[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr15:66,662,107-68,492,262

Best TWAS P=1.75e-11 · Best GWAS P=2.26e-14 conditioned to 8.2e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Thyroid	SMAD3	0.19	0.02	enet	3	0.03	2.3e-03	-7.5	6.7	1.8e-11	-0.64	0.01	0.89	TRUE
1	CommonMind	Brain Pre-frontal Cortex	IQCH	0.13	0.11	bslmm	597	0.10	5.9e-12	5.3	-5.3	1.1e-07	0.06	1.00	0.00	TRUE
3	The Cancer Genome Atlas	Thyroid Carcinoma	SMAD3	0.22	0.12	enet	12	0.11	5.2e-11	-6.6	6.3	2.9e-10	-0.73	0.03	0.97	FALSE