0.4	0.6	0.2	-1.9	-0.1	1.2	1.5
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	6.2	-1.2	2.3	1.8	2.5	0.9	1.3	1.5	1.4	1.3	2.0	1.5	1.7	1.5	1.9	2.0	0.9	0.4
Medication: Blood pressure	1.6	2.8	8.5	2.8	1.9	-0.6	-0.9	2.9	2.0	0.8	1.3	-1.9	0.3	1.9	1.8	1.9	-0.2	1.2	2.3	0.4
Mother’s age at death	1.6	2.0	5.0	-0.7	0.4	1.4	1.3	0.9	1.7	1.5	1.5	1.0	2.2	1.5	1.8	1.2	1.9	1.7	1.2	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.1	7.6	2.7	-0.2	-1.3	-0.1	0.6	-0.2	-1.6	-1.0	-2.6	-1.6	-0.3	-0.2	-0.4	-2.1	-0.5	0.1	2.8
Chronic bronchitis/emphysema (father)	1.5	1.8	4.2	-0.1	1.2	2.0	1.5	1.2	1.5	1.2	1.5	0.7	0.4	1.6	1.4	1.6	1.6	1.4	1.3	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	4.6	1.7	2.2	0.8	0.4	1.8	1.2	0.7	1.7	-0.4	0.4	1.4	1.4	1.6	0.7	1.7	1.6	0.2
Smoking status: Previous	1.5	2.2	5.4	-1.7	1.5	1.9	1.4	0.6	0.6	2.3	1.6	2.2	1.7	1.0	0.9	1.0	2.3	1.2	0.7	0.2
Heart disease (siblings)	1.5	1.9	7.7	2.4	-0.4	-1.0	0.1	0.5	0.3	-1.7	-1.4	-2.8	-1.7	0.0	-0.7	-0.4	-2.2	-0.7	0.4	1.6
Average weekly spirits intake	1.4	1.7	5.3	2.3	-0.5	-1.9	-1.0	0.1	-0.2	-1.2	-1.3	-2.3	-2.3	-0.3	-0.5	-0.6	-1.9	-0.6	0.3	-0.0
Frequency of depressed mood in last 2 weeks	1.4	1.9	9.6	1.3	-1.1	-1.5	-0.5	-0.4	-0.9	-1.9	-1.1	-1.5	-1.1	-1.1	-0.8	-1.0	-1.7	-1.3	-0.9	3.1
Hayfever, allergic rhinitis or eczema	1.4	3.1	8.5	1.9	-1.9	-2.5	-1.4	-0.6	-0.2	-2.9	-2.1	-2.7	-1.9	-1.0	-0.2	-1.0	-2.6	-1.5	-0.8	1.2
Past tobacco smoking	1.4	2.7	6.1	1.4	-2.1	-1.9	-1.0	-1.0	-1.0	-2.5	-2.1	-1.9	-1.8	-1.4	-1.4	-1.6	-2.3	-1.4	-1.0	0.4
Headache pain in last month	1.4	2.5	7.6	2.6	-1.4	-0.6	-0.7	-0.2	-0.7	-1.5	-2.4	-2.8	-1.5	-0.9	-1.1	-1.3	-2.7	-1.3	-0.2	1.1
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	9.5	2.3	1.2	1.2	3.1	2.1	2.0	0.8	0.6	-1.3	0.1	1.8	1.1	1.6	0.1	1.7	2.3	1.7
Health satisfaction	1.4	1.8	8.4	2.9	-0.1	-2.0	0.1	0.7	0.4	-1.1	-0.4	-2.5	-1.0	0.0	-0.0	0.1	-1.7	-0.9	0.2	2.0
Had major operations	1.4	1.7	6.8	-0.6	0.6	1.3	0.8	1.0	0.9	0.8	1.5	1.4	2.6	1.1	1.5	0.9	1.8	1.1	0.6	1.6
Knee pain experienced in last month	1.4	2.1	6.8	2.3	-1.6	-1.0	-1.3	-0.1	-0.5	-1.6	-1.4	-2.6	-1.1	-0.8	-0.8	-0.9	-2.5	-1.2	-0.2	1.5
Commuting to job workplace: Walk	1.4	1.5	3.2	-0.4	1.2	1.8	0.9	1.0	1.3	1.2	1.1	0.6	0.6	1.4	1.4	1.5	1.3	1.6	1.4	-0.8
Breast cancer (self-reported)	1.4	1.7	4.1	-1.8	-0.3	-1.2	-1.5	-2.0	-1.8	-0.7	-1.0	0.4	-0.7	-1.6	-1.2	-1.4	-0.8	-1.3	-2.0	-0.3
Arm fat mass (left)	1.4	5.8	12.7	-0.4	2.0	1.4	1.6	2.2	2.6	3.6	2.7	1.0	1.8	2.8	3.0	2.7	2.5	2.6	2.3	-3.5
Hypothyroidism (self reported)	1.3	3.1	11.2	3.4	1.1	0.2	2.6	2.1	2.1	0.1	0.2	-2.5	-0.8	1.7	1.2	1.5	-0.7	1.5	2.3	1.6
Lung FVC	1.3	6.5	20.2	-3.1	1.6	3.7	2.1	0.6	0.3	2.5	2.5	4.5	4.0	1.1	1.0	1.2	4.2	2.0	0.4	1.9
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	3.6	1.1	-0.8	-1.2	-0.0	-0.8	-0.9	-1.6	-1.4	-1.5	-1.5	-1.1	-1.5	-1.2	-1.9	-1.6	-0.8	0.5
Medication: Levothyroxine sodium	1.3	2.2	9.5	3.1	0.5	0.3	2.4	1.7	1.4	0.1	0.1	-2.1	-1.0	1.3	0.6	1.1	-0.9	1.0	1.8	1.7
Pain all over the body in last month	1.3	1.4	5.5	1.6	-0.6	-1.9	-1.2	0.5	0.5	-0.7	-0.3	-2.3	-1.4	0.0	0.0	0.1	-1.7	-0.4	0.5	-1.8
Arm fat mass (right)	1.3	5.5	12.4	-0.3	2.0	1.2	1.5	2.1	2.5	3.4	2.6	0.9	1.6	2.8	2.9	2.7	2.4	2.5	2.3	-3.5
Comparative height size at age 10	1.3	6.9	23.6	0.3	-2.5	-3.0	-2.4	-2.8	-1.8	-2.5	-3.2	-2.9	-4.9	-2.2	-2.4	-2.3	-3.3	-2.2	-1.7	-1.9
Number of full sisters	1.3	1.5	3.7	0.4	-1.9	-0.5	-0.4	-1.3	-0.8	-1.0	-1.9	-0.7	-1.7	-1.1	-1.6	-1.4	-1.3	-1.1	-0.6	-1.7
Age started oral contraceptive pill	1.3	1.6	5.9	1.2	-1.4	-1.8	-2.4	-0.3	-0.1	-1.8	-1.3	-2.1	-0.6	-0.5	-0.1	-0.6	-1.9	-0.5	-0.3	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.3	1.5	4.4	-0.8	0.9	1.1	0.7	0.9	1.2	1.0	2.1	1.2	1.6	1.2	1.2	1.6	1.5	1.2	0.6	-1.3
Breast Cancer	1.2	2.9	12.7	-3.0	1.6	1.9	1.4	-0.2	0.2	1.5	1.8	3.6	0.6	0.6	0.5	0.9	2.9	1.3	-0.1	-1.5
Fasting Glucose	1.2	1.5	4.4	-0.1	1.1	1.8	1.2	1.1	0.8	0.6	1.3	1.1	1.4	0.9	1.0	0.9	1.4	1.6	0.7	2.1
Ever used hormone-replacement therapy (HRT)	1.2	1.6	5.2	-1.4	1.5	1.1	-0.6	0.5	0.2	0.2	1.8	2.2	2.3	0.8	0.9	1.1	2.0	0.4	-0.1	0.2
Medication: Metformin	1.2	1.7	4.3	0.8	-1.3	-1.5	-0.8	-0.8	-0.8	-2.0	-1.6	-1.0	-2.1	-1.1	-1.1	-1.3	-1.4	-1.5	-0.8	0.8
Trunk fat percentage	1.2	4.8	16.6	1.1	1.3	-0.4	0.6	2.3	2.7	2.8	2.5	-0.3	0.6	2.7	2.7	2.6	1.3	2.2	2.4	-4.1
High blood pressure (mother)	1.2	1.7	4.0	-0.7	-0.8	-1.9	-2.0	-1.3	-1.6	-1.8	-1.2	0.2	-0.6	-1.5	-0.9	-1.4	-0.9	-1.6	-1.8	-0.1
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	8.8	3.0	0.3	-1.3	-1.0	1.5	0.4	-1.4	-0.2	-2.6	-0.8	0.3	0.4	0.4	-1.7	-0.3	0.6	2.0
Medication: Lansoprazole	1.2	1.3	4.7	1.0	2.2	-0.3	-0.8	1.2	0.8	0.7	1.3	0.2	0.0	1.0	1.2	1.4	0.7	0.9	1.2	-2.1
Illnesses of mother	1.2	1.5	6.3	0.3	0.5	1.5	2.5	0.8	1.2	2.2	1.2	0.6	1.1	1.0	0.9	1.0	1.2	1.4	1.2	-0.1
Comparative body size at age 10	1.2	3.3	9.7	-2.7	1.9	2.1	1.9	0.5	0.7	1.1	1.8	2.8	2.2	1.2	1.7	1.1	3.1	1.5	0.5	0.8
Diastolic blood pressure, automated reading	1.2	3.9	8.8	2.7	1.1	-0.7	-0.1	2.7	2.7	1.2	0.5	-2.9	1.0	2.0	1.9	1.9	-0.8	1.8	2.7	-3.0
Impedance of whole body	1.2	6.3	13.1	2.0	-3.2	-3.6	-2.3	-1.7	-1.5	-2.8	-2.4	-2.6	-3.6	-2.2	-2.6	-2.3	-3.3	-2.4	-1.4	-0.1
Bipolar Disorder (2018)	1.1	1.7	9.7	-0.4	-1.5	-0.4	-0.3	-1.1	-1.1	-2.2	-1.1	0.1	-0.2	-1.1	-1.0	-1.4	-0.4	-1.1	-1.3	3.1
Height	1.1	20.9	54.9	1.5	-3.7	-5.5	-3.5	-3.9	-3.0	-2.8	-5.8	-5.5	-7.4	-3.6	-4.5	-3.8	-6.4	-3.6	-1.9	-6.3
Systolic Blood Pressure	1.1	5.8	27.1	5.1	1.1	-2.2	-1.3	3.0	2.0	-0.3	-1.0	-5.2	-0.5	1.3	1.4	1.2	-3.0	0.7	2.6	-1.1
Number of treatments/medications taken	1.1	1.9	7.0	2.6	1.5	-0.8	-0.6	1.9	1.4	-0.4	1.2	-2.2	-0.5	1.3	1.4	1.8	-1.0	0.7	1.5	0.2
Relative age voice broke	1.1	1.7	5.5	-1.8	1.0	1.4	0.1	0.4	0.8	1.6	1.2	1.3	1.7	0.9	1.1	1.2	1.5	1.2	0.6	-2.3
Had other major operations	1.1	1.3	5.2	-1.7	-0.4	-2.0	-1.2	-1.3	-0.9	-1.1	0.4	1.0	1.0	-0.8	-0.5	-0.5	0.0	-0.8	-1.3	-2.3
Loud music exposure frequency	1.1	1.2	4.7	0.2	-0.9	-1.7	-2.2	-1.0	-1.1	-0.1	-0.5	0.1	-0.9	-1.2	-0.8	-1.0	-0.8	-0.9	-1.0	-1.8
Body fat percentage	1.1	4.5	12.2	1.1	1.4	-0.3	0.6	2.3	2.6	2.7	2.6	-0.1	0.8	2.6	2.8	2.6	1.4	2.1	2.3	-3.5
Friendships satisfaction	1.1	1.4	3.6	1.0	1.9	0.6	1.2	1.5	1.4	0.8	0.9	-0.6	1.0	1.5	1.4	1.5	0.5	1.3	1.4	0.1
Tinnitus: Yes, now most or all of the time	1.1	1.3	10.4	-0.5	-0.6	0.9	1.7	-0.3	-0.7	0.2	0.2	1.2	1.6	-0.5	-0.7	-0.6	1.1	-0.5	-0.6	3.2
Depression (Nagel 2018)	1.0	1.6	13.9	1.2	-0.0	-1.0	-0.6	0.2	-0.4	-1.9	-0.7	-1.4	-0.6	-0.6	-0.4	-0.5	-1.3	-0.7	-0.6	3.7
Heel T-Score	1.0	8.0	18.3	0.4	2.5	4.0	3.1	2.7	2.4	4.3	3.3	2.4	3.0	2.5	2.5	2.8	3.5	2.9	2.7	0.4
Systolic blood pressure, automated reading	1.0	3.0	12.7	3.3	0.6	-2.2	-1.6	1.8	1.5	-0.7	-0.4	-3.6	-0.3	0.7	1.0	0.9	-2.2	0.4	1.6	-1.8
Leg predicted mass (left)	1.0	5.1	13.4	-1.5	2.1	2.3	2.5	1.3	1.9	3.7	1.6	1.4	1.4	2.3	2.1	2.1	2.5	2.7	2.0	-3.5
Financial difficulties in last 2 years	1.0	1.4	3.5	-1.6	-1.1	0.0	-0.4	-1.9	-1.5	-0.5	-1.1	1.2	-0.4	-1.4	-1.3	-1.7	0.0	-1.0	-1.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	5.4	1.0	1.2	2.3	2.1	1.0	0.7	0.7	-0.3	-0.7	-0.5	0.8	0.6	0.6	0.4	0.9	1.2	1.3
Standing height	1.0	9.7	27.6	0.5	-3.1	-2.8	-1.8	-3.1	-2.0	-2.0	-4.7	-3.6	-5.2	-2.6	-3.2	-2.9	-4.0	-2.1	-1.4	-4.0
Tense / ‘highly strung’	1.0	1.7	9.8	3.1	0.3	-0.8	-0.8	1.9	0.7	-0.2	0.5	-2.2	-0.6	0.8	0.8	0.7	-1.3	0.0	1.1	1.8
Birth weight of first child	1.0	1.8	10.6	-0.9	-1.4	1.8	2.1	0.3	0.7	0.0	0.9	1.8	1.7	0.1	0.4	0.1	1.3	0.4	-0.3	3.3
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	7.5	-2.7	-1.0	1.2	1.0	-1.8	-1.0	0.3	-0.7	2.0	0.9	-0.9	-0.7	-1.1	0.7	-0.3	-1.5	-1.2
High blood pressure (siblings)	1.0	1.4	2.6	0.2	1.3	0.1	0.1	1.3	1.4	1.0	1.3	0.1	1.2	1.5	1.6	1.6	0.9	1.5	1.5	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	2.3	0.3	-1.4	-0.7	-0.1	-1.1	-1.4	-0.6	-0.9	-0.0	-0.8	-1.5	-1.4	-1.4	-1.0	-1.4	-1.2	0.9
Whole body fat mass	1.0	4.0	14.0	0.6	1.4	0.3	0.8	2.0	2.4	2.9	2.0	-0.1	0.5	2.4	2.5	2.3	1.4	2.1	2.2	-3.7
Leg fat mass (right)	1.0	3.7	8.8	0.8	1.5	0.5	1.1	2.0	2.3	2.8	2.0	-0.1	0.6	2.4	2.5	2.3	1.4	2.1	2.3	-3.0
Supplements: Vitamin C	1.0	1.2	2.8	1.4	1.7	-0.2	-0.3	1.0	1.0	0.1	0.7	-1.6	-0.5	1.2	1.1	1.3	-0.3	1.0	1.2	-1.7
Supplements: Fish oil (including cod liver oil)	1.0	1.4	4.5	-0.5	2.1	0.6	0.4	1.2	1.2	0.2	1.4	0.1	1.3	1.5	1.3	1.6	1.0	1.6	1.0	0.7
High cholesterol (Self-reported)	1.0	1.7	8.9	2.0	-0.4	-0.1	0.3	0.1	-0.5	-2.1	-0.7	-1.7	-1.9	-0.6	-1.1	-0.2	-1.3	-0.8	-0.2	3.0
Medication: Atorvastatin	1.0	1.3	7.6	2.8	0.3	-0.3	0.5	1.3	0.8	-0.1	-0.7	-2.5	-0.8	0.6	0.3	0.5	-1.1	-0.2	1.1	0.7
Lupus	0.9	1.4	3.9	1.6	1.0	-0.7	-0.5	1.0	1.2	0.3	0.1	-1.8	-2.0	1.0	1.2	0.9	-0.5	1.0	1.3	-1.8
Cardiovascular Disease	0.9	2.9	11.5	3.4	1.2	-0.0	0.3	2.8	1.8	0.1	0.2	-3.0	0.4	1.7	1.7	1.6	-0.8	1.2	2.2	1.0
Leg fat-free mass (left)	0.9	5.0	13.0	-1.4	2.1	2.3	2.4	1.3	1.9	3.6	1.5	1.3	1.4	2.2	2.1	2.1	2.4	2.7	2.0	-3.5
Average weekly fortified wine intake	0.9	1.1	2.2	0.0	1.4	0.3	0.0	1.1	1.2	0.4	1.3	-0.0	1.5	1.3	1.4	1.5	0.8	1.3	1.0	-0.4
High blood pressure	0.9	2.4	7.5	2.6	1.4	-0.8	-1.4	2.3	1.6	-0.1	0.3	-2.7	0.9	1.5	1.6	1.5	-1.0	0.7	1.7	-1.6
Trunk fat mass	0.9	4.0	18.3	0.7	1.1	-0.1	0.7	1.8	2.4	2.8	1.9	-0.4	0.3	2.4	2.4	2.2	1.2	2.1	2.2	-4.3
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	4.2	2.0	-0.5	0.4	1.5	0.9	0.7	0.2	-0.6	-2.0	-0.5	0.5	0.3	0.2	-1.2	0.5	1.1	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	3.3	-0.2	1.4	1.2	0.5	1.2	0.7	1.0	1.4	1.0	1.8	1.0	1.1	0.8	1.4	1.2	0.8	1.6
Peak expiratory flow (PEF)	0.9	2.1	6.2	-1.0	-0.8	2.0	2.5	-1.8	-1.4	-0.5	-1.8	0.9	-2.0	-1.1	-2.0	-1.5	-0.0	-0.8	-0.8	1.4
Exposure to tobacco smoke outside home	0.9	1.2	5.4	0.6	0.4	-2.3	-2.1	-0.3	-1.0	-0.1	-0.5	-0.9	-1.3	-0.6	-0.2	-0.5	-1.2	-0.6	-0.6	-1.7
Neck or shoulder pain in last month	0.9	1.3	4.8	0.5	-0.7	-0.2	-0.9	-0.8	-1.3	-2.2	-0.8	-0.5	-1.3	-1.1	-1.0	-0.9	-1.1	-1.5	-1.1	1.7
Medication: Omeprazole	0.9	1.0	3.4	-1.2	0.3	1.0	0.5	0.3	0.6	1.0	1.8	1.7	1.1	0.7	0.7	1.0	1.5	0.7	0.1	-1.0
Hypertension (Self-reported)	0.9	2.4	8.7	2.8	1.1	-1.0	-1.7	2.1	1.5	-0.2	0.1	-3.0	0.6	1.4	1.4	1.3	-1.3	0.6	1.7	-1.2
Vascular/heart problems diagnosed by doctor	0.9	2.3	11.1	-3.0	-0.8	1.2	1.6	-1.9	-1.2	1.3	0.5	3.3	0.2	-0.9	-0.9	-1.0	1.8	-0.1	-1.4	0.3
Worry (Nagel 2018)	0.8	1.6	6.7	2.6	1.2	-1.3	0.1	1.3	0.2	-1.0	0.4	-1.9	-1.4	0.2	0.1	0.4	-1.4	-0.3	0.5	2.6
Age at First Birth	0.8	1.1	7.1	-0.7	-0.5	1.4	1.4	0.0	0.0	0.3	0.5	0.9	2.7	-0.2	0.4	-0.2	0.8	0.1	-0.5	2.3
Blood Eosinophil Count	0.8	5.8	33.8	5.8	-0.1	-2.9	-0.4	1.4	0.5	-1.3	-1.7	-5.1	-2.4	-0.2	-0.0	-0.2	-3.7	-1.2	1.0	1.1
Hearing difficulty/problems: Yes	0.8	1.2	5.6	2.4	-1.0	-0.7	-0.1	0.9	0.7	-1.2	-1.1	-2.2	-0.3	0.2	0.3	-0.1	-1.3	-0.3	0.5	1.7
Alcohol usually taken with meals	0.8	1.3	4.6	1.6	-0.3	-2.1	-1.3	-0.1	0.0	-1.1	-0.2	-2.1	-1.6	-0.5	-0.2	-0.1	-2.0	-0.4	0.1	0.2
Hair/balding pattern: Pattern 2	0.8	1.0	3.8	1.9	-0.6	-0.8	-0.6	0.0	-0.5	-0.7	-0.4	-1.6	-1.0	-0.7	-0.5	-0.6	-1.7	-0.7	-0.3	1.8
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.6	1.9	-0.3	-1.5	-0.4	1.0	0.9	-1.5	0.3	-1.5	-1.3	0.7	1.0	0.8	-0.6	0.0	0.4	0.5
Weight	0.8	3.9	16.9	-0.1	1.6	1.0	1.3	1.5	2.0	3.1	1.5	0.0	0.6	2.2	2.2	2.1	1.5	2.2	2.1	-4.1
Falls in the last year	0.8	1.0	4.7	-2.2	0.8	1.1	0.3	-0.2	-0.3	1.1	1.2	2.2	0.4	0.2	0.5	0.3	1.4	0.7	-0.4	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.9	-1.4	-0.8	-0.8	-0.5	-1.2	-1.2	-1.0	-0.4	1.0	0.9	-1.2	-1.0	-1.0	-0.0	-0.9	-1.3	-0.1
Age at first live birth	0.8	1.4	12.1	1.7	-1.0	-0.3	1.0	0.7	0.2	-0.4	-0.6	-1.7	0.8	-0.2	-0.2	-0.4	-1.4	-0.3	0.3	3.5
Migraine (self-reported)	0.8	0.9	4.9	2.2	0.0	0.2	0.8	1.3	1.0	0.4	-0.4	-2.0	-0.3	0.7	0.2	0.4	-1.0	0.1	1.2	0.5
Heart disease (mother)	0.8	1.0	3.7	1.2	0.2	-0.9	-1.1	1.0	1.0	-0.1	-0.5	-1.9	-0.5	0.9	1.1	0.5	-0.9	0.4	1.0	-1.8
Eye problems/disorders: Cataract	0.8	1.0	2.8	0.4	-0.9	-1.7	-1.7	-1.0	-0.9	-1.3	-0.4	-0.9	-0.6	-0.9	-0.5	-0.7	-1.2	-0.9	-1.0	-0.6
Guilty feelings	0.8	1.2	3.1	-0.0	1.8	0.9	0.0	1.4	0.6	1.3	1.2	0.7	1.4	1.1	1.3	0.9	1.2	1.1	0.9	0.9
Medication: Lisinopril	0.8	1.0	2.8	-0.6	0.9	0.2	0.1	0.7	0.6	1.4	1.5	1.1	1.7	0.8	1.0	1.1	1.4	0.8	0.5	-1.0
Irritability	0.8	1.4	6.8	1.7	1.1	0.7	0.5	1.8	0.9	-0.1	1.1	-0.7	0.6	1.1	1.5	1.1	0.2	0.7	0.8	2.6
Cholesterol lowering medication	0.8	1.2	5.6	-0.5	-0.3	0.7	0.5	-0.9	-1.4	-2.0	-0.9	0.4	-0.6	-0.9	-1.3	-0.7	-0.0	-1.0	-1.2	2.4
Neuroticism (Nagel 2018)	0.7	1.8	17.1	1.8	1.7	-0.7	-0.4	1.3	-0.2	-0.8	0.8	-1.2	-0.7	0.2	0.2	0.4	-0.8	-0.3	0.1	4.1
Serious illness, injury or assault to yourself	0.7	0.8	2.6	0.9	-0.4	-0.3	1.6	1.3	1.6	0.5	0.2	-0.9	-0.2	1.1	0.9	0.8	-0.2	0.4	1.1	1.1
Hearing difficulty/problems with background noise	0.7	1.0	4.3	2.0	-0.2	-0.6	-0.5	1.1	0.6	-1.1	-0.7	-1.8	-0.3	0.3	0.5	0.1	-1.1	-0.0	0.8	2.1
Forced vital capacity (FVC)	0.7	2.6	11.3	-3.4	0.5	2.7	2.0	-1.5	-1.1	1.1	0.3	3.0	0.8	-0.5	-1.2	-0.3	2.1	0.5	-0.7	0.4
Happiness	0.7	0.9	2.8	1.6	-0.5	-1.4	-0.8	0.0	-0.2	-1.1	-0.8	-1.7	-0.6	-0.3	-0.1	-0.3	-1.6	-0.8	-0.2	1.0
Noisy workplace	0.7	0.8	2.8	1.3	-0.5	-1.7	-1.6	0.2	0.0	-0.3	-0.3	-1.4	-0.4	-0.2	0.3	0.0	-1.4	-0.7	-0.1	-1.4
Medication: Cholesterol lowering	0.7	1.1	5.1	2.1	0.3	-0.6	0.0	0.9	0.5	-1.0	0.0	-1.9	-1.2	0.2	-0.1	0.5	-1.0	-0.3	0.8	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	4.8	-1.3	-0.6	2.2	1.9	-1.8	-1.6	-0.7	-1.9	0.8	-2.1	-1.3	-2.2	-1.6	0.2	-0.6	-0.9	2.0
Exposure to tobacco smoke at home	0.7	0.8	3.0	1.7	-1.2	-1.2	-0.6	0.6	0.9	-0.5	-0.3	-1.7	-1.0	0.3	0.6	0.2	-1.0	0.1	0.7	0.4
Mouth/teeth dental problems: Bleeding gums	0.7	1.0	2.7	0.5	0.4	0.9	1.4	1.1	1.0	1.6	1.2	0.7	-0.4	1.0	0.9	0.9	1.4	1.0	0.9	0.0
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.6	1.1	0.2	-1.5	-1.6	0.3	-0.0	-0.4	-0.5	-1.4	-0.9	-0.2	-0.1	-0.1	-1.0	-0.4	0.3	-1.6
Leg fat-free mass (right)	0.7	3.9	10.4	-1.3	1.7	2.0	2.0	1.1	1.7	3.1	1.2	1.0	1.4	2.0	1.9	1.8	2.1	2.5	1.7	-3.2
Illnesses of father: None of the above (group 1)	0.7	0.9	2.7	-1.6	-0.0	-0.8	-0.8	-1.4	-1.0	-0.8	-0.8	0.8	0.1	-1.1	-1.0	-0.8	0.0	-0.9	-1.0	-1.5
Leg predicted mass (right)	0.7	3.8	10.4	-1.4	1.6	2.0	2.0	1.1	1.6	3.2	1.2	1.1	1.4	1.9	1.9	1.7	2.1	2.4	1.7	-3.2
Illnesses of father: High blood pressure	0.7	0.8	1.7	0.1	0.8	1.3	0.9	1.1	0.9	1.2	1.0	0.5	0.1	1.1	1.1	1.0	0.7	1.2	1.0	-0.2
Number of operations (self-reported)	0.7	1.0	3.5	-1.9	-0.5	-1.1	-1.4	-1.1	-0.9	-1.1	0.4	1.5	0.8	-0.8	-0.5	-0.6	0.6	-0.8	-1.3	-0.3
Leg fat mass (left)	0.7	2.8	7.6	0.7	1.3	0.3	0.8	1.8	2.0	2.5	1.7	-0.1	0.5	2.1	2.1	2.0	1.3	1.8	2.0	-2.8
Crohns Disease (2017)	0.6	1.2	2.5	-0.1	1.4	1.4	-0.5	1.4	0.7	1.6	1.1	0.7	0.7	1.2	1.0	1.3	1.0	1.4	1.2	-1.1
Neuroticism (2016)	0.6	0.8	3.8	-0.4	1.9	0.8	0.6	0.9	0.3	0.3	1.2	0.7	0.2	0.8	0.8	0.8	1.1	0.8	0.4	1.4
Smoking Status	0.6	1.5	3.2	-0.4	1.8	1.7	1.4	1.0	1.2	1.2	1.3	0.7	0.8	1.4	1.2	1.4	1.6	1.3	1.2	0.3
Neuroticism	0.6	1.4	10.2	1.9	1.5	-0.5	0.1	1.3	0.2	-1.2	0.5	-1.6	-0.2	0.5	0.5	0.6	-1.0	-0.1	0.3	3.2
Sitting height	0.6	4.4	16.5	1.9	-1.6	-2.3	-2.2	-0.4	0.0	-0.3	-3.0	-4.1	-2.0	-0.7	-0.9	-1.1	-3.4	-0.7	0.6	-3.7
Allergy	0.6	1.4	5.3	-1.6	1.3	2.3	1.1	0.1	-0.0	1.5	1.2	1.9	1.3	0.5	-0.2	0.4	1.7	0.9	0.4	0.1
Illnesses of siblings	0.6	0.8	2.1	-1.4	-0.5	0.4	-0.8	-1.2	-1.4	0.4	-0.5	1.4	-0.1	-1.1	-0.9	-1.0	0.3	-0.7	-1.3	0.0
Neuroticism score	0.6	1.3	5.8	2.2	1.0	-1.1	-0.7	1.0	-0.2	-1.0	-0.0	-1.9	-0.7	0.1	0.2	0.1	-1.4	-0.6	0.1	2.4
Number of live births	0.6	0.8	4.5	-0.8	-0.5	2.1	1.1	-0.2	0.3	1.3	0.1	1.3	-0.3	0.4	0.1	0.3	1.3	0.7	0.4	-0.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	6.3	-1.7	-0.1	2.5	2.3	-1.7	-1.5	0.1	-1.1	1.5	-1.2	-1.1	-2.1	-1.1	0.6	-0.3	-0.7	1.6
Glaucoma (self-reported)	0.6	0.7	2.8	1.7	-0.5	-0.0	0.4	1.1	1.5	0.0	0.1	-1.4	-0.1	0.8	0.9	0.6	-0.6	0.6	1.3	0.2
Leg fat percentage (right)	0.6	2.3	4.9	1.8	0.8	-0.5	0.2	1.9	1.9	1.8	1.6	-0.9	0.1	1.9	2.0	1.8	0.5	1.2	1.9	-2.2
Eye problems/disorders: None of the above	0.6	0.7	2.3	-0.8	1.5	0.8	-0.1	0.4	0.3	0.8	0.8	1.3	0.0	0.6	0.4	0.8	1.3	0.8	0.5	-0.7
Medication: Ibuprofen	0.6	0.7	4.1	0.7	1.0	2.0	1.6	0.5	0.2	0.2	-0.6	-0.5	-0.4	0.3	-0.0	0.2	-0.0	0.1	0.7	1.5
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	5.2	-2.3	0.5	1.1	-0.1	-0.8	-0.6	0.9	0.8	2.2	0.9	-0.3	-0.2	-0.1	1.5	0.1	-0.7	0.3
Osteoarthritis (self-reported)	0.6	0.8	3.7	-0.3	0.8	0.1	-0.7	0.9	0.6	0.5	1.9	0.7	1.0	0.7	0.9	1.0	0.8	0.6	0.4	1.4
Hearing aid user	0.6	0.7	4.0	1.1	-1.2	0.8	0.7	0.6	0.5	-0.5	-1.1	-0.8	1.0	0.2	0.2	-0.3	-0.5	-0.1	0.4	2.0
Financial situation satisfaction	0.6	0.7	2.3	-0.7	0.7	1.4	0.6	0.5	0.6	0.4	0.6	1.2	0.8	0.8	0.7	0.7	1.5	0.7	0.5	1.1
HDL Cholesterol	0.5	0.8	3.1	-0.2	0.2	0.5	0.2	0.3	-0.1	1.1	1.7	1.7	1.7	0.1	0.4	0.4	1.4	0.5	0.2	1.0
LDL Cholesterol	0.5	0.7	9.5	0.9	-0.2	0.5	1.1	0.2	-0.5	-0.4	-0.1	-0.2	-0.2	-0.1	-0.3	-0.2	0.2	-0.1	-0.1	3.1
Supplements: Zinc	0.5	0.5	1.8	-0.3	-0.0	1.3	0.3	0.5	0.7	0.4	0.9	0.8	1.4	0.7	0.7	0.7	0.7	0.6	0.1	-0.4
Current tobacco smoking	0.5	0.9	2.1	1.2	-1.2	-0.7	-0.7	-0.5	-0.3	-1.3	-1.1	-1.3	-1.4	-0.6	-0.7	-0.6	-1.2	-0.8	-0.4	0.3
Taking other prescription medications	0.5	0.8	2.6	1.6	0.7	-1.5	-1.2	1.2	0.7	-0.2	0.9	-1.0	0.1	0.6	0.8	0.9	-0.5	0.1	0.6	-0.9
Impedance of arm (right)	0.5	2.4	7.1	0.3	-2.7	-2.6	-1.5	-1.5	-0.8	-1.9	-1.1	-0.9	-1.9	-1.4	-1.7	-1.5	-1.5	-1.5	-1.2	-0.5
Medication: Paracetamol	0.5	0.8	2.2	1.0	0.9	0.8	0.5	1.2	1.0	0.4	0.3	-1.1	-0.6	1.1	0.7	1.0	-0.0	1.0	1.5	-0.4
Medication: Amlodipine	0.5	0.6	1.4	1.0	1.2	0.2	-0.2	1.1	0.8	1.0	1.0	-0.6	0.1	0.8	0.5	1.1	-0.4	0.6	1.0	-0.6
Number of full brothers	0.5	0.6	1.8	0.5	-0.7	1.4	1.1	0.6	0.6	0.4	0.6	0.6	-0.2	0.7	0.3	0.5	0.7	0.8	0.8	1.3
Medication for pain relief, constipation, heartburn	0.5	0.9	2.5	-1.5	-1.2	-0.6	-0.4	-1.1	-0.8	0.3	0.0	1.6	1.4	-0.9	-0.6	-0.9	0.4	-0.8	-1.3	-0.1
Suffer from ‘nerves’	0.5	0.9	3.7	1.9	0.9	-1.1	-0.2	0.9	0.5	-1.1	0.1	-1.9	-0.5	0.3	0.1	0.6	-1.2	-0.2	0.6	0.6
Leg pain on walking	0.5	0.6	4.7	0.0	-1.1	0.4	0.1	-0.6	-0.6	-0.7	-0.7	0.0	-0.3	-0.6	-0.8	-0.8	-0.4	-0.6	-0.5	2.2
Medication: Aspirin	0.5	0.6	3.2	1.7	-0.1	-0.8	0.0	0.5	0.4	-0.9	-0.6	-1.8	-0.8	0.1	0.0	0.1	-1.0	-0.3	0.5	0.4
Average weekly red wine intake	0.5	0.7	2.5	-1.0	-0.6	-1.6	-1.2	-1.0	-0.8	-0.5	-0.3	0.6	0.9	-1.0	-0.4	-0.8	0.0	-0.9	-1.1	0.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.4	0.8	-0.2	0.7	1.5	0.8	0.8	1.4	-0.1	-0.3	-1.0	0.7	0.5	0.2	-0.1	0.7	1.1	0.6
Qualifications: nursing, teaching	0.5	0.7	3.9	-1.5	0.2	0.2	0.9	0.3	0.9	0.9	0.7	0.7	2.0	0.7	0.9	0.4	0.8	0.9	0.1	-0.2
Back pain experienced in last month	0.5	0.8	3.5	1.6	0.7	0.4	-0.3	1.2	0.4	-0.8	-0.4	-1.6	0.1	0.5	0.5	0.3	-1.1	0.1	0.6	1.9
Medication: Aspirin	0.5	0.6	3.0	1.7	0.0	-1.2	-0.5	0.5	0.3	-0.7	-0.4	-1.6	-0.5	0.0	0.2	0.2	-1.0	-0.4	0.4	-0.3
Medication: Gliclazide	0.5	0.5	1.5	0.4	-0.6	-0.6	-0.4	-0.3	-0.8	-0.7	-1.2	-0.6	0.0	-0.7	-0.8	-1.2	-0.6	-1.1	-0.7	0.6
Ever taken oral contraceptive pill	0.5	0.6	1.8	0.4	0.4	1.1	0.5	1.1	1.4	0.5	-0.2	-0.2	0.8	1.0	0.8	0.6	0.4	0.8	1.2	0.3
Commuting to job workplace: Public transport	0.5	0.6	0.9	-0.8	0.9	0.9	0.8	0.5	0.8	0.8	0.8	0.5	0.8	0.9	0.6	0.9	0.9	0.9	0.6	-0.3
Leg fat percentage (left)	0.5	1.9	5.3	1.9	0.5	-0.9	-0.2	1.6	1.6	1.5	1.4	-1.0	0.0	1.5	1.7	1.6	0.2	1.0	1.6	-2.3
Depressed Affect (Nagel 2018)	0.4	0.9	8.8	0.0	1.8	-0.2	-0.5	0.5	-0.4	-0.7	1.0	-0.1	-0.1	0.1	0.4	0.4	0.1	-0.2	-0.3	3.0
Alzheimer’s Disease (in father)	0.4	0.4	1.2	-0.7	0.9	1.0	0.5	0.1	0.2	0.6	0.9	1.1	0.4	0.4	0.1	0.5	0.9	0.6	0.3	0.6
Medication: Co-codamol	0.4	0.5	1.2	-0.2	0.3	-1.0	-1.0	-0.6	-1.1	-0.3	0.2	0.1	-0.9	-0.8	-0.3	-0.5	-0.5	-0.9	-0.9	-0.7
Qualifications: CSEs or equivalent	0.4	0.6	4.6	-0.2	0.5	-0.3	-0.5	-0.5	-0.3	-1.1	-0.6	-0.3	-2.1	-0.2	-0.5	-0.2	-0.3	-0.3	-0.2	-1.3
Stomach or abdominal pain in last month	0.4	0.5	3.1	1.7	0.1	0.9	0.5	0.8	0.2	0.0	-0.1	-0.9	-0.1	0.3	0.2	0.3	-0.4	0.2	0.5	1.3
Number of incorrect matches in round	0.4	0.6	2.3	-1.0	1.3	-0.2	-1.5	-0.4	-0.6	-0.2	1.0	1.3	-0.4	-0.3	0.1	0.4	1.0	-0.0	-0.7	-0.1
Worrier / anxious feelings	0.4	0.8	3.0	0.3	0.4	-1.7	-0.2	-0.1	-1.0	-0.9	-0.2	-0.7	-0.8	-0.7	-0.6	-0.6	-1.1	-1.2	-0.9	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.1	0.3	-0.2	-1.1	-0.1	-0.4	-0.8	-1.4	-0.3	-0.5	-0.5	-0.7	-0.4	-0.7	-0.7	-1.2	-0.7	1.4
Hair/balding pattern: Pattern 4	0.4	1.0	4.6	-1.5	0.8	-0.1	0.1	-0.1	0.1	1.4	0.8	1.7	1.0	0.4	0.8	0.1	1.5	0.6	-0.1	-2.1
Forced vital capacity (FVC), Best measure	0.4	1.4	5.2	-2.3	0.1	2.2	1.5	-1.4	-1.0	0.2	-0.7	1.7	-0.3	-0.6	-1.2	-0.7	1.4	0.2	-0.6	0.6
Arm fat-free mass (right)	0.4	1.9	11.9	0.0	1.3	1.4	1.3	0.8	1.1	2.1	-0.2	-0.8	-0.5	1.3	1.0	1.1	0.4	1.5	1.5	-3.5
Number of children fathered	0.4	0.5	2.0	1.1	-0.2	-1.4	-1.1	0.1	-0.2	0.3	-0.5	-1.2	-0.0	-0.3	-0.1	-0.3	-0.9	-0.4	0.2	-0.5
Pulse wave peak to peak time	0.4	0.4	1.7	0.8	-1.3	-0.1	0.0	-0.3	-0.3	-0.2	-0.9	-0.8	-0.1	-0.5	-0.3	-0.8	-1.0	-0.6	-0.2	1.0
Medication: Seretide 50 evohaler	0.4	0.4	1.8	-0.1	0.2	0.8	0.3	0.4	0.5	0.4	0.8	0.7	1.3	0.6	0.8	0.8	0.8	0.3	0.3	-0.4
Arm predicted mass (right)	0.4	1.8	9.6	0.2	1.3	1.4	1.5	0.8	1.1	2.0	-0.1	-0.8	-0.5	1.3	1.1	1.2	0.4	1.4	1.5	-3.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.9	-1.1	0.2	-0.7	-1.7	-0.3	-0.4	-0.9	0.6	0.6	0.9	-0.1	-0.0	0.0	0.2	-0.0	-0.6	-0.9
Loneliness, isolation	0.4	0.6	5.1	0.9	1.2	0.2	-0.2	0.8	0.0	-0.6	0.5	-0.4	-0.6	0.4	0.5	0.5	0.1	-0.0	0.2	2.3
Long-standing illness, disability or infirmity	0.4	0.7	2.2	1.4	-0.6	-1.3	0.2	-0.0	-0.1	-1.0	-0.6	-1.5	-0.7	-0.3	-0.5	-0.3	-1.4	-0.9	-0.1	0.3
Medication for cholesterol	0.4	0.6	2.5	-1.3	-0.6	-0.1	0.3	-1.0	-0.7	0.9	0.1	1.6	-0.2	-0.8	-0.7	-0.9	0.7	-0.3	-0.8	0.5
Wears glasses or contact lenses	0.4	0.5	2.7	1.3	-1.2	0.3	0.3	0.2	0.2	-0.4	-0.3	-1.1	0.1	-0.1	-0.2	-0.1	-0.9	-0.3	0.3	1.7
Eye problems/disorders: Glaucoma	0.4	0.4	1.4	1.1	-0.1	-0.6	-0.1	0.8	1.0	-0.2	0.2	-1.2	0.1	0.5	0.8	0.4	-0.7	0.3	0.6	-0.7
Medication: Blood pressure	0.4	0.7	3.9	1.6	0.3	-0.2	-0.5	0.9	0.5	-0.5	-0.5	-2.0	0.6	0.7	0.7	0.6	-1.1	0.1	0.6	-1.0
Ever smoked	0.4	0.8	2.2	-0.6	1.5	0.8	0.2	0.6	0.6	1.3	1.4	0.8	0.7	0.7	1.0	1.0	1.2	0.8	0.5	0.2
Basal metabolic rate	0.4	2.3	13.0	-0.5	1.2	1.3	1.5	0.7	1.3	2.5	0.2	-0.2	0.0	1.5	1.3	1.2	0.9	1.7	1.5	-3.6
Average weekly beer plus cider intake	0.4	0.6	3.6	0.7	-0.2	0.7	1.6	0.7	0.4	1.9	0.2	-0.1	0.7	0.4	0.3	0.3	0.1	0.6	0.8	-0.1
Commuting to job workplace: Cycle	0.4	0.5	2.5	0.2	-0.8	-0.1	0.1	-0.7	-0.9	-0.6	-0.7	-0.1	0.1	-1.0	-0.7	-0.8	-0.5	-0.7	-0.8	1.6
Basal cell carcinoma (self-reported)	0.4	0.5	1.5	-0.2	0.6	0.3	-0.2	0.8	0.4	0.9	0.7	1.1	1.2	0.3	0.8	0.3	0.9	0.7	0.4	1.0
Pack years of smoking	0.4	0.6	2.4	1.5	-0.9	-0.9	-1.1	0.5	0.4	-0.3	-0.3	-1.6	-0.1	0.3	0.8	0.5	-0.9	-0.1	0.4	-0.3
Arm predicted mass (left)	0.4	1.8	10.7	0.4	1.2	1.0	1.2	0.9	1.2	1.8	-0.2	-1.2	-0.6	1.4	1.0	1.2	0.1	1.3	1.6	-3.3
Irritable Bowel Disease (IBD)	0.3	0.7	3.5	0.1	1.9	0.8	-0.4	0.8	0.1	0.8	1.0	0.2	-0.1	0.8	0.4	1.1	0.6	1.0	0.9	-1.3
Crohns Disease (2012)	0.3	0.4	3.6	-0.5	-0.1	-0.3	-1.9	-0.3	-1.0	-0.7	-0.5	0.4	-0.5	-0.5	-0.6	-0.4	-0.0	-0.3	-0.4	-0.3
Mean Putamen Volume	0.3	0.3	1.8	-0.0	1.3	-0.2	0.3	0.5	0.3	0.3	0.8	0.0	1.0	0.4	0.8	0.6	0.3	0.3	0.1	-0.1
Blood Platelet Count	0.3	4.0	38.4	3.2	0.1	0.4	1.8	1.5	0.9	-2.4	-0.3	-2.1	-0.3	0.4	1.0	0.5	-1.1	-0.1	0.6	6.2
Respiratory disease	0.3	0.7	2.3	1.5	0.3	-0.3	-0.8	1.1	0.9	1.0	0.6	-0.9	0.1	0.7	1.1	0.9	-0.3	0.5	1.0	-1.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.1	-1.3	-0.2	0.2	0.8	-0.1	0.4	-0.4	0.3	0.9	1.5	0.3	0.4	0.2	0.7	-0.2	-0.2	-0.5
Pack years adult smoking proportion	0.3	0.4	1.8	1.4	-0.9	-0.6	-0.8	0.4	0.2	-0.3	-0.3	-1.2	0.0	0.2	0.7	0.3	-0.7	-0.1	0.3	0.2
Waist circumference	0.3	1.2	7.7	0.9	0.4	0.0	0.6	0.9	1.3	1.2	0.3	-1.1	-0.6	1.2	1.2	1.1	0.0	0.8	1.3	-2.8
Hair/balding pattern: Pattern 3	0.3	0.5	1.4	-1.0	-0.2	-0.9	-0.8	-0.4	-0.5	-1.2	0.1	0.5	1.0	-0.5	-0.6	-0.3	0.0	-0.6	-0.8	0.7
Pulse wave Arterial Stiffness index	0.3	0.4	1.5	-0.7	1.2	-0.2	-0.2	0.1	0.2	0.0	0.7	0.6	-0.4	0.4	0.1	0.7	0.8	0.5	0.2	-1.2
Impedance of arm (left)	0.3	1.4	5.8	0.1	-2.4	-1.9	-1.1	-1.2	-0.6	-1.1	-0.9	-0.4	-1.3	-1.1	-1.4	-1.3	-1.1	-1.1	-0.9	-0.4
Blood clot in the leg (DVT)	0.3	0.4	1.0	0.3	-0.6	-0.8	-0.7	-0.4	-0.6	-0.4	-0.5	-0.6	-1.0	-0.7	-0.6	-0.6	-0.8	-0.8	-0.6	0.4
Worry too long after embarrassment	0.3	0.5	4.9	1.3	-0.0	0.2	-0.0	0.8	-0.2	0.3	-0.3	-1.0	0.2	0.0	0.0	-0.2	-0.8	-0.2	0.2	2.2
Wheeze or whistling in the chest in last year	0.3	0.5	3.3	1.8	-0.1	0.2	0.2	1.0	0.7	0.7	0.3	-0.8	0.3	0.7	0.9	0.8	-0.3	0.4	0.8	0.6
Shortness of breath walking on level ground	0.3	0.4	1.8	0.1	-1.3	0.6	1.1	-0.2	-0.3	0.1	-0.5	0.1	0.6	-0.3	-0.5	-0.7	0.2	-0.4	-0.2	1.4
Mouth/teeth dental problems: Loose teeth	0.3	0.3	3.0	0.3	-0.2	0.3	0.1	-0.4	-0.7	-0.4	0.1	0.2	-0.2	-0.5	-0.6	-0.3	-0.1	-0.6	-0.6	1.7
Medication: Allopurinol	0.3	0.4	1.6	1.2	0.2	-1.0	-1.2	0.3	-0.1	0.5	-0.4	-0.8	-0.4	-0.1	-0.5	-0.1	-0.9	-0.3	0.4	-0.3
Age at last live birth	0.3	0.5	4.7	1.1	-0.2	0.2	0.6	0.5	0.1	-0.2	-0.5	-1.0	0.2	-0.0	-0.1	-0.1	-0.7	0.1	0.5	2.2
Family relationship satisfaction	0.3	0.3	1.4	-0.3	-0.4	-0.1	0.6	-0.2	-0.0	-1.2	-0.9	-0.4	0.9	0.0	-0.2	-0.3	-0.2	-0.5	-0.3	1.2
Illnesses of father: Heart disease	0.3	0.4	1.3	1.1	-1.1	-0.6	-0.4	0.7	0.4	0.0	0.6	-0.9	0.4	0.5	0.1	0.5	-0.5	0.0	0.3	0.6
Whole body fat-free mass	0.3	1.7	10.6	-0.7	1.1	1.3	1.4	0.4	1.0	2.1	-0.2	-0.2	-0.1	1.1	1.0	0.9	0.7	1.4	1.2	-3.2
Asthma (self-reported)	0.3	0.5	3.4	1.9	-0.4	-1.0	-0.8	0.8	0.2	0.6	0.1	-0.9	-0.0	0.1	0.5	0.3	-0.7	-0.1	0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	4.6	0.1	0.1	1.4	1.0	-0.3	-0.8	-0.3	-0.6	0.4	-0.3	-0.6	-1.0	-0.6	0.3	-0.0	-0.1	2.1
Whole body water mass	0.3	1.7	10.5	-0.7	1.1	1.3	1.4	0.4	0.9	2.1	-0.2	-0.2	-0.1	1.1	1.0	0.9	0.7	1.4	1.2	-3.2
Miserableness	0.3	0.5	3.5	-0.3	1.5	0.2	-0.4	0.2	-0.7	-0.4	0.8	0.5	0.2	-0.1	0.0	0.2	0.3	-0.3	-0.3	1.9
Medication: Paracetamol	0.3	0.4	1.1	0.6	1.0	0.9	-0.3	0.6	0.5	-0.1	0.4	-0.8	-0.8	0.6	0.2	0.8	-0.3	0.5	1.1	-0.3
Arm fat-free mass (left)	0.3	1.6	11.7	0.0	1.2	0.9	1.0	0.6	0.9	1.8	-0.1	-0.9	-0.5	1.1	0.9	1.1	0.2	1.2	1.3	-3.4
Risk taking	0.3	0.4	2.8	-0.0	0.2	0.8	0.2	0.6	0.7	0.6	-0.5	-0.4	1.7	0.5	0.8	0.1	0.2	0.5	0.4	-0.8
Fractured/broken bones in last 5 years	0.3	0.4	2.5	-0.4	-0.2	-0.6	0.5	0.2	0.3	1.6	0.5	0.4	-0.3	0.3	0.4	0.1	0.3	0.1	0.4	-1.4
Ulcerative Colitis (UC)	0.2	0.4	2.3	0.2	1.5	0.3	0.3	0.0	-0.2	0.1	0.4	-0.3	-0.9	0.3	-0.1	0.5	0.0	0.4	0.6	-1.4
Rheumatoid Arthritis	0.2	0.3	1.0	0.9	0.6	-0.3	0.5	0.8	0.1	1.0	-0.0	-0.2	-0.7	0.2	0.1	0.1	0.1	0.2	0.6	-0.9
Ulcerative Colitis	0.2	0.3	1.1	-0.2	0.7	-0.3	-0.8	-0.4	-1.0	-0.4	0.5	0.7	-0.2	-0.4	-0.1	-0.2	0.5	-0.0	-0.5	0.6
Chronotype (morning person)	0.2	0.5	1.9	0.4	-0.4	1.3	1.4	0.9	1.2	-0.1	0.6	-0.1	-0.1	0.8	0.3	0.7	0.5	0.4	0.9	0.3
Hair Pigment	0.2	6.9	24.7	-1.5	0.7	4.5	4.0	1.4	1.9	0.3	2.2	2.6	3.0	2.1	1.7	1.7	3.2	2.4	1.2	5.0
Tanning	0.2	2.2	15.4	-1.9	0.9	-1.9	-2.3	-1.3	-1.3	0.5	0.5	1.3	-0.1	-1.0	-0.5	-0.4	0.2	-0.8	-1.1	-3.9
Relative age of first facial hair	0.2	0.4	1.5	-0.5	-0.1	1.2	0.5	0.1	0.6	0.7	0.3	0.4	0.7	0.4	0.5	0.6	0.5	0.4	0.4	-1.1
Diabetes (father)	0.2	0.3	1.5	1.2	0.6	0.1	-0.0	0.4	0.2	1.0	0.3	-0.4	-1.2	0.2	0.3	0.3	-0.2	0.1	0.5	0.4
Severe depression (siblings)	0.2	0.2	0.9	-0.5	0.7	0.4	-0.1	0.3	0.2	-0.3	0.4	0.4	1.0	0.4	0.6	0.4	0.3	0.6	0.2	0.2
Hand grip strength (right)	0.2	0.5	1.5	-1.2	0.3	-0.4	-0.6	-0.9	-1.2	-0.6	-0.5	0.3	0.5	-0.9	-0.9	-0.7	-0.1	-0.3	-0.8	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.7	-0.6	1.0	1.3	0.7	0.3	0.2	0.9	0.8	1.1	0.8	0.4	0.3	0.5	1.1	0.6	0.5	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.9	-0.7	0.1	-0.9	-0.1	-0.5	-0.5	-0.4	0.2	0.9	-0.1	-0.4	-0.3	-0.4	0.4	-0.3	-0.4	0.0
Mouth/teeth dental problems	0.2	0.3	1.7	0.3	-0.4	0.1	0.3	0.7	1.0	0.0	0.0	-0.3	1.3	0.5	0.6	0.3	-0.1	0.5	0.7	0.7
Medication: Simvastatin	0.2	0.3	1.6	-0.3	0.2	0.6	0.2	0.4	0.3	-0.4	0.9	0.7	0.6	0.3	0.2	0.7	0.8	0.5	0.3	1.3
Trunk fat-free mass	0.2	0.9	8.5	-0.3	0.4	0.8	0.9	-0.2	0.3	1.2	-1.2	-1.0	-0.9	0.4	0.2	0.2	-0.3	0.6	0.7	-2.9
Qualifications: A levels/AS levels or equivalent	0.2	0.5	3.3	-0.6	0.5	0.4	1.1	0.3	0.6	0.4	0.6	0.4	1.8	0.2	0.5	0.2	0.3	0.5	0.0	1.0
Asthma	0.2	0.5	3.0	1.7	-0.2	-0.9	-0.7	0.7	0.1	0.6	0.1	-0.9	-0.0	0.1	0.5	0.3	-0.7	-0.1	0.4	-0.8
Trunk predicted mass	0.2	1.0	8.5	-0.4	0.5	0.9	1.0	-0.2	0.3	1.3	-1.2	-0.9	-0.8	0.4	0.2	0.2	-0.2	0.6	0.7	-2.9
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.9	-0.0	-0.9	-0.7	-0.3	-0.5	-0.4	-0.2	-0.3	0.1	-0.5	-0.6	-0.7	-0.7	-0.7	-0.7	-0.6	0.3
Gout (self-reported)	0.2	0.2	1.3	0.4	0.1	-0.4	-0.6	-0.2	-0.7	0.0	-0.5	-0.1	-0.6	-0.5	-1.1	-0.4	-0.4	-0.6	0.0	-0.0
Birth weight	0.2	0.4	1.8	-0.5	-1.4	-0.5	-0.2	-0.8	-0.5	0.1	0.1	0.2	-0.1	-0.8	-0.5	-0.5	-0.4	-0.4	-0.7	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	1.1	0.3	0.4	-0.3	0.4	0.5	0.4	0.3	0.8	0.3	1.1	0.4	0.6	0.3	0.3	0.3	0.2	0.7
Emphysema/chronic bronchitis	0.2	0.2	0.7	0.2	-0.9	0.7	-0.2	0.1	0.1	0.9	0.0	0.4	-0.6	-0.1	-0.1	-0.2	0.1	0.2	0.3	0.8
Mood swings	0.2	0.4	2.0	-0.5	1.4	-0.5	-1.0	0.3	-0.5	-0.1	0.8	0.4	0.4	-0.0	0.3	0.3	0.1	-0.3	-0.4	1.2
Smoking status: Current	0.2	0.4	2.1	1.5	-0.5	-0.1	-0.1	0.1	0.4	-0.6	-0.4	-1.3	-0.8	0.1	-0.0	0.1	-0.7	-0.1	0.3	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.8	-0.3	0.7	0.2	0.1	0.3	-0.0	-1.0	0.7	0.3	0.1	0.1	0.1	0.4	0.4	0.2	-0.1	1.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.0	0.0	-0.2	-1.0	-1.0	-0.1	-0.3	0.6	-0.1	-0.1	0.8	-0.4	0.1	-0.4	-0.4	-0.2	-0.4	-0.6
Primary Biliary Cirrhosis	0.1	0.1	0.8	0.5	0.1	-0.0	0.8	0.1	0.4	0.1	0.1	-0.1	-0.7	0.1	0.2	0.1	0.1	0.1	0.3	0.9
Hand grip strength (left)	0.1	0.2	0.7	-0.1	0.3	0.5	0.6	-0.1	-0.4	0.3	-0.8	-0.3	0.2	-0.3	-0.5	-0.4	-0.2	0.2	0.2	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.6	0.3	0.6	0.7	0.8	0.3	0.3	0.4	0.4	-0.0	0.3	0.4	0.3	0.3	0.3	0.3	0.4	-0.4
Had menopause	0.1	0.2	0.4	-0.3	0.6	0.4	-0.4	0.2	0.5	-0.3	0.5	0.0	0.1	0.6	0.4	0.5	0.3	0.5	0.3	-0.1
Father’s age at death	0.1	0.1	0.5	-0.5	-0.2	0.2	0.5	0.0	0.4	0.1	-0.2	0.4	0.7	0.1	0.7	-0.1	0.3	0.1	-0.1	-0.3
Breastfed as a baby	0.1	0.1	0.9	0.2	0.4	0.4	-0.0	-0.1	-0.1	-0.4	-0.2	-0.1	-0.9	-0.0	0.0	0.0	-0.3	0.1	0.0	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.5	0.5	-0.5	-0.1	-0.4	-0.1	-0.2	0.7	0.7	0.1	0.2	-0.2	0.0	0.3	-0.2	-0.2	-0.0	-0.5
Chronic bronchitis/emphysema (mother)	0.1	0.2	1.2	-0.2	-0.3	-0.5	-1.1	0.2	-0.0	0.1	0.7	0.5	0.4	0.0	0.2	0.2	0.1	-0.2	-0.1	-0.3
Chest pain or discomfort	0.1	0.2	1.0	-0.4	0.3	1.0	0.3	-0.4	-0.3	-0.6	0.4	0.7	0.7	-0.1	-0.1	0.3	0.4	0.3	-0.3	0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.7	0.5	-0.4	-0.6	-0.5	-0.0	-0.2	-0.1	-0.2	-0.6	-0.9	-0.3	-0.3	-0.3	-0.5	-0.4	-0.2	-0.0

Hub : Genes

DRG2

Models

Trait associations