Hub : Genes

ITGA1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0590 0.0220 1.7e-03 -0.001 0.022 -0.002 0.019 -0.002 0.56000 0.00084 7.2e-01 0.0021 6.9e-01
2 GTEx Adipose Subcutaneous 0.1100 0.0380 5.2e-04 -0.003 NA 0.018 NA 0.000 0.83000 NA 1.2e-02 NA 3.3e-01
3 GTEx Brain Caudate basal ganglia 0.2440 0.0870 6.2e-03 0.060 NA 0.083 NA 0.076 0.00820 NA 2.2e-03 NA 3.3e-03
4 GTEx Cells Transformed fibroblasts 0.1280 0.0440 2.0e-03 0.045 NA 0.007 NA 0.020 0.00025 NA 8.9e-02 NA 1.1e-02
5 GTEx Lung 0.0966 0.0364 3.0e-03 0.031 NA 0.003 NA 0.008 0.00180 NA 1.9e-01 NA 6.9e-02
6 GTEx Muscle Skeletal 0.1308 0.0374 1.5e-05 0.003 NA 0.051 NA 0.015 0.15000 NA 9.1e-06 NA 1.1e-02
7 GTEx Nerve Tibial 0.1389 0.0455 4.2e-04 0.008 NA 0.021 NA 0.009 0.08600 NA 1.1e-02 NA 6.7e-02
8 GTEx Thyroid 0.1100 0.0360 4.3e-04 0.019 NA 0.006 NA 0.025 0.01200 NA 1.1e-01 NA 4.7e-03
9 GTEx Whole Blood 0.1630 0.0450 1.3e-05 0.018 NA 0.043 NA 0.042 0.00850 NA 7.8e-05 NA 8.4e-05
10 TCGA Breast Invasive Carcinoma 0.0271 0.0113 1.2e-03 0.000 0.012 0.000 NA 0.003 0.40000 0.00100 2.5e-01 NA 7.3e-02
11 TCGA Kidney Renal Clear Cell Carcinoma 0.0511 0.0242 8.5e-03 0.028 0.013 0.003 NA 0.008 0.00034 0.01100 1.4e-01 NA 4.1e-02
12 TCGA Brain Lower Grade Glioma 0.0400 0.0180 7.8e-03 0.001 0.015 0.008 NA -0.001 0.25000 0.00690 3.5e-02 NA 5.1e-01
13 TCGA Pheochromocytoma and Paraganglioma 0.2180 0.0700 6.5e-04 0.018 0.072 0.058 NA 0.019 0.06100 0.00081 2.5e-03 NA 5.7e-02
14 TCGA Thyroid Carcinoma 0.0630 0.0290 4.9e-03 0.018 0.012 0.023 NA 0.014 0.00680 0.02000 2.3e-03 NA 1.5e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.6 2.3 -0.3 0.5 -0.1 1.5 -0.9 1.0 0.6 0.5 0.7 -0.5 -1.1 0.9 -0.1 0.1
Bipolar Disorder or Schizophrenia 0.2 0.4 1.2 0.6 -1.1 -0.9 0.6 -0.3 -0.3 0.1 -0.1 0.4 0.2 -1.1 1.0 0.1 0.1
Depressed Affect (Nagel 2018) 0.5 1.0 3.3 0.2 1.3 -0.7 -0.1 1.0 1.5 0.6 1.8 1.6 -1.3 0.7 0.3 0.2 0.6
Depression (Nagel 2018) 0.5 0.8 4.6 2.1 -0.7 -1.0 -0.0 -0.8 -0.2 -1.1 -1.0 -0.5 0.1 0.4 1.3 0.2 0.7
Intelligence (Savage-Jansen 2018) 0.4 1.2 3.4 -0.7 -0.5 1.3 -1.1 -0.5 -1.2 -1.1 -1.3 -0.9 1.6 0.2 -0.4 1.8 1.3
Neuroticism (Nagel 2018) 0.4 1.0 4.6 -0.3 0.7 -0.4 0.5 1.7 0.9 -0.2 1.3 2.1 -0.9 0.8 -0.3 0.8 1.1
Schizophrenia (2018) 0.3 0.6 3.5 0.9 -1.9 -1.1 -0.4 0.3 -1.1 -0.5 -0.5 -0.0 0.7 -0.5 0.6 0.2 -0.1
Schizophrenia vs Biploar Disorder 0.5 0.7 4.0 1.0 0.5 0.7 -0.4 1.7 0.1 -0.3 0.3 -0.1 -0.6 2.0 -0.2 -0.8 0.3
Worry (Nagel 2018) 0.3 0.7 2.5 -1.3 0.3 -0.6 0.9 1.1 0.1 -0.4 0.3 1.6 0.0 0.3 -1.2 0.9 0.7
Alzheimer’s Disease (in mother) 0.6 0.7 1.7 0.7 -1.3 0.4 0.6 1.1 -1.0 -1.0 -0.3 -1.3 0.7 -1.0 -0.9 0.2 0.0
Alzheimer’s Disease (in father) 0.5 0.5 2.3 0.1 -0.8 0.6 -0.1 0.2 -1.5 -0.5 0.3 1.3 1.2 -0.3 -0.4 -0.0 0.7
Alzheimer’s Disease (including proxy) 0.8 1.1 3.4 1.1 -1.4 1.4 0.9 1.3 -1.9 -0.8 0.2 0.5 0.2 -1.6 -0.9 -0.5 -0.3
Crohns Disease (2017) 0.3 0.7 4.2 -0.3 0.1 0.5 -0.8 -1.4 0.2 -0.7 -0.7 -0.1 2.0 0.2 0.5 0.6 0.7
Irritable Bowel Disease (IBD) 0.4 0.9 4.5 -0.4 -0.2 -0.1 -0.8 -2.1 0.1 -0.8 -1.5 -0.1 1.8 -0.0 0.3 1.0 0.0
Ulcerative Colitis (UC) 0.4 0.7 2.8 -0.4 -0.1 -0.6 -0.2 -1.7 0.3 -0.8 -1.6 0.1 1.2 -0.4 0.5 0.9 -0.3
Major Depression (MDD) 0.6 0.7 4.9 0.1 1.2 -0.4 -0.5 -0.1 2.2 0.3 -1.1 -0.4 0.6 -0.5 1.2 0.4 -0.2
Reaction Time 0.6 1.2 4.2 0.4 0.1 0.7 1.0 2.0 -1.0 1.5 0.6 1.6 -1.7 -0.1 -1.1 -0.7 0.0
Verbal and Numeric Reasoning (VNR) 0.6 1.4 4.0 -1.9 -0.1 2.0 -1.2 -0.7 -1.1 -0.8 -0.4 -0.9 1.3 -0.2 -1.8 1.4 0.3
Breast Cancer 0.6 1.4 3.6 0.1 -1.1 -0.6 1.8 1.3 -1.7 0.7 -0.2 1.0 -1.2 1.5 -1.4 0.2 1.9
Ovarian Cancer 0.4 0.5 2.6 0.9 0.7 0.6 -0.7 0.6 -1.2 -0.7 -0.2 1.6 0.0 0.0 -0.4 -0.2 -0.1
Prostate Cancer 1.0 1.5 7.2 0.6 1.3 0.4 -2.0 0.8 -0.1 1.0 0.1 -0.5 -1.3 2.7 -0.3 -0.9 1.6
Age at First Birth 0.5 0.7 2.1 0.2 1.4 0.3 -1.0 -0.2 0.5 -0.1 -0.1 -1.2 -1.4 -0.1 1.0 -0.5 -0.9
Bipolar Disorder (2011) 0.8 0.8 4.5 0.2 1.2 0.1 0.3 0.5 1.1 2.1 0.6 0.7 0.2 -0.7 0.1 1.2 -1.0
Body Mass Index (BMI) (2010) 0.7 0.9 2.2 0.5 -0.6 0.1 0.2 -1.3 -1.0 -0.2 -1.2 0.9 1.5 -1.0 -1.2 1.5 -0.8
Coronary Artery Disease (CAD) 0.7 0.9 5.7 -0.2 1.2 -0.2 0.7 -0.9 0.2 1.0 -0.5 2.4 0.7 -1.0 -0.1 0.8 -0.6
Crohns Disease (2012) 0.5 0.8 3.2 -0.3 1.8 0.1 0.5 -1.3 -0.0 0.1 -1.0 1.7 1.1 0.2 0.1 -0.0 0.4
Mean Putamen Volume 0.4 0.5 2.7 0.2 0.2 0.9 -0.1 0.0 1.7 1.3 0.4 0.7 -0.1 -0.2 0.0 -0.3 -0.1
Fasting Glucose 1.3 1.6 4.8 -2.1 -0.4 0.0 1.4 -0.8 -1.0 0.5 -0.2 1.5 1.8 -0.8 -2.2 1.6 0.1
HbA1C 0.9 1.0 4.3 -1.3 -2.1 0.2 1.4 0.1 -1.3 -0.3 -0.7 1.3 -0.1 -1.4 -0.7 -0.2 -0.3
HDL Cholesterol 0.4 0.7 2.2 -1.3 0.2 0.2 -0.2 1.4 0.9 1.5 0.6 0.0 -1.2 -0.0 -0.5 -0.4 -0.7
LDL Cholesterol 0.7 1.1 3.8 -0.3 1.1 1.4 -1.0 -0.2 1.7 1.9 0.8 -1.0 -1.0 -0.3 1.1 -0.4 -0.4
Lupus 0.9 1.3 3.9 -0.6 0.2 1.0 -1.4 0.8 0.5 1.8 2.0 -1.4 -1.4 0.4 -1.3 -1.1 -0.7
Neuroticism (2016) 0.8 1.1 4.5 0.3 1.1 0.4 0.0 0.1 2.1 0.6 1.8 1.8 -0.0 0.6 0.8 -1.1 1.0
Primary Biliary Cirrhosis 4.4 6.2 12.0 -0.7 -3.5 -1.8 2.5 -2.8 -3.4 -3.2 -3.2 1.3 2.6 -0.7 -1.4 3.2 1.8
Rheumatoid Arthritis 1.0 1.3 3.9 -0.4 -1.6 2.0 1.3 -0.9 -1.0 -1.0 -0.2 1.0 1.7 -0.0 -1.2 0.9 -1.2
Schizophrenia (2014) 0.2 0.5 2.7 0.8 -1.0 -1.6 0.0 0.3 0.3 0.3 0.2 -0.4 -0.9 0.7 0.9 -0.4 -0.1
Triglycerides 1.1 1.7 4.4 2.0 -0.5 -0.5 -0.6 -1.8 -0.7 -1.2 -2.1 -1.0 1.1 0.6 1.8 0.2 2.0
Type 2 Diabetes (T2D) (2012) 2.0 2.3 7.8 -0.8 -1.7 -2.8 2.2 -0.8 -0.6 -0.6 -0.4 1.1 1.8 -2.6 -0.2 1.3 -0.9
Ulcerative Colitis 1.4 2.0 7.8 -0.0 -0.9 -0.7 -0.2 -2.6 0.4 -1.1 -2.2 0.9 2.8 0.1 1.5 0.8 1.6
Blood Eosinophil Count 0.3 2.2 8.1 -0.7 -1.8 -0.6 -0.6 -0.8 -0.4 -2.0 -1.5 -0.8 2.9 -2.1 1.3 0.8 1.9
Blood Platelet Count 0.3 2.9 11.2 0.6 0.3 -1.4 -0.4 3.3 1.6 -0.4 3.4 -0.8 -3.2 0.4 -1.3 -0.2 -1.1
Blood Red Count 0.5 4.5 16.7 4.1 -0.4 -1.2 -1.1 -2.2 -0.7 -1.0 -1.5 -3.9 0.1 2.3 1.6 1.1 3.2
Blood White Count 0.9 6.9 16.7 -3.3 1.0 0.6 2.7 3.4 1.1 1.5 2.8 3.1 -2.5 -4.1 -2.6 -0.3 -3.7
Heel T-Score 0.9 7.4 29.3 -4.1 1.5 4.3 0.5 -0.2 5.4 4.0 2.4 2.8 -0.4 -1.0 0.1 0.7 -2.2
BMI 0.3 1.5 4.4 1.6 0.5 -1.2 0.8 1.2 1.8 2.0 1.1 -1.0 -2.1 -0.1 -0.8 0.3 0.4
Height 0.2 4.7 16.9 -0.6 1.0 3.0 -4.1 0.7 2.6 2.2 2.8 -2.2 0.1 0.5 -0.0 -3.5 -0.7
Waist Hip Ratio (WHR) 0.3 1.4 3.8 0.9 0.4 -0.9 0.6 1.9 1.6 0.4 1.7 0.8 -1.8 1.5 1.3 -0.6 0.1
Systolic Blood Pressure 0.4 2.1 5.4 1.0 -2.0 -2.3 1.9 -0.4 -0.6 0.7 -0.6 0.5 0.2 2.0 1.1 2.2 1.7
Smoking Status 0.5 1.3 7.3 0.3 -1.6 -0.9 -0.2 0.0 -0.3 -0.7 -0.2 0.5 1.5 1.9 -0.3 2.7 0.9
Allergy or Eczema 0.2 0.6 4.0 -0.2 0.9 -0.1 -0.2 -1.4 0.7 0.4 -0.2 0.2 2.0 -0.7 0.2 0.9 -0.2
Cardiovascular Disease 0.7 2.4 7.0 -0.6 -2.5 -1.9 1.8 -0.7 -0.3 -0.7 -0.9 1.2 1.5 -2.6 -1.2 2.4 -0.3
Hypothyroidism (self reported) 0.9 2.0 6.1 1.9 1.4 -1.0 -0.5 0.2 1.9 2.5 2.0 -0.3 -1.2 -0.1 1.1 -1.7 1.2
Respiratory disease 2.0 4.4 18.8 0.7 2.0 -1.7 -0.9 1.3 4.3 2.9 2.7 -0.5 -2.6 -0.3 2.0 -2.4 0.1
Type 2 Diabetes (T2D) (2018) 1.3 2.5 9.7 -1.3 -0.8 -0.8 -0.2 -0.9 1.8 1.1 0.3 1.4 2.9 -3.1 1.9 1.3 -0.9
Lung FEV1/FVC ratio 4.9 24.8 64.8 1.8 -8.1 1.9 1.9 -7.0 -7.9 -1.5 -6.8 -2.3 6.6 -6.8 2.9 0.1 3.0
Lung FVC 1.6 8.2 17.9 -0.3 -2.3 4.2 2.0 -3.1 -4.1 -2.3 -2.8 0.4 3.9 2.7 -2.8 2.9 3.0
Neuroticism 0.3 0.7 2.6 -0.2 1.0 0.1 -0.6 1.6 1.1 -0.1 1.6 1.1 -0.6 0.7 -0.1 0.2 0.8
Chronotype (morning person) 0.6 1.3 12.1 -0.1 -1.4 0.6 0.7 0.6 -3.5 -0.1 -0.3 -0.4 0.0 -1.1 -1.4 -0.1 0.6
Hair Pigment 0.1 2.7 10.1 3.2 0.2 -1.2 0.6 -1.6 -1.7 -2.4 -2.1 -2.5 -0.1 -1.0 0.9 -0.3 1.5
Tanning 0.2 2.0 10.0 -0.7 -3.2 -0.9 0.5 -1.8 -0.8 -1.1 -1.2 0.6 2.1 0.4 -0.3 1.6 1.3
Hand grip strength (left) 0.9 2.4 12.7 -2.4 -0.4 3.6 -0.8 -0.2 -1.3 -0.3 -0.1 1.6 0.8 0.7 -2.8 -0.2 -0.4
Number of treatments/medications taken 0.5 0.9 3.2 0.5 -0.2 -1.2 0.5 -1.0 1.8 -0.0 -0.2 -0.4 0.4 -0.8 1.6 1.1 1.3
Average weekly spirits intake 1.9 2.3 7.5 -1.0 1.5 0.7 -1.0 0.6 2.3 1.8 2.3 1.1 -0.6 -1.1 0.7 -2.7 -1.8
Sensitivity / hurt feelings 0.4 0.7 2.3 -0.3 -0.1 0.0 0.7 1.5 0.5 -0.0 0.8 0.9 -1.4 -0.9 0.4 -1.4 -0.5
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.6 0.5 -0.4 -0.2 -0.8 -1.2 0.8 -0.2 -0.0 0.5 1.2 -1.3 0.9 -0.2 0.6
Hearing difficulty/problems: Yes 0.8 1.2 3.5 1.0 1.4 -1.9 -1.4 -0.3 1.6 0.5 0.2 -1.7 -0.6 0.3 1.3 -0.7 0.1
Relative age of first facial hair 0.4 0.8 3.3 0.3 -1.0 1.8 1.0 1.2 -0.6 -0.8 1.0 0.6 -0.3 0.8 0.4 -0.9 -0.1
Other serious medical condition/disability diagnosed by doctor 1.2 1.5 5.4 -0.5 2.2 0.7 -1.3 0.0 2.3 0.7 0.9 -2.1 -0.9 0.5 1.1 -0.4 -0.0
Ever used hormone-replacement therapy (HRT) 1.6 2.0 6.5 2.6 -1.4 -0.9 -1.2 -1.4 -0.1 -0.7 -1.4 -0.8 1.9 1.2 1.6 1.2 1.7
Ever had hysterectomy (womb removed) 0.7 0.8 2.6 0.3 -1.0 -0.4 -1.2 -1.4 -0.1 -1.0 -0.6 -1.6 0.4 0.2 1.4 -0.3 -0.6
Systolic blood pressure, automated reading 0.6 1.8 4.9 0.9 -1.2 -1.7 2.1 -0.5 -0.6 1.1 -1.1 0.0 0.6 2.2 0.9 2.2 1.5
Eye problems/disorders: Diabetes related eye disease 0.6 0.6 3.7 0.2 -1.4 -0.1 0.8 1.0 0.3 -0.0 -0.3 -0.3 -0.4 -1.9 0.4 -0.3 0.6
Angina 0.8 1.1 6.1 0.8 -1.0 0.8 2.5 0.4 -0.2 0.2 -0.8 1.9 0.2 -1.2 -0.1 0.7 -0.8
Medication for hormone replacement therapy 2.8 3.2 10.3 0.9 -1.5 -0.3 1.1 -3.2 -1.4 -3.0 -2.2 0.6 2.5 0.4 2.1 0.8 1.3
Vitamin and mineral supplements 0.7 0.9 3.4 0.4 1.1 0.2 -1.4 0.8 0.5 1.4 0.8 -0.2 -0.9 -0.7 0.9 -1.9 -0.9
Supplements: Zinc 0.6 0.7 4.1 0.1 0.3 -0.9 0.8 -0.8 -0.8 -0.1 -0.4 -0.6 -0.4 2.0 -0.8 0.8 0.7
Medication: Co-codamol 1.4 1.6 3.6 1.7 -1.7 -0.0 -0.7 1.5 -1.6 -1.6 -0.7 -1.3 0.7 -1.9 -0.1 -0.8 -1.4
Medication: Metformin 1.2 1.6 6.5 -0.1 -1.4 -0.1 -1.0 -0.9 1.2 -0.5 -1.5 -0.0 2.1 -2.6 1.3 1.6 0.2
Diabetes (father) 0.6 0.7 2.6 -0.9 0.1 0.2 -0.2 -1.1 0.2 -0.8 0.2 1.6 1.1 -0.6 1.2 0.6 -1.2
Diabetes (mother) 0.5 0.7 3.5 -1.2 -0.8 0.5 -0.1 1.4 0.3 0.2 0.2 0.6 0.3 -1.9 -0.3 0.2 -1.1
Severe depression (siblings) 0.6 0.6 2.0 -0.5 0.7 -0.1 0.4 -1.3 -0.6 -0.4 -0.5 1.3 1.4 -1.2 0.5 0.1 0.0
Pack years adult smoking proportion 0.4 0.6 2.6 0.2 -0.3 1.1 -0.9 -0.3 1.6 0.4 0.8 -0.5 0.2 0.5 1.2 -0.7 -0.4
Impedance of leg (right) 0.3 1.6 6.0 2.4 0.4 -2.0 -1.5 -0.4 0.9 -0.8 -0.3 -1.1 -0.5 0.4 2.4 -0.3 1.1
Leg fat-free mass (left) 0.2 0.9 3.6 -1.0 0.4 0.4 -1.0 0.7 1.2 1.9 1.6 -0.4 -0.4 -0.1 -1.4 -0.1 -0.5
Trunk fat percentage 0.6 2.3 11.6 2.2 0.7 -1.6 -0.7 0.6 3.4 1.1 1.5 -1.9 -1.2 -0.3 1.7 -0.2 0.1
Hand grip strength (right) 0.9 2.5 11.3 -2.3 -1.2 2.7 -0.0 -0.0 -1.9 -0.2 0.4 1.3 1.4 1.3 -3.4 0.6 0.0
Townsend deprivation index at recruitment 0.4 0.6 2.1 0.2 -0.9 -1.0 -0.6 -0.1 0.4 -0.7 -0.6 -1.5 -0.3 -0.1 1.1 -0.9 0.5
Current tobacco smoking 0.4 0.6 2.6 -0.6 0.1 0.2 -1.3 1.0 0.7 -0.5 0.2 0.9 0.4 -0.7 -0.5 0.5 -1.6
Average weekly fortified wine intake 0.9 1.0 3.1 1.8 0.4 -0.9 -1.6 0.5 -0.6 0.4 -0.7 -1.1 0.6 1.1 -1.0 1.2 -1.0
Maternal smoking around birth 1.0 1.4 5.5 -2.0 -1.4 0.4 0.1 -0.1 0.2 -0.6 -0.0 0.8 1.5 -1.1 -1.9 2.4 -0.6
Fed-up feelings 1.1 2.1 7.4 0.7 1.9 -0.6 -0.4 1.1 2.0 1.6 2.7 1.1 -2.5 0.2 0.3 -1.4 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 5.2 2.3 -0.5 -1.1 -0.2 0.7 1.6 -0.7 -0.1 -0.4 -1.3 1.1 1.2 -0.9 -0.3
Relative age voice broke 0.7 1.1 7.3 -1.3 -0.1 2.7 0.5 1.7 -0.1 -0.5 0.9 0.2 -0.3 1.0 0.0 -0.7 -0.5
Taking other prescription medications 0.6 1.0 3.6 0.8 0.2 -1.2 0.2 0.1 1.8 0.7 1.7 -0.3 -1.9 -0.4 1.0 -0.2 -0.2
Age when periods started (menarche) 1.0 2.5 14.1 -1.1 0.2 1.0 -3.8 -1.0 1.9 -0.6 -0.4 -3.2 0.8 1.0 0.9 -0.5 0.8
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 4.9 2.2 -1.0 -0.8 -1.2 -0.9 -0.7 -1.7 -0.3 -1.1 0.9 0.4 1.2 0.8 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 1.6 3.6 9.5 -1.9 2.9 3.1 0.6 0.9 2.4 2.5 1.6 2.0 -1.4 -0.2 0.9 -1.4 -2.2
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 6.0 1.1 -1.1 0.2 -0.3 -0.3 -2.0 -1.7 -2.4 -1.3 0.0 -0.2 -0.7 0.3 0.4
Qualifications: CSEs or equivalent 1.3 1.7 5.3 -1.5 -1.1 0.2 0.3 -1.3 -2.3 -1.8 -0.8 0.8 1.9 -2.0 0.1 -0.5 0.3
Serious illness, injury or assault to yourself 0.6 0.8 2.7 -0.0 1.2 -0.3 -1.6 0.8 1.1 1.6 0.9 -0.6 0.0 0.5 0.4 0.0 -0.6
High blood pressure 1.2 3.2 8.9 -0.2 -2.8 -1.7 2.0 -2.3 -0.3 -1.4 -1.6 1.3 2.3 -1.5 -0.6 3.0 1.1
Hayfever, allergic rhinitis or eczema 0.4 0.8 1.6 -0.5 1.3 -0.0 0.4 -0.6 0.9 0.6 0.3 1.2 1.1 -1.2 -0.7 1.2 -1.0
Multivitamins +/- minerals 0.4 0.5 2.0 -0.6 -0.2 0.2 0.4 -0.2 -0.9 -1.1 0.0 -0.5 0.4 0.3 -1.4 1.4 0.2
Stomach or abdominal pain in last month 0.3 0.3 1.2 -0.6 0.6 -1.1 0.7 0.5 0.6 -0.6 0.0 0.7 -0.7 0.3 0.2 -0.3 0.7
Supplements: Glucosamine 0.8 1.0 4.7 -0.4 -1.2 -1.0 0.8 -1.6 0.3 -1.0 -0.9 -0.3 0.8 0.1 0.1 2.2 0.7
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 3.1 0.9 1.2 0.9 -0.4 -1.1 1.2 0.6 -0.5 0.2 0.5 1.8 0.9 0.4 0.8
Medication: Atenolol 1.8 2.2 5.4 1.1 -1.7 -1.1 1.5 -2.0 -1.9 -2.3 -2.3 -0.7 0.9 -1.7 0.9 0.9 0.2
Medication: Levothyroxine sodium 0.6 0.9 3.6 0.9 0.6 -1.9 0.3 -0.9 0.7 1.4 0.4 -0.1 0.0 0.1 1.0 0.3 1.9
Sitting height 0.2 1.6 9.9 -0.5 -0.4 1.4 -1.3 0.2 0.2 3.1 1.8 -0.9 0.1 0.1 -2.2 0.0 -0.1
Chronic bronchitis/emphysema (father) 0.9 1.1 2.8 -0.7 0.1 -1.7 0.5 1.1 1.7 0.9 0.7 0.9 0.1 -1.4 0.2 1.1 -1.6
High blood pressure (mother) 1.0 1.4 5.1 -0.3 -0.1 1.0 1.2 -1.4 -1.6 -1.7 -1.7 0.8 0.7 0.6 -0.5 2.3 0.5
Body mass index (BMI) 0.2 0.8 2.4 0.6 0.3 -0.6 1.5 0.0 1.6 1.4 1.1 0.8 -0.9 -0.7 -0.4 0.6 0.2
Impedance of leg (left) 0.3 1.4 8.0 2.2 0.6 -1.1 -1.4 -0.3 1.1 -0.1 -0.2 -0.9 -0.2 0.1 2.8 -0.5 0.9
Leg predicted mass (left) 0.2 0.8 3.5 -1.0 0.3 0.3 -1.0 0.6 1.1 1.9 1.5 -0.4 -0.4 -0.1 -1.4 -0.2 -0.4
Trunk fat mass 0.4 1.7 10.4 1.5 0.7 -1.1 -0.7 0.6 3.2 1.5 1.7 -1.4 -1.1 -0.4 0.9 -0.2 0.1
Waist circumference 0.3 1.1 5.0 1.2 0.8 -0.9 0.7 0.3 2.2 1.5 1.1 -0.1 -1.5 0.0 0.5 0.2 0.6
Number of incorrect matches in round 0.6 1.0 4.1 2.0 -1.2 -1.8 -0.5 0.1 -1.3 -0.2 -0.6 -1.2 -0.6 0.3 0.1 -0.4 0.9
Past tobacco smoking 0.6 1.0 4.8 -0.6 2.2 1.6 -0.8 -0.0 0.7 -0.6 -0.6 -0.0 -0.2 -0.5 0.9 -1.7 -1.0
Alcohol usually taken with meals 0.7 1.1 4.0 0.2 2.0 1.8 -1.3 -0.6 0.7 0.1 0.1 0.7 1.9 1.1 -0.5 0.6 0.1
Nervous feelings 0.4 0.7 2.0 -0.4 0.9 -0.1 0.6 1.1 0.9 0.6 0.7 1.4 -1.2 1.2 0.2 -1.0 0.1
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 6.6 -1.2 1.0 0.4 -0.4 -0.9 1.2 -0.1 0.7 2.6 2.1 -0.5 0.5 0.5 -0.1
Hearing difficulty/problems with background noise 1.2 1.9 7.5 1.5 0.2 -1.9 -2.6 -0.7 1.0 -0.2 -0.8 -1.4 1.4 -0.7 2.7 -0.6 0.5
Hair/balding pattern: Pattern 2 1.3 1.6 5.3 0.0 -0.9 -1.0 0.8 -1.4 -1.3 -2.3 -1.9 0.6 1.5 -0.1 1.2 1.2 1.3
Had menopause 0.8 1.0 2.6 0.7 0.0 1.5 -1.4 -0.4 1.6 0.8 0.7 -1.4 1.0 0.2 0.7 -1.3 -0.8
Had other major operations 0.4 0.5 1.2 -0.4 1.1 0.7 -0.5 1.1 0.6 0.9 0.4 -0.5 0.5 -1.1 0.6 0.1 -0.4
Forced vital capacity (FVC) 0.9 3.3 9.4 -0.9 -0.8 1.1 -0.6 -2.2 -2.8 -1.2 -0.8 -1.2 1.9 2.2 -3.1 2.2 1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.1 7.0 -1.3 2.5 2.6 0.2 0.5 2.2 2.0 1.3 1.0 -0.9 0.3 0.3 -0.0 -1.3
Ever unenthusiastic/disinterested for a whole week 1.3 1.6 5.5 0.9 1.0 1.4 -0.5 2.4 1.2 1.2 1.1 -0.9 -1.7 1.1 -0.5 -1.4 -0.9
Qualifications: None of the above 1.0 2.1 6.8 2.2 -2.1 -1.0 0.1 -1.2 -0.3 -1.5 -2.6 0.7 0.6 -0.8 2.2 0.4 1.4
Financial difficulties in last 2 years 0.4 0.5 0.9 -0.8 0.5 -0.9 0.7 0.9 0.5 0.0 0.9 -0.3 -0.6 -0.4 -0.7 -0.8 0.9
Mouth/teeth dental problems 0.7 1.1 3.2 0.0 -0.9 -1.1 1.5 -1.0 -1.5 -1.5 -0.8 0.3 -0.6 1.0 0.1 1.8 0.8
Heart attack 1.4 1.8 7.2 1.8 -0.5 0.4 -0.4 -0.4 0.4 2.3 0.6 -0.7 -1.7 -0.2 2.2 -2.7 0.2
Allergy 0.3 0.7 2.8 0.4 -1.1 -0.1 0.7 -0.3 -1.7 -1.3 -0.9 -0.6 -0.4 0.9 0.2 -0.2 1.0
Pain all over the body in last month 0.6 0.6 2.2 -0.6 0.6 -0.4 -0.8 0.6 -0.2 1.2 0.9 -0.4 0.3 -1.5 -0.2 -0.3 -1.2
Diabetes (self-reported) 2.6 4.0 17.8 0.4 -2.6 -0.2 -0.8 -1.7 1.3 -1.5 -1.7 1.2 4.2 -2.9 2.2 2.5 0.7
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 2.5 -1.2 1.1 0.6 -0.1 0.2 0.5 1.6 1.3 0.1 0.8 -0.7 -0.8 0.3 -0.7
Medication: Ramipril 0.4 0.5 2.4 1.6 -0.0 0.3 0.8 0.0 0.4 0.8 1.0 1.4 -0.1 0.4 -0.4 0.0 0.7
Medication: Simvastatin 1.2 1.8 11.8 -0.4 -1.5 -0.6 1.8 -0.3 -0.8 0.4 -0.7 1.8 0.8 -3.4 -0.1 1.5 -0.3
Fluid intelligence score 0.3 0.6 3.0 -1.6 0.6 0.3 -0.8 0.1 -0.9 -0.6 0.4 -0.3 0.3 0.2 -1.7 0.9 0.2
Illnesses of siblings 1.7 2.5 6.2 -0.2 1.5 -0.7 -1.9 1.8 1.2 2.3 1.3 1.3 -1.9 -1.1 0.4 -2.5 -1.7
Neuroticism score 0.7 1.4 4.6 -0.8 1.2 0.7 0.0 2.1 1.3 0.7 2.0 1.8 -1.3 -0.4 -0.4 -1.0 -0.3
Weight 0.2 1.0 5.3 0.2 0.8 0.1 -0.6 0.3 2.3 1.9 1.7 -0.3 -0.6 -0.2 -0.3 -0.2 0.1
Impedance of arm (right) 0.9 4.3 13.6 3.2 -0.7 -3.4 -2.3 -0.0 0.3 -2.1 -1.7 -3.7 -0.1 1.0 2.8 -0.6 1.4
Arm fat percentage (right) 0.4 1.5 6.8 2.6 -0.5 -2.3 1.0 -0.2 1.7 -0.2 -0.1 -0.8 -1.0 -0.4 1.3 0.4 0.9
Trunk fat-free mass 0.2 1.2 4.3 -1.5 0.5 2.1 -0.8 -0.1 0.4 1.7 1.0 0.6 0.2 0.5 -2.0 0.1 0.4
Hip circumference 0.2 1.0 5.7 0.5 1.3 -0.1 -0.2 0.2 1.7 2.4 1.1 -0.4 -1.1 -0.2 -0.6 0.1 0.0
Time employed in main current job 1.4 1.6 5.9 1.9 0.3 2.4 -1.6 0.0 0.6 -1.1 -1.6 -1.1 0.1 0.7 0.2 -1.4 1.6
Alcohol intake versus 10 years previously 0.5 0.8 1.9 -0.4 0.8 -1.2 -0.1 -1.2 0.2 0.9 1.1 -0.7 -0.5 0.9 -0.8 1.1 1.4
Father’s age at death 0.6 0.8 4.0 0.5 0.6 1.0 -2.0 0.1 -0.1 -0.2 -0.2 0.2 1.6 1.1 1.3 -0.5 0.1
Worrier / anxious feelings 0.8 1.6 5.3 -0.0 2.2 0.5 0.2 2.3 0.9 0.7 1.3 0.6 -1.7 -0.2 0.4 -2.1 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 8.1 -0.4 0.5 -0.4 -0.4 0.3 2.9 0.0 1.4 1.8 -0.2 0.1 1.0 -0.0 0.5
Falls in the last year 0.6 0.7 2.3 -0.9 -0.8 -0.5 0.7 -1.2 0.2 -1.5 -0.2 -0.5 1.4 -1.0 1.0 0.6 -0.1
Hair/balding pattern: Pattern 3 1.2 1.7 7.1 0.3 0.8 1.5 1.1 1.4 -0.3 2.7 0.9 0.5 -1.6 -1.0 -0.4 -1.2 -2.1
Number of live births 0.5 0.7 1.7 1.3 -1.1 -1.0 -0.1 0.1 -0.3 0.5 -1.0 -0.1 -1.1 1.0 -1.2 0.9 0.4
Forced expiratory volume in 1-second (FEV1) 1.9 6.5 26.0 0.1 -3.0 1.0 0.2 -3.8 -5.1 -1.4 -2.6 -1.5 3.2 0.7 -2.2 2.1 3.1
Pulse rate 1.3 2.2 7.9 -0.3 -1.6 -0.3 2.6 0.0 -1.6 -1.0 0.1 2.2 0.7 -2.8 -1.1 -0.2 -1.5
Happiness 0.5 0.6 4.6 0.5 -0.4 1.5 -0.3 0.5 -0.6 0.1 0.4 0.4 -0.3 -0.7 -2.1 -0.2 -0.5
Noisy workplace 1.0 1.3 7.7 0.5 1.7 0.6 -1.2 -0.7 2.8 -0.1 0.7 -0.5 -0.4 0.5 1.7 -0.8 0.1
Qualifications: A levels/AS levels or equivalent 0.4 0.9 5.3 -1.6 2.3 1.0 -0.5 -0.2 -0.3 0.4 -0.4 -0.3 0.6 0.1 0.4 -0.6 -1.4
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 4.7 -0.2 -0.1 -0.9 -1.2 0.0 -0.4 -0.3 -1.0 -2.2 0.2 0.5 0.2 0.4 0.7
Mouth/teeth dental problems: Dentures 0.7 1.2 5.7 -0.4 0.6 0.4 -1.9 1.1 2.4 1.0 0.0 -1.2 0.7 -1.0 -0.2 0.6 -0.9
Asthma 0.9 1.8 7.6 -0.2 1.1 -2.1 -0.9 1.0 2.8 1.9 1.2 -0.5 -1.2 -1.0 1.4 -0.6 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 2.2 -0.2 -0.4 -0.9 0.9 -1.1 -0.4 -1.4 -0.1 0.1 1.4 1.5 0.0 0.7 0.9
Medication: Cholesterol lowering 1.2 1.9 11.9 -1.6 -1.7 0.9 1.9 0.7 -0.8 0.2 0.1 1.6 0.7 -3.5 -0.3 0.3 -0.6
Depression (self-reported) 0.3 0.3 1.3 -0.0 0.5 -0.0 -0.6 0.3 1.1 -0.6 0.1 -0.3 0.3 -0.2 1.0 -0.5 -0.7
Medication: Lansoprazole 1.4 1.6 7.0 -1.6 0.2 2.0 2.6 -0.1 0.9 0.4 1.3 2.2 -0.7 0.7 -0.6 -0.2 0.2
Prospective memory result 0.5 0.6 1.7 1.1 0.2 1.2 0.5 0.2 -0.4 0.8 -0.9 -0.4 0.4 -0.8 0.8 -0.8 -1.3
Lung cancer (father) 0.8 1.0 2.4 1.5 -0.7 0.1 1.5 -1.3 -0.1 -1.3 -1.4 -0.2 0.2 -0.1 0.7 1.3 1.0
Illnesses of mother 0.6 0.7 1.9 0.1 0.3 -1.1 -1.3 0.0 -0.9 1.1 -0.0 0.3 -0.5 -1.3 -0.5 -1.4 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 1.5 4.8 19.9 -1.1 -2.2 2.2 0.7 -3.4 -4.5 -0.9 -1.7 -1.2 2.9 0.1 -2.1 1.0 2.3
Pulse wave Arterial Stiffness index 0.7 0.9 5.4 -0.3 -0.6 0.4 -0.2 -0.4 -0.7 -2.3 -1.1 -0.2 1.7 -0.7 0.0 0.2 -0.5
Impedance of arm (left) 0.7 3.1 11.6 2.9 -0.7 -3.1 -2.0 0.4 0.4 -1.8 -0.5 -3.4 -0.3 0.7 2.2 -0.6 0.9
Arm fat mass (right) 0.2 0.8 4.1 1.4 0.0 -1.1 0.5 0.1 2.0 0.9 0.9 -0.3 -1.0 -0.4 0.2 0.2 0.3
Trunk predicted mass 0.2 1.1 4.3 -1.5 0.5 2.0 -0.7 -0.1 0.3 1.7 0.9 0.6 0.2 0.5 -2.1 0.1 0.4
Standing height 0.3 3.0 18.8 -0.9 0.9 1.6 -4.3 0.3 1.8 1.6 1.7 -2.5 0.5 1.0 -0.2 -1.8 0.2
Length of working week for main job 1.0 1.1 3.5 0.2 0.5 1.9 -1.1 0.4 1.5 0.3 -0.6 1.8 1.1 -0.9 1.4 -0.4 -0.7
Exposure to tobacco smoke at home 0.3 0.3 0.9 0.6 -0.7 0.3 -0.5 0.1 0.2 0.4 -0.8 0.6 -0.2 -1.0 0.7 -0.9 -0.3
Breastfed as a baby 0.7 0.9 3.7 1.4 0.1 -0.2 0.5 -1.4 0.0 -0.3 -1.1 0.3 0.5 1.0 1.1 -0.6 1.9
Tense / ‘highly strung’ 1.1 1.9 3.9 -1.4 -1.7 -0.4 1.4 -0.4 -0.9 -1.4 -1.0 2.0 1.9 0.4 -1.8 1.9 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 3.6 0.0 0.6 -0.1 -0.2 1.9 1.2 -0.2 0.3 -0.2 -1.4 -0.3 0.8 -0.7 -1.7
Hair/balding pattern: Pattern 4 0.9 2.1 6.1 2.3 1.5 -0.5 -0.8 1.0 1.5 2.4 -0.1 -0.5 -2.5 1.8 -0.8 -0.6 1.0
Birth weight of first child 0.6 1.1 4.7 -0.3 0.8 1.3 -2.2 -0.3 0.5 -0.2 -1.3 -1.7 0.3 -0.4 1.2 -1.1 -0.9
Peak expiratory flow (PEF) 1.5 3.5 11.0 -0.4 -3.3 -0.7 0.1 -2.6 -3.3 -0.2 -2.0 -0.6 2.2 0.5 -1.4 2.1 2.3
Pulse wave reflection index 0.8 1.0 6.3 -0.6 1.2 1.5 -2.5 -0.1 1.1 -0.1 0.3 -0.9 0.8 -0.4 0.2 -0.3 -1.2
Ever highly irritable/argumentative for 2 days 0.4 0.5 1.6 0.0 -0.6 -0.1 1.3 1.1 0.5 -0.2 -0.1 1.1 -1.1 -0.5 0.6 -0.4 -0.7
Loud music exposure frequency 0.9 0.9 4.7 0.5 -1.2 -2.2 0.1 -0.8 -0.1 -0.8 -1.5 -0.8 -0.7 -0.7 1.0 0.4 0.7
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 6.8 -2.6 1.2 -0.1 -0.6 0.4 0.8 1.0 0.5 -0.6 0.4 -1.4 -0.2 -0.7 -1.4
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.3 -0.3 -0.3 0.2 0.6 0.9 -0.9 0.9 0.7 0.2 -0.6 -0.2 -0.6 -1.1 -0.1
Blood clot in the leg (DVT) 0.6 0.8 2.3 1.2 0.2 -0.4 -1.5 0.6 0.3 1.2 0.7 -1.0 -0.7 1.1 -0.7 -1.1 -0.4
Medication: Paracetamol 1.3 2.1 6.0 1.4 2.4 -1.0 -2.1 -0.4 0.7 0.2 0.0 -2.3 -1.3 2.5 1.3 -0.2 1.3
Headache pain in last month 1.8 3.2 9.3 2.2 2.4 -1.2 -2.3 0.7 -1.3 -1.2 -0.3 -2.2 -0.9 3.1 -1.0 0.5 2.7
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 7.3 0.4 1.3 0.1 -1.9 0.2 -0.0 0.5 0.5 -1.6 -0.6 2.7 -0.3 -0.6 -0.1
Glaucoma (self-reported) 0.8 0.9 4.7 -0.1 -0.1 0.1 -1.1 0.1 -0.9 -2.2 -0.6 -1.3 1.2 -0.2 0.2 0.6 1.4
Gout (self-reported) 0.6 0.8 2.7 -1.1 -1.1 1.2 0.2 -0.6 0.4 -1.3 -0.3 -0.9 0.8 -0.6 -0.3 0.9 -1.6
Hypothyroidism/myxoedema (self-reported) 0.6 1.1 4.1 2.0 0.1 -1.0 -0.7 -0.2 0.9 1.4 0.9 -0.8 -0.5 0.2 1.2 -0.8 1.9
Medication: Amlodipine 1.2 1.6 6.3 -0.6 -1.2 -1.4 2.5 -0.7 -1.0 -1.4 -1.2 0.8 1.1 -0.5 -0.7 2.2 0.7
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.1 0.9 0.6 -1.1 -0.5 -1.0 1.7 0.6 -0.2 -1.2 -0.4 -0.5 1.8 -0.3 -0.4
Birth weight 1.0 2.2 5.9 1.4 1.6 -1.7 -2.4 0.8 2.0 0.8 0.0 -2.3 -1.7 1.8 0.1 -0.7 0.3
Chronic bronchitis/emphysema (mother) 1.4 1.6 9.4 -0.1 2.1 0.1 -1.8 1.3 3.1 1.1 0.5 -0.1 -0.9 1.0 0.4 -0.0 -0.5
High blood pressure (siblings) 1.7 2.4 7.5 -1.6 -1.6 0.4 1.3 -1.8 -1.2 -1.5 -1.5 -1.9 1.6 0.8 -1.0 2.7 1.4
Forced vital capacity (FVC), Best measure 0.8 2.8 11.7 -2.0 -0.5 2.5 -0.3 -1.6 -2.6 -0.7 0.0 -1.0 1.7 1.3 -3.4 1.1 1.0
Body fat percentage 0.4 1.8 8.5 2.3 0.4 -1.8 0.1 0.5 2.9 0.8 1.1 -1.1 -1.1 -0.8 1.5 0.3 0.3
Leg fat percentage (right) 0.5 1.6 6.2 2.5 0.0 -2.0 1.3 -0.2 2.2 0.5 0.3 0.2 -0.8 -0.6 1.7 0.6 1.3
Arm fat-free mass (right) 0.4 2.1 7.9 -1.9 0.8 2.1 -0.8 0.1 1.5 2.8 2.1 1.0 0.2 -0.4 -1.9 0.0 -0.7
Exposure to tobacco smoke outside home 1.5 2.0 11.8 0.0 0.9 -0.4 -0.6 0.1 3.4 2.3 1.3 0.0 -1.5 -0.5 1.7 -1.4 -0.4
Comparative body size at age 10 0.4 1.2 6.0 -0.3 -0.1 0.6 2.1 0.9 -0.3 -0.4 -0.3 2.4 0.0 -1.7 -1.0 -0.9 -0.8
Number of full brothers 1.1 1.4 7.6 1.2 0.6 0.7 -2.8 0.3 -0.1 0.4 -0.2 -2.2 -1.3 1.0 0.4 -0.6 1.2
Worry too long after embarrassment 1.3 2.1 10.1 -1.8 0.3 1.0 1.5 1.8 1.2 -0.1 1.1 3.2 -0.9 -1.9 -0.9 -0.5 -1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 5.5 0.6 -0.0 -2.2 -0.4 1.4 1.9 -0.3 -0.3 -0.5 -1.0 0.1 2.4 0.2 0.4
Wheeze or whistling in the chest in last year 0.8 1.5 11.5 0.6 0.4 -1.1 -1.0 -0.6 3.4 0.9 1.0 0.1 -0.7 0.1 1.9 -0.6 -0.0
Number of children fathered 0.9 1.0 4.4 -1.0 -0.8 -0.0 0.3 -1.3 0.1 -2.1 -0.6 -0.8 1.8 -0.7 0.9 0.5 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 4.0 -0.5 1.3 -0.4 -0.0 0.8 -0.2 1.6 0.9 -0.0 -0.8 0.3 -2.0 -0.4 -1.2
Age at first live birth 0.3 0.5 1.4 -0.8 -0.0 -0.1 0.8 1.1 0.9 0.7 0.8 -0.1 -1.2 0.5 -0.7 -0.4 0.3
Pulse wave peak to peak time 0.8 0.9 5.8 0.1 0.8 -0.4 -0.2 0.4 0.9 2.4 1.2 0.0 -1.6 0.9 0.0 -0.3 0.7
Health satisfaction 0.6 0.8 2.9 -0.5 0.7 1.7 -1.7 1.0 1.1 0.7 -0.2 -0.5 -0.5 -0.8 -0.6 -0.4 -0.6
Shortness of breath walking on level ground 0.3 0.3 1.0 -1.0 -0.3 -0.8 -0.4 -0.0 0.9 -0.2 0.1 -0.7 0.5 -0.3 -0.2 0.7 0.8
Qualifications: College or University degree 0.2 0.6 2.1 -0.7 1.5 1.1 0.2 0.2 0.2 0.5 0.2 0.5 1.0 0.9 0.8 -0.8 -1.1
Eye problems/disorders: None of the above 0.9 1.0 3.2 1.1 1.1 0.5 0.5 -1.0 1.8 0.9 1.2 1.0 -0.1 1.1 1.2 -0.9 -0.0
Mouth/teeth dental problems: Loose teeth 1.2 1.4 5.7 -0.2 -1.2 -0.3 -0.6 -2.0 0.8 -1.3 -1.1 -1.1 2.4 0.3 1.0 1.0 1.1
Emphysema/chronic bronchitis 1.0 1.1 5.1 1.7 -0.9 -0.5 -1.4 0.4 0.9 0.3 -0.7 -0.6 -0.1 2.3 1.0 -0.6 1.1
Medication for pain relief, constipation, heartburn 1.0 1.8 4.0 -1.7 -0.7 1.3 2.0 1.3 -0.5 0.0 0.2 1.9 0.1 -1.6 -2.0 0.7 -1.9
Neck or shoulder pain in last month 0.5 0.7 2.9 0.9 -0.9 -1.7 -0.5 -0.7 -1.2 -0.4 -0.9 0.4 0.5 0.3 -0.2 0.5 0.8
Medication: Blood pressure 0.3 0.6 2.0 0.5 -0.9 -0.5 1.0 -0.7 0.7 -0.1 -0.7 1.0 0.4 -1.4 -0.1 1.2 0.2
Angina (self-reported) 0.9 1.1 6.0 0.8 -0.8 1.1 2.4 0.5 0.1 0.5 -0.7 1.9 0.2 -1.2 -0.2 0.6 -1.0
Migraine (self-reported) 1.1 1.3 5.2 1.5 0.2 -2.3 -0.7 -0.7 -1.0 -0.9 -1.2 -1.6 -0.1 0.5 2.0 0.3 0.5
Medication: Ibuprofen 0.5 0.6 2.0 0.2 0.2 -1.2 0.5 -1.1 0.1 -1.0 0.2 0.1 1.0 1.4 0.1 0.8 1.0
Medication: Allopurinol 1.1 1.5 6.4 -0.3 -1.9 -0.1 1.5 -1.1 -0.9 -2.5 -1.7 0.6 0.7 -1.0 0.3 0.9 -1.0
Medication: Omeprazole 0.3 0.4 1.8 1.4 -0.5 -0.7 0.2 0.0 -0.3 0.1 -0.1 0.4 0.8 0.1 -0.3 1.0 0.6
Medication: Seretide 50 evohaler 1.1 1.2 4.4 0.7 1.0 -1.5 0.1 1.7 1.6 0.9 -0.3 -0.4 -2.1 -0.5 0.5 1.2 -0.8
Mean time to correctly identify matches 0.5 0.9 3.1 0.9 0.1 0.7 1.1 1.7 -0.4 1.2 0.3 1.0 -1.8 -0.2 -0.1 -1.3 -0.0
Heart disease (mother) 0.8 1.0 5.8 -0.5 0.7 1.3 2.4 0.3 1.1 -0.1 0.8 0.7 -1.4 0.5 0.8 -0.3 -0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 3.2 -0.9 0.1 -0.2 -1.8 0.9 1.5 0.5 1.7 -0.5 -0.5 0.3 -1.5 0.6 -1.4
Whole body fat mass 0.3 1.3 8.0 1.6 0.5 -0.9 -0.0 0.7 2.8 1.4 1.4 -0.7 -1.1 -0.5 0.7 0.1 0.1
Leg fat mass (right) 0.3 1.1 5.2 1.3 0.2 -1.3 0.6 0.2 2.3 1.6 1.1 0.3 -0.9 -0.9 0.7 0.1 0.4
Arm predicted mass (right) 0.4 2.2 8.2 -1.9 0.9 2.3 -1.0 0.3 1.4 2.9 2.1 1.0 0.3 -0.4 -2.0 0.0 -0.5
Pulse rate, automated reading 0.7 2.3 6.6 -0.0 -1.6 -0.6 1.9 1.4 -2.4 -0.0 0.5 2.0 -0.3 -2.6 -2.3 0.1 -1.5
Alcohol intake frequency. 0.3 0.7 2.7 1.6 0.4 -0.6 -0.7 -0.4 0.3 1.2 0.4 -0.5 -1.6 -0.4 0.9 -0.3 -0.7
Comparative height size at age 10 0.4 2.3 11.8 -0.4 0.7 1.0 -2.6 0.6 1.3 2.3 1.6 -3.4 -0.5 -0.0 0.3 -1.2 0.0
Number of full sisters 0.8 1.0 6.3 0.2 -0.2 -2.5 -0.1 1.1 -1.1 0.3 1.2 0.6 -1.3 -0.4 -0.9 0.6 -0.3
Suffer from ‘nerves’ 0.6 1.0 4.0 -1.1 0.7 -0.0 0.5 1.6 1.3 0.1 1.8 2.0 -0.2 0.2 -0.4 -0.0 0.6
Overall health rating 1.1 2.3 7.4 0.4 1.3 0.8 -1.8 1.5 2.7 1.9 2.2 0.3 -1.4 -0.8 1.2 -2.1 -0.3
Chest pain or discomfort 1.8 2.5 9.6 0.9 0.8 1.6 1.2 -0.1 1.8 0.8 1.0 2.0 -1.3 -0.3 2.5 -3.1 -1.8
Had major operations 0.8 1.0 3.4 -1.7 -0.9 -0.4 1.3 -1.8 1.0 -1.1 -0.3 0.1 0.4 -0.1 0.5 0.4 1.2
Age at last live birth 0.7 1.0 4.8 0.4 0.4 -0.8 -0.3 -0.4 1.4 -0.2 0.2 -0.6 -0.4 2.2 -0.2 0.5 2.2
Family relationship satisfaction 0.6 0.7 2.5 -0.8 -0.7 -0.1 -1.1 0.0 -0.6 0.0 -0.3 -0.2 1.6 -0.7 -1.3 1.6 0.5
Leg pain on walking 1.0 1.3 5.4 -0.2 1.1 0.6 -2.3 -0.4 1.5 1.2 -1.1 -1.3 0.5 0.7 1.9 -0.1 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 1.3 0.2 1.1 0.4 0.5 -0.2 -0.4 -0.7 0.7 -0.1 -0.1 0.1 -1.0 0.5 -0.7
Commuting to job workplace: Car/motor vehicle 1.4 1.6 6.9 -0.1 0.5 1.2 -1.5 -1.2 2.2 1.1 -0.1 -0.9 1.7 0.6 2.6 -0.5 -0.3
Illness, injury, bereavement, stress in last 2 years 2.2 2.7 8.2 0.7 -2.9 0.8 1.8 -0.8 -2.8 -1.5 -1.8 2.5 1.2 -1.3 -0.9 0.9 -0.6
Medication: Aspirin 0.6 0.8 2.4 1.0 -1.1 0.0 -1.0 -0.6 1.5 1.0 0.4 -1.5 -0.3 0.2 1.1 -0.4 0.6
Supplements: Vitamin C 1.7 2.0 6.7 0.8 -1.4 -1.4 0.8 -2.5 0.3 -0.2 -2.6 0.2 1.4 0.5 1.7 0.4 2.2
Knee pain experienced in last month 0.4 0.6 1.5 -0.7 -0.6 0.8 -0.8 -1.2 0.2 -0.8 0.3 0.4 1.2 0.8 0.2 0.2 1.2
Hypertension (Self-reported) 0.9 2.4 7.8 -0.1 -2.4 -1.9 1.6 -1.6 0.1 -1.3 -1.3 1.2 1.9 -1.5 -0.8 2.8 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.6 1.9 7.8 2.8 1.4 0.8 0.2 1.5 1.5 1.1 -0.3 2.2 -1.9 0.6 1.1 -0.4 -0.0
Illnesses of father: Heart disease 0.6 0.8 3.7 0.3 -0.5 1.9 1.8 -0.3 0.6 0.2 0.7 0.7 0.8 -0.6 -0.3 1.3 -0.2
Illnesses of siblings: Diabetes 0.4 0.4 1.9 -1.1 0.3 0.2 -0.5 0.1 0.4 -0.1 1.4 -0.2 0.6 -0.2 -0.5 1.2 -0.7
Smoking status: Previous 1.2 1.7 5.7 1.0 -2.4 -1.9 1.3 -0.8 -0.6 1.1 0.3 -0.1 0.7 1.3 -0.7 2.0 1.8
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 5.3 -1.2 2.3 0.1 -2.0 0.9 0.7 1.4 2.3 -1.8 -1.5 0.5 -1.4 -0.3 -0.5
Whole body fat-free mass 0.2 1.1 4.1 -1.4 0.6 1.5 -1.0 0.3 0.8 2.0 1.4 0.2 -0.1 0.2 -1.9 0.0 -0.1
Leg fat-free mass (right) 0.2 1.0 4.5 -1.3 0.5 1.0 -1.0 0.7 0.9 2.1 1.5 -0.4 -0.2 -0.0 -1.4 -0.3 -0.5
Arm fat percentage (left) 0.3 1.3 5.3 2.3 -0.6 -2.0 1.1 -0.1 1.8 0.0 0.4 -0.7 -0.8 -0.6 0.9 0.5 0.8
Average weekly red wine intake 0.5 0.8 3.4 -1.1 1.2 0.6 0.6 0.3 0.5 0.6 0.8 1.9 1.6 -0.4 -0.4 0.1 -0.3
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.4 -0.1 -0.5 -1.1 0.8 -0.6 -1.5 -0.6 -1.1 -0.1 -0.1 0.4 0.5 0.0 1.6
Mood swings 0.9 1.6 6.2 -0.3 0.6 -1.0 -1.1 1.5 1.7 1.9 2.5 0.3 -2.0 0.2 -0.4 -0.3 -0.7
Loneliness, isolation 0.6 0.8 3.3 -0.4 0.5 0.4 0.4 0.6 0.8 0.9 0.9 1.8 -1.0 -0.5 0.4 -1.6 -0.0
Long-standing illness, disability or infirmity 0.8 1.2 3.5 -1.0 1.5 0.5 0.2 1.1 1.6 1.9 1.9 0.5 -0.9 -0.4 1.0 0.1 0.0
Ever had bowel cancer screening 0.6 0.7 2.6 0.4 1.4 1.0 -1.2 -0.2 1.6 0.4 -0.4 -0.5 -0.6 0.9 0.7 -0.1 0.0
Diabetes diagnosed by doctor 2.1 3.4 14.6 0.2 -2.3 -0.5 -0.6 -1.7 1.3 -1.1 -1.7 0.8 3.8 -2.8 2.3 2.0 0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.0 3.4 0.2 0.2 0.3 0.0 -0.5 -1.1 -0.7 -0.3 1.6 1.8 0.2 -0.4 1.6 1.8
Friendships satisfaction 1.0 1.2 3.9 -0.7 -1.4 1.6 -0.6 -0.5 -1.7 -2.0 -1.2 0.1 1.4 -0.5 -0.8 0.4 0.0
Qualifications: nursing, teaching 0.4 0.7 2.4 -0.2 0.9 1.2 -0.6 -0.8 -0.3 1.0 -0.5 -0.5 0.0 -0.3 1.6 -1.3 -0.2
Commuting to job workplace: Walk 0.8 0.9 3.4 -0.1 -0.9 -0.1 0.9 0.9 -1.7 -1.3 -0.9 -0.3 0.1 -0.6 -1.8 0.6 0.8
Eye problems/disorders: Cataract 0.9 1.1 5.7 -0.2 -1.9 -0.9 1.1 0.6 -2.4 0.1 -1.5 0.5 0.0 0.6 -0.1 0.8 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 3.1 0.7 0.5 -1.2 0.4 1.0 -0.9 -0.1 0.3 1.8 0.1 0.2 -0.9 -0.0 1.0
Medication for cholesterol 2.7 4.0 9.9 -0.4 2.8 0.8 -2.6 3.1 1.2 2.5 2.9 -1.5 -2.3 0.9 -1.4 -1.9 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 6.2 0.1 0.4 -1.0 -1.3 -0.9 0.6 -0.4 -0.4 -2.5 -0.2 0.7 1.9 -1.4 1.6
Back pain experienced in last month 0.5 0.7 2.4 1.2 -1.6 0.4 0.1 -0.9 0.2 -1.5 0.4 -0.7 -0.0 0.9 0.2 -0.2 1.0
Mineral and other dietary supplements 0.5 0.7 3.9 0.6 -0.2 0.4 -0.5 0.8 -1.4 0.2 0.2 0.7 -1.1 -0.5 0.2 -2.0 0.3
Breast cancer (self-reported) 0.7 0.9 2.5 -0.6 0.1 1.1 -1.4 -1.2 0.7 -0.4 -1.6 -1.0 1.2 -0.7 0.9 0.1 -0.5
Asthma (self-reported) 0.9 1.9 6.7 -0.3 0.8 -2.2 -1.0 1.3 2.6 1.9 1.3 -0.7 -1.2 -1.2 1.3 -0.5 0.3
Osteoporosis (self-reported) 0.5 0.6 2.6 -1.6 -0.7 -0.2 -1.0 -0.2 -0.8 -0.9 1.1 -1.1 0.3 -0.1 -0.6 0.5 -0.3
Osteoarthritis (self-reported) 1.3 1.6 5.6 0.1 -2.0 2.4 -0.2 -1.4 -0.1 -1.5 -0.8 -0.1 1.5 1.5 0.2 0.4 1.9
Medication: Aspirin 0.5 0.7 2.2 1.2 -1.5 -0.3 -0.7 -0.8 1.1 0.7 -0.2 -1.4 -0.1 0.1 1.1 0.3 0.5
Medication: Gliclazide 1.5 1.7 5.9 1.1 -1.9 -0.4 -0.7 0.3 1.1 -1.2 -1.7 0.4 2.4 -1.3 1.8 1.3 -0.2
Illnesses of father: None of the above (group 1) 0.5 0.7 2.7 -0.5 -0.3 -0.0 -1.0 0.6 -0.6 -0.0 -0.7 -1.6 -1.1 0.1 -1.1 -1.3 -0.1
Smoking status: Current 0.5 0.8 3.0 -1.0 0.2 0.4 -1.1 1.0 0.3 -0.9 0.2 1.1 0.5 -1.2 -0.7 0.3 -1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.9 4.0 20.2 -1.5 -0.9 3.7 -0.1 -1.5 -4.5 0.5 -1.1 -2.4 1.4 -1.7 -2.0 -0.2 0.2
Whole body water mass 0.2 1.3 4.5 -1.5 0.5 1.5 -0.9 0.5 0.7 2.1 1.5 0.2 -0.2 0.1 -2.1 -0.1 -0.3
Leg predicted mass (right) 0.2 1.1 4.7 -1.3 0.6 1.0 -1.1 0.9 1.0 2.2 1.5 -0.3 -0.2 -0.1 -1.4 -0.2 -0.6
Arm fat mass (left) 0.2 0.8 3.6 0.9 0.0 -1.0 0.8 0.2 1.9 1.2 1.2 -0.0 -1.1 -0.8 -0.2 0.2 0.1
Number of self-reported non-cancer illnesses 0.6 1.1 8.0 -0.3 -0.1 -1.1 -0.4 -0.9 2.8 0.1 1.0 -0.3 0.1 -1.3 1.4 -0.3 0.0
Average weekly champagne plus white wine intake 0.6 0.8 2.4 0.1 -0.7 0.7 -1.1 -0.5 -0.1 -1.6 -0.9 -1.4 1.2 1.1 1.0 -0.5 0.3
Miserableness 0.6 1.1 4.3 -0.3 0.8 -0.6 0.4 1.4 1.2 1.2 2.1 1.3 -1.1 -1.0 1.1 -0.2 -0.2
Guilty feelings 1.1 1.6 6.8 -0.7 1.6 2.6 -1.0 2.3 1.2 0.6 1.3 0.9 -0.5 -0.1 -0.9 -1.2 -0.5
Wears glasses or contact lenses 1.0 1.1 7.0 2.6 -0.3 -1.1 -0.4 -0.5 0.7 -0.5 -1.2 -1.4 -0.4 1.2 0.7 0.6 0.5
Ever taken oral contraceptive pill 0.9 1.0 6.8 -2.6 -1.1 -0.1 -0.3 -0.3 -1.2 -0.9 0.5 -0.6 0.7 -0.5 -1.3 -0.1 -0.0
Hearing aid user 0.6 0.7 4.4 0.2 -0.1 -0.3 1.2 0.5 0.4 1.0 -0.5 0.9 0.1 -2.1 -0.4 -0.5 -1.0
Mother’s age at death 0.9 1.1 3.2 1.7 -1.7 -0.5 -1.6 0.2 0.0 -0.4 -1.6 -1.8 0.7 -0.3 0.4 0.1 -0.4
Financial situation satisfaction 0.6 0.7 2.3 -0.5 1.0 1.5 -1.1 0.3 0.2 1.1 1.4 -0.1 -0.1 -0.4 -1.0 -1.0 -0.5
Tinnitus: Yes, now most or all of the time 0.4 0.5 2.0 -0.1 1.4 0.2 -1.2 -0.5 1.2 0.5 0.1 -1.0 -0.1 0.4 0.2 0.5 -0.2
Commuting to job workplace: Public transport 0.4 0.4 1.9 -0.1 -0.6 0.5 0.7 0.2 -1.0 -1.4 -0.9 0.6 -0.4 -0.0 0.2 -0.5 -0.8
Eye problems/disorders: Glaucoma 0.9 1.1 5.0 -1.0 0.0 -0.2 -1.5 0.0 -0.7 -2.2 -0.5 -1.1 1.6 -0.1 -0.6 1.2 0.9
Medication: Blood pressure 0.5 0.9 2.9 -0.5 -1.4 -0.8 0.4 -1.4 -0.1 -0.2 -1.2 0.9 1.2 -0.9 0.2 1.7 -0.2
Pain type(s) experienced in last month: Hip pain 1.9 2.4 6.9 -2.3 0.5 1.3 -1.4 -0.0 2.0 0.9 2.6 -0.3 -0.2 -0.9 0.7 -1.9 -2.6
Supplements: Fish oil (including cod liver oil) 0.3 0.4 3.0 0.1 0.3 0.4 0.0 0.2 1.7 0.8 0.0 -0.6 0.4 -0.0 0.1 0.9 -0.4
High cholesterol (Self-reported) 1.2 2.1 16.6 -1.0 -1.7 -0.5 1.2 0.6 -0.1 0.8 0.3 2.0 -0.2 -4.1 0.1 -0.1 -1.4
Medication: Bendroflumethiazide 1.3 2.0 7.1 -0.6 -2.7 -0.3 0.5 -1.3 -0.8 -1.6 -2.0 1.2 1.7 -2.1 -0.1 1.4 -0.3
Medication: Paracetamol 0.7 1.1 4.4 0.7 2.1 -0.7 -1.7 -0.2 1.0 0.5 0.4 -1.5 -0.5 1.5 0.4 0.8 0.8
Medication: Lisinopril 1.1 1.5 4.3 0.7 -1.6 0.5 0.2 -0.6 -1.2 -1.9 -2.1 -0.0 1.9 -0.5 0.1 1.9 0.6
Medication: Atorvastatin 1.1 1.4 5.3 0.0 0.8 1.9 -0.0 0.8 2.3 1.1 0.8 -0.2 -0.9 -0.4 1.3 -2.0 -0.9
Illnesses of father: High blood pressure 0.9 1.1 3.9 0.4 0.9 -1.1 0.9 -2.0 0.3 0.3 -0.6 0.9 0.3 1.3 -0.1 1.7 1.4
Alcohol drinker status: Never 0.4 0.5 2.2 -0.1 0.4 0.4 -1.0 -0.9 0.7 1.5 0.4 -1.1 0.1 0.7 0.2 0.1 -0.5
Ever smoked 0.6 1.0 4.7 0.7 -2.2 -1.5 0.8 1.1 -0.9 -0.1 0.3 -0.2 -0.2 0.8 -0.5 1.6 0.4
Basal metabolic rate 0.2 1.1 4.5 -1.1 0.8 1.1 -0.9 0.4 1.3 2.1 1.6 0.1 -0.3 0.1 -1.5 -0.1 -0.2
Leg fat percentage (left) 0.4 1.5 4.9 2.2 0.1 -1.3 1.4 -0.3 2.2 0.8 0.2 0.2 -0.6 -0.7 1.9 0.6 1.3
Arm fat-free mass (left) 0.3 1.7 6.5 -1.7 1.0 1.8 -0.3 0.3 1.1 2.5 1.8 1.1 -0.3 -0.1 -2.0 0.1 -0.4
Number of operations (self-reported) 0.4 0.6 1.5 -1.2 -1.1 -0.1 0.3 -0.6 0.7 -0.6 0.0 -1.1 0.4 -1.2 0.6 1.1 -0.4
Average weekly beer plus cider intake 0.6 0.9 3.7 0.1 -1.9 -0.8 -0.6 0.8 -0.9 -0.4 0.5 -0.1 -0.5 1.0 -1.3 1.5 0.7
Irritability 0.3 0.5 1.8 0.3 0.1 -0.8 -0.4 -0.5 0.4 0.0 1.2 -0.4 -0.8 1.3 0.3 -0.3 1.0
Risk taking 0.4 0.6 3.1 -1.8 0.5 -0.3 0.2 -1.0 0.2 -0.1 0.5 -0.2 -0.2 1.0 -1.3 0.7 -0.7
Ever had prostate specific antigen (PSA) test 0.3 0.4 2.1 -0.7 0.9 -0.3 -0.4 -0.3 0.5 -0.7 -0.8 -1.4 -0.2 0.5 0.3 0.0 -0.2
Fractured/broken bones in last 5 years 0.7 0.9 3.2 -0.5 0.2 -1.1 -1.3 1.5 1.8 1.2 0.3 -0.5 0.2 -0.8 -0.1 0.9 -1.2
Age started oral contraceptive pill 0.6 0.8 2.0 0.9 -0.7 0.3 -0.9 -0.4 1.4 -1.0 -0.7 -1.1 1.0 0.7 1.3 -0.5 -0.4
Diastolic blood pressure, automated reading 0.7 2.0 6.5 -0.1 -1.4 -1.1 1.9 0.8 -1.9 1.9 -0.1 0.6 0.0 0.9 -2.3 2.6 0.6
Ever depressed for a whole week 0.4 0.5 3.0 0.1 -0.5 0.8 -1.7 1.1 0.8 -0.0 -0.3 -0.9 -0.4 0.2 0.5 -0.4 -0.2
Unable to work because of sickness or disability 0.8 1.1 5.4 0.6 0.4 -0.1 -1.7 1.0 1.0 0.0 0.3 -2.3 -0.6 1.6 0.5 -0.0 1.2
Commuting to job workplace: Cycle 0.4 0.4 2.2 0.6 -0.1 0.3 0.2 0.4 -1.5 0.1 0.3 -0.2 -1.3 0.2 -0.7 0.3 -0.7
Myopia 1.1 1.6 6.4 1.2 1.2 -0.4 -0.1 1.7 1.2 1.1 2.5 -0.4 -1.7 1.3 -1.2 0.5 0.5
Vascular/heart problems diagnosed by doctor 1.1 3.1 8.1 0.2 2.8 1.6 -2.4 2.2 0.4 1.3 1.6 -1.4 -1.9 1.9 0.6 -2.7 -1.1
Cholesterol lowering medication 0.4 0.6 2.7 -0.2 -0.8 -0.5 1.0 -0.4 0.5 0.1 -0.7 0.7 0.7 -1.6 0.3 1.5 0.2
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 2.2 1.5 0.2 -0.6 0.6 0.4 -0.4 0.7 0.3 0.2 -0.1 0.0 -0.4 0.6 0.8
Pain experienced in last month 0.3 0.4 2.2 0.1 -0.5 -0.5 1.3 0.1 -0.1 0.2 -1.5 -0.7 -0.5 -0.3 0.4 0.6 -0.4
Supplements: Calcium 0.7 0.8 3.2 -1.6 -0.2 0.6 0.9 1.1 -1.0 0.2 0.5 0.3 -0.2 -0.5 -1.8 0.5 -1.1
Basal cell carcinoma (self-reported) 6.0 7.1 18.1 3.1 -1.9 -2.6 -0.6 -2.4 -1.8 -3.8 -4.2 -0.2 3.1 2.1 1.5 3.7 2.9
Heart attack/myocardial infarction (self-reported) 1.4 1.8 7.1 1.8 -0.6 0.4 -0.3 -0.7 0.5 2.3 0.5 -0.8 -1.5 -0.1 2.3 -2.7 0.5
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.3 1.2 0.6 -0.0 -1.5 0.6 0.3 1.2 0.7 -0.7 -1.0 1.4 -0.6 -1.4 -0.6
Heart disease (siblings) 1.0 1.2 4.0 0.8 -1.2 1.7 2.0 -1.3 -0.0 -0.2 -1.2 0.6 1.1 1.2 0.6 0.8 0.7
Alcohol drinker status: Previous 0.8 0.9 3.0 0.5 -1.1 -0.5 -0.9 1.6 -0.2 1.5 0.1 -0.8 -0.8 -1.7 -0.2 0.2 -1.0
Pack years of smoking 0.6 0.8 4.5 0.1 -0.3 1.3 -0.5 -0.5 2.1 0.3 0.5 -0.1 0.7 0.3 1.7 -0.8 -0.3
Impedance of whole body 0.4 2.2 7.6 2.3 0.3 -2.2 -2.1 0.1 1.1 -1.0 -0.2 -2.3 -0.3 0.3 2.8 -0.8 0.6
Leg fat mass (left) 0.3 1.1 5.8 1.2 0.2 -1.1 0.5 0.0 2.4 1.6 1.0 0.1 -0.7 -0.9 0.9 0.2 0.6
Arm predicted mass (left) 0.3 1.5 6.2 -1.6 0.9 1.8 -0.6 0.1 1.0 2.5 1.6 0.8 -0.2 -0.1 -1.9 -0.0 -0.5