Best TWAS P=1.75e-11 · Best GWAS P=2.26e-14 conditioned to 8.2e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | IQCH | 0.13 | 0.11 | bslmm | 597 | 0.10 | 5.9e-12 | 5.3 | -5.3 | 1.1e-07 | 0.06 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Thyroid | SMAD3 | 0.19 | 0.02 | enet | 3 | 0.03 | 2.3e-03 | -7.5 | 6.7 | 1.8e-11 | -0.64 | 0.01 | 0.89 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | SMAD3 | 0.22 | 0.12 | enet | 12 | 0.11 | 5.2e-11 | -6.6 | 6.3 | 2.9e-10 | -0.73 | 0.03 | 0.97 | FALSE |