TWAS hub - LTA4H

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.5069	0.0704	4.7e-10	0.257	NA	0.383	NA	0.433	9.8e-10	NA	8.9e-15	NA	4.6e-17
2	GTEx	Brain Caudate basal ganglia	0.2470	0.0870	4.5e-03	0.010	NA	-0.010	NA	0.005	1.6e-01	NA	7.9e-01	NA	2.2e-01
3	GTEx	Muscle Skeletal	0.1985	0.0437	1.5e-07	0.044	NA	0.082	NA	0.077	3.9e-05	NA	2.1e-08	NA	5.7e-08
4	METSIM	Adipose	0.0987	0.0273	1.5e-06	0.044	0.043	0.045	0.043	0.036	3.3e-07	4.8e-07	2.2e-07	4.3e-07	3.6e-06
5	NTR	Blood	0.1143	0.0197	9.4e-16	0.057	0.069	0.084	0.078	0.076	6.4e-18	3.1e-21	1.2e-25	6.4e-24	2.5e-23
6	YFS	Blood	0.5613	0.0303	0.0e+00	0.299	0.502	0.528	0.522	0.520	8.7e-100	3.0e-193	8.6e-208	2.1e-204	1.9e-203
7	TCGA	Breast Invasive Carcinoma	0.0381	0.0135	3.5e-05	0.038	0.022	0.031	NA	0.033	3.0e-08	1.7e-05	4.9e-07	NA	2.2e-07
8	TCGA	Glioblastoma Multiforme	0.2130	0.1050	6.4e-03	0.003	-0.002	0.001	NA	-0.006	2.5e-01	3.6e-01	3.0e-01	NA	5.5e-01
9	TCGA	Prostate Adenocarcinoma	0.0624	0.0281	1.0e-03	0.021	0.008	0.005	NA	0.013	2.5e-03	3.9e-02	9.8e-02	NA	1.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Medication: Omeprazole (e.g. Zanprol)	3.9	4.7	9.8	-2.4	-1.8	0.4	-2.6	2.1	1.3	-2.6	-2.0	-3.1
Medication: Omeprazole	3.7	4.4	10.8	-2.7	-0.4	-0.1	-1.8	2.3	1.6	-2.7	-1.7	-3.3
Diabetes (father)	3.4	4.2	8.7	-2.6	-0.8	2.9	-0.8	-2.1	-2.6	2.3	-2.0	0.9
Mother’s age at death	2.9	3.7	6.9	0.2	-1.6	-0.7	2.0	2.6	2.6	-2.3	1.2	-2.3
Supplements: Zinc	2.8	3.0	8.5	1.8	2.9	-2.3	1.5	1.1	1.1	-0.3	2.2	0.2
Bipolar Disorder (2011)	2.6	2.5	8.7	-3.0	0.5	1.1	-1.6	-0.6	-0.6	-0.5	-2.4	-1.8
Commuting to job workplace: Car/motor vehicle	2.6	2.9	5.5	-2.3	1.5	1.9	-2.4	-1.3	-2.0	0.7	-1.7	-0.6
Basal cell carcinoma (self-reported)	2.6	3.1	6.7	1.1	2.2	-1.3	0.6	2.6	1.8	-2.2	0.5	-2.0
Ever used hormone-replacement therapy (HRT)	2.3	2.9	7.1	-1.3	-1.0	0.2	-2.4	0.7	-0.2	-1.9	-2.6	-2.7
Chronic bronchitis/emphysema (father)	2.3	2.7	5.3	1.5	0.9	-2.3	0.2	1.6	1.8	-1.8	2.2	-1.3
Commuting to job workplace: Walk	2.2	2.4	4.7	2.2	-0.1	-1.5	2.1	1.6	2.0	-0.2	1.9	0.4
Illnesses of father: Heart disease	2.0	2.7	6.3	-0.6	-1.1	-1.6	-0.2	1.9	2.3	-2.5	-0.4	-2.3
Fasting Glucose	1.9	2.3	5.3	0.5	-1.5	1.8	-0.7	-2.1	-2.3	1.5	-0.1	1.6
Lung FEV1/FVC ratio	1.9	9.4	31.7	3.0	3.6	-3.5	0.5	2.7	2.8	-1.3	5.6	-1.2
Stomach or abdominal pain in last month	1.9	2.3	8.3	0.9	0.4	-0.5	2.3	-0.6	-0.2	1.4	2.9	2.0
Relative age voice broke	1.8	2.8	7.2	0.8	-1.5	-0.7	2.0	2.1	2.7	-2.0	0.5	-1.4
Shortness of breath walking on level ground	1.8	2.1	5.3	0.0	-1.2	0.5	0.5	-2.0	-1.5	2.3	0.7	2.3
Commuting to job workplace: Public transport	1.8	2.2	6.5	2.4	0.6	0.4	2.5	1.2	1.4	-0.4	1.8	0.4
Ulcerative Colitis	1.7	2.4	5.7	-2.0	-2.4	0.3	-0.7	1.2	1.0	-1.9	-1.2	-2.0
Relative age of first facial hair	1.7	3.5	7.6	-0.8	-1.2	-0.8	1.9	2.8	2.5	-2.5	0.2	-2.1
Medication for hormone replacement therapy	1.7	1.9	5.5	-1.3	-1.8	0.5	0.1	0.4	0.1	-1.4	-2.3	-2.1
Number of children fathered	1.7	2.0	4.6	-0.7	-1.1	-1.0	1.1	1.3	1.7	-2.1	-0.2	-2.1
Age started oral contraceptive pill	1.7	2.2	5.5	-1.3	-0.7	1.1	-0.8	1.4	1.2	-2.1	-1.3	-2.3
Coronary Artery Disease (CAD)	1.6	1.9	7.9	-2.5	2.8	0.4	-0.0	-0.5	-0.5	-0.1	-1.6	-0.6
Alcohol usually taken with meals	1.6	2.5	5.2	-1.0	-2.1	-1.6	1.2	1.6	1.1	-2.1	0.5	-2.3
Noisy workplace	1.5	1.8	3.7	1.0	0.7	-1.1	1.7	-0.9	-0.9	1.9	1.8	1.7
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	4.9	0.4	-1.5	1.2	-2.2	-1.4	-1.5	1.1	-1.3	0.9
Medication: Gliclazide	1.5	1.7	4.8	1.5	-0.1	-0.0	1.9	-0.1	0.0	1.9	1.1	2.2
Severe depression (siblings)	1.4	1.6	3.8	1.9	1.2	0.2	1.1	-0.5	-0.5	1.5	1.1	2.0
Medication: Lansoprazole	1.4	1.6	7.7	2.8	-1.3	-0.3	0.7	0.5	1.3	0.4	1.3	0.9
Exposure to tobacco smoke at home	1.4	1.6	4.5	-1.9	-1.0	0.3	-1.1	0.7	0.5	-1.1	-2.1	-1.3
Headache pain in last month	1.4	2.4	6.6	2.0	1.3	-1.0	2.5	0.5	0.8	0.3	2.6	1.0
Supplements: Vitamin C	1.4	1.7	4.5	-1.0	-0.2	0.5	-0.4	-2.1	-2.0	1.7	0.7	1.3
Medication: Atorvastatin	1.4	1.7	3.7	1.3	0.5	-0.1	1.8	0.2	0.5	1.8	1.9	1.8
Ever smoked	1.4	2.4	6.4	2.5	1.3	-1.3	2.2	0.5	0.9	0.7	1.7	1.6
Ulcerative Colitis (UC)	1.3	2.5	7.2	-2.7	-1.0	1.1	0.7	1.6	1.6	-1.5	-1.2	-2.0
Multivitamins +/- minerals	1.3	1.6	4.2	0.8	0.1	0.8	1.6	-0.8	-0.9	2.0	0.9	2.1
Mean time to correctly identify matches	1.3	2.5	6.8	-0.3	-1.0	-0.7	-0.4	2.6	1.7	-2.2	-0.2	-2.4
Time employed in main current job	1.2	1.4	3.8	0.3	0.5	-0.5	-1.8	1.3	1.0	-1.6	-0.2	-2.0
Number of live births	1.2	1.7	4.4	0.6	0.5	-2.1	0.7	1.7	2.0	-1.3	0.9	-0.6
Breastfed as a baby	1.2	1.5	3.5	-1.9	-0.3	1.0	-0.5	0.8	0.8	-1.3	-1.5	-1.8
Had major operations	1.2	1.4	3.2	-1.8	0.2	1.8	-0.5	-0.4	-1.5	0.6	-1.7	-0.2
Osteoarthritis (self-reported)	1.2	1.5	4.4	0.1	-0.8	-0.3	1.1	1.5	1.2	-2.1	-0.6	-1.8
Alzheimer’s Disease (in mother)	1.1	1.3	5.6	1.1	0.6	-0.6	-0.8	1.3	2.4	-1.0	0.7	-0.8
Lupus	1.1	1.7	8.8	0.7	0.7	0.8	3.0	-1.0	-0.3	1.1	0.9	1.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	7.1	-0.6	-2.7	1.4	1.0	-0.9	0.1	0.2	-0.8	-0.1
Had menopause	1.1	1.3	4.1	0.0	-0.5	1.9	-1.5	-1.0	-0.8	-0.3	-2.0	-0.4
Financial difficulties in last 2 years	1.1	1.5	5.6	0.2	1.2	-2.4	0.5	0.7	0.5	-1.1	1.9	-0.6
Fluid intelligence score	1.1	2.3	6.4	-1.6	-0.8	2.5	-1.8	-0.6	-1.1	0.0	-2.4	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.0	1.7	-1.4	-0.2	-0.7	-1.7	-0.8	0.6	-0.3	1.6
Eye problems/disorders: Cataract	1.1	1.3	3.3	-1.8	1.1	1.8	-0.6	-0.4	-0.7	0.8	-1.4	0.2
Medication for cholesterol	1.1	1.6	3.7	1.2	0.0	0.8	0.7	-1.2	-0.9	1.8	1.6	1.9
Guilty feelings	1.1	1.6	5.7	0.1	1.3	-2.4	0.9	1.0	1.3	-1.5	0.4	-1.2
Unable to work because of sickness or disability	1.1	1.5	7.0	0.8	0.3	-0.9	-0.0	-0.7	-0.3	1.3	2.6	1.5
Schizophrenia vs Biploar Disorder	1.0	1.3	2.8	1.3	1.3	-1.7	0.8	1.0	1.5	-1.1	0.7	-0.3
Diabetes (mother)	1.0	1.3	3.5	-0.6	0.5	1.9	-0.4	-1.3	-1.2	1.7	-0.4	1.2
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	5.2	2.3	0.0	-0.8	1.6	0.1	0.4	0.5	1.3	0.7
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.6	1.0	0.8	0.9	-0.5	-1.3	-1.6	1.5	0.1	1.6
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.8	2.2	-0.1	-1.8	-1.5	0.2	-0.1	-0.9	0.1	-0.4
Back pain experienced in last month	1.0	1.4	6.2	-1.0	2.5	-1.7	0.5	-0.3	-0.3	0.3	1.1	0.8
Ever taken oral contraceptive pill	1.0	1.2	5.0	0.5	1.0	-1.4	-0.1	0.9	1.0	-0.6	2.2	-0.4
Financial situation satisfaction	1.0	1.2	3.8	1.2	0.9	-2.0	0.2	1.0	0.9	-0.1	1.7	0.1
Average weekly beer plus cider intake	1.0	1.4	3.5	-0.6	1.9	1.1	-1.8	-1.4	-1.2	0.7	-0.8	0.6
Irritability	1.0	1.6	4.8	-1.9	-1.1	-0.4	-0.3	0.7	0.2	-1.8	-1.1	-2.2
Risk taking	1.0	1.4	6.1	2.5	0.1	-1.0	0.2	-0.2	-0.7	1.0	1.7	1.0
Heart disease (siblings)	1.0	1.3	2.4	-1.2	-0.3	0.1	-0.8	1.3	0.8	-1.4	-1.5	-1.5
Verbal and Numeric Reasoning (VNR)	0.9	2.1	5.0	-1.1	-1.2	2.2	-2.2	-0.3	-0.8	-0.8	-2.1	-0.9
Townsend deprivation index at recruitment	0.9	1.2	3.0	1.3	-0.3	-1.0	1.7	0.6	1.3	-0.5	1.7	0.4
Supplements: Glucosamine	0.9	1.2	4.0	1.0	0.0	-0.7	0.6	1.5	1.1	-2.0	0.0	-1.3
Past tobacco smoking	0.9	1.6	4.0	-1.2	-1.7	0.9	-2.0	-0.3	-1.0	-0.4	-1.8	-0.9
Qualifications: None of the above	0.9	2.0	7.0	2.1	0.9	-2.6	0.1	0.2	0.8	-0.0	2.1	0.6
Pain all over the body in last month	0.9	0.9	3.6	-0.6	-1.9	0.7	-0.6	0.6	0.4	-0.2	-1.6	-0.6
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.1	1.5	1.0	-1.2	0.4	0.1	0.4	0.5	2.0	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.9	0.4	1.0	0.8	-1.0	-1.1	-0.9	1.6	-0.2	1.7
Health satisfaction	0.9	1.2	3.7	0.2	-1.5	0.4	-0.9	-1.9	-1.4	0.9	-0.3	0.9
Medication: Allopurinol	0.9	1.2	5.3	-2.3	-0.0	0.8	-1.2	0.7	0.3	-0.4	-1.3	-0.9
Friendships satisfaction	0.9	1.1	3.2	0.0	-0.5	0.5	-1.8	-1.5	-1.6	0.5	-0.3	0.7
Crohns Disease (2012)	0.8	1.3	3.3	-1.4	-1.4	0.0	-1.0	0.2	0.6	-1.6	-0.9	-1.8
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.3	0.4	0.6	1.5	-0.3	-1.3	-0.5	1.3	0.9	0.9
Allergy or Eczema	0.8	2.0	8.1	2.9	0.0	-0.3	-0.9	0.9	1.3	-0.2	2.5	0.2
Hand grip strength (left)	0.8	2.2	4.9	-0.1	2.2	-1.0	-0.7	1.8	2.0	-2.0	0.0	-1.4
Hearing difficulty/problems: Yes	0.8	1.2	2.8	0.8	1.0	-0.9	0.8	-1.7	-0.9	1.0	1.4	1.1
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.3	-1.8	-1.5	0.1	0.1	0.5	0.2	-0.7	-1.1	-1.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.6	-1.1	-1.0	-0.8	1.9	0.1	0.3	0.7	0.3	0.6
Vitamin and mineral supplements	0.8	1.0	2.4	-0.5	0.4	-0.1	-1.3	0.7	0.4	-1.5	-1.4	-1.6
Hand grip strength (right)	0.8	2.1	4.9	0.5	2.2	-0.6	-0.3	1.8	2.0	-1.8	1.0	-1.3
Fed-up feelings	0.8	1.5	4.2	-1.9	0.3	-0.5	-0.8	0.3	0.3	-1.3	-2.0	-1.7
Age when periods started (menarche)	0.8	2.0	5.4	1.2	-2.3	-1.1	0.9	1.4	2.2	-0.7	0.9	-0.9
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	4.2	0.3	1.4	-2.1	0.3	0.6	0.3	-0.7	0.5	-0.9
Qualifications: CSEs or equivalent	0.8	1.1	2.4	-1.6	1.0	-1.0	0.5	1.4	1.1	-0.9	-0.3	-1.0
Medication: Simvastatin	0.8	1.2	4.0	-1.2	2.0	-0.3	-1.5	-0.2	-0.7	-0.9	-0.8	-1.1
Illnesses of siblings	0.8	1.1	3.0	0.9	1.3	0.6	-0.4	-0.9	-1.0	1.7	0.3	1.3
Qualifications: A levels/AS levels or equivalent	0.8	1.7	5.6	-1.0	0.4	2.4	-1.5	-1.1	-1.4	0.1	-1.8	0.3
Pulse wave Arterial Stiffness index	0.8	1.0	3.0	0.3	0.1	1.7	0.0	-1.6	-1.0	0.8	-0.6	1.0
Exposure to tobacco smoke outside home	0.8	1.0	2.1	0.7	-0.0	-1.4	0.2	1.5	1.4	-1.0	1.0	-0.8
Wheeze or whistling in the chest in last year	0.8	1.3	3.2	-0.4	0.4	1.2	-1.8	-1.5	-1.2	1.3	0.4	1.3
Smoking status: Previous	0.8	1.1	4.1	-0.1	2.0	-0.7	1.4	0.6	1.2	0.2	1.3	0.1
Breast cancer (self-reported)	0.8	1.0	3.1	0.2	-1.0	-0.5	1.8	0.9	0.6	-1.1	-0.8	-1.2
Number of self-reported non-cancer illnesses	0.8	1.4	2.5	-1.2	1.2	-0.9	-1.1	1.3	0.9	-1.5	-0.6	-1.6
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.9	-0.6	1.3	-1.3	-0.4	0.6	0.4	-1.2	-0.5	-1.4
Ever depressed for a whole week	0.8	0.9	3.0	1.1	0.3	-0.6	1.4	0.3	0.0	0.5	1.7	1.2
Irritable Bowel Disease (IBD)	0.7	1.6	3.9	-1.8	-0.5	-0.3	0.7	1.1	1.4	-1.6	-0.5	-2.0
HbA1C	0.7	0.8	4.5	-0.5	0.0	0.3	-2.1	-0.4	-0.9	0.2	-1.1	-0.2
HDL Cholesterol	0.7	1.1	2.5	1.2	1.2	-0.8	1.6	0.6	1.5	0.3	0.9	0.5
Type 2 Diabetes (T2D) (2018)	0.7	1.3	4.2	0.1	-0.9	0.5	0.3	-1.5	-0.6	1.9	-0.6	2.0
Chronotype (morning person)	0.7	1.5	3.8	1.3	-0.5	-0.5	-1.1	1.7	0.9	-2.0	-1.1	-1.1
Sensitivity / hurt feelings	0.7	1.2	2.5	-1.1	-0.7	0.5	-1.6	0.2	0.2	-1.2	-1.6	-1.5
Medication: Co-codamol	0.7	0.8	3.0	0.5	1.2	-0.8	1.7	0.3	0.3	-0.2	0.9	0.6
Pack years adult smoking proportion	0.7	1.0	2.7	0.4	-0.6	0.4	0.9	-1.2	-0.9	1.6	0.4	1.7
Average weekly fortified wine intake	0.7	0.8	2.7	-1.0	-1.6	-0.3	-0.8	-0.6	-0.7	-1.0	-0.7	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	5.8	0.9	-0.5	-2.4	-0.6	1.2	1.3	-0.9	2.0	-0.7
High blood pressure (mother)	0.7	1.0	4.7	-0.6	0.4	-0.1	-2.2	-1.1	-1.5	0.5	0.3	0.1
Happiness	0.7	0.9	2.6	0.1	-1.1	-1.1	0.1	0.3	1.0	-1.6	0.1	-1.4
Mouth/teeth dental problems: Dentures	0.7	1.2	2.1	-1.3	0.0	1.3	0.5	-1.4	-1.1	1.4	-1.2	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.0	0.4	0.6	-0.2	1.0	-1.0	-1.4	1.0	0.7	1.3
Depression (self-reported)	0.7	0.8	2.1	-1.4	-0.8	1.1	-1.0	0.0	-0.1	-0.1	-1.5	-0.7
Illnesses of mother	0.7	0.9	4.1	1.2	-0.2	-0.1	2.0	0.5	0.9	0.4	1.0	0.7
Glaucoma (self-reported)	0.7	0.8	1.5	-1.0	-0.1	1.2	1.1	-1.0	-0.7	1.1	-0.4	0.7
Medication: Amlodipine	0.7	1.0	3.3	-0.1	-0.6	1.8	-0.7	0.8	0.7	-1.2	-0.7	-1.2
Eye problems/disorders: None of the above	0.7	0.8	2.9	1.7	0.2	-1.1	-0.3	-0.4	-0.2	-0.1	1.5	0.3
Medication: Ibuprofen	0.7	0.8	3.1	-0.5	0.8	-0.5	0.8	-0.9	-1.7	0.7	0.3	0.9
Age at last live birth	0.7	1.0	2.5	0.4	-0.7	-1.0	1.6	1.1	1.0	-0.8	1.3	-0.1
Osteoporosis (self-reported)	0.7	0.9	4.0	0.3	2.0	-0.2	0.4	-0.7	-0.5	1.2	0.3	1.4
Leg fat percentage (left)	0.7	2.4	8.0	-2.7	-0.9	0.2	-2.8	-0.3	-1.3	0.7	-1.8	-0.2
Number of operations (self-reported)	0.7	1.0	3.5	-1.0	0.5	0.3	-0.8	1.0	0.2	-0.8	-1.9	-1.3
Fractured/broken bones in last 5 years	0.7	0.9	3.0	1.7	0.9	-0.0	1.3	-0.4	-0.1	0.3	1.3	0.6
Commuting to job workplace: Cycle	0.7	0.9	3.1	1.5	0.0	-0.8	1.8	0.1	0.7	-0.2	0.6	1.1
Neuroticism (Nagel 2018)	0.6	1.3	4.3	0.7	0.1	-2.1	0.3	0.5	0.6	-2.0	0.7	-1.3
Major Depression (MDD)	0.6	0.8	1.8	0.3	0.9	1.1	-0.2	1.1	1.4	-0.9	-0.7	-0.8
Number of treatments/medications taken	0.6	1.0	3.0	-0.8	0.8	-0.5	0.2	1.7	1.0	-1.1	-0.4	-1.5
Average weekly spirits intake	0.6	0.8	1.8	0.2	-0.0	-1.1	1.2	0.3	0.7	-1.3	1.0	-1.0
Trunk fat percentage	0.6	2.4	6.9	-2.6	-1.4	0.8	-2.4	0.0	-1.0	0.3	-2.2	-0.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.6	0.7	1.1	-1.3	-1.1	-0.5	-0.1	-0.5	0.1	-0.8
Hearing difficulty/problems with background noise	0.6	0.9	4.6	-0.2	2.1	-0.1	-1.2	-0.8	-0.6	-0.6	-0.4	-0.8
Father’s age at death	0.6	0.8	2.5	0.4	-1.5	1.6	-0.1	0.8	0.5	-0.4	-1.0	-0.5
Pulse wave reflection index	0.6	0.7	2.2	0.7	1.5	-1.2	1.2	0.6	0.4	-0.1	0.5	0.5
Gout (self-reported)	0.6	0.8	1.5	-1.2	0.6	0.7	-1.0	0.6	0.2	-0.6	-1.2	-1.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.2	2.1	0.6	-1.8	-0.3	0.7	0.8	-0.9	1.1	-0.1
Body fat percentage	0.6	2.4	8.1	-2.8	-1.2	0.5	-2.5	-0.1	-1.2	0.5	-1.9	-0.3
Leg fat percentage (right)	0.6	2.2	6.9	-2.6	-0.9	0.4	-2.6	-0.6	-1.5	1.1	-1.2	0.3
Number of full brothers	0.6	0.8	1.5	-1.2	-0.4	0.9	0.2	-0.6	-0.7	1.2	-1.2	1.0
Pulse wave peak to peak time	0.6	0.7	2.2	-0.4	-0.0	-1.2	0.0	1.5	0.8	-0.7	0.4	-1.0
Migraine (self-reported)	0.6	0.7	1.5	0.1	0.9	1.2	-0.2	1.2	1.0	-0.1	1.0	-0.4
Suffer from ‘nerves’	0.6	0.9	2.3	1.5	0.5	-0.5	1.5	0.1	-0.1	0.3	1.4	1.2
Family relationship satisfaction	0.6	0.8	1.4	-0.9	-1.1	-0.0	-0.7	1.0	0.1	-1.2	-0.9	-1.2
Average weekly red wine intake	0.6	0.9	2.6	-0.1	-0.7	1.6	0.2	0.7	0.6	-1.2	-0.9	-1.4
Qualifications: nursing, teaching	0.6	1.0	2.6	-0.4	0.3	1.3	-0.4	0.6	0.8	-1.0	-1.6	-1.4
Illnesses of father: None of the above (group 1)	0.6	0.7	2.4	0.5	0.4	0.5	1.5	-0.5	-0.3	1.1	0.1	1.4
Average weekly champagne plus white wine intake	0.6	0.9	3.8	-0.8	-1.9	1.6	0.1	-0.1	-0.4	0.6	-0.5	0.4
Wears glasses or contact lenses	0.6	0.7	3.1	0.1	1.8	-0.2	1.1	0.8	0.7	-0.3	-0.3	-0.6
Hearing aid user	0.6	0.6	1.6	-0.8	-1.0	1.3	0.5	-0.4	-0.2	0.9	-0.9	0.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.6	0.9	-1.0	0.9	0.4	1.3	1.2	-0.5	-0.0	-0.5
Diastolic blood pressure, automated reading	0.6	1.7	4.8	-1.7	1.3	-1.6	-2.2	-0.1	-0.6	-1.0	-0.9	-1.0
Bipolar Disorder (2018)	0.5	0.7	2.4	-0.5	0.9	0.2	-1.6	-1.2	-1.2	0.1	-0.5	-0.2
Depressed Affect (Nagel 2018)	0.5	1.0	3.1	0.1	0.6	-1.7	-0.4	0.5	0.7	-1.8	-0.0	-1.4
Depression (Nagel 2018)	0.5	0.8	2.1	1.0	1.4	-1.4	0.7	-0.2	0.0	0.1	0.9	0.8
Worry (Nagel 2018)	0.5	1.1	3.4	1.5	-0.2	-1.3	0.8	0.7	0.9	-0.9	1.8	-0.1
Alzheimer’s Disease (in father)	0.5	0.5	2.0	0.1	0.6	-0.7	-0.6	-1.4	-0.6	0.7	-0.2	0.6
Reaction Time	0.5	1.0	3.5	0.2	-1.0	-0.3	0.1	1.9	1.2	-1.2	0.0	-1.3
Body Mass Index (BMI) (2010)	0.5	0.7	4.8	0.5	-1.0	0.0	-2.2	-0.1	-0.2	0.4	-0.2	0.6
Smoking Status	0.5	1.1	5.8	0.5	0.9	-0.5	2.4	-0.0	0.7	0.6	0.9	1.0
Systolic blood pressure, automated reading	0.5	1.4	4.8	-2.2	0.6	-0.7	-1.3	-0.5	-0.6	-1.3	-0.6	-1.6
Maternal smoking around birth	0.5	0.7	2.5	0.8	-1.0	-1.0	0.5	0.5	0.2	-0.6	1.6	-0.1
Medication: Levothyroxine sodium	0.5	0.8	2.7	1.6	0.4	-1.0	1.1	0.2	0.3	-0.2	1.3	0.5
Number of incorrect matches in round	0.5	0.8	2.4	-0.8	-0.1	1.2	-1.6	-0.8	-0.4	-0.3	-1.3	-0.5
Nervous feelings	0.5	0.8	3.8	0.4	-0.7	-0.7	1.9	0.4	0.8	0.1	1.4	0.1
Hair/balding pattern: Pattern 2	0.5	0.6	2.3	1.5	-0.5	-0.8	-0.0	0.0	-0.1	-1.0	1.0	-0.3
Heart attack	0.5	0.6	2.4	-0.4	-0.1	-0.4	0.7	0.9	1.6	-1.0	0.3	-0.6
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.1	0.4	0.5	-1.1	0.3	0.9	0.5	-1.4	0.1	-1.2
Alcohol intake versus 10 years previously	0.5	0.7	3.6	0.9	-0.1	-1.9	-1.0	0.6	0.4	-0.6	-0.2	-0.5
Medication: Cholesterol lowering	0.5	0.7	3.8	-1.9	0.9	0.7	0.2	-0.2	-0.7	-0.2	-0.8	-0.5
Prospective memory result	0.5	0.7	3.8	-0.6	0.4	-0.3	-2.0	-0.6	-0.7	-0.5	0.7	-0.5
Lung cancer (father)	0.5	0.6	1.9	-0.7	-0.1	1.0	0.6	0.8	0.0	-0.7	-1.4	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.0	1.5	2.5	-1.0	0.1	0.9	1.3	-1.0	1.3	-0.6
Length of working week for main job	0.5	0.5	1.7	0.4	0.1	-1.3	-0.3	0.9	0.8	-0.3	1.0	-0.4
Birth weight	0.5	1.1	4.2	-0.4	2.0	-1.0	1.9	-0.2	-0.3	-0.1	0.7	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.6	1.3	0.7	-0.4	0.5	0.6	0.9	-0.7	0.2	-0.8
Heart disease (mother)	0.5	0.6	1.6	0.4	-0.0	-1.1	0.1	0.7	0.6	-1.3	-1.3	-0.7
Whole body fat mass	0.5	2.1	6.6	-2.3	-1.2	0.4	-2.6	-0.4	-1.4	0.3	-1.8	-0.1
Leg fat mass (right)	0.5	1.9	7.6	-1.9	-0.9	0.4	-2.8	-0.8	-1.6	0.7	-1.2	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.6	0.0	-1.9	0.9	0.0	0.3	-0.1	0.2	-0.9	-0.4
Diabetes diagnosed by doctor	0.5	0.9	3.2	0.8	-0.2	-0.1	0.3	-1.0	-0.6	1.6	-0.2	1.8
Eye problems/disorders: Glaucoma	0.5	0.6	1.6	-1.3	-0.5	1.1	0.8	-0.7	-0.7	0.3	-0.9	-0.2
Medication: Paracetamol	0.5	0.8	3.0	-0.7	0.5	-1.7	-0.2	0.9	0.1	-0.3	1.4	-0.7
Myopia	0.5	0.8	2.0	1.4	0.2	-1.4	1.2	0.6	0.8	-0.5	0.3	0.3
Supplements: Calcium	0.5	0.6	1.2	-0.8	0.3	1.1	-0.0	-0.6	-1.1	0.9	-0.9	0.3
Pack years of smoking	0.5	0.7	1.4	0.1	-0.9	0.5	1.1	-0.8	-0.5	1.2	0.1	1.2
Leg fat mass (left)	0.5	2.1	8.8	-2.0	-0.8	0.3	-3.0	-0.6	-1.5	0.4	-1.5	0.0
Alzheimer’s Disease (including proxy)	0.4	0.5	1.9	0.9	1.0	-0.8	-0.3	0.1	1.4	-0.3	0.2	-0.2
Neuroticism (2016)	0.4	0.5	1.7	-0.2	-0.3	-0.1	0.5	-0.8	-0.4	1.3	0.7	1.3
Rheumatoid Arthritis	0.4	0.5	1.6	-0.6	-1.0	-0.5	1.0	-0.1	0.3	0.4	1.3	0.3
BMI	0.4	2.2	9.5	-1.0	-0.7	-0.0	-3.1	-1.6	-1.9	0.7	-1.2	0.4
Systolic Blood Pressure	0.4	1.8	7.0	-2.6	1.2	0.4	-1.7	-1.3	-1.2	-0.5	-1.1	-0.7
Respiratory disease	0.4	0.9	2.7	0.9	1.1	0.1	-0.2	-1.2	-0.9	0.9	1.0	1.6
Current tobacco smoking	0.4	0.6	1.1	1.0	-0.8	-0.3	0.7	-0.9	0.0	0.6	0.9	1.0
Serious illness, injury or assault to yourself	0.4	0.4	1.2	-0.1	0.9	0.2	0.4	-0.8	-1.1	0.5	-0.7	0.4
High blood pressure	0.4	1.1	3.0	-1.6	-0.1	0.2	-1.0	0.8	0.5	-1.2	-1.7	-1.1
Medication: Atenolol	0.4	0.5	1.6	-0.5	0.8	0.2	1.3	0.8	0.4	0.1	-0.8	0.1
Body mass index (BMI)	0.4	1.5	6.5	-1.0	-0.7	-0.7	-2.5	-0.8	-1.9	0.5	-0.4	0.6
Trunk fat mass	0.4	1.8	4.9	-2.2	-1.3	0.6	-2.2	-0.0	-1.0	0.1	-1.8	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.6	0.1	1.9	-0.3	-1.4	-0.1	0.3	-0.1	0.1	0.1
Had other major operations	0.4	0.5	2.5	-0.4	1.6	0.0	-0.9	-0.1	-0.7	0.4	-0.9	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.3	1.1	-0.4	-1.5	-0.7	1.2	1.2	-0.8	1.1	-0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.2	0.4	0.6	0.2	1.5	-0.2	0.2	0.6	0.7	0.7
Allergy	0.4	0.8	1.5	-1.0	0.5	0.1	1.2	1.0	1.0	-0.9	-1.1	-1.0
Diabetes (self-reported)	0.4	0.6	1.6	0.3	0.5	0.3	0.2	-0.8	-0.3	1.3	-0.9	1.2
Medication: Ramipril	0.4	0.5	1.6	0.4	0.8	-0.2	-0.6	-0.5	-0.5	1.1	0.3	1.3
Arm fat percentage (right)	0.4	1.7	6.3	-2.2	-0.8	0.0	-2.5	-0.4	-1.4	0.5	-1.0	-0.2
Hip circumference	0.4	1.7	6.2	-1.6	-0.9	0.9	-2.5	-0.5	-1.3	-0.0	-1.7	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.4	0.4	0.0	-1.2	-0.3	1.0	0.8	-1.0	1.0	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.2	-1.1	-0.5	0.4	1.0	-0.7	-0.2	0.6	0.0	0.4
Asthma	0.4	0.8	1.9	1.0	0.7	-0.7	-0.4	-1.0	-1.0	0.6	0.9	1.4
Tense / ‘highly strung’	0.4	0.6	2.4	0.7	-0.4	-0.8	0.8	0.3	0.4	-0.9	1.5	-0.0
Blood clot in the leg (DVT)	0.4	0.5	1.2	0.2	0.2	-1.1	0.6	1.0	0.1	-0.7	-0.6	-1.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.4	1.5	-0.3	-1.5	-0.2	-0.0	0.2	-0.0	1.2	0.4
Age at first live birth	0.4	0.6	1.4	-1.0	-1.2	0.4	0.4	1.0	0.4	-0.9	-0.2	-1.1
Qualifications: College or University degree	0.4	1.1	3.2	-0.6	-1.1	1.8	-0.8	-1.1	-1.1	0.8	-1.2	0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.4	-0.3	-1.2	-0.0	0.9	0.4	0.5	-0.1	1.0	-0.3
Medication for pain relief, constipation, heartburn	0.4	0.6	3.6	1.9	-0.3	0.2	0.1	0.0	1.3	-0.4	-0.3	0.0
Medication: Blood pressure	0.4	0.8	3.0	-1.7	-0.6	1.5	-0.2	0.2	-0.2	-0.0	-1.1	-0.3
Angina (self-reported)	0.4	0.5	2.7	-0.7	1.6	0.5	0.4	0.1	-0.5	-0.2	-0.9	-0.1
Pulse rate, automated reading	0.4	1.3	3.7	0.8	0.1	-0.5	-0.1	-1.1	-0.7	1.7	1.6	1.9
Overall health rating	0.4	0.8	3.7	-0.4	-0.5	-0.6	-1.9	-1.0	-1.1	0.5	0.5	0.4
Leg pain on walking	0.4	0.5	1.5	-0.6	-1.2	0.0	-0.9	0.0	0.7	-0.8	-0.3	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.3	-1.1	1.1	-0.2	-0.9	-0.4	-0.5	0.4	0.4	-0.0
Hypertension (Self-reported)	0.4	1.0	2.7	-1.6	0.0	0.3	-1.1	0.6	0.5	-1.1	-1.6	-1.0
Arm fat percentage (left)	0.4	1.8	5.6	-2.2	-1.1	0.3	-2.4	-0.5	-1.6	0.6	-1.1	0.0
Mood swings	0.4	0.7	1.3	0.3	0.6	-1.1	-0.3	0.7	0.9	-1.2	-0.8	-1.0
Loneliness, isolation	0.4	0.5	1.4	-1.0	-0.3	-1.2	-0.8	0.1	-0.3	-0.8	-0.6	-0.8
Smoking status: Current	0.4	0.7	1.6	1.0	-1.2	-0.2	1.0	-0.8	0.1	0.6	0.6	1.0
Arm fat mass (left)	0.4	1.5	6.3	-1.5	-0.9	-0.1	-2.5	-0.5	-1.6	0.3	-0.8	0.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.2	0.1	-0.2	-0.8	1.0	1.1	0.7	0.3	1.1	0.4
Medication: Bendroflumethiazide	0.4	0.6	1.8	-1.2	0.5	0.1	-1.3	0.7	0.5	-0.4	-0.6	-0.6
Medication: Lisinopril	0.4	0.6	1.2	-0.9	-0.9	-0.1	-0.2	1.1	0.5	-0.9	-0.9	-0.7
Alcohol drinker status: Never	0.4	0.4	1.5	-0.4	1.1	-0.1	0.3	-1.2	-0.8	0.6	0.1	0.1
Cholesterol lowering medication	0.4	0.6	1.8	-0.2	0.7	-0.8	-0.2	1.0	0.8	-1.4	-0.0	-1.0
Pain experienced in last month	0.4	0.7	1.5	-0.8	-1.2	0.0	-1.0	-0.1	-0.0	-0.7	-1.0	-1.2
Heart attack/myocardial infarction (self-reported)	0.4	0.6	2.4	-0.3	-0.2	-0.2	0.5	1.0	1.6	-0.9	0.0	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.2	0.2	-0.0	-1.1	0.9	1.0	0.1	-0.7	-0.5	-1.1
Alcohol drinker status: Previous	0.4	0.5	2.1	1.4	-0.5	0.1	1.0	-0.0	0.1	0.4	-0.2	0.9
Bipolar Disorder or Schizophrenia	0.3	0.6	3.2	0.1	1.8	-0.5	-1.1	-0.5	-0.5	0.5	-0.3	0.3
Intelligence (Savage-Jansen 2018)	0.3	1.1	3.0	-1.3	-0.8	1.7	-0.1	-0.0	-0.1	-0.7	-1.7	-0.9
Crohns Disease (2017)	0.3	0.7	2.2	-0.7	0.1	-1.5	0.6	0.4	0.8	-1.1	0.3	-1.2
Primary Biliary Cirrhosis	0.3	0.4	2.5	-1.6	-0.6	-0.5	-0.6	-0.5	-0.4	0.1	-0.3	0.0
Schizophrenia (2014)	0.3	0.7	2.8	-0.6	1.7	0.2	-0.5	-0.7	-0.8	0.8	-0.5	0.7
Blood Eosinophil Count	0.3	1.9	7.5	0.6	2.5	-2.7	-1.6	-0.4	-0.0	-0.6	-0.3	-0.3
Blood Red Count	0.3	2.7	13.1	-3.6	0.4	-0.7	-0.1	0.3	0.2	-1.1	-2.1	-2.2
Waist Hip Ratio (WHR)	0.3	1.5	5.6	0.5	0.3	-1.9	2.4	0.6	1.0	0.0	1.7	0.5
Ever had hysterectomy (womb removed)	0.3	0.4	1.1	0.1	-0.3	-1.0	-0.8	0.7	-0.1	-0.8	-0.1	-0.7
Angina	0.3	0.4	2.1	-0.8	1.5	0.3	0.1	-0.0	-0.5	-0.2	-0.8	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.9	0.3	1.0	-0.8	-0.9	-0.1	-0.2	0.0	0.7	0.6
Taking other prescription medications	0.3	0.4	0.8	-0.7	-0.8	-0.9	0.1	0.6	0.1	-0.5	-0.6	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.1	1.3	-0.0	-0.0	-1.0	-0.2	0.1	0.2	1.5	0.3
Impedance of arm (right)	0.3	1.2	2.4	-1.5	-0.8	1.2	1.0	0.8	1.3	-0.2	-1.2	-1.3
Falls in the last year	0.3	0.4	1.0	0.6	-0.3	-0.1	1.0	1.0	0.3	-0.6	0.6	-0.1
Hair/balding pattern: Pattern 3	0.3	0.4	1.7	-1.2	0.4	-0.4	-0.2	0.0	-0.2	0.5	-1.3	-0.5
Impedance of arm (left)	0.3	1.2	3.0	-1.3	-0.8	1.3	1.7	0.9	1.2	-0.2	-0.9	-0.9
Arm fat mass (right)	0.3	1.2	6.1	-1.4	-0.7	-0.2	-2.5	-0.4	-1.4	0.2	-0.7	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	3.0	-0.0	1.7	-0.7	-0.2	0.3	-0.2	-0.1	-0.2	0.3
High blood pressure (siblings)	0.3	0.4	1.0	-0.1	-1.0	-0.7	0.8	0.6	0.6	-0.8	0.4	-0.4
Medication: Seretide 50 evohaler	0.3	0.3	1.0	-0.4	0.4	-0.5	-0.3	1.0	0.3	-0.7	0.2	-0.5
Alcohol intake frequency.	0.3	0.6	1.5	1.1	1.2	0.2	-0.3	-0.5	-0.3	1.0	-0.6	0.9
Medication: Aspirin	0.3	0.4	1.6	-1.3	0.7	0.5	-0.4	0.2	-0.3	-0.1	-0.8	-0.1
Knee pain experienced in last month	0.3	0.5	2.6	0.7	1.6	0.1	-0.0	0.3	0.0	-0.7	-0.1	-0.6
Illnesses of siblings: Diabetes	0.3	0.4	1.0	-1.0	-0.3	0.8	0.2	-0.2	1.0	-0.4	0.3	-0.4
Ever had bowel cancer screening	0.3	0.3	1.0	0.7	0.4	-1.0	0.7	0.2	0.1	-0.1	0.6	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.9	-0.2	0.8	-1.0	0.7	-0.0	0.5	-0.2	-0.5	-0.4
Asthma (self-reported)	0.3	0.7	1.3	0.7	0.9	-0.7	-0.4	-1.1	-1.1	0.6	0.6	1.1
Medication: Aspirin	0.3	0.3	1.3	-0.8	1.2	0.8	0.2	-0.0	-0.2	0.5	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.2	0.6	0.6	-1.5	-0.1	0.9	0.8	-0.6	0.7	-0.9
Medication: Blood pressure	0.3	0.6	2.5	-0.3	1.4	-0.5	-1.6	0.1	0.2	-0.5	-0.3	-0.0
High cholesterol (Self-reported)	0.3	0.5	1.5	-0.4	0.7	0.3	0.1	0.5	0.3	-1.2	-0.8	-1.0
Illnesses of father: High blood pressure	0.3	0.3	1.1	0.7	0.7	-0.3	-1.1	-0.2	-0.2	-0.2	0.7	0.2
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.3	1.4	-0.3	-0.0	0.9	-0.7	-0.3	1.0	1.5	0.9
Schizophrenia (2018)	0.2	0.5	2.5	0.6	1.6	-0.8	-0.1	0.3	0.3	0.5	-0.0	0.6
Ovarian Cancer	0.2	0.3	0.7	-0.7	0.2	-0.8	-0.0	0.3	-0.1	-0.8	-0.6	-0.6
Age at First Birth	0.2	0.3	1.9	-0.5	0.6	0.2	1.4	0.4	0.1	-0.4	0.1	-0.5
LDL Cholesterol	0.2	0.4	1.4	0.7	1.2	-0.4	0.2	-0.4	-0.2	0.7	0.5	0.6
Triglycerides	0.2	0.3	1.7	0.3	1.3	0.3	-0.6	0.2	0.1	-0.6	0.1	-0.1
Blood White Count	0.2	1.8	5.8	-2.4	2.0	-0.4	-0.6	-1.1	-1.5	0.9	-1.2	0.4
Cardiovascular Disease	0.2	0.6	2.1	-1.4	0.6	0.4	-0.6	-0.3	-0.2	-0.8	-1.1	-0.5
Hypothyroidism (self reported)	0.2	0.5	1.4	1.2	1.1	-0.9	0.3	0.7	0.3	-0.8	0.7	-0.0
Lung FVC	0.2	1.0	3.7	-0.1	-0.4	1.9	-1.8	-0.2	-0.1	0.5	-1.3	0.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.7	-0.2	1.6	0.2	-0.1	-0.2	-0.3	0.2	0.1	0.3
Medication: Metformin	0.2	0.3	1.3	-0.6	0.5	-0.3	0.0	0.4	0.2	0.6	-1.1	0.6
Impedance of leg (right)	0.2	1.1	3.6	-1.6	0.1	1.8	0.4	-0.1	0.2	1.9	-0.3	0.5
Impedance of leg (left)	0.2	0.8	2.6	-1.4	-0.1	1.6	0.2	0.3	0.5	1.4	-0.9	0.1
Mouth/teeth dental problems	0.2	0.3	1.5	0.1	0.6	-0.0	-1.2	0.1	0.3	-0.6	0.2	-0.0
Neuroticism score	0.2	0.3	0.9	-0.8	0.2	-0.4	-0.5	0.0	0.1	-1.0	-0.4	-0.9
Worrier / anxious feelings	0.2	0.4	1.0	-0.9	0.5	1.0	-1.0	0.2	0.5	-0.4	-0.4	-0.5
Standing height	0.2	1.7	3.8	-0.1	-0.1	0.8	1.4	1.8	1.7	-1.9	-0.5	-1.7
Hair/balding pattern: Pattern 4	0.2	0.4	1.4	0.9	0.8	1.2	-0.8	-0.3	0.6	-0.0	-0.0	0.6
Peak expiratory flow (PEF)	0.2	0.4	1.1	1.0	0.9	-0.7	-0.0	-0.3	-0.4	-0.1	1.1	0.5
Loud music exposure frequency	0.2	0.2	1.1	1.0	-0.5	-0.3	0.3	0.0	0.1	-0.3	0.1	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.9	-0.4	0.2	1.0	0.5	0.0	-0.3	-0.3	-0.7	-0.6
Medication: Paracetamol	0.2	0.4	1.4	-0.9	-0.0	-1.2	0.3	0.7	0.0	-0.0	0.7	-0.5
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	-0.7	0.2	-0.5	0.1	0.2	-0.5	0.6	0.8	-0.0
Forced vital capacity (FVC), Best measure	0.2	0.6	1.9	1.1	1.4	0.1	-0.2	0.5	1.1	-0.6	0.3	-0.3
Emphysema/chronic bronchitis	0.2	0.2	0.7	-0.6	0.8	0.6	-0.8	0.3	-0.2	0.2	0.2	0.2
Number of full sisters	0.2	0.3	0.9	0.1	0.6	0.1	-0.9	0.3	0.4	-0.3	0.9	-0.1
Chest pain or discomfort	0.2	0.3	0.8	0.4	0.7	-0.6	-0.2	0.9	0.4	-0.5	-0.2	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	0.8	0.7	-0.5	-0.7	-0.4	-0.4	0.2	0.8	0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	0.8	0.6	-1.0	-0.3	0.2	0.3	-0.7	0.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.8	0.0	0.4	-0.3	0.9	-0.0	-0.7	-0.1	0.9	0.3
Miserableness	0.2	0.3	1.4	0.2	1.1	0.5	-1.2	0.0	0.1	-0.1	0.4	-0.1
Impedance of whole body	0.2	1.3	3.1	-1.7	-0.9	1.8	1.0	0.7	1.0	0.5	-1.2	-0.7
Mean Putamen Volume	0.1	0.1	0.6	-0.2	0.4	-0.4	0.0	-0.1	0.0	-0.4	-0.8	-0.1
Blood Platelet Count	0.1	0.7	3.8	-0.2	1.2	-1.9	-0.4	0.9	-0.1	0.1	0.6	0.1
Heel T-Score	0.1	1.0	2.4	-1.4	-1.5	0.5	-1.4	0.4	0.2	-0.9	-0.2	-1.1
Height	0.1	2.3	7.2	-0.3	0.3	0.6	2.7	1.7	1.6	-1.6	-1.0	-1.8
Neuroticism	0.1	0.2	0.8	-0.9	-0.7	-0.1	-0.3	-0.4	0.1	-0.4	-0.1	-0.3
Hair Pigment	0.1	1.8	4.4	0.4	1.6	-1.2	-1.4	2.1	1.2	-1.7	-0.0	-1.0
Leg fat-free mass (left)	0.1	0.4	1.7	-0.1	-0.5	-0.7	-0.9	0.2	-0.3	-1.3	-0.3	-0.4
Leg predicted mass (left)	0.1	0.4	1.7	-0.2	-0.5	-0.6	-1.0	0.1	-0.4	-1.3	-0.3	-0.5
Waist circumference	0.1	0.5	1.3	-0.6	-0.4	-0.3	-0.8	-0.7	-1.1	0.7	0.0	1.0
Forced vital capacity (FVC)	0.1	0.4	1.2	0.7	0.2	1.1	-0.7	0.2	0.7	-0.2	-0.6	-0.2
Weight	0.1	0.6	2.9	-0.7	-0.8	-0.2	-1.7	-0.1	-0.9	-0.3	-0.5	0.1
Trunk fat-free mass	0.1	0.7	1.9	0.9	0.4	-1.4	-0.3	0.6	0.1	-1.2	1.0	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.6	0.9	1.3	0.1	-0.8	0.2	0.4	-0.1	0.3	-0.2
Pulse rate	0.1	0.2	0.8	0.3	-0.9	-0.2	-0.6	-0.1	0.3	-0.6	0.2	-0.2
Trunk predicted mass	0.1	0.6	1.8	0.9	0.5	-1.3	-0.3	0.6	0.1	-1.1	1.1	-0.1
Birth weight of first child	0.1	0.2	1.4	0.5	1.2	-0.3	-0.0	0.2	-0.1	-0.1	-0.1	0.1
Arm fat-free mass (right)	0.1	0.4	1.0	0.7	-0.0	-0.8	-0.9	0.1	-0.3	-1.0	0.4	0.1
Comparative body size at age 10	0.1	0.4	0.8	0.7	0.2	-0.1	0.4	-0.6	-0.9	0.8	0.5	0.8
Worry too long after embarrassment	0.1	0.1	0.4	0.5	-0.2	-0.3	0.5	-0.6	-0.2	-0.2	-0.3	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.3	-0.4	0.6	0.1	0.3	-0.4	0.0	0.0	0.1	0.3
Arm predicted mass (right)	0.1	0.4	1.0	0.7	-0.0	-0.8	-1.0	0.0	-0.5	-0.8	0.6	0.2
Comparative height size at age 10	0.1	0.6	2.4	-0.6	1.0	1.6	0.6	-0.2	-0.3	-0.3	-0.9	-0.3
Whole body fat-free mass	0.1	0.5	1.6	0.6	-0.0	-1.2	-0.5	0.4	-0.1	-1.3	0.6	-0.2
Leg fat-free mass (right)	0.1	0.6	2.8	0.1	-0.5	-0.8	-0.7	0.4	-0.2	-1.7	-0.4	-0.7
Long-standing illness, disability or infirmity	0.1	0.1	0.3	-0.1	-0.3	0.4	-0.3	0.1	0.1	-0.3	-0.6	-0.5
Mineral and other dietary supplements	0.1	0.1	0.4	-0.1	0.6	-0.1	0.3	-0.3	-0.0	0.6	0.4	0.3
Whole body water mass	0.1	0.4	1.6	0.6	-0.0	-1.0	-0.7	0.3	-0.2	-1.2	0.6	-0.2
Leg predicted mass (right)	0.1	0.5	2.5	0.2	-0.5	-0.8	-0.7	0.4	-0.2	-1.6	-0.5	-0.6
Basal metabolic rate	0.1	0.4	1.1	0.2	-0.2	-0.9	-1.0	0.3	-0.4	-1.1	0.2	-0.2
Arm fat-free mass (left)	0.1	0.5	1.5	0.7	0.1	-1.0	-1.2	0.2	-0.3	-0.6	0.8	0.3
Arm predicted mass (left)	0.1	0.4	1.1	0.5	-0.2	-0.9	-1.1	0.4	-0.2	-0.8	0.7	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.5	2.0	-0.6	0.1	1.4	-0.8	0.7	0.3	-0.4	-0.8	-0.7
Sitting height	0.0	0.1	0.3	-0.2	0.6	0.5	-0.0	-0.2	-0.3	-0.2	-0.3	0.2
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.2	0.1	-0.2	-0.3	-0.1	0.2	-0.0	-0.3	0.4	-0.1

Hub : Genes

LTA4H

Models

Trait associations