Hub : Genes

LTA4H

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.5069	0.0704	4.7e-10	0.257	NA	0.383	NA	0.433	9.8e-10	NA	8.9e-15	NA	4.6e-17
2	GTEx	Brain Caudate basal ganglia	0.2470	0.0870	4.5e-03	0.010	NA	-0.010	NA	0.005	1.6e-01	NA	7.9e-01	NA	2.2e-01
3	GTEx	Muscle Skeletal	0.1985	0.0437	1.5e-07	0.044	NA	0.082	NA	0.077	3.9e-05	NA	2.1e-08	NA	5.7e-08
4	METSIM	Adipose	0.0987	0.0273	1.5e-06	0.044	0.043	0.045	0.043	0.036	3.3e-07	4.8e-07	2.2e-07	4.3e-07	3.6e-06
5	NTR	Blood	0.1143	0.0197	9.4e-16	0.057	0.069	0.084	0.078	0.076	6.4e-18	3.1e-21	1.2e-25	6.4e-24	2.5e-23
6	YFS	Blood	0.5613	0.0303	0.0e+00	0.299	0.502	0.528	0.522	0.520	8.7e-100	3.0e-193	8.6e-208	2.1e-204	1.9e-203
7	TCGA	Breast Invasive Carcinoma	0.0381	0.0135	3.5e-05	0.038	0.022	0.031	NA	0.033	3.0e-08	1.7e-05	4.9e-07	NA	2.2e-07
8	TCGA	Glioblastoma Multiforme	0.2130	0.1050	6.4e-03	0.003	-0.002	0.001	NA	-0.006	2.5e-01	3.6e-01	3.0e-01	NA	5.5e-01
9	TCGA	Prostate Adenocarcinoma	0.0624	0.0281	1.0e-03	0.021	0.008	0.005	NA	0.013	2.5e-03	3.9e-02	9.8e-02	NA	1.5e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.7	2.4	-0.5	0.9	0.2	-1.6	-1.2	-1.2	0.1	-0.5	-0.2
Bipolar Disorder or Schizophrenia	0.3	0.6	3.2	0.1	1.8	-0.5	-1.1	-0.5	-0.5	0.5	-0.3	0.3
Depressed Affect (Nagel 2018)	0.5	1.0	3.1	0.1	0.6	-1.7	-0.4	0.5	0.7	-1.8	-0.0	-1.4
Depression (Nagel 2018)	0.5	0.8	2.1	1.0	1.4	-1.4	0.7	-0.2	0.0	0.1	0.9	0.8
Intelligence (Savage-Jansen 2018)	0.3	1.1	3.0	-1.3	-0.8	1.7	-0.1	-0.0	-0.1	-0.7	-1.7	-0.9
Neuroticism (Nagel 2018)	0.6	1.3	4.3	0.7	0.1	-2.1	0.3	0.5	0.6	-2.0	0.7	-1.3
Schizophrenia (2018)	0.2	0.5	2.5	0.6	1.6	-0.8	-0.1	0.3	0.3	0.5	-0.0	0.6
Schizophrenia vs Biploar Disorder	1.0	1.3	2.8	1.3	1.3	-1.7	0.8	1.0	1.5	-1.1	0.7	-0.3
Worry (Nagel 2018)	0.5	1.1	3.4	1.5	-0.2	-1.3	0.8	0.7	0.9	-0.9	1.8	-0.1
Alzheimer’s Disease (in mother)	1.1	1.3	5.6	1.1	0.6	-0.6	-0.8	1.3	2.4	-1.0	0.7	-0.8
Alzheimer’s Disease (in father)	0.5	0.5	2.0	0.1	0.6	-0.7	-0.6	-1.4	-0.6	0.7	-0.2	0.6
Alzheimer’s Disease (including proxy)	0.4	0.5	1.9	0.9	1.0	-0.8	-0.3	0.1	1.4	-0.3	0.2	-0.2
Crohns Disease (2017)	0.3	0.7	2.2	-0.7	0.1	-1.5	0.6	0.4	0.8	-1.1	0.3	-1.2
Irritable Bowel Disease (IBD)	0.7	1.6	3.9	-1.8	-0.5	-0.3	0.7	1.1	1.4	-1.6	-0.5	-2.0
Ulcerative Colitis (UC)	1.3	2.5	7.2	-2.7	-1.0	1.1	0.7	1.6	1.6	-1.5	-1.2	-2.0
Major Depression (MDD)	0.6	0.8	1.8	0.3	0.9	1.1	-0.2	1.1	1.4	-0.9	-0.7	-0.8
Reaction Time	0.5	1.0	3.5	0.2	-1.0	-0.3	0.1	1.9	1.2	-1.2	0.0	-1.3
Verbal and Numeric Reasoning (VNR)	0.9	2.1	5.0	-1.1	-1.2	2.2	-2.2	-0.3	-0.8	-0.8	-2.1	-0.9
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.2	0.3	0.7	-0.7	0.2	-0.8	-0.0	0.3	-0.1	-0.8	-0.6	-0.6
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.2	0.3	1.9	-0.5	0.6	0.2	1.4	0.4	0.1	-0.4	0.1	-0.5
Bipolar Disorder (2011)	2.6	2.5	8.7	-3.0	0.5	1.1	-1.6	-0.6	-0.6	-0.5	-2.4	-1.8
Body Mass Index (BMI) (2010)	0.5	0.7	4.8	0.5	-1.0	0.0	-2.2	-0.1	-0.2	0.4	-0.2	0.6
Coronary Artery Disease (CAD)	1.6	1.9	7.9	-2.5	2.8	0.4	-0.0	-0.5	-0.5	-0.1	-1.6	-0.6
Crohns Disease (2012)	0.8	1.3	3.3	-1.4	-1.4	0.0	-1.0	0.2	0.6	-1.6	-0.9	-1.8
Mean Putamen Volume	0.1	0.1	0.6	-0.2	0.4	-0.4	0.0	-0.1	0.0	-0.4	-0.8	-0.1
Fasting Glucose	1.9	2.3	5.3	0.5	-1.5	1.8	-0.7	-2.1	-2.3	1.5	-0.1	1.6
HbA1C	0.7	0.8	4.5	-0.5	0.0	0.3	-2.1	-0.4	-0.9	0.2	-1.1	-0.2
HDL Cholesterol	0.7	1.1	2.5	1.2	1.2	-0.8	1.6	0.6	1.5	0.3	0.9	0.5
LDL Cholesterol	0.2	0.4	1.4	0.7	1.2	-0.4	0.2	-0.4	-0.2	0.7	0.5	0.6
Lupus	1.1	1.7	8.8	0.7	0.7	0.8	3.0	-1.0	-0.3	1.1	0.9	1.2
Neuroticism (2016)	0.4	0.5	1.7	-0.2	-0.3	-0.1	0.5	-0.8	-0.4	1.3	0.7	1.3
Primary Biliary Cirrhosis	0.3	0.4	2.5	-1.6	-0.6	-0.5	-0.6	-0.5	-0.4	0.1	-0.3	0.0
Rheumatoid Arthritis	0.4	0.5	1.6	-0.6	-1.0	-0.5	1.0	-0.1	0.3	0.4	1.3	0.3
Schizophrenia (2014)	0.3	0.7	2.8	-0.6	1.7	0.2	-0.5	-0.7	-0.8	0.8	-0.5	0.7
Triglycerides	0.2	0.3	1.7	0.3	1.3	0.3	-0.6	0.2	0.1	-0.6	0.1	-0.1
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.3	0.4	0.6	1.5	-0.3	-1.3	-0.5	1.3	0.9	0.9
Ulcerative Colitis	1.7	2.4	5.7	-2.0	-2.4	0.3	-0.7	1.2	1.0	-1.9	-1.2	-2.0
Blood Eosinophil Count	0.3	1.9	7.5	0.6	2.5	-2.7	-1.6	-0.4	-0.0	-0.6	-0.3	-0.3
Blood Platelet Count	0.1	0.7	3.8	-0.2	1.2	-1.9	-0.4	0.9	-0.1	0.1	0.6	0.1
Blood Red Count	0.3	2.7	13.1	-3.6	0.4	-0.7	-0.1	0.3	0.2	-1.1	-2.1	-2.2
Blood White Count	0.2	1.8	5.8	-2.4	2.0	-0.4	-0.6	-1.1	-1.5	0.9	-1.2	0.4
Heel T-Score	0.1	1.0	2.4	-1.4	-1.5	0.5	-1.4	0.4	0.2	-0.9	-0.2	-1.1
BMI	0.4	2.2	9.5	-1.0	-0.7	-0.0	-3.1	-1.6	-1.9	0.7	-1.2	0.4
Height	0.1	2.3	7.2	-0.3	0.3	0.6	2.7	1.7	1.6	-1.6	-1.0	-1.8
Waist Hip Ratio (WHR)	0.3	1.5	5.6	0.5	0.3	-1.9	2.4	0.6	1.0	0.0	1.7	0.5
Systolic Blood Pressure	0.4	1.8	7.0	-2.6	1.2	0.4	-1.7	-1.3	-1.2	-0.5	-1.1	-0.7
Smoking Status	0.5	1.1	5.8	0.5	0.9	-0.5	2.4	-0.0	0.7	0.6	0.9	1.0
Allergy or Eczema	0.8	2.0	8.1	2.9	0.0	-0.3	-0.9	0.9	1.3	-0.2	2.5	0.2
Cardiovascular Disease	0.2	0.6	2.1	-1.4	0.6	0.4	-0.6	-0.3	-0.2	-0.8	-1.1	-0.5
Hypothyroidism (self reported)	0.2	0.5	1.4	1.2	1.1	-0.9	0.3	0.7	0.3	-0.8	0.7	-0.0
Respiratory disease	0.4	0.9	2.7	0.9	1.1	0.1	-0.2	-1.2	-0.9	0.9	1.0	1.6
Type 2 Diabetes (T2D) (2018)	0.7	1.3	4.2	0.1	-0.9	0.5	0.3	-1.5	-0.6	1.9	-0.6	2.0
Lung FEV1/FVC ratio	1.9	9.4	31.7	3.0	3.6	-3.5	0.5	2.7	2.8	-1.3	5.6	-1.2
Lung FVC	0.2	1.0	3.7	-0.1	-0.4	1.9	-1.8	-0.2	-0.1	0.5	-1.3	0.2
Neuroticism	0.1	0.2	0.8	-0.9	-0.7	-0.1	-0.3	-0.4	0.1	-0.4	-0.1	-0.3
Chronotype (morning person)	0.7	1.5	3.8	1.3	-0.5	-0.5	-1.1	1.7	0.9	-2.0	-1.1	-1.1
Hair Pigment	0.1	1.8	4.4	0.4	1.6	-1.2	-1.4	2.1	1.2	-1.7	-0.0	-1.0
Tanning	0.0	0.5	2.0	-0.6	0.1	1.4	-0.8	0.7	0.3	-0.4	-0.8	-0.7
Hand grip strength (left)	0.8	2.2	4.9	-0.1	2.2	-1.0	-0.7	1.8	2.0	-2.0	0.0	-1.4
Number of treatments/medications taken	0.6	1.0	3.0	-0.8	0.8	-0.5	0.2	1.7	1.0	-1.1	-0.4	-1.5
Average weekly spirits intake	0.6	0.8	1.8	0.2	-0.0	-1.1	1.2	0.3	0.7	-1.3	1.0	-1.0
Sensitivity / hurt feelings	0.7	1.2	2.5	-1.1	-0.7	0.5	-1.6	0.2	0.2	-1.2	-1.6	-1.5
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.7	-0.2	1.6	0.2	-0.1	-0.2	-0.3	0.2	0.1	0.3
Hearing difficulty/problems: Yes	0.8	1.2	2.8	0.8	1.0	-0.9	0.8	-1.7	-0.9	1.0	1.4	1.1
Relative age of first facial hair	1.7	3.5	7.6	-0.8	-1.2	-0.8	1.9	2.8	2.5	-2.5	0.2	-2.1
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.3	-1.8	-1.5	0.1	0.1	0.5	0.2	-0.7	-1.1	-1.3
Ever used hormone-replacement therapy (HRT)	2.3	2.9	7.1	-1.3	-1.0	0.2	-2.4	0.7	-0.2	-1.9	-2.6	-2.7
Ever had hysterectomy (womb removed)	0.3	0.4	1.1	0.1	-0.3	-1.0	-0.8	0.7	-0.1	-0.8	-0.1	-0.7
Systolic blood pressure, automated reading	0.5	1.4	4.8	-2.2	0.6	-0.7	-1.3	-0.5	-0.6	-1.3	-0.6	-1.6
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.6	-1.1	-1.0	-0.8	1.9	0.1	0.3	0.7	0.3	0.6
Angina	0.3	0.4	2.1	-0.8	1.5	0.3	0.1	-0.0	-0.5	-0.2	-0.8	-0.1
Medication for hormone replacement therapy	1.7	1.9	5.5	-1.3	-1.8	0.5	0.1	0.4	0.1	-1.4	-2.3	-2.1
Vitamin and mineral supplements	0.8	1.0	2.4	-0.5	0.4	-0.1	-1.3	0.7	0.4	-1.5	-1.4	-1.6
Supplements: Zinc	2.8	3.0	8.5	1.8	2.9	-2.3	1.5	1.1	1.1	-0.3	2.2	0.2
Medication: Co-codamol	0.7	0.8	3.0	0.5	1.2	-0.8	1.7	0.3	0.3	-0.2	0.9	0.6
Medication: Metformin	0.2	0.3	1.3	-0.6	0.5	-0.3	0.0	0.4	0.2	0.6	-1.1	0.6
Diabetes (father)	3.4	4.2	8.7	-2.6	-0.8	2.9	-0.8	-2.1	-2.6	2.3	-2.0	0.9
Diabetes (mother)	1.0	1.3	3.5	-0.6	0.5	1.9	-0.4	-1.3	-1.2	1.7	-0.4	1.2
Severe depression (siblings)	1.4	1.6	3.8	1.9	1.2	0.2	1.1	-0.5	-0.5	1.5	1.1	2.0
Pack years adult smoking proportion	0.7	1.0	2.7	0.4	-0.6	0.4	0.9	-1.2	-0.9	1.6	0.4	1.7
Impedance of leg (right)	0.2	1.1	3.6	-1.6	0.1	1.8	0.4	-0.1	0.2	1.9	-0.3	0.5
Leg fat-free mass (left)	0.1	0.4	1.7	-0.1	-0.5	-0.7	-0.9	0.2	-0.3	-1.3	-0.3	-0.4
Trunk fat percentage	0.6	2.4	6.9	-2.6	-1.4	0.8	-2.4	0.0	-1.0	0.3	-2.2	-0.3
Hand grip strength (right)	0.8	2.1	4.9	0.5	2.2	-0.6	-0.3	1.8	2.0	-1.8	1.0	-1.3
Townsend deprivation index at recruitment	0.9	1.2	3.0	1.3	-0.3	-1.0	1.7	0.6	1.3	-0.5	1.7	0.4
Current tobacco smoking	0.4	0.6	1.1	1.0	-0.8	-0.3	0.7	-0.9	0.0	0.6	0.9	1.0
Average weekly fortified wine intake	0.7	0.8	2.7	-1.0	-1.6	-0.3	-0.8	-0.6	-0.7	-1.0	-0.7	-0.7
Maternal smoking around birth	0.5	0.7	2.5	0.8	-1.0	-1.0	0.5	0.5	0.2	-0.6	1.6	-0.1
Fed-up feelings	0.8	1.5	4.2	-1.9	0.3	-0.5	-0.8	0.3	0.3	-1.3	-2.0	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.9	0.3	1.0	-0.8	-0.9	-0.1	-0.2	0.0	0.7	0.6
Relative age voice broke	1.8	2.8	7.2	0.8	-1.5	-0.7	2.0	2.1	2.7	-2.0	0.5	-1.4
Taking other prescription medications	0.3	0.4	0.8	-0.7	-0.8	-0.9	0.1	0.6	0.1	-0.5	-0.6	-0.7
Age when periods started (menarche)	0.8	2.0	5.4	1.2	-2.3	-1.1	0.9	1.4	2.2	-0.7	0.9	-0.9
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	4.2	0.3	1.4	-2.1	0.3	0.6	0.3	-0.7	0.5	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	5.8	0.9	-0.5	-2.4	-0.6	1.2	1.3	-0.9	2.0	-0.7
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.6	0.7	1.1	-1.3	-1.1	-0.5	-0.1	-0.5	0.1	-0.8
Qualifications: CSEs or equivalent	0.8	1.1	2.4	-1.6	1.0	-1.0	0.5	1.4	1.1	-0.9	-0.3	-1.0
Serious illness, injury or assault to yourself	0.4	0.4	1.2	-0.1	0.9	0.2	0.4	-0.8	-1.1	0.5	-0.7	0.4
High blood pressure	0.4	1.1	3.0	-1.6	-0.1	0.2	-1.0	0.8	0.5	-1.2	-1.7	-1.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.1	1.3	-0.0	-0.0	-1.0	-0.2	0.1	0.2	1.5	0.3
Multivitamins +/- minerals	1.3	1.6	4.2	0.8	0.1	0.8	1.6	-0.8	-0.9	2.0	0.9	2.1
Stomach or abdominal pain in last month	1.9	2.3	8.3	0.9	0.4	-0.5	2.3	-0.6	-0.2	1.4	2.9	2.0
Supplements: Glucosamine	0.9	1.2	4.0	1.0	0.0	-0.7	0.6	1.5	1.1	-2.0	0.0	-1.3
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	7.1	-0.6	-2.7	1.4	1.0	-0.9	0.1	0.2	-0.8	-0.1
Medication: Atenolol	0.4	0.5	1.6	-0.5	0.8	0.2	1.3	0.8	0.4	0.1	-0.8	0.1
Medication: Levothyroxine sodium	0.5	0.8	2.7	1.6	0.4	-1.0	1.1	0.2	0.3	-0.2	1.3	0.5
Sitting height	0.0	0.1	0.3	-0.2	0.6	0.5	-0.0	-0.2	-0.3	-0.2	-0.3	0.2
Chronic bronchitis/emphysema (father)	2.3	2.7	5.3	1.5	0.9	-2.3	0.2	1.6	1.8	-1.8	2.2	-1.3
High blood pressure (mother)	0.7	1.0	4.7	-0.6	0.4	-0.1	-2.2	-1.1	-1.5	0.5	0.3	0.1
Body mass index (BMI)	0.4	1.5	6.5	-1.0	-0.7	-0.7	-2.5	-0.8	-1.9	0.5	-0.4	0.6
Impedance of leg (left)	0.2	0.8	2.6	-1.4	-0.1	1.6	0.2	0.3	0.5	1.4	-0.9	0.1
Leg predicted mass (left)	0.1	0.4	1.7	-0.2	-0.5	-0.6	-1.0	0.1	-0.4	-1.3	-0.3	-0.5
Trunk fat mass	0.4	1.8	4.9	-2.2	-1.3	0.6	-2.2	-0.0	-1.0	0.1	-1.8	-0.3
Waist circumference	0.1	0.5	1.3	-0.6	-0.4	-0.3	-0.8	-0.7	-1.1	0.7	0.0	1.0
Number of incorrect matches in round	0.5	0.8	2.4	-0.8	-0.1	1.2	-1.6	-0.8	-0.4	-0.3	-1.3	-0.5
Past tobacco smoking	0.9	1.6	4.0	-1.2	-1.7	0.9	-2.0	-0.3	-1.0	-0.4	-1.8	-0.9
Alcohol usually taken with meals	1.6	2.5	5.2	-1.0	-2.1	-1.6	1.2	1.6	1.1	-2.1	0.5	-2.3
Nervous feelings	0.5	0.8	3.8	0.4	-0.7	-0.7	1.9	0.4	0.8	0.1	1.4	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.6	0.1	1.9	-0.3	-1.4	-0.1	0.3	-0.1	0.1	0.1
Hearing difficulty/problems with background noise	0.6	0.9	4.6	-0.2	2.1	-0.1	-1.2	-0.8	-0.6	-0.6	-0.4	-0.8
Hair/balding pattern: Pattern 2	0.5	0.6	2.3	1.5	-0.5	-0.8	-0.0	0.0	-0.1	-1.0	1.0	-0.3
Had menopause	1.1	1.3	4.1	0.0	-0.5	1.9	-1.5	-1.0	-0.8	-0.3	-2.0	-0.4
Had other major operations	0.4	0.5	2.5	-0.4	1.6	0.0	-0.9	-0.1	-0.7	0.4	-0.9	0.1
Forced vital capacity (FVC)	0.1	0.4	1.2	0.7	0.2	1.1	-0.7	0.2	0.7	-0.2	-0.6	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.3	1.1	-0.4	-1.5	-0.7	1.2	1.2	-0.8	1.1	-0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.2	0.4	0.6	0.2	1.5	-0.2	0.2	0.6	0.7	0.7
Qualifications: None of the above	0.9	2.0	7.0	2.1	0.9	-2.6	0.1	0.2	0.8	-0.0	2.1	0.6
Financial difficulties in last 2 years	1.1	1.5	5.6	0.2	1.2	-2.4	0.5	0.7	0.5	-1.1	1.9	-0.6
Mouth/teeth dental problems	0.2	0.3	1.5	0.1	0.6	-0.0	-1.2	0.1	0.3	-0.6	0.2	-0.0
Heart attack	0.5	0.6	2.4	-0.4	-0.1	-0.4	0.7	0.9	1.6	-1.0	0.3	-0.6
Allergy	0.4	0.8	1.5	-1.0	0.5	0.1	1.2	1.0	1.0	-0.9	-1.1	-1.0
Pain all over the body in last month	0.9	0.9	3.6	-0.6	-1.9	0.7	-0.6	0.6	0.4	-0.2	-1.6	-0.6
Diabetes (self-reported)	0.4	0.6	1.6	0.3	0.5	0.3	0.2	-0.8	-0.3	1.3	-0.9	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.1	0.4	0.5	-1.1	0.3	0.9	0.5	-1.4	0.1	-1.2
Medication: Ramipril	0.4	0.5	1.6	0.4	0.8	-0.2	-0.6	-0.5	-0.5	1.1	0.3	1.3
Medication: Simvastatin	0.8	1.2	4.0	-1.2	2.0	-0.3	-1.5	-0.2	-0.7	-0.9	-0.8	-1.1
Fluid intelligence score	1.1	2.3	6.4	-1.6	-0.8	2.5	-1.8	-0.6	-1.1	0.0	-2.4	-0.3
Illnesses of siblings	0.8	1.1	3.0	0.9	1.3	0.6	-0.4	-0.9	-1.0	1.7	0.3	1.3
Neuroticism score	0.2	0.3	0.9	-0.8	0.2	-0.4	-0.5	0.0	0.1	-1.0	-0.4	-0.9
Weight	0.1	0.6	2.9	-0.7	-0.8	-0.2	-1.7	-0.1	-0.9	-0.3	-0.5	0.1
Impedance of arm (right)	0.3	1.2	2.4	-1.5	-0.8	1.2	1.0	0.8	1.3	-0.2	-1.2	-1.3
Arm fat percentage (right)	0.4	1.7	6.3	-2.2	-0.8	0.0	-2.5	-0.4	-1.4	0.5	-1.0	-0.2
Trunk fat-free mass	0.1	0.7	1.9	0.9	0.4	-1.4	-0.3	0.6	0.1	-1.2	1.0	-0.2
Hip circumference	0.4	1.7	6.2	-1.6	-0.9	0.9	-2.5	-0.5	-1.3	-0.0	-1.7	-0.0
Time employed in main current job	1.2	1.4	3.8	0.3	0.5	-0.5	-1.8	1.3	1.0	-1.6	-0.2	-2.0
Alcohol intake versus 10 years previously	0.5	0.7	3.6	0.9	-0.1	-1.9	-1.0	0.6	0.4	-0.6	-0.2	-0.5
Father’s age at death	0.6	0.8	2.5	0.4	-1.5	1.6	-0.1	0.8	0.5	-0.4	-1.0	-0.5
Worrier / anxious feelings	0.2	0.4	1.0	-0.9	0.5	1.0	-1.0	0.2	0.5	-0.4	-0.4	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.4	0.4	0.0	-1.2	-0.3	1.0	0.8	-1.0	1.0	-0.8
Falls in the last year	0.3	0.4	1.0	0.6	-0.3	-0.1	1.0	1.0	0.3	-0.6	0.6	-0.1
Hair/balding pattern: Pattern 3	0.3	0.4	1.7	-1.2	0.4	-0.4	-0.2	0.0	-0.2	0.5	-1.3	-0.5
Number of live births	1.2	1.7	4.4	0.6	0.5	-2.1	0.7	1.7	2.0	-1.3	0.9	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.6	0.9	1.3	0.1	-0.8	0.2	0.4	-0.1	0.3	-0.2
Pulse rate	0.1	0.2	0.8	0.3	-0.9	-0.2	-0.6	-0.1	0.3	-0.6	0.2	-0.2
Happiness	0.7	0.9	2.6	0.1	-1.1	-1.1	0.1	0.3	1.0	-1.6	0.1	-1.4
Noisy workplace	1.5	1.8	3.7	1.0	0.7	-1.1	1.7	-0.9	-0.9	1.9	1.8	1.7
Qualifications: A levels/AS levels or equivalent	0.8	1.7	5.6	-1.0	0.4	2.4	-1.5	-1.1	-1.4	0.1	-1.8	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.2	-1.1	-0.5	0.4	1.0	-0.7	-0.2	0.6	0.0	0.4
Mouth/teeth dental problems: Dentures	0.7	1.2	2.1	-1.3	0.0	1.3	0.5	-1.4	-1.1	1.4	-1.2	0.8
Asthma	0.4	0.8	1.9	1.0	0.7	-0.7	-0.4	-1.0	-1.0	0.6	0.9	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.0	0.4	0.6	-0.2	1.0	-1.0	-1.4	1.0	0.7	1.3
Medication: Cholesterol lowering	0.5	0.7	3.8	-1.9	0.9	0.7	0.2	-0.2	-0.7	-0.2	-0.8	-0.5
Depression (self-reported)	0.7	0.8	2.1	-1.4	-0.8	1.1	-1.0	0.0	-0.1	-0.1	-1.5	-0.7
Medication: Lansoprazole	1.4	1.6	7.7	2.8	-1.3	-0.3	0.7	0.5	1.3	0.4	1.3	0.9
Prospective memory result	0.5	0.7	3.8	-0.6	0.4	-0.3	-2.0	-0.6	-0.7	-0.5	0.7	-0.5
Lung cancer (father)	0.5	0.6	1.9	-0.7	-0.1	1.0	0.6	0.8	0.0	-0.7	-1.4	-1.0
Illnesses of mother	0.7	0.9	4.1	1.2	-0.2	-0.1	2.0	0.5	0.9	0.4	1.0	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.0	1.5	2.5	-1.0	0.1	0.9	1.3	-1.0	1.3	-0.6
Pulse wave Arterial Stiffness index	0.8	1.0	3.0	0.3	0.1	1.7	0.0	-1.6	-1.0	0.8	-0.6	1.0
Impedance of arm (left)	0.3	1.2	3.0	-1.3	-0.8	1.3	1.7	0.9	1.2	-0.2	-0.9	-0.9
Arm fat mass (right)	0.3	1.2	6.1	-1.4	-0.7	-0.2	-2.5	-0.4	-1.4	0.2	-0.7	0.0
Trunk predicted mass	0.1	0.6	1.8	0.9	0.5	-1.3	-0.3	0.6	0.1	-1.1	1.1	-0.1
Standing height	0.2	1.7	3.8	-0.1	-0.1	0.8	1.4	1.8	1.7	-1.9	-0.5	-1.7
Length of working week for main job	0.5	0.5	1.7	0.4	0.1	-1.3	-0.3	0.9	0.8	-0.3	1.0	-0.4
Exposure to tobacco smoke at home	1.4	1.6	4.5	-1.9	-1.0	0.3	-1.1	0.7	0.5	-1.1	-2.1	-1.3
Breastfed as a baby	1.2	1.5	3.5	-1.9	-0.3	1.0	-0.5	0.8	0.8	-1.3	-1.5	-1.8
Tense / ‘highly strung’	0.4	0.6	2.4	0.7	-0.4	-0.8	0.8	0.3	0.4	-0.9	1.5	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	3.0	-0.0	1.7	-0.7	-0.2	0.3	-0.2	-0.1	-0.2	0.3
Hair/balding pattern: Pattern 4	0.2	0.4	1.4	0.9	0.8	1.2	-0.8	-0.3	0.6	-0.0	-0.0	0.6
Birth weight of first child	0.1	0.2	1.4	0.5	1.2	-0.3	-0.0	0.2	-0.1	-0.1	-0.1	0.1
Peak expiratory flow (PEF)	0.2	0.4	1.1	1.0	0.9	-0.7	-0.0	-0.3	-0.4	-0.1	1.1	0.5
Pulse wave reflection index	0.6	0.7	2.2	0.7	1.5	-1.2	1.2	0.6	0.4	-0.1	0.5	0.5
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.1	1.5	1.0	-1.2	0.4	0.1	0.4	0.5	2.0	0.8
Loud music exposure frequency	0.2	0.2	1.1	1.0	-0.5	-0.3	0.3	0.0	0.1	-0.3	0.1	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.9	-0.4	0.2	1.0	0.5	0.0	-0.3	-0.3	-0.7	-0.6
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	5.2	2.3	0.0	-0.8	1.6	0.1	0.4	0.5	1.3	0.7
Blood clot in the leg (DVT)	0.4	0.5	1.2	0.2	0.2	-1.1	0.6	1.0	0.1	-0.7	-0.6	-1.1
Medication: Paracetamol	0.2	0.4	1.4	-0.9	-0.0	-1.2	0.3	0.7	0.0	-0.0	0.7	-0.5
Headache pain in last month	1.4	2.4	6.6	2.0	1.3	-1.0	2.5	0.5	0.8	0.3	2.6	1.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.4	1.5	-0.3	-1.5	-0.2	-0.0	0.2	-0.0	1.2	0.4
Glaucoma (self-reported)	0.7	0.8	1.5	-1.0	-0.1	1.2	1.1	-1.0	-0.7	1.1	-0.4	0.7
Gout (self-reported)	0.6	0.8	1.5	-1.2	0.6	0.7	-1.0	0.6	0.2	-0.6	-1.2	-1.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.2	2.1	0.6	-1.8	-0.3	0.7	0.8	-0.9	1.1	-0.1
Medication: Amlodipine	0.7	1.0	3.3	-0.1	-0.6	1.8	-0.7	0.8	0.7	-1.2	-0.7	-1.2
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.6	1.0	0.8	0.9	-0.5	-1.3	-1.6	1.5	0.1	1.6
Birth weight	0.5	1.1	4.2	-0.4	2.0	-1.0	1.9	-0.2	-0.3	-0.1	0.7	0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	-0.7	0.2	-0.5	0.1	0.2	-0.5	0.6	0.8	-0.0
High blood pressure (siblings)	0.3	0.4	1.0	-0.1	-1.0	-0.7	0.8	0.6	0.6	-0.8	0.4	-0.4
Forced vital capacity (FVC), Best measure	0.2	0.6	1.9	1.1	1.4	0.1	-0.2	0.5	1.1	-0.6	0.3	-0.3
Body fat percentage	0.6	2.4	8.1	-2.8	-1.2	0.5	-2.5	-0.1	-1.2	0.5	-1.9	-0.3
Leg fat percentage (right)	0.6	2.2	6.9	-2.6	-0.9	0.4	-2.6	-0.6	-1.5	1.1	-1.2	0.3
Arm fat-free mass (right)	0.1	0.4	1.0	0.7	-0.0	-0.8	-0.9	0.1	-0.3	-1.0	0.4	0.1
Exposure to tobacco smoke outside home	0.8	1.0	2.1	0.7	-0.0	-1.4	0.2	1.5	1.4	-1.0	1.0	-0.8
Comparative body size at age 10	0.1	0.4	0.8	0.7	0.2	-0.1	0.4	-0.6	-0.9	0.8	0.5	0.8
Number of full brothers	0.6	0.8	1.5	-1.2	-0.4	0.9	0.2	-0.6	-0.7	1.2	-1.2	1.0
Worry too long after embarrassment	0.1	0.1	0.4	0.5	-0.2	-0.3	0.5	-0.6	-0.2	-0.2	-0.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.9	0.4	1.0	0.8	-1.0	-1.1	-0.9	1.6	-0.2	1.7
Wheeze or whistling in the chest in last year	0.8	1.3	3.2	-0.4	0.4	1.2	-1.8	-1.5	-1.2	1.3	0.4	1.3
Number of children fathered	1.7	2.0	4.6	-0.7	-1.1	-1.0	1.1	1.3	1.7	-2.1	-0.2	-2.1
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.6	1.3	0.7	-0.4	0.5	0.6	0.9	-0.7	0.2	-0.8
Age at first live birth	0.4	0.6	1.4	-1.0	-1.2	0.4	0.4	1.0	0.4	-0.9	-0.2	-1.1
Pulse wave peak to peak time	0.6	0.7	2.2	-0.4	-0.0	-1.2	0.0	1.5	0.8	-0.7	0.4	-1.0
Health satisfaction	0.9	1.2	3.7	0.2	-1.5	0.4	-0.9	-1.9	-1.4	0.9	-0.3	0.9
Shortness of breath walking on level ground	1.8	2.1	5.3	0.0	-1.2	0.5	0.5	-2.0	-1.5	2.3	0.7	2.3
Qualifications: College or University degree	0.4	1.1	3.2	-0.6	-1.1	1.8	-0.8	-1.1	-1.1	0.8	-1.2	0.5
Eye problems/disorders: None of the above	0.7	0.8	2.9	1.7	0.2	-1.1	-0.3	-0.4	-0.2	-0.1	1.5	0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.4	-0.3	-1.2	-0.0	0.9	0.4	0.5	-0.1	1.0	-0.3
Emphysema/chronic bronchitis	0.2	0.2	0.7	-0.6	0.8	0.6	-0.8	0.3	-0.2	0.2	0.2	0.2
Medication for pain relief, constipation, heartburn	0.4	0.6	3.6	1.9	-0.3	0.2	0.1	0.0	1.3	-0.4	-0.3	0.0
Neck or shoulder pain in last month	0.1	0.1	0.3	-0.4	0.6	0.1	0.3	-0.4	0.0	0.0	0.1	0.3
Medication: Blood pressure	0.4	0.8	3.0	-1.7	-0.6	1.5	-0.2	0.2	-0.2	-0.0	-1.1	-0.3
Angina (self-reported)	0.4	0.5	2.7	-0.7	1.6	0.5	0.4	0.1	-0.5	-0.2	-0.9	-0.1
Migraine (self-reported)	0.6	0.7	1.5	0.1	0.9	1.2	-0.2	1.2	1.0	-0.1	1.0	-0.4
Medication: Ibuprofen	0.7	0.8	3.1	-0.5	0.8	-0.5	0.8	-0.9	-1.7	0.7	0.3	0.9
Medication: Allopurinol	0.9	1.2	5.3	-2.3	-0.0	0.8	-1.2	0.7	0.3	-0.4	-1.3	-0.9
Medication: Omeprazole	3.7	4.4	10.8	-2.7	-0.4	-0.1	-1.8	2.3	1.6	-2.7	-1.7	-3.3
Medication: Seretide 50 evohaler	0.3	0.3	1.0	-0.4	0.4	-0.5	-0.3	1.0	0.3	-0.7	0.2	-0.5
Mean time to correctly identify matches	1.3	2.5	6.8	-0.3	-1.0	-0.7	-0.4	2.6	1.7	-2.2	-0.2	-2.4
Heart disease (mother)	0.5	0.6	1.6	0.4	-0.0	-1.1	0.1	0.7	0.6	-1.3	-1.3	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.0	1.7	-1.4	-0.2	-0.7	-1.7	-0.8	0.6	-0.3	1.6
Whole body fat mass	0.5	2.1	6.6	-2.3	-1.2	0.4	-2.6	-0.4	-1.4	0.3	-1.8	-0.1
Leg fat mass (right)	0.5	1.9	7.6	-1.9	-0.9	0.4	-2.8	-0.8	-1.6	0.7	-1.2	0.3
Arm predicted mass (right)	0.1	0.4	1.0	0.7	-0.0	-0.8	-1.0	0.0	-0.5	-0.8	0.6	0.2
Pulse rate, automated reading	0.4	1.3	3.7	0.8	0.1	-0.5	-0.1	-1.1	-0.7	1.7	1.6	1.9
Alcohol intake frequency.	0.3	0.6	1.5	1.1	1.2	0.2	-0.3	-0.5	-0.3	1.0	-0.6	0.9
Comparative height size at age 10	0.1	0.6	2.4	-0.6	1.0	1.6	0.6	-0.2	-0.3	-0.3	-0.9	-0.3
Number of full sisters	0.2	0.3	0.9	0.1	0.6	0.1	-0.9	0.3	0.4	-0.3	0.9	-0.1
Suffer from ‘nerves’	0.6	0.9	2.3	1.5	0.5	-0.5	1.5	0.1	-0.1	0.3	1.4	1.2
Overall health rating	0.4	0.8	3.7	-0.4	-0.5	-0.6	-1.9	-1.0	-1.1	0.5	0.5	0.4
Chest pain or discomfort	0.2	0.3	0.8	0.4	0.7	-0.6	-0.2	0.9	0.4	-0.5	-0.2	-0.2
Had major operations	1.2	1.4	3.2	-1.8	0.2	1.8	-0.5	-0.4	-1.5	0.6	-1.7	-0.2
Age at last live birth	0.7	1.0	2.5	0.4	-0.7	-1.0	1.6	1.1	1.0	-0.8	1.3	-0.1
Family relationship satisfaction	0.6	0.8	1.4	-0.9	-1.1	-0.0	-0.7	1.0	0.1	-1.2	-0.9	-1.2
Leg pain on walking	0.4	0.5	1.5	-0.6	-1.2	0.0	-0.9	0.0	0.7	-0.8	-0.3	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.3	-1.1	1.1	-0.2	-0.9	-0.4	-0.5	0.4	0.4	-0.0
Commuting to job workplace: Car/motor vehicle	2.6	2.9	5.5	-2.3	1.5	1.9	-2.4	-1.3	-2.0	0.7	-1.7	-0.6
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	4.9	0.4	-1.5	1.2	-2.2	-1.4	-1.5	1.1	-1.3	0.9
Medication: Aspirin	0.3	0.4	1.6	-1.3	0.7	0.5	-0.4	0.2	-0.3	-0.1	-0.8	-0.1
Supplements: Vitamin C	1.4	1.7	4.5	-1.0	-0.2	0.5	-0.4	-2.1	-2.0	1.7	0.7	1.3
Knee pain experienced in last month	0.3	0.5	2.6	0.7	1.6	0.1	-0.0	0.3	0.0	-0.7	-0.1	-0.6
Hypertension (Self-reported)	0.4	1.0	2.7	-1.6	0.0	0.3	-1.1	0.6	0.5	-1.1	-1.6	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.6	0.0	-1.9	0.9	0.0	0.3	-0.1	0.2	-0.9	-0.4
Illnesses of father: Heart disease	2.0	2.7	6.3	-0.6	-1.1	-1.6	-0.2	1.9	2.3	-2.5	-0.4	-2.3
Illnesses of siblings: Diabetes	0.3	0.4	1.0	-1.0	-0.3	0.8	0.2	-0.2	1.0	-0.4	0.3	-0.4
Smoking status: Previous	0.8	1.1	4.1	-0.1	2.0	-0.7	1.4	0.6	1.2	0.2	1.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	0.8	0.7	-0.5	-0.7	-0.4	-0.4	0.2	0.8	0.6
Whole body fat-free mass	0.1	0.5	1.6	0.6	-0.0	-1.2	-0.5	0.4	-0.1	-1.3	0.6	-0.2
Leg fat-free mass (right)	0.1	0.6	2.8	0.1	-0.5	-0.8	-0.7	0.4	-0.2	-1.7	-0.4	-0.7
Arm fat percentage (left)	0.4	1.8	5.6	-2.2	-1.1	0.3	-2.4	-0.5	-1.6	0.6	-1.1	0.0
Average weekly red wine intake	0.6	0.9	2.6	-0.1	-0.7	1.6	0.2	0.7	0.6	-1.2	-0.9	-1.4
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.8	2.2	-0.1	-1.8	-1.5	0.2	-0.1	-0.9	0.1	-0.4
Mood swings	0.4	0.7	1.3	0.3	0.6	-1.1	-0.3	0.7	0.9	-1.2	-0.8	-1.0
Loneliness, isolation	0.4	0.5	1.4	-1.0	-0.3	-1.2	-0.8	0.1	-0.3	-0.8	-0.6	-0.8
Long-standing illness, disability or infirmity	0.1	0.1	0.3	-0.1	-0.3	0.4	-0.3	0.1	0.1	-0.3	-0.6	-0.5
Ever had bowel cancer screening	0.3	0.3	1.0	0.7	0.4	-1.0	0.7	0.2	0.1	-0.1	0.6	0.2
Diabetes diagnosed by doctor	0.5	0.9	3.2	0.8	-0.2	-0.1	0.3	-1.0	-0.6	1.6	-0.2	1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.9	-0.2	0.8	-1.0	0.7	-0.0	0.5	-0.2	-0.5	-0.4
Friendships satisfaction	0.9	1.1	3.2	0.0	-0.5	0.5	-1.8	-1.5	-1.6	0.5	-0.3	0.7
Qualifications: nursing, teaching	0.6	1.0	2.6	-0.4	0.3	1.3	-0.4	0.6	0.8	-1.0	-1.6	-1.4
Commuting to job workplace: Walk	2.2	2.4	4.7	2.2	-0.1	-1.5	2.1	1.6	2.0	-0.2	1.9	0.4
Eye problems/disorders: Cataract	1.1	1.3	3.3	-1.8	1.1	1.8	-0.6	-0.4	-0.7	0.8	-1.4	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	0.8	0.6	-1.0	-0.3	0.2	0.3	-0.7	0.1	-0.2
Medication for cholesterol	1.1	1.6	3.7	1.2	0.0	0.8	0.7	-1.2	-0.9	1.8	1.6	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.8	0.0	0.4	-0.3	0.9	-0.0	-0.7	-0.1	0.9	0.3
Back pain experienced in last month	1.0	1.4	6.2	-1.0	2.5	-1.7	0.5	-0.3	-0.3	0.3	1.1	0.8
Mineral and other dietary supplements	0.1	0.1	0.4	-0.1	0.6	-0.1	0.3	-0.3	-0.0	0.6	0.4	0.3
Breast cancer (self-reported)	0.8	1.0	3.1	0.2	-1.0	-0.5	1.8	0.9	0.6	-1.1	-0.8	-1.2
Asthma (self-reported)	0.3	0.7	1.3	0.7	0.9	-0.7	-0.4	-1.1	-1.1	0.6	0.6	1.1
Osteoporosis (self-reported)	0.7	0.9	4.0	0.3	2.0	-0.2	0.4	-0.7	-0.5	1.2	0.3	1.4
Osteoarthritis (self-reported)	1.2	1.5	4.4	0.1	-0.8	-0.3	1.1	1.5	1.2	-2.1	-0.6	-1.8
Medication: Aspirin	0.3	0.3	1.3	-0.8	1.2	0.8	0.2	-0.0	-0.2	0.5	-0.2	0.5
Medication: Gliclazide	1.5	1.7	4.8	1.5	-0.1	-0.0	1.9	-0.1	0.0	1.9	1.1	2.2
Illnesses of father: None of the above (group 1)	0.6	0.7	2.4	0.5	0.4	0.5	1.5	-0.5	-0.3	1.1	0.1	1.4
Smoking status: Current	0.4	0.7	1.6	1.0	-1.2	-0.2	1.0	-0.8	0.1	0.6	0.6	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.2	0.6	0.6	-1.5	-0.1	0.9	0.8	-0.6	0.7	-0.9
Whole body water mass	0.1	0.4	1.6	0.6	-0.0	-1.0	-0.7	0.3	-0.2	-1.2	0.6	-0.2
Leg predicted mass (right)	0.1	0.5	2.5	0.2	-0.5	-0.8	-0.7	0.4	-0.2	-1.6	-0.5	-0.6
Arm fat mass (left)	0.4	1.5	6.3	-1.5	-0.9	-0.1	-2.5	-0.5	-1.6	0.3	-0.8	0.1
Number of self-reported non-cancer illnesses	0.8	1.4	2.5	-1.2	1.2	-0.9	-1.1	1.3	0.9	-1.5	-0.6	-1.6
Average weekly champagne plus white wine intake	0.6	0.9	3.8	-0.8	-1.9	1.6	0.1	-0.1	-0.4	0.6	-0.5	0.4
Miserableness	0.2	0.3	1.4	0.2	1.1	0.5	-1.2	0.0	0.1	-0.1	0.4	-0.1
Guilty feelings	1.1	1.6	5.7	0.1	1.3	-2.4	0.9	1.0	1.3	-1.5	0.4	-1.2
Wears glasses or contact lenses	0.6	0.7	3.1	0.1	1.8	-0.2	1.1	0.8	0.7	-0.3	-0.3	-0.6
Ever taken oral contraceptive pill	1.0	1.2	5.0	0.5	1.0	-1.4	-0.1	0.9	1.0	-0.6	2.2	-0.4
Hearing aid user	0.6	0.6	1.6	-0.8	-1.0	1.3	0.5	-0.4	-0.2	0.9	-0.9	0.5
Mother’s age at death	2.9	3.7	6.9	0.2	-1.6	-0.7	2.0	2.6	2.6	-2.3	1.2	-2.3
Financial situation satisfaction	1.0	1.2	3.8	1.2	0.9	-2.0	0.2	1.0	0.9	-0.1	1.7	0.1
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.9	-0.6	1.3	-1.3	-0.4	0.6	0.4	-1.2	-0.5	-1.4
Commuting to job workplace: Public transport	1.8	2.2	6.5	2.4	0.6	0.4	2.5	1.2	1.4	-0.4	1.8	0.4
Eye problems/disorders: Glaucoma	0.5	0.6	1.6	-1.3	-0.5	1.1	0.8	-0.7	-0.7	0.3	-0.9	-0.2
Medication: Blood pressure	0.3	0.6	2.5	-0.3	1.4	-0.5	-1.6	0.1	0.2	-0.5	-0.3	-0.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.2	0.1	-0.2	-0.8	1.0	1.1	0.7	0.3	1.1	0.4
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.2	0.1	-0.2	-0.3	-0.1	0.2	-0.0	-0.3	0.4	-0.1
High cholesterol (Self-reported)	0.3	0.5	1.5	-0.4	0.7	0.3	0.1	0.5	0.3	-1.2	-0.8	-1.0
Medication: Bendroflumethiazide	0.4	0.6	1.8	-1.2	0.5	0.1	-1.3	0.7	0.5	-0.4	-0.6	-0.6
Medication: Paracetamol	0.5	0.8	3.0	-0.7	0.5	-1.7	-0.2	0.9	0.1	-0.3	1.4	-0.7
Medication: Lisinopril	0.4	0.6	1.2	-0.9	-0.9	-0.1	-0.2	1.1	0.5	-0.9	-0.9	-0.7
Medication: Atorvastatin	1.4	1.7	3.7	1.3	0.5	-0.1	1.8	0.2	0.5	1.8	1.9	1.8
Illnesses of father: High blood pressure	0.3	0.3	1.1	0.7	0.7	-0.3	-1.1	-0.2	-0.2	-0.2	0.7	0.2
Alcohol drinker status: Never	0.4	0.4	1.5	-0.4	1.1	-0.1	0.3	-1.2	-0.8	0.6	0.1	0.1
Ever smoked	1.4	2.4	6.4	2.5	1.3	-1.3	2.2	0.5	0.9	0.7	1.7	1.6
Basal metabolic rate	0.1	0.4	1.1	0.2	-0.2	-0.9	-1.0	0.3	-0.4	-1.1	0.2	-0.2
Leg fat percentage (left)	0.7	2.4	8.0	-2.7	-0.9	0.2	-2.8	-0.3	-1.3	0.7	-1.8	-0.2
Arm fat-free mass (left)	0.1	0.5	1.5	0.7	0.1	-1.0	-1.2	0.2	-0.3	-0.6	0.8	0.3
Number of operations (self-reported)	0.7	1.0	3.5	-1.0	0.5	0.3	-0.8	1.0	0.2	-0.8	-1.9	-1.3
Average weekly beer plus cider intake	1.0	1.4	3.5	-0.6	1.9	1.1	-1.8	-1.4	-1.2	0.7	-0.8	0.6
Irritability	1.0	1.6	4.8	-1.9	-1.1	-0.4	-0.3	0.7	0.2	-1.8	-1.1	-2.2
Risk taking	1.0	1.4	6.1	2.5	0.1	-1.0	0.2	-0.2	-0.7	1.0	1.7	1.0
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.6	0.9	-1.0	0.9	0.4	1.3	1.2	-0.5	-0.0	-0.5
Fractured/broken bones in last 5 years	0.7	0.9	3.0	1.7	0.9	-0.0	1.3	-0.4	-0.1	0.3	1.3	0.6
Age started oral contraceptive pill	1.7	2.2	5.5	-1.3	-0.7	1.1	-0.8	1.4	1.2	-2.1	-1.3	-2.3
Diastolic blood pressure, automated reading	0.6	1.7	4.8	-1.7	1.3	-1.6	-2.2	-0.1	-0.6	-1.0	-0.9	-1.0
Ever depressed for a whole week	0.8	0.9	3.0	1.1	0.3	-0.6	1.4	0.3	0.0	0.5	1.7	1.2
Unable to work because of sickness or disability	1.1	1.5	7.0	0.8	0.3	-0.9	-0.0	-0.7	-0.3	1.3	2.6	1.5
Commuting to job workplace: Cycle	0.7	0.9	3.1	1.5	0.0	-0.8	1.8	0.1	0.7	-0.2	0.6	1.1
Myopia	0.5	0.8	2.0	1.4	0.2	-1.4	1.2	0.6	0.8	-0.5	0.3	0.3
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.3	1.4	-0.3	-0.0	0.9	-0.7	-0.3	1.0	1.5	0.9
Cholesterol lowering medication	0.4	0.6	1.8	-0.2	0.7	-0.8	-0.2	1.0	0.8	-1.4	-0.0	-1.0
Medication: Omeprazole (e.g. Zanprol)	3.9	4.7	9.8	-2.4	-1.8	0.4	-2.6	2.1	1.3	-2.6	-2.0	-3.1
Pain experienced in last month	0.4	0.7	1.5	-0.8	-1.2	0.0	-1.0	-0.1	-0.0	-0.7	-1.0	-1.2
Supplements: Calcium	0.5	0.6	1.2	-0.8	0.3	1.1	-0.0	-0.6	-1.1	0.9	-0.9	0.3
Basal cell carcinoma (self-reported)	2.6	3.1	6.7	1.1	2.2	-1.3	0.6	2.6	1.8	-2.2	0.5	-2.0
Heart attack/myocardial infarction (self-reported)	0.4	0.6	2.4	-0.3	-0.2	-0.2	0.5	1.0	1.6	-0.9	0.0	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.2	0.2	-0.0	-1.1	0.9	1.0	0.1	-0.7	-0.5	-1.1
Heart disease (siblings)	1.0	1.3	2.4	-1.2	-0.3	0.1	-0.8	1.3	0.8	-1.4	-1.5	-1.5
Alcohol drinker status: Previous	0.4	0.5	2.1	1.4	-0.5	0.1	1.0	-0.0	0.1	0.4	-0.2	0.9
Pack years of smoking	0.5	0.7	1.4	0.1	-0.9	0.5	1.1	-0.8	-0.5	1.2	0.1	1.2
Impedance of whole body	0.2	1.3	3.1	-1.7	-0.9	1.8	1.0	0.7	1.0	0.5	-1.2	-0.7
Leg fat mass (left)	0.5	2.1	8.8	-2.0	-0.8	0.3	-3.0	-0.6	-1.5	0.4	-1.5	0.0
Arm predicted mass (left)	0.1	0.4	1.1	0.5	-0.2	-0.9	-1.1	0.4	-0.2	-0.8	0.7	0.0