TWAS
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Models
Genes
Traits
Hub
:
Genes
MRPL33
Models
#
panel
tissue
h2
h2 se
h2 P
eQTL R2
BLUP R2
ENET R2
BSLMM R2
LASSO R2
eQTL P
BLUP P
ENET P
BSLMM P
LASSO P
1
YFS
Blood
0.0244
0.0109
3.8e-05
0.007
0.012
0.007
0.01
0.005
0.0014
6.4e-05
0.0017
0.00024
0.007
Trait associations
Trait
Avg chi2 ratio
Avg chi2
Max chi2
1
Trait
Avg chi2 ratio
Avg chi2
Max chi2
1
Triglycerides
28.6
46.8
46.8
6.8
Fasting Glucose
15.7
18.8
18.8
-4.3
Impedance of arm (left)
11.4
52.7
52.7
7.3
Major Depression (MDD)
10.9
13.2
13.2
3.6
Had menopause
10.1
12.6
12.6
3.5
Impedance of arm (right)
9.9
46.2
46.2
6.8
Impedance of whole body
9.5
48.6
48.6
7.0
Worry too long after embarrassment
7.0
11.7
11.7
-3.4
Alcohol intake frequency.
7.0
16.2
16.2
4.0
Bipolar Disorder or Schizophrenia
6.7
16.2
16.2
4.0
Trunk fat-free mass
6.7
38.6
38.6
-6.2
Medication: Allopurinol
6.6
8.8
8.8
3.0
Trunk predicted mass
6.4
36.6
36.6
-6.0
Arm predicted mass (right)
6.4
32.8
32.8
-5.7
Alcohol drinker status: Previous
6.4
7.3
7.3
2.7
Whole body water mass
6.1
34.6
34.6
-5.9
Qualifications: O levels/GCSEs or equivalent
6.0
9.5
9.5
-3.1
Whole body fat-free mass
6.0
34.1
34.1
-5.8
Impedance of leg (right)
5.9
28.6
28.6
5.3
Number of incorrect matches in round
5.9
9.9
9.9
3.1
Arm fat-free mass (right)
5.9
30.0
30.0
-5.5
Prostate Cancer
5.8
8.2
8.2
2.9
Arm predicted mass (left)
5.8
29.5
29.5
-5.4
Guilty feelings
5.7
8.5
8.5
-2.9
Ever unenthusiastic/disinterested for a whole week
5.6
6.8
6.8
2.6
Smoking status: Previous
5.6
8.4
8.4
2.9
Average weekly champagne plus white wine intake
5.5
7.5
7.5
-2.7
Arm fat-free mass (left)
5.4
27.5
27.5
-5.2
Basal cell carcinoma (self-reported)
5.4
6.5
6.5
-2.5
Impedance of leg (left)
5.3
25.8
25.8
5.1
Schizophrenia (2014)
5.2
11.5
11.5
3.4
Medication: Cholesterol lowering
5.2
8.1
8.1
2.9
Bipolar Disorder (2011)
5.1
4.9
4.9
2.2
Illnesses of siblings: Diabetes
5.1
6.3
6.3
-2.5
Basal metabolic rate
5.0
27.7
27.7
-5.3
Bipolar Disorder (2018)
4.9
7.7
7.7
2.8
Lung FEV1/FVC ratio
4.9
25.0
25.0
-5.0
Exposure to tobacco smoke outside home
4.9
6.6
6.6
-2.6
Leg predicted mass (right)
4.7
24.9
24.9
-5.0
Leg fat-free mass (right)
4.6
24.5
24.5
-5.0
Blood Red Count
4.5
43.3
43.3
-6.6
Mouth/teeth dental problems: Dentures
4.5
7.5
7.5
-2.7
Other serious medical condition/disability diagnosed by doctor
4.4
5.7
5.7
2.4
Fluid intelligence score
4.4
9.1
9.1
-3.0
Schizophrenia (2018)
4.2
8.6
8.6
2.9
Primary Biliary Cirrhosis
4.2
5.9
5.9
2.4
Relative age of first facial hair
4.2
8.5
8.5
2.9
Pulse rate, automated reading
4.1
13.2
13.2
3.6
Leg fat-free mass (left)
4.0
21.3
21.3
-4.6
Leg predicted mass (left)
4.0
21.3
21.3
-4.6
Illnesses of father: None of the above (group 1)
3.8
4.7
4.7
-2.2
Ever depressed for a whole week
3.8
4.7
4.7
2.2
Age at First Birth
3.7
5.4
5.4
2.3
Blood Eosinophil Count
3.5
27.1
27.1
-5.2
Blood Platelet Count
3.5
40.6
40.6
6.4
Maternal smoking around birth
3.5
5.1
5.1
2.3
Past tobacco smoking
3.5
6.4
6.4
-2.5
Gout (self-reported)
3.5
4.8
4.8
2.2
Ever had bowel cancer screening
3.5
4.1
4.1
2.0
Ovarian Cancer
3.4
4.5
4.5
-2.1
Medication: Simvastatin
3.4
5.0
5.0
2.2
Worrier / anxious feelings
3.4
6.5
6.5
-2.5
Supplements: Calcium
3.4
3.7
3.7
1.9
High cholesterol (Self-reported)
3.2
5.7
5.7
2.4
LDL Cholesterol
3.1
4.9
4.9
2.2
Forced expiratory volume in 1-second (FEV1), Best measure
3.1
9.9
9.9
-3.1
Number of self-reported non-cancer illnesses
3.1
5.4
5.4
2.3
Irritability
3.1
5.3
5.3
-2.3
Crohns Disease (2017)
2.9
6.3
6.3
2.5
Neuroticism score
2.9
6.1
6.1
-2.5
Health satisfaction
2.9
3.8
3.8
2.0
Hearing difficulty/problems with background noise
2.8
4.5
4.5
2.1
Qualifications: A levels/AS levels or equivalent
2.8
6.2
6.2
-2.5
Peak expiratory flow (PEF)
2.8
6.6
6.6
-2.6
Mineral and other dietary supplements
2.8
3.7
3.7
-1.9
Pulse wave reflection index
2.5
3.1
3.1
-1.8
Deep venous thrombosis (DVT) (self-reported)
2.5
3.3
3.3
1.8
Worry (Nagel 2018)
2.4
5.1
5.1
-2.3
Neuroticism (2016)
2.4
3.4
3.4
-1.9
Loud music exposure frequency
2.4
2.6
2.6
1.6
Blood clot in the leg (DVT)
2.4
3.1
3.1
1.8
Ever smoked
2.4
4.2
4.2
2.0
Neuroticism
2.3
5.6
5.6
-2.4
Average weekly spirits intake
2.3
2.9
2.9
1.7
Blood White Count
2.2
16.0
16.0
4.0
Suffer from ‘nerves’
2.2
3.5
3.5
-1.9
Medication for pain relief, constipation, heartburn
2.1
3.6
3.6
1.9
Neuroticism (Nagel 2018)
2.0
4.7
4.7
-2.2
Body Mass Index (BMI) (2010)
2.0
2.8
2.8
1.7
Mother’s age at death
2.0
2.5
2.5
1.6
Smoking Status
1.9
4.5
4.5
2.1
Chronotype (morning person)
1.9
4.5
4.5
-2.1
Sensitivity / hurt feelings
1.9
3.3
3.3
-1.8
Forced expiratory volume in 1-second (FEV1)
1.9
6.3
6.3
-2.5
Age when periods started (menarche)
1.8
4.3
4.3
2.1
Age at first live birth
1.8
3.2
3.2
-1.8
Intelligence (Savage-Jansen 2018)
1.7
5.3
5.3
-2.3
Qualifications: None of the above
1.7
3.6
3.6
1.9
Medication for cholesterol, blood pressure or diabetes
1.7
2.8
2.8
-1.7
Number of children fathered
1.7
1.9
1.9
-1.4
Commuting to job workplace: Cycle
1.7
2.0
2.0
-1.4
High blood pressure
1.6
4.4
4.4
2.1
Weight
1.6
7.8
7.8
-2.8
Pulse rate
1.6
2.6
2.6
1.6
Number of full brothers
1.6
2.0
2.0
1.4
Eye problems/disorders: Cataract
1.6
1.9
1.9
-1.4
Medication for cholesterol
1.6
2.4
2.4
-1.5
Verbal and Numeric Reasoning (VNR)
1.5
3.6
3.6
-1.9
Sitting height
1.5
10.8
10.8
-3.3
Mood swings
1.5
2.7
2.7
-1.6
Asthma (self-reported)
1.5
3.0
3.0
1.7
Supplements: Fish oil (including cod liver oil)
1.5
1.9
1.9
1.4
Ever had prostate specific antigen (PSA) test
1.5
1.8
1.8
-1.3
Depression (Nagel 2018)
1.3
2.0
2.0
1.4
Coronary Artery Disease (CAD)
1.3
1.6
1.6
1.3
Asthma
1.3
2.6
2.6
1.6
Headache pain in last month
1.3
2.2
2.2
-1.5
Ever taken oral contraceptive pill
1.3
1.4
1.4
-1.2
Diabetes (mother)
1.2
1.6
1.6
-1.3
Supplements: Glucosamine
1.2
1.5
1.5
1.2
Chronic bronchitis/emphysema (father)
1.2
1.4
1.4
1.2
Length of working week for main job
1.2
1.3
1.3
-1.1
Exposure to tobacco smoke at home
1.2
1.3
1.3
-1.1
Hearing aid user
1.2
1.4
1.4
1.2
Medication: Blood pressure
1.2
2.2
2.2
1.5
Vascular/heart problems diagnosed by doctor
1.2
3.3
3.3
-1.8
Cardiovascular Disease
1.1
3.7
3.7
1.9
Fed-up feelings
1.1
2.0
2.0
-1.4
Hip circumference
1.1
4.8
4.8
-2.2
Seen a psychiatrist for nerves, anxiety, tension or depression
1.1
1.5
1.5
1.2
Comparative height size at age 10
1.1
6.0
6.0
-2.4
Friendships satisfaction
1.1
1.4
1.4
1.2
Crohns Disease (2012)
1.0
1.6
1.6
1.3
Lung FVC
1.0
5.2
5.2
2.3
Hearing difficulty/problems: Yes
1.0
1.6
1.6
1.3
Trunk fat percentage
1.0
4.1
4.1
2.0
Body mass index (BMI)
1.0
4.2
4.2
-2.0
Heart attack
1.0
1.2
1.2
-1.1
Alcohol intake versus 10 years previously
1.0
1.5
1.5
1.2
Birth weight of first child
1.0
1.8
1.8
-1.3
Qualifications: nursing, teaching
1.0
1.6
1.6
-1.2
Alcohol drinker status: Never
1.0
1.1
1.1
1.1
Irritable Bowel Disease (IBD)
0.9
2.1
2.1
1.4
Diabetes (father)
0.9
1.1
1.1
-1.0
Comparative body size at age 10
0.9
2.5
2.5
-1.6
Medication: Omeprazole
0.9
1.0
1.0
-1.0
Illnesses of father: Heart disease
0.9
1.3
1.3
1.1
Forced expiratory volume in 1-second (FEV1), predicted
0.9
1.8
1.8
-1.3
Medication: Omeprazole (e.g. Zanprol)
0.9
1.1
1.1
-1.0
Respiratory disease
0.8
1.8
1.8
1.3
Medication: Atenolol
0.8
0.9
0.9
-1.0
Alcohol usually taken with meals
0.8
1.3
1.3
1.1
Noisy workplace
0.8
0.9
0.9
1.0
Depression (self-reported)
0.8
0.9
0.9
-1.0
Hair/balding pattern: Pattern 4
0.8
2.0
2.0
1.4
Qualifications: College or University degree
0.8
2.6
2.6
-1.6
Commuting to job workplace: Car/motor vehicle
0.8
0.9
0.9
0.9
Medication: Gliclazide
0.8
0.9
0.9
0.9
Pack years adult smoking proportion
0.7
1.1
1.1
-1.0
Townsend deprivation index at recruitment
0.7
0.9
0.9
1.0
Nervous feelings
0.7
1.4
1.4
-1.2
Hair/balding pattern: Pattern 2
0.7
0.9
0.9
0.9
Had other major operations
0.7
0.8
0.8
-0.9
Illnesses of siblings
0.7
0.9
0.9
1.0
Mouth/teeth dental problems: Bleeding gums
0.7
0.9
0.9
0.9
Hypothyroidism/myxoedema (self-reported)
0.7
1.3
1.3
1.1
Body fat percentage
0.7
2.8
2.8
1.7
Angina (self-reported)
0.7
0.9
0.9
0.9
Had major operations
0.7
0.8
0.8
0.9
Hypertension (Self-reported)
0.7
2.0
2.0
1.4
Ever had stillbirth, spontaneous miscarriage or termination
0.7
0.8
0.8
-0.9
Back pain experienced in last month
0.7
1.0
1.0
-1.0
Pain type(s) experienced in last month: Hip pain
0.7
0.9
0.9
1.0
Rheumatoid Arthritis
0.6
0.9
0.9
0.9
Ever had hysterectomy (womb removed)
0.6
0.7
0.7
0.8
Heel bone mineral density (BMD) T-score, automated (right)
0.6
1.3
1.3
1.1
Forced vital capacity (FVC), Best measure
0.6
2.2
2.2
-1.5
Medication: Seretide 50 evohaler
0.6
0.7
0.7
0.8
Mouth/teeth dental problems: Mouth ulcers
0.6
1.0
1.0
1.0
Medication: Bendroflumethiazide
0.6
0.9
0.9
0.9
Fractured/broken bones in last 5 years
0.6
0.7
0.7
-0.8
Reaction Time
0.5
0.9
0.9
-1.0
HbA1C
0.5
0.6
0.6
-0.7
BMI
0.5
3.1
3.1
-1.8
Ever used hormone-replacement therapy (HRT)
0.5
0.7
0.7
0.8
Angina
0.5
0.6
0.6
0.8
Medication: Co-codamol
0.5
0.6
0.6
0.8
Bilateral oophorectomy (both ovaries removed)
0.5
0.5
0.5
-0.7
Waist circumference
0.5
1.7
1.7
-1.3
Frequency of tiredness / lethargy in last 2 weeks
0.5
0.8
0.8
-0.9
Hair/balding pattern: Pattern 3
0.5
0.8
0.8
-0.9
Breastfed as a baby
0.5
0.6
0.6
0.8
Seen doctor (GP) for nerves, anxiety, tension or depression
0.5
0.7
0.7
0.9
Medication: Paracetamol
0.5
0.9
0.9
-0.9
Qualifications: NVQ or HND or HNC or equivalent
0.5
0.5
0.5
0.7
Knee pain experienced in last month
0.5
0.8
0.8
0.9
Osteoarthritis (self-reported)
0.5
0.6
0.6
0.8
Unable to work because of sickness or disability
0.5
0.7
0.7
0.8
Cholesterol lowering medication
0.5
0.7
0.7
0.8
Heart attack/myocardial infarction (self-reported)
0.5
0.6
0.6
-0.8
Alzheimer’s Disease (including proxy)
0.4
0.6
0.6
0.8
Heel T-Score
0.4
3.4
3.4
1.9
Medication for hormone replacement therapy
0.4
0.5
0.5
0.7
Average weekly fortified wine intake
0.4
0.4
0.4
0.7
Taking other prescription medications
0.4
0.6
0.6
0.8
Allergy
0.4
0.8
0.8
-0.9
Medication: Ibuprofen (e.g. Nurofen)
0.4
0.5
0.5
-0.7
Shortness of breath walking on level ground
0.4
0.4
0.4
0.6
Long-standing illness, disability or infirmity
0.4
0.7
0.7
0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage
0.4
0.9
0.9
-1.0
Illnesses of father: High blood pressure
0.4
0.5
0.5
-0.7
Alzheimer’s Disease (in father)
0.3
0.3
0.3
0.6
Hayfever, allergic rhinitis or eczema
0.3
0.7
0.7
0.8
Time employed in main current job
0.3
0.4
0.4
0.6
Falls in the last year
0.3
0.4
0.4
0.6
Prospective memory result
0.3
0.4
0.4
0.6
Arm fat mass (right)
0.3
1.1
1.1
-1.0
Standing height
0.3
3.5
3.5
-1.9
Reason for reducing amount of alcohol drunk: Health precaution
0.3
0.3
0.3
0.6
Heart disease (mother)
0.3
0.3
0.3
-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)
0.3
0.3
0.3
0.6
Arm fat mass (left)
0.3
1.0
1.0
-1.0
Medication: Lisinopril
0.3
0.4
0.4
-0.6
Number of operations (self-reported)
0.3
0.4
0.4
0.6
Leg fat mass (left)
0.3
1.2
1.2
-1.1
Mean Putamen Volume
0.2
0.2
0.2
0.5
Height
0.2
3.2
3.2
-1.8
Eye problems/disorders: Diabetes related eye disease
0.2
0.2
0.2
-0.4
Vitamin and mineral supplements
0.2
0.3
0.3
-0.5
Severe depression (siblings)
0.2
0.2
0.2
0.4
Hand grip strength (right)
0.2
0.6
0.6
-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks
0.2
0.3
0.3
0.6
Diverticular disease/diverticulitis (self-reported)
0.2
0.2
0.2
-0.5
Arm fat percentage (right)
0.2
0.7
0.7
0.8
Leg fat percentage (right)
0.2
0.7
0.7
0.8
Pulse wave peak to peak time
0.2
0.2
0.2
-0.5
Mouth/teeth dental problems: Loose teeth
0.2
0.3
0.3
0.5
Migraine (self-reported)
0.2
0.3
0.3
-0.5
Leg fat mass (right)
0.2
0.6
0.6
-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)
0.2
0.2
0.2
-0.4
Arm fat percentage (left)
0.2
1.0
1.0
1.0
Diabetes diagnosed by doctor
0.2
0.3
0.3
-0.5
Commuting to job workplace: Walk
0.2
0.3
0.3
-0.5
Breast cancer (self-reported)
0.2
0.2
0.2
-0.4
Medication: Paracetamol
0.2
0.3
0.3
-0.6
Medication: Atorvastatin
0.2
0.3
0.3
0.5
Myopia
0.2
0.3
0.3
0.6
Pain experienced in last month
0.2
0.4
0.4
0.6
Depressed Affect (Nagel 2018)
0.1
0.1
0.1
-0.3
Breast Cancer
0.1
0.2
0.2
0.5
Waist Hip Ratio (WHR)
0.1
0.7
0.7
0.8
Allergy or Eczema
0.1
0.4
0.4
0.6
Type 2 Diabetes (T2D) (2018)
0.1
0.1
0.1
-0.3
Hair Pigment
0.1
2.6
2.6
-1.6
Tanning
0.1
1.6
1.6
-1.3
Heel bone mineral density (BMD) T-score, automated (left)
0.1
0.2
0.2
0.4
Tinnitus: Yes, but not now, but have in the past
0.1
0.1
0.1
0.3
Qualifications: CSEs or equivalent
0.1
0.2
0.2
0.4
Medication: Levothyroxine sodium
0.1
0.2
0.2
0.4
Frequency of tenseness / restlessness in last 2 weeks
0.1
0.1
0.1
-0.3
Forced vital capacity (FVC)
0.1
0.4
0.4
-0.6
Financial difficulties in last 2 years
0.1
0.1
0.1
0.3
Mouth/teeth dental problems
0.1
0.2
0.2
0.4
Pain all over the body in last month
0.1
0.1
0.1
-0.2
Father’s age at death
0.1
0.1
0.1
-0.3
Medication: Lansoprazole
0.1
0.1
0.1
-0.3
Lung cancer (father)
0.1
0.2
0.2
-0.4
Medication: Amlodipine
0.1
0.2
0.2
0.4
High blood pressure (siblings)
0.1
0.2
0.2
0.4
Eye problems/disorders: None of the above
0.1
0.1
0.1
0.4
Emphysema/chronic bronchitis
0.1
0.2
0.2
0.4
Medication: Blood pressure
0.1
0.1
0.1
0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria
0.1
0.2
0.2
-0.4
Number of full sisters
0.1
0.1
0.1
-0.4
Family relationship satisfaction
0.1
0.2
0.2
0.4
Average weekly red wine intake
0.1
0.2
0.2
0.4
Medication: Aspirin
0.1
0.1
0.1
0.3
Miserableness
0.1
0.2
0.2
-0.5
Financial situation satisfaction
0.1
0.1
0.1
0.3
Tinnitus: Yes, now most or all of the time
0.1
0.1
0.1
-0.3
Leg fat percentage (left)
0.1
0.3
0.3
0.5
Average weekly beer plus cider intake
0.1
0.1
0.1
0.3
Risk taking
0.1
0.2
0.2
0.4
Pack years of smoking
0.1
0.2
0.2
-0.4
Schizophrenia vs Biploar Disorder
0.0
0.0
0.0
-0.2
Alzheimer’s Disease (in mother)
0.0
0.0
0.0
-0.2
Ulcerative Colitis (UC)
0.0
0.0
0.0
-0.0
HDL Cholesterol
0.0
0.0
0.0
0.1
Lupus
0.0
0.0
0.0
0.1
Type 2 Diabetes (T2D) (2012)
0.0
0.0
0.0
0.2
Ulcerative Colitis
0.0
0.0
0.0
0.2
Systolic Blood Pressure
0.0
0.1
0.1
0.3
Hypothyroidism (self reported)
0.0
0.0
0.0
-0.0
Hand grip strength (left)
0.0
0.1
0.1
-0.3
Number of treatments/medications taken
0.0
0.0
0.0
0.1
Frequency of depressed mood in last 2 weeks
0.0
0.0
0.0
0.2
Systolic blood pressure, automated reading
0.0
0.0
0.0
-0.2
Supplements: Zinc
0.0
0.0
0.0
0.2
Medication: Metformin
0.0
0.0
0.0
-0.1
Current tobacco smoking
0.0
0.0
0.0
-0.2
Relative age voice broke
0.0
0.0
0.0
-0.0
Serious illness, injury or assault to yourself
0.0
0.0
0.0
0.0
Multivitamins +/- minerals
0.0
0.0
0.0
0.1
Stomach or abdominal pain in last month
0.0
0.0
0.0
-0.2
High blood pressure (mother)
0.0
0.0
0.0
-0.1
Trunk fat mass
0.0
0.0
0.0
0.2
Diabetes (self-reported)
0.0
0.1
0.1
0.3
Hayfever/allergic rhinitis (self-reported)
0.0
0.0
0.0
-0.1
Medication: Ramipril
0.0
0.0
0.0
0.0
Number of live births
0.0
0.0
0.0
0.2
Happiness
0.0
0.0
0.0
0.1
Serious illness, injury or assault of a close relative in last 2 years
0.0
0.0
0.0
0.1
Illnesses of mother
0.0
0.0
0.0
0.2
Pulse wave Arterial Stiffness index
0.0
0.0
0.0
0.2
Tense / ‘highly strung’
0.0
0.0
0.0
0.0
Ever highly irritable/argumentative for 2 days
0.0
0.0
0.0
-0.1
Glaucoma (self-reported)
0.0
0.0
0.0
-0.0
Medication: Ventolin 100micrograms inhaler
0.0
0.0
0.0
-0.1
Birth weight
0.0
0.1
0.1
-0.2
Chronic bronchitis/emphysema (mother)
0.0
0.0
0.0
0.1
Wheeze or whistling in the chest in last year
0.0
0.0
0.0
-0.1
Neck or shoulder pain in last month
0.0
0.1
0.1
-0.2
Medication: Ibuprofen
0.0
0.1
0.1
-0.2
Mean time to correctly identify matches
0.0
0.0
0.0
-0.1
Whole body fat mass
0.0
0.1
0.1
-0.3
Overall health rating
0.0
0.0
0.0
0.2
Chest pain or discomfort
0.0
0.1
0.1
-0.2
Age at last live birth
0.0
0.0
0.0
0.1
Leg pain on walking
0.0
0.0
0.0
-0.0
Illness, injury, bereavement, stress in last 2 years
0.0
0.0
0.0
-0.1
Medication: Aspirin
0.0
0.0
0.0
0.2
Supplements: Vitamin C
0.0
0.0
0.0
0.2
Handedness (chirality/laterality): Left-handed
0.0
0.0
0.0
-0.1
Loneliness, isolation
0.0
0.0
0.0
0.1
Osteoporosis (self-reported)
0.0
0.0
0.0
-0.1
Smoking status: Current
0.0
0.0
0.0
-0.1
Wears glasses or contact lenses
0.0
0.0
0.0
0.1
Commuting to job workplace: Public transport
0.0
0.0
0.0
-0.0
Eye problems/disorders: Glaucoma
0.0
0.0
0.0
-0.2
Age started oral contraceptive pill
0.0
0.0
0.0
-0.0
Diastolic blood pressure, automated reading
0.0
0.1
0.1
-0.3
Heart disease (siblings)
0.0
0.0
0.0
-0.2