[Hub]/) : Traits : Lung FVC :

chr7:25,715,984-28,468,319

Best TWAS P=9.07e-20 · Best GWAS P=6.94e-23 conditioned to 0.00205

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SKAP2 0.12 0.08 lasso 1 0.08 1.7e-09 5.4 -5.4 6.9e-08 0.02 0.98 0.02 FALSE
2 GTEx Adipose Visceral Omentum AC004540.4 0.15 0.00 enet 29 0.03 1.5e-02 3.5 5.8 6.8e-09 -0.01 0.13 0.09 TRUE
3 METSIM Adipose HOXA4 0.04 0.02 blup 391 0.02 8.3e-04 5.5 5.8 5.7e-09 -0.03 0.31 0.62 FALSE
4 ROSMAP Brain Pre-frontal Cortex SKAP2 0.15 0.14 bslmm 626 0.14 4.0e-17 5.6 -6.8 1.5e-11 0.04 0.96 0.04 TRUE
5 YFS Blood SKAP2 0.57 0.62 bslmm 639 0.64 4.0e-285 -4.5 5.4 6.5e-08 -0.11 1.00 0.00 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA0087 0.13 0.02 enet 24 0.06 3.5e-13 2.0 5.5 3.0e-08 -0.08 0.93 0.04 TRUE
7 The Cancer Genome Atlas Thyroid Carcinoma JAZF1 0.12 0.09 lasso 4 0.09 2.1e-09 -8.7 -9.1 9.1e-20 0.82 0.03 0.97 TRUE